| bartonella and rickettsia in fleas and lice from mammals in south carolina, u.s.a. | species in the genera bartonella and rickettsia are vector-borne pathogens of humans and domestic animals. the natural reservoirs and enzootic transmission cycles of these bacteria are poorly known in south carolina. thirteen species of lice and fleas were collected from urban animals and screened for the presence of bartonella and rickettsia by pcr amplification using genus-specific primers. bartonella henselae was present in cat fleas (ctenocephalides felis) from virginia opossums (didelphis v ... | 2005 | 16599169 |
| molecular evidence for novel bartonella species in trichobius major (diptera: streblidae) and cimex adjunctus (hemiptera: cimicidae) from two southeastern bat caves, u.s.a. | | 2005 | 16599175 |
| secondary unilateral glaucoma and neuroretinitis: atypical manifestation of cat-scratch disease. | | 2006 | 16604397 |
| experimental infection of human body lice with acinetobacter baumannii. | the human body louse is currently recognized as a vector of rickettsia prowazekii, borrelia recurrentis, and bartonella quintana. previous studies have reported the isolation of acinetobacter baumannii from the body lice of homeless patients. to study how the body louse acquires a. baumannii, we infected a rabbit by infusing 2 x 10(6) colony-forming units of the louse strain of a. baumannii. two hundred body lice were infected by feeding on the bacteremic rabbit and compared with 200 uninfected ... | 2006 | 16606978 |
| bartonella species in rodents and shrews in the greater jakarta area. | in february 2004, we captured 221 rodents and shrews in the greater jakarta area as part of a study to determine the prevalence of rodent-associated vector-borne infections. microscopic examination of blood smears revealed 6% (13/218) to be positive for bartonella spp. the corresponding dna samples, either from blood blots or frozen spleen pieces and from fleas collected on these animals, were tested for evidence of bartonella infection by pcr, targeting the portions: 378bp and 930bp of the citr ... | 2005 | 16610656 |
| [fleas and diseases transmissible to man]. | fleas are wingless insects that parasitize mammals and more rarely birds. they are able to jump and may bite people. adult fleas are hematophagous. the impact of fleas on public health is related to their ability to act as vectors for transmission of infectious agents during blood meals. the purpose of this article is to describe fleas and the diseases that they transmit to humans. special focus is placed on epidemiological aspects. | 2006 | 16615611 |
| bartonella henselae pap31, an extracellular matrix adhesin, binds the fibronectin repeat iii13 module. | bartonella henselae wound-associated infections suggest involvement of extracellular matrix molecules in adhesion and invasion. pap31 was previously identified as a hemin-binding protein. our recent studies suggest the protein is an adhesin that is recognized by the host's immune systems. in this study we examined the interactions of b. henselae pap31 with fibronectin (fn), heparin (hep), and human umbilical vein endothelial cells (huvecs). the cloned gene was expressed in escherichia coli, and ... | 2006 | 16622186 |
| cat-scratch disease in veterinary-associated populations and in its cat reservoir in taiwan. | in taiwan, the first human case of cat-scratch disease (csd) was diagnosed by a serologic test in 1998. since then, no studies have been conducted to understand the epidemiology of the infection in taiwan. therefore, this study is the first epidemiologic survey of csd in cats and humans in this country. using veterinary-associated individuals as the study population, it was identified that 1.7% of them were seropositive for b. henselae, and residence was the only factor associated with seroposit ... | 2006 | 16641017 |
| images in clinical medicine. cat scratch disease lymphadenopathy. | | 2006 | 16641391 |
| parotid mass due to cat scratch disease. | cat scratch disease (csd), due to bartonella henselae, is a self-limited chronic lymphadenopathy. a previously healthy 22-year-old woman presented with a palpable painful swelling in the right submandibular region accompanied by enlarged cervical lymph nodes. a diagnosis of b. henselae infection was made according to her personal history that divulged frequent contacts with cats and to a high titre of immunoglobulin g (igg) and igm antibodies for this agent. the patient improved within 1 month w ... | 2006 | 16669837 |
| systemic granulomatous disease and sialometaplasia in a dog with bartonella infection. | systemic granulomatous disease involving the spleen, heart, lymph nodes, omentum, liver, kidney, lung, mediastinum, and salivary glands developed in an 8-year-old rottweiler. the dog also had sialometaplasia of both submandibular salivary glands. bartonella henselae and b. vinsonii subsp. berkhoffii dna was amplified from the salivary gland by polymerase chain reaction analysis. bartonellae may be the cause of this systemic disease, but to the authors' knowledge, involvement of omentum, mediasti ... | 2006 | 16672593 |
| model structure of the prototypical non-fimbrial adhesin yada of yersinia enterocolitica. | non-fimbrial adhesins, such as yersinia yada, moraxella uspa1 and a2, haemophilus hia and hsf, or bartonella bada represent an important class of molecules by which pathogenic proteobacteria adhere to their hosts. they form trimeric surface structures with a head-stalk-anchor architecture. whereas head and stalk domains are diverse and appear (frequently repetitively) in different combinations, the anchor domains are homologous and display the properties of autotransporters. we have built a mole ... | 2006 | 16675268 |
| [study on bartonella species in rodents in western yunnan, china]. | to study the infection status of bartonella spp. in rodents in western part of yunnan province. | 2005 | 16676607 |
| emergence of distinct genetic variants in the population of primary bartonella henselae isolates. | bartonella henselae isolates from different hosts display a marked genetic heterogeneity, as determined by pulsed-field gel electrophoresis (pfge). the aim of the present study was to determine whether different genetic variants may coexist within the population of distinct b. henselae isolates and could be detected by pfge. three primary b. henselae isolates and the b. henselae reference strains atcc 49793 and 49882 were subjected as single colony derived cultures in quadruplicate to pfge analy ... | 2006 | 16697237 |
