| the potential role of polyphenols in the modulation of skin cell viability by aspalathus linearis and cyclopia spp. herbal tea extracts in vitro. | the relationship between polyphenol constituents, antioxidant properties of aqueous and methanol extracts of green tea (camellia sinensis), the herbal teas, rooibos (aspalathus linearis) and honeybush (cyclopia spp.), against skin cell viability was investigated in vitro. | 2016 | 27671741 |
| anti-inflammatory effects of aspalathus linearis and cyclopia spp. extracts in a uvb/keratinocyte (hacat) model utilising interleukin-1α accumulation as biomarker. | ultraviolet b (uvb) radiation is one of the major predisposing risk factors of skin cancer. the anticancer and photoprotective effects of unoxidized rooibos (aspalathus linearis) and honeybush (cyclopia) herbal teas, containing high levels of dihydrochalones and xanthones, respectively, have been demonstrated in skin cancer models in vivo. in the current study, the anti-inflammatory effects of methanol and aqueous extracts of these herbal teas were investigated in a uvb/hacat keratinocyte model ... | 2016 | 27706097 |
| transition rates of selected metals determined in various types of teas (camellia sinensis l. kuntze) and herbal/fruit infusions. | teas and raw materials used as ingredients of herbal and fruit infusions (hfi) were analysed by means of icp-ms for their content of aluminium, arsenic, cadmium, copper, lead and mercury in the dry product and in the infusion. samples of tea (camellia sinensis l. kuntze) were selected to include different origins, types (black, green), leaf grades (whole leaf, broken, fannings, dust) and manufacturing techniques (orthodox, "crush, tear, curl"). the selected hfi raw materials (chamomile, elderber ... | 2017 | 27542446 |
| natural products of relevance in the prevention and supportive treatment of depression. | the use of herbs or their parts: leaves, roots, rhizomes, flowers, seeds, natural strains, as well as extracts or isolated metabolites is becoming more and more popular. natural remedies not only act prophylactically, but also help to alleviate symptoms of many diseases and enhance the overall functioning of the internal organs. many raw materials of natural origin plays a role in treatment of health problems, and also in case of serious diseases such as depression. depression (affective disorde ... | 2016 | 26276913 |
| reduced testosterone production in tm3 leydig cells treated with aspalathus linearis (rooibos) or camellia sinensis (tea). | flavonoids are major compounds of aspalathus linearis and camellia sinensis. they are classified as endocrine disruptors and some have been shown to inhibit testosterone production. tm3 leydig cell cultures were treated with 250-5000 μg ml(-1) a. linearis (unfermented or fermented rooibos) or camellia sinensis (green or black tea) for 24 h in the absence or presence of 6 miu/200 μl human chorionic gonadotropin (hcg). under nonstimulated conditions, all teas tend to decrease testosterone producti ... | 2015 | 24387279 |
| insights on the formulation of herbal beverages with medicinal claims according with their antioxidant properties. | several herbal beverages claim medicinal benefits due to their antioxidant properties. however, operational factors such as the extracted herbal component, preparation method or concentration levels, might influence their biological activity. to assess this effect, the antioxidant activity of beverages prepared with camellia sinensis, aspalathus linearis or cochlospermum angolensis, used solely or mixed with different fruit, plant or algae extracts, was studied using different formulations (bags ... | 2013 | 23459297 |
| the effects of rooibos (aspalathus linearis), green tea (camellia sinensis) and commercial rooibos and green tea supplements on epididymal sperm in oxidative stress-induced rats. | reactive oxygen species (ros) are involved in many physiological functions of mammalian sperm. numerous endogenous antioxidants belonging to both enzymatic and non-enzymatic groups can remove excess ros and prevent oxidative stress (os). this study compares the modulation of os by rooibos, chinese green tea and commercial rooibos and green tea supplements in rat sperm. male wistar rats (n = 60) were supplemented with fermented rooibos, 'green' rooibos, chinese green tea, rooibos supplement, gree ... | 2012 | 22228422 |
| the pharmacological mechanism of angiotensin-converting enzyme inhibition by green tea, rooibos and enalaprilat - a study on enzyme kinetics. | green tea (camellia sinensis l.) and rooibos (aspalathus linearis dahlg.) inhibit angiotensin-converting enzyme (ace) in vitro and in vivo. the ace inhibitor enalaprilat has been described previously as a competitive inhibitor and sometimes as a non-competitive inhibitor. the aim of this study was to investigate the pharmacological mechanism of ace inhibition of green tea and rooibos by enzyme kinetics, and to compare this with enalaprilat. a michaelis-menten kinetics and lineweaver-burk graph s ... | 2012 | 22095883 |
| identification of phenolic compounds in aqueous and ethanolic rooibos extracts (aspalathus linearis) by hplc-esi-ms (tof/it). | rooibos (aspalathus linearis) is a rich source of polyphenols and used to make a mild-tasting tea containing no caffeine, is low in tannins compared to green or black teas, and has antioxidant and antimutagenic/antitumoral properties. in vivo results show that rooibos has beneficial effects upon the lipid profile by decreasing serum triglycerides and cholesterol. in this sense, we have developed a simple and rapid method to separate and characterize simultaneously the polyphenolic compounds in a ... | 2011 | 21509483 |
| clinical efficacy comparison of anti-wrinkle cosmetics containing herbal flavonoids. | herbal anti-wrinkle cosmetics were formulated from ginkgo (ginkgo biloba), a mixture of tea and rooibos (camellia sinensis and aspalathus linearis) and soybean (glycine soja). these extracts were incorporated into the preliminary developed stable gel base with good preference. the gingko formulation was found to be more stable than the formula containing a mixture of tea and rooibos and the soybean formula. clinical efficacies of the ginkgo formula and the formula containing a mixture of tea and ... | 2010 | 20412217 |
| the in vitro effects of rooibos and black tea on immune pathways. | the in vitro effects of aspalathus linearis (rooibos tea) and camellia sinensis (black tea) on biomarkers of specific immune pathways were determined using whole blood culture assays. stimulated and unstimulated whole blood cultures were incubated with tea extracts. enzyme linked immunosorbent assays were used to screen spent culture medium for interleukin-6, interleukin-10 and interferon gamma as biomarkers for inflammation, humoral immunity, and cell mediated immunity, respectively. rooibos an ... | 2010 | 20391028 |
| online gas chromatography combustion/pyrolysis-isotope ratio mass spectrometry (hrgc-c/p-irms) of (+/-)-dihydroactinidiolide from tea ( camellia sinensis ) and rooibos tea ( aspalathus linearis ). | online capillary gas chromatography-isotope ratio mass spectrometry in both the combustion and the pyrolysis modes (hrgc-c/p-irms) was employed to perform authentication studies of the flavoring agent (+/-)-dihydroactinidiolide. thus, the delta(13)c(v-pdb) and delta(2)h(v-smow) values of synthetic (ex synthetic beta-ionone and natural beta-carotene) as well as enzymatically (ex synthetic and natural beta-carotene) produced references were studied in comparison with those of the natural substance ... | 2009 | 19514730 |
