Publications

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the genetic toxicology of phenoxy acids other than 2,4,5-t. 1998107443
cerebrospinal fluid-, blood-, and ascitis-catecholamines in hepatic cirrhosis.the consideration of the extensive innervation of liver parenchyma, together with data relating to the degradation of catecholamines in the liver and the importance of hepatic vascular process in hepatic cirrhosis, prompted us to investigate the behaviour of catecholamines in this condition. the following parameters were measured in cerebrospinal fluid (csf), blood and ascitis fluid: total catecholamines, adrenaline and noradrenaline. during hepatic cirrhosis, total catecholamines level in blood ...1998106413
thyroid hormone binding protein in chronic active hepatitis. 1998106280
[clinical significance of lipid metabolic indices in diabetes mellitus in children]. 199898917
morphologic effects of thio-tepa on mammalian urothelium. changes in abnormal cells.morphologic changes induced by thio-tepa were examined in animals with chemically induced neoplasms. both toxic and metabolic effects were documented. degeneration, vacuolization and increased exfoliation (toxic) were most prominent, occurred within 48 hours of exposure, and tended to subside after removal of the drug. nuclear changes (metabolic) were rare and occurred late. neither toxic nor metabolic effects were specific for thio-tepa: both could be detected in control animals receiving salin ...1998104512
the use of titanium (iv) oxide for the immobilisation of carbohydrate-directed enzymes.the use of particles of porous titanium (iv) oxide as a suitable matrix for enzyme immobilisation has been investigated with dextranase. treatment of the particles with enzyme in the presence and absence of ammonium ions showed that the presence of ammonia induced a greater coupling of protein, whereas a greater retention of enzyme specific activity was achieved in the absence of ammonia. properties of the immobilised enzyme include a ph-dependence and reversibility of the coupling between enzym ...199820228
peripheral nerve pathway to the ciliary muscle. 1998108120
the location of 5s rna genes in lampbrush polytene chromosomes from drosophila. 1998108119
effects of apomorphine upon local cerebral blood flow.the effects of apomorphine (0.1 mg/kg) upon local cerebral blood flow were examined in anaesthetized baboons. proportionately similar increases in local cerebral blood flow were observed following apomorphine in the caudate nucleus (40%), cerebral cortex (38%) and cerebellar cortex (26%), despite the marked differences in the density of the dopaminergic innervation to these structures.1998108114
infusion hepatotomography for evaluation of obstructive jaundice.total body opacification with high doses of a urographic contrast agent demonstrated dilated intrahepatic biliary ducts as branching or rounded lucencies in all of 18 patients with obstructive jaundice. dilated extrahepatic ducts were seen as tubular lucencies in 11 of 16 patients with distal common bile duct obstruction. in seven patients with nonobstructive jaundice and in a control group of 25, the biliary ducts were either normal or not seen. gallbladder size was also evaluated. the site of ...1998105580
[infection in biliary surgery. per and post-operative bacteriological study (author's transl)]. 1998107009
evaluation of nutritional indices as prognostic indicators in the cancer patient.the nutritional and immunological status of 140 malnourished cancer patients who were to receive intravenous hyperalimentation (ivh) were evaluated prior to treatment with ivh and chemotherapy (cmx), surgery or radiation therapy (xrt). subsequently, these indices were correlated with responses to treatment. cell-mediated immunocompetent (cmi+) patients (41%) had lost an average weight of 10 +/- 2.2 lbs., while cell-mediated immunoincompetent (cmi-) patients (59%) had lost an average weight of 31 ...1998106954
radiation in multidisciplinary treatment of children with malignant ovarian tumors.thirteen girls with malignant ovarian tumors treated at memorial hospital from august 1971 through october 1975 with extensive surgery, multi-drug chemotherapy (t-2 protocol) and postoperative radiation were reviewed. the plan of radiation was to deliver 3,000 rads to the whole abdomen and boost the para-aortic and pelvic area with 1,500 rads in five to six weeks. in only two patients was the radiation conducted as planned. in others the treatment was either interrupted or discontinued due to co ...1998106952
therapeutic drug monitoring for antidepressants: efficacy, safety, and cost effectiveness.therapeutic drug monitoring (tdm) of tricyclic antidepressants (tcas) is a cost-effective tool to increase efficacy and safety in patients suffering from major depressive illness. the concentration:antidepressant response relationships of nortriptyline, desipramine, and amitriptyline conform to a curvilinear relationship between concentration:antidepressant response; whereas, imipramine conforms to a linear relationship. besides improving efficacy, tdm identifies the subset of patients who are a ...19981904862
