| effects of the lymphocytosis-promoting factor from bordetella pertussis on the function and potentiality of lymphocytes. i. effect on the ability of lymphocytes to recirculate in the body. | | 1970 | 4317540 |
| enhancement of intracerebral infection of mice with bordetella pertussis. | | 1970 | 4317688 |
| isolation of bordetella pertussis from pernasal swabs stored in stuart's transport medium. | | 1970 | 4317689 |
| intracerebral infection of mice with high-virulence and low-virulence strains of bordetella pertussis. | | 1970 | 4317690 |
| [the fine structure of glycin-induced spheroplasts compared to that of normal bacterial cells of bordetella pertussis]. | | 1968 | 4317773 |
| reduced adjuvant activity of bordetella pertussis vaccine in mice after priming with an immunogenic threshold dose. | | 1970 | 4318029 |
| efficacy of whooping-cough vaccines used in the united kingdom before 1968. a preliminary report to the director of the public health laboratory service by the public health laboratory service whooping-cough committee and working party. | in a large survey of the efficacy of pertussis vaccines made in 33 areas in the united kingdom during the period 1 november 1966 to 31 october 1967 a total of 3,564 households were investigated. nine hundred and seventy-seven strains of bordetella pertussis and 6 strains of bord. parapertussis were isolated from persons in 792 households.after contact in the home 56% of fully vaccinated children under 5 years of age developed a paroxysmal cough, and in more than two-thirds of these patients the ... | 1969 | 4318320 |
| pitfalls in the preparation of monotypic agglutinating antisera for bordetella pertussis. | | 1968 | 4318535 |
| eosinophil leukocyte responses and hypersensitivity reactions in the bordetella pertussis-treated mouse. | | 1970 | 4318636 |
| [immunologically and biologically active cellular components of bordetella pertussis]. | | 1970 | 4318659 |
| the role of surface antigens in the protective potency of bordetella pertussis suspensions as measured by the intracerebral challenge technique in mice. | | 1968 | 4318938 |
| reduced adjuvant activity of bordetella pertussis on the secondary immune response of mice evoked by an immunogenic threshold dose of sheep erythrocytes. | | 1969 | 4319348 |
| antigen-sensitive spleen cells and the adjuvant activity of bordetella pertussis. | | 1970 | 4319471 |
| diagnosis of whooping cough: comparison of serological tests with isolation of bordetella pertussis. a combined scottish study. | antibody titres for bordetella pertussis in paired sera from 223 children with suspected whooping cough showed good correlation by complement fixation and agglutination techniques. the patient's age was related to serological responses and in a different way to b. pertussis isolations: in 73 children under 6 months of age b. pertussis was isolated from nasopharyngeal secretions in 42% and serological findings were positive in 19%; in 11 patients over 1 year of age serological tests were positive ... | 1970 | 4321207 |
| modified state of susceptibility to histamine in mice treated with bordetella pertussis during the neonatal period. | | 1970 | 4321232 |
| the partial purification and some biological activities of histamine sensitizing factor from bordetella pertussis. | | 1970 | 4321640 |
| studies on the leukocytopenia due to acute effects of supernatant fluids of bordetella pertussis cultures. | | 1971 | 4322686 |
| enhancing effect of bordetella pertussis and propranolol on experimental immune hemolytic anemia. | | 1971 | 4323020 |
| lienotoxicity of bordetella pertussis in mice. | | 1971 | 4323399 |
| studies on the leukocytosis and lymphocytosis induced by bordetella pertussis. 3. the distribution of transfused lymphocytes in pertussis-treated and normal mice. | peripheral blood lymphocytes were isolated from normal mice and mice undergoing pertussis-induced lymphocytosis. after labeling in vitro with tritiated uridine the cells were transfused into normal or pertussis-treated mice. it was found that the lymphocytes from pertussis-treated mice entered the lymph nodes of both normal mice and pertussis-treated mice to a significantly lesser extent than did normal lymphocytes which had been transfused into either class of recipient. in addition, an interde ... | 1970 | 4323778 |
