| follow-up after coronary revascularisation in patients with renal transplants. | seven patients underwent coronary revascularisation 12-145 months (mean: 63.4 months) after receiving cadaver renal transplants. there was no operative mortality and in all patients satisfactory renal function was maintained perioperatively. hospital stay ranged from 7 days to 10 days (mean: 8 days). during the period of follow-up (5-72 months, mean: 35 months): one patient remained angina-free at 7 months postoperatively; one patient developed meningitis with listeria monocytogenes 9 weeks afte ... | 1989 | 2624791 |
| [septicemia caused by listeria monocytogenes in the course of aids. predisposing role of associated cirrhosis?]. | | 1989 | 2629576 |
| listeriosis in austria--report of an outbreak in 1986. | in 1986 listeria monocytogenes was isolated from various specimens of 28 patients in austria: 24 were newborn infants, 4 patients were adults (25-73 years). all four adult patients and five of 20 mothers had consumed unpasteurized milk. nine of 20 mothers and two of four adult patients had received vegetables from biologic agriculture. the consumption of raw milk and biologically grown vegetables as possible source of infection cannot be dismissed. the fatality rate (5 of 28) was remarkably low; ... | 1989 | 2631503 |
| the treatment of listeria monocytogenes infections in the central nervous system. | fifty-four cases of listeria monocytogenes meningitis and meningoencephalitis occurred in denmark between 1981 and 1986. the aim of the present study was to consider the antibiotic treatment of these patients, 33 males and 21 females aged from 16 months to 91 years: average (av) 54 years. one or more predisposing factors (pf) were found in 30 patients (55%): steroid treatment (15), cancer (12), alcoholism and/or cirrhosis (10), diabetes mellitus (5), and renal allograft (2). follow-up varied fro ... | 1989 | 2631504 |
| the treatment of listeria monocytogenes septicaemia. | thirty cases of listeria monocytogenes septicaemia occurred in denmark between 1981 and 1986. the aim of this study was to consider the treatment of these patients, 18 males and 12 females aged from 20 to 87 years: average (av) 65 years. one or more predisposing factors (pf) were found in 90% of the patients, mainly cancer (16), steroid treatment (12), cirrhosis and/or alcoholism (8), and diabetes mellitus (3). follow-up varied from 3 months to 5 years. ampicillin (amp) alone or with an aminogly ... | 1989 | 2631505 |
| gene probes for the detection of listeria spp. | four cloned genes of listeria monocytogenes coding for listeriolysin o, beta-haemolysin, camp-factor and a dth-inducing protein (dth-18) were used as gene probes in dna-dna hybridization with different listerial references strains. the fragment encoding for dth-18 is the only probe reacting specifically with pathogenic strains of l. monocytogenes and listeria ivanovii. | 1989 | 2631507 |
| the use of the listeria monocytogenes dth gene for the detection of pathogenic biovars in food. | a gene probe encoding a listeria monocytogenes delayed type hypersensitivity factor (dth) was used for the detection of pathogenic biovars/serovars of the genus listeria isolated from soft cheese. a total of 187 strains, isolated by plating techniques, were screened. the probe reacted with all isolated serovars of l. monocytogenes (except one 4b strain) and did not react with any of the listeria innocua strains. using the mouse bio-assay, as described by kaufmann, a significant correlation was f ... | 1989 | 2631508 |
| serovars of listeria monocytogenes and listeria innocua from food. | the increase of listeriosis outbreaks in recent years has mainly been due to the consumption of contaminated dairy products. this prompted a revision of prevention and control measures. cheese and other foods (meat, poultry meat) were investigated. for isolation, samples were prepared and investigated according to the recommendations of the fda with some modifications including, in particular, sub-enrichment. suspicious colonies were tested biochemically followed by serological identification wi ... | 1989 | 2631511 |
| experimental listeriosis in immunized sheep. | sheep immunized with live or inactivated vaccine were challenged with a virulent strain of listeria monocytogenes. clinical manifestations, penetration of listeriae into the mucous membranes and persistence in organs were noted. bacteriaemia caused by intravenous injection of high doses of virulent strain disappears in 3 days. readily after inoculation, listeriae penetrate into the gastrointestinal tract where they persist for 8 days. listeriae appear from the 3rd day in the conjunctiva and nasa ... | 1989 | 2631514 |
| cellular fatty acids and fatty aldehydes of listeria and erysipelothrix. | the cellular fatty acid composition determined by gas chromatography-mass spectrometry, was found not to differ among listeria monocytogenes, l. innocua and l. ivanovii. slight quantitative differences found in the fatty acid pattern of l. welshimeri were significantly pronounced in l. denitrificans. l. murrayi and l. grayi displayed characteristic closely related patterns. considerable amounts of fatty aldehydes and their dimethyl acetals were observed in hydrolysates and methanolysates of l. s ... | 1989 | 2631734 |
| [neonatal systemic infection caused by listeria monocytogenes]. | listeria monocytogenes is a gram positive cocco-bacillus which causes perinatal infections and also attacks immunocompromised hosts. little is known about it in our medium. as part of a prospective study on neonatal systemic infections, its participation at the national institute of perinatology was researched. during a period of 18 months, 9,283 live newborns were observed, 141 of them were diagnosed with neonatal septicemia. during this period seven neonates had systemic infections due to list ... | 1989 | 2631740 |
| administration of purified anti-l3t4 monoclonal antibody impairs the resistance of mice to listeria monocytogenes infection. | anti-l3t4 monoclonal antibody (gk1.5) treatment significantly impaired the antilisteria resistance of mice as manifested by increased recovery of listeriae from the spleens and livers of anti-l3t4-treated mice and by greater severity of damage to the liver and other organs. anti-l3t4-treated mice demonstrated a profound decrease in their t cell-mediated responses to listeria monocytogenes and its products; they failed to develop delayed type hypersensitivity to soluble listeria antigens in vivo, ... | 1989 | 2642464 |