| effect of species variation and processing on phenolic composition and in vitro antioxidant activity of aqueous extracts of cyclopia spp. (honeybush tea). | the in vitro antioxidant activity of aqueous extracts prepared from four cyclopia spp. (unfermented and fermented) was assessed using radical (abts *+) scavenging, ferric ion reduction, and inhibition of fe2+-induced microsomal lipid peroxidation as criteria. aqueous extracts of unfermented and fermented aspalathus linearis (rooibos) and camellia sinensis teas (green, oolong, and black) were included as reference samples. qualitative and quantitative differences in phenolic composition were demo ... | 2008 | 18198832 |
| unfermented rooibos tea: quantitative characterization of flavonoids by hplc-uv and determination of the total antioxidant activity. | unfermented rooibos originates from the leaves and the stems of the indigenous south african plant, aspalathus linearis, and it has been reported to have a higher content of flavonoids compared to that of fermented rooibos. the hplc/uv method developed in our laboratory for the analysis of the fermented rooibos was applied to the quantitative characterization of the major flavonoids present in the unfermented rooibos. main compounds determined were aspalathin (49.92 +/- 0.80 mg/g), isoorientin ( ... | 2003 | 14640601 |
| antihemolytic effect of rooibos tea (aspalathus linearis) on red blood cells of japanese quails. | the antihemolytic activity of rooibos and black tea on japanese quail erythrocytes was studied. peroxide and hypotonic hemolysis of the red blood cells of quails, either fed with rooibos tea supplemented food or fed without tea, was performed. long-term consumption of rooibos tea did not change the erythrocyte fragility to either peroxide or hypotonia induced hemolysis. however, rooibos and black teas decreased peroxide induced hemolysis of erythrocytes incubated with each of them, but not hemol ... | 2000 | 11409839 |
| [the effect of rooibos tea on iron absorption]. | a study was carried out to determine if rooibos tea (aspalathus linearis) has a deleterious effect on iron absorption similar to that of ordinary tea (camellia sinensis). three groups of volunteers, each consisting of 10 healthy young men comparable with regard to iron status and body dimensions, were studied. after ingestion of 1 muci 59fe and 16 mg of elemental iron, group a drank rooibos tea, group b ordinary tea and group c boiled water. iron absorption was measured 14 days later with a whol ... | 1979 | 462276 |
| effect of gambisan on the inhibition of adipogenesis in 3t3-l1 adipocytes. | this study was conducted to explore the antiadipogenic effect and possible mechanism of gambisan on 3t3-l1 cells. for quality control, gambisan was standardized by hplc and the standard compounds ephedrine, epigallocatechin-3-gallate, and caffeine were screened. cultured 3t3-l1 cells that had been induced to differentiate were treated with various concentrations of gambisan or its major component extracts (ephedra intermedia schrenk, atractylodes lancea dc., and thea sinensis l.) for 72 hours fo ... | 2013 | 24069055 |
| use of plant extracts for tea pest management in india. | india is the second largest producer of black tea in the world. the biggest challenge for tea growers of india nowadays is to combat pests and diseases. tea crop in india is infested by not less than 720 insect and mite species. at least four sucking pests and six chewing pests have well established themselves as regular pests causing substantial damage to this foliage crop. various synthetic pesticides are widely used for the management of tea pests in india. applications of such large quantity ... | 2016 | 27102124 |
| effect of oxidative phytochemicals on nicotine-stressed umnsah/df-1 cell line. | nicotine is a parasympathomimetic alkaloid found in the nightshade family of plants (solanaceae) and is a cholinergic drug. it acts directly by stimulating the nicotinic or muscarinic receptors or indirectly by inhibiting cholinesterase, promoting acetylcholine release, or by other mechanisms. 3% of tobacco or one cigarette yields 1 mg of nicotine. as nicotine enters the body, it disturbs the healthy functioning of the body. in this study, we isolated umnsah/df-1 cell line from gallus gallus. fo ... | 2014 | 24860736 |
| anti-aging potential of phytoextract loaded-pharmaceutical creams for human skin cell longetivity. | the exposure to ultraviolet radiations (uvr) is the key source of skin sunburn; it may produce harmful entities, reactive oxygen species (ros), leading to aging. the skin can be treated and protected from the injurious effects of ros by using various pharmaceutical formulations, such as cream. cream can be loaded with antioxidants to quench ros leading to photo-protective effects. moreover, modern medicines depend on ethnobotanicals for protection or treatment of human diseases. this review arti ... | 2015 | 26448818 |
| tea, coffee, and cocoa as ultraviolet radiation protectants for the beet armyworm nucleopolyhedrovirus. | the addition of 1% (wt:vol) aqueous extracts of cocoa (theobroma cacao l.) (malvales: malvaceae), coffee (coffea arabica l.) (gentianales: rubiaceae), and green and black tea (camellia sinensis l.) (ericales: theaceae) provided excellent uv radiation protection for the beet armyworm, spodoptera exigua (hübner) (lepidoptera: noctuidae), nucleopolyhedrovirus under laboratory conditions. aqueous extracts of coffee, green tea, and black tea at 0.5% provided 85-100% uv protection, whereas cocoa provi ... | 2009 | 19886440 |
| influence of enamel thickness on bleaching efficacy: an in-depth color analysis. | this study evaluated the influence of different enamel thicknesses and bleaching agents on treatment efficacy in-depth by spectrophotometry color analysis. eighty bovine dental fragments were previously stained in black tea solution and randomly assigned into eight groups (n=10), 1.75mm dentin thickness and different enamel thicknesses as follows: 0.5mm, 1.0mm planned, 1.0mm unplanned (aprismatic enamel), and absence of enamel. the 10% carbamide peroxide (cp) and 35% hydrogen peroxide (hp) bleac ... | 2016 | 27708725 |
| effect of dental pigmentation intensity on the transenamel and transdentinal penetration of hydrogen peroxide. | abastract this study aimed to evaluate the transenamel and transdentinal penetration of hydrogen peroxide (h202) applied to bovine teeth pigmented with black tea at different intensities. the following groups were formed dw: immersion in distilled water; bt100: immersion in an infusion of 1.6 g of black tea per 100 ml distilled water; bt10: immersion in an infusion of 1.6 g black tea per 10 ml distilled water. all groups were immersed for 6 days. to quantify the penetration of h202, the specimen ... | 2017 | 27652700 |
| optical dental whitening efficacy of blue covarine toothpaste in teeth stained by different colors. | evaluate the immediate and cumulative optical whitening efficacy of a blue covarine toothpaste. | 2016 | 26990460 |