[pancreatic carcinoma on endoscopic retrograde pancreatico-cholangiogram (author's transl)].the pancreaticographic appearances of carcinoma of the pancreas have been divided into two types: 1. canalicular carcinoma arising from the duct system. if arising from the main pancreatic duct, it occludes this, or causes displacement or deformity of its branches in the immediate neighbourhood. if arising from branches, it causes cystic ectasia of the minor ducts; these appear fragmented and deformed while there is stenosis and displacement of the main duct. simultaneous origin from the main an ...1998124684
psros and cost containment: a cautious perspective. 1998121393
[detection of coronary artery spasm by the methylergometrin test. technic. results. indications].methylergometrine (methergin) was given intravenously (0.4 mg) to 118 patients undergoing coronary arteriography. the electrocardiogramme and intraaortic pressure was continuously monitored whilst coronary arteriography was performed, 1,3, and 5 minutes after the injection of the ergot alkaloid. the test was positive if: 1) coronary spasm was observed; 2) if st segment elevation was recorded with or without pain. positive tests were obtained in 13 out of 14 patients with prinzmetal angina. the t ...1998107890
orojejunal feeding in low birthweight infants. 1998107866
phase changes of cardiolipin vesicles mediated by divalent cations.small unilamellar vesicles were prepared from cardiolipin and produced the hexagonal ii phase when dialyzed against cacl2 or mgcl2. upon removal of the cation by dialysis against edta large unilamellar vesicles were formed. the events of the transition from the lamellar to hexagonal phase and back to the lamellar phase are described.1998106890
rising health care costs: a schism between medicine and business? 199997049
suction drainage after stripping of long saphenous veins. 199989589
the use of relaxation and desensitisation techniques in eliminating a sleep problem.this study describes the treatment of a 16-year-old youth unable to sleep, failing to respond to sleeping pills, who on a programme of relaxation and desensitisation in six weeks was able to control his sleeping patterns. on followup four months, six months and twelve months later this ability had been maintained.199924192
[microspectrophotometric study of biogenic amines in ganglions of the central nervous system of crepidula fornicata (phil.)].the fluorescent products formed from biogenic amines treated with formaldehyde according to the method of falck and owman have been studied in the brain of crepidula fornicata. the microspectrophotometric analysis of cellular indolamines shows excitation emission maxima at 385--525 nm (serotonine) and catecholamine at 410--475 nm upon hcl treatment catecholamine products show a shift of the excitation peak from 410 to 370 nm (dopamine).1999103642
diminished cellular immunity due to impaired nutrition in oesophageal carcinoma.the nutritional status of 15 negro patients suffering from unresectable carcinoma of the midthoracic oesophagus was evaluated before and after palliative pulsion intubation. all were shown to be in negative nitrogen balance and to have a compromised non-specific cellular immune response. correction of protein-calorie malnutrition and the achievement of positive nitrogen balance were associated with an increase in absolute lymphocyte and t lymphocyte numbers and a significant increase in lymphocy ...199996903
[proton beam treatment in the neurosurgical field]. 199996847
simultaneous treatment of toxic diffuse goiter with i-131 and antithyroid drugs: a prospective study.we report a prospective study to avaluate the effect of antithyroid drugs containing the sulfhydryl radical on the outcome of i-131 (rai) therapy. twenty-four male patients withe toxic diffuse goiter were assigned randomly into tow treatment groups: group a received rai treatment while on antighyroid drugs after attainment of euthyroidism; group b received no antithyroid drugs before, or when, rai was given. patients in each group received a dose of rai calculated to deliver approximately 5000 r ...199994089
[monitoring the course of malignant neoplasms of the genital organs in women by means of determination of blood serum level of fucose, sialic acid, cea and afp]. 199994024
the use of behavioral checklists to assess physical examination skills. 199917754
substrate specificity of hexosaminidase a isolated from the liver of a patient with a rare form (ab variant) of infantile gm2 gangliosidosis and control tissues. 199996668
acute acalculous cholecystitis: a complication of hyperalimentation.in a 5 year period, eight patients in whom acute acalculous cholecystitis developed during intravenous hyperalimentation are reviewed with emphasis on factors contributing to pathogenesis. gallbladder distention, biliary stasis, and bile inspissation, thought to be important in the pathogenesis of this disease, are enhanced with the use of hyperalimentation, and this potential complication is being seen with increasing frequency in seriously ill or injured patients who are being fed parenterally ...1999116561
analysis of rna-binding proteins of cryptobiotic gastrula of artemia saline [proceedings]. 199993910
relaxation of striated muscle by low concentrations of atp [proceedings]. 199993891
