| humoral and cell-mediated immune response to influenza virus. ii. experiments in ferrets. | | 1982 | 6188342 |
| studies on pathogenicity and immunogenicity of cold adapted variants of influenza virus. | cold adapted variants of influenza virus, replicated at 37, 35, 33 and 30 degrees c, were tested for capability to multiply in ferrets and to induce h and n antibodies. virus grown at 30 degrees c differed from the other in electrophoretic mobility of its polypeptides in page, in inducing higher level of n antibodies, and in higher intensity of immunofluorescence reaction in the respiratory tract. | 1982 | 6189378 |
| persistence of visna virus in cultured ferret brain cortex and fibroblasts. | cerebral cortex tissue fragments from newborn ferrets have been cultured in vitro and, when exposed to visna virus, failed to exhibit a cytopathic effect but retained the genome of the virus in a quiescent state for 46 d before synthesizing plaque-forming virus for the subsequent 26 d. in contrast, infection of an established line of cells derived from a ferret's brain with visna virus resulted in the formation of the polykaryocytes typically produced by this virus and a limited synthesis of pla ... | 1983 | 6189779 |
| surveillance of influenza in houston, texas, usa: gradual transition from a/victoria/75 (h3n2) to a/texas/77 (h3n2) predominance and antigenic characterization of "intermediate" strains. | influenza epidemics in houston, texas, usa, during the winters of 1975-76, 1976-77, and 1977-78 were attributed to a/victoria/3/75 (h3n2), b/hong kong/5/72, and a/texas/1/77 (h3n2)-like viruses, respectively. both a/victoria and a/texas viruses were detected towards the end of the 1976-77 epidemic and throughout the 1977-78 epidemic. to determine if there had been a gradual transition in the predominant strain, 267 viral isolates from the 1975-76 epidemic were tested for a/texas virus. eight spe ... | 1983 | 6190585 |
| the early development of the av node and bundle in the ferret heart. | the development of the atrioventricular (av) junctional tissues in the ferret embryonic heart was studied on days 16, 18, and 21 of gestation. this important region of the heart was examined with pas and toluidine-blue staining at the light microscope level and with transmission electron microscopy at the ultrastructural level. by day 16 of gestation the ferret heart was in the initial stages of convolution. the heart was at the primitive four-chamber stage by 18 days postcoitum. on day 21 of ge ... | 1983 | 6192697 |
| heterogeneity of influenza b viruses. | antigenic analysis of influenza b strains isolated in 1981-82 from england, japan, and the usa, using a panel of monoclonal antibodies to the haemagglutinin of b/oregon/5/80, showed considerable heterogeneity among the isolates, the majority of which had distinct reactivity patterns. antigenically similar viruses were isolated from england, japan, and the usa, and heterogeneity was detected among isolates from each country. further studies are needed to determine whether this marked heterogeneit ... | 1983 | 6194912 |
| identification of the binding sites to monoclonal antibodies on a/ussr/90/77 (h1n1) hemagglutinin and their involvement in antigenic drift in h1n1 influenza viruses. | we have determined nucleotide sequences of the ha1 portion of the hemagglutinin (ha) gene of the parental a/ussr/90/70 (h1n1) virus and its eight variants selected in vitro with six monoclonal antibodies to study antigenic determinants. the ha1 gene of one of the variants (b-1-23) was cloned in bacteria and its nucleotide sequence was determined by the maxam-gilbert method. the nucleotide sequence of the variant was confirmed by the dideoxy chain termination method. the gene sequences of the oth ... | 1983 | 6196912 |
| immunohistochemical localization to pyloric antral g cells of peptides derived from porcine preprogastrin. | antibodies to the peptides (designated cryptic a and b) that flank the g34 region of pig progastrin were used in immunohistochemical studies of the gastrointestinal tract. in elution and restaining experiments, the same cells were revealed by the cryptic peptide antibodies, and by antibodies specific for c-terminus of g17 and n-terminus of g34. the cells reacting with the cryptic peptide antibodies were localized predominantly to antral mucosa. they were found in pig, ferret, dog and cat but not ... | 1984 | 6208575 |
| characterization of h2 influenza virus hemagglutinin with monoclonal antibodies: influence of receptor specificity. | antigenic analysis of human and avian h2 influenza viruses were done with monoclonal antibodies to the ha molecules in hemagglutination inhibition (hi) assays. these studies revealed that the receptor-binding specificity of the hemagglutinin can markedly influence the antigenic analysis obtained with monoclonal antibodies in hi tests. influenza viruses that are sensitive or resistant to inhibition by horse serum inhibitors showed marked differences in their reactivity with monoclonal antibodies ... | 1984 | 6208682 |
| steroid metabolism in the corpus luteum of the ferret. | implantation in the ferret is believed to be induced by a luteal substance which acts in concert with progesterone (p4) and which is secreted sometime between days 6 and 8 of pregnancy. this experiment was designed to identify the steroid products synthesized by ferret corpora lutea (cl) on these 2 days of pregnancy. cl were dissected from ferrets on day 6 or 8 of pregnancy and incubated with [3h] pregnenolone (p3), [3h] p4, or [3h] dehydroepiandrosterone (dhea). controls with no tissue or with ... | 1983 | 6228262 |
| steroid metabolism in corpora lutea of the western spotted skunk (spilogale putorius latifrons). | the present study reports steroid metabolism by corpora lutea (cl) obtained from skunks with diapausing embryos ('delay' cl) and with activated embryos (activated cl). cl from both reproductive periods were incubated with various radioactive precursors. control incubations without any tissue or with 50 microliter of packed skunk blood cells were also conducted simultaneously. incubation of skunk cl with [3h]-pregnenolone for 3 h resulted in 36% of the precursor accumulating as progesterone. meta ... | 1984 | 6239920 |
| experimental models for study of common respiratory viruses. | numerous epidemiological studies have shown that there is excess respiratory disease morbidity in areas of high atmospheric pollution, implying an interactive effect on the clinical illness associated with these common infections. the principal etiologic agents of human respiratory infections are respiratory syncytial virus (rsv), influenza viruses (iv), parainfluenza virus types 1 and 3 (p1, p3), adenoviruses (ad), rhinoviruses (rv) and mycoplasma pneumoniae (mpn). understanding the pathogenesi ... | 1980 | 6250807 |