| spectrophotometric evaluation of dental bleaching under orthodontic bracket in enamel and dentin. | aware of the diffusion capacity of bleaching in the dental tissues, many orthodontists are subjecting their patients to dental bleaching during orthodontic treatment for esthetic purposes or to anticipate the exchange of esthetic restorations after the orthodontic treatment. for this purpose specific products have been developed in pre-loaded whitening trays designed to fit over and around brackets and wires, with clinical efficacy proven. | 2014 | 25593650 |
| effect of hydro-alcoholic root extract of plumbago zeylanica l alone and its combination with aqueous leaf extract of camellia sinensis on haloperidol induced parkinsonism in wistar rats. | herbal medicines have been used to treat pd in ancient medical systems in asian countries such as india, china, japan and korea based on their own anecdotal or experience-based theories. mucuna pruriens commonly known asvelvet beans, or cow itch, are used in case of spasms associated with parkinsonism. | 2014 | 25206060 |
| effectiveness of dental bleaching in depth after using different bleaching agents. | this study evaluated the effectiveness of low- and high-concentration bleaching agents on enamel and deep dentin. | 2013 | 24455056 |
| efficacy of tooth bleaching with the prior application of a desensitizing agent. | in the present study, we evaluated the efficacy of bleaching on enamel and opposite dentin surfaces using 35% hydrogen peroxide (hp) with the prior application of a desensitizing agent. | 2015 | 24357604 |
| effectiveness of cysteine proteases on protein/pigment film removal. | theaflavin (tf) from the black tea can react to human salivary proline-rich proteins (prps) to form stains on exposed dental surfaces. here, we employed a model of protein/pigment film using tf and dephosphorylated bovine β-casein (dβ-cn), which has an extended conformation, similar to that of salivary prps, on a sensor surface to assess the efficacy of cysteine proteases (cps) including papain, stem bromelain, and ficin, on removing tf bound to dβ-cn and the control tf readsorption on the resid ... | 2013 | 24112727 |
| catechins are not major components responsible for the beneficial effect of camellia sinensis on the ovarian δ-ala-d activity inhibited by cadmium. | cadmium has been associated with a wide spectrum of deleterious effects on the reproductive tissues, including ovary. this investigation evaluated the protective role of camellia sinensis (green, white and red teas) in the cadmium-induced inhibition of ovarian δ-aminolevulinate dehydratase (δ-ala-d) activity in vitro and ex vivo. this study demonstrated that green and white teas restored the cow ovary δ-ala-d activity inhibited by cadmium whereas red tea had no effect in vitro. in addition, gree ... | 2013 | 23376781 |
| effect of beverages on bovine dental enamel subjected to erosive challenge with hydrochloric acid. | this study evaluated by an in vitro model the effect of beverages on dental enamel previously subjected to erosive challenge with hydrochloric acid. the factor under study was the type of beverage, in five levels: sprite® zero low-calorie soda lime (positive control), parmalat® ultra high temperature (uht) milk, ades® original soymilk, leão® ice tea zero ready-to-drink low-calorie peach-flavored black teaand prata® natural mineral water (negative control). seventy-five bovine enamel specimens we ... | 2012 | 23207851 |
| tea creaming in nonfermented teas from camellia sinensis and ilex vomitoria. | tea creaming is the development of a cloudy or hazy appearance in tea and ready-to-drink tea products on cooling and is highly undesirable in the tea beverage industry. commonly associated with fermented black or oolong teas, the objective of this study was to investigate the physicochemical mechanism of the formation of tea cream in nonfermented green tea (camellia sinensis) and a caffeine-containing botanical tea from yaupon holly (ilex vomitoria) that is free of catechin-based polyphenolics. ... | 2012 | 23148671 |
| effects of saponin extracts on air emissions from steers. | a series of experiments were conducted to quantify the effects of saponin extracts from quillaja saponaria molina (qs), yucca schidigera roezl ex ortgies (ys), and camellia sinensis (l.) kuntze (ts) on gaseous emissions from steers (bos taurus). during exp. 1, a control diet [c1, corn (zea mays l.) and corn silage basal diet] was compared with ys1 (c1 + 0.64% dietary dm of ys) and qs1 (c1 + 1.5% dietary dm of qs), with 4 replicates per treatment. during exp. 2, the control diet (c2, corn and cor ... | 2012 | 22665675 |
| sclereids are strong enough to support the delicate corollas: experimental and computational data evidence from camellia sinensis (l.). | sclereids are a fundamental cell type that widely exist in higher plants and are generally thought to have a mechanical function. however, the occurrence of sclereids in the ephemeral corolla has rarely been documented and their biological significance is poorly understood. in this study, flower buds from camellia sinensis at various ontogenetic stages were sampled, cleared, sectioned, stained, and examined using light microscopy to ascertain the morphology and distribution of sclereids and thei ... | 2017 | 28252101 |
| genetic variation of flavonols quercetin, myricetin, and kaempferol in the sri lankan tea (camellia sinensis l.) and their health-promoting aspects. | flavonol glycosides in tea leaves have been quantified as aglycones, quercetin, myricetin, and kaempferol. occurrence of the said compounds was reported in fruits and vegetable for a long time in association with the antioxidant potential. however, data on flavonols in tea were scanty and, hence, this study aims to envisage the flavonol content in a representative pool of accessions present in the sri lankan tea germplasm. significant amounts of myricetin, quercetin, and kaempferol have been det ... | 2016 | 27366737 |
| next-generation sequencing reveals differentially amplified tandem repeats as a major genome component of northern europe's oldest camellia japonica. | northern europe's oldest and largest camellia japonica growing at the pillnitz castle (germany) for over 200 years is of botanical and cultural importance and is a reference for c. japonica molecular scale analysis. in order to provide a fundament for genome analysis of the genus camellia, we characterize the c. japonica tandem repeat fraction, constituting 12.5 % of the pillnitz camellia's genome. a genomic library of the pillnitz c. japonica was produced and illumina sequenced to generate 36 g ... | 2015 | 26582634 |
| development of microsatellite and amplicon length polymorphism markers for camellia japonica l. from tea plant (camellia sinensis) expressed sequence tags. | simple sequence repeats and amplicon length polymorphism markers for camellia japonica were developed, based on camellia sinensis sequences in the national center for biotechnology information database. in total, 2495 gene sequences were used to design 216 primer pairs. to identify amplicon length polymorphism markers, 61 gene loci in 16 camellia individuals were re-sequenced. in total, 10 markers (three expressed sequence tags-simple sequence repeats and seven amplicon length polymorphisms) yie ... | 2009 | 21564753 |