| autoimmunohistochemistry: a new method for the histologic diagnosis of infective endocarditis. | although the pathologic examination of cardiac valves remains the reference standard for the diagnosis of infective endocarditis, the detection of microorganisms often poses a challenge for pathologists. this can be done by use of nonspecific histochemical stains or by immunohistochemical analysis, but specific antibodies are often not available. we describe a novel method for the detection of microorganisms in valve specimens from patients with infective endocarditis. | 2006 | 16703515 |
| bartonella spp. in pets and effect on human health. | among the many mammals infected with bartonella spp., pets represent a large reservoir for human infection because most bartonella spp. infecting them are zoonotic. cats are the main reservoir for bartonella henselae, b. clarridgeiae, and b. koehlerae. dogs can be infected with b. vinsonii subsp. berkhoffii, b. henselae, b. clarridgeiae, b. washoensis, b. elizabethae, and b. quintana. the role of dogs as an important reservoir of bartonella spp. is less clear than for cats because domestic dogs ... | 2006 | 16704774 |
| new insight into the diagnosis of fastidious bacterial endocarditis. | sterile blood cultures are noted in one third of patients with infectious endocarditis. although in half of cases this is due to previous antibiotic therapy, in the other half, the aetiology of culture-negative endocarditis is intracellular bacteria such as coxiella burnetii or fastidious growing bacteria. although it was previously considered that the prevalence of such organisms was identical throughout the world, recent investigations on bartonella endocarditis clearly showed that the aetiolo ... | 2006 | 16706783 |
| environmental signals generate a differential and coordinated expression of the heme receptor gene family of bartonella quintana. | of all bacteria, bartonella quintana has the highest reported in vitro hemin requirement, yet an explanation for this remains elusive. to produce diseases such as trench fever, endocarditis, and bacillary angiomatosis, b. quintana must survive and replicate in the disparate environments of the pediculus humanus corporis (body louse) gut and the human vasculature. we previously identified a five-member family of hemin binding proteins (hbps) synthesized by b. quintana that bind hemin on the outer ... | 2006 | 16714552 |
| binding of bartonella henselae to extracellular molecules: identification of potential adhesins. | bartonella henselae, the etiologic agent of cat scratch disease, bacillary angiomatosis and other clinical syndromes initiates infection through a trauma or wound to the skin suggesting involvement of extracellular matrix molecules. we have demonstrated in this study that b. henselae bound strongly fibronectin, collagen ix and x, but comparatively less laminin and collagen iv. b. henselae bound primarily the n- and c-terminal heparin (hep-1 and hep-2, respectively) and the gelatin-binding domain ... | 2006 | 16725305 |
| louse-borne bacterial pathogens in lice (phthiraptera) of rodents and cattle from egypt. | we collected 1,023 lice, representing 5 species, from rats and domestic cattle throughout 13 governorates in egypt and tested these lice for anaplasma marginale, bartonella spp., brucella spp., borrelia recurrentis, coxiella burnetii, francisella tularensis, and rickettsia spp. by pcr amplification and sequencing. five different louse-borne bacterial agents were detected in lice from rodents or cattle, including "bartonella rattimassiliensis", "b. phoceensis", and bartonella sp. near bartonella ... | 2006 | 16729688 |
| bartonella quintana coinfection with mycobacterium avium complex and cmv in an aids patient: case presentation. | as a greater number of hiv-infected patients survive despite profound immunodepression due to medical progress, we face complex infection with multiple agents in aids-patients. | 2006 | 16732891 |
| evaluation of the relationship between causative organisms and clinical characteristics of infective endocarditis in dogs: 71 cases (1992-2005). | to evaluate microbiologic findings in dogs with infective endocarditis (ie) and determine whether there were differences in clinical features of disease caused by different groups of infective agents. | 2006 | 16740074 |
| multifocal osteomyelitis in a child: a rare manifestation of cat scratch disease: a case report and systematic review of the literature. | we present a case of a 9-year-old immunocompetent girl who presented with pain in her left elbow and a painful swelling at her left clavicle. she had no lymphadenopathy or fever. four hot spots were seen at her left clavicle, proximal and distal left humerus and lumbo-sacral spine on a bone scan. a magnetic resonance imaging showed an inflammatory process with bone destruction at her clavicle. serological testing and polymerase chain reaction performed on a bone biopsy identified a bartonella he ... | 2006 | 16751739 |
| aetiological diagnosis of infective endocarditis by direct amplification of rrna genes from surgically removed valve tissue. an 11-year experience in a finnish teaching hospital. | the aetiology of infective endocarditis (ie) can be determined directly from surgically removed valve tissue using broad-range bacterial rdna polymerase chain reaction (pcr) followed by sequencing. we sought to assess the value of this methodology in a routine clinical setting. | 2006 | 16754257 |
| [submandibular tumor]. | | 2006 | 16756901 |
| isolation of bartonella henselae dna from the peripheral blood of a patient with cat scratch disease up to 4 months after the cat scratch injury. | we report the case of a girl with cervical lymphadenitis and a persistent primary lesion of cat scratch disease (csd). bartonella henselae dna was isolated from plasma samples collected 3 and 4 months after the cat scratch, indicating that recurrent and long-term shedding of bartonella dna into peripheral blood may occur in typical csd. | 2006 | 16757642 |