| isolation of a paramyxovirus from the cerebrospinal fluid of a dog with posterior paresis. | a paramyxovirus was isolated from cerebrospinal fluid of a dog with a history of incoordination and posterior paresis. the virus apparently was not related to canine distemper virus (cdv), considering the lack of virus neutralization with cdv-specific antibody, negative immunofluorescence with cdv-specific conjugate, and avirulence for ferrets. the virus was antigenically related to a prototype strain of canine parainfluenza virus, as determined by positive immunofluorescence with canine parainf ... | 1980 | 6254938 |
| survey of virally mediated permeability changes. | 1. sendai virus causes permeability changes when added to freshly isolated brain cells (cerebellum or ependymal cells) or to a culture of forebrain cells. 2. sendai virus causes permeability changes when added to organ cultures of ferret lung or nasal turbinate. influenza virus causes no permeability changes under these conditions. 3. rabies virus and vesicular-stomatitis virus, in contrast with sendai virus, do not cause permeability changes in bhk cells or lettrée cells. 4. serum from patients ... | 1980 | 6258574 |
| [suitability of ferrets for the ibr-ipv vaccine efficacy evaluation]. | | 1981 | 6274304 |
| field and laboratory studies of equine influenza viruses isolated in 1979. | experimental ponies developed signs of disease four days after the intranasal instillation of a/england 1/79 equine influenza virus and virus was recovered from the nasopharynx from the second to the ninth day. no significant antigenic difference was found between the virus and the prototype a/miami 1/63 virus, using post infection ferret and chicken sera and post vaccination pony sera. no antigenic differences were found between four viruses isolated between january and july 1979, although some ... | 1981 | 6275599 |
| antiviral effects of single-stranded polynucleotide inhibitors of the influenza virion-associated transcriptase against influenza virus infection of hamsters and ferrets. | administration of a single-stranded polynucleotide copolymer containing 9% cytidine residues and 91% 4-thiouridine residues [poly(c,s4u10)], a known potent inhibitor of the virion transcriptase of influenza viruses, suppressed the amount of virus recoverable from the nasal washes of influenza virus-infected hamsters and ferrets. the incidence of sneezing and nasal discharge in infected ferrets was also reduced. in hamsters, poly(c,s4u10) was more effective than amantadine-hcl or virazole. polyin ... | 1981 | 6280608 |
| effects of butoprozine on ionic currents in frog atrial and ferret ventricular fibres. comparison with amiodarone and verapamil. | the effects of butoprozine on cardiac membrane currents of frog atrial and ferret ventricular fibres were investigated in voltage clamp conditions by means of the double sucrose gap technique. comparison was made with amiodarone and verapamil. butoprozine was found to decrease the fast sodium and slow calcium inward currents and the delayed outward current in a dose-dependent manner. the reactivation kinetics of both inward currents were reduced by butoprozine. amiodarone principally decreased t ... | 1982 | 6280628 |
| failure to detect hemagglutination-inhibiting antibodies with intact avian influenza virions. | avian influenza viruses replicate in a variety of mammals and birds, yet hemagglutination inhibition tests show that postinfection sera from these animals (e.g., ferrets and ducks) have insignificant levels of antibodies (hinshaw et al., infect. immun. 34:354-361, 1981). this suggested that avian influenza viruses, in contrast to mammalian viruses, may not induce a significant humoral response. studies reported here indicate that avian influenza viruses do induce high levels of antibodies in fer ... | 1982 | 6292104 |
| enhancement of calcium current during digitalis inotropy in mammalian heart: positive feed-back regulation by intracellular calcium? | 1. effects of digitalis compounds on slow inward ca current i(si)) and contractile force were examined in ferret ventricular muscle (single sucrose-gap voltage clamp) and calf purkinje fibres (two micro-electrode voltage clamp).2. in ventricular muscle, ouabain increased i(si) and inward current tails associated with i(si) conductance. the enhancement of i(si) followed a time course similar to the development of the positive inotropic effect, and it could be observed in the absence of aftercontr ... | 1982 | 6292410 |
| pulmonary alpha-adrenoceptors: autoradiographic localization using [3h]prazosin. | we determined the distribution of pulmonary alpha-adrenoceptors by autoradiographic localisation of [3h]prazosin binding to frozen sections of ferret lung. specific binding of [3h]prazosin to lung sections was saturable and of high affinity (kd = 0.44 +/- 0.55 nm; mean +/- s.e., n = 5), with a specificity indicating binding to alpha 1-receptors. autoradiographic showed that alpha 1-receptors were present in highest density in vascular smooth muscle (small vessels greater than large vessels), and ... | 1983 | 6303807 |
| diltiazem and verapamil preferentially block inactivated cardiac calcium channels. | diltiazem has been proposed to act by blocking calcium channels of cardiac and smooth muscle since it has pharmacological [12-14] and clinical [10] effects that resemble those of verapamil, an agent that has been shown to block these channels [3]. however, block of the slow inward current by diltiazem has not been directly demonstrated. in fact, it has been suggested that diltiazem has an entirely different mechanism of action [7]. we therefore studied the blocking effects of diltiazem and verap ... | 1983 | 6304329 |
| autoradiographic localization of autonomic receptors in airway smooth muscle. marked differences between large and small airways. | autoradiographic methods were used to determine the distribution of autonomic receptors in airway smooth muscle of ferret from trachea to terminal bronchioles; [3h]dihydroalprenolol, [3h]prazosin, and [3h]quinuclidinyl benzilate were used to label beta-adrenergic, alpha-adrenergic, and muscarinic receptors, respectively, using experimental conditions that gave maximal specific receptor binding. marked differences were found in the longitudinal distribution of each receptor and in distribution of ... | 1983 | 6305241 |
| neutral red stains ganglia in the vagal motor pathway to ferret trachea without affecting ganglionic transmission. | to determine the effect of neutral red (0.01%) on neural transmission through ganglia, we used an in vitro nerve-muscle preparation of ferret trachea. before, during, and after incubating the trachea in neutral red, we induced isometric muscle contractions first by activating preganglionic fibers with electrical stimulation of the vagus nerve, and then by activating postganglionic nerve fibers with electrical field stimulation. incubation in neutral red (0.01%) for 45 min at 38 degrees c reduced ... | 1983 | 6308359 |
| involvement of dopaminergic neurotransmission in the control of goal-directed movements. | changes produced in dopamine (da) activity, by administration of the da-antagonists metoclopramide (10 mg/kg im) and tiapride (16 mg/kg im) and of the da agonists apomorphine (0.5 and 1 mg/kg im) and bromocriptine (8 mg/kg orally), specifically modified predatory behavior in the ferret. sulpiride (40 mg/kg ip and 90 mg/kg im) did not change the behavior. the number of bites necessary to kill the prey was reduced by metoclopramide and tiapride. the number of bites after the death of the prey was ... | 1983 | 6312482 |