| heterologous nuclear and chloroplast microsatellite amplification and variation in tea, camellia sinensis. | the advantage of the cross transferability of heterologous chloroplast and nuclear microsatellite primers was taken to detect polymorphism among 24 tea (camellia sinensis (l.) o. kuntze) genotypes, including both the assamica and the sinensis varieties. primer information was obtained from the closely related camellia japonica species for four nuclear microsatellites, and from nicotiana tabaccum for seven universal chloroplast microsatellites. all of the nuclear microsatellite loci tested genera ... | 2002 | 12502248 |
| transcriptomic and phytochemical analysis of the biosynthesis of characteristic constituents in tea (camellia sinensis) compared with oil tea (camellia oleifera). | tea plants (camellia sinensis) are used to produce one of the most important beverages worldwide. the nutritional value and healthful properties of tea are closely related to the large amounts of three major characteristic constituents including polyphenols (mainly catechins), theanine and caffeine. although oil tea (camellia oleifera) belongs to the genus camellia, this plant lacks these three characteristic constituents. comparative analysis of tea and oil tea via rna-seq would help uncover th ... | 2015 | 26245644 |
| low caffeine content in novel grafted tea with camellia sinensis as scions and camellia oleifera as stocks. | caffeine, a purine alkaloid, is a major secondary metabolite in tea leaves. the demand for low caffeine tea is increasing in recent years, especially for health reasons. we report a novel grafted tea material with low caffeine content. the grafted tea plant had camellia sinensis as scions and c. oleifera as stocks. the content of purine alkaloids was determined in the leaves of one-year-old grafted tea plants by hplc. we also characterized caffeine synthase (cs), a key enzyme involved in caffein ... | 2015 | 26058159 |
| transcriptomic analysis of the biosynthesis, recycling, and distribution of ascorbic acid during leaf development in tea plant (camellia sinensis (l.) o. kuntze). | ascorbic acid (asa), known as vitamin c, is an essential nutrient for humans and mainly absorbed from food. tea plant (camellia sinensis (l.) o. kuntze) leaves can be a dietary source of asa for humans. however, experimental evidence on the biosynthesis, recycling pathway and distribution of asa during leaf development in tea plants is unclear. to gain insight into the mechanism and distribution of asa in the tea plant leaf, we identified 18 related genes involved in asa biosynthesis and recycli ... | 2017 | 28393854 |
| mothers' consumption of soy drink but not black tea increases the flavonoid content of term breast milk: a pilot randomized, controlled intervention study. | we performed a pilot rct to prove the hypothesis that a controlled ingestion of polyphenol-rich beverages (soy drink, decaffeinated black tea) in nutritive dosages by nursing women has an effect on the composition (flavonoid concentration, total antioxidant capacity) of breast milk. | 2017 | 28391283 |
| tea (camellia sinensis) infusions ameliorate cancer in 4ti metastatic breast cancer model. | tea (camellia sinensis) infusions are widely consumed beverages with numerous health benefits. however, physiological and molecular responses mediating these activities are poorly understood. | 2017 | 28388918 |
| a simple, enzymatic biotransformation method using fresh green tea leaves efficiently generates theaflavin-containing fermentation water that has potent physiological functions in mice and humans. | the polyphenolic compound theaflavin, the main red pigment in black tea, possesses many beneficial properties, such as fat-reducing and glucose-lowering capabilities. to produce theaflavin-containing fermentation water on a large scale, we have developed a simple, inexpensive, and selective enzymatic biotransformation method to obtain sufficient levels from fresh green tea leaves. subsequent administration of theaflavin-containing fermentation water to obese mice on a high-fat diet inhibited bod ... | 2017 | 28381812 |
| an rna-seq transcriptome analysis revealing novel insights into aluminum tolerance and accumulation in tea plant. | the tea plant ( camellia sinensis l. o. kuntze) is a high aluminum (al) tolerant and accumulator species. candidate genes related to al tolerance in tea plants were assembled based on de novo transcriptome analysis. the homologs implied some common and distinct al-tolerant mechanism between tea plants and rice, arabidopsis and buckwheat. in addition to high al tolerance, the tea plant exhibits good performance exposure to a proper al level, and accumulates high al in the leaves without any toxic ... | 2017 | 28365842 |
| aluminum induced physiological and proteomic responses in tea (camellia sinensis) roots and leaves. | tea (camellia sinensis (l.) o. kuntze), is an aluminum (al) hyperaccumulator and grows well in acid soils. although al-induced growth of tea plant has been studied, the proteomic profiles of tea plants in response to al are unclear. in the present study, the proteomic profiles in tea roots and leaves under al stress were investigated using itraq proteomics approach. in total, 755 and 1059 differentially expressed proteins were identified in tea roots and leaves, respectively. kegg enrichment ana ... | 2017 | 28364710 |
| an on-line hplc system for detection of antioxidant compounds in some plant extracts by comparing three different methods. | echinacea (echinacea purpurea), green tea (camellia sinensis) and yaylacayi (thymus praecox opiz subsp. grossheimii (ronniger) jalas) are herbs used in traditional medicine because of their beneficial health effects. a high performance liquid chromatography (hplc) post-column method was developed by coupling hplc with on-line antioxidant assays using diode array (dad) and ultraviolet (uv) detectors. thus antioxidant compounds and fifteen phenolic standards were detected in echinacea, green tea a ... | 2017 | 28359985 |
| effective subcritical butane extraction of bifenthrin residue in black tea. | as a natural and healthy beverage, tea is widely enjoyed; however, the pesticide residues in tea leaves affect the quality and food safety. to develop a highly selective and efficient method for the facile removal of pesticide residues, the subcritical butane extraction (sbe) technique was employed, and three variables involving temperature, time and extraction cycles were studied. the optimum sbe conditions were found to be as follows: extraction temperature 45 °c, extraction time 30 min, numbe ... | 2017 | 28358319 |
| γ-aminobutyric acid (gaba) accumulation in tea (camellia sinensis l.) through the gaba shunt and polyamine degradation pathways under anoxia. | γ-aminobutyric acid (gaba) is an important bioactive component of tea (camellia sinensis) providing various health benefits. we studied gaba accumulation via the gaba shunt and polyamine degradation pathways under anoxia in tea leaves. anoxia caused a ∼20-fold increment in gaba concentration, relative to fresh tea leaves. this increment was due to the increase of glutamate decarboxylase and diamine oxidase activities. genes involved in gaba formation, such as csgad1 and csgad2, were significantl ... | 2017 | 28355482 |
| black tea high-molecular-weight polyphenol-rich fraction promotes hypertrophy during functional overload in mice. | mitochondria activation factor (maf) is a high-molecular-weight polyphenol extracted from black tea that stimulates training-induced 5' adenosine monophosphate-activated protein kinase (ampk) activation and improves endurance capacity. originally, maf was purified from black tea using butanol and acetone, making it unsuitable for food preparation. hence, we extracted a maf-rich sample "e80" from black tea, using ethanol and water only. here, we examined the effects of e80 on resistance training. ... | 2017 | 28353662 |
