| [role of colicinogenicity in the mechanism of the antagonistic action of sonne and flexner shigellae]. | | 1976 | 797188 |
| [ultrastructural changes in mucosa of the distal portion of the large intestine of patients with dysentery]. | the ultrastructure of the mucosa of the large intestine was studied in 10 patients with acute dysentery. the group of patients included 7 women and 3 men aged 17--50 years. diagnosis was confirmed in all cases bacteriologically (by isolation of sonne shigella in 4 patients and flexner shigella in 6 patients). the electron-microscopy study of bioptats of the mucosa showed that in the inflammatory process all its cells--prismatic, gobletcells, and enterochromaffin -- took part, although not in the ... | 1976 | 797360 |
| r factors derived from shigella flexneri strains. | of 2492 shigelle flexneri strains isolated from dysenteric patients in hungary in the years 1972-1974, 767 (30.8%) were resistant to 1-5 antibiotics. resistance was due to r factors in 79.2% of the strains. fertility inhibition experiments with f specific phages showed r factors to be fi+ in 12.9% and fi- and 87.1%. of the antibiotic markers, the chloramphenicol-tetracycline resistance determinant was the most common (46.4%). chloramphenicol resistance determinants were carried out by fi- r fact ... | 1976 | 798470 |
| restriction and modification of shigella flexneri phages by r factors. | out of 420 r factors derived from shigella flexneri strains, 50.8% restricted escherichia coli and s. flexneri phages. phage restriction was produced both by fi- and fi+ r factors. the r factors were divided into nine groups on the basis of the efficiency of plating of s. flexneri phages. changes of phage types were produced by transferring r factors of different restrictive types. the changes offered some information concerning the evolution of phage types. studies on phage modification support ... | 1976 | 798471 |
| [chemotypes of "shigella flexneri" r mutants and related phage receptors. ii. -- localization of phage receptors (author's transl)]. | receptor sites for phages fp3, v, p1kcvir, h+, c21, t4, t3, t7 and 6sr have been investigated, by comparing the lytic activity of these phages on r mutants of strain f6 (f6r) and of various serotypes (fh) of shigella flexneri with their inhibition by the lipopolysaccharides isolated from these mutants. the results suggest the following localizations for the receptor sites: phage fp3: lipid a-kdo; phage v: heptose or glucose; phage c21: heptose-glucose; phages h+, p1kcvir, t4 and t3: glucose; pha ... | 1976 | 798512 |
| [chemotypes of "shigella flexneri" r mutants and related phage receptors. i. -- chemical study of the lipopolysaccharides (author's transl)]. | the f6r rough mutants isolated from shigella flexneri f6s, serotype 5b, and the fh rough mutants, derived from other serotypes of s. flexneri, were chemotyped according to the chemical analysis of their lipopolysaccharides. further, the following stages of lipopolysaccharide core biosynthesis in s. flexneri have been established: --(kdo)3--heptose--heptose--glucose--galactose; the last three stages are: either --glucose--glucosamine--glucose, or --glucosamine--glucose--glucose. the results of th ... | 1976 | 798513 |
| [substantiation for the kanamycin treatment of certain diseases, taking into account its concentration at the sites of localization of the causative agent (an experimental study)]. | kanamycin concentration in the inflammatory foci was studied on experimental models of pneumonia, maxillary sinusitis and acute dysentery. the kanamycin levels in the sites of the pathogen localization were lower than those in the same tissues of healthy animals. the antibiotic dose should be chosen with the account of its concentration in the focus of the pathogen localization rather than in the blood serum. | 1976 | 798542 |
| [antibodies to enteropathogenic bacteria in the saliva of patients with different forms of acute intestinal diseases and healthy subjects]. | | 1976 | 799368 |
| [production and characteristics of glycerin mutants of s. typhimurium]. | s. typhimurium glycerine mutants-gly 90 and gly 87 were obtained under the action of ethylmethanesulfonate. the mutants obtained were characterized by the site of block in the course of glycerine utilization:gly 90 mutant bore the mutation in the glp k-gene, this leading to the defect by glycerokinase-the enzyme of the first stage of glycerine metabolism; gly 87 mutant had derangements in the other stage of glycerine utilization. both mutants lost their capacity to induce keratoconjunctivitis in ... | 1976 | 799451 |