| transmission in airway ganglia of ferrets: inhibition by norepinephrine. | we examined the possibility that norepinephrine inhibits transmission in parasympathetic ganglia of the ferret trachea. we impaled ganglion cells on recording microelectrodes and evoked postsynaptic action potentials by stimulating fiber tracts entering the ganglion. when norepinephrine was added to the recording bath, the action potentials were blocked. phentolamine reversed this block. these results indicate that, by activating alpha-receptors, norepinephrine inhibits transmission in airway ga ... | 1983 | 6316214 |
| mapping of adrenergic receptors in the trachea by autoradiography. | we investigated the distribution of adrenergic receptors in ferret trachea using autoradiography. [3h]dihydroalprenolol, used to identify beta-adrenoceptors, revealed a high density of specific binding sites over surface epithelium and submucosal glands, with less labelling of smooth muscle. [3h]prazosin labelling showed that alpha 1-receptors were numerous in glands and epithelium, but sparse in smooth muscle. comparison of adrenergic receptor densities in tracheal sections from the same animal ... | 1983 | 6317370 |
| the sympathetic superior cervical ganglia as "little neuroendocrine brains". | the superior cervical ganglia (scg) provide sympathetic innervation to the pineal gland, cephalic blood vessels, the choroid plexus, the eye, carotid body and the salivary and thyroid glands. removal of the ganglia brings about several neuroendocrine changes in mammals, including the disruption of water balance in pituitary stalk-sectioned rats and the alteration of normal photoperiodic control of reproduction and thyroid function in hamsters, ferrets, voles, rams and goats. these effects are co ... | 1983 | 6324543 |
| ephaptic impulse transmission between ventricular myocardial cells in vitro. | impulse transmission between closely appositioned cylindrical myocardial preparations , from the ferret, was studied in vitro. one preparation was driven, and when the longitudinal extracellular potential difference between electrodes 80 micrometers apart was made larger than 30-60 mv by increasing the resistance of the extracellular space, ephaptic (i.e. non synaptic) impulse transmission from one preparation to another occurred. in 2 out of 8 pairs of preparations examined the impulse transmis ... | 1984 | 6331073 |
| antigenic comparisons of swine-influenza-like h1n1 isolates from pigs, birds and humans: an international collaborative study. | the objective of this international collaborative study was to compare recent swine isolates of influenza viruses and determine whether significant antigenic differences among isolates from different areas of the world could be detected. h1n1 viruses isolated from pigs, birds and humans in 12 different countries were compared in haemagglutination-inhibition assays with post-infection ferret sera and monoclonal antibodies to h1n1 strains. using a/nj/8/76 as the reference strain, we found that rec ... | 1984 | 6335845 |
| distribution of viral antigen with the lower respiratory tract of ferrets infected with a virulent influenza virus: production and release of virus from corresponding organ cultures. | using fluorescent antibody techniques, a semi-quantitative survey has been made of the distribution of influenza virus antigen in the trachea, main bronchi, and three zones (hilar, intermediate and alveolar) of all four lung lobes of ferrets following intranasal inoculation of a virulent clone (7a) of the recombinant influenza virus a/pr/8/34-a/england/939/69 (h3n2). the results confirm the indications from our previous quantitative surveys of infectious virus and histological damage in these ar ... | 1983 | 6338151 |
| studies of two novel sulfasalazine analogs, ipsalazide and balsalazide. | sulfasalazine appears to exert its beneficial effect in colitis by releasing 5-aminosalicylic acid in the colon, but its use can be limited by side effects. ipsalazide and balsalazide are novel sulfasalazine analogs designed to release 5-aminosalicylic acid and a nontoxic carrier molecule in the gastrointestinal tract. they have a low oral toxicity following single or repeat administration to mouse, rat, and ferret, and balsalazide is not mutagenic in the ames test. ipsalazide and balsalazide ar ... | 1983 | 6345112 |
| normal and abnormal appearances of the 35-day ferret fetus studied by freehand (razor blade) sections and gross examination. | this communication reports the sectioning and subsequent examination of 1-mm freehand razor blade sections of the normal 35-day ferret fetus; pregnancy in the ferret lasts for 42 days. skeletal and other abnormalities obtained after maternal treatment with teratogens, such as trypan blue, mustine hydrochloride, and sodium salicylate are included for comparison with the normal. | 1983 | 6348990 |
| pericentriolar processes of photoreceptor cell basal bodies in the mammalian retina. | pericentriolar processes (arm-like fibers) of the migrating centrioles (diplosome) in differentiating retinal photoreceptor cells were examined in six mammalian species (hamster, vole, rat, rabbit, ferret, cat). these processes emanate in a radial fashion from one end of the centrioles comprising the photoreceptor diplosome. the pericentriolar processes of the basal body are first observed as the diplosome migrates toward the apical plasmalemma, suggesting that centrioles are committed early-on ... | 1983 | 6356667 |
| clinical trials with canine distemper vaccines in exotic carnivores. | two types of killed canine distemper virus (cdv) vaccine and a modified-live cdv vaccine were clinically evaluated in four species of exotic carnivores. in 16 trials in which 13 red pandas (ailurus fulgens) were given the killed vaccine, only 1 animal had a virus-neutralization titer that exceeded 1:100. a red panda given modified-live cdv vaccine deemed safe for gray foxes and ferrets died of bacterial pneumonia 16 days later. there was no pathologic evidence of canine distemper in that panda. ... | 1983 | 6358163 |
| mastitis caused by hemolytic escherichia coli in the ferret. | hemolytic escherichia coli was isolated from the mammary glands of 8 ferrets with gangrenous mastitis. clinical signs included firm swelling of one or more mammary glands and discoloration of the overlying skin. peracute disease and acute septicemia were observed, and in some cases the animals rapidly became moribund. antibiotic therapy alone did not alter the course of the disease. wide surgical resection of the involved glands in combination with systemic antibiotic therapy (ampicillin 10 mg/k ... | 1983 | 6358164 |
| intra- and interspecific embryo transfer. | the procedures that are collectively referred to as embryo transfer (et) have many uses. they were first used as research tools to study fetal-maternal physiology. since the first successful mammalian embryo transfer in 1890, et has been utilized for enhancement of genetic selection; diagnosis and treatment of infertility; control of infectious disease transmission; screening for genetic defects; propagation of rare and endangered species; and the study of developmental biology. most of the embr ... | 1983 | 6363609 |
