| cervical spine spondylodiscitis mimicking teardrop fracture. | pyogenic spondylodiscitis can have nonspecific clinical and imaging presentations. in this report, we describe a case of pyogenic spondylodisicits of cervical spine mimicking teardrop fracture on radiography. subsequent ct-guided biopsy helped identify the correct diagnosis and the responsible pathogen, staphylococcus aureus. | 2011 | 27307887 |
| incidence of community-associated methicillin-resistant staphylococcus aureus infections in a regional hospital. | since the early 2000s, the incidence of methicillin-resistant staphylococcus aureus (mrsa) infections among the community of people lacking known healthcare risk factors has increased. this mrsa infection is referred to as community-associated mrsa (ca-mrsa) infection and is distinct from hospital-associated mrsa (ha-mrsa) infection, which occurs among people with known healthcare risk factors. understanding the epidemiology of ca-mrsa infections is critical; however, this has not been investiga ... | 2011 | 25648247 |
| culture-positive endophthalmitis 6 hours after intravitreal antibiotics. | the purpose of this study was to report culture-positive endophthalmitis after intravitreal antibiotic injection and initial culture-negative tap. | 2011 | 25389673 |
| subretinal abscess after strabismus surgery: case report and literature review. | the purpose of this study is to describe the first reported case of a subretinal abscess after strabismus surgery and the successful treatment with vitrectomy, intravitreal antibiotics, and cryotherapy. | 2011 | 25389671 |
| nasal carriage of staphylococcus aureus in physician assistant students: initial prevalence and transmission during clinical rotations. | this study evaluated physician assistant (pa) students for nasal carriage of staphylococcus aureus (prerotations) and then again just prior to graduation. it also attempted to correlate initial and subsequent sample results with subject-specific survey data relating to students' general medical, social, behavioral, and geographical situations. | 2011 | 25137781 |
| in vitro synergy of biochanin a and ciprofloxacin against clinical isolates of staphylococcus aureus. | many clinical isolates of staphylococcus aureus (s. aureus) are resistant to numerous antimicrobials, including the fluoroquinolones (fqs). flavonoids such as biochanin a (bca) are compounds that are naturally present in fruits, vegetables, and plant-derived beverages. the goal of this investigation was to study the possible synergy between the antimicrobial agents bca and ciprofloxacin (cpfx) when used in combination; cpfx was chosen as a representative fq compound. we used s. aureus strain atc ... | 2011 | 25134769 |
| the essential oils activity of eucalyptus polycarpa, e. largiflorence, e. malliodora and e. camaldulensis on staphylococcus aureus. | because of its resistance to antibiotics, staphylococcus aureus causes many of problems in hospital and society. as one of the main reasons of clinical infections it can cause to serious surgical and cutaneous infections and pneumonia. the inhibitory effect of the essential oils include; eucalyptus largiflorence, e. camaldulensis, e. malliodora and e. polycarpa as a natural and herbal antimicrobial substances on staphylococcus aureus atcc 25923 and other antibiotic resistant series separated fro ... | 2011 | 24363679 |
| development and validation of a microbiological agar assay for determination of orbifloxacin in pharmaceutical preparations. | orbifloxacin is a fluoroquinolone with broad-spectrum antimicrobial activity, and belongs to the third generation of quinolones. regarding the quality control of medicines, a validated microbiological assay for determination of orbifloxacin in pharmaceutical formulations has not as yet been reported. for this purpose, this paper reports the development and validation of a simple, sensitive, accurate and reproducible agar diffusion method to quantify orbifloxacin in tablet formulations. the assay ... | 2011 | 24310597 |
| [mediastinitis]. | mediastinitis is defined as acute or chronic inflammation of the mediastinal structures and generally has a low incidence. the most frequent acute cause is sternotomy following cardiac revascularization surgery with both internal mammary arteries, with an incidence of 0.4% to 5% and a mortality of 16.5% to 47%. the most frequent vector is staphylococcus aureus. esophageal perforation, usually iatrogenic, is the second most frequent cause of acute mediastinitis, produced by common oropharyngeal f ... | 2011 | 23351519 |
| a comparative study between the antibacterial effect of nisin and nisin-loaded chitosan/alginate nanoparticles on the growth of staphylococcus aureus in raw and pasteurized milk samples. | the aim of this study was to evaluate the antibacterial effect of nisin-loaded chitosan/alginate nanoparticles as a novel antibacterial delivery vehicle. the nisin-loaded nanoparticles were prepared using colloidal dispersion of the chitosan/alginate polymers in the presence of nisin. after the preparation of the nisin-loaded nanoparticles, their physicochemical properties such as size, shape, and zeta potential of the formulations were studied using scanning electron microscope and nanosizer in ... | 2010 | 26781321 |
| antimicrobial resistance of staphylococcus species isolated from lebanese dairy-based products. | the study evaluated the antimicrobial resistance of molecularly characterized strains of staphylococcus aureus and s. saprophyticus isolated from 3 lebanese dairy-based food products that are sometimes consumed raw: kishk, shanklish and baladi cheese. suspected staphylococcus isolates were identified initially using standard biochemical tests, then strains that were confirmed by polymerase chain reaction (29 s. aureus and 17 s. saprophyticus) were evaluated for their susceptibility to different ... | 2012 | 24988395 |
| high-throughput assessment of bacterial growth inhibition by optical density measurements. | the increasing incidence of antibiotic-resistant bacterial infections both in hospitals and in the community intensifies the need for new antibacterial strategies and targets. although high-throughput screening against live bacteria allows rapid discovery of compounds with growth-inhibitory activities, these efforts have failed to fill the pipeline with the anticipated antibacterial compounds because target identification is often onerous. recently, a strategy was reported that employs a bacteri ... | 2010 | 23839976 |
