| complement lysis of resealed red cell membrane ghosts pretreated with glutaraldehyde. | | 1979 | 109512 |
| in vitro stimulation of natural killer (nk) cells by soluble factor(s) generated in antigen-stimulated rhesus monkey peripheral blood lymphocyte cultures. | peripheral blood lymphocytes from rhesus monkeys (macaca mulatta) sensitized to keyhole limpet hemocyanin (klh), when stimulated in vitro with klh, developed natural killer (nk) cell activity that was assayed with rous sarcoma virus-transformed marmoset fibroblasts as targets in a 4-hr 51cr-release assay. the supernatant fluids from 24- to 25-hr klh-activated cultures were capable of stimulating nk development in nonsensitive lymphocyte cultures. the effector cells were neither macrophages nor b ... | 1979 | 109523 |
| c1q: isolation from human serum in high yield by affinity chromatography and development of a highly sensitive hemolytic assay. | c1q, a subcomponent of the first component of complement, has been isolated from human serum in fully hemolytically active form by affinity column chromatography and gel filtration with bio-gel a-5m. the affinity column was prepared by covalent coupling of purified human igg to cnbr-activated sepharose 4b. final yields of c1q ranged from 25 to 40% with 650- 890-fold purification based on recovery of hemolytic activity. the preparations were free of contaminating serum proteins as judged by sds-p ... | 1979 | 109524 |
| hanganutziu-deicher antigen and antibody in pathologic sera and tissues. | heterophile, hanganutziu-deicher (h-d) antigen was studied in pathologic sera by means of inhibition of agglutination of bovine erythrocytes by h-d antibodies. h-d antigen was demonstrated in 38% of random cancer sera, 25% of lymphoma or leukemia sera, 25% of leprosy sera, 8% of infectious mononucleosis sera, 6% of rheumatoid arthritis sera, and 27% of synovial fluids of rheumatoid arthritis patients. none of 134 normal human sera gave positive results. some of the inhibition-positive cancer ser ... | 1979 | 109527 |
| studies on the terminal stages of immune hemolysis. v. evidence that not all complement-produced transmembrane channels are equal. | the inhibitory effects of 0.1 m edta on the lysis of e prepared by incubating ea with whole gpc was studied. at high end point lysis (greater than 70%) 0.1 m edta failed to prevent hemoglobin release whereas at lower end point (less than 60%) 0.1 m edta was effective. in all cases hemoglobin release was inhibited by 25% bsa. when e were prepared by incubating eac1-8 with c9, similar results were obtained. in this system the difference in the ability of 0.1 m edta to inhibit hemoglobin release at ... | 1979 | 109540 |
| studies on the terminal stages of immune hemolysis. vi. osmotic blockers of differing stokes' radii detect complement-induced transmembrane channels of differing size. | we have previously shown that 0.1 m edta could be used to distinguish functionally different transmembrane channels produced during complement-(c) mediated hemolysis of e. in this paper we have studied the ability of sugars of varying stokes' radii to prevent hemoglobin release from e intermediates whose lysis was inhibitable or not inhibitable by edta. on the basis of these experiments we propose that the inhibition of e transformation by high molarity edta occurs by virtue of the size of the e ... | 1979 | 109541 |
| complement fixation by rh blood group antibodies. | rh blood group antibodies normally do not fix complement. rh positive intact red blood cells treated with papain do not lyse when incubated with corresponding antibody and complement. this study was done to determine if complement fixation occurs when antibodies were combined with rh positive red blood cell ghosts untreated or treated with papain. complement fixation was observed with igg anti-d, anti-dc and anti-c when papain treated ghosts were used. no complement fixation or a smaller degree ... | 1979 | 109952 |
| tricuspid atresia in a foal and a lamb. | | 1979 | 110011 |
| elevated concentrations in serum immunoglobulins due to infection by ovine progressive pneumonia virus. | sixty-seven serum samples were obtained from 2 sheep flocks. agar gel immunodiffusion (agid) was used to separate progressive pneumonia virus (ppv)-infected sheep from noninfected sheep by the presence of precipitating antibodies. immunoglobulin (ig), total protein, and albumin concentrations were then measured from all 67 sera to determine whether differences existed between ppv-infected and non-infected sheep. a significant difference (p less than 0.0005) was found in both total protein and ig ... | 1979 | 110182 |
| selective accumulation and depletion of polychlorinated biphenyl components: food animal implications. | | 1979 | 110193 |
| protein fractionation, nucleic acids, and enzymatic activity of cytoplasmic extracts from the intestinal mucosa of sheep. | | 1979 | 110321 |