| the role of cellular susceptibility in the declining severity of respiratory influenza of ferrets with age. | a comparison was made, both in vivo and in organ culture, between newborn (1-day-old) and suckling (15-day-old) ferrets of lower respiratory tract tissue infected with a virulent strain (clone 7a) of influenza virus. newborn ferrets were killed by influenza virus following intranasal inoculation but suckling ferrets were almost as resistant as adult ferrets. in newborn ferrets there was a rapid, severe and progressive infection of lung tissue with infection of alveolar cells as well as those of ... | 1984 | 6365145 |
| biosynthesis of lhrh: inferences from immunocytochemical studies. | inferences regarding biosynthesis of lhrh in rats are made from immunocytochemical studies using lhrh antisera with varied and specific binding requirements. immunoreactive perikarya were observed with antisera that could bind putative large molecular weight precursors of lhrh. no cells were detected with an antiserum that requires free decapeptide terminals and could not bind extended precursors. no such differential immunoreactivity was apparent in neuronal processes and neurovascular terminal ... | 1983 | 6369270 |
| immunocytochemical localization of lhrh in the median eminence, infundibular stalk, and neurohypophysis. evidence for multiple sites of releasing hormone secretion in humans and other mammals. | the distribution of luteinizing hormone-releasing hormone (lhrh) was studied by light-microscopic immunocytochemistry in the hypothalamo-pituitary complex of humans, monkeys, ferrets, bats, and rats. lhrh-immunoreactive fibers were identified in the median eminence of all these species, but the precise location of these fibers varied. in rats, the vast majority of lhrh fibers in the median eminence was confined to the external zone. in contrast, in bats, most of the lhrh fibers were located in t ... | 1984 | 6370455 |
| suppression and enhancement of transformation of ferret peripheral blood mononuclear cells by mycobacteria. | the effect of heat killed mycobacterium bovis on the phytohaemagglutinin (pha) response of normal peripheral blood leucocytes from ferrets was dose dependent. concentrations of 10(6) organisms ml-1 and below enhanced the response, whereas more than 10(6) organisms ml-1 suppressed it. this suppression correlated with cytotoxicity of m bovis for ferret peripheral blood leucocytes. three environmental strains, m phlei, m smegmatis and m aurum were not cytotoxic and did not affect the pha response b ... | 1984 | 6379787 |
| lhrh neurons and their projections in humans and other mammals: species comparisons. | using light microscopic immunocytochemistry, we have identified lhrh neurons and their projections in humans, monkeys, ferrets, bats and rats. in all these species, lhrh neurons project to the vascular contact zone of the me, but positions of perikarya vary. this cell population, confined largely to rostral forebrain regions in rats, expands into the medial basal hypothalamus in humans, rhesus monkeys, ferrets and bats. accompanying this expansion is an augmentation of extrahypothalamic lhrh pro ... | 1984 | 6384949 |
| [intestinal influenza infection in ferrets]. | | 1984 | 6397158 |
| the effects of changes of ph on intracellular calcium transients in mammalian cardiac muscle. | the calcium-sensitive photoprotein aequorin was micro-injected into cells of rat, ferret, rabbit and cat papillary muscles. aequorin light emission is a function of free intracellular calcium concentration. the changes in intracellular calcium concentration [( ca2+]i) and tension accompanying changes of ph have been studied. when the solution perfusing the papillary muscle was changed from tyrode solution equilibrated with 5% co2 to tyrode solution equilibrated with 15% co2, developed tension sh ... | 1983 | 6410050 |
| carbonic anhydrase activity of intact erythrocytes from seven mammals. | carbonic anhydrase activity of intact erythrocytes from seven mammalian species was determined at 25 degrees c, ph 7.4, by mass spectrometry using the 18o-exchange technique. the seven species were cavia porcellus, mustela putorius furo, felis domesticus, canis familiaris, homo sapiens, equus caballus, and bos taurus. carbonic anhydrase activities determined as a function of hemoglobin concentration (std kcat) for intact erythrocytes at ph 7.4 were not significantly different from those determin ... | 1983 | 6415018 |
| an immunohistochemical study of the middle ear muscles of some carnivores and primates, with special reference to the iim and slow-tonic fibre types. | the middle ear muscles of several species of carnivores (cat, dog, fox, ferret and stone-marten) and some new world monkeys (callithrix, saimiri) and old world monkeys (cercopithecus, macaca) were examined. the fibre type compositions of these muscles were determined by a combination of the standard histochemical myofibrillar atpase method, and immunohistochemical techniques using myosintype-specific antisera. immunohistochemically slow-tonic fibres were found in the stapedius muscles of only tw ... | 1983 | 6415024 |
| study of prolactin levels in the ferret. | a radioimmunoassay for canine prolactin has been used to measure prolactin in the ferret. serial dilutions of extracts of ferret pituitary glands and of ferret plasma yielded curves that were parallel with the canine prolactin standard curve. the sensitivity, accuracy, reproducibility and precision of the assay were within acceptable limits. plasma prolactin levels increased after the administration of thyrotrophin releasing hormone (trh) or chlorpromazine, but not after giving luteinizing hormo ... | 1983 | 6417258 |
| half-life of fsh and lh in the ferret. | anoestrous and oestrous ferrets were injected with luteinizing hormone-releasing hormone (lrh) or a long-acting analogue and subsequently hypophysectomized. spayed ferrets were hypophysectomized without prior treatment with gonadotrophin releasing factor, and serial blood samples collected from all animals in order to follow the rate of decline in plasma gonadotrophin concentration. the half-life of lh in the spayed female (around 2 h) was much longer than that of the hormone released from the h ... | 1984 | 6421040 |
| in vitro activation of the promutagens 2-acetamidofluorene, cyclophosphamide and 7,12-dimethylbenzanthracene by constitutive ferret and rat hepatic s-9 fractions. | the ability of the ferret to metabolically activate promutagenic compounds was compared with that of the rat, using the salmonella/microsome assay. three compounds which require biotransformation to mutagenic metabolites, 2-acetamidofluorene (2-aaf), cyclophosphamide (cpa), and 7,12-dimethylbenzanthracene (dmba), were studied. metabolic activation was provided by ferret or rat hepatic s-9 fractions at 5 levels for each chemical, and optimal s-9 levels as well as dose-response curves were obtaine ... | 1984 | 6427977 |