| "inducible clindamycin resistance in staphylococcus aureus isolated from clinical samples". | increasing frequency of methicillin resistant staphylococcus aureus (mrsa) infections and changing patterns in antimicrobial resistance have led to renewed interest in the use of macrolide-lincosamide-streptogramin (mls) antibiotics to treat such infections. inducible macrolides, lincosamides, type b streptogramins (mls(bi)) resistance has to be identified to avoid clinical failure of clindamycin therapy. hence we wanted to study the incidence of inducible clindamycin resistance in mrsa and meth ... | 2010 | 22471195 |
| prevalence of community acquired mrsa in a tertiary care facility. | traditionally, methicillin resistant staphylococcus aureus (mrsa) is considered as a nosocomial pathogen, but an increasing prevalence of community acquired mrsa is being reported worldwide including india, which implies a strategic change in the antibiotic of choice for treatment of community acquired staphylococcal infections, which till now is cloxacillin. this study is aimed at identifying the prevalence and susceptibility characteristics of community acquired mrsa in our hospital. the study ... | 2010 | 22471193 |
| update on infections in articular prosthesis. | the implantation of joint prostheses, especially for the hip and knee, is becoming increasingly common. this provides a significant reduction in discomfort and an immeasurable improvement in patient mobility. reviews of the worldwide literature indicate that 1 to 5% of these prostheses become infected, although it is important to remember that as the number of operations performed to implant these prosthesis increases, so will the number of cases of this type of infection. gram-positive bacteria ... | 2017 | 27026957 |
| sacral neuromodulator interstim surgical site infection: two case reports. | : the surgical site infection rate of sacral neuromodulator placement for the treatment of refractory urge urinary incontinence is reported to be between 5% and 7.9%. our objective was to report the investigation process of these infections and a possible source for their occurrence. | 2010 | 22453623 |
| methicillin and vancomycin resistant s. aureus in hospitalized patients. | s. aureus is the major bacterial cause of skin, soft tissue and bone infections, and one of the commonest causes of healthcare-associated bacteremia. hospital-associated methicillin-resistant s. aureus (mrsa) carriage is associated with an increased risk of infection, morbidity and mortality. screening of high-risk patients at the time of hospital admission and decolonization has proved to be an important factor in an effort to reduce nosocomial transmission. the electronic database pub med was ... | 2010 | 20927290 |
| purulent skin and soft tissue infection: antibiotic selection in the community. | community-acquired methicillin-resistant staphylococcus aureus (ca-mrsa) requently causes skin and soft tissue infections (sstis). referring primary care physicians often prescribe inactive antibiotics when referring sstis caused by mrsa for incision and debridement. | 2010 | 23804610 |
| evaluation of therapeutic effects and pharmacokinetics of antibacterial chromogenic agents in a silkworm model of staphylococcus aureus infection. | the therapeutic effect of dye compounds with antibacterial activity was evaluated in a silkworm model of staphylococcus aureus infection. among 13 chromogenic agents that show antibacterial activity against s. aureus (mic = 0.02 to 19 μg/ml), rifampicin had a therapeutic effect. the ed(50) value in the silkworm model was consistent with that in a murine model. other 12 dyes did not increase survival of the infected silkworms. we examined the reason for the lack of therapeutic efficacy. amidol, p ... | 2010 | 22491238 |
| greater risk of death in people with cystic fibrosis and mrsa. | detection of meticilin-resistant staphylococcus aureus (mrsa) in patients with cystic fibrosis is associated with lower survival rates. | 2010 | 28076039 |
| catalase-negative staphylococcus aureus isolated from a diabetic foot ulcer. | we report a catalase-negative staphylococcus aureus isolated from a 56-year-old male diabetic patient with foot ulcer who attended our surgery ward. species identification was confirmed by gram staining, standard biochemical tests and pcr amplification of the nuc and fem genes. antibiotic susceptibility showed that the strain was sensitive to imepenem, chloramphenicol, amoxicillin, vancomycin and resistant to oxacillin, penicillin, ceftriaxone, erythromycin, clindamycin, and amikacin. clinicians ... | 2010 | 22347567 |
| sensitivity pattern of methicillin resistant staphylococcus aureus isolated from patients admitted in a tertiary care hospital of pakistan. | methicillin resistant staphylococcus aureus (mrsa) is a major nosocomial pathogen causing significant morbidity and mortality. the aim of this study was to evaluate in vitro activities of different antibiotics against methicillin resistant staphylococcus aureus. | 2010 | 22347563 |
| detection of enterotoxigenic staphylococcus aureus isolates in domestic dairy products. | staphylococcus aureusis a one of the most frequent causes of food poisoning (fp) in dairy products. the main etiologic agents of fp are staphylococcal enterotoxins (se). there are different types of se; types a (sea) and b (seb) are the most clinically important enterotoxins. traditional dairy products are still produced in small batches and sold by some vendors without a permit from the ministry of health. this study focuses on the molecular and serological detection of enterotoxigenic staphylo ... | 2010 | 22347562 |
| staphylococcus aureus and chronic airway disease. | staphylococcus aureus (s. aureus) is correlated with the development of persistent severe inflammatory disease of the upper airway including chronic rhinosinusitis with nasal polyps. this inflammation of the upper airways is characterized by a t-helper 2-driven disease: interleukin-5 is significantly increased and local production of immunoglobulin e is observed. s. aureus and its enterotoxins are deregulating the tissue inflammation at different levels: structural cells and the innate and adapt ... | 2010 | 23282714 |
| antibacterial activity of extracts of acacia aroma against methicillin-resistant and methicillin-sensitive staphylococcus. | antibacterial activity of organic and aqueous extracts of acacia aroma was evaluated against methicillin-resistant staphylococcus aureus (mrsa), methicillin sensitive staphylococcus aureus (mssa) and methicillin-resistant staphylococcus epidermidis. inhibition of bacterial growth was determined using agar diffusion and bioautographic methods. among all assayed organic extracts only ethanolic and ethyl acetate extracts presented highest activities against all tested staphylococcus strains with mi ... | 2010 | 24031532 |
