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[the development of transfusion medicine (author's transl)].the development of transfusion medicine started from the attempts to transfuse blood in animals in the 17th century and the first fruits were seen in the second half of the 19th century. about 1800, however, blundell introduced a new development which brought fundamental changes with the elucidation of the problems of defibrination, the phenomenon of hemolysis and coagulation. at the beginning of the 20th century the serological problems were solved by landsteiner's discoveries. the introduction ...1979117327
[foundations of pharmacotherapy. clinical pharmacology in key words. drug testing 1]. 1979117334
[the relationship between fermentation and the morphological structure of rumen epithelium in sheep fed pelleted feeds].wethers were fed complete granular feed rations including 41.81% of grass hay, 25.28% of barley, 15.37% of sawdust, 14.98% of molasses, 1.32% of urea, and 1.24% of mineral supplement in dry matter for 24 weeks. samples of the dorsal rumen sac of these wethers were subjected to patho-anatomical, histological, histo-chemical, and electron-microscopical examination. volatile fatty acids were also determined in the rumen fluid of slaughtered animals. the control group was given the same diet in the ...1979117589
[detection of chlamydia by the immunofluorescence method].the possibility of detecting chlamydia by the direct immunofluorescence method was tested in the impression preparation of experimentally infected mice, chick embryos and naturally infected domestic mammals. in comparison with slight-microscope detection, this method was found to be sensitive and expedient. the greatest amount of antigen could be detected in the lungs of mice after intranasal infection already within 6 to 12 hours. in the other organs the findings were less ample; the visualizat ...1979117591
[therapy of domestic animals affected by alkylphosphates].sheep were studied for the possibility of treatment after parenteral (intramuscular) intoxication with edmm (methylthiophosphorous acid o-ethyl-s-2-dimethylamino-ethylester) and with edim (methylthiophosphorous acid o-ethyl-s-2-diisopropyl-aminoethylester). in both cases of intoxication, the therapy was based on a system of an anticholinergic and cholinesterase reactivator administered singly at a time of the maximum development of the clinical signs of poisoning and maximum inhibition of both e ...1979117593
the influence of specific antibodies and cellular immunity in the induction of tolerance of chemotactic activity caused by bacteroides fragilis lipopolysaccharide.exudate aspirated from wound chambers implanted subcutaneously on rabbits at different time intervals after local lipopolysaccharide (lps) injection, showed a peak of chemotactic mediator concentration in vitro about two hours before the peak of polymorphonuclear lekocytes accumulated in vivo was demonstrated. injection of lps locally into the wound chambers three days after the first injection of lps showed a reduced number of pmns accumulated in the exudate. antibodies to the lps preparation w ...1979117673
microimmunodiffusion test for diagnosis of ovine progressive pneumonia.two microimmunodiffusion tests (midt) for detection and measurement of ovine progressive pneumonia antibody are described. substrates of various salt concentrations and ph were used to determine the optimal conditions for the tests. in comparisons between two midt and one macroimmunodiffusion test, sera from cull ewes were used. the midt require less reagents and were more responsive than the macroimmunodiffusion test. after extended incubation of the test materials, results in all three tests w ...1979117729
gold-induced changes in the morphology and functional capabilities of human monocytes.the capacity of gold compounds to induce morphologic changes and alterations in the functional activity of human mononuclear phagocytes (m phi) in vitro was examined. human peripheral blood mononuclear cells were incubated with gold sodium thiomalate (25 microgram/ml) for 96 hours. as a result, m phi developed electron dense precipitates within phagolysosomes, as well as marked dilatation of these organelles. gold incubation also altered a number of m phi functions. while viability and adherence ...1979117813