| characterization of the potent odorants contributing to the characteristic aroma of matcha by gas chromatography-olfactometry techniques. | the odorants contributing to the characteristic aroma of matcha were investigated by analysis of the headspace samples and the volatile fractions prepared by a combination of solvent extraction and the safe techniques using three matcha powders of different grades (high, medium, and low). gas chromatography-olfactometry of the headspace samples (gco-h) and aroma extract dilution analysis (aeda) applied to the volatile fractions revealed 16 (fd factor ≥1) and 39 (fd factor ≥4(3)) odor-active peak ... | 2017 | 28343386 |
| total volume and composition of fluid intake and mortality in older women: a cohort study. | the health benefits of 'drinking at least 8 glasses of water a day" in healthy individuals are largely unproven. we aimed to examine the relationship between total fluid and the sources of fluid consumption, risk of rapid renal decline, cardiovascular disease (cvd) mortality and all-cause mortality in elderly women. | 2017 | 28341683 |
| novel acylated flavonol tetraglycoside with inhibitory effect on lipid accumulation in 3t3-l1 cells from lu'an guapian tea and quantification of flavonoid glycosides in six major processing types of tea. | a novel acylated flavonol tetraglycoside, kaempferol 3-o-[(e)-p-coumaroyl-(1→2)][α-l-arabinopyranosyl-(1→3)][β-d-glucopyranosyl (1→3)-α-l-rhamnopyranosyl(1→6)]-β-d-glucopyranoside (camellikaempferoside c, 1), together with 2 flavonols and 18 flavone and flavonol glycosides (fgs) (2-21) was isolated from the green tea lu'an guapian (camellia sinensis l.o. kuntze). their structures were identified by spectroscopic and chemical methods. four acylated fgs (1, 7, 8, 9) were found to inhibit the proli ... | 2017 | 28339202 |
| metabolic flux redirection and transcriptomic reprogramming in the albino tea cultivar 'yu-jin-xiang' with an emphasis on catechin production. | in this study, shade-induced conversion from a young pale/yellow leaf phenotype to a green leaf phenotype was studied using metabolic and transcriptomic profiling and the albino cultivar 'yu-jin-xiang' ('yjx') of camellia sinensis for a better understanding of mechanisms underlying the phenotype shift and the altered catechin and theanine production. shaded leaf greening resulted from an increase in leaf chlorophyll and carotenoid abundance and chloroplast development. a total of 1,196 different ... | 2017 | 28332598 |
| black tea supplementation augments redox balance in rats: relevance to aging. | several health beneficial effects have been attributed to tea consumption, most of the effects are due to the strong antioxidant property of tea catechins. the present study evaluates the effect of black tea extract (bte) supplementation on the redox balance of rats at different stages in their life span. we have evaluated erythrocyte and plasma redox status in young (4 months), middle-aged (12 months) and old-aged (24 months) male wistar rats, by quantifying an array of parameters linked to red ... | 2017 | 28332429 |
| enzyme-assisted supercritical fluid extraction: an alternative and green technology for non-extractable polyphenols. | this contribution proposes an enzyme-assisted eco-friendly process for the extraction of non-extractable polyphenols (nepps) from black tea leftover (btlo), an underutilized tea waste. btlo hydrolyzed with various enzyme formulations was extracted using supercritical carbon dioxide and ethanol as co-solvent (sc-co2 + etoh). a conventional solvent extraction (cse) was performed using etoh + h2o (80:20, v/v) for comparison purposes. the results revealed that hydrolysis of btlo with 2.9% (w/w) kemz ... | 2017 | 28331956 |
| a putative 12-oxophytodienoate reductase gene csopr3 from camellia sinensis, is involved in wound and herbivore infestation responses. | 12-oxophytodienoate reductase (opr) is a key enzyme in the biosynthesis of jasmonic acid (ja), which plays an important role in plant defense responses. although multiple isoforms of oprs have been identified in various annual herbaceous plants, genes encoding these enzymes in perennial woody plants have yet to be fully investigated. in the tea plant, camellia sinensis (l.), no opr genes have been isolated, and their possible roles in tea plant development and defense mechanism remain unknown. i ... | 2017 | 28322995 |
| integrated transcriptome and metabolic analyses reveals novel insights into free amino acid metabolism in huangjinya tea cultivar. | the chlorotic tea variety huangjinya, a natural mutant, contains enhanced levels of free amino acids in its leaves, which improves the drinking quality of its brewed tea. consequently, this chlorotic mutant has a higher economic value than the non-chlorotic varieties. however, the molecular mechanisms behind the increased levels of free amino acids in this mutant are mostly unknown, as are the possible effects of this mutation on the overall metabolome and biosynthetic pathways in tea leaves. to ... | 2017 | 28321230 |
| metabolomics analysis reveals the metabolic and functional roles of flavonoids in light-sensitive tea leaves. | as the predominant secondary metabolic pathway in tea plants, flavonoid biosynthesis increases with increasing temperature and illumination. however, the concentration of most flavonoids decreases greatly in light-sensitive tea leaves when they are exposed to light, which further improves tea quality. to reveal the metabolism and potential functions of flavonoids in tea leaves, a natural light-sensitive tea mutant (huangjinya) cultivated under different light conditions was subjected to metabolo ... | 2017 | 28320327 |
| effect of green tea (camellia sinensis) extract and pre-freezing equilibration time on the post-thawing quality of ram semen cryopreserved in a soybean lecithin-based extender. | the aim of this study was to determine the effect of camellia sinensis extract as antioxidant supplement and pre-freezing equilibration times in a soybean lecithin extender for freezing ram semen. in this study, a total of 20 ejaculates were collected from four ghezel rams and diluted with extenders (1.5% soybean lecithin, 7% glycerol) containing no supplements (control) and camellia sinensis extract (5, 10, and 15 mg/l) and cryopreserved, immediately after thermal equilibrium was reached at 5 ° ... | 2016 | 28314435 |
| draft genome sequence of endophytic herbaspirillum sp. strain wt00c, a tea plant growth-promoting bacterium. | endophytic herbaspirillum sp. strain wt00c was isolated from tea plant (camellia sinensis l.). here, we report the 6.08 mb draft genome sequence of this strain, providing bioinformation about its agronomic benefits and capability to reduce selenate/selenite into red elemental selenium. | 2017 | 28302787 |
| alcohol induced hepato cardiotoxicity and oxidative damage in rats: the protective effect of n-butanol extract of green tea (camellia sinensis (l.) kuntze). | the principal aim of this study was to investigate the oxidative effects of acute alcohol consumption on the functions of the heart and the liver and the possible modification of this effect by phenolic compounds from n-butanol extract of camellia sinensis supplementation. | 2017 | 28294073 |