role of nonspecific and specific suppressor factors in immunity. 199993866
retention of dr-specific memory in primed lymphocytes grown in pha-conditioned media. 199993819
ear-lobe crease. 199984982
[mechanism of antibiotic action]. 199993768
[retinal neovascularization: topological, morphological and hemodynamic features (author's transl)]. 199991317
catecholamines and hyperthyroidism. 199922414
haloperidol and lithium blocking of the mood response to intravenous methylphenidate.the euthymic manic-d-pressive patients with therapeutic plasma lithium levels were each given two i.f. infusions of 30 mg of methylphenidate. the infusions were separated by at least 3 days. before one infusion each patient was given 5 mg of haloperidol i.v. and before the other infusion each was given an identical volume of saline. a psychiatric observer was blind to the nature of the pretreatment and the order of pretreatment was randomized. saline pretreated patients showed marked activation ...199996473
[diagnosis of malignant neoplasms by studying the changes in the concentration of fetal hemoglobin, hemoglobin a2 and carbonic anhydrases b and c. an application of discriminating function].this publication proposes the utilization of an analytical discriminatory method in the diagnosis of malignant neoplasia. the multiple variable technique of analysis is suggested employing the quantification of the hbf, hba2, acb and acc. this has already been demonstrated in a previous study which suffered from quantifiable variations important in neoplastic disease. the confidence of the procedure has been proven when applied to 198 known cases, having classified them adequately 94 per cent of ...199996435
atrial repolarization: its role in st elevation.in four patients, ectopic supraventricular rhythm (or beats) with cephalad anomalous atrial activation and, generally, a short pr, were always associated with an st elevation in the leads with a negative p wave. an inverted ta wave appears to be responsible for the st elevation.199989183
hyperthyroidism in juvenile diabetes mellitus.three cases of hyperthyroidism occurring in juvenile patients with diabetes mellitus are presented. the presence of hyperthyroidism should be suspected in patients with diabetes mellitus when goiters develop and when there is unexplained weight loss, tachycardia, tremors, unexplained increases in insulin requirement, or instability of the diabetes with a tendency toward development of ketosis and/or ketoacidosis.199996415
progress report on an evaluation of speech therapy for aphasia. 199993486
the use of the voiscope in improving the speech of profoundly deaf children. 199993485
[availability of the measurement of plasma beta-thromboglobulin (beta-tg) for cerebrovascular diseases (author's transl)]. 199993482
unmasking of fetal determinants on adult bone marrow cells. 199991109
a neuropathologic study of whipple's disease.a patient with whipple's disease developed massive and irreversible cns involvement after a drug-induced intestinal remission. the multifocal brain lesions were apparent grossly with the heaviest concentration being noted in rhinencephalon, diencephalon, and mesencephalon. this patient exhibited progressive neurologic deterioration, although viable organisms could not be identified in the brain at autopsy. astrocytes, pericytes, and choroid plexus cells attempted to dispose of the organism, in a ...199993389
retinol-binding protein in malnutrition. 199990984
failure of anti-d immunoglobulin to remove fetal red cells from maternal circulation.a rhesus negative female was found post delivery to have circulating cells of fetal origin. the neonate was typed as d-positive. in spite of more than conventionally adequate doses of anti-d immunoglobulin given to the mother, the fetal cell count in the maternal circulation remained unchanged. further investigation showed the fetus to be a du variant and to exhibit a diminished reaction with the batch of anti-d immunoglobulin used.2000111422
[cardiac rhythm disorders following nitroglycerin]. 2000111414
quantitative comparison between xenodiagnosis and haemoculture in the detection of trypanosoma (schizotrypanum) cruzi in experimental and natural chronic infections. 200097813
[recommendations for the storage of serum absorbed on filter paper under rural conditions, for the diagnosis of chagas' infection with immunofluorescent test]. 200097768
deafness due to hypervitaminosis d. 200087663
[decompensated juvenile diabetes mellitus simulating acute abdomen]. 2000138884
cutaneous manifestations of acute carbon monoxide poisoning.a patient with acute carbon monoxide poisoning due to leakage of gas from the exhaust system in his automobile noted edema and blister formation over large areas of the skin of one half of his body. rhabdomyolysis, acute but transient renal insufficiency, and hemolytic anemia developed subsequently.200092389
comment on "the single distribution theory of alcohol consumption". 2000314022
a vertical couch extender. 2000110741
[do you still consider anticoagulant therapy for the prevention of coronary infarct a necessary indication today?]. 2000101731