ectopic calcification in lambs from feeding the plant cestrum diurnum.hypercalcemia and ectopic calcification were induced in 5 lambs by supplementing the diet with the dried leaves of the plant cestrum diurnum, for 8 to 9 weeks. lambs developed mineralization of blood vessels, heart, kidneys, and lungs. these tissues were examined by light and electron microscopy. in the vascular tissue there was calcification of elastic fibers in the hyperplastic intima and the media, along with mineralization of mitochondria of aortic smooth muscle cells. myocardial cells and t ...1979117888
thyroid function, iodine nutrition and fetal brain development. 1979117955
difference in hydrophobicity of human and animal iga. 1979117973
isolation and partial characterization of ovine lactoferrin.ovine lactoferrin was isolated by ammonium sulfate precipitation and ion exchange chromatography. comparative analyses were performed with the bovine protein. differences in the amino acid compositions and the tertiary structure of the proteins were observed.1979118050
detection of protein a-like substances on haemolytic streptococci prior to use in mixed reverse passive antiglobulin haemagglutination (mrpah).before mixed reverse passive antiglobulin haemagglutination tests (mrpah) can be used to measure the class of bacterial antibodies, the bacteria have to be shown to be free of protein a or protein a-like substances on their surfaces. two basic procedures have been examined: haemagglutination of red cells coated with immunoglobulin by the bacteria, and the mrpah reaction itself to reveal absorption of purified gamma fc by the bacterial suspension. the use of a purified gamma fc component has prov ...1979118215
b-complex genetic control of immune response to hsa, (t,g)-a--l, gt and other substances in chickens.immune response to poly-(l-tyrosine-l-glutamic acid)-poly-d,l-alanine-poly-l-lysine (t,g)-a--l), human serum albumin (hsa), and (l-glutamic acid50, l-tyrosine50)n (gt) was found to be linked to the b complex in an outbred line of leghorns segregating for the b1, b2, and b19 alleles. birds of the blood group genotypes b1b1, b2b2, and b19b19 were low, intermediate, and high responders, respectively to either (t,g)-a--l or hsa. response to gt, however, differed, with the b2b2 genotype being the onl ...1979118224
development of a radioimmunoassay for human seminal plasma inhibin.using a homogeneous inhibin preparation from human seminal plasma with a molecular weight of about 19 000, a sensitive and specific radioimmunoassay (ria) for inhibin has been developed. none of the purified hormones tested, such as lh, fsh and prolactin from different species, showed any cross-reaction in this ria. steroid hormones such as testosterone, dihydrotestosterone, oestradiol-17 beta and progesterone did not interfere with the assay. the antiserum had an affinity constant (ka) of 2.379 ...1979118250
bioassays for inhibin: a critical review. 1979118252
studies on purification and characterization of sheep testicular inhibin. 1979118253
immunobiology of schistosomiasis.although malaria and hookworm disease appear to be on the decline, another dreaded parasitic disease-schistosomiasis-is on the increase. presently, the number of infected individuals with schistosomes is estimated to be 250 million, and even though only a small proportion of them become sick and die, schistosomiasis remains a medical problem of great significance. the high incidence of infection of man with schistosoma mansoni, schistosoma japonicum or schistosoma haematobium, as well as the chr ...1979118264
a practicable immunological approach to block spermatogenesis without loss of androgens.the intrinsic capacity of the immune system to elicit immune response selectively against late developing sperm proteins has been mobilized to intercept spermatogenesis. bacillus calmette-guérin given in appropriate doses intratesticularly is effective in bringing about this effect. in dogs and rhesus monkeys, the sperm count in the semen declined precipitously, and almost complete azospermia was attained in 4-6 weeks after immunization. the few sperm cells that were present were immotile. exami ...1979118455
[listeria enzootic in newborn lambs].epizootological, clinical and pathomorphological studies were made of a meningo-encephalitic form of listeriotic enzooty in new born lambs. the clinical symptoms as well as the patho-anatomical and patho-histological changes in the brain and in the inner organs of dead lambs were described. arisal of enzooty was connected with the inclusion of silage in the daily ration of ewes. it was assumed also that infection of suckling lambs possible by the milk of diseased mother-ewes also and in the pren ...1979118579