| c3 activation by monosodium urate monohydrate and other crystalline material. | monosodium urate monohydrate (msum) is a potent activator of the complement system as measured by electrophoretic conversion of beta1c to beta1a. activation of c3 in human serum by msum is both time- and dose-dependent. the sensitivity of the assay allows detection of c3 activation by as little as 0.2 mg/ml of msum. it was observed that c3 activation is calcium dependent and elimination by both edta and egta, a finding that demonstrated the major role of the classic pathway of complement activat ... | 1979 | 110337 |
| circulating levels of chorionic gonadotropin and progesterone in the rhesus monkey treated with lh antiserum during early gestation. | | 1979 | 110373 |
| [demonstration and evolution of chorionic gonadotropin in ewes]. | occurrence of ovine chorionic gonadotropin (ocg) is demonstrated in placenta and amniotic fluid with the use of a radioreceptor assay (corpus luteum membranes) in ewes. identification of ocg is possible as early as 15th day of pregnancy. it should be secreted at a constant rate, and its maximum concentration is recorded on the 130th day. this hormonal factor might be one of the major components accountable for high progesteronemia observed during the 100 last days of pregnancy. | 1979 | 110484 |
| epididymitis in rams: effect of vaccination and culling on the clinical incidence of the disease. | ram epidiymitis caused by brucella ovis can be effective controlled by an annual program combining rigorous culling clinically affected animals and appropriate vaccination of the remaining animals. yearling rams purchased or saved as replacement breeders should be immunized at 4-5 months of age by two injections of br. ovis bacterin spaced 3-6 weeks apart. annually, approximately one month prior to the breeding season, all rams, replacements and older breeders as well, should be carefully examin ... | 1979 | 110514 |
| epididymitis in rams: studies on vaccine efficacy. | simultaneous inoculation with br. ovis bacterin plus br. abortus strain 19 produced the greatest immunity. this procedure was not permitted, however, as widespread use of br. abortus in sheep might pose a hazard to the brucellosis eradication program in cattle. subsequent work demonstrated that an aluminum hydroxide adsorbed bacterin, administered as two injections spaced 3-6 weeks apart, conferred a significant and acceptable level of immunity. | 1979 | 110515 |
| production of exotoxin a by pseudomonas aeruginosa in a chemically defined medium. | a defined medium was developed in which easily measured quantities of exotoxin a (pe) were produced by pseudomonas aeruginosa pa-103. the medium contained three l-amino acids (arginine, aspartic acid, and alanine), basal and trace salts including 14 mm k2hpo4, 14 mm glucose, and 140 mm glycerol. the concentrations of amino acids which yielded most satisfactory results were 6 mm alanine, 13 mm aspartic acid, and 16 mm arginine. the identity of pe in the culture supernatant fluid was demonstrated ... | 1979 | 110687 |
| isoproterenol and aminophylline reduce lung capillary filtration during high permeability. | pseudomonas bacteremia in sheep causes a prolonged increase in lung vascular permeability to protein. isoproterenol and aminophylline could effect lung fluid balance after pseudomonas by reducing vascular pressures or by blocking release of permeability mediators. we measured vascular pressures, lung lymph flow, and lymph and plasma protein concentrations in unanesthetized sheep under baseline conditions and during steady-state increased permeability after pseudomonas. pseudomonas caused pulmona ... | 1979 | 110756 |
| a simple microassay for detection of antibodies to fetal calf serum and related antigens and its application to the serological definition of human tumor antigens. | | 1979 | 110885 |
| immunoregulation in infection caused by mycobacterium tuberculosis: the presence of suppressor monocytes and the alteration of subpopulations of t lymphocytes. | this study was designed to characterize qualitative and quantitative alterations, occurring before and during chemotherapy, in the mononuclear cells of patients with infections caused by mycobacterium tuberculosis. a hemolytic plaque-forming (pfc) assay indicated that the production of antibody to sheep red blood cells by pokeweed mitogen (pwm)-stimulated lymphocytes was suppressed in treated and untreated patients as compared with that in normal adult donors (p less than 0.001). the removal of ... | 1979 | 110887 |
| immunosuppression by a mouse tumor resembles antigenic competition. | the intraperitoneal injection of gamma-radiated, uv-radiated, or unradiated p-815 tumor cells into syngeneic or allogeneic mice suppressed the immune response to a subsequent intraperitoneal injection of sheep erythrocytes in a manner similar to the suppression caused by the injection of manner similar to the suppression caused by the injection of horse erythrocytes and termed antigenic competition. in both cases, the greatest suppression occurred when the sheep erythrocytes were injected at the ... | 1979 | 111246 |