| green tea and its anti-angiogenesis effects. | the development of new blood vessels from a pre-existing vasculature (also known as angiogenesis) is required for many physiological processes including embryogenesis and post-natal growth. however, pathological angiogenesis is also a hallmark of cancer and many ischaemic and inflammatory diseases. the pro-angiogenic members of the vegf family (vascular endothelial growth factor family), vegf-a, vegf-b, vegf-c, vegf-d and placental growth factor (plgf), and the related receptors, vegfr-1, vegfr- ... | 2017 | 28292023 |
| theabrownin inhibits cell cycle progression and tumor growth of lung carcinoma through c-myc-related mechanism. | green tea, the fresh leaves of camellia sinensis, is not only a health-promoting beverage but also a traditional chinese medicine used for prevention or treatment of cancer, such as lung cancer. theabrownin (tb) is the main fraction responsible for the medicinal effects of green tea, but whether it possesses anti-cancer effect is unknown yet. this study aimed to determine the in vitro and in vivo anti-lung cancer effect of tb and explore the underlying molecular mechanism, by using a549 cell lin ... | 2017 | 28289384 |
| intelligent evaluation of color sensory quality of black tea by visible-near infrared spectroscopy technology: a comparison of spectra and color data information. | instrumental test of black tea samples instead of human panel test is attracting massive attention recently. this study focused on an investigation of the feasibility for estimation of the color sensory quality of black tea samples using the vis-nir spectroscopy technique, comparing the performances of models based on the spectra and color information. in model calibration, the variables were first selected by genetic algorithm (ga); then the nonlinear back propagation-artificial neural network ... | 2017 | 28279828 |
| camellia sinensis l. extract and its potential beneficial effects in antioxidant, anti-inflammatory, anti-hepatotoxic, and anti-tyrosinase activities. | the aims of this study were to investigate the potential benefits of antioxidant, anti-inflammatory, anti-hepatotoxic, and anti-tyrosinase activities of a methanolic extract of fresh tea leaves (fte) (camellia sinensis l.). the antioxidant capacity was investigated using three different methods at different temperatures. the anti-inflammatory activity was studied in vitro by the inhibition of 5-lipoxygenase assay. the anti-hepatotoxic effect was investigated in ccl₄-induced liver injury in rats. ... | 2017 | 28273866 |
| molecular cloning and characterization of galactinol synthases in camellia sinensis with different responses to biotic and abiotic stressors. | galactinol synthase (gols) is a key biocatalyst for the synthesis of raffinose family oligosaccharides (rfos). rfos accumulation plays a critical role in abiotic stress adaptation, but the relationship between expression of gols genes and biotic stress adaptation remains unclear. in this study, two csgols genes were found to be highly up-regulated in a transcriptome library of ectropic oblique-attacked camellia sinensis. three complete csgols genes were then cloned and characterized. gene transc ... | 2017 | 28271712 |
| synergisms in alpha-glucosidase inhibition and antioxidant activity of camellia sinensis l. kuntze and eugenia uniflora l. ethanolic extracts. | camellia sinensis, the most consumed and popular beverages worldwide, and eugenia uniflora, a brazilian native species, have been already confirmed to have beneficial effects in the treatment of diabetes mellitus. however, their potential acting together against an enzyme linked to this pathology has never been exploited. | 2017 | 28250662 |
| study of the stereochemistry and oxidation mechanism of plant polyphenols, assisted by computational chemistry. | in recent years, plant polyphenols have attracted great attention due to their wide range of biological activities. certain kinds of polyphenols have complex structures; therefore, it is difficult to elucidate their total structure, including stereochemistry. in this study, we reinvestigated the stereostructures of two major c-glycosidic ellagitannins contained in quercus plants, vescalagin and castalagin, and revised their stereostructures based on theoretical calculations of spectroscopic data ... | 2017 | 28250332 |
| antimutagenic and anticlastogenic effects of turkish black tea on ta98 and ta100 strains of salmonella typhimurium (in vitro) and mice (in vivo). | black tea has been reported to have significant antimutagenic and anticarcinogenic properties associated with its polyphenols theaflavins (tf) and thearubigins (tr). similarly, turkish black tea (tbt) also contains a considerable amount of tf and tr. | 2017 | 28245735 |
| developmental processes and responses to hormonal stimuli in tea plant (camellia sinensis) leaves are controlled by grf and gif gene families. | tea plant (camellia sinensis (l.) o. kuntze) is an important leaf-type woody crop used for producing of non-alcoholic beverages worldwide. the growth-regulating factor (grf) transcription factors cooperated with grf-interacting factor (gif) transcriptional coactivators positively regulate leaf development. in the present study, six grf and two gif genes were identified and characterized in the leaf transcriptome of c. sinensis, respectively. the alignment results showed that the feature structur ... | 2017 | 28236273 |
| combined small rna and degradome sequencing reveals complex microrna regulation of catechin biosynthesis in tea (camellia sinensis). | micrornas are endogenous non-coding small rnas playing crucial regulatory roles in plants. tea, a globally popular non-alcoholic drink, is rich in health-enhancing catechins. in this study, 69 conserved and 47 novel mirnas targeting 644 genes were identified by high-throughout sequencing. predicted target genes of mirnas were mainly involved in plant growth, signal transduction, morphogenesis and defense. to further identify targets of tea mirnas, degradome sequencing and rna ligase-mediated rap ... | 2017 | 28225779 |
| sub-chronic indomethacin treatment and its effect on the male reproductive system of albino rats: possible protective role of black tea extract. | indomethacin is commonly used as a nonsteroidal anti-inflammatory drug (nsaid) to treat inflammation, arthritis and joint pains. unfortunately, it has a wide range of adverse effects on the physiological system, including gonads. this study aimed to assess possible beneficial effects of black tea extract (bte) against indomethacin-induced alteration of gonadal hormone levels in male rats. | 2017 | 28222030 |
| enantiomeric and quantitative analysis of volatile terpenoids in different teas (camellia sinensis). | volatile terpenoids play important roles in the formation of tea aroma quality due to their pleasant scents and low odor thresholds. most volatile terpenoids contain stereogenic centers, which results in various stereo distributions of their enantiomers and diastereoisomers in different types of tea. however, the distribution characteristics of terpenoid enantiomers in teas were still unclear, which poses an obstacle to the scientific understanding of tea aroma. in this work, a new and efficient ... | 2017 | 28216091 |
| a rapid uplc method for simultaneous analysis of caffeine and 13 index polyphenols in black tea. | | 2017 | 28203771 |