| a simple chemically defined medium for the production of phase i bordetella pertussis. | | 1970 | 4324651 |
| the occurrence of bordetella pertussis serotypes in australia, 1950-1970. | | 1971 | 4324689 |
| [characteristics of bordetella pertussis soluble antigens]. | | 1971 | 4325870 |
| experimental acute pulmonary edema in the rat. effect of bordetella pertussis vaccine on ozone mortality. | | 1971 | 4326836 |
| studies on lymphocytes 18. mechanism of lymphocytosis induced by supernatant fluids of bordetella pertussis cultures. | | 1971 | 4326837 |
| [bacteriology of whooping cough. ii. determination of the major agglutinant factors in bordetella pertussis samples isolated in rio de janeiro]. | | 1970 | 4327251 |
| [immunochemical study of the antigenic structure of bordetella genus bacteria. i. immunoelectrophoretic analysis of the antigenic structure of different strains of bordetella pertussis and their biological properties]. | | 1971 | 4328259 |
| [isolation of agglutinogen complex from bordetella pertussis of various serological types]. | | 1971 | 4328260 |
| stimulation of non-specific resistance by heterologous endotoxins and experimental immunity to bordetella pertussis in mice. | | 1971 | 4328408 |
| [epidemiological surveillance of bordetella pertussis and parapertussis sensitivity to antibiotics]. | | 1971 | 4328643 |
| the association of viruses with clinical pertussis. | this study describes the results of attempts to grow viruses from per-nasal swabs taken from 136 children with clinical pertussis.altogether 37 strains of a variety of different viruses were isolated. adenovirus was the most frequent, making up 30% of the total. besides these, herpes simplex, measles, influenza a2, influenza b, mumps, poliovirus and respiratory syncytial virus were detected.bordetella pertussis was isolated from 22% of the cases.it appears that a pertussis-like syndrome can be c ... | 1971 | 4328794 |
| [pathogenesis of experimental allergic encephalomyelitis caused by sensitization with bordetella pertussis combined with cerebral tissue]. | | 1971 | 4329604 |
| disruption of bordetella pertussis in the ribi cell fractionator. 1. effect of different pressures. | | 1971 | 4329814 |
| occasional sporadic cases of whooping cough-like syndrome associated with adenoviral infection: contrast with epidemic whooping cough caused by bordetella pertussis. | | 1971 | 4329891 |
| purified k-agglutinogen of bordetella pertussis and its properties. | | 1971 | 4330023 |
| [antigens of bordetella pertussis and their repercussion in immunization programs against whooping cough]. | | 1971 | 4330706 |
| aggregation of platelets of normal and bordetella pertussis vaccinated mice by atp, adp, and sodium fluoride. | | 1971 | 4331634 |
| [effects of bordetella pertussis injection in newborn mice]. | | 1971 | 4332490 |
| long-term preservation of bordetella pertussis. | viability of bordetella pertussis was preserved when glycerol broth suspensions were quick frozen and stored at -70 c for as long as 45 months. | 1972 | 4333895 |
| international collaborative studies on the pertussis vaccine potency assay. part played by the challenge in the mouse-protection test. | because of wide variations in the methods used to assay the potency of pertussis vaccine, the effect of the type of challenge used in the mouse-protection test was studied. eight laboratories took part in a collaborative investigation and the potencies of 4 pairs of vaccines were estimated. two methods were used, a "local method" using local strains and procedures for challenge, and a "study method" using a distributed strain and a specified procedure. for both methods the challenge level (mouse ... | 1971 | 4334408 |