| antibody-independent protection against pseudomonas aeruginosa infection in mice after treatment with a homologous strain vaccine. | formalin-killed cells of pseudomonas aeruginosa strain m-24 elicited an antibody-independent protective effect against p. aeruginosa infection in mice. the effect was observed as early as 6 h after administration and 100% protection was obtained by 48 h. the protective effect could not be attributed to the production of specific antibody. in m-24-treated mice, the bacteria in the peritoneal cavity, blood and liver were eliminated 12 h after p. aeruginosa infection. this suggested that the protec ... | 1989 | 2644430 |
| listeria monocytogenes septic arthritis. a case report and review of the literature. | septic arthritis is a relatively uncommon manifestation of listeriosis. only four documented cases of listeria arthritis have been reported in the medical literature. we now present a fifth case associated with listeria peritonitis and briefly review the clinical spectrum of articular listeriosis. these cases suggest that (1) the early diagnoses of listeria peritonitis and arthritis require a high degree of clinical suspicion, and (2) a cephalosporin should not be used as the sole antibiotic in ... | 1989 | 2655546 |
| specific gene probe for detection of biotyped and serotyped listeria strains. | a total of 284 strains of listeria, including all known serovars and biovars together with listeria grayi and listeria murrayi, were biotyped and serotyped. biotyping and serotyping could be done in 2 days. a gene probe encoding a delayed hypersensitivity factor (dth) was used in the detection of pathogenic biotypes and serotypes of the tested strains. the gene was found in all 117 tested listeria monocytogenes strains of serogroups 1/2a, 1/2b, 1/2c, 3a, 3b, 3c, 4c, 4d, 4e, 4ab, and 7. it was al ... | 1989 | 2658807 |
| concentrations of ceftazidime, tobramycin and ampicillin in the cerebrospinal fluid of newborn infants. | thirty-five neonates with suspected septicaemia were randomized to treatment with tobramycin or ceftazidime, both in combination with ampicillin. concentrations of antibiotics in the csf were measured 1 h after the third, fourth or fifth injection. in 13 of 17 neonates tobramycin csf concentrations were below 0.5 mg/l. ceftazidime csf concentrations ranged from 2.5 to 17 mg/l, which should be sufficient for treatment of infections with group b streptococci and most aerobic gram-negative bacilli ... | 1989 | 2663518 |
| reduced proliferative response of mouse spleen cells to mitogens during infection with salmonella typhimurium or listeria monocytogenes. | a significant reduction in the mitogenic responsiveness (uptake of 3h-thymidine) of murine spleen cells to concanavalin a, phytohemagglutinin or lipopolysaccharide was observed during infection with virulent salmonella typhimurium. the decreased response to mitogens could be observed independent of the immunity to typhimurium (ity) genotype, i.e. in cba/j mice and c3h/hej mice (ityr) as well as in c57bl/6 mice (itys). because reduced responsiveness was demonstrated in c3h/hej mice, which are sus ... | 1989 | 2666812 |
| efficient natural defense mechanisms against listeria monocytogenes in t and b cell-deficient allogeneic bone marrow radiation chimeras. preactivated macrophages are the main effector cells in an early phase after bone marrow transfer. | radiation chimeras in the early phase after bone marrow transplantation are a good model to study the efficiency of the body's nonspecific defense system represented by macrophages (m phi), polymorphonuclear cells (pmn), and nk cells. these cell types are present in large numbers in spleen and liver at that time, whereas the specific immune system represented by t and b cells is functionally deficient. we previously reported enhanced activities in vitro of m phi (and pmn) from recipient animals ... | 1989 | 2668412 |
| secretion of colony-stimulating factors by t cell clones. role in adoptive protection against listeria monocytogenes. | csf have been postulated to be important mediators of host defenses. the current studies were undertaken to investigate the production of csf by listeria-specific, t cell clones and to assess the participation of csf in anti-listerial host resistance. listeria-specific l3t4+, lyt-2- t cell clones were isolated and expanded by standard techniques. the clones themselves protected mice from listerial challenge when injected intravenously, and supernatants generated from ag-stimulated clones were pr ... | 1989 | 2674280 |
| immunotoxicity of the semiconductor gallium arsenide in female b6c3f1 mice. | the effects of gallium arsenide (gaas) exposure on immunocompetence of b6c3f1 female mice were investigated. gaas was administered as a single intratracheal instillation at doses of 50, 100, and 200 mg/kg. fourteen days after exposure, various cellular and humoral immune parameters were assessed. gaas exposure increased spleen cellularity in a dose-dependent manner. however, the percentages of thy 1.2 positive and ig positive cells were decreased and that of f4/80 positive cells was increased do ... | 1989 | 2695379 |
| latent listeriosis--its diagnosis by bacteriology and serology in five cases. | the failure of agglutination tests in the diagnosis of latent listeriosis (chronic and asymptomatic) are partly due to the fact that deficient antigens in general use have discredited the serology in this infection. however, using good live antigens or antigens devitalized at moderate temperature and conserved by lyophilization, excellent diagnostic results may be obtained by indirect immunofluorescence (iif). we could confirm this again in five women with a history of pregnancy disorders. all h ... | 1989 | 2698579 |
| [listeria endophthalmitis: an uncommon etiology]. | listeria monocytogenes is an uncommon cause infections: to our knowledge this is the seventh case of human endophthalmitis isoleted. an early diagnosis and therapy allowed an excellent functional recovery when compared to the reported cases of the literature. | 1989 | 2698776 |