| xanthine alkaloids: occurrence, biosynthesis, and function in plants. | caffeine is a xanthine alkaloid found in non-alcoholic beverages such as tea, coffee, and cocoa. it was discovered in tea and coffee in the 1820s, but it was not until 2000 that details of molecular events associated with caffeine biosynthesis began to be unraveled. reviewed are the occurrence of xanthine alkaloids in the plant kingdom and the elucidation of the caffeine biosynthesis pathway, providing details of the n-methyltransferases, belonging to the motif b' methyltransferase family, which ... | 2017 | 28194561 |
| black tea volatiles fingerprinting by comprehensive two-dimensional gas chromatography - mass spectrometry combined with high concentration capacity sample preparation techniques: toward a fully automated sensomic assessment. | tea prepared by infusion of dried leaves of camellia sinensis (l.) kuntze, is the second world's most popular beverage, after water. its consumption is associated with its chemical composition: it influences its sensory and nutritional quality addressing consumer preferences, and potential health benefits. this study aims to obtain an informative chemical signature of the volatile fraction of black tea samples from ceylon by applying the principles of sensomics. in particular, several high conce ... | 2017 | 28193425 |
| epidemiology, environmental risk factors and genetics of parkinson's disease. | parkinson's disease (pd) is a frequent neurodegenerative disease with a premotor phase that lasts several years. risk factors that have been linked to pd are tobacco, caffeine, black tea, pesticides and calcium channel blockers. some risk factors may be due to inverse causality (e.g. changes in personality during the premotor phase). the genetics of pd are complex with a contribution of mendelian (e.g. snca, lrrk2, parkin, pink1,…) and non-mendelian factors (e.g. single nucleotide polymorphisms) ... | 2017 | 28189372 |
| tea consumption and risk of bladder cancer: a dose-response meta-analysis. | background and objective: controversial results of the association between tea (black tea, green tea, mate, and oolong tea) consumption and risk of bladder cancer were reported among epidemiological studies. thus, we performed a meta-analysis of observational studies to investigate the association. methods: we searched the pubmed and embase for studies of tea consumption and bladder cancer that were published in any language up to march, 2016. cohort or case-control studies were included in the ... | 2016 | 28167914 |
| resveratrol and epigallocatechin-3-gallate addition to thawed boar sperm improves in vitro fertilization. | thawing is one of the most delicate process after semen cryopreservation as spermatozoa pass from a dormant metabolic stage to a sudden awakening in cellular metabolism. the rapid oxygen utilization leads to an overproduction of reactive oxygen species that can damage sperm cells, thus causing a significant decrease of fertilizing potential of frozen-thawed spermatozoa. resveratrol (res) is a natural grape-derived phytoalexin and epigallocatechin-3-gallate (egcg) is the major polyphenol in green ... | 2017 | 28166993 |
| proteolysis of chloroplast proteins is responsible for accumulation of free amino acids in dark-treated tea (camellia sinensis) leaves. | shade management (dark treatment) on tea (camellia sinensis) plants is a common approach to improve free amino acids in raw materials of tea leaves. however, the reason for amino acid accumulation in dark-treated tea leaves is still unknown. in the present study, dark treatment significantly increased content of free amino acids and reduced content of soluble proteins in tea leaves. quantitative proteomics analysis showed that most enzymes involved in biosyntheses of amino acids were down-accumu ... | 2017 | 28163235 |
| green tea (camellia sinensis) protects against arsenic neurotoxicity via antioxidative mechanism and activation of superoxide dismutase activity. | chronic arsenic-exposure even at a low-dose results in the neural impairment and motor/cognitive dysfunction. however, several preventive approaches are made mainly against hepatic/gastrointestinal damages. only a few investigations postulate therapeutic strategies for neural anomalies. here, the protective role of green tea (camellia sinensis or cs; 10mg/ml aqueous) has been evaluated against arsenic-induced (0.6ppm/100g bw/28 days) cerebral/cerebellar tissue degeneration, oxidative-threats and ... | 2017 | 28155600 |
| protective effect of green tea (camellia sinensis (l.) kuntze) against prostate cancer: from in vitro data to algerian patients. | green tea (gt) has been studied for its effects as antioxidant and cancer-preventive agent. epidemiological studies showed that gt consumption decreases the risk for prostate cancer (pc). to investigate whether erythrocyte oxidative stress (os) is associated with pc and whether daily consumption of gt improves the oxidative phenotype, we performed a study in a group of algerian pc patients, preceded by an in vitro study to characterize composition and antioxidant/antiproliferative activities of ... | 2017 | 28133488 |
| tea polyphenols dominate the short-term tea (camellia sinensis) leaf litter decomposition. | polyphenols are one of the most important secondary metabolites, and affect the decomposition of litter and soil organic matter. this study aims to monitor the mass loss rate of tea leaf litter and nutrient release pattern, and investigate the role of tea polyphenols played in this process. high-performance liquid chromatography (hplc) and classical litter bag method were used to simulate the decomposition process of tea leaf litter and track the changes occurring in major polyphenols over eight ... | 2017 | 28124839 |
| safety evaluation of fluoride content in tea infusions consumed in the azores-a volcanic region with water springs naturally enriched in fluoride. | tea is the second most commonly consumed beverage in the world. it is well recognized that the consumption of tea in high quantities can promote the development of fluorosis. the main objective of this study is to estimate the exposure to fluoride in the azores through drinking tea prepared with water from different volcanic locations, by i) investigating the fluoride (f) content of various commercial brands of tea (camellia sinensis) marketed in azores and ii) comparing tea releasing rates of f ... | 2017 | 28120305 |
| an appraisal of drug-drug interactions with green tea (camellia sinensis). | this review summarizes published in vitro, animal, and clinical studies investigating the effects of green tea (camellia sinensis) extract and associated catechins on drug-metabolizing enzymes and drug transporters. in vitro studies suggest that green tea extract and its main catechin, (-)-epigallocatechin-3-gallate, to varying degrees, inhibit the activity of cyp1a1, cyp1a2, cyp2b6, cyp2c8, cyp2c9, cyp2d6, and cyp3a4. ugt1a1 and ugt1a4 isoforms were also inhibited by (-)-epigallocatechin-3-gall ... | 2017 | 28118673 |
| optimization of the production of 1-phenylethanol using enzymes from flowers of tea (camellia sinensis) plants. | 1-phenylethanol (1pe) can be used as a fragrance in food flavoring and cosmetic industries and as an intermediate in the pharmaceutical industry. 1pe can be synthesized from acetophenone, and the cost of 1pe is higher than the cost of acetophenone. therefore, it is important to establish an effective and low-cost approach for producing 1pe. our previous studies found that tea (camellia sinensis) flowers, which are an abundant and waste resource, contained enzymes that could transform acetophenon ... | 2017 | 28098803 |