| [distribution of lysotypes and study of antibiotic sensitivity of shigella flexneri 2 isolated in iran]. | 152 strains of shigella flexneri 2 isolated from the stools of patients having sporadic bacillary dysenteria have been studied for their phage types as well as for the presence of transferable resistance factor. the distribution of the phage types has shown a high predominance of lysotype 12 (67%). proportion of shigella flexneri 2 strains resistant to one or several antibiotics has been highest in the years 1968 and 1973. the most frequent transferable resistance pattern was found to be (tc, cm ... | 1976 | 799541 |
| generalized transduction of shigella flexneri by converting phage pe5. | phage pe5, responsible for the conversion of type v antigen in shigella flexneri, has the ability to produce generalized transduction. the correlation between phage multiplicity and the number of transductants, the specific inhibitory activity of anti-pe5 serum, and the lack of transduction in pe5 resistant recipients, indicate the role of phage pe5 in generalized transduction. transduction of the r100-1 factor resulted in a non-transmissible tetracycline resistance segragation. the characterist ... | 1976 | 799898 |
| resistance to antibiotics of shigella strains isolated in somalia. | the resistance to antibiotics of 240 shigella strains isolated in somalia from 1973 to 1976 was studied. many strains, particularly those of shigella dysenteriae type 1, were found to be resistant to more than one drug. in view of their resistance to ampicillin, chloramphenicol, streptomycin, tetracycline, and sulfonamides, it is suggested that polymyxin b or m sulfate - which have proved to be effective in vivo - should be used for the treatment of clinically typical cases of bacillary dysenter ... | 1976 | 799953 |
| [researches on antibiotic-resistance in "shigella sonnei" and "flexneri" and in "salmonella typhimurium" (author's transl)]. | ampicillin (a), streptomycin (s), aminosidin (k), chloramphenical (c) and tetracycline (t) resistance was investigated in 130 s. typhi murium, 18 shigella flexneri and 13 shigella sonnei strains, recovered from enteritis cases in 1970-1973. all salmonella and 70% shigella strains (without any appreciable differences between sh. sonnei and flexneri) were found resistant and most multiresistant. a-s-k-c-t resistance was frequently found: in 48% of the salmonella and 12% of the shigella strains. as ... | 1976 | 800942 |
| gastro-enteritis in egypt, certain epidemiological aspects. | | 1976 | 801623 |
| scanning electron microscopic studies on the microstructure of s and r type colonies of salmonella and shigella groups. | | 1976 | 802350 |
| the effect of leukocyte hydrolases on bacteria. iii. bacteriolysis induced by extracts of different leukocyte populations and the inhibition of lysis by macromolecular substances. | the lysis of 14c-labeled bacteria by hydrolases of human and rabbit leukocytes was studied in vitro. while staphylococcus albus, streptococcus faecalis, and streptococcus mutans were highly susceptible to lysis, staphylococcus auresus was intermediate in its susecptibility to lysis by the leukocyte enzymes. group a streptococcus, listeria monocytogenes, shigella flexneri, escherichia coli, and mycobacterium smegmatis were very resistant to degradation by these enzymes. the lytic activity of leuk ... | 1975 | 804017 |
| trimethoprim-sulfamethoxazole in the treatment of gastrointestinal infections, including enteric fever and typhoid carriers. | forty-three patients suffering from typhoid fever, 11 from paratyphoid fever, six from bacillary dysentery caused by shigella flexneri, and nine carriers of salmonella typhi or s. paratyphi b, have been treated with trimethoprim-sulfamethoxazole compound. fifty-one of the 54 patients who had typhoid fever or paratyphoid fever responded satisfactorily to treatment. two patients with typhoid fever failed to respond and one died. in the patients with bacillary dysentery acute symptoms subsided rapi ... | 1975 | 805647 |