pathways of arachidonic acid metabolism. 1979118659
longitudinal studies of naturally acquired brucella abortus infection in sheep.naturally acquired brucella abortus infections were studied during consecutive pregnancies in eight sheep and in their lambs over a period of 40 months to evaluate epizootiologic aspects of natural infection in sheep. brucella abortus was isolated from the ewes following 16 of 26 natural terminations of pregnancy: from 5 of 6 ewes in the first year, from six of eight ewes in the second year, from two of six ewes in the third year, and from three of six ewes in the fourth year. vaginal swab sampl ...1979118693
immunodiagnosis of hydatidosis using monospecific immune serum anti ag5.microdouble diffusion technique using whole hydatid antigen and monospecific antiserum against echinococcus genus-specific antigen 5 was applied to the diagnosis of human hydatid disease. the use of this simple and economical method may be extended to the specific diagnosis of parasitic diseases.1979118777
[existence of several non-specific recognition systems in macrophages].rat peritoneal cells were made to bind five particle species: immunoglobulin-coated sheep red cells, glutaraldehyde-treated sheep red cells, latex beads, leishmania and tumor cells. the dependence of binding on various physico-chemical parameters was studied. the binding of latex beads or leishmania was not inhibited by cold (4 degrees c), sodium azide, cytochalasin b and ethyleneglycol or dimethylsulphoxide. the binding of immunoglobulin-coated sheep red cells was unaffected by cold and azide, ...1979118824
binding of serum amyloid p-component (sap) by amyloid fibrils.serum amyloid p-component (protein sap) was found to bind in vitro to isolated amyloid fibrils of both primary and secondary types. the binding was strictly calcium-dependent, optimal uptake requiring at least 0.5 mm calcium ion. using normal human serum as the source of protein sap different fibril preparations became saturated with between 5--20 micrograms of sap per mg dry weight of fibril. isolated pure protein sap bound in greater amounts. in control experiments sap did not bind significant ...1979118839
toxicologic studies with sheep fed colored magazines and newsprint.paper containing colored inks from magazines and newspapers was fed as 23% of their ration to sheep for 175 days. a similar ration containing oat hulls in place of the paper was fed to control animals. the paper-fed animals consumed 29% more feed than the controls but the feed efficiency (kg animal weight gained/kg ration consumed) of the two rations was approximately equivalent. lead contained in the paper accumulated in animal tissues. hepatic microsomal mixed function oxidase activity was sev ...1979118844
comparative aspects of the brain growth spurt. 1979118862
the action of chelating agents and local anesthetics on the terminal stages of immune hemolysis. 1979118922
in vitro production of a biologically active fab2-like fragment by digestion of human igg rheumatoid factor with human polymorphonuclear leukocyte elastase. 1979118923
serodiagnosis of ram epididymitis by counterimmunoelectrophoresis, using brucella ovis surface r antigen.the counterimmunoelectrophoresis (cie) technique was developed as a diagnostic procedure for ram epididymitis caused by brucella ovis. cie test results with sera from naturally and experimentally infected male sheep compared favorably with those obtained by gel diffusion and complement fixation employing the same b. ovis surface r antigen. the main advantage of cie over gel diffusion consists in a significant reduction of the time required to detect precipitin formation, whereas both methods obv ...1979118983
attachment of antigens and antibodies to fixed red cells: their use in rosette and haemagllutination tests: a comparison with fresh red cells. 1979119160
[effect of intravenous glycine infusions on the plasma amino acid level of sheep]. 1979119379
effects of prostaglandin f2 alpha on blood constituents and certain hormones in najdi sheep. 1979119380
alterations of the cell surface morphology in human t-rosetting lymphocytes. an ultrastructural study.a study of e-rosette ultrathin sections has been undertaken in an attempt to analyze changes induced during the t-lymphocyte-sheep red blood cell interaction on the rosetted lymphocyte surface architecture. the formation of nonimmune rosettes implies different types of attachment between lymphocytes and sheep red blood cells which can affect the rosetted lymphocyte surface morphology: (a) junctions not involving morphological changes which correspond to bands or point-to-point contact sites. (b) ...1979119410