| [toxoplasmosis of sheep in the lowland region of western slovakia]. | the author describes the serological demonstration of toxoplasma antibodies in sheep of ten flocks kept in the lowland region of western slovakia. the results of serological examination by the complement-fixation reaction (cfr) were positive in different degrees in nine flocks. in the remaining flock the blood of the sheep was not found to contain such antibodies. at the locality l. the author selected a small group of serologically positive sheep from the group of animals to be slaughtered and ... | 1979 | 111394 |
| [serum selenium levels in sheep from birth to 90 days of age]. | the results of the study of the dynamics of selenium in the blood serum were compared in 31 piglets from birth to the age of 90 days. the analyzed selenium values in the blood serum immediately after birth (0.14--0.20 ppm) provide evidence of the intra-uterine placental passage of selenium. in the period of colostral and milk nutrition, the serum concentrations of selenium showed a statistically insignificant variation, followed by an abrupt drop of the level of the microelement in the weaning p ... | 1979 | 111398 |
| prostaglandin f2 alpha and its 13-dehydro analogs: comparative luteolytic effects in vivo. | prostaglandin f2 alpha (pgf2 alpha) was identified as a luteolytic hormone in sheep (nature, new biol. 238, 129, 1972). attempts to use pgf2 alpha for the pharmacological control of luteolysis in normal cycling sheep met with only partial success due to the rapid clearance of pgf2 alpha from the blood. in addition treated animals showed moderate to severe cardiovascular and gastrointestinal side effects. accordingly, experiments were carried out to determine whether pg analogs might be more effe ... | 1979 | 111476 |
| peroxidatic oxidation of benzo[a]pyrene and prostaglandin biosynthesis. | the arachidonic acid dependent oxidation of benzo[a]pyrene to a mixture of 3,6-, 1,6-, and 6,12-quinones has been studied by using enzyme preparations from sheep seminal vesicles. maximal oxidation is observed at 100 microm benzo[a]pyrene and 150 microm arachidonic acid. the arachidonic acid dependent oxidation is peroxidatic and utilizes prostaglandin g2 (pgg2), generated in situ from arachidonate, as the hydroperoxide substrate. 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid is equivalent to p ... | 1979 | 111706 |
| anti-keratin antibodies in rheumatoid arthritis. | a naturally occurring antibody that reacts with the keratinised tissue of animal oesophagus was found in the serum of 75 out of 129 patients (58%) with classical or definite rheumatoid arthritis (ra) but not in sera from 105 healthy people. detection of the antibody, which is unrelated to rheumatoid factor, is more specific for ra than the reaction in the sheep-cell agglutination test but less sensitive. | 1979 | 111762 |
| [abnormal animal behavior]. | | 1979 | 111800 |
| [immunological characterization of human chronic lymphatic leukaemia (author's transl)]. | | 1979 | 112007 |
| mechanisms of clonal abortion tolerogenesis. ii. clonal behaviour of immature b cells following exposure to anti-mu chain antibody. | this paper uses b-lymphocyte cloning methods to quantify the effects of anti-mu chain antibody on immature and mature b cells. nude mouse spleen lymphocytes were incubated with various concentrations of sheep anti-mouse mu chain antibody for times varying from 10 min to 24 h. they were then washed and plated in the agar b-cell colony formation assay. five to six days later, control b cells had developed into colonies with a plating efficiency of about 5%. b cells from newborn mice pretreated wit ... | 1979 | 112040 |
| receptors for activated c3 on thymus-dependent (t) lymphocytes of normal guinea-pigs. | in a survey of lymphocyte subpopulations in normal guinea-pig blood, lymph node, spleen, thymus and peritoneal cavity, a considerable overlap was observed between the percentages of c3-receptor bearing lymphocytes (crl) and of thymus-dependent (t) cells in lymph nodes. simultaneous rosette-formation reactions with sheep erythrocytes carrying rabbit complement (eac) and papain-treated rabbit erythrocytes (a t-cell marker) revealed that 20--50% of the lymph node crl were t lymphocytes. these exper ... | 1979 | 112046 |
| a comparative study of serum phospholipase a2 in man & animals--some biochemical & physiological implications. | | 1979 | 112047 |
| nephelometric activity as a criterion of adequate antisera for use in immunofluorescence. | we have characterized monospecific sheep antisera to human igg, iga and igm using ouchterlony double diffusion, immunoelectrophoresis, quantitative precipitation and nephelometric activity. the antisera were conjugated at high and low f/p ratios, absorbed and subsequently evaluated in both direct and indirect immunofluorescence. antisera which exhibited excellent reactivity in double diffusion, iep and quantitative precipitation but gave a poor nephelometric response (ab dilution greater than 1/ ... | 1979 | 112064 |