| substituted 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones. | a series of 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones has been prepared. a new synthesis of 4-alkyl-1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones involving the oxidative ring closure of 5-nitro-2-furaldehyde 2-(2-hydroxyethylalkyl)semicarbazones is described. the in vitro testing of the compounds against a variety of bacteria is reported. | 1975 | 807733 |
| divalent cation stimulation of the cell infectivity of shigella flexneri 2a. | | 1975 | 807763 |
| arylamidase activity of salmonella species. | arylamidase activity in cell extracts of sonically cell treated suspensions of 23 salmonella strains, including 12 strains of s. typhimurium, was investigated. all cultures hydrolyzed five of nine different neutral and basic substrates. activity against aspartyl-, cystyl- histidinyl-, and isoleucyl-beta-naphylamide was negligible. alanyl-beta-naphthylamide was the preferred substrate for the salmonella species; however, specific activities ranged widely. of several gram-negative organisms survey ... | 1975 | 808165 |
| transmissible drug resistance in shigella and salmonella isolated from pet monkeys and their owners. | during two dysentery outbreaks in primate pet owners, shigella and salmonella strains were isolated from the enteric flora. in both outbreaks the source of infection was traced to asymptomatic spider monkeys (ateles geoffroyi). the spider monkeys and their owners shed multiply drug-resistant shigella and salmonella serotypes. six of the nine bacterial strains isolated from the animals were multiply drug-resistant and capable of transferring antibiotic resistance patterns. | 1975 | 808621 |
| [antibacterial activity of a lysozyme-like enzyme from staphylococci]. | a lysozyme-like enzyme isolated from the culture broth of staph. aureus 712 presented in its native state a lipoproteid complex. the lytic and antibacterial spectrum of the enzyme was similar to that of the egg albumin enzyme. however, the lipoproteid complex was somewhat superior to the egg albumin complex in its activity against micrococcus lysodeikticus, a number of gramnegative bacteria and staphylococci. out of the organisms studied microccus lysodeikticus, sarcina and bac. subtilis proved ... | 1975 | 813563 |
| fluid and electrolyte transport in rhesus monkeys challenged intracecally with shigella flexneri 2a. | shigella flexneri 2a is an invasive enteric pathogen that may produce diarrhea when ingested by human beings and subhuman primates. we have previously shown that shigella diarrhea correlates with water and electrolyte transport abnormalities in the jejunum and colon. dysentery alone is associated only with colonic transport abnormalities. to define the relationship between invasion and inflammation of the colon and the occurrence of jejunal transport abnormalities, we studied water and electroly ... | 1976 | 823110 |
| glycerol dissimilation and its regulation in bacteria. | | 1976 | 825019 |
| irradiation of cells by single and double pulses of high intensity radiation: oxygen sensitization and diffusion kinetics. | the biological effects of ionizing radiation in living cells are the ultimate result of a long chain of events with the initial step being the local absorption of radiation. whereas such physical abosrption is probably over within 10(-16) s after dose delivery, the biological consequences of radiation do not manifest themselves until very much later times. between these two extremes of time, events occur relatively early at the molecular level which are undoubtedly critically related to the stil ... | 1976 | 826371 |
| recurrent urinary tract infection due to shigella flexneri--case report. | a case of urinary tract infection due to shigella flexneri is reported. the case presented suggests that in persistent and recurrent urinary tract infection in topical countries, investigations for organisms such as shigella flexneri should be considered. urinary tract infection due to shigella flexneri is unknown and as far as we known has not been reported in the literature. a case report is presented in whom recurrent urinary tract infection was due to shigella flexneri and was treated effect ... | 1976 | 826670 |
| [use of the neutralization test for mass population studies]. | the authors applied the antibody neutralization test (ant) for detection of causative agent of intestinal infections in feces of healthy population in turkmenia. some part of the material was studied in parallel with the aid of the ant and by the bacteriological method. as a result of comparison it appeared that in using the ant causative agents of intestinal infections were revealed much more frequently than by the bacteriological method; in this connection this serological method can be recomm ... | 1976 | 828825 |