contribution of protozoa to the rumen cellulolytic activity. 1979119466
hydrolytic activities of rumen ciliates. 1979119467
role of rumen protozoa in the digestion of food cellulosic materials. 1979119468
ciliate implantation in the rumen: influence of inoculated genus and type of diet. 1979119469
amino acid requirements for microbial protein synthesis. 1979119470
protein fermentation and growth by rumen microbes. 1979119471
the net utilization of inorganic sulphur by rumen microbes. 1979119472
estimation of microbial protein in duodenal digesta. 1979119474
rumen digestion parameters in lambs fed with pelleted diet. 1979119477
characterization of stable conformational variants of erythrocyte carbonic anhydrases.limiting viscosity numbers of bovine and ovine erythrocytes carbonic anhydrase variants were calculated by the objective method of comparing viscosimetric data obtained from low-activity-human erythrocyte carbonic anhydrase and its natural variant. shifts of mobilities and isoelectric points are shown for all species variants, but variations of limiting viscosity numbers were only detected for human and bovine variants. results of the study are consistent with the observation that variants arise ...1979119551
continuous transcutaneous oxygen tension measurements in experiments with juvenile rhesus monkeys and pregnant ewes. 1979119559
an apparent "activation" of prostaglandin synthetase by preincubation with arachidonic acid [proceedings]. 1979119660
plaque forming cell assay to measure responses in mice to the random copolymer (glu60phe40).a plaque-forming cell (pfc) assay to measure the immune response of mice to the synthetic random copolymer of glutamic acid and phenylalanine (gphe) is described here. gphe can be coupled to sheep red blood cells (srbc) using "aged" crcl3. both igm and igg plaques are detected in the murine gphe response. mice of h-2 haploytpes p and q are high responders, a and k are medium or low responders and b, d and s are nonresponders as detected by the pfc assay.1979119705
estimation of half-life and metabolic clearance rate of thyrotropin-releasing hormone in sheep using a double antibody radioimmunoassay. 1979119785
electron-microscopic studies on theileria ovis rodhain, 1916: development of kinetics in the gut of the vector tick, rhipicephalus evertsi evertsi neumann, 1897, and their transformation within cells of the salivary glands.gamogony of theileria ovis rodhain occurs within the gut of nymphs of the tick rhipicephalus evertsi evertsi neumann. after molting, spherical and ovoid parasites are found within the intestinal cells of the ticks. these stages are thought to be zygotes, because they undergo a transformation process leading ultimately (in 3 days) to the formation of a motile stage, the kinete, the fine structure of which is very similar to that of the ookinetes of the hemosporidia. the kinete leaves the gut cell ...1979119849
studies on sarcocystis species iii: the macrocystic species of sheep. 1979119933
effect of increased levels of urea in the diet on ruminal protozoal counts in four ruminant species. 1979120355
pathogenesis of mouse scrapie: dynamics of agent replication in spleen, spinal cord and brain after infection by different routes. 1979120379
sarcocystis transmitted by blood transfusion.merozoites were found in blood smears from calves, lambs, and pigs exhibiting signs of acute sarcocystosis after oral infection with sporocysts of sarcocystis bovicanis, sarcocystis ovicanis, and sarcocystis suihominis. in each of 3 experiments, whole blood containing merozoites was transfused from an infected host to 2 uninfected recipients of the same species; 2 additional animals of the same species served as uninfected nontransfused controls. the bovine, ovine, and porcine donors all died of ...1979120435
differentiation of coital behavior in mammals: a comparative analysis.the evidence reviewed suggests that in all mammalian species the adult male's ability to display masculine coital behavior depends in part on exposure of the developing brain to testicular testosterone or its metabolites. in many mammals, particularly rodents, ruminants, and some carnivores, perinatal exposure to androgen also causes behavioral defeminization, i.e., reduced capacity to display typically feminine coital behavior in response to gonadal hormones in adulthood. the data reviewed sugg ...1979120519