| etiological diagnosis of blood-culture-negative endocarditis. | | 2006 | 16762253 |
| [endocarditis due to bartonella spp. three new clinical cases and spanish literature review]. | infections by bartonella spp. include a wide spectrum of emerging and re-emerging infectious diseases, such as culture-negative endocarditis. | 2006 | 16762254 |
| possible role of tick-borne infection in "cat-scratch disease": comment on the article by giladi et al. | | 2006 | 16802385 |
| borrelia, coxiella, and rickettsia in carios capensis (acari: argasidae) from a brown pelican (pelecanus occidentalis) rookery in south carolina, usa. | argasid ticks are vectors of viral and bacterial agents of humans and animals. carios capensis, a tick of seabirds, infests the nests of brown pelicans, pelecanus occidentalis, and other ground nesting birds along the coast of south carolina. this tick is associated with pelican nest abandonment and could pose a threat to humans visiting pelican rookeries if visitors are exposed to ticks harboring infectious agents. we collected ticks from a pelican rookery on deveaux bank, south carolina and sc ... | 2006 | 16821092 |
| multispacer typing to study the genotypic distribution of bartonella henselae populations. | bartonella henselae, a worldwide fastidious bacterium, has a feline reservoir and is pathogenic for humans. however, the relationship between human and cat isolates of b. henselae, as well as its population dynamics and geographic heterogeneity, is not fully understood, in part because of the absence of appropriate typing methods. multilocus sequence typing (mlst), the most discriminatory genotyping method for b. henselae, identified seven genotypes and suggested that human isolates arose from a ... | 2006 | 16825371 |
| disseminated bartonella infection following liver transplantation. | bartonella henselae has not only been identified as the causative agent of cat scratch disease, but it is also associated with other significant infectious syndromes in the immunocompromised population. we describe two cases of b. henselae associated diseases in liver transplant recipients who both had contact with cats. the first recipient developed localized skin manifestation of bacillary angiomatosis in association with granulomatous hepatitis. he tested positive for immunoglobulin g (igg) a ... | 2006 | 16827686 |
| rodent-associated bartonella febrile illness, southwestern united states. | serum specimens from 114 patients hospitalized with a febrile illness were tested with an indirect immunofluorescence assay (ifa) using bartonella antigens prepared from 6 species of sigmodontine rodents and 3 known human bartonella pathogens: b. henselae, b. quintana, and b. elizabethae. acute- and convalescent-phase serum samples from 5 of these patients showed seroconversion with an ifa titer >512 to rodent-associated bartonella antigens. the highest titer was against antigen derived from the ... | 2006 | 16836824 |
| surveillance of egyptian fleas for agents of public health significance: anaplasma, bartonella, coxiella, ehrlichia, rickettsia, and yersinia pestis. | serologic surveys in egypt have documented human and animal exposure to vector-borne bacterial pathogens, but the presence and distribution of these agents in arthropods has not been determined. between july 2002 and july 2003, fleas were collected from 221 mammals trapped in 17 cities throughout egypt. a total of 987 fleas were collected, representing four species (ctenocephalides felis, echidnophaga gallinacea, leptopsylla segnis, and xenopsylla cheopis); 899 of these fleas were x. cheopis fro ... | 2006 | 16837707 |
| [diagnostics of human granulocytic anaplasmosis]. | diagnostics of human granulocytic anaplasmosis. human granulocytic anaplasmosis is one of recently emerging tick-borne diseases. the paper summarizes current opinions on diagnostics of this zoonosis, including the recent recommendations of escar (european society of clinical microbiology and infectious diseases study group on coxiella, anaplasma, rickettsia and bartonella). | 2005 | 16838619 |
| [capreolus capreolus and ixodes ricinus as a reservoir of bartonella in north-western poland]. | capreolus capreolus and ixodes ricinus as a reservoir of bartonella in north-western poland. the purpose of the study was to assess the prevalence bartonella in capreolus capreolus from north-western poland forest. supplementary, ticks infesting roe deer were also screened in order to ascertain their role as vectors and reservoirs of bartonella. the samples of blood from 98 animals from north-western poland were pcr-screened. bartonella dna was detected by using primers complementary to the inte ... | 2005 | 16838623 |
| prevalence of mycoplasma haemofelis, 'candidatus mycoplasma haemominutum', bartonella species, ehrlichia species, and anaplasma phagocytophilum dna in the blood of cats with anemia. | hemoplasmas are known causes of anemia in some cats and some bartonella species have been associated with anemia in people and in dogs. in this retrospective study, we used polymerase chain reaction (pcr) assays to determine the prevalence rates of mycoplasma haemofelis, 'candidatus m haemominutum', a phagocytophilum, ehrlichia species, and bartonella species dna in the blood of cats with anemia and a control group of healthy cats. dna of the organisms was amplified from 22 of 89 cats with anemi ... | 2007 | 16846745 |
| american association of feline practitioners 2006 panel report on diagnosis, treatment, and prevention of bartonella spp. infections. | | 2006 | 16846781 |
| bartonella spp. in deer keds, lipoptena mazamae (diptera: hippoboscidae), from georgia and south carolina, usa. | deer keds, lipoptena mazamae (diptera: hippoboscidae), were collected from white-tailed deer (odocoileus virginianus) and humans in georgia and south carolina, usa (1 october 2001-6 january 2005) and screened for the presence of dna from bartonella spp. forty deer keds were screened for bartonella spp. by polymerase chain reaction using primers specific to the riboflavin synthase gene (ribc) of bartonella. bartonella species closely related to bartonella schoenbuchensis and to the etiologic agen ... | 2006 | 16870863 |