| effect of galbanic acid, a sesquiterpene coumarin from ferula szowitsiana, as an inhibitor of efflux mechanism in resistant clinical isolates of staphylococcus aureus. | galbanic acid, a sesquiterpene coumarin from ferula szowitsiana roots, was investigated for its potentiating effect on the antimicrobial activity of antibiotics as well as ethidium bromide, in 6 multidrug resistance (mdr) clinical isolates of staphylococcus aureus. galbanic acid had inhibitory effect on none of the isolated bacteria tested (up to 800 μg /ml). the mic range of ciprofloxacin, tetracycline and ethidium bromide, against all tested s. aureus were 10-80, 10-80 and 4-16 μg/ml, respecti ... | 2010 | 24031531 |
| antibacterial susceptibility patterns and cross-resistance of methicillin resistant and sensitive staphyloccus aureus isolated from the hospitalized patients in shiraz, iran. | nosocomial infections caused by methicillin-resistant staphylococci (mrsa) pose a serious problem in many countries. this study aimed to determine the antibacterial susceptibility patterns of methicillin sensitive and resistant staphylococcus aureus isolates from the hospitalized patients. totally 356 isolates of staphylococcus aureus (s. aureus) including 200, 137 and 19 corresponding to mssa, mrsa, and intermediate mrsa strains, respectively were isolated. antibacterial susceptibility patterns ... | 2010 | 24031530 |
| antiviral activity of borage (echium amoenum). | borage (echium amoenum) is a large annual plant of the boraginaceae family that grows in most parts of europe and in northern parts of iran. the flower of borage is used as a medicinal herb in various countries as an antifebrile and antidepressant, for treatment of stress, circulatory heart diseases and pulmonary complaints, as a poultice for inflammatory swellings, as a diuretic, laxative, emollient and demulcent, and recently as a possible cancer protective factor. the iranian borage is used i ... | 2010 | 22371772 |
| evaluation of nisin f in the treatment of subcutaneous skin infections, as monitored by using a bioluminescent strain of staphylococcus aureus. | the potential of nisin f as an antimicrobial agent in treating subcutaneous skin infections was tested in vivo by infecting c57bl/6 mice with a bioluminescent strain of staphylococcus aureus (xen 36). strain xen 36 has the luxabcde operon located on a native plasmid. mice were grouped into four groups: infected with strain xen 36 and treated with nisin f, infected with strain xen 36 and treated with saline (placebo), not infected and treated with nisin (control) and not infected and not treated ... | 2010 | 26781114 |
| the use of a new wound alginogel for the treatment of partial-thickness hand burns. | the following retrospective analysis reports on patients with partial-thickness wounds admitted to the burn unit of the general hospital of athens who were treated with a new alginogel and were later compared to the burn center's standard treatment. | 2010 | 25901464 |
| hydromyelia secondary to spinal epidural abscess. a case report. | spinal epidural abscess (sea) is a rare condition that can be fatal if untreated. risk factors are immunocompromised states as well as spinal procedures including epidural anesthesia and spinal surgery. the signs and symptoms of sea are nonspecific and can range from low back pain to sepsis. the treatment of choice is surgical decompression followed by four to six weeks of antibiotic therapy. the most common causative organism in sea is staphylococcus aureus and spread is usually haematogenous o ... | 2010 | 24148595 |
| open drainage versus percutaneous drainage in the treatment of tropical pyomyositis. prospective and randomized study. | to compare the results from treating tropical pyomyositis through percutaneous drainage of abscesses versus open surgical drainage of abscesses, by means of a randomized prospective study. | 2017 | 27022550 |
| current microbiology of surgical site infections associated with breast cancer surgery . | surgical site infections (ssi) are the most common complications of breast cancer surgery. the authors identified 35 cases of ssi in the m.d. anderson cancer center (houston, tx) over a 7-month study period. monomicrobial infections predominated (69%) with staphylococcus aureus being isolated most often. a wide variety of gram-positive and gram-negative organisms were isolated from the 31% of polymicrobial infections, suggesting the need for broad-spectrum coverage at least until culture res ... | 2010 | 25902178 |
| oxacillin resistant staphylococcus aureus among hiv infected and non-infected kenyan patients. | infections due to methicillin resistant s. aureus (mrsa) present global challenges to clinicians since therapeutic options are limited and suboptimal dosing contributes to heightened mortality and increased length of hospital stay particularly among the hiv infected patients. | 2010 | 23057279 |
| simultaneous bilateral spontaneous pneumothorax: a rare emergency clinical condition. | spontaneous pneumothorax is a disease that may cause serious respiratory distress and can be a life-threatening condition. a total of 1.3% of all spontaneous pneumothorax cases are simultaneous bilateral spontaneous pneumothorax (sbsp). in this study, because of its rarity, we discuss sbsp cases in light of previously reported cases. | 2010 | 25610108 |
| occurrence of staphylococcus aureus in raw milk produced in dairy farms in são paulo state, brazil. | the objective of the present study was to evaluate the occurrence of staphylococcus aureus in milk produced in 37 farms located in the regions of ribeirão preto and são carlos, state of são paulo, brazil. two-hundred and eight samples of milk from individual cows showing subclinical mastitis, and 37 samples of bulk tank milk were analyzed. s. aureus strains were detected in 18 (7.3%) milk samples: 14 (6.7%) from samples of individual cows, and 4 (10.8%) from bulk tank milk. two individual milk s ... | 2010 | 24031507 |
| epidemiology and antimicrobial resistance of staphylococci isolated from different infectious diseases. | a total of 187 isolates from 470 clinical specimens were collected from three hospitals in el-minia governorate and identified as 132 staphylococcus aureus strains and 55 coagulase-negative staphylococci (cons) strains. susceptibility of isolates to antimicrobial agents was tested by the agar dilution method. the isolated s. aureus strains showed low resistance to vancomycin (1.5%), amikacin (2.3%) and gatifloxacin (3.8%). vancomycin was the most effective antibiotic against cons. the ampicillin ... | 2010 | 24031501 |