| lymphocytes with immunoglobulin e fc receptors in patients with atopic disorders. | lymphocytes from normal nonallergic donors and patients with atopic disorders were analyzed for subpopulations bearing fc receptors for immunoglobulin (ig)e (fc(epsilon)) and igg (fc(gamma)), surface igm (sigm) and igd (sigd), and for t cells forming spontaneous rosettes with sheep erythrocytes (e). the patients were divided into three groups according to serum ige concentrations and systemic corticosteroid treatment. group i consisted of 12 atopic patients with either normal or moderately incre ... | 1979 | 112109 |
| [epidemiologic and serologic study of listeriosis in man and domestic and wild animals in austria]. | in the framework of a study aimed to ascertain the possibilities of infection transmission from mother to child the athors examined serologically gravid women for toxoplasmosis and antibodies against listeriosis, using routine methods, in austria in 1974, 1975 and 1975. almost all gynecologists of the region of styria (austrial), who systematically delivered data concerning abortions, premature births and stillbirths, were invited to take part in the study. at the same time data concerning domes ... | 1978 | 112179 |
| [immune response genes]. | | 1978 | 112659 |
| [the influence of endogenous insulin and glucagon on the free fatty acids in the circulating blood plasma]. | the effect of increased endogenous plasma insulin and glucagon concentrations on the free fatty acid (ffa) levels in the circulating blood was investigated in sheep, 2 baboons and 1 vervet monkey. elevation of the plasma insulin level was obtained by vagal stimulation or intravenous glucose administration and vagal stimulation, whereas increased glucagon levels were induced by sympathetic stimulation, increased plasma insulin levels, with simultaneous increased plasma glucose concentrations (in ... | 1979 | 112697 |
| a study of leptospirosis among animals in barbados w.i. | microscopic agglutination tests performed during 1971 and 1972 on barbadian livestock showed positive serological reactions for leptospirosis as follows: cattle 51%, pigs 13%, sheep 18%, horses 64% and goats 19%. the serogroup autumnalis predominated in all but horses in which the reactions to the pyrogenes group appeared slightly higher. after the isolation of a strain of leptospira serotype fort-bragg (barbadian strain no. 119) of the autumnalis serogroup in 1973, and its subsequent inclusion ... | 1979 | 112729 |
| the reliability of the immunodiffusion-precipitation test in enzootic bovine leucosis. | | 1977 | 112843 |
| purification by affinity chromatography and some properties of microsomal galactosyltransferase from pig thyroid. | membrane-bound 4-beta-galactosyltransferase (lactose synthase; udp galactose: d-glucose 4-beta-galactosyltransferase, ec 2.4.1.22) was purified 1500-fold to near homogeneity from pig thyroid microsomes with about 30% yield. the purified enzyme behaved as a lipophilic protein, rapidly losing activity and aggregating if not supplemented with either triton x-100 or serum albumin (both of these were equally effective for long-term stabilization). the enzyme preparation showed an absolute requirement ... | 1979 | 113033 |
| the evaluation of selected parameters of immune function in asthmatics after long-term corticosteroid therapy. | the availability of inhaled beclomethasone diproprionate permitted the discontinuation of continuous, long-term systemic corticosteroid therapy (sct) in a group of asthmatics who had previously required sct to control their asthma. twelve patients had been on sct for a period of 2-22 years with an average duration of 7 years. to determine whether this previous long-term sct and the current use of inhaled beclomethasone diproprionate had an effect on leucocyte functions, a variety of studies refl ... | 1979 | 113132 |
| distribution of endogenous cobalamin between the transcobalamins in various mammals. | 1. plasma samples from ten mammals were chromatographed on sephadex g-200 columns and the total cobalamin content of each fraction was determined. 2. unlike the situation in man, the bulk of the endogenous plasma cobalamin was found attached to a transcobalamin ii-like protein in all ten animals. transcobalamin 0 carried between 3 and 20% and this proportion appeared to be inversely related to the plasma total cobalamin. no endogenous cobalamin peak corresponding to transcobalamin i was detected ... | 1979 | 113164 |
| element and polychlorinated biphenyl deposition and effects in sheep fed cabbage grown on municipal sewage sludge. | sheep were fed a diet containing 30 per cent (dry weight) cabbage which had been grown on municipal sewage sludge from syracuse, ny for 77 days. slight increases were found in the concnetration of nickel in kidney, copper in liver and cadmium in certain animal organs as compared to those in sheep fed a control ration containing cabbage grown on soil. polychlorinated biphenyls were also found at higher levels in the sludge-grown cabbage and in the livers of the respectively fed sheep as compared ... | 1979 | 113171 |