| options for the treatment of serious infections with interleukin-1. | in this paper, the effects of recombinant human interleukin-1 (il-1) on non-specific resistance to infection are reviewed. in experiments in neutropenic mice, a single injection of a low dose of il-1 (8-800 ng) appears to protect against death from lethal pseudomonas aeruginosa and candida albicans infections. in non-neutropenic mice protection can also be obtained with such dosages of il-1 in infection caused by klebsiella pneumoniae or listeria monocytogenes. low dosages of il-1 are also able ... | 1989 | 2701646 |
| listeria monocytogenes osteomyelitis. | listeria monocytogenes is usually an opportunistic pathogen causing either meningitis or bacteremia in adults. focal infection outside the central nervous system occurs infrequently. we describe two cases of osteomyelitis caused by l monocytogenes. certain characteristics of l monocytogenes may make cure difficult, particularly in a deep-seated focus such as bone, and may warrant special consideration when planning therapy. | 1989 | 2705843 |
| [involvement of the basal ganglia and brain stem in infection by listeria monocytogenes. anatomo-clinical study]. | a case of a patient with haematogeneous infection by listeria monocytogenes, involving the basal and brainstem is reported. clinically the disease manifested by fever and brainstem syndrome of acute onset. the microscopic examination revealed foci of suppurative encephalitis in the brainstem and basal ganglia. the possible pathogenic mechanisms are discussed. it is emphasized that the association of a febrile syndrome with brainstem dysfunction should raise the possibility of infection of the ne ... | 1989 | 2712871 |
| effects of pyran copolymer on host resistance of mice to plasmodium yoelii. | female b6c3f1 mice treated with 25 mg/kg pyran intravenously (i.v.) on days -4 and -3 were more susceptible to nonlethal plasmodium yoelii 17xnl or lethal plasmodium berghei atcc-30090 than untreated mice or mice treated intraperitoneally (i.p.). female b6c3f1 mice treated with pyran i.p. displayed enhanced resistance to listeria monocytogenes as compared to untreated mice or mice given pyran i.v. peritoneal exudate cells (pec) primed by pyran i.p. possessed enhanced ability to kill listeria but ... | 1989 | 2723926 |
| listeriosis in the setting of malignant disease. changing issues in an unusual infection. | thirteen cases of listeria monocytogenes infection occurred at the johns hopkins oncology center over a 10-year period, representing 0.09% of all admissions. these cases principally occurred in patients with underlying hematologic of lymphoreticular malignancy, but in all patients other causes of immune suppression were also present. corticosteroids were the most frequent exogenous cause of immune suppression. bacteremia was detected more frequently than meningitis and in contrast to earlier rep ... | 1989 | 2736496 |
| perinatal listeriosis in dresden 1981-1986: clinical and microbiological findings in 18 cases. | between 1981 and 1986 listeria monocytogenes was isolated from blood cultures, csf, meconium/stools or external swabs from 18 newborn infants of two neonatal intensive care units (icu) in adjacent pediatric clinics of dresden. the epidemiological and clinical data of infants and their mothers, as well as microbiological and laboratory, x-ray, eeg and ultrasonic findings, are presented. all infants had an early onset of their disease. cases were classified as granulomatosis infantiseptica (three ... | 1989 | 2737754 |
| adenosine regulates the respiratory burst of cytokine-triggered human neutrophils adherent to biologic surfaces. | the effect of adenosine on the respiratory burst was investigated using human neutrophils adherent to serum-coated surfaces. adenosine caused complete suppression of the respiratory burst elicited by tnf-alpha, fmlp, or csf for granulocytes; partial suppression of the response to csf for granulocytes/macrophages, staphylococcus aureus, escherichia coli, listeria monocytogenes, or uncoated polystyrene surfaces; and no suppression of the response to pma. in most experiments, 4.7 x 10(-7) m and 2.5 ... | 1989 | 2738405 |
| surveillance of listeriosis in los angeles county, 1985-1986. a first year's report. | after a large food-borne outbreak of listeriosis in los angeles county, california, in 1985, the california state department of health services instituted mandatory reporting of listeria monocytogenes by clinical laboratories. from september 1, 1985, through august 31, 1986, 94 cases of listeriosis were reported in los angeles county for an annual crude incidence rate of 12 cases per million persons. of the 94 cases, 37 (39%) were in neonates and/or their mothers and 57 (61%) were nonperinatal. ... | 1989 | 2742430 |
| tumour necrosis factor in neonatal listeriosis: a case report. | a newborn with fatal neonatal listeriosis developed septic shock, neutropenia, thrombocytopenia and profound hypoxaemia due to severe pulmonary hypertension. tumour necrosis factor alpha, interleukin-1-beta and interferon-gamma serum concentrations were markedly elevated, suggesting the participation of these cytokines in the aetiopathogenesis of shock induced by listeria monocytogenes in the neonate. | 1989 | 2744036 |
| detection of listeriolysin, the thiol-dependent hemolysin in listeria monocytogenes, listeria ivanovii, and listeria seeligeri. | the listeriolysin gene from a weakly hemolytic but virulent strain of listeria monocytogenes serotype 1/2a was cloned in escherichia coli k-12. recombinants were identified on the basis of their cross-reactivities to hyperimmune antisera raised against streptolysin o and listeriolysin. low levels of hemolytic activity were detected in crude lysates of strains harboring the listeriolysin gene. in dna hybridization studies with five dna probes that encoded the listeriolysin gene and surrounding se ... | 1989 | 2744850 |
| [listeria monocytogenes septicemia in acquired immunodeficiency syndrome]. | | 1989 | 2755265 |