| preclinical and potential applications of common western herbal supplements as complementary treatment in parkinson's disease. | parkinson's disease (pd) is a neurological disorder with a complex pathological etiology, which is not fully understood. progression of pd may be the result of a buildup of iron in the substantia nigra, microglia-mediated neuroinflammation, dysfunctional mitochondria, or abnormal protein handling. dopamine is the main neurotransmitter affected, but as the disease progresses, a decrease in all the brain's biogenic amines occurs. current medication used in the treatment of pd aims to prevent the b ... | 2017 | 28095073 |
| bottom-up synthesis of carbon nanoparticles with higher doxorubicin efficacy. | nanomedicine requires intelligent and non-toxic nanomaterials for real clinical applications. carbon materials possess interesting properties but with some limitations due to toxic effects. interest in carbon nanoparticles (cnps) is increasing because they are considered green materials with tunable optical properties, overcoming the problem of toxicity associated with quantum dots or nanocrystals, and can be utilized as smart drug delivery systems. using black tea as a raw material, we synthesi ... | 2017 | 28093297 |
| are sleep duration, midpoint of sleep and sleep quality associated with dietary intake among bavarian adults? | only few epidemiologic studies examined sleep characteristics in relation to dietary behaviour. our aim was to analyse associations of sleep duration, midpoint of sleep and sleep quality with dietary intake among the bavarian population. | 2017 | 28074892 |
| anxiolytic activity of aqueous extract of camellia sinensis in rats. | the present study was undertaken to evaluate anxiolytic effect of camellia sinensis (cs) and possible mechanism on acute and chronic administration in rats. | 2017 | 28066107 |
| black tea consumption improves postprandial glycemic control in normal and pre-diabetic subjects: a randomized, double-blind, placebo-controlled crossover study. | postprandial glycemic control is important for prevention of diabetes. black tea consumption may improve postprandial glycemic control. the major bioactive compounds are polyphenols, black tea polymerized polyphenol (btpp).this study examined the effect of black tea consumption on postprandial blood glucose and insulin response following sucrose loading in normal and pre-diabetes subjects. | 2017 | 28049262 |
| in vivo anti-arthritic efficacy of camellia sinensis (l.) in collagen induced arthritis model. | rheumatoid arthritis (ra), an autoimmune inflammatory disorder with synovial hyperplasia, destruction of cartilage, bone damage is often associated with risk of infections. such risk could be attributed towards usage of immunosuppressive agents. thus, the present study was undertaken to evaluate the anti-arthritic efficacy of aquo-alcoholic extract of camellia sinensis (l.). | 2017 | 28049097 |
| green tea (camellia sinensis) for patients with knee osteoarthritis: a randomized open-label active-controlled clinical trial. | green tea is known as a dietary supplement and a novel functional food worldwide. since there are increasing preclinical evidence about efficacy of green tea for treating osteoarthritis, this study has aimed at assessing its efficacy and safety for patients with knee osteoarthritis. | 2016 | 28038881 |
| isolation of chs gene from brunfelsia acuminata flowers and its regulation in anthocyanin biosysthesis. | chalcone synthase gene (bachs) from brunfelsia acuminata flowers was isolated using rt-pcr and race. the coding region of the gene is 1425-bp with an open reading frame of 1170-bp, 73-bp 5'utr, and 172-bp 3'utr. its deduced protein does not have a signal peptide but does contain a cond_enzyme superfamily domain, and consists of 389 amino acids with a predicted molecular mass of 42,699 da and a pi of 6.57. the deduced amino acid sequence of bachs shares 90%, 88%, 85%, 84% and 79% identity with ch ... | 2016 | 28036083 |
| acute black tea consumption improves cutaneous vascular function in healthy middle-aged humans. | dietary flavonoids, such as those present in black tea, are associated with reduced risk of cardiovascular disease (cvd), possibly through improving nitric oxide (no) mediated vascular function. the aim of this study was to examine the effect of acute black tea ingestion on cutaneous microvascular function. | 2016 | 28034564 |
| htp nutraceutical screening for histone deacetylase inhibitors and effects of hdacis on tumor-suppressing mirnas by trichostatin a and grapeseed (vitis vinifera) in hela cells. | aggressive tumor malignancies are a consequence of delayed diagnosis, epigenetic/phenotype changes and chemo-radiation resistance. histone deacetylases (hdacs) are a major epigenetic regulator of transcriptional repression, which are highly overexpressed in advanced malignancy. while original chemotherapy drugs were modeled after phytochemicals elucidated by botanical screenings, hdac inhibitors (hdaci) such as apicidin, trichostatin a (tsa) and butyrate were discovered as products of fungus and ... | 2017 | 28031235 |
| global transcriptional analysis reveals the complex relationship between tea quality, leaf senescence and the responses to cold-drought combined stress in camellia sinensis. | in field conditions, especially in arid and semi-arid areas, tea plants are often simultaneously exposed to various abiotic stresses such as cold and drought, which have profound effects on leaf senescence process and tea quality. however, most studies of gene expression in stress responses focus on a single inciting agent, and the confounding effect of multiple stresses on crop quality and leaf senescence remain unearthed. here, global transcriptome profiles of tea leaves under separately cold ... | 2016 | 28018394 |
| isolation and expression features of hexose kinase genes under various abiotic stresses in the tea plant (camellia sinensis). | hexokinases (hxks, ec 2.7.1.1) and fructokinases (frks, ec 2.7.1.4) play important roles in carbohydrate metabolism and sugar signaling during the growth and development of plants. however, the hxks and frks in the tea plant (camellia sinensis) remain largely unknown. in this manuscript, we present the molecular characterization, phylogenetic relationships, conserved domains and expression profiles of four hxk and seven frk genes of the tea plant. the 11 deduced cshxk and csfrk proteins were gro ... | 2017 | 28013175 |
| anti-proliferative and apoptosis-inducing effect of theabrownin against non-small cell lung adenocarcinoma a549 cells. | with the highest cancer incidence rate, lung cancer, especially non-small cell lung cancer (nsclc), is the leading cause of cancer death in the world. tea (leaves of camellia sinensis) has been widely used as a traditional beverage beneficial to human health, including anti-nsclc activity. theabrownin (tb) is one major kind of tea pigment responsible for the beneficial effects of tea liquor. however, its effect on nsclc is unknown. the aim of the present study was to evaluate anti-proliferative ... | 2016 | 27994550 |