the prevalence of sarcocytis spp in dogs, foxes and sheep and toxoplasma gondii in sheep and the use of the indirect haemagglutination reaction in serodiagnosis.sporocysts of sarcocystis spp were found in the faeces of 39.3 per cent and 25 per cent of farm dogs and foxes respectively. the indirect haemagglutination serodiagnostic test suggested that nearly all sheep in the area sampled became infected early in life and diagnosis of infection by this means correlates well with trichinoscopy findings. the sarcocystis antigens used in serodiagnostic tests did not cross react with sera positive for toxoplasma gondii. sarcocystis antigens derived from cattle ...1979120576
[differentiation of nonspecific serological reactions in brucellosis].differentiation of non-specific agglutination was performed by the complement binding reaction, coombs' reaction, hajdu reaction, the surface fixation and agglutination reaction and the reaction of complement binding with heterologic antigens. for that purpose the following were used: 1) serums--antiglobulin against cattle globulin, 5720 serum of various animals which had manifested non-specific agglutination with brucella antigen and brucella serums of experimentally infected sheep, of naturall ...1979120633
comparison of two methods of preparing enzyme-antibody conjugates: application of these conjugates for enzyme immunoassay. 1979120684
pituitary response of prepuberal lambs to oestradiol-17 beta.in two experiments 48 prepuberal merino ewe lambs were injected with oestradiol-17 beta (e2) or saline to study the effect of e2 on their plasma lh levels and on oestrus and ovulation. in the three groups which received 30 (experiment i), 50 and 30 (experiment ii) microgram e2 respectively, 27 out of 28 lambs showed an lh response, the corresponding mean lh peaks being 64.3 +/0 22.5, 153.6 +/-33.4 and 91.7 +/- 16.9 ng/ml at mean intervals of 11.1, 11.2 and 10.5 h, respectively, after injection. ...1979120739
[effect of progesterone on male and female sex behavior induced by steroid hormones in adult ovariectomized ewes].ovariectomized adult ewes daily treated with i/m injections of testosterone propionate (10 mg/day) or oestradiol benzoate (200 microgram/day) show male-like sexual behaviour and simultaneously a permanent female receptivity. additional daily treatment with 100 mg of progresterone results in a rapid decrease in male sexual responses both when ewes are treated with testosterone and with oestradiol. no effect is observed on the female receptivity. cyproterone acetate (100 mg/day) given to ewes in a ...1979120792
progesterone. 1979120841
testosterone, testosterone oenanthate and testosterone propionate. 1979120842
indirect hemagglutination test for detection of antibody to rickettsia rickettsii in sera from humans and common laboratory animals.antibody production in humans and three species of laboratory animals infected with rickettsia rickettsii was determined with the indirect hemagglutination test. rabbits, guinea pigs, and mice were inoculated with r. rickettsii and bled at intervals. antibody which agglutinated both fresh and glutaraldehyde-fixed sheep erythrocytes sensitized with antigen prepared either from purified rickettsiae or from infected yolk sacs was found in rabbit sera at all intervals tested (10 to 59 days postinfec ...1979120875
serological properties of cellular and extracellular glycerol teichoic acid antigens of streptococcus mutans.cell-free supernatant of streptococcus mutans cultures was concentrated by 50% ammonium sulphate precipitation to 1/50 of the original culture volume. most extracellular glucosyltransferase activity was detected in the supernatant. furthermore, the supernatant reacted with serotype specific antiserum, showing immunological identities with the serotype specific polysaccharide antigen obtained from whole cells by hot saline or naoh extraction in double diffusion tests. immunoelectrophoretic analys ...1979120923
gravity, metabolic rate and body size of mammals. 1979120950
[sporulation of anthrax bacilli].studies on bac. antharcis sporulation were carried out. by modifying the medium of kim et al., it was proven that 10 out of the 13 bac. antharcis strains studied sporulated until the 72d h more than 99%. the remaining 3 strains sporulated more slowly. it was established that the nutrient medium could not ensure optimal sporulation conditions for all strains. the fact that the capsuleless vaccine "ihtiman" sporulates 100% at the 24th to the 48th h is of considerable importance. the cultivation of ...1979120996