| listeria monocytogenes septicemia associated with consumption of salted mushrooms. | listeria monocytogenes septicemia in an 80-year-old man is described. on the day before clinical symptoms appeared the patient had eaten homemade salted mushrooms, rufous milkcap (lactarius rufus fr.). l. monocytogenes serotype 4b was isolated in blood cultures. the mushrooms which had been stored in cold for 5 months before consumption contained the same listeria serotype at a level of 10(6) cfu/g. salt content (nacl) of the mushrooms was 7.5%. fever and diarrhea disappeared with penicillin the ... | 1989 | 2756345 |
| induction of non-specific immunosuppression in mice by mycobacterial infections and its relationship to macrophage activation. | the development of non-specific immunosuppression during the infection of different strains of mice with three mycobacterial species was evaluated by studying the immune response to a heterologous antigen (sheep red blood cells) and comparing it with the induction of non-specific resistance to a listeria monocytogenes challenge. it was shown that early (at 15 days) immunosuppression developed in mycobacterium avium-susceptible mouse strains infected with a high inoculum dose [2.5 x 10(8) colony ... | 1989 | 2762766 |
| listeriosis as an obstetric complication in an immunocompromised patient. | we have reported a case of maternal death associated with listeria monocytogenes septicemia in a woman who was being treated with immunosuppressive drugs for lupus nephritis. this report, coupled with a previous case of l monocytogenes sepsis in a pregnant patient with aids, emphasizes that l monocytogenes infection may be an important, unrecognized pathogen in pregnant women with impaired immunity. | 1989 | 2762887 |
| effects of nisin on growth of bacteria attached to meat. | nisin had an inhibitory effect on gram-positive bacteria (listeria monocytogenes, staphylococcus aureus, and streptococcus lactis) but did not have an inhibitory effect on gram-negative bacteria (serratia marcescens, salmonella typhimurium, and pseudomonas aeruginosa) attached to meat. nisin delayed bacterial growth on meats which were artificially inoculated with l. monocytogenes or staphylococcus aureus for at least 1 day at room temperature. if the incubation temperature was 5 degrees c, grow ... | 1989 | 2764559 |
| listeria monocytogenes meningitis in previously healthy adults. | a retrospective study of four sporadic cases of listeria monocytogenes meningitis is reported. contrary to the conventional epidemiology these patients were adults who were not immuno-compromised. although all four cases produced positive cerebrospinal fluid cultures, in three, listeria was not microscopically identified. protein and glucose contents of cerebrospinal fluids were variable and all samples showed lymphocytic pleocytosis. all four had neutrophil leucocytosis in peripheral blood. the ... | 1989 | 2780465 |
| antibacterial activity of lactobacillus sake isolated from meat. | a total of 221 strains of lactobacillus isolated from meat and meat products were screened for antagonistic activities under conditions that eliminated the effects of organic acids and hydrogen peroxide. nineteen strains of lactobacillus sake, three strains of lactobacillus plantarum, and one strain of lactobacillus curvatus were shown to inhibit the growth of some other lactobacilli in an agar spot test; and cell-free supernatants from 6 of the 19 strains of l. sake exhibited inhibitory activit ... | 1989 | 2782870 |
| impact of genetically regulated t cell proliferation on acquired resistance to listeria monocytogenes. | two lines of mice genetically selected for high and low in vitro responses to pha were used to evaluate the impact of t cell polyclonal expansion on acquired resistance to listeria monocytogenes. the selective breeding induced two major consequences in low responder mice: (1) a reduction of the number of l3t4+ cells and (2) a restriction of t cell expansion upon pha stimulation, predominantly affecting the lyt-2+ subset, and associated with an abridgment of il-2 production. in vivo pha stimulati ... | 1989 | 2783604 |
| first-trimester maternal listeria monocytogenes sepsis and chorioamnionitis with normal neonatal outcome. | a secundigravida developed culture-proved listeria monocytogenes sepsis with signs and symptoms of chorioamnionitis at 13 weeks' gestation. pregnancy termination was refused, and she was treated with intravenous ampicillin and gentamicin followed by oral trimethoprim/sulfamethoxazol. fifteen days after initiation of therapy, an amniotic fluid culture was negative, although uterine tenderness persisted for 7 weeks. a healthy, culture-negative infant was delivered at term. | 1989 | 2783771 |
| comparison of the effects of il-1 alpha and tnf-alpha on phagocyte accumulation and murine antibacterial immunity. | il-1 and tnf both are reported to increase host antibacterial resistance. to directly compare their effects on tissue phagocyte accumulation and antibacterial activity, we infused recombinant human il-1 alpha and tnf-alpha into c3h/hej mice. although il-1, at a dose of 1 microgram/day, did not significantly elevate blood neutrophil concentrations, it increased the number of pmns within the spleen three to fourfold within 2 days. similar neutrophil accumulation also occurred in the lungs, bone ma ... | 1989 | 2789107 |
| treatment of mice with human recombinant interleukin-2 augments resistance to the facultative intracellular pathogen listeria monocytogenes. | the effects of exogenously administered human recombinant il-2 (hril-2) on resistance to listeria monocytogenes infection were examined. intravenous injection of hril-2 significantly enhanced antibacterial resistance in both bdf1 and c3h/hej mice. the beneficial effect of hril-2 was observed with as little as 0.6 micrograms per mouse, whereas optimum protection occurred at 6 micrograms per mouse, hril-2 was equally protective when administered concomitant with the listeriae or up to 24 h prior t ... | 1989 | 2789191 |
| spectrum and outcome of microbiologically documented listeria monocytogenes infections in cancer patients. | at the m.d. anderson cancer center (houston), listeria monocytogenes was cultured from 14 patients between 1980 and 1987. the case records of 11 of these patients were reviewed. underlying malignancies included acute leukemia (three), lymphoma (two), myeloma (one), adenocarcinoma of colon (two), carcinoma of breast (one), carcinoma of lung (one), and kaposi's sarcoma associated with the acquired immune deficiency syndrome (one). listeria monocytogenes was cultured from blood (eight patients), ce ... | 1989 | 2790706 |