| first evidence of feline herpesvirus, calicivirus, parvovirus, and ehrlichia exposure in brazilian free-ranging felids. | serum samples from 18 pumas (puma concolor), one ocelot (leopardus pardalis), and two little spotted cats (leopardus tigrinus) collected from free-ranging animals in brazil between 1998 and 2004 were tested by indirect immunofluorescence (ifa) for antibodies to feline herpesvirus 1 (fhv 1), calicivirus (fcv), coronavirus (fcov), parvo-virus (fpv), ehrlichia canis, anaplasma pha-gocytophilum, and bartonella henselae. serum samples also were tested, by western blot and elisa, for feline leukemia v ... | 2006 | 16870878 |
| [study on bartonella vinsonii berkhoffii isolated from blood of native dogs in china]. | to isolate and identify bartonella strains from native dogs in shandong province in china. | 2006 | 16875539 |
| cloning, characterization, and expression of bartonella henselae p26. | in order to identify immunoreactive bartonella henselae proteins, b. henselae antiserum from an experimentally infected cat was used to screen a b. henselae genomic dna expression library. one immunoreactive phage clone contained a gene (p26) with significant nucleotide identity with orthologs in brucellae, bartonellae, and several plant-associated bacteria. p26 gene sequences from four b. henselae strains, one b. koehlerae strain, and one b. clarridgeiae strain were cloned. comparative nucleoti ... | 2006 | 16893981 |
| broad-range polymerase chain reaction for the diagnosis of bartonella henselae endocarditis. | we present a case of subacute bacterial endocarditis in a 10-year-old girl with di-george syndrome, congenital heart disease, and mild immunodeficiency. she was afebrile at initial presentation but was found to have massive splenomegaly, and signs of congestive heart failure. no causative organism could be identified on routine blood and tissue cultures. a detailed clinical history revealed a history that she had been scratched by a cat and developed intermittant fevers over 3 months. bartonella ... | 2006 | 16898887 |
| description of pseudochrobactrum gen. nov., with the two species pseudochrobactrum asaccharolyticum sp. nov. and pseudochrobactrum saccharolyticum sp. nov. | two gram-negative, rod-shaped, oxidase-positive, non-spore-forming, non-motile bacteria (ccug 46016(t) and ccug 33852(t)), isolated from a knee aspirate of a 66-year-old man and an industrial glue, respectively, were studied for their taxonomic position. on the basis of chemotaxonomic data [i.e. major ubiquinone (q-10), major polar lipids (phosphatidylethanolamine, phosphatidylglycerol and phosphatidylcholine) and major fatty acids (c(18 : 1)omega7c and c(19 : 0) cyclo omega8c)] and 16s rrna gen ... | 2006 | 16902015 |
| ixodes frontalis and avian tick-related syndrome in the united kingdom. | this study aimed to characterise tick species responsible for avian tick infestations in the uk, to analyse various risk factors for tick-related syndrome in tick-infested birds and to test samples for the presence of certain tick-transmitted pathogens. | 2006 | 16911113 |
| in vitro susceptibility of bartonella species to 17 antimicrobial compounds: comparison of etest and agar dilution. | in vitro susceptibility testing of 31 bartonella spp. strains including 21 bartonella henselae isolates was performed for 17 antimicrobial agents (telithromycin, four macrolides, five fluoroquinolones, five aminoglycosides, doxycycline and rifampicin). | 2006 | 16916864 |
| serological and molecular evidence of exposure to arthropod-borne organisms in cats from northeastern spain. | one hundred sixty-eight cat sera from spain were tested for igg antibodies to rickettsia conorii (rc), ehrlichia canis (ec), anaplasma phagocytophilum (ap) and bartonella henselae (bh) antigens using ifa and for felv antigen and fiv antibody by elisa. for 47 whole blood samples, pcr testing was performed for rickettsia, ehrlichia and bartonella. seroprevalences were: bh (71.4%), rc (44%), ec (11.3%), felv (8.5%), fiv (7.4%) and ap (1.8%). bh antibodies were associated with seroreactivity to both ... | 2006 | 16919405 |
| [a case of cat scratch disease in a patient with diabetes mellitus and chronic renal failure]. | the article describes a case of cat scratch disease in a female patient with severe chronic pathology. this relatively rare disease was manifested by regional (in the site of microbial intrusion) lymphadenopathy, and general infectious syndrome. the presence of oncohematological process was excluded without biopsy; serologic examination with bartonella antibodies confirmed the diagnosis. combined treatment with two antibiotics, rifampicin and doxycycline, was successful. the article stresses tha ... | 2006 | 16924805 |
| bartonella quintana variably expressed outer membrane proteins mediate vascular endothelial growth factor secretion but not host cell adherence. | bartonella quintana causes trench fever, endocarditis, and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis in humans. little is known about the interaction of this pathogen with host cells. we attempted to elucidate the interaction of b. quintana with human macrophages (thp-1) and epithelial cells (hela 229). remarkably, only b. quintana strain jk-31 induced secretion of vascular endothelial growth factor (vegf) from thp-1 and hela 229 cells upon infection similar ... | 2006 | 16926391 |
| autocrine role for interleukin-8 in bartonella henselae-induced angiogenesis. | the gram-negative bacterium bartonella henselae is capable of causing angiogenic lesions as a result of infection. previously, it has been shown that b. henselae infection can result in production of the chemokine interleukin-8 (il-8). in this study, we demonstrated that monocytes, endothelial cells, and hepatocytes produce il-8 in response to b. henselae infection. we also investigated the role of il-8 in b. henselae-induced endothelial cell proliferation and capillary tube formation. both in v ... | 2006 | 16926411 |