| evaluation of different methods for detecting methicillin resistance in staphylococcus aureus isolates in a university hospital located in the northeast of brazil. | many methods have been described for the detection of methicillin-resistant staphylococcus aureus (mrsa), but the heterogeneous expression of methicillin resistance affects the reliability of these methods. the aim of the present study was to evaluate some methods for detecting methicillin resistance in staphylococcus aureus isolates in a university hospital located in the northeast of brazil. among the isolates, 15 were methicillin-susceptible and 45 were methicillin-resistant, including low-le ... | 2010 | 24031498 |
| phenotypic detection of constitutive and inducible clindamycin resistance in clinical isolates of staphylococcus aureus and coagulase negative staphylococcus on routine susceptibility plate. | increasing frequency of methicillin resistant staphylococcus aureus infections and changing patterns in antimicrobial resistance have led to renewed interest in the use of macrolidelincosamide-streptogramin antibiotics. however therapy may fail either due to constitutive or inducible resistance. this study was undertaken to detect different phenotypes including inducible clindamycin resistance in clinical isolates of staphylococcus aureus and coagulase negative staphylococcus. four hundred sixty ... | 2010 | 22468547 |
| the effectiveness of chlorhexidine bath in the prevention of methicillin resistant staphylococcus aureus (mrsa) in the adult inpatient wards. a systematic review. | | 2010 | 27820383 |
| a case of community-associated methicillin-resistant staphylococcus aureus infections in a community hospital. | infections caused by methicillin-resistant staphylococcus aureus (mrsa) have recently occurred in communities in people lacking known healthcare risk factors. this mrsa infection is referred to as community-associated mrsa (ca-mrsa) infection, and is distinct from hospital-associated mrsa infection, which occurs in people with risk factors. we experienced a patient diagnosed with ca-mrsa cellulitis, as culture of pus revealed mrsa and he had not been exposed to healthcare environments for the pa ... | 2010 | 25649545 |
| evaluation of tigecycline activity against methicillin-resistante staphylococcus aureus isolated from biological samples. | tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. it has broad spectrum activity, including staphylococcus aureus infections. this is the first study that evaluated the activity of tigecycline against staphylococcus aureus isolated from biological samples in iran. in vitro activity of tigecycline against 160 staphylococcus aureus including 99 methicillin-resistant s. aureus and 61 methicillin-susceptible s. aureus from inpatients at imam khomeini hospi ... | 2010 | 24363708 |
| mode of action and in vitro susceptibility of mastitis pathogens to macedocin st91km and preparation of a teat seal containing the bacteriocin. | mastitis is considered to be the most economically costly disease affecting the dairy industry. regular dosage of animals with antibiotics, including use of prophylactic concentrations, may select for resistant strains. the purpose of this study was to determine the mode of action of a new bacteriocin (macedocin st91km), to evaluate the antimicrobial resistance of mastitis pathogens to antibiotics commonly used in treatment remedies, and to introduce the possible use of an alternative antimicrob ... | 2010 | 24031473 |
| association of hiv with breast abscess and altered microbial susceptibility patterns. | background: breast abscesses account for 15% of surgical day cases seen in the uth. nearly all of these cases occur in lactating women. pre-natal hiv prevalence among women seeking care at uth was estimated at 25% as of 2004. baseline surveys have shown that up to 60% of soft tissue infections presenting to the uth are hiv related. objectives: to determine if hiv infection is a risk factor for the development of breast abscesses in women presenting to the university teaching hospital (uth) in lu ... | 2010 | 23170038 |
| prevalence of genes encoding bi-component leukocidins among clinical isolates of methicillin resistant staphylococcus aureus. | staphylococcus aureus has been recognized as a major human pathogen and is the major cause of nosocomial infections. gamma-toxin, leukocidin and other bi-component toxins are a family of proteins encoded by the hlg and luk-pv, respectively. panton-valentine leukocidin (pvl) is an example of these toxins and causes leukocyte destruction and tissue necrosis. the aim of this study was to determine the prevalence of bi-component leukocidin in methicillin resistant staphylococcus aureus (mrsa) isolat ... | 2010 | 23112984 |
| comparison of different phenotypic and molecular methods for detection of methicillin-resistant staphylococcus aureus in intensive care patients. | detection of methicillin-resistant staphylococcus aureus (mrsa) has been problematic ever since its discovery. this work was performed to evaluate the effectiveness of different phenotypic methods for mrsa detection in intensive care patients. three hundred and eighty-nine specimens from 100 patients were inoculated onto mannitol salt agar. all s. aureus isolates were examined by four selective culture media [orsab, mso, msa-cefox, oas], two disc diffusion methods [cdd and odd], and microscan pa ... | 2010 | 23082486 |
| pre-operative screening for methicillin-resistant staphylococcus aureus (mrsa) infection: a review of the clinical-effectiveness and guidelines. | | 2010 | 22977404 |
| amplitude-integrated electroencephalography and mri findings in a case of severe neonatal methicillin-resistant staphylococcus aureus meningitis. | methicillin-resistant staphylococcus aureus (mrsa) can cause serious infection among hospitalised patients. the emergence of community acquired strains of mrsa (ca-mrsa) increases the potential exposure of newborns. the high incidence of reported meningitis in neonates in large ca-mrsa outbreaks suggests increased virulence in the neonatal population. the authors describe a case of severe meningitis due to mrsa in a previously healthy neonate and include findings from amplitude-integrated electr ... | 2010 | 22802366 |
| a case of mistaken identity: subacute bacterial endocarditis associated with p-antineutrophil cytoplasmic antibody. | seventeen cases of subacute bacterial endocarditis (sbe) associated with antineutrophil cytoplasmic antibody (anca) have been reported. fifteen such cases have been associated with c-anca postivity and two with dual p-anca and c-anca antibodies. the authors describe a 61-year-old man with sole p-anca positive autoantibodies on immunofluorescence presenting with staphylococcus aureus sbe of the aortic valve. to the best of our knowledge this is the only reported case of sole p-anca positive sbe. ... | 2010 | 22802277 |