| detection of bordetella pertussis antibodies in human sera by complement-fixation and immunofluorescence. | the complement-fixation test, as commonly used in the diagnosis of viral infections, was studied for its possible application to the diagnosis of whooping cough and the detection of antibody following pertussis vaccination. the results were compared with those obtained in parallel immunofluorescence tests. cfts were performed on sera from 41 patients with whooping cough (bordetella pertussis isolated), 125 vaccinated persons, and 618 controls; parallel tests by if were made on sera from 24 cases ... | 1972 | 4335341 |
| [influence of bordetella pertussis on the lymphatic tissue of mice. vi. further studies regarding the influence of bordetella pertussis on the immunological memory response]. | | 1971 | 4335600 |
| [immunobiological properties of bordetella pertussis]. | | 1972 | 4336329 |
| an electron-microscope study of intracerebral infection of mice with low-virulence bordetella pertussis. | | 1972 | 4336736 |
| [cell components of bordetella pertussis and their biological activities]. | | 1972 | 4337077 |
| the effect of bordetella pertussis vaccine on protease sensitivity and on the anaphylactic protease production in rats. | | 1972 | 4337080 |
| hemopoietic stem cell proliferation and migration following bordetella pertussis vaccine. | | 1972 | 4337142 |
| time relationships between injection of antigen and adjuvant. ii. immunosuppression induced by bordetella pertussis vaccine when given before secondary antigenic stimulation. | | 1972 | 4337644 |
| autoradiographic studies on cell proliferation during splenomegaly induced by bordetella pertussis in mice. | | 1972 | 4338202 |
| cultural diagnosis of bordetella pertussis infection. | | 1972 | 4338695 |
| the antigen of bordetella pertussis that induces bactericidal antibody and its relationship to protection of mice. | | 1972 | 4338965 |
| studies on the circulation of bordetella pertussis and bordetella parapertussis in populations of children. | | 1972 | 4339092 |
| overcoming of endotoxin--mediated immunosuppression by bordetella pertussis. | | 1972 | 4339277 |
| the reactivity of aged mice to bordetella pertussis as an immunological adjuvant. | | 1971 | 4339715 |
| increased protein synthesis of spleen cells after injection of bordetella pertussis into mice. | | 1972 | 4341374 |
| efficacy of pertussis vaccines: a brighter horizon. | a study of pertussis infections in 186 children under 11 years of age in the manchester region during 1969-71 suggests that recently-manufactured vaccines have been more effective than those made before 1967. the earlier vaccines were effective mainly against the serotypes of bordetella pertussis possessing antigen 2, while those made from 1967 are more nearly equal in their effectiveness against thedi fferent serotypes. a booster dose of the earlier vaccines did not prevent infection with type ... | 1972 | 4341645 |
| the influence of the route of immunization on the protection of mice infected intracerebrally with bordetella pertussis. | the development of immunity in mice to bordetella pertussis induced by intracerebral, intravenous or intraperitoneal vaccination was analysed in terms of the viable bacteria in the brain after intracerebral challenge, the serum antibodies, and protection against the sublethal infection of the lung that follows intranasal inoculation.a vaccine introduced intracerebrally was five to ten times more effective than that given intraperitoneally or intravenously, as measured for each route by the amoun ... | 1972 | 4341998 |
| selective medium for the isolation of bordetella pertussis and parapertussis. | | 1972 | 4342612 |
| effect of lymphocytosis-promoting factor of bordetella pertussis on the immune response. i. suppression of cellular hypersensitivity reactions. | | 1972 | 4342865 |
| effect of lymphocytosis-promoting factor of bordetella pertussis on the immune response. ii. adjuvant effect for the production of reaginic antibody in the rat. | | 1972 | 4342866 |
| specific secondary biological properties of purified rabbit immunoglobulin m and immunoglobulin g antibodies to brucella abortus and bordetella pertussis. | rabbit immunoglobulin (ig)m and igg antibodies to brucella abortus and bordetella pertussis were isolated as purified products and their specific secondary biological activities were compared. igm antibodies were found to be more active than igg proteins in inducing agglutination and sensitization of b. abortus for the complement-dependent bactericidal effect and in inhibiting b. pertussis-induced lymphocytosis in the mouse. igm and igg antibodies were found to be equally effective in inducing a ... | 1971 | 4343404 |