| systemic cat scratch disease. | systemic cat scratch disease (csd) is often associated with prolonged fever and microabscesses in the liver and/or spleen. we report a case of systemic csd with hepatic, splenic and renal involvement in an aboriginal child in taiwan. a previously healthy 9-year-old girl had an intermittent fever for about 17 days, and complained of abdominal pain, headache and weight loss. abdominal computed tomography showed multiple tiny hypodense nodular lesions in the spleen and both kidneys. laparotomy reve ... | 2006 | 16935770 |
| genome rearrangements, deletions, and amplifications in the natural population of bartonella henselae. | cats are the natural host for bartonella henselae, an opportunistic human pathogen and the agent of cat scratch disease. here, we have analyzed the natural variation in gene content and genome structure of 38 bartonella henselae strains isolated from cats and humans by comparative genome hybridizations to microarrays and probe hybridizations to pulsed-field gel electrophoresis (pfge) blots. the variation in gene content was modest and confined to the prophage and the genomic islands, whereas the ... | 2006 | 16936024 |
| molecular characterization of resistance to macrolides in bartonella henselae. | we selected in vitro erythromycin-resistant strains of bartonella henselae. the mutants obtained had point mutations in domain v of 23s rrna and/or in ribosomal protein l4. one lymph node of a patient with cat-scratch disease had such a mutation in 23s rrna, suggesting that natural resistant strains may infect humans. | 2006 | 16940128 |
| case records of the massachusetts general hospital. case 27-2006. a 17-year-old boy with fever and lesions in the liver and spleen. | | 2006 | 16943407 |
| analysis of data in 30 patients with cat scratch disease without lymphadenopathy. | the prominent clinical manifestation of cat scratch disease is regional lymphadenopathy at the site of the cat scratch or bite, associated with fever or general symptoms. a serological study of 540 patients with either lymphadenopathy, persistent fever, or pet ownership disclosed that 30 (16.1%) of the 186 patients with a serological diagnosis of cat scratch disease had no regional lymphadenopathy, and in these 30 patients, the absence of lymphadenopathy was closely related to the presence of pe ... | 2006 | 16944264 |
| prevalence of dna of mycoplasma haemofelis, 'candidatus mycoplasma haemominutum,' anaplasma phagocytophilum, and species of bartonella, neorickettsia, and ehrlichia in cats used as blood donors in the united states. | to identify the prevalence of dna of mycoplasma haemofelis; 'candidatus mycoplasma haemominutum'; anaplasma phagocytophilum; and species of bartonella, neorickettsia, and ehrlichia in blood of cats used as blood donors in the united states. | 2006 | 16948578 |
| prevalence of bartonella henselae antibodies in serum of cats with and without clinical signs of central nervous system disease. | bartonella henselae is occasionally associated with neurological dysfunction in people and some experimentally infected cats. the purpose of this study was to determine whether b henselae seroprevalence or titer magnitude varies among cats with neurological disease, cats with non-neurological diseases, and healthy cats while controlling for age and flea exposure. there was no difference in b henselae seroprevalence rates between cats with seizures and cats with other neurological diseases. cats ... | 2006 | 16949848 |
| [a case of hepatosplenic cat scratch disease]. | a 43-year-old man was admitted with idiopathic fever. abdominal ultrasonogram demonstrated multiple hypoechoic lesions in the spleen. abdominal ct scan showed multiple hypodense lesions in the liver and spleen. the patient had a cat in his house, and the presence of a very high serous antibody titer for bartonella henselae led to the diagnosis of hepatosplenic cat scratch disease. it is important to consider this disease in the differential diagnosis of idiopathic fever when multiple lesions are ... | 2006 | 16953102 |
| alpha1-proteinase inhibitor deficiency and bartonella infection in association with panniculitis, polyarthritis, and meningitis in a dog. | | 2006 | 16955834 |
| [hepatosplenic localization of cat scratch disease: two cases in immunocompetent adult patients]. | cat-scratch disease (csd) is a well-recognized benign cause of localized lymphadenopathy, which often recovers spontaneously. however systemic clinical presentations are described in immunodeficient adults (bacillary angiomatosis, bacillary splenitis) and are less common in immunocompetent ones. | 2006 | 16959382 |
| bartonella quintana prosthetic valve endocarditis detected by blood culture incubation beyond 10 days. | we describe the case of a 45-year-old man with mitral and aortic prosthetic valve replacement who presented with symptoms of subacute bacterial endocarditis. bartonella quintana was grown from blood after prolonged culture. the course of the disease was complicated by splenic infarction, glomerulonephritis resulting in progressive renal insufficiency, and cerebroventricular hemorrhage. notably, cardiac ultrasonography showed no extensive vegetations but a strand-like lesion. culture-positive b. ... | 2006 | 16962956 |
| somatostatin receptor scintigraphy in patients with cat-scratch disease. | somatostatin receptor scintigraphy images various neoplastic, granulomatous, and auto-immune diseases. cat-scratch disease in an infectious granulomatous disease usually affecting the lymphnodes. it is not known whether cat-scratch disease provides positive somatostatin receptor scintigrams. | 2006 | 16964341 |
| [cat scratch disease--course, diagnosis]. | cat scratch disease is an infection which often causes regional lymphadenopathy. bartenolloses present a growing health problem both in human and veterinary medicine. they may be etiological fevers of unknown etiology, endocarditis, pneumonia, meningitis. the mildest clinical form is the cat scratch disease which proceeds as a mild regional lymphadenopathy. it is caused by bartonellosis henselae. animals, especially cats, are the sourse of infections. lymphadenitis may remain for many weeks and ... | 2006 | 16964683 |