| [epidemiology and diagnosis of listeria infections. 1]. | | 1979 | 113195 |
| potency testing of anthrax spore vaccine (living) in guinea pigs. | | 1979 | 113339 |
| conformation-specific antibodies to the alpha chain cooh terminus of hemoglobin a0. | an anti-hemoglobin antiserum obtained from a sheep immunized with human carboxyhemoglobin a0 demonstrated little difference in its reactivity with deoxy- or carboxyhemoglobin a0. however, a subpopulation of this antiserum isolated by synthetic peptide affinity chromatography clearly distinguished between these two hemoglobin species. this subpopulation, designated alpha(129-141) anti-hemoglobin antibodies, represents less than 1% of the total anti-hemoglobin antibodies. they are nonprecipitating ... | 1979 | 113408 |
| rickettsial hemolysis: rapid method for enumeration of metabolically active typhus rickettsiae. | a new assay is described for enumerating biologically active typhus rickettsiae (madrid e strain), based on adsorption of rickettsiae to erythrocytes in the presence of naf (which allows adsorption but not lysis) and lysis in the presence of anti-rickettsia prowazeki immune serum (which allows only a single round of lysis). the number of lysed erythrocytes is then used to estimate the number of active rickettsiae. | 1979 | 113426 |
| measurement of antibodies to tubulin by radioimmunoassay. | a solid-phase double antibody radioimmunoassay capable of measuring antibody to tubulin, the principal component of microtubules, is described. this assay is simple, combining sensitivity with specificity and also allowing determination of antibody subclasses. | 1979 | 113464 |
| the discovery of a particle unique to brain and spleen subcellular fractions from scrapie-infected mice. | | 1979 | 113498 |
| phagocytosis and trypsin-resistant glass adhesion by osteoclasts in culture. | osteoclasts were cultured in vitro and tested for the functions normally associated with cells of the mononuclear phagocyte system. they were found to ingest glutaraldehyde-fixed red cells and latex, but not opsonised or complement-coated sheep red cells. osteoclasts are glass-adherent and resist removal by trypsin. the implications of these findings for the identity of the osteoclast precursor cell and its mechanism of fusion are discussed. | 1979 | 113514 |
| [cranio-mandibular morphogenesis. the base of the skull and the pterygoid process]. | | 1978 | 113718 |
| [involvement of mycoplasma ovipneumoniae in enzootic proliferating interstitial pneumonia in sheep]. | | 1979 | 113871 |
| splenectomy in sheep. technique, haematological changes, and the haematology of the precipitated anaplasmosis and babesiosis. | | 1979 | 113963 |
| comparison of agar gel precipitation and complement fixation test for the detection of brucella ovis infection. | blood samples from 710 sheep raised in 20 different farms were examined for brucella ovis antibodies. thirty samples were positive with complement fixation, 35 samples with precipitation, and 58 samples with both tests. it has been concluded that the gel precipitation technique is adequate for screening but for individual testing both methods should be used simultaneously. | 1979 | 113989 |
| listeriosis in sheep. listeria monocytogenes excretion and immunological state in healthy sheep. | | 1979 | 114002 |
| isolation and characterization of an active variable domain from a homogeneous rabbit antibody light chain. | the variable domain (vl) of allotype b4 light chains of rabbit igg was isolated from both nonimmune heterogeneous igg and a homogeneous antibody directed against type iii pneumococcal polysaccharide. light chains were first isolated and then cleaved under mild acidic conditions between residues 109 and 110. reduction with dithiothreitol in guanidine hydrochloride cleaved both intradomain disulfide bridges as well as the interdomain disulfide bridge joining the variable and constant domain. the s ... | 1979 | 114216 |
| induced hypocalcaemia in cows and sheep. i. changes in plasma inorganic phosphorus levels. | | 1979 | 114267 |
| immunogenicity and kinetics of distribution and elimination of sheep digoxin-specific igg and fab fragments in the rabbit and baboon. | to evaluate the relative merits of purified igg and fab preparations of defined specificity for potential clinical use, immunogenicity studies were carried out in baboon and rabbit experimental models. distribution and elimination kinetics of purified sheep digoxin-specific igg and fab fragments were also studied following intravenous administration to baboons. serial plasma and urine fab concentrations were determined from trichloroacetic acid-precipitable 125i counts from pre-labelled preparat ... | 1979 | 114346 |