[current tests for the "in vitro" immunologic exploration in man].several "in vitro" methods are developed to study cellular immunity as same as study of antibodies in humoral immunity exploration. the more used in human pathologics are the enumeration of thymus-derived (t) lymphocytes by the formation of nonimmune rosettes e with sheep erythocytes and bone marrow (b) lymphocytes by the presence of membrane-bound immunglobulins; the detection of lymphocyte activation by measuring proliferation (lymphocyte transformation); the mixed lymphocyte reaction, the ela ...1979121050
hexachlorobenzene (hcb): a review. 1979121077
inhibin: from concept to reality. 1979121176
in vivo activation of murine peritoneal macrophages by nocardia water soluble mitogen (nwsm).in vitro nwsm has been shown to be a b cell mitogen and a polyclonal activator. although nwsm has been also shown to be adjuvant active in vivo, motogenicity and polyclonal activation are not observed when this fraction has been administered to mice. in contrast, the experiments reported here demonstrate that after in vivo administration several effects of nwsm on mouse peritoneal macrophages can be observed: nwsm was able to induce an important increase in the ability of peritoneal macrophages ...1979121200
the immunodepressive effect of phenol derivatives. 1979121202
physicochemical and comparative studies on bile proteins. 1979121295
[passage of thiamine (vit. b 1) through the rumen wall of sheep in vivo]. 1979121505
[increased catabolism of antigen and enhanced recruitment of antigen-sensitive cells by activation of macrophages with a bacterial phospholipid extract (ebp) (author's transl)].intravenous (iv) infection of a bacterial phospholipid extract (ebp) 24 h before iv immunization of mice with sheep red blood cells has modified the specific immune response. a decrease of the response evaluated by the number of rosette-forming cells was observed after the larger doses of ebp. this effect appeared secondarily to an increased catabolism of antigen. infection of a medium sized dose of ebp directly into the portal vein induced a decreased response by enhancing antigen phogocytosis ...1979121519
inhibition of prostaglandin biosynthesis by eicosapentaenoic acid.eicosapentaenoic acid [20 : 5 (n-3)] is not oxidized by the purified cyclooxygenase from sheep vesicular glands in the conditions of low peroxide tone in which arachidonate [20 : 4 (n-6)] is rapidly oxygenated. when the level of peroxide in incubation mixtures is allowed to rise, there is a dramatic change in reactivity of the cyclooxygenase to react with 20 : 5 (n-3) at one-halt the rate and one-third the extent observed with 20 : 4 (n-6). overall, the low peroxide levels expected in vivo would ...1979121610
effects of taste aversion conditioning on the primary antibody response to sheep red blood cells and brucella abortus in the albino rat. 1978121817
studies of pre- and postimmunization antibodies of sheep.serum samples were taken serially from three nonimmunized sheep over a long period of time. antibodies to human serum albumin (hsa), ovalbumin (oa) and fitc were separated from the samples. than, two of the animals were injected with hsa+ complete freund's adjuvant, the third with adjuvant without antigen. serial postimmunization serum samples were subjected to the same procedures as the pre-immunization ones. the specific antibodies increased in concentration, and only the postimmunization anti ...1979121873
a comparative electrophoretic analysis of mammalian carbonic anhydrase isozymes: evidence for a third isozyme in red skeletal muscles.1. starch gel electrophoretic patterns of carbonic anhydrase (ca) isozymes were examined from tissue extracts of cats, sheep, rabbits and mice. 2. in addition to the widely distributed and extensively studied b and c isozymes, an additional isozyme (called ca-a) was observed. 3. tissue distribution studies showed the a isozyme to be predominantly localized in red skeletal muscles, although this activity was also observed in white and "mixed" skeletal muscles of the cat, sheep and rabbit, as well ...1977122577