| rickettsial agents in egyptian ticks collected from domestic animals. | to assess the presence of rickettsial pathogens in ticks from egypt, we collected ticks from domestic and peridomestic animals between june 2002 and july 2003. dna extracts from 1019 ticks were tested, using pcr and sequencing, for anaplasma spp., bartonella spp., coxiella burnetii, ehrlichia spp., and rickettsia spp. ticks included: 29 argas persicus, 10 hyalomma anatolicum anatolicum, 55 hyalomma anatolicum excavatum, 174 hyalomma dromedarii, 2 hyalomma impeltatum, 3 hyalomma marginatum rufipe ... | 2006 | 17004028 |
| characterization of th1 activation by bartonella henselae stimulation in balb/c mice: inhibitory activities of interleukin-10 for the production of interferon-gamma in spleen cells. | this study was conducted to analyze cytokine production mechanisms in mice after bartonella henselae stimulation. balb/c mice were inoculated intraperitoneally with 3 x 10(6) colony forming units of b. henselae (houston-1 strain) twice at 10-day interval. spleen cells were harvested from the mice and stimulated with the organisms. following the stimulation, interferon-gamma (ifn-gamma) and interleukin-4 (il-4), il-10, il-12 and tumor necrosis factor-alpha (tnf-alpha) were measured in the culture ... | 2007 | 17005337 |
| bartonella quintana, lice, and molecular tools. | | 2006 | 17017209 |
| dynamics of the incw genetic backbone imply general trends in conjugative plasmid evolution. | plasmids cannot be understood as mere tools for genetic exchange: they are themselves subject to the forces of evolution. their genomic and phylogenetic features have been less studied in this respect. focusing on the incw incompatibility group, which includes the smallest known conjugative plasmids, we attempt to unveil some common trends in plasmid evolution. the functional modules of incw genetic backbone are described, with emphasis on their architecture and relationships to other plasmid gr ... | 2006 | 17026718 |
| bartonella infections: diagnostic and management issues. | bartonella species are emerging pathogens. renewed interest in this group of bacteria has been highlighted by the recent description of new species, which are pathogenic for humans (bartonella elizabethae and bartonella clarridgeae), and their association with an increasing number of clinical manifestations, the more prevalent being cat scratch disease, bacillary angiomatosis, and culture-negative endocarditis. | 1998 | 17033388 |
| molecular detection of rickettsia felis, rickettsia typhi and two genotypes closely related to bartonella elizabethae. | a total of 56 fleas were collected from mice, rats, and one hedgehog in national parks of mainland portugal and the madeira island. all fleas were tested for the presence of bacteria of the genera rickettsia and bartonella using pcr assays. in fleas from mainland portugal, we detected rickettsia felis in one archaeopsylla erinacei maura flea and in one ctenophtalmus sp. in five leptopsylla segnis fleas taken from rats in the madeira island, we identified rickettsia typhi. in addition, in four fl ... | 2006 | 17038702 |
| the reach of the genome signature in prokaryotes. | with the increased availability of sequenced genomes there have been several initiatives to infer evolutionary relationships by whole genome characteristics. one of these studies suggested good congruence between genome synteny, shared gene content, 16s ribosomal dna identity, codon usage and the genome signature in prokaryotes. here we rigorously test the phylogenetic signal of the genome signature, which consists of the genome-specific relative frequencies of dinucleotides, on 334 sequenced pr ... | 2006 | 17040564 |
| isolated hepatic involvement of cat scratch disease in immunocompetent adults: enhanced magnetic resonance imaging, pathological findings, and molecular analysis--two cases. | visceral involvement in absence of lymphadenopathy is a rare manifestation in cat scratch disease; hepatic granulomas are rare, representing 0.3% of systemic manifestations of cat scratch disease, and gallbladder extension is a singular case. the present article refers to 2 rare cases of visceral cat scratch disease in immunocompetent adults with hepatic granulomatous inflammation, caused by bartonella henselae infection, with gallbladder involvement in 1 case and no lymphadenopathy. histologica ... | 2006 | 17041206 |
| the identification of two protective dna vaccines from a panel of five plasmid constructs encoding brucella melitensis 16m genes. | five candidate genes from the brucella melitensis 16m genome were selected. eukaryotic expression plasmids encoding these antigens were constructed and expression was verified in vitro from transfected cos7 cells. each vaccine was assessed for protective efficacy in a balb/c mouse brucellosis infection model. from these experiments two protective dna vaccines were identified: p-omp25 and p-ialb. the omp25 antigen (bmei1249) has previously been studied in terms of brucella virulence, serodiagnosi ... | 2007 | 17049676 |
| analysis of bartonella adhesin a expression reveals differences between various b. henselae strains. | bartonella henselae causes cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis in humans. one of the best known pathogenicity factors of b. henselae is bartonella adhesin a (bada), which is modularly constructed, consisting of head, neck/stalk, and membrane anchor domains. bada is important for the adhesion of b. henselae to extracellular-matrix proteins and endothelial cells (ecs). in this study, we analyzed different b. henselae strains for ba ... | 2007 | 17060468 |
| lymph node biopsy specimens and diagnosis of cat-scratch disease. | we report microbiologic analysis of 786 lymph node biopsy specimens from patients with suspected cat-scratch disease (csd). the specimens were examined by standard, cell culture, and molecular methods. infectious agents were found in samples from 391 (49.7%) of 786 patients. the most commonly identified infectious agent was bartonella henselae (245 patients, 31.2%), the agent of csd. mycobacteriosis was diagnosed in 54 patients (6.9%) by culture and retrospectively confirmed by using a specific ... | 2006 | 17073081 |
| isolation of bartonella quintana from a woman and a cat following putative bite transmission. | we report here the detection of bartonella quintana, after putative bite transmission, in pre-enrichment blood cultures from a woman and from two feral barn cats. prospective molecular epidemiological studies are necessary to characterize the risk of human bartonella quintana infection following cat bites. | 2007 | 17093037 |