| growth enhancement and serum replacement in cloning of murine mastocytoma and granulocyte/macrophage precursor cells: two distinct activities present in hemolysates. | in the present study we investigated the serum replacing and enhancing activities of erythrocyte lysates, obtained from different animal species, on the growth of murine mastocytoma cells and normal granulocyte/macrophage precursor cells (cfu-c) present in bone marrow. the soft agar technique for cloning hemopoietic cells in vitro was used to quantitate the growth of these cells in culture. rat, rabbit, guinea pig, mouse and sheep hemolysates were tested for their capacity to replace or to enhan ... | 1979 | 114402 |
| differences of chemical structures of pseudomonas aeruginosa lipopolysaccharide essential for adjuvanticity and antitumor and interferon-inducing activities. | | 1979 | 114416 |
| a novel carbonic anhydrase from the ovine parotid gland. | | 1979 | 114424 |
| visual thalamocortical connections in sheep studied by means of the retrograde transport of horseradish-peroxidase. | in order to study the visual thalamocortical connections in the sheep, horseradish peroxidase (0.3--0.5 microliter of a 30% solution) has been injected in the gyri marginalis, ectomarginalis medius pars medialis, ectomarginalis medius pars lateralis and ectosylvius caudalis. the results show that: (1) the dorsal lateral geniculate nucleus (lgnd) projects to the former three gyri. dorsal parts of the lgnd project to caudal areas, whereas its ventral parts project to rostral areas of these gyri; m ... | 1979 | 114554 |
| studies on the fc gamma receptor of the murine macrophage-like cell line p388d1. i. the binding of homologous and heterologous immunoglobulin g1. | | 1979 | 114580 |
| on the interaction of rabbit c1q with sheep and rabbit immune complexes. | | 1979 | 114586 |
| the quantitation of alternative pathway complement function by timed lysis assay. | a simple timed lysis assay is described for quantifying haemolytic complement activity in human serum. classical pathway complement function was determined by measuring the time taken to lyse 50% of a standard suspension of antibody-coated sheep erythrocytes; the time required for 50% lysis of a standard rabbit erythrocyte suspension was similarly used to evaluate alternative pathway function. because target erythrocytes prepared on different days gave slightly different 50% lysis times, it was ... | 1979 | 114593 |
| immunopharmacology of auranofin and gold sodium thiomalate: effects on humoral immunity. | the effect of auranofin and gold sodium thiomalate (gst) on antibody production was evaluted using antibody-dependent cellular cytotoxicity and complement-dependent antibody responses to sheep red blood cells (srbc) and l929 fibroblasts. the results indicated that auranofin was capable of depressing antibody production to l929 cells, but inconsistently depressed the response to srbc in the mouse. gst, however, stimulated both responses. in vitro, both compounds inhibit secretion of antibody. the ... | 1979 | 114651 |
| abnormalities in clonable b lymphocytes and myeloid progenitors in autoimmune nzb mice. | cloning procedures were used to study b lymphocytes and progenitors of granulocytes and macrophages in nzb mice. numbers of b cells that were detected in sheep erythrocyte-containing semisolid cultures were only slightly elevated in nzb tissues, and these were normally sensitive to inhibition by anti-mu or anti-delta antibodies or prostaglandin e. however, nzb mice rapidly developed large numbers of b cells that could be cloned in the presence of lipopolysaccharide, and these included unusual an ... | 1979 | 115001 |
| endocrine control of parturition. | | 1979 | 115023 |
| energy metabolism in the developing brain. | | 1979 | 115093 |
| fatty acid metabolism during development. | | 1979 | 115094 |
| augmentation of the glucose supply in the fetus and newborn. | | 1979 | 115095 |
| fetal-placental nitrogen metabolism. | | 1979 | 115096 |
| transplantation of the testis. | | 1979 | 115123 |
| the effect of thyrotrophin releasing hormone on pituitary and thyroid function in pre- and post-natal lambs. | | 1979 | 115196 |
| [anesthsiological experiences in experimental surgery]. | the paper reports experience with methods of anaesthesia in rabbits, rats, mice, guinea-pigs, pigs, sheep, baboons, dogs and cats. special problems of handling, mode of injection and intubation are discussed. a comprehensive survey of literature provides further information about the proposed patterns of anaesthesia and informs about other anaesthetic methods, not practised by the authors. | 1979 | 115325 |
| effect of heat stress on plasma concentrations of prolactin and luteinizing hormone in ewes. | basal concentrations of prolactin but not luteinizing hormone were elevated in ewes by 8--10 h of heat stress given daily during the first 11 days of their oestrous cycle. however, the prolactin and luteinizing hormone responses to thyrotrophin releasing hormone and gonadotrophin releasing hormone were unaffected. | 1979 | 115451 |