lithium metabolism and intracellular electrolytes.lithium chloride was administered orally to swine and two different types of sheep, hk and lk. there was a pre-lithium 16-fold variation in intracellular sodium (lk greater than hk greater than swine) and a 6.5-fold variation in the intracellular potassium (swine greater than hk greater than lk). collected plasma and erythrocytes were analyzed for lithium, sodium and potassium. the ratio of erythrocyte lithium/plasma lithium was directly related to the pre-lithium erythrocyte sodium concentratio ...1978122706
the arterial circle of the base of the brain and its feeding vessels in certain mammals. 1977122731
transplantation of lymphoid cells into immunodeficient chickens. dissociation in the reconstitution of b and t cell functions. 1975122790
xenograft rejection in human beings. 1975122872
the suppressive effect of immunization on the proliferative responses of rat t cells in vitro.dna synthesis (3h-thymidine incorporation) of da rat spleen and lymph node cells cultured with pha or (da x lewis)f1 lymph node cells was profoundly inhibited by pretreatment with large i.v. doses of antigen (greater than 100 mg oa or greater than 10(10) srbc) 24 hr before culture. this effect, seen as early as 3 to 6 hr after antigen administration, had disappeared within 7 days. similar depressed spleen cell responses were seen 9 days after footpad injection of 200 mug oa in complete adjuvant. ...1975122987
[the development of the larvae of the sheep nasopharyngeal botfly, oestrus ovis l. (diptera, oestridae)].in order to find out factors affecting the presence of two generations of o. ovis in the southern parts of its distribution area there were conducted regular measurements of the body length of the ist instar (3718 specimens) and weight of the iind and iiid instar larvae (1460 specimens). these observations were carried out in two herds of sheep in low-lying and foothill zones of aserbaijan. statistical analysis has shown the following: a) the growth inhibition, which is especially distinct in au ...1975123057
a preliminary report on the use of a chronic peritoneal fistula for endoscopic examination of ovine ovarian activity.a description is given of a technique devised to allow repeated endoscopic observations to be made of ovarian changes occurring during an oestrus cycle in the ewe. the use of a chronic peritoneal fistula is illustrated and the methods used to maintain its patency discussed. the technique was carried out in a small number of ewes and the ovarian changes occurring in an ovary of one of these ewes, over a 22 day period, are shown in photographic and diagrammatic form.1975123105
[eradication of sheep foot rot on a state farm]. 1975123107
effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe.the fetoplacental unit of the ewe is capable of increasing the biosynthesis of estrogens following the exogenous administration of dhea to the fetus. the maximum concentrations of estrogens appeared approximately 30 minutes after the administration of dhea. uterine blood flow in the pregnant ewe increased approximately 90 minutes after the maximum concentrations of estrogens were noted. the administration of dhea to the nonpregnant, ovariectomized ewe did not elicit estrogen biosynthesis or chan ...1975123121
effect of pinealectomy, gonadectomy, pcpa and pineal extracts on the rat parvocellular neurosecretory hypothalamic system; a fluorescence histochemical investigation.using the fluorescence histochemical technique, yellow autofluorescent granules were observed in neurones of the arcuate and ventromedial hypothalamic nuclei of the rat (type i cells). in the same nuclei, neurones could be demonstrated showing a formaldehyde-induced yellow fluorescence (type ii cells). microelectrophoresis and special staining methods applied to the pineal gland revealed the autofluorescent compound to be a protein containing a relatively high content of tryptophan. it is probab ...1975123166
a potent antimitogenic factor from group a streptococci.a cytoplasmic component from group a streptococci produced complete suppression of human lymphocyte transformation induced by phytohaemagglutinin or the mixed lymphocyte reaction in vitro. it also suppressed antibody-forming cells in mice against sheep erythrocytes. the active substance was eluted as second and third fractions form sephadex g-200 chromatography of the 100,000 g supernatant of sonically ruptured group a streptococci. the antimitogenic activity was not susceptible to trypsin, pron ...1975123216