| cutaneous mastocytoma in a ferret. | | 1984 | 6432756 |
| description of sarcocystis falcatula stiles, 1893, a parasite of birds and opossums. | sarcocystis falcatula stiles, 1893 is re-described. intermediate hosts of the parasite which was earlier described as sarcocystis debonei vogelsang, 1929 are species of passeriform, psittaciform, and columbiform birds. in these birds, muscle zoites are 6.88 x 2.19 (4.8-8.4 x 1.2-3.6) micron and are enclosed in a cyst wall with regular protrusions, 1-5 micron long. the convoluted primary wall has multiple thin areas in the osmiophilic layer. microtubules originate in the ground substance and exte ... | 1984 | 6439855 |
| preconditioning of trichinella spiralis nativa larvae in musculature to low temperatures. | preconditioning of a trichinella spiralis nativa isolate in ferret and fox musculature was carried out by freezing at -15 degrees c from 0 to 322 days prior to low temperature refrigeration at -32 degrees c. a limited number of preconditioned samples of infected fox musculature was also refrigerated at -45 degrees c. preconditioned larvae were appreciably more resistant than those subjected to the low temperatures directly. under the conditions of this investigation, the longer the period of pre ... | 1984 | 6441341 |
| oestrogen production by blastocyst and early embryonic tissue of various species. | oestrogen synthesis by the early embryo in vitro was studied with tissue from pigs, sheep, cows, roe deer, ferrets, cats, rabbits and a plains viscacha. definitive evidence for aromatase activity and oestrogen synthesis in preimplantation trophoblast was obtained for the pig with the formation of oestrone, oestradiol-17 beta and oestradiol-17 alpha from 3h-labelled androstenedione and dehydroepiandrosterone. aromatase activity was appreciably lower in all other species studied, and labelled oest ... | 1980 | 6448924 |
| mucosubstances in the colonic goblet cells of the ferret. | mucosubstances in the colonic goblet cells of the ferret (putorius [mustela] furo) were studied histochemically. they contained predominantly sulphated mucosubstances in the proximal colon and only sulphated mucosubstances in the distal colon. the sulphated mucosubstances were of weakly acidic nature. some deep cells and a few superficial cells in the proximal colon contained sialomucins which were sialidase-sensitive. neutral mucosubstances were not found in the colon. | 1981 | 6455896 |
| eeg and seizure threshold in normal and lissencephalic ferrets. | changes in eeg and susceptibility to electrically induced seizures were examined in the ferret with lissencephaly produced by exposure to a single injection of methylazoxymethanol acetate (mam ac) given to the pregnant jill on gestation day 32. ten lissencephalic and 11 normal ferrets were chronically implanted with 14 cortical stainless steel electrodes. eeg records were sampled from various stages of the sleep/awake cycle. six of each group were subjected to electrical stimulation for seizure ... | 1984 | 6466999 |
| hypoxic pulmonary vasoconstriction during steady and pulsatile flow in ferrets. | we examined the effects of hypoxia and pulsatile flow on the pressure-flow relationships in the isolated perfused lungs of fitch ferrets. when perfused by autologous blood from a pump providing a steady flow of 60 ml/min, the mean pulmonary arterial pressure rose from 14.6 to 31.3 torr when alveolar po2 was reduced from 122 to 46 torr. this hypoxic pressor response was characterized by a 10.1-torr increase in the pressure-axis intercept of the extrapolated pressure-flow curves and an increase in ... | 1984 | 6469782 |
| mapping of cortical histogenesis in the ferret. | the columnar organization of forebrain cortical neuron production allows the neuroepithelium to be analysed in terms of a simple growth model. the pattern of neuron release within each column is repeated with great regularity across the surface of the developing cerebral hemisphere, resulting in the accumulation of cortical neurons in radial stacks above the proliferative ventricular epithelium. the time course of recruitment of adjacent tissue into neuron production accounts for the observed ro ... | 1984 | 6470609 |
| angiotensin ii does not inhibit vagally-induced bradycardia or gastric contractions in the anaesthetized ferret. | the effects of angiotensin ii (aii) and the analogue sar1-leu8-angiotensin ii on the changes in heart rate and gastric pressure induced by vagal stimulation were investigated in the urethane-anaesthetized ferret. aii at high doses (500 ng kg-1 i.v.) increased blood pressure and decreased gastric pressure whereas sar1-leu8-aii at the same dose had a much smaller effect on blood pressure and no effect on gastric pressure. intravenous injections or infusions of aii or its analogue did not alter the ... | 1984 | 6478113 |
| altered auditory brainstem evoked responses in the ferret model for reye's syndrome. | the effects of influenza b, aspirin and hyperammonemia on the functional integrity of the cochlea were examined using the ferret model for reye's syndrome. auditory brainstem evoked responses (abr) were recorded from treated ferrets and compared to those recorded from controls. delayed latencies of all waves, as well as increased i-iv interwave latencies were observed in recordings from treated ferrets. importantly, the latencies of wave i, nerve generator potential from the eighth nerve, and wa ... | 1984 | 6480231 |
| nitrate balance and biosynthesis in the ferret. | the net biosynthesis of nitrate in the ferret was demonstrated to be 8.89 to 10.3 mumol/kg bw/day. nitrate balance studies indicated that, because of metabolism, excretion of nitrate was lower than ingestion when oral doses were higher than 6.3 mumol/day. at nitrate ingestion levels of less than 6.3 mumol/day, excretion exceeded intake. studies with 15n-labeled nitrate indicated that only 36% of the oral dose was recoverable as [15n]nitrate from urine. oral doses of 15n-labeled ammonia resulted ... | 1984 | 6485022 |
| the role of lung development in the age-related susceptibility of ferrets to influenza virus. | newborn (i-day-old) ferrets died following intranasal inoculation of influenza virus (clone 7a) but suckling (15-day-old) ferrets were almost as resistant as adult ferrets. many of the deaths in newborn ferrets were consequent upon an increased lower respiratory tract infection. one reason for the latter was an increase in susceptibility of both ciliated epithelium and alveolar cells in newborn ferret lungs when compared with the corresponding cells in adult and suckling ferrets (coates et al. 1 ... | 1984 | 6487534 |
| coronary microangiography in the guinea pig, rabbit and ferret. | using improved methods, we have developed a microangiographic technique for studying the coronary circulation in langendorff perfused guinea pig, rabbit and ferret hearts. striking anatomical differences were observed between these species. in the guinea pig, the interventricular septum was supplied by a large septal artery which always arose from the right coronary artery, whereas in the rabbit and ferret, the septal artery was smaller and originated from the left coronary artery. the circumfle ... | 1984 | 6490209 |