| in vitro activity of cinoxacin, ampicillin, and chloramphenicol against shigella and nontyphoid salmonella. | the in vitro antibacterial activity of cinoxacin was compared with that of ampicillin and chloramphenicol against 26 strains of nontyphoid salmonella and 44 strains of shigella. cinoxacin was found to have a lower minimal inhibitory concentration than ampicillin and chloramphenicol against all salmonella and shigella sonnei strains. cinoxacin had minimal inhibitory concentrations similar to those of chloramphenicol but lower than those of ampicillin against shigella flexneri and s. boydii strain ... | 1977 | 856008 |
| drug evaluation of pyrantel pamoate against ancylostoma, toxocara, and toxascaris in eleven dogs. | eleven dogs dosed at approximately the recommended rate of 1.029 mg of pyrantel pamoate/kg of body weight were used. the efficacy against ancylostoma in the 11 dogs was 99% (av; min-max, 94-99%). in 4 dogs with both toxocara and ancylostoma, average efficacy against toxocara was 96%, and in 5 dogs with both toxoscaris and ancylostoma, efficacy against toxascaris was 93%. only 2 dogs of the 11 were infected with the 3 species; the average efficacy was 90%. there appeared to be no activity against ... | 1975 | 1057855 |
| multiple active forms of thrombin: binding to platelets and effects on platelet function. | the effect of various forms of thrombin on certain platelet functions has been investigated. partially purified bovine thrombin which is a mixture of multiple active forms of thrombin, was chromatographed to yield molecular species termed alpha-, beta-, and gamma-thrombin, each of which has varying degrees of fibrinogen clotting and esterase activities. a direct correlation was observed between the ability of the different forms of thrombin to clot fibrinogen and to influence platelet function. ... | 1976 | 1064039 |
| homologous inhibitors from potato tubers of serine endopeptidases and metallocarboxypeptidases. | a potent polypeptide inhibitor of chymotrypsin has been purified from russett burbank potatoes. the inhibitor has no effect on bovine carboxypeptidases a or b but exhibits homology with a carboxypeptidase inhibitor that is also present in potato tubers. the chymotrypsin inhibitor has a molecular weight of approximately 5400 as estimated by gel filtration, amino acid analysis, and titration with chymotrypsin. the polypeptide chain consists of 49 amino acid residues, of which six are half-cystine, ... | 1976 | 1064864 |
| [the nature of nuclear enlargement in urethane and isoprotenol-stimulated salivary glands (author's transl)]. | | 1975 | 1073694 |
| [the acute vestibular paralysis (author's transl)]. | acute vestibular paralysis may not be considered as a nosologic entity but as a syndrome. symptomatology (vertigo, spontaneous and provoked vestibular nystagmus, absence of cochlear signs) shows an uniform picture. the results of the caloric test as well as the nystagmic responses induced by galvanic stimulation and the development of central vestibular compensation however indicate that the site of the lesion is not only confined to the labyrinth but may also occur at the level of the periphera ... | 1975 | 1081389 |
| treatment of spontaneous leukemia in akr mice with chemotherapy, immunotherapy, or interferon. | akr mice are genetically destined to develop gross (rna) virus-induced lymphatic leukemia. leukemic akr mice treated with combination vincristine, cyclophosphamide (cytoxan), and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea sustained a 180% increase of life-span. combination chemotherapy plus immunization with neuraminidase-treated allogeneic (gross virus-induced) g2g leukemic cells intradermally resulted in 35% of animals surviving beyond 150 days without evidence of the disease ... | 1976 | 1082796 |
| lysozyme synthesis by established human and murine histiocytic lymphoma cell lines. | a human cell line established in culture from a histiocytic lymphoma patient synthesizes and secretes the monocyte-granulocyte specific enzyme lysozyme. 18 other human cell lines with characteristics of t-lymphocyte, b-lymphocyte, burkitt's lymphoma, non-burkitt's lymphoma, myeloma, and bone marrow epithelial cells were not associated with lysozyme. among murine cell lines, lysozyme was produced by (a) three histiocytic lymphoma or macrophage lines, which mediate antibody-dependent phagocytosis ... | 1976 | 1083890 |