esophagogastrectomy for carcinoma of the middle third of the esophagus.elective esophagogastrectomy and reconstruction by esophagogastrostomy were performed on 55 patients with malignant tumors of the midesophagus, despite invasion of contiguous structures in 60% and regional lymph node involvement in 75%. the operations were invariably palliative. two patients died within thirty days of operation. dysphagia was relieved and oral alimentation resumed in the other 53. twenty-nine patients who had experienced painful swallowing and 16 who had vomiting obtained relief ...200092220
[nitrogen balances in very premature newborns in the course of parenteral nutrition (author's transl)].nitrogen balance studies were performed in the course of parenteral nutrition during the first 5 days of life in 2 groups of premature newborns (i. group: 7 prematures, b.w. m = 1295g; ii. group: 7 prematures, b.w. m = 1447g). glucose and fat emulsion were administered intravenously in children of the first group, in the second one l- aminoacids (250 mg n/kg body weight/24 hrs.) were added. in comparison with the first group nitrogen retention of 77 to 170 mg/kg body weight/24 hrs. was reached, ...2000101957
elongation of metacarpal and phalangeal bones using a distraction method by children and juveniles with inborn developmental anomalies of the hand. 200092126
[studies on cardiac principle in aconite roots. i. isolation and structural determination of higenamine (author's transl)]. 200034017
isolation and surface labeling of murine polymorphonuclear neutrophils.methods for the induction of an exudate of polymorphonuclear neutrophilic leukocytes (pmn) in the peritoneal cavity of c57bl, balb/c, sjl and cba mice were analysed. peritoneal exudates in male mice were highly enriched for pmn (80-90%) three hours after a single injection of calcium caseinate whereas eosinophils comprised less than 1% of the exudate population. female mice were a less satisfactory source of pmn because the proportion of eosinophilis in the exudate was variable. purification of ...2000313932
eosinophilic globules in spitz's nevi. new findings and a diagnostic sign.dull pink globules were found within the epidermis in 65% of junctional, 75% of compound, and 25% of intradermal types of spitz's nevi (the nevi of large spindle and/or epithelioid cells). these globules were pas-positive, diastase-resistant and also were positive with the trichrome stain. similar-appearing eosinophilic globules were noted in the epidermis in only 2% of malignant melanomas and in but 0.9% of ordinary melanocytic nevi. the globules in malignant melanomas and in ordinary melanocyt ...200094511
loin pain/haematuria syndrome. 200086752
[increased demethylation of aminopyrine under long-term treatment with anticonvulsive drugs (author's transl)].demethylation of aminopyrine was measured in 25 healthy controls and 19 epileptics on long-term treatment with anticonvulsants by the 14c-aminopyrine breath test. compared to controls epileptics exhibited increased cumulative 14co2-exhalation rates (88.7% at 30 min, 62.6% at 2 h and 24.8% at 8h) following ingestion of 2 mu ci 14c-aminopyrine. the results suggest that long-term treatment with antiepileptic drugs results in increased demethylating function of the liver which can be easily detected ...200097469
alcohol and the blood. 200089860
the typical dream: case studies. 20004347834
renal responses of the recumbent nonhuman primate to total body water immersion. 2000111262
phencyclidine and ketamine intoxication: a study of four populations of recreational users. 2000101865
premature opening of the aortic valve: an index of highly advanced aortic regurgitation. 200097320
tiquinamide. 200091921
visual averaged evoked responses in psychiatric patients. relationship to levels of 5-hydroxy-indoleacetic acid, homovanilic acid and tryptophan in cerebrospinal fluid. 200094355
first scribbles: the emergence of an ego function. 200094332
steroids in asthma. 200091910
dangerous pathogens and the h.s.e. 200091867
determination of the functional affinity of igg1 and igg4 antibodies to tetanus toxoid by isotype-specific solid-phase assays.two solid-phase assays have been used to measure the affinity of igg1 and igg4 antibodies to tetanus toxoid (tt) in whole sera. in the first assay, low affinity antibodies were selectively inhibited from binding to solid-phase antigen by a mild chaotropic agent and in the second assay, high affinity antibodies were preferentially inhibited from binding by low concentrations of free antigen. results from both assays suggest that igg4 antibodies to tt are of lower functional affinity than igg1 ant ...20002448383
richard b. capps 1906-1976. 2000382586
ld typing and the lack of involvement of sd antigens in the priming process.peripheral blood lymphocytes with known hla-sd were typed for ld determinants using a panel of primed cells prepared from sd identical lymphocytes. then these lymphocytes (with known sd and ld) were primed by x-irradiated cells from the same sd and ld group and their secondary reactions were evaluated. disparity in sd antigens of responder and stimulator cells did not produce primed cells and lymphocytes were primed only for ld differences. this finding allows ld typing using primed cells from a ...200165020