| fetal alcohol syndrome in the ferret (mustela putorius). | gastric intubation of 1.5 g ethanol/kg maternal body weight produced a significant teratogenic response in ferrets (mustela putorius) treated once daily from gestational days 15 through 35. this response was evident by a rise in the frequency of fetuses with one or more malformations (21%), and by a rise in the frequency of litters with one or more malformed fetuses (50%). palatoschisis and greater relative intermedial canthi distance observed in this study are diagnostic features of the fetal a ... | 1984 | 6495223 |
| the effects of shortening on myoplasmic calcium concentration and on the action potential in mammalian ventricular muscle. | when cardiac muscle shortens during a contraction, the duration of mechanical activity is abbreviated (shortening deactivation), but the duration of the action potential is prolonged. neither of these phenomena is fully understood, but both may be related to changes in the myoplasmic free calcium concentration. in these experiments, isolated papillary muscles from cats and ferrets were allowed to contract under various mechanical conditions while myoplasmic calcium was monitored with aequorin, o ... | 1984 | 6499137 |
| effect of neonatal gonadectomy and administration of testosterone on coital masculinization in the ferret. | male ferrets castrated on postnatal day 5 displayed significantly lower levels of neck gripping, mounting, and pelvic thrusting behavior than groups of males castrated on postnatal days 20 or 35 when tested in adulthood after treatment with testosterone (t). administering a high dosage of t via sc silastic capsules to ovariectomized female ferrets over postnatal days 5-20 caused a significant enhancement of all three parameters of masculine coital behavior and ossification of clitorides, in comp ... | 1984 | 6499776 |
| the histology and ultrastructure of the meyers-kouwenaar body in ferrets infected with brugia malayi. | a study was made of the meyers-kouwenaar (mk) body in the livers of experimentally infected ferrets. meyers-kouwenaar bodies, the carcasses of microfilariae (mff) covered by deposits of splendore-hoeppli (sh) material, were found in small abscesses of eosinophils and in granulomas. the sh deposits varied from an eosinophilic, hyaline fringe around intact mff to multilayered deposits surrounding an unrecognizable granular remnant. in abscesses, peroxidase activity was intense in sh deposits and t ... | 1984 | 6507726 |
| choice of calcium salt. a comparison of the effects of calcium chloride and gluconate on plasma ionized calcium. | equimolar quantities of calcium chloride and calcium gluconate produced similar changes in plasma ionised calcium concentration when injected intravenously into anaesthetised ferrets or when added to human blood in vitro. in vivo changes were followed with a calcium electrode positioned in the animal's aorta, and this showed that the ionisation of calcium gluconate on its first pass through the circulation is as great as that of calcium chloride. this does not support the common suggestion that ... | 1984 | 6507824 |
| effects of influenza infection, aspirin, and an arginine-deficient diet on the inner ear in reye's syndrome. | the individual effects of an influenza b viral infection, aspirin, and an arginine-deficient diet on the inner ear were assessed in the ferret model for reye's syndrome using both functional and morphological parameters. auditory brainstem evoked responses recorded from inoculated ferrets revealed threshold elevations and increased latencies during the first 72 hours, but approximated those of control animals by 96 hours. although there was a mild distention of reissner's membrane, no pronounced ... | 1984 | 6508126 |
| the anatomy of the ferret paratracheal parasympathetic nerve-ganglion plexus. | silver-impregnated preparations of the ferret paratracheal nerve-ganglion plexus were studied for description and quantitation of the general morphology of ganglia and nerve bundles and trunks. most ganglia were found in one or two chains, separated by interganglionic nerve trunks, running the length of the trachea in close apposition to the trachealis muscle. ganglia were flat, one cell deep, and characterized by irregular spacing and small and variable numbers of perikarya. perifascicular, inf ... | 1984 | 6510374 |
| hormonal correlates of photoperiod-induced puberty in a reflex ovulator, the female ferret (mustela furo). | in an attempt to develop an animal model wherein the pubertal process could be initiated or accelerated by a readily controlled, noninvasive, external signal, this study examined sexual development of the female ferret, a photoperiodic, reflex ovulator. these animals exhibit signs of precocious sexual maturation within 6 wk of exposure to a stimulatory, long-day photoperiod at 15 wk of age. in the first study, females matured under a long-day stimulus were allowed to mate with a fertile male fer ... | 1984 | 6518233 |
| comparison of monoclonal antibodies with ferret sera for the characterization of influenza a (h3n2) virus strains in a computer system. | a panel of murine monoclonal antibodies was generated against five different influenza a (h3n2) virus strains, isolated between 1977 and 1980. monoclonal antibodies with defined specificities in haemagglutination inhibition tests for the strains against which they had been raised were selected. eventually 18 of these were chosen and tested against a large number of recent h3n2 isolates. the results were compared with those obtained with antisera from ferrets immunized with the five strains menti ... | 1984 | 6526140 |
| mucormycotic meningoencephalitis in a ferret (case report). | | 1984 | 6527482 |
| histology of the ferret retina. | the retina of the adult ferret, mustelo furo, was studied with light and transmission electron microscopy to provide an anatomical basis for use of the ferret as a model for retinal research. the pigment epithelium is a simple cuboidal layer of cells characterized by a zone of basal folds, apical microvilli, and pigment granules at various stages of maturation. the distinction between rod and cone photoreceptor cells is based on their location, morphology, heterochromatin pattern and the electro ... | 1984 | 6529018 |
| effects of dietary hexachlorobenzene exposure on regional brain biogenic amine concentrations in mink and european ferrets. | in the initial trial, adult mink and ferrets were administered hexachlorobenzene (hcb) via the feed at concentrations of 1, 5, or 25 ppm for 47 wk. animals receiving 125 and 625 ppm hcb in the diet died before termination of the experiment, with female ferrets at the 125 ppm level displaying abnormal aggressiveness and hyperexcitability just prior to death. hypothalamic serotonin (5-ht) was significantly elevated at all dose levels in mink, and cerebellar 5-ht was significantly elevated at 1 ppm ... | 1984 | 6542146 |