| t-dependence of human b lymphocyte proliferative response to mitogens. | human peripheral blood and tonsil lymphocytes were fractionated on anti-ig-coated sephadex columns or by centrifugation after rosetting with native sheep erythrocytes. both methods allowed the recovery of b and t-enriched populations the purity of which was checked by fluorescein-labelled anti-ig serum, e and eac rosette formation, and heterologous antisera specific for b or t lymphocytes. the proliferative response of t cells to pha, con a, pwm, and als was not found different from that of unfr ... | 1976 | 1084330 |
| multiple h-2 linked immune response gene control of h-2 d-associated t-cell-mediated lympholysis to trinitrophenyl-modified autologous cells: ir-like genes mapping to the left of i-a and within the i region. | one of the more recent associations of the murine h-2 major histocompatibility complex (mhc) with immune function has been the finding that cytotoxic t-effector cells generated by sensitization with viral-infected (1-6), chemically modified (7-9), or weak transplantation antigen-associated (10,11) syngeneic cells can efficiently lyse target cells which express the same viral, chemical, or weak antigenic agent, and which share the h-2k and/or h-2d regions of the mhc with the responding and/or sti ... | 1976 | 1087329 |
| effects of thymectomy and antithymocyte serum on spontaneous regression of friend virus-induced erythroleukemia. | to evaluate the role of immune response in regression of leukemia, we studied the effect of immunosuppression on the spontaneous regression of a leukemia induced by a specific strain of friend murine leukemia virus complex (rfv). thymectomy of newborn but not adult outbred swiss mice markedly inhibited regression. the effect of antithymocyte serum (ats) on regression depended on the timing of ats treatment. regression was markedly inhibited in leukemic mice given ats just before the start of reg ... | 1976 | 1087346 |
| ampicillin-resistant strains of haemophilus influenzae type b in north carolina. | | 1976 | 1087376 |
| growth and death of diploid and transformed human fibroblasts. | three possible explanations are presented for the differences in growth potential between human diploid fibroblasts of finite life-span and permanent transformed lines: 1) only diploid cells have a molecular clock mechanism which counts cell divisions prior to senescence. two hypothetical examples of such mechanisms are described; however, the available evidence argues against a clock mechanism for aging in fibroblasts. 2) cells become committed with a given probability to a slow buildup in prot ... | 1975 | 1088944 |
| [mixed epidemic of typhoid fever and shigellosis]. | | 1975 | 1089349 |
| antimicrobial resistance of shigellae isolated in michigan. | patterns of antimicrobial resistance were studied for 213 strains of shigellae isolated in rural and urban areas of michigan by quantitative techniques: 66% of these organisms were resistant to ampicillin, tetracycline, cephalexin, or chloramphenicol or had multiple resistance to various combinations of these antibiotics. the incidence of resistant organisms was higher in the detroit-wayne county area, which is the most urban part of the state. nalidixic acid and oxolinic acid were noted to be q ... | 1975 | 1089819 |
| observations on the serologic changes in the recombinants in shigella flexneri serotype 4a. | studies on the antigenic composition of 84 diagnostic strains of s. flexneri serotype 4a and their lac+ recombinants from a cross with e. coli hfrc were carried out. considerable differentiation of agglutination reaction was found both in original material and in recombinants. an interesting group included recombinants which completely lost their capability to agglutinate with sera specific for type and group antigens and preserved only the capability to agglutinate in the polyvalent serum of s. ... | 1975 | 1090112 |
| pathophysiology of shigella diarrhea in the rhesus monkey: intestinal transport, morphological, and bacteriological studies. | in contrast to the "toxigenic diarrheas" caused by vibrio cholerae and escherichia coli, the site and mechanism of fluid loss in shigellosis are unknown. the occurrence of watery diarrhea in shigellosis suggests involvement of the small bowel. therefore, jejunal, ileal, and colonic water and electrolyte transport was studied in shigella flexneri 2a-infected monkeys. infected animals fell into three groups: dysentery alone, diarrhea alone, or diarrhea and dysentery. in controls, net water, sodium ... | 1975 | 1090480 |