| spontaneous abscess of the lumbar spine presenting as subacute back pain. | a 52-year-old lady was admitted with back pain, fever and reduced sensation in her left leg. soon after admission she developed acute urinary retention. she underwent urgent mri of the spine which showed an epidural abscess compressing the thecal sac which was treated with neurosurgical decompression and intravenous/oral antibiotics. cultures from theatre grew staphylococcus aureus sensitive to flucloxacillin. after 12 weeks of intravenous/oral antibiotics, she was discharged without any neurolo ... | 2010 | 22778378 |
| synthesis and cloxacillin antimicrobial enhancement of 2-methylsulfonylimidazolyl-1,4-dihydropyridine derivatives. | hospital-acquired methicillin-resistant staphylococcus aureus (mrsa) has been a major problem worldwide in chemotherapy of infection disease. this study was designed to assess the enhancing effects of a new group of dihydropyridine-3,5dicarboxamides, in combination with cloxacillin with distinctly different mechanisms of action against mrsas. | 2010 | 22615605 |
| influence of age on frequency of vancomycin dosing. | vancomycin is commonly prescribed at the authors' institution because of a high prevalence of invasive infections caused by methicillin-resistant staphylococcus aureus (mrsa) in a generally younger population. the most commonly prescribed empiric dosing interval is every 12 h (q12h). however, observations have suggested that younger adult patients require more frequent dosing, such as every 8 h (q8h). initial underdosing of vancomycin may increase the risk of antibiotic failure. | 2010 | 22478948 |
| continuous infusion of nafcillin for sternal osteomyelitis in an infant after cardiac surgery. | we report the use of the continuous infusion of nafcillin for the treatment of an infant who had methicillinsusceptible staphylococcus aureus sternal osteomyelitis not responsive to traditional nafcillin dosing. the patient was successfully treated with surgical debridement and the continuous infusion of nafcillin. to our knowledge, this is the first report describing the successful use of the continuous infusion of nafcillin to treat an infant who had sternal osteomyelitis after cardiac surgery ... | 2010 | 22477793 |
| in silico characterization of thermoactive, alkaline and detergent-stable lipase from a staphylococcus aureus strain. | bacterial true lipases having thermo and alkaline stability are highly attractive for their industrial production of pharmaceuticals, agrochemicals, cosmetics, and flavour. staphylococcus aureus lipase (sal3) remains active at temperatures 40-60°c, with an optimum temperature of 55°c and an optimum ph of 9.5 stable over a range of 5-12. detailed understanding of the structure and insight into the activity of such lipase would aid in engineering lipases that would function in the desired extreme ... | 2010 | 22430359 |
| clinical significance of the isolation of staphylococcus epidermidis from bone biopsy in diabetic foot osteomyelitis. | coagulase-negative staphylococci are considered as microorganisms with little virulence and usually as contaminants. in order to establish the role of staphylococcus epidermidis as a pathogen in diabetic foot osteomyelitis, in addition to the isolation of the sole bacterium from the bone it will be necessary to demonstrate the histopathological changes caused by the infection. | 2010 | 22396808 |
| daptomycin: a novel lipopeptide antibiotic against gram-positive pathogens. | the aim of this review is to summarize the historical background of drug resistance of gram-positive pathogens as well as to describe in detail the novel lipopeptide antibiotic daptomycin. pharmacological and pharmacokinetic aspects are reviewed and the current clinical use of daptomycin is presented. daptomycin seems to be a reliable drug in the treatment of complicated skin and skin structure infections, infective right-sided endocarditis, and bacteremia caused by gram-positive agents. its uni ... | 2010 | 21694898 |
| sepicanin a- a new geranyl flavanone from artocarpus sepicanus with activity against methicillin-resistant staphylococcus aureus (mrsa). | bioassay-guided fractionation of the etoh extract of artocarpus sepicanus diels leaves has led to the isolation of a new geranyl flavanone (1), along with the known compounds, afzelechin-3-o-α-l-rhamnopyranoside and β-sitosterol glucoside. the structure of the new compound was established by uv, ir, hresims, 1d and 2d nmr experiments. antimicrobial testing of the three compounds indicated that 1 displayed a significant selective antibacterial activity against methicillin-resistant staphylococcus ... | 2009 | 27594928 |
| daptomycin for the treatment of osteomyelitis associated with a diabetic foot ulcer. | this report describes a case of staphylococcus aureus osteomyelitis associated with a chronic foot ulcer that was successfully treated with surgical debridement and 6 weeks of daptomycin therapy. daptomycin was chosen because of its excellent activity against the causative organism and the patient's history of penicillin allergy. its tolerability and ease of administration also facilitated long-term outpatient management. the present case provides further evidence that supports consideration ... | 2009 | 25902713 |
| methicillin-resistant staphylococcus aureus infectious scleritis after vitrectomy for endophthalmitis. | to report a case of methicillin-resistant staphylococcus aureus infectious scleritis after vitrectomy for endophthalmitis. | 2009 | 25389862 |
| integrated clinical care pathway for managing necrotising soft tissue infections. | necrotising soft tissue infections (nsti) are relatively common infections with high morbidity and mortality rate, as they often present late in their course. quick and aggressive surgical treatment improves survival and decreases hospital stay. | 2009 | 23133168 |
| efficacy of polyhexamethylene biguanide-containing antimicrobial foam dressing against mrsa relative to standard foam dressing. | many modern foam wound dressings possess a variety of attributes that are designed to create a supportive wound-healing environment. these attributes include absorbing exudate, providing optimum moisture balance at the wound surface, and preventing maceration of surrounding tissue. however, studies suggest that controlling wound bioburden should also be targeted when developing wound therapeutics. thus, traditional foam dressings may absorb a copious amount of fluid, but may also provide a ... | 2009 | 25903814 |