| the prostaglandin forming cyclooxygenase of ovine uterus: relationship to luteal function. | | 1979 | 115507 |
| neuroendocrine control of gonadotrophin secretion. | | 1979 | 115535 |
| prostaglandins in the control of animal and human reproduction. | current information and theories about the role of prostaglandins in male and female reproduction are reviewed. since more is known about prostaglandins in female reproduction, the activities of the substances in ovulation, luteolysis, anterior pituitary gonadotropin secretion, tubal contractility and egg transport, implantation, and uterine contractility are reported. results of studies in animals and humans are cited in which prostaglandins are used to control reproduction. finally, the suc ... | 1979 | 115536 |
| evidence for fc igg receptors and complement factor c3b receptors in human choroid plexus. | | 1979 | 115630 |
| the nature and role of pregnancy-associated antigens and the endocrinology of early pregnancy in the ewe. | depite descriptions of many of the physiological events of early pregnancy in the ewe, the way in which the immunological and endocrine adjustments are brought about is not well understood. obviously, specific effects--for example, maintenance of the corpus luteum--are brought about by the presence of a conceptus in the uterus. this has led to a search for substances produced by the conceptus or induced by the presence of the conceptus in the uterus which could be involved in establishing pregna ... | 1978 | 115656 |
| differences in the genetic control of primary and secondary antibody responses. | primary and secondary antibody responses to f and s antigens of salmonella typhimurium have been studied in h and l lines of mice genetically selected for primary reponse to sheep erythrocytes (se) (selection i). the range of interline separation obtained (non-specific effect of selection i) was as large as for the selection antigen in the primary response to f antigen and slightly smaller in the primary response to s antigen. for these two antigens the interline difference was reduced after boo ... | 1979 | 115781 |
| polioencephalomalacia in range cattle. | polioencephalomalacia developed in 27 of 225 cattle grazing on 486 hectares of dry, short, grama grass pasture. chemicals in drinking water, toxin from nitrate-utilizing ruminal bacteria, and documented poisonous plants were considered as etiologic agents. attempts to reproduce the disease by injecting mice and dosing sheep with broth filtrate from nitrate-utilizing ruminal bacteria were not successful. mushrooms collected from the pasture and fed to a cow did not reproduce the disease. | 1979 | 115820 |
| role of glucocorticoids in lung maturation. | | 1979 | 115825 |
| enzyme-linked immunosorbent assay for pseudomonas aeruginosa exotoxin a. | an enzyme-linked immunosorbent assay (elisa) is described for pseudomonas aeruginosa exotoxin a. a double antibody sandwich method was used, employing polyvinyl microtiter plates as the solid phase, a primary coat of monospecific rabbit antitoxin serum, an outer layer composed of a horseradish peroxidase-sheep antitoxin immunoglobulin g conjugate, and an ortho-phenylene-diamine substrate. absorbance (optical density) of hydrolyzed end product was read spectrophotometrically at 492 nm. elisa dete ... | 1979 | 115899 |
| radioimmunoassay of human intestinal goblet cell mucin. investigation of mucus from different organs and species. | we have developed a double-antibody radioimmunoassay for the quantitative measurement of human goblet cell mucin (gcm) in order to study intestinal mucus in human and other species. the assay used 3h-labeled mucin as the antigen, rabbit antisera, and sheep anti-rabbit igg antisera as the second antibody. a number of applications of the assay were investigated. a survey of human tissues revealed that mucins of the rectum, colon, and small intestine had identical affinity for the rabbit antibody, ... | 1979 | 115900 |
| expression of a sheep red blood cell receptor by a murine lymphoma. | murine 6c3hed lymphoma cells were found to rosette with sheep red blood cells (srbc). normal c3h lymphocytes did not exhibit this property. this rosetting capacity of 6c3hed cells was found to be an accurate and reproducible means for discriminating between normal and tumor cells. the srbc receptor on these lymphoma cells appeared to be serologically distinct from that expressed by normal human t lymphocytes since reciprocal blocking experiments demonstrated that inhibitory antisera were not cro ... | 1979 | 115920 |
| cross-reactivity of rat, mouse, and human igd. | highly purified sheep anti-rat lymphocyte membrane igd (migd) was used to detect cross-reactivity with the putative murine-delta chain on mouse lymphocytes. cross-reactivity is demonstrated by indirect immunofluorescent staining and by immunoprecipitation of 125i-labeled lymphocyte membrane extracts followed by electrophoresis on 10% polyacrylamide gels. in addition, cross-reactivity of anti-rat-delta with human igd is shown by gel diffusion analysis. the anti-rat-delta reagent stained both ig5a ... | 1979 | 115921 |