the allogeneic effect: m-locus differences substitute for differences in the h-2 major histocompatibility complex.the primary immune response against sheep red blood cells in t cell-deficient spleen cell cultures from nude mice was tested in the absence and presence of allogeneic spleen cells. the allogeneic spleen cells differed either in regard to the major histocompatibility complex (h-2) or only with respect to the m-locus. surprisingly the m-locus different spleen cells were almost as efficient in enhancing the anti-sheep red blood cell response in nude cultures as were the cells differing on the compl ...1975123260
functional heterogeneity among the t-derived lymphocytes of the mouse. iv. nature of spontaneously induced suppressor cells.when spleen cells are cultured for 4 days in the presence of fetal bovine serum, t-cells are generated which nonspecifically suppress the humoral responses of non-precultured cells to a variety of antigens. these t cells can be generated from both short-lived, sessile t1 cells and long-lived, recirculating t2 cells, and thus appear similar to suppressor t cells activated by concanavalin a.1975123261
the function of the disc of the temporomandibular joint.a study of the structure of the discs of the temporomandibular joints of three mammals showed marked differences among them. since the animals selected had different basic patterns of mastication, it may be that each disc has become modified to different functions in different mammals.1975123275
the reactivity of derivatives of digoxin and digitoxin as measured by the na-k-atpase displacement assay and by radioimmunoassay.derivatives of digoxin and digitoxin were measured by the na-k-atpase displacement assay and by radioimmunoassay and the data compared with biological potency of these compounds. there was a slightly higher affinity of digoxigenin-bis-digitoxoside as compared with digoxin using digoxin-specific antiserum and considerably less affinity of digoxigenin and dihydrodigoxin than the parent compound in the same system. a similar trend was observed for the derivatives of digitoxin using digoxin-specific ...1975123547
temperature regulation.the general way of looking at short-term temperature regulation has not fundamentaly changed since 1968. some points nevertheless have been developed and deserve special attention: 1. the influence of water on the skin surface inhibits sweat secretion (55, 106). this fact may be the explanation of sweating fatigue and of discordant conclusions regarding the functioning of the regulator, particularly during exercise in man. 2. since a large number of studies have shown that appropriate behaviors ...1975123725
inhibitory effect of normal mammalian sera on the rosette formation of human lymphocytes with sheep red blood cells. 1975123840
stimulation of b-immunocytes by a t-cell factor produced in mixed leukocyte cultures. 1975124153
macrophage metabolism during phagocytosis and digestion of normal and igg antibody-coated sheep erythrocytes.the respiration rate, aerobic glycolysis and glycolytic enzyme activities of purified mouse peritoneal macrophages increase during phagocytosis of either free or antibody-coated srbc. these changes, however, seem to be roughly parallel to the amount of phagocytized antigen. in the digestive phase, ag-ab complexes induce more marked changes in macrophage metabolism than a comparable amount of free antigen. lactate production, activity of several glycolytic enzymes and alanine-aminotransferase as ...1975124249
phosphofructokinases from porcine liver and kidney and from other mammalin tissues. 1975124390
preliminary characterization of the cell in nu/nu mice that responds in the mixed leukocyte reaction. 1975124639
immunofluorescent localization of glycogenolytic and glycolytic enzyme proteins and of malate dehydrogenase isozymes in cross-striated skeletal muscle and heart of the rabbit.specific antisera against glycogen phosphorylase, phosphofructokinase, aldolase, glyceraldehyde-phosphate dehydrogenase, enolase, lactate dehydrogenase, cytosolic and mitochondrial malate dehydrogenase from rabbit muscle were obtained from sheep. the gamma-globulins were used for indirect immunofluorescent localization of the respective enzymes in rabbit skeletal muscle and heart. in stretched skeletal muscle a cross-striation like distribution was observed for all enzymes studied. in the case o ...1975124716
suspected "b"-vitamin deficiency of sheep fed a protein-free urea containing purified diet. 1975124720
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