| construction and purification of his-tagged staphylococcal arsb protein, an integral membrane protein that is involved in arsenical salt resistance. | bacterial resistance to arsenical salts encoded on plasmid pi258 occurs by active extrusion of toxic oxyanions from cells of staphylococcus aureus. the operon encodes for three gene products: arsr, arsb and arsc. the gene product of arsb is an integral membrane protein and it is sufficient to provide resistance to arsenite and antimonite. a poly his-arsb fusion protein was generated to purify the staphylococcal arsb protein. cells containing the his-tagged arsb gene were resistant to arsenite an ... | 2009 | 23100771 |
| community-associated methicillin-resistant staphylococcus aureus infections in the athlete. | community-associated methicillin-resistant staphlococcus aureus (ca-mrsa) has become of increasing concern in the athletic setting. appropriate recognition, treatment, and prevention measures are all paramount to protect individual athletes and teamwide outbreaks. | 2009 | 23015900 |
| extra cleaner on wards reduces mrsa infections. | mrsa infections having one extra cleaner on a ward can apparently benefit patients with regard to meticillin-resistant staphylococcus aureus (mrsa). | 2009 | 28075940 |
| staphylococcal endocarditis presenting with a renal infarct in a patient with acute lymphoblastic leukemia. | we present here a patient with acute lymphoblastic leukemia (all) and who developed infective endocarditis during induction chemotherapy with prednisolone, l-asparaginase (leunase), vincristine and adriamycin. the patient did not have a history of a central venous catheter. sharp flank pain and fever occurred on the 25(th) day of induction chemotherapy. in addition, a renal infarct and movable vegetations on the mitral valve were detected on the abdominal computed tomography (ct) and echocardiog ... | 2008 | 19688123 |
| azoreductase in staphylococcus aureus. | azoreductase(s) catalyze a nad(p)h-dependent reaction in bacteria to metabolize azo dyes to colorless aromatic amines. azoreductases from bacteria represent a novel family of enzymes with little similarity to other reductases. this unit will describe the current methods for measuring azoreductase from staphylococcus aureus, which has been suggested to serve as a model strain to study the azo dye degradation by human skin microflora. | 2009 | 23045013 |
| effects of opium smoking cessation on the nasopharyngeal microbial flora. | to determine the effect of opium smoking cessation on the frequency and type of microorganisms in the nasopharynx of opium smokers. | 2009 | 24494075 |
| a thin layer electrochemical cell for disinfection of water contaminated with staphylococcus aureus. | a thin layer electrochemical cell was tested and developed for disinfection treatment of water artificially contaminated with staphylococcus aureus. electrolysis was performed with a low-voltage dc power source applying current densities of 75 ma cm(-2) (3 a) or 25 ma cm(-2) (1 a). a dimensionally stable anode (dsa) of titanium coated with an oxide layer of 70%tio2 plus 30%ruo2 (w/w) and a 3 mm from a stainless-steel 304 cathode was used in the thin layer cell. the experiments were carried out u ... | 2009 | 24031410 |
| phage typing, pcr amplification for meca gene, and antibiotic resistance patterns as epidemiologic markers in nosocomial outbreaks of methicillin resistant staphylococcus aureus. | staphylococcus aureus is one of the major causes of community and hospital-acquired infections. bacteriophage considered as a major risk factor acquires s. aureus new virulence genetic elements. a total number of 119 s. aureus isolated from different specimens obtained from (rkh) were distinguished by susceptibility to 19 antimicrobial agents, phage typing, and pcr amplification for meca gene. all of mrsa isolates harbored meca gene, except three unique isolates. the predominant phage group is b ... | 2009 | 23961041 |
| combined application of origanum vulgare l. essential oil and acetic acid for controlling the growth of staphylococcus aureus in foods. | this study evaluated the occurrence of an enhancing inhibitory effect of the combined application of origanum vulgare l. essential oil and acetic acid against staphylococcus aureus by the determination of fractional inhibitory concentration (fic) index and kill-time assay in nutrient broth, meat broth and in a food model (meat pieces). acetic acid showed mic and mfc of 0.6 and 1.25 μl.ml(-1), respectively. for o. vulgare essential oil mic and mbc were 1.25 and 2.5 μl.ml(-1), respectively. fic in ... | 2009 | 24031377 |
| detection of methicillin resistance and slime factor production of staphylococcus aureus in bovine mastitis. | this study aimed to detect methicillin resistant and slime producing staphylococcus aureus in cases of bovine mastitis. a triplex pcr was optimized targetting 16s rrna, nuc and meca genes for detection of staphylococcus species, s. aureus and methicillin resistance, respectively. furthermore, for detection of slime producing strains, a pcr assay targetting icaa and icad genes was performed. in this study, 59 strains were detected as s. aureus by both conventional tests and pcr, and 13 of them we ... | 2009 | 24031354 |
| treating methicillin-resistant staphylococcus aureus infections with compounded vancomycin preparations. | methicillin-resistant staphylococcus aureus infections have been an ongoing problem with institutions. unfortunately, the problem has crossed over into the community setting. drug resistance develops so rapidly that it is difficult for drug manufacturers to develop new treatment options in a timely manner. compounding pharmacists can help physicians treat their methicillin-resistant staphylococcus aureus patients by assisting them in developing new dosage forms or therapies to treat these diffic ... | 2016 | 23970004 |
| methicillin-resistant staphylococcus aureus: a growing risk in the hospital and in the community. | methicillin-resistant staphylococcus aureus is a common and continuously growing cause of nosocomial and community-acquired infections. the type, disease severity, and clinical outcomes of these infections, as well as the genotypic and susceptibility patterns of the bacteria differ according to the setting in which the infection occurs-a healthcare facility or the community setting. the incidence of these infections in the community setting has been growing consistently in the past decade or so. ... | 2009 | 25126276 |
| ocurrence of staphylococcus aureus and multiplex pcr detection of classic enterotoxin genes in cheese and meat products. | multiplex pcr was used to investigate the presence of enterotoxins genes (sea, seb, sec, sed and see) and fema gene (specific for staphylococcus aureus) in coagulase-positive staphylococci (cps) isolated from cheese and meat products. from 102 cps isolates, 91 were positive for fema, 10 for sea, 12 for sed and four for see. | 2009 | 24031334 |