[changes in the dental pulp during the preparation of artificial cavities (an electron microscopic study)]. 200198864
behaviour of alpha1-antitrypsin in lung cancer. 200198836
protection of primate lung from stored-blood perfusion by peptidase inhibition and target membrane stabilization.microaggregate filtration and separation of the cellular components of stored autologous blood have not changed the functional and morphological damage in primate lungs from stored-blood perfusion. pharmacologic prevention of these "shock lung" changes was attempted with trasylol and with methylprednisolone pretreatment. in an in situ primate lung perfusion model, fresh and stored blood was perfused in untreated baboons and in groups of seven animals each pretreated with trasylol or methylpredni ...200195551
nucleic acids quantitation in polyacrylamide disc gels with a modified double beam spectrophotometer.quantitation of rna and protein bands separated in polyacrylamide disc gel electrophoresis is time consuming and not reliable when performed after staining processes. the best theoretical approach is the use of absorption spectra of the samples. the present paper reports the construction of an efficient and inexpensive adapter to perform direct scanning of 100 mm gels in a unicam sp-800 double beam spectrophotometer. conditions for gel casting and electrophoresis were established for rna. a line ...200195523
[acute mercury poisoning in children (author's transl)]. 200195513
severe skin pain after puva treatment.severe skin pain lasting one or two months occurred in 8 of 210 patients treated with puva. the pain started 4--8 weeks after the initial dose, mostly about one week after discontinuation of the treatment. it was a prickling, burning pain, usually coming in bouts and confined to limited areas "deep under the skin". in some respects the pain was related to itching, but the patients could easily distinguish between the two sensations. a variety of drugs was tried, but none had any noteworthy effec ...200193376
[palliative therapy of stenosing reflux esophagitis]. 200193354
fluorescent y-bodies in interphase nuclei: medicolegal aspects of false negative males. 200161152
a protein-glucan intermediate during paramylon synthesis.a sodium deoxycholate extract containing glucosyltransferase activity was obtained from a particulate preparation from euglena gracilis. it transferred glucose from udp-[14c]glucose into material that was precipitated by trichloroacetic acid. this material released beta-(1 leads to 3)-glucan oligosaccharides into solution on incubation with weak acid, weak alkali and beta-(1 leads to 3)-glucosidase. the products of the incubation of the deoxycholate extract with udp-[14c]glucose were analysed by ...2001100105
complications associated with aphakic contact lenses.complications associated with rigid contact lenses are more frequent in aphakia. the limited dexterity of older patients not only may prove an insurmountable barrier to the mastery of daily contact lens insertion and removal, but also may produce significant direct eye trauma, its seriousness determined by the integrity of the cataract wound. since prolonged wear of aphakic contact lenses is the rule rather than the exception, the risk of irreversible corneal changes such as vascularization and ...200193260
consistency of autoradiographic dna repair in cells treated "in vitro" with n-diazoacetylglycine amide. a preliminary approach to quantitate the absolute amount of dna repair. 200198772
[changes in physicochemical parameters and coagulation factors in hemodilution with dextran of molecular weight 60,000].in 18 subjects undergoing aorto-bifemoral by-pass, pre-operative isovalaemic hemodilution was carried out (using a dextran of molecular weight 60,000) at the same time as venous section of a mean value of 1087 ml reducing the hematocrit to 0.30. the following were studied before, immediately after and 24 hours after hemodilution: blood viscosity (at variable shearing rates), oncotic pressure, sedimentation rate, clotting factors, plasma electrolytes. these results showed that at the end of hemod ...200195471
anorectal cancer: electrocoagulation and irradiation treatment. 200195464
maternal influence upon the v-type gene position effect in drosophila melanogaster. 200198705
[concealed a-v functional extrasystole]. 200195404
cost of medical care. 200199526
[choroidal neovascularization]. 200195334
[medical management of tachycardias (author's transl)].guidelines for a step-wise plan of treatment of tachycardias have been compiled based on clinical empirical experience and with the aid of surface electrocardiograms, intracardial electrograms and stimulation techniques. the plan is primarily with the aid of surface electrocardiograms, intracardial electrograms and stimulation techniques. the plan is primarily oriented with respect to the antiarrhythmic efficacy, the adverse reactions and the practicability of the respective agents. any type of ...200193075
[palliative non-surgical bile duct drainage]. 200193044
health education as freeing. 200198497
flashbacks: ventricular fibrillation part i. 200195318
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