| adrenergic and cholinergic receptors in submucosal glands of the ferret trachea: autoradiographic localization. | | 1983 | 6578099 |
| does almitrine bismesylate improve v/q matching? an animal study. | pulmonary vascular actions of almitrine bismesylate were studied in ferrets, rats, cats and dogs in conditions which simulated those of patients with hypoxic lung disease. all or part of a lung was made hypoxic or hypoventilated so that affected vessels were constricted. rats were made chronically hypoxic (10%, o2, normobaric chamber). in vivo and isolated preparations were used. in all preparations and species almitrine bismesylate caused vasoconstriction in normoxia, constriction followed by d ... | 1983 | 6586435 |
| periapical response to apical plugs of dentin and calcium hydroxide in ferret canines. | | 1984 | 6586964 |
| analysis of antigenic variation in equine 2 influenza a viruses. | influenza outbreaks involving viruses of the h3n8 subtype (equine 2) often occur in vaccinated horses. for this reason, a series of influenza viruses of the h3n8 subtype were examined to determine if antigenic variation could be detected in isolates during the period 1963-81. antigenic analyses with post-infection ferret sera and monoclonal antibodies showed that the haemagglutinins of recent isolates were antigenically distinguishable from the prototype a/eq/miami/1/63 and that antigenically di ... | 1983 | 6601538 |
| the utilization of exogenous taurine for the conjugation of xenobiotic acids in the ferret. | although the occurrence of the taurine conjugation mechanism for various xenobiotic acids is well established, nothing is known of the source of the taurine used for this conjugation. [14c]taurine was administered alone and in combination with 2-naphthylacetic acid or clofibric acid (both of which are known to form taurine conjugates) to to ferrets, and the 0--24 h urine collected. of the dose of [14c]taurine, 26% was recovered in the urine in 24 h and the only 14c-containing material present wa ... | 1983 | 6613158 |
| free fatty acids in an animal model of reye's syndrome. | recent studies have indicated that viral infections, aspirin treatment and hyperammonemia are associated with reye's syndrome. it has also been reported that free fatty acids in serum and total lipids in the liver of reye's syndrome patients are elevated during illness. the role of the lipid changes in the development of the disorder cannot be optimally studied in human patients, because infection and aspirin ingestion occur prior to the earliest symptoms of reye's syndrome. effects of influenza ... | 1983 | 6615853 |
| on and off sublaminae in the lateral geniculate nucleus of the ferret. | like the retinal ganglion cells from which they receive their input, most relay neurons in the lateral geniculate nucleus have on- or off-center receptive fields with antagonistic surrounds. in the cat, neurons with these two types of receptive fields are anatomically intermingled, even though the on and off systems are functionally segregated. in the ferret, there is a sublamination of the retinal input to lateral geniculate nucleus laminae a and a1. we have investigated the function of this su ... | 1983 | 6619918 |
| sodium and potassium transport in ferret red cells. | potassium movements into ferret red cells were measured with the tracer 86rb. equilibration of 86rb between medium and cells could be resolved into two components. 70-90% occurred rapidly with a rate constant of between 3.5-5.5 h-1. the remaining 10-30% occurred slowly. the slow movement was equivalent to a potassium influx of about 1.2-2.76 mmol l-1 cell h-1. potassium influx was inhibited by 80-90% by 0.1 mm-bumetanide (a high-ceiling, loop diuretic). this suggests that the sodium-potassium co ... | 1983 | 6620190 |
| onset of relaxation in cardiac muscle segments. | the onset of relaxation has been studied in undamaged central segments of isolated ferret papillary muscles at 27 degrees c, 12 beats/min. a technique that provides a signal proportional to the length of a chosen segment was used to assess segment velocity and length. feedback control was employed to obtain segment isometric contractions. at a variety of times during segment isometric twitches, rapid load clamps were imposed using a range of loads from resting force to greater than half peak dev ... | 1983 | 6624929 |
| the role of naturally-acquired bacterial infection in influenza-related death in neonatal ferrets. | concomitant, naturally-acquired bacterial infection was the cause of some deaths occurring in neonatal ferrets infected with the attenuated influenza virus a/puerto rico/8/34, these being prevented by antibiotic therapy. bacterial infection played an insignificant role in the greater number of deaths following inoculation with the virulent clone 7a (of the recombinant influenza virus a/puerto rico/8/34-a/england/939/69/(h3n2]. as seen previously with clone 7a some ferret neonates infected with a ... | 1983 | 6639875 |
| drug effects on afterdischarge and seizure threshold in lissencephalic ferrets: an epilepsy model for drug evaluation. | in normal and lissencephalic ferrets with chronically implanted electrodes, two antiepileptic drugs, (e)-2-[(amino)phenylmethylen]-benzo [b] thiophen-3(2h)-on (af-cx 921 xx) and carbamazepine (cbz), were compared. the variables included afterdischarges (ad) and seizures induced by cortical electrical stimulations (es). both drugs were given orally, 100 mg/kg of pure substance. es was applied before and 1, 2, 3, 4, 5, and 24 h after drug administration. lissencephaly was produced by a single intr ... | 1983 | 6641645 |
| antigenic analysis of h1n1 viruses isolated in the houston metropolitan area during four successive seasons. | we evaluated the antigenic stability of viruses within the h1n1 subtype, using 307 isolates spanning four winter seasons. the isolates from each seasonal period appeared relatively homogenous in hemagglutination inhibition tests employing ferret antisera. however, a panel of seven monoclonal antibodies to a/ussr/90/77 detected extensive micro-heterogeneity. antigenic variation occurred in the hemagglutinin antigen within a few weeks after the initial appearance of a/ussr/90/77-like strains in 19 ... | 1983 | 6642637 |
| sodium/calcium exchange in mammalian ventricular muscle: a study with sodium-sensitive micro-electrodes. | a method for mounting and rapidly perfusing small ventricular trabeculae (diameter around 250 micron) from either ferret or guinea-pig is described. tension, membrane potential (em) and intracellular na activity (aina) were measured. aina was measured using na-sensitive micro-electrodes. at room temperature (22-26 degrees c), [na]o 155 mmol/l and [ca]o 5.4 mmol/l, aina was 10.9 mmol/l +/- s.d. 4.2 mmol/l (n = 148). when [na]o was reduced from 155 to 1.5 mmol/l contractures developed. these were ... | 1983 | 6644617 |
| characterization of an influenza a host range mutant. | a mixed infection of primary chick kidney cells at 38 degrees with a/ann arbor/6/60 cold adapted virus and a/alaska/6/77 wt virus yielded a cold-reassortant virus, cr43-clone 3, which had a host range different from that of either parent. it does not produce detectable virus when grown in madin-darby canine kidney cells, while growing normally in primary chick kidney cells at 33 degrees. both parents, however, grow well in either cell type at 33 degrees c. genotypic analysis of viral rna electro ... | 1983 | 6649412 |