| the influence of aluminum on resistance to listeria monocytogenes in swiss-webster mice. | female, adult swiss-webster mice were fed, during gestation and subsequent lactation, diets containing either 25 (control), 500 or 1,000 micrograms al/g diet in the form of al lactate, followed by challenge with listeria monocytogenes. mice in the groups fed 1,000 and 500 micrograms al/g had significantly lowered resistance to bacterial infection when compared to control animals (p less than 0.025). the animals given 1,000 micrograms al/g also had higher concentrations of liver al (p less than 0 ... | 1989 | 2793227 |
| symptomatic hydrocephalus and reversible spinal cord compression in listeria monocytogenes meningitis. case report. | central nervous system infections with listeria monocytogenes result in varied clinical syndromes ranging from meningitis to rhomboencephalitis. a case of listeria meningitis complicated by symptomatic communicating hydrocephalus and hydrostatic cervical cord compression is presented which clinically and radiographically improved with aggressive ventricular drainage. | 1989 | 2795184 |
| rhabdomyolysis and listeria monocytogenes. | non-traumatic rhabdomyolysis occurs as a complication of a wide variety of infections and is often discovered as a result of the associated renal failure. we report a case of meningitis due to listeria monocytogenes, an uncommon cause of infection in adults which was associated with rhabdomyolysis. this confirms a recent first case report of this association. | 1989 | 2799374 |
| the absence of direct antimicrobial activity in extracts of cytotoxic lymphocytes. | an important mechanism used by the immune system in resisting infections by intracellular pathogens is the destruction of host cells by cytolytic lymphocytes. whether these lymphocytes display a more direct antimicrobial action remains unclear. we have attempted to answer this question by testing extracts of cytolytic lymphocytes, prepared by cell fractionation, against three bacterial species - escherichia coli, salmonella typhimurium, and listeria monocytogenes. we also tested these extracts a ... | 1989 | 2807399 |
| activity of meropenem, against gram-positive bacteria. | a new carbapenem antibiotic, meropenem, was shown to be active against a large number of gram-positive bacteria. the drug inhibited penicillinase-positive and -negative, methicillin-susceptible staphylococci equally well. among the comparative antimicrobials examined, only n-formimidoyl-thienamycin (imipenem) was two to four times more active than meropenem. compared with vancomycin or methicillin, meropenem was 10-20 times more active. strains of 11 species of streptococci were highly susceptib ... | 1989 | 2808202 |
| comparative in-vitro activity of ly146032 and eight other antibiotics against gram-positive bacteria isolated from children. | ly146032, a cyclic peptide antibiotic active against many gram-positive bacteria, was compared to methicillin, vancomycin, clindamycin, cefuroxime and gentamicin against methicillin-resistant and methicillin-susceptible strains of staphylococcus aureus and staph. epidermidis. ly146032 was uniformly active against clinical isolates of staphylococci, inhibiting 90% of strains of staph. aureus and staph. epidermidis at a concentration of 0.5 mg/l. vancomycin was slightly less active than ly146032 a ... | 1987 | 2822647 |
| in-vitro activity of ly146032 against staphylococcus aureus, listeria monocytogenes, corynebacterium jk, and bacillus spp., in comparison with various antibiotics. | the in-vitro activity of ly146032 was studied against staphylococcus aureus, listeria monocytogenes, corynebacterium jk, and bacillus spp. in comparison with several agents with action against gram-positive bacteria. ly146032 showed an mic90 of 0.4 mg/l for s. aureus, regardless of the resistance to penicillin or oxacillin. ly146032 was equivalent in activity to ciprofloxacin and vancomycin against s. aureus and moderately active against other species tested (mic90, 0.8-3.2 mg/l). | 1987 | 2822648 |
| detection of hemolytic listeria monocytogenes by using dna colony hybridization. | a fragment of about 500 base pairs of the beta-hemolysin gene from listeria monocytogenes was used to screen different bacterial strains by dna colony hybridization. the cells in the colonies were lysed by microwaves in the presence of sodium hydroxide. of 52 different strains of listeria species screened, only the dna from beta-hemolytic (camp-positive) strains of l. monocytogenes hybridized with this probe. | 1987 | 2823710 |
| relationship of bacterial growth phase to killing of listeria monocytogenes by oxidative agents generated by neutrophils and enzyme systems. | listeria monocytogenes, a gram-positive motile bacterium which can cause severe bacterial infection in humans, is considered to be pathogenic by virtue of its ability to resist intracellular killing. since the mechanism of intracellular survival is poorly understood, we assessed the sensitivity of l. monocytogenes to several potent antibacterial products. phorbol myristate acetate (pma)-stimulated polymorphonuclear cells (pmns) produced extracellular antibacterial products which were inhibited c ... | 1987 | 2824383 |
| identification of the structural gene encoding the sh-activated hemolysin of listeria monocytogenes: listeriolysin o is homologous to streptolysin o and pneumolysin. | by immunoblotting with an antiserum raised against purified listeriolysin o, we have detected the presence of a truncated protein of 52 kilodaltons in culture supernatants of a tn1545-induced nonhemolytic mutant of listeria monocytogenes (j.l. gaillard, p. berche, and p. sansonetti, infect. immun. 52:50-55, 1986). the region of insertion of the transposon has been cloned and sequenced. the transposon had inserted in an open reading frame the listeriolysin o gene. the deduced amino acid sequence ... | 1987 | 2824384 |