| [wild small mammals are the reservoir hosts of the bartonella genus bacteria in the south of moscow region]. | a total of 103 blood samples collected from wild small mammals captured in the prioksko-terrasny reserve on the south of moscow region were studied to determine the bartonellae prevalence. the examined species were the yellow-necked mice apodemus flavicollis (35 samples), the european wood mouse apodemus uralensis (10 samples), the bank vole clethrionomys glareolus (51 samples), the house mouse mus musculus (3 samples), the common vole microtus arvalis (2 samples), and the shrew sorex araneus (2 ... | 2006 | 17094651 |
| contrasting dynamics of bartonella spp. in cyclic field vole populations: the impact of vector and host dynamics. | many zoonotic disease agents are transmitted between hosts by arthropod vectors, including fleas, but few empirical studies of host-vector-microparasite dynamics have investigated the relative importance of hosts and vectors. this study investigates the dynamics of 4 closely related bartonella species and their flea vectors in cyclic populations of field voles (microtus agrestis) over 3 years. the probability of flea infestation was positively related to field vole density 12 months previously i ... | 2007 | 17096870 |
| immunohistochemical study of lymph nodes in patients with cat scratch disease. | bartonella henselaeis the causative agent of cat scratch disease (csd), manifesting as fever and acute regional lymphadenopathy. although serologic testing is the reference method for diagnosis, successful use of immunohistochemical (ihc) stain of regional lymph nodes for the diagnosis of csd has been reported. to determine the characterization and diagnostic potential of ihc in lymphadenopathy of csd, lymph nodes were excised from patients with suspected csd for further evaluation. | 2006 | 17098692 |
| indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following listeria monocytogenes infection. | control of pathogens by formation of abscesses and granulomas is a major strategy of the innate immune system, especially when effector mechanisms of adaptive immunity are insufficient. we show in human listeriosis that dcs expressing indoleamine 2,3-dioxygenase (ido), together with macrophages, are major cellular components of suppurative granulomas in vivo. induction of ido by dcs is a cell-autonomous response to listeria monocytogenes infection and was also observed in other granulomatous inf ... | 2006 | 17111046 |
| bartonella henselae endocarditis in a child. | 14-year-old white male with a past medical history of congenital bicuspid aortic valve, streptococcus viridans endocarditis, and pulmonary valve homograft presented with culture-negative endocarditis. molecular studies identified the causative organism as bartonella henselae and subsequent serologic studies supported this diagnosis. this rare cause of endocarditis may be under recognized in children. bartonella henselae endocarditis should be considered in all children with culture-negative endo ... | 2006 | 17111290 |
| infective endocarditis due to bartonella spp. and coxiella burnetii: experience at a cardiology hospital in sao paulo, brazil. | bartonella spp. and coxiella burnetii are recognized as causative agents of blood culture-negative endocarditis (bcne) in humans and there are no studies of their occurrences in brazil. the purpose of this study is to investigate bartonella spp. and c. burnetii as a causative agent of culture-negative endocarditis patients at a cardiology hospital in são paulo, brazil. from january 2004 to december 2004 patients with a diagnosis of endocarditis at our institute were identified and recorded prosp ... | 2006 | 17114712 |
| arthropod-borne diseases in homeless. | homeless people are particularly exposed to ectoparasite. the living conditions and the crowded shelters provide ideal conditions for the spread of lice, fleas, ticks, and mites. body lice have long been recognized as human parasites and although typically prevalent in rural communities in upland areas of countries close to the equator, it is now increasingly encountered in developed countries especially in homeless people or inner city economically deprived population. fleas are widespread but ... | 2006 | 17114713 |
| prevalence of rickettsia felis-like and bartonella spp. in ctenocephalides felis and ctenocephalides canis from la rioja (northern spain). | our aim was to determine the presence of rickettsia spp. and bartonella spp. in ctenocephalides felis and ctenocephalides canis from la rioja (spain). a total of 88 specimens were tested by polymerase chain reaction (pcr) using glta and ompb genes as targets for rickettsia spp., and 16s rrna and ribc genes for bartonella spp. rickettsia felis-like (28.4%), bartonella clarridgeiae (6.8%), and bartonella henselae (3.4%) were detected in ctenocephalides spp. other bartonella sp. different from b. c ... | 2006 | 17114721 |
| population survey of egyptian arthropods for rickettsial agents. | between june 2002 and july 2003, 987 fleas, representing four species, and 1019 ticks, representing one argasid and eight ixodid species, were collected from egyptian animals. these arthropods were tested for rickettsial agents using polymerase chain reaction. dnas from anaplasma and ehrlichia spp. were detected in 13 ticks. previously undescribed bartonella spp. were detected in 21 fleas. coxiella burnetii was detected in two fleas and 20 ticks. rickettsia typhi was detected in 27 fleas from 10 ... | 2006 | 17114742 |
| bartonella infection in domestic cats and wild felids. | bartonella are vector-borne, fastidious gram-negative bacteria causing persistent bacteremia in their reservoir hosts. felids represent a major reservoir for several bartonella species. domestic cats are the main reservoir of b. henselae, the agent of cat-scratch disease. prevalence of infection is highest in warm and humid climates that are optimal for the survival of cat fleas, as fleas are essential for the transmission of the infection. flea feces are the likely infectious substrate. prevale ... | 2006 | 17114749 |