| vi. birth defects and genetic disorders. | | 1979 | 115930 |
| cannabinols and feeding in sheep. | marijuana, long used for the euphoria which results, recently has been found to stimulate hunger in humans but in several laboratory animals cannabinoids decrease food intake. sheep, relatively more sensitive to chemicals that affect food intake, were injected iv with the d-and l-isomers of tetrahydrocannabinol and with a 9-aza-cannabinol) 9-ac) (8-(1,2-dimethylheptyl)-5,5-dimethyl-5h-[1]benzopyranol[3,4]pyridin-10-01, hcl) and feeding behavior was monitored. in the first 30 min, food intake was ... | 1979 | 116274 |
| reciprocal relationship between rumen development and intestinal sugar transport capacity in sheep. | | 1979 | 116445 |
| ultrastructural study of globidian parasites infecting the abomasum of sheep in germany. | | 1979 | 116485 |
| dnases in milk and blood sera from different species. | | 1979 | 116487 |
| listeriosis in sheep. listeria monocytogenes excretion and immunological state in sheep in flocks with clinical listeriosis. | | 1979 | 116488 |
| pathogenesis of diarrhoea caused by astrovirus infections in lambs. | experimental infection of 2-day-old gnotobiotic lambs with lamb astrovirus produced mild diarrhoea after an incubation period of about 48 hours. no other clinical symptoms developed. infection was studied by immunofluorescent and histological examination of tissues from the lambs. astroviruses infected only mature villus epithelial cells and subepithelial macrophages in the small intestine, where they produced partial villus atrophy. infected enterocytes were replaced with cuboidal cells from th ... | 1979 | 116623 |
| the failure of prolactin to initiate lactogenesis in the ewe. | infusion of exogenous prolactin (nih-p-s11) at 1 mg/h for 10 h into ewes pretreated for 30 days with oestradiol benzoate and progesterone was unable to initiate milk secretion. similarly primed ewes injected with 10 microgram thyrotrophin releasing hormone also failed to lactate but all ewes injected with dexamethasone (10 mg daily for 5 days) after oestrogen plus progesterone treatment secreted copious quantities of milk. the results suggest that prolactin, itself, is not capable of initiating ... | 1979 | 116641 |
| studies on prolactin. selective reduction of the disulfide bonds of the ovine hormone. | methods for selective reduction of the disulfide bonds in ovine prolactin are reported. cleavage of all three disulfide bonds abolishes biological activity and denatures the hormone. reduction-carbamidomethylation of one or two of the disulfide bridges does not diminish the biological activities in the pigeon crop-sac and mouse mammary gland bioassays. when compared to the native hormone, monomers of these two partially reduced-carbamidomethylated derivatives also show only modest changes in pro ... | 1979 | 116675 |
| mineralization of the enamel of ovine permanent central incisor teeth using microhardness and histological techniques. | | 1979 | 116728 |
| hemagglutinin activity of human plasma fibronectin. | purified human plasma fibronectin at concentrations of about 30 microgram/ml was found to agglutinate trypsin-treated erythrocytes from certain species. the hemagglutination reaction was inhibited by specific antibodies to fibronectin, by relatively low concentrations of polyamines and by higher concentrations of basic amino acids and nonacetylated amino sugars. the divalent cations ca2+ and mg2+ and the chelating agent ethylenediaminetetraacetate did not affect the reaction. none of the neutral ... | 1979 | 116952 |
| origin and developmental patterns of lactase and other glycosidases in sheep amniotic and allantoic fluid. | intestinal lactase activity (with its associated cellobiase, 4-methylumbelliferyl-beta-galactosidase and -beta-glucosidase activities) was used as a specific intestinal marker enzyme to study the release of protein and enzymes of intestinal origin in sheep amniotic fluid during gestation. in amniotic fluid, intestinal lactase activity peaked at 66--85 days of gestation and then decreased with gestation. this enzyme activity was very low or absent in allantoic fluid throughout gestation suggestin ... | 1979 | 117104 |
| a new estimate of sequence divergence of mitochondrial dna using restriction endonuclease mappings. | a new estimate of the sequence divergence of mitochondrial dna in related species using restriction enzyme maps is constructed. the estimate is derived assuming a simple posisson-like model for the evolutionary process and is chosen to maximize an expression which is a reasonable approximation to the true likelihood of the restriction map data. using this estimate, four sets of mitochondrial dna data are analyzed and discussed. | 1979 | 117114 |