| molecular analysis of bacterial cytolysins. | results of molecular and pathogenic studies of three different bacterial hemolysins (cytolysins) are presented. these exoproteins derive from the two gram-negative bacteria escherichia coli and aeromonas hydrophila and from the gram-positive pathogen listeria monocytogenes. the hemolysin of e. coli is determined by an 8-kilobase (kb) region that includes four clustered genes (hlyc, hlya, hlyb, and hlyd). this hemolysin determinant is part either of large transmissible plasmids or of the chromoso ... | 1987 | 2825323 |
| susceptibility of hrs/j mice to listeriosis: macrophage activity. | macrophage functions, including phagocytosis and bactericidal and oxidative activities, were measured in highly susceptible listeria monocytogenes-sensitive hrs/j homozygous and heterozygous mice. phagocytic studies with both caseinate-elicited and l. monocytogenes-immune macrophages revealed comparable engulfment of latex particles, zymosan, and bacteria by mononuclear phagocytes obtained from all experimental mouse strains. elicited macrophages cultivated from mutant hairless and heterozygous ... | 1988 | 2830193 |
| pharmacokinetic and in vivo studies with azithromycin (cp-62,993), a new macrolide with an extended half-life and excellent tissue distribution. | azithromycin (cp-62,993), a new acid-stable 15-membered-ring macrolide, was well absorbed following oral administration in mice, rats, dogs, and cynomolgus monkeys. this compound exhibited a uniformly long elimination half-life and was distributed exceptionally well into all tissues. this extravascular penetration of azithromycin was demonstrated by tissue/plasma area-under-the-curve ratios ranging from 13.6 to 137 compared with ratios for erythromycin of 3.1 to 11.6. the significance of these p ... | 1987 | 2830841 |
| effect of leukocyte and other tissue dialysates on nbt reduction and prostaglandin production in mice. | the effects of human leukocyte, porcine spleen and bovine liver dialysate fractions on listeria resistance were measured by survival studies and by assessing the capacity of peritoneal macrophages to produce superoxide anion (0-2) and prostaglandins. leukocyte (dle) and other tissue dialysates were fractionated on a sephadex g-10 column. thereafter the significant activities were found in fraction iii of dle, fraction ii of porcine spleen and fraction ii + iii of bovine liver dialysate. the trea ... | 1987 | 2831694 |
| serological investigations for some bacterial and viral pathogens in fallow deer (cervus dama) and wild boar (sus scrofa) of the san rossore preserve, tuscany, italy. | sera of 43 fallow deer (cervus dama) of the san rossore preserve (tuscany, italy) were examined for antibodies against eight pathogens; one proved positive for brucella sp., 21 for listeria monocytogenes, 34 for chlamydia psittaci, three for coxiella burnetii, one for infectious bovine rhinotracheitis virus, 11 for parainfluenza-3 virus, 25 for bovine viral diarrhea virus and six for bovine respiratory syncytial virus. no age and sex difference in the positivity rates and titers was evidenced, w ... | 1988 | 2832622 |
| role of hemolysin for the intracellular growth of listeria monocytogenes. | listeria monocytogenes insertion mutants defective in hemolysin production were generated using the conjugative transposons tn916 and tn1545. all of the nonhemolytic mutants (hly-) lacked a secreted 58-kd polypeptide, presumedly hemolysin, and were avirulent in a mouse model. an intracellular multiplication assay was established in monolayers of mouse bone marrow-derived macrophages, the j774 macrophage-like cell line, the cl.7 embryonic mouse fibroblast cell line, and the henle 407 human epithe ... | 1988 | 2833557 |
| tumor necrosis factor, alone or in combination with il-2, but not ifn-gamma, is associated with macrophage killing of mycobacterium avium complex. | organisms belonging to the mycobacterium avium complex (mac) are the most common bacterial pathogens in patients with aids but factors associated with the activation of cellular defense mechanisms against this atypical mycobacterium have not been defined. peritoneal macrophages harvested from a chronic mac infection in c57 black mice are able to kill approximately 86% of intracellular mac in contrast to 0 to 20% killing by unstimulated human and mouse macrophages in vitro. the availability of hu ... | 1988 | 2834450 |
| the pathology of aids. | the acquired immunodeficiency syndrome (aids) is a devastating new disease caused by the human immunodeficiency virus (hiv). this retrovirus causes profound immunoincompetence in its infected hosts, who are thereafter susceptible to develop myriad severe and relapsing protozoal, fungal, bacterial, viral, and arthropodal opportunistic infections, as well as unusual malignancies. the more than 50,000 patients who have developed aids in the united states have produced a sudden unexpected deluge of ... | 1988 | 2836878 |
| in vitro activities of azithromycin (cp 62,993), clarithromycin (a-56268; te-031), erythromycin, roxithromycin, and clindamycin. | the in vitro activity of azithromycin (cp 62,993 or xz-450) against haemophilus influenzae was greater than that of three other macrolides. however, azithromycin was four- to eightfold less active than erythromycin against the gram-positive cocci and against listeria monocytogenes. erythromycin and azithromycin were similar in their activity against legionella pneumophila, neisseria gonorrhoeae, neisseria meningitidis, and branhamella catarrhalis. | 1988 | 2840016 |
| [immunomodulating properties of salmozan and its effect on the functional activity of macrophages]. | the effect of salmozan on the resistance of mice to listeria monocytogenes infection, the formation of delayed hypersensitivity (dh) to sheep red blood cells in the animals, as well as changes in some functional activity characteristics of macrophages have been studied. the study has revealed that salmozan enhances anti-infectious resistance, suppresses the dermal manifestations of dh, and decreases the level of 5'-nucleotidase in peritoneal macrophages, stimulating their phagocytic activity. th ... | 1988 | 2842987 |
| the listeriolysin o gene: a chromosomal locus crucial for the virulence of listeria monocytogenes. | in culture supernatants of a tn 1545-induced non-hemolytic mutant of listeria monocytogenes, by immunoblotting with an anti-serum raised against purified listeriolysin o, we have detected the presence of a truncated protein of 52,000d (the secreted listeriolysin o is 60,000d). the region of insertion of the transposon has been cloned and sequenced. the transposon had inserted in an open reading frame. the homologies detected between this orf, streptolysin o and pneumolysin demonstrate the the tr ... | 1988 | 2843472 |