| [influence of bordetella pertussis on the lymphatic tissue of mice. vii. studies on the relationships between the various biological effects induced by bordetella pertussis]. | | 1972 | 4343422 |
| an electron-microscope study of intracerebral infection of mice with low-virulence bordetella pertussis. | | 1972 | 4343581 |
| sensitization of mice by inhalation of antigen after infection with bordetella pertussis. | intranasal infection of mice with bordetella pertussis or injection of pertussis vaccine previous to administration of an albumin aerosol augments sensitivity toward albumin. sensitization was demonstrated by provocation of anaphylactic reactions following intravenous injection of antigen. | 1972 | 4343934 |
| immunization of mice against encephalomyocarditis virus. ii. intraperitoneal and respiratory immunization with ultraviolet-inactivated vaccine: effect of bordetella pertussis extract on the immune response. | mice were immunized by intraperitoneal (ip) or respiratory administration of ultraviolet-inactivated virus alone or with bordetella pertussis extract (bpe) as an adjuvant. the effect of immunization was tested by determination of antibody titers and by survival of a lethal challenge with 200 ld(50) of a virulent (large-plaque variant) strain of emc virus. for plain vaccine the ip 50% effective dose (ed(50)) was 37 hemagglutination units (hau; ca. 4 x 10(6) plaque-forming unit equivalents); with ... | 1972 | 4344027 |
| time relationships between injection of antigen and adjuvant. 3. adjuvancy of bordetella pertussis given at various times after the primary antigenic stimulus. | the adjuvant activity of bordetella pertussis was investigated, both at the cellular and humoral levels, when the bacterial adjuvant was given at various times after the primary antigenic stimulus of both 2 x 10(7) (suboptimal dose) and 4 x 10(8) (optimal dose) of sheep erythrocytes. in all experiments, both adjuvant and sheep erythrocytes were administered by the intraperitoneal route. adjuvant activity was measured on the basis of the early and late phases of the primary response and on the de ... | 1972 | 4344394 |
| leucocytosis-promoting factor of bordetella pertussis. i. purification and characterization. | the leucocytosis-promoting factor was purified from the supernatant fluid of spent cultures of bordetella pertussis on solid medium. after precipitation at 67% saturation of ammonium sulfate, the leucocytosis-promoting factor was extracted with a 1.0 m nacl solution. purification was accomplished by starch block electrophoresis and sucrose density gradient centrifugation. the purified preparation contained a high leucocytosis-promoting activity, and as small an amount as 0.04 mug of protein indu ... | 1972 | 4344632 |
| distribution of labeled lymph node cells in mice during the lymphocytosis induced by bordetella pertussis. | the mechanism by which bordetella pertussis organisms and their products induce lymphocytosis in mice was analyzed in terms of the localization of syngeneic cr-51-labeled lymph node cells. labeled lymphoid cells incubated in vitro with the supernatant of b. pertussis cultures and then injected intravenously into normal recipients, or labeled cells injected into pertussis-treated recipients were unable to "home" to lymphoid organs but persisted for long periods in the blood. in animals "equipped" ... | 1972 | 4345107 |
| the pathology and immunology of bordetella pertussis infection. | | 1972 | 4345765 |
| an electron-microscopic study of intracerebral infection of mice with low-virulence bordetella pertussis. | | 1972 | 4345768 |