| action of almitrine on the pulmonary vasculature in ferrets and rats. | the action of almitrine on pulmonary vessels was studied under constant ventilation during normoxia and hypoxia. we used ferrets, in which one lobe of lung was perfused with venous blood at constant flow rate in vivo and isolated lungs perfused with blood at constant flow in both ferrets and normal and chronically hypoxic (three weeks in 10% o2) rats. almitrine caused constriction of the relaxed vessels of normoxic lung. during hypoxic pulmonary vasoconstriction, when pulmonary artery pressure ( ... | 1983 | 6652258 |
| [epizootic swine influenza on animal farms in brittany]. | since 1976, seroepidemiological surveys using radial haemolysis and isolation trials from samples collected from pigs at the abattoir showed that brittany was an important reservoir of swine subclinical infections due to the human influenza a viruses h3n2. influenza a h1sw n1sw subclinical infections sporadically occurred from 1979 to 1981. in january 1982 an epizootic started in finistère which spread from west to east. the h1sw and n1sw antigens of 28 stains isolated from 1979 to 1982 were stu ... | 1983 | 6658105 |
| the effects of low sodium solutions on intracellular calcium concentration and tension in ferret ventricular muscle. | papillary muscles from the right ventricles of ferrets were micro-injected with the photoprotein aequorin. both tension and the light emitted by the aequorin, which is a measure of the free intracellular ca concentration [( ca2+]i), were monitored. exposure of the papillary muscle to a solution in which all the na had been replaced by k (0 na(k) solution) resulted in an increase in tension which subsequently slowly decreased. this contracture was associated with a large increase in [ca2+]i follo ... | 1983 | 6663506 |
| vagal influences on the jejunal 'minute rhythm' in the anaesthetized ferret. | spontaneous jejunal motility in the urethane-anaesthetized ferret shows a cyclical pattern of contraction bursts alternating with quiescent periods described as 'minute rhythm' in conscious animals. cooling the cervical vagi to below 4 degrees c or acute vagotomy abolished this pattern of motility. on re-warming the vagi there was a return to cyclical motility after a latency which depended upon the contractile state at the time vagal conduction was restored. electrical vagal stimulation produce ... | 1983 | 6663513 |
| the founding of a cancer registry in a developing country. | the netherlands antilles is among the less developed countries lacking data on incidence and distribution of cancer. therefore, a retrospective case-finding survey was started in 1977 to retrieve all cases of cancer occurring in the period 1968-1977, simultaneously initiating a regular continuous registry for newly occurring cancers. the survey consisted of five phases, designed to ferret out cases from pathology and hospital files, out-patient files, and other sources, and to systematically che ... | 1983 | 6668638 |
| effects of diltiazem on transmembrane potential and current of right ventricular papillary muscle of ferrets. | we studied the effects of diltiazem on electrical properties of isolated ferret right ventricular papillary muscles. by using standard microelectrode recording techniques and current clamp and voltage clamp protocols (single sucrose gap method), we measured action potential variables, depolarization-induced automaticity, slow (or second) inward current (isi) and time-dependent and isochronal (1 sec) outward current. resting potential was unaffected at all concentrations studied (from 2 nm-11 mic ... | 1984 | 6694106 |
| a genetic and monoclonal analysis of high-yielding reassortants of influenza a virus used for human vaccines. | this paper describes two methods of analysis using monoclonal antibodies and rna hybridization to characterize variation in the haemagglutinins of seven high-yielding influenza virus reassortants used for inactivated vaccine production. the results show that variants' were selected in producing these genetic reassortants. the haemagglutinins of two reassortants showed both antigenic and structural differences from their wild-type (wt) parents as detected by the two methods of analysis. these var ... | 1984 | 6699022 |
| muscarinic receptors: evidence for a nonuniform distribution in tracheal smooth muscle and exocrine glands. | muscarinic receptor distribution in smooth muscle, exocrine glands, and epithelium of the ferret trachea was determined using [3h]propylbenzilylcholine mustard ([3h]prbcm) binding and autoradiography. specific, atropine-sensitive [3h]prbcm binding was quantified autoradiographically in the trachealis muscle (approximately 21 binding sites/microns2), surface epithelium (approximately 6 binding sites/microns2), and submucosal glands (approximately 5 binding sites/microns2). serous and mucous cells ... | 1984 | 6699685 |
| dirofilaria immitis infection in three ferrets. | | 1984 | 6706805 |
| an investigation of antigenic drift of neuraminidases of influenza a (h1n1) viruses. | a newly developed lectin neuraminidase test (lnt) and a panel of mouse monoclonal and post-infection ferret antibodies have been used to analyse antigenic drift in n1 neuraminidases of influenza a viruses isolated between 1933 and 1957 and also between 1977 and 1980. significant antigenic differences were detected among the 'early' (1933-57) viruses since the na of viruses isolated one year apart could be distinguished serologically. the na of the 're-emerged' virus a/ussr/92/77 (h1n1) was antig ... | 1984 | 6707471 |
| calcium-dependent mechanical oscillations occur spontaneously in unstimulated mammalian cardiac tissues. | in quiescent rat ventricular myocardium, bathed in solution of 2 mm ca++ or less, it has been previously demonstrated that spontaneous microscopic oscillatory cell motion is present and interacts with an incident laser beam to produce scattered light intensity fluctuations which can be monitored to quantify the underlying motion. the present study shows that scattered light intensity fluctuations are not present under any conditions in frog atrial or ventricular preparations, but do occur in eac ... | 1984 | 6713605 |
| vagal control of colonic motility in the anaesthetized ferret: evidence for a non-cholinergic excitatory innervation. | spontaneous colonic motility in the urethane-anaesthetized ferret consists of two distinct types of contraction which correspond to the patterns recorded myoelectrically in conscious animals. this motility was abolished or greatly reduced when nervous conduction was prevented in the cervical vagi by cooling to below 4 degrees c. on rewarming the nerves the colonic motility returned, after a short latency, to the pre-cool level. atropine transiently abolished colonic motility. on its return the m ... | 1984 | 6716289 |