| gamma-interferon restores listericidal activity and concurrently enhances release of reactive oxygen metabolites in dexamethasone-treated human monocytes. | by preventing macrophages from destroying phagocytized microorganisms, glucocorticoids lower natural resistance of the host against many pathogens. gamma-interferon has an opposite effect and restores activity of dexamethasone-treated mononuclear phagocytes against some but not all microorganisms. in the present studies we show that dexamethasone impairs activity of human blood monocytes kept in culture for 36 h against listeria monocytogenes, without impairing h2o2 or o2- secretion. likewise de ... | 1988 | 2843576 |
| phosphatases activities in rabbit infected with listeria monocytogenes. | | 1987 | 2845337 |
| storage effects of sewage sludge cake on the survival of listeria monocytogenes. | sewage sludge cake is widely used as an agricultural fertilizer in iraq. listeria monocytogenes was shown to be present in small numbers in this material despite sewage treatments. in an attempt to reduce the numbers of this pathogen in this sewage end product, the survival of l. monocytogenes was monitored in a heap of sewage sludge cake stored for over 23 weeks on farm land. the organisms were reduced in numbers and eliminated to undetectable limits during 8 weeks of storage under subtropical ... | 1988 | 2852665 |
| enhancement of host resistance against listeria infection by lactobacillus casei: efficacy of cell wall preparation of lactobacillus casei. | cell wall, cytoplasm, polysaccharide, and peptidoglycan fractions prepared from lactobacillus casei, l. plantarum, and l. acidophilus were examined for their efficacies to enhance resistance of host mice against listeria monocytogenes infection. intraperitoneal injections of those cellular fractions of l. casei led to elicitation of inflammatory cells in the peritoneal cavity and the efficacy was highest in the case of peptidoglycan. macrophage ratio in the resultant peritoneal exudate cells was ... | 1988 | 2853287 |
| impairment of macrophage antiviral activity by soluble tumor products. effects of bacterial immunomodulators. | the antiviral activities of normal rat peritoneal macrophages versus herpes simplex virus type 1 were inhibited by sera from tumor-bearing rats and 3m kcl extracts of tumor mass. the inhibitory activity was demonstrated on the extrinsic as well as on the intrinsic macrophage functions. sera from corynebacterium parvum and listeria monocytogenes treated tumor bearing rats did not inhibit these macrophages functions. furthermore the 3 m kcl extracts from the tumor mass of the above treated tbr sho ... | 1988 | 2856293 |
| listeriosis. | | 1985 | 2863612 |
| modulation of the immune response to listeria monocytogenes by benzene inhalation. | benzene is a potent bone marrow toxicant. while all blood cell types are targets for benzene poisoning, lymphocytes are particularly sensitive. the immunotoxic consequences of benzene or its metabolites have been demonstrated in a number of in vitro studies; however, little data exist regarding the effects of benzene on host resistance to infectious agents. this investigation examined the effects of benzene on murine resistance to an infectious agent, listeria monocytogenes. four concentrations ... | 1985 | 2863880 |
| [the saprophytic phase in the ecology of the causative agents of infectious diseases]. | | 1985 | 2863907 |
| anti-bacterial immunity to listeria monocytogenes in allogeneic bone marrow chimera in mice. | protection and delayed-type hypersensitivity (dth) to the facultative intracellular bacterium listeria monocytogenes (l.m.) were studied in allogeneic and syngeneic bone marrow chimeras. lethally irradiated akr (h-2k) mice were successfully reconstituted with marrow cells from c57bl/10 (b10) (h-2b), b10 h-2-recombinant strains or syngeneic mice. irradiated akr mice reconstituted with marrow cells from h-2-compatible b10.br mice, [br----akr], as well as syngeneic marrow cells, [akr----akr], showe ... | 1986 | 2871109 |
| protection of mice against intestinal amoebiasis with bcg, corynebacterium parvum and listeria monocytogenes. | treatment with corynebacterium parvum or bcg, or infection with live listeria monocytogenes was found to protect mice against subsequent infection with entamoeba histolytica. complete protection was obtained in mice treated with 10(7) (colony forming units) of bcg but not with 10(5). partial protection was achieved with 10(6) of bcg. these data provide evidence that non-specific immunity plays an important role in the host defense against amoebic infection. | 1986 | 2880331 |
| analysis of colony-stimulating factors and macrophage progenitor cells in mice immunized against listeria monocytogenes by adoptive transfer. | experiments were performed to elucidate the role of colony-stimulating factors in host defenses to the intracellular pathogen listeria monocytogenes. mice were protected against listeria sp. by adoptive transfer of immune spleen cells and were then challenged with listeriae intravenously. control mice were injected with spleen cells from uninfected mice. adoptively immunized (immune) mice had significantly fewer listeriae in spleens and livers 2 and 4 days after listeria challenge than did contr ... | 1987 | 2886433 |
| listeriosis and food-borne transmission. | | 1988 | 2893892 |
| listeria in prepacked salads. | | 1988 | 2896986 |
| listeria in cook-chill food. | | 1988 | 2898633 |
| association of sporadic listeriosis with consumption of uncooked hot dogs and undercooked chicken. | in 1986-87 the centers for disease control conducted an active population-based survey of listeria monocytogenes infections in six regions of the united states. listeriosis was reported in 154 patients: one-third of cases were perinatal and the remaining two-thirds occurred in the elderly and immunosuppressed. 28% of cases were fatal. 82 cases and 239 controls matched for age and underlying disease were enrolled in a study of risk factors for listeriosis. cases were significantly more likely tha ... | 1988 | 2901619 |