| passive protection of mice against intracerebral infections with bordetella pertussis. | the passive protection of mice against an intracerebral infection with bordetella pertussis, by antiserum introduced directly into the brain with the infecting organisms, was compared with the protection afforded by intraperitoneal antiserum. the antibody effective by the intracerebral route is that which is adsorbed onto the infecting organisms, although it does not affect the viability of the organisms in vitro in the absence of complement.passive protection against organisms introduced intrac ... | 1972 | 4346011 |
| areexamination of phase iv bordetella pertussis. | | 1972 | 4346447 |
| efficacy of whooping-cough vaccines used in the united kingdom before 1968. | the efficacy of pertussis vaccines was investigated in 33 areas in the united kingdom from november 1966 until april 1968 inclusive. bordetella pertussis was isolated from 1,293 persons, but there were only six isolations of b. papapertussis. among vaccinated contacts under 5 years in homes in which b. pertussis was isolated 52% developed paroxysmal cough. the corresponding attack rate among unvaccinated contacts was 69%. these findings suggest that much of the pertussis vaccine in use for five ... | 1973 | 4346578 |
| the effect of bordetella pertussis on lymphocyte cyclic amp metabolism. | bordetella pertussis culture fractions produce decreased metabolic responses to isoproterenol and epinephrine in mice and rats, suggesting the possibility of systemic beta adrenergic blockade. the present study was undertaken to elucidate the mechanism of the alteration in adrenergic responsiveness and to clarify its relationship to other biological effects of the organism. lymphocytes were selected as a suitable tissue because of the marked alteration in lymphocyte distribution in pertussis-tre ... | 1973 | 4348277 |
| pertussis antibodies in the sera of children exposed to bordetella pertussis by vaccination or infection. | low agglutinin titres to pertussis suspensions were found in 99% of sera from a group comprising healthy adults and non-vaccinated, non-infected infants of 1-6 months of age. these are attributable to agglutinins to heat-stable antigens and/or heat labile agglutinogen 1, and cross-absorption tests must be done on the sera in order to distinguish between the two. agglutinins to agglutinogens 2 and 3 were found in only about 20% of adult sera. bactericidal antibody was low in titre or absent in al ... | 1973 | 4348456 |
| induction of specific unresponsiveness with the aid of bordetella pertussis. | | 1973 | 4348708 |
| [histamine-sensitizing action of bordetella pertussis strains isolated from patients]. | | 1973 | 4350721 |
| the free lipids of brucella melitensis and bordetella pertussis. | | 1973 | 4351160 |
| adjuvants for a tumor-specific vaccine: bordetella pertussis or mycobacterial cell walls attached to oil droplets. | | 1973 | 4351399 |
| interaction of lymphoid and nonlymphoid cells with the lymphocytosis-promoting factor of bordetella pertussis. | the activity of soluble lymphocytosis-promoting factor (lpf) from bordetella pertussis decreased after brief in vitro incubation with lymphoid cells or erythrocytes. the lpf activity was found to be associated with the cells used, and injection of the cells produced a leukocytosis and lymphocytosis which completely accounted for the loss of soluble activity. attachment of lpf to cells was found to be reversible in vitro. it is suggested that reversible binding occurs in vivo. | 1973 | 4351588 |
| leukocytosis-promoting factor of bordetella pertussis. ii. biological properties. | the leukocytosis-promoting factor (lpf), purified from materials extracted from agar in which bordetella pertussis was grown, caused leukocytosis and an increased sensitivity to histamine when as little as 0.04 mug of protein was given intravenously to mice. lpf was adsorbed onto erythrocytes, causing hemagglutination. as little as 0.03 mug of lpf protein agglutinated chicken erythrocytes in 0.05 ml of a 0.5% suspension. the physicochemical, biological, and immunological properties indicated tha ... | 1973 | 4351972 |
| immunoglobulin and histamine-sensitivity response of mice to live bordetella pertussis. | mice injected intranasally (it.n.) and intraperitoneally (i.p.) with a nonlethal dose (2.5 x 10(5) colony-forming units) of live bordetella pertussis were examined for 50 days for infection, respiratory tract immunoglobulins (ig), changes in serum ig, and histamine sensitivity. with mice infected it.n., respiratory infection markedly declined between day 20 and day 30. ig classes (a, g(1), g(2a), g(2b), but no m), which had specificity for b. pertussis, were present in tracheobronchial wash (tbw ... | 1973 | 4352456 |