| corpuscular antigenic microarray for the serodiagnosis of blood culture-negative endocarditis. | blood culture-negative endocarditis is due to fastidious bacteria, including coxiella burnetii and bartonella spp. diagnosis of such infection relies on serology and microimmunofluorescence is therefore the reference method. we developed a multiplex serology test featuring automatic incubation and reading and incorporating internal controls. preliminary results indicate that this new serologic test is valuable for the rapid, automated serological diagnosis of blood culture-negative endocarditis. | 2006 | 17114786 |
| a translocated bacterial protein protects vascular endothelial cells from apoptosis. | the modulation of host cell apoptosis by bacterial pathogens is of critical importance for the outcome of the infection process. the capacity of bartonella henselae and b. quintana to cause vascular tumor formation in immunocompromised patients is linked to the inhibition of vascular endothelial cell (ec) apoptosis. here, we show that translocation of bepa, a type iv secretion (t4s) substrate, is necessary and sufficient to inhibit ec apoptosis. ectopic expression in ecs allowed mapping of the a ... | 2006 | 17121462 |
| [endocarditis due to bartonella spp. three new clinical cases and spanish literature review]. | | 2006 | 17125688 |
| [prevalence of bartonella henselae antibodies in chilean children, adolescents and veterinary workers]. | bartonella henselae is the causative agent of cat-scratch disease. | 2006 | 17130969 |
| transient paresis associated with cat-scratch disease: case report and literature review of vertebral osteomyelitis caused by bartonella henselae. | cat-scratch disease (csd) rarely presents as vertebral osteomyelitis. we describe a case with paresis of the arm with total recovery after antibiotic and neurosurgical therapy. we reviewed 20 other cases of csd vertebral osteomyelitis in the literature. this diagnosis should be considered in patients with systemic symptoms, back pain, and cat contact. the prognosis is generally good. | 2006 | 17133166 |
| an unusual outcome in a child with hepatosplenic cat-scratch disease. | typical cat-scratch disease (bartonella henselae infection) in an immunocompetent child is usually associated with a history of scratch, bite or intimate contact with a cat. most patients develop a non-tender papule in the scratch line after three to ten days. this may persist for only a few days or as long as two to three weeks. during the next two weeks or more, regional lymph nodes that drain the area gradually enlarge and then slowly resolve in more than 10% of patients. the nodes develop ov ... | 2006 | 17136337 |
| [bacterial zoonoses: emerging concepts]. | bacterial zoonoses are evolving with changes in society, climate and lifestyles. a hierarchy of non food-borne zoonoses was recently proposed in france, and includes characteristics such as severity criteria and bioterrorism potential. the creation of specific networks and reference centers has provided the means to monitor the emergence (or re-emergence) of zoonoses such as brucellosis and q fever. molecular tools have facilitated the detection of bacteria that are transmitted by arthropod vect ... | 2006 | 17140097 |
| bone infection in cat-scratch disease: a review of the literature. | to describe the main features of bone infection associated with cat-scratch disease (csd). | 2007 | 17140668 |
| [bartonella henselae as a cause of optical nerve neuritis]. | bartonella henselae is included into the group of gram-negative bacteria that can cause not so rare disease known as cat-scratch disease (csd). this disease is characterized by the specific general symptoms, and the complications in the eyes can be manifested in the form of neuroretinitis, follicular conjunctivitis and focal chorioretinitis. in this paper clinical and epidemiological characteristics of a patient with ophthalmologic complications caused by bartonella henselae are described. we in ... | 2006 | 17144434 |
| bone marrow and skin granulomatosis in a patient with bartonella infection. | this report describes a case of granulomatous inflammation, involving the bone marrow and skin, due to bartonella infection in an immunocompetent patient. the clinical presentation included prolonged fever, pancytopenia, rash and hepatitis. bartonella infection should thus be added to the growing list of entities that produce marrow granulomas and fever. | 2007 | 17172528 |
| effect of high-dose methyl-prednisolone on brainstem encephalopathy and basal ganglia impairment complicating cat scratch disease. | cat scratch disease (csd) is a zoonotic illness caused by the gram negative bacillus bartonella henselae characterized by a small skin lesion at the site of a bite, lick or scratch by a cat, commonly followed by regional lymphadenopathy 1 or 2 weeks later. we report herein on severe neurological complications of csd combining brainstem encephalopathy and basal ganglia impairment. this 12-year-old female acutely presented to a local hospital with profound coma and a prolonged tonic posturing of e ... | 2007 | 17174500 |
| an unusual cutaneous presentation of cat-scratch disease. | | 2007 | 17176268 |
| [cat-scratch disease. review of eight adult patients hospitalized for fever or adenopathy]. | cat-scratch disease is common among children. among adults the disease is less often considered in the differential diagnosis of enlarged lymph nodes and fever. | 2006 | 17186093 |
| pyogenic splenic abscess in an infant with serological evidence of cat scratch disease. | | 2007 | 17186270 |
| diversity of bartonella genotypes in richardson's ground squirrel populations. | the diversity and dynamics of bartonella genotypes found in wild richardson's ground squirrels (rgs), spermophilus richardsonii were monitored at multiple sites in saskatchewan, canada from 2002 to 2004. based on sequence analysis of a portion of the bartonella citrate synthase (glta) gene, four different genotypes were detected in 233 isolates from 176 animals. the majority (87%) of sequences were identified as genotype h, with genotypes i, j, and k accounting for 8%, 4%, and 1% of sequences, r ... | 2006 | 17187575 |