| detection of oxacillin resistance in staphylococcus aureus isolated from the neonatal and pediatric units of a brazilian teaching hospital. | to determine, by phenotypic and genotypic methods, oxacillin susceptibility in staphylococcus aureus strains isolated from pediatric and neonatal intensive care unit patients seen at the university hospital of the botucatu school of medicine. | 2009 | 23818792 |
| multivalent anchoring and oriented display of single-domain antibodies on cellulose. | antibody engineering has allowed for the rapid generation of binding agents against virtually any antigen of interest, predominantly for therapeutic applications. considerably less attention has been given to the development of diagnostic reagents and biosensors using engineered antibodies. recently, we produced a novel pentavalent bispecific antibody (i.e., decabody) by pentamerizing two single-domain antibodies (sdabs) through the verotoxin b subunit (vtb) and found both fusion partners to be ... | 2009 | 22346702 |
| quantitation of bacteria in clean, nonhealing, chronic wounds. | quantitative swabs were obtained from 30 clean, chronic wounds on 30 different patients during one visit. the number of organisms and the predominant organism were determined. all samples were processed under both aerobic and anaerobic conditions. nineteen (63%) of the 30 clean wounds had bacterial levels that were ≥ 105 cfu/cm2. there was no correlation between ≥ 105 cfu/cm2 and delayed wound healing. the most frequently isolated predominant organism was staphylococcus aureus. in these cl ... | 2008 | 25941776 |
| community-associated methicillin-resistant staphylococcus aureus in the pediatric population. | to review the epidemiology and prevalence of community-associated methicillin-resistant staphylococcus aureus (ca-mrsa), define the differences between community-acquired and hospital-acquired strains, highlight the advantages and disadvantages of antibiotics commonly used to treat infections caused by this pathogen, and identify strategies to limit the spread of this organism and prevent future outbreaks. | 2008 | 23055880 |
| a novel terpenoid from elephantopus scaber - antibacterial activity on staphylococcus aureus: a substantiate computational approach. | staphylococcus aureus has gained much attention in the last decade as it is a major cause of the urinary tract infection in diabetic patients. the extended spectrum β-lactamases (esβl) producers are highly resistant to several conventional antibiotics. this limits the therapeutic options.hence efforts are now taken to screen few medicinal plants, which are both economic and less toxic. among the several plants screened, we have chosen the acetone extract of elephantopus scaber from which we puri ... | 2008 | 23675090 |
| clinical pharmacology of linezolid: an oxazolidinone antimicrobial agent. | the oxazolidinones are a new class of antibiotics whose mechanism of action is the inhibition of bacterial protein synthesis by binding to the 50s ribosomal subunit. linezolid is the first member of this class of antibiotics to be approved by the us fda and other regulatory bodies for the treatment of infections caused by antibiotic-resistant gram-positive pathogens, such as methicillin-resistant staphylococcus aureus, glycopeptide-intermediate s. aureus and vancomycin-resistant enterococcus, in ... | 2008 | 24410550 |
| antibacterial activity of four mouthrinses containing triclosan against salivary staphylococcus aureus. | the maximum inhibitory dilution (mid) of triclosan-based mouthwashes against 28 staphylococcus aureus strains was evaluated. dilutions ranging from 1/10 to 1/655,360 were prepared. strains were inoculated using a steers multipoint inoculator. the mid was considered as the maximum dilution capable of inhibiting microorganism growth. the mouthwashes presented different mids. | 2008 | 24031267 |
| submerged culture conditions for the production of mycelial biomass and antimicrobial metabolites by polyporus tricholoma mont. | basidiomycete fungi of the polyporus genus are a source of secondary metabolites which are of medicinal interest as antibacterial compounds. as these substances are produced in a small amount by the fungi, the study of the cultivation conditions in vitro that could possibly optimize their production seems of major importance. the effects of glucose and lactose, ph and agitation on biomass concentration and on the specific growth rate caused by the basidiomycete polyporus tricholoma were investig ... | 2008 | 24031266 |
| comparing the disinfecting efficacies of micro 10, deconex, alprocid and microzid af on the microorganisms on radiographic equipments. | the exposure and processing of dental radiographs are not routinely associated with the spatter of blood or saliva; however, infection control is still an issue resulting from contaminated equipment, supplies, film packets or cassettes. this study aimed at comparing the efficacy of four commercially available disinfectants on microorganisms present on the equipment of radiology department. | 2008 | 23289058 |
| [blood vessel reconstruction infections: a practical view]. | infection represents a serious complication in vascular surgery. the average of 2-3% of reconstructions are involved. the article offers a review of current diagnosis and treatment of infection after vascular reconstruction. emphasis is put on early diagnosis and its impact on prognosis of patients. we summarize the practical potential of surgical treatment. the situation is illustrated by our results from the years 2004-2006. during the last 3 years 19 patients were operated on for infection of ... | 2008 | 23687709 |
| the role of patient isolation and compliance with isolation practices in the control of nosocomial mrsa in acute care. | nosocomial infection remains the most common complication of hospitalisation. despite infection control efforts, nosocomial methicillin resistant staphylococcus aureus (mrsa) transmission continues to rise. various isolation practices are used to minimise mrsa transmission in acute care. however, the effectiveness of these practices has seldom been evaluated. | 2008 | 27819970 |
| the infection control management of mrsa in acute care. | many acute care facilities report endemic methicillin-resistant staphylococcus aureus (mrsa), while others describe the occurrence of sporadic disease outbreaks. the timely implementation of effective infection control measures is essential to minimise the incidence of mrsa cases and the magnitude of disease outbreaks. management strategies for the containment and control of mrsa currently vary between facilities and demonstrate varying levels of effectiveness. | 2008 | 27819923 |