| altered t-cell helper/suppressor ratio in mice chronically exposed to amyl nitrite. | | 1988 | 2902515 |
| materno-fetal listeriosis from cook-chill and refrigerated food. | | 1988 | 2903338 |
| transmission of listeria monocytogenes from mother's milk to her baby and to puppies. | | 1988 | 2903417 |
| cross-infection with listeria monocytogenes confirmed by dna fingerprinting. | | 1988 | 2903973 |
| purification, characterization and antimicrobial spectrum of a bacteriocin produced by pediococcus acidilactici. | an antimicrobial peptide designated pediocin ach was isolated from pediococcus acidilactici strain h. the pediocin ach was purified by ion exchange chromatography. the molecular weight of pediocin ach was determined by sds-page to be about 2700 daltons. pediocin ach was sensitive to proteolytic enzymes resistant to heat and organic solvents, and active over a wide range of ph. pediocin ach exhibited inhibition against several food spoilage bacteria and foodborne pathogens including staphylococcu ... | 1988 | 2906056 |
| listeriosis: new problems with an old pathogen. | | 1988 | 2907330 |
| microbiological evaluation of a hospital-delivered meals service using precooked chilled foods. | | 1988 | 2907341 |
| listeria monocytogenes sepsis from an infected indwelling i.v. catheter in a patient with aids. | | 1989 | 2911772 |
| corynebacterium aquaticum urinary tract infection in a neonate, and concepts regarding the role of the organism as a neonatal pathogen. | corynebacterium aquaticum urinary tract infection developed in a neonate 8 days after uncomplicated vaginal delivery. prior to definitive identification, the isolate was thought to be listeria monocytogenes because of its microscopic morphology, catalase positivity, and tumbling motility. the infant responded to intravenous ceftriaxone. because the presentation of c. aquaticum in this patient suggested systemic involvement, c. aquaticum may be regarded as a bona fide neonatal pathogen. | 1989 | 2915029 |
| listeria pneumonia. a case report. | a 42-year-old man with an atypical pneumonia. he had chest pain and a dry cough for 3 weeks, was dull at the left base clinically, and had left lower zone consolidation on chest radiography. the pneumonia spread despite oral ampicillin and cloxacillin. blood culture grew listeria monocytogenes and white cell count showed a monocytosis. he responded to intravenous penicillin and gentamicin with complete x-ray clearance. | 1989 | 2919343 |
| the c5-sufficient a/j congenic mouse strain. inflammatory response and resistance to listeria monocytogenes. | a/j mouse strain poorly responds to an inflammatory stimulus and is highly susceptible to listeria monocytogenes (lm) infection. this defect in the phagocyte inflammatory response caused by the c5 component of c deficiency was shown, by linkage analysis, to be the major reason for the extreme susceptibility of a/j mice to lm infection. the importance of this genetic defect in c5 in relation to the poor macrophage inflammatory response and to the susceptibility to lm infection was evaluated by de ... | 1989 | 2921523 |
| resistance to infection in murine beta-thalassemia. | clinical evidence suggests that individuals with chronic iron overload may be at increased risk of bacterial infection. we studied this question by using a unique model in which mice homozygous for a deletion in the gene encoding for the beta-major globin develop moderate anemia, splenomegaly, and tissue iron overload, a syndrome similar to beta-thalassemia in humans. mice heterozygous for the gene deletion were phenotypically normal. homozygous mice were significantly more susceptible to infect ... | 1989 | 2925237 |
| brainstem encephalitis due to listeria monocytogenes. favourable outcome after early antibiotic therapy. | a case of brainstem encephalitis is reported in which an early identification in blood of listeria monocytogenes allowed an effective antibiotic therapy (ampicillin and gentamicin) with complete recovery. | 1989 | 2925348 |
| listeria monocytogenes peritonitis: an additional case. | | 1989 | 2929577 |
| listeria monocytogenes spontaneous peritonitis. | | 1989 | 2929578 |
| migration of natural suppressor cells from bone marrow to peritoneal cavity by live bcg. | delayed-type hypersensitivity (dth) responses were suppressed in mice inoculated with bone marrow cells from mice that had been injected with 10(8) colony-forming units (cfu) of live bcg. upon analysis of this dth-suppression by the use of a macrophage migration inhibition (mi) assay, the in vitro correlate of dth, suppressor macrophages in the peritoneal cavity were found to play an important role in dth suppression. however, neither suppression of dth nor production of suppressor macrophages w ... | 1985 | 2933452 |
| [listeria monocytogenes encephalitis without meningitis. value of monitoring by cerebral x-ray computed tomography]. | | 1986 | 2935846 |
| synergy of ciprofloxacin and azlocillin in vitro and in a neutropenic mouse model of infection. | combinations of ciprofloxacin with azlocillin, piperacillin and ticarcillin were tested in vitro against clinical isolates. azlocillin plus ciprofloxacin showed synergy against 30% of pseudomonas aeruginosa isolates; it was either synergistic or additive against 78% of all isolates tested even those resistant to the beta-lactam. synergism was rarely noted for klebsiella pneumoniae, escherichia coli, enterobacter spp. or branhamella spp. isolates. minimum inhibitory concentrations of ciprofloxaci ... | 1986 | 2938945 |
| in-vitro activity of newer quinolones against aerobic bacteria. | nalidixic and five newer 4-quinolones, ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin were tested against 576 recent clinical aerobic bacterial isolates. the 4-quinolones were regularly active (mic90 less than 4 mg/l) against the following bacteria: staphylococcus aureus, s. epidermidis, s. saprophyticus, different enterobacteriaceae, haemophilus influenzae, campylobacter jejuni, pseudomonas aeruginosa, agrobacter spp., aeromonas spp., plesiomonas spp., neisseria meningitidis. ot ... | 1986 | 2940214 |
| why is listeria monocytogenes not a pathogen in the acquired immunodeficiency syndrome? | | 1986 | 2940988 |