| interferon production by bordetella pertussis components in rabbits and in rabbit cell cultures. | | 1973 | 4353287 |
| effect of bordetella pertussis vaccine on plasma corticosterone level and on acth-induced corticosterone secretion in rats. | | 1973 | 4354053 |
| bordetella pertussis infection in chandigarh. | | 1973 | 4357930 |
| [influence of bordetella pertussis on the lymphatic tissue of mice. 8. the influence of bordetella pertussis on the primary and secondary immune potential of thymusless ("nude") mice (author's transl)]. | | 1973 | 4358740 |
| recovery of the antibody-forming potential in cyclophosphamide-treated mice, with special reference to the influence of bordetella pertussis. | | 1974 | 4358749 |
| lymphocytosis induced in mice by supernatant fluids of bordetella pertussis cultures: a histopathological study. | | 1973 | 4360363 |
| experimental pertussis infection in the marmoset: type specificity of active immunity. | although we have failed to produce either paroxysmal cough or vomiting in rhesus monkeys, cynomolgus monkeys and marmosets, we have found in marmosets several features of pertussis infection similar to those seen in children with whooping cough: catarrh, persistence of colonization of the naso-pharynx with bordetella pertussis for 4-11 weeks, change of serotype during colonization and inability of type 1 organisms to establish themselves as the predominant serotype.as in children, we have found ... | 1974 | 4362410 |
| the delayed and lasting rejection of mammary adenocarcinoma cell tumors in dba-2 mice with use of killed bordetella pertussis. | | 1974 | 4363061 |
| suppression of sv40 tumors after immunization with group a streptococcus pyogenes and bordetella pertussis. | | 1974 | 4363064 |
| leukocytosis-promoting factor of bordetella pertussis. 3. its identity with protective antigen. | leukocytosis-promoting factor (lpf) was purified from the supernatant of a 5-day liquid culture of bordetella pertussis strains tohama and no. 134. the preparations appeared to be filamentous molecules (2 by 40 nm) and contained histamine-sensitizing and hemagglutinin activities in addition to leukocytosis-promoting activity. active protection tests in mice demonstrated strong protective activities of 80 international protective units per mg of protein in lpf preparations of each strain toxoided ... | 1974 | 4363229 |
| bordetella pertussis serotypes in a whooping cough outbreak. | | 1974 | 4363474 |
| specific unresponsiveness to skin allografts in mice. 3. synergistic effect of tissue extracts, bordetella pertussis, and antilymphocytic serum. | | 1974 | 4363833 |
| [determination of the serotypes of strains of bordetella pertussis isolated between 1952 and 1971 in rumania]. | | 1974 | 4363932 |
| [characteristics of the serological properties of bordetella pertussis variants with defective cell walls]. | | 1974 | 4364446 |
| epstein-barr virus-associated membrane-reactive antibodies during long term survival burkitt's lymphoma. | antibodies to epstein-barr virus associated cell membrane antigens persisted or slowly decreased during prolonged uncomplicated survival of patients with burkitt's lymphoma in remission. serum was sampled from four patients within 6 months before recurrence occurring after the first year and preceded by remission during more than 6 months. rapid and significant decreases of the antibodies before clinical recognition of the recurrences were found in three patients. the fourth patient had slowly i ... | 1974 | 4364538 |
| proceedings: active enhancement of mouse skin allografts: the effect of bordetella pertussis and regional lymphadenectomy. | | 1974 | 4364996 |
| sensitization to ragweed pollen in bordetella pertussis-infected or vaccine-injected mice. | | 1974 | 4365297 |
| [symposium i: structure and function of cilia of bordetella pertussis]. | | 1974 | 4365639 |