| role of mrsa reservoirs in the acute care setting. | nosocomial infection remains the most common complication of hospitalisation. despite infection control efforts, nosocomial methicillin-resistant staphylococcus aureus (mrsa) transmission continues to rise. the associated costs of increased hospital stay and patient mortality cause considerable burden to the health system. | 2008 | 27819853 |
| postoperative seroma deep to mesh after laparoscopic ventral hernia repair: computed tomography appearance and implications for treatment. | we report the development of a seroma deep to a mesh prosthesis used for laparoscopic ventral hernia repair (lvhr). seroma formation anterior to mesh after lvhr is very common; however, the formation of a deep seroma has been rarely reported in the literature and the imaging appearance of a seroma posterior to mesh after lvhr has not been previously described. we present the imaging appearance and our clinical results of aspirating two seromas posterior to mesh after lvhr. | 2008 | 27303507 |
| hybrid treatment of multiple aortic aneurysms by combined conventional surgery and endovascular aortic repair. | we evaluated the operative results of our treatment for multiple aortic aneurysms by means of a hybrid procedure consisting of a combination of conventional surgical maneuvers and simultaneous or sequential endovascular aortic repair (evar). | 2008 | 23555337 |
| use of daptomycin for treatment of staphylococcus aureus infections. | gram-positive bacteria such as staphylococcus aureus are important human pathogens. an increasing proportion of s. aureus are methicillin resistant. for decades, methicillin-resistant s. aureus infections have been treated with vancomycin, but susceptibility is decreasing, and tissue penetration and safety profile (especially nephrotoxicity) is not ideal. consequently, there is a great need for the development of antibiotics with demonstrated efficacy and safety for infections caused by s. aureu ... | 2007 | 23484602 |
| recent considerations in recurrent cellulitis. | cellulitis is a frequently diagnosed syndrome that causes considerable morbidity. for a subset of patients, recurrent bouts of infection impact their quality of life. most cases are due to b-hemolytic streptococci or staphylococcus aureus. inclusion of interdigital space (toe web) or mucosal (anal) swab cultures may increase the ability to define pathogens among patients with lower extremity cellulitis. the pathogenesis of cellulitis is complex, and more work is needed so that novel therapies an ... | 2007 | 24395486 |
| insights on virulence and antibiotic resistance: a review of the accessory genome of staphylococcus aureus. | staphylococcus aureus continues to be a serious health problem worldwide due to its intrinsic nature of virulence, ability to cause a wide array of infection, and its capacity to develop resistance to a number of antibiotics. the s aureus genome has continually evolved through both mutation and acquisition of exogenous genes, leading to the emergence of antibiotic-resistant strains with the ability for clonal dissemination across nations and continents. methicillin-resistant s aureus (mrsa) is ... | 2007 | 25942745 |
| peritonsillar abscess - do we need anaerobic cover? | to find out the usability and advantage with regard to the advent of new and more costly antibiotics. in the treatment of peritonsillar abscess the demonstration of, both aerobic and anaerobic organisms has raised the question of possible need to treat with antibiotics effective against anaerobes. it was in this very context that this study was planned to find out if we still have an economically and easily available antibiotic to treat peritonsillar abscess. | 2007 | 23120440 |
| emrsa-15 bacteremia is not associated with a worse outcome compared with bacteremia caused by multidrug-resistant mrsa. | emrsa-15 (st22-mrsa-iv) is rapidly replacing the endemic st239 health care-associated methicillin-resistant staphylococcus aureus clone in singapore. a one-year single-centre cohort study of inpatients with mrsa bacteremia was performed to determine if bacteremia caused by emrsa-15 was associated with worse outcomes compared to bacteremia caused by the endemic st239 strain. strains were identified by antibiotypes, and subsequent validation was performed on a selected sample of mrsa strains via p ... | 2007 | 23675030 |
| the investigation of bacteriology of chronic suppurative otitis media in patients attending a tertiary care hospital with special emphasis on seasonal variation. | chronic suppurative otitis media takes a lot of time in the hospital outdoors and a considerable amount of o.t. timings. chronic suppurative otitis media may be either active chronic otitis media or a sequel of previous otitis media. | 2007 | 23120410 |
| lens concentration of ofloxacin and lomefloxacin in an experimental endophthalmitis model. | abstract. | 2007 | 24683209 |
| utilizing pharmacy records to assess antibiotic prescribing patterns on the incidence of community-acquired methicillin-resistant staphylococcus aureus infections in children. | to assess the effect of prior antibiotic therapy on the incidence of community-acquired methicillin-resistant staphylococcus aureus (ca-mrsa) infections in children. | 2007 | 23055846 |
| using gamma irradiation and low temperature on microbial decontamination of red meat in iran. | gamma irradiation can be used as one of the most efficient methods to reduce microorganisms in food. the irradiation of food is used for a number of purposes, including microbiological control, insects control and inhibition of sprouting and delay of senescence of living food. the aim of this study was to study effects of gamma irradiation, refrigeration and frozen storage as the combination process for improvement of red meat shelf-life. the bovine meat samples were treated with 0, 0.5, 1, 2 an ... | 2007 | 23100643 |
| consumption of antibiotics in a small pacific island nation: samoa. | high levels of antibiotic use contribute to development of antibiotic resistance. there is little known about levels of antibiotic use in samoa, although anecdotally, there are high levels of use, and a strain of methicillin-resistant staphylococcus aureus may have developed there. the study aimed to gather basic data on levels of antibiotic use in samoa. all those who import medicines into samoa were interviewed; invoices, prescription records in hospitals, pharmacies and health centres were re ... | 2007 | 25214916 |
| linezolid compared with vancomycin for the prevention of methicillin-resistant staphylococcus aureus or staphylococcus epidermidis vascular graft infection in rats: a randomized, controlled, experimental study. | graft infections are severe complications of vascular surgery that may result in amputation or mortality. staphylococci are the most frequent cause of vascular graft infections. | 2007 | 24678116 |