| occurrence of the bacteriophage lambda receptor in some enterobacteriaceae. | in escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ... | 1975 | 1090748 |
| live versus killed bacterial vaccines. | | 1975 | 1090808 |
| phage conversion of shigella flexneri group antigens. | a temperate phage, designated sf6, has been isolated from shigella flexneri 3a. characterization of sf6 revealed that it possesses the capacity for converting the s. flexneri 3,4 group antigen complex to group factor 6. serological studies and chemical analysis of lipopolysaccharide from converted strains suggest that group factor 6 is a reflection of an acetylation of the preexisting 3,4 antigen complex. evidence is provided that the 3,4 group antigen complex functions, at least in part, as a c ... | 1975 | 1091548 |
| detection of a leukocytic endogenous mediator-like mediator of serum amino acid and zinc depression during various infectious illnesses. | serum samples from patients with many different kinds of infection were shown to contain a substance characteristic of leukocytic endogenous mediator. generalized bacterial infections produced more leukocytic endogenous mediator than did localized ones; viral infections produced very little. in typhoid fever, mediator concentrations increased before the onset of illness. | 1975 | 1091555 |
| [retroperitoneal, mediastinal and subcutaneous emphysema and bacillary dysentery]. | | 1975 | 1092028 |
| [sensitivity of different strains of e. coli and shigella to the inhibitory action of ploskirev's bactoagar]. | a study was made of the sensitivity of 190 strains of e. coli and 107 strains of shigellae of different serological types to the inhibitory action of ploskirev's bactoagar on the capacity of these bacteria to form colonies. the strains under study proved to be nonhomogenous in this respect: between different strains of e. coli there were revealed 10-, 100- and even 1000-fold differences by this property; the differences between shigellae strains were less marked--in over 90% of shigellae strains ... | 1975 | 1092090 |
| [genetic control of the ability of sh. flexneri to produce a lethal effect on macrophages. i. study of the possible extrachromosomal nature of the cyt+-determinant]. | it was shown that cyt+-determinant could not be eliminated when the sh. flexneri cultures were treated with ethidium bromide under the regimen providing the elimination of the f'lac-factor in a part of shigellae population. the cytotoxic sh. flexneri strains which acquired the r-factor transmitted the multiple drug resistance to the cyt minus -strain of sh. flexneri, but not the cyt+-properties. there was found no correlation between the cytoxicity of the sh. flexneri strains and their capacity ... | 1975 | 1092094 |
| [polyamines in species of microorganisms of the intestinal group]. | a study was made of polyamines (putrescine, spermidine and spermin) in various representatives of the enterobacteriaceae family--e. coli, sh, sonnei, sh. flexneri and s. typhi abdominalis. all the strains under study contained putrescine and spermidine, and many shigella and salmonella strains had spermin in addition. there were significant differences in the quantitative content of polyamines in the individual species. by the ratio of nitrogen of polyamine to phosphorus of nucleic acid it is po ... | 1975 | 1092098 |
| [microbial antagonism and its role in the development of infection (literature review)]. | | 1975 | 1092099 |
| [the role of the ability of sh. flexneri to synthesize pili of the common type in the development of dysenteric infections]. | hep-2 epithelial cells infected with isogenic sh. flexneri strains characterized by capacity to synthesize common pili (confirmed by electron microscopy) were studied. it was shown that although pili promoted an earlier adhesion of shigellae to the cells, they were not very significant for the penetration and intracellular development of dysentery bacilli in the epithelium. the use of bacteria labeled with 3h-glucose offers a possibility of an objective rapid and precise determination of the cap ... | 1975 | 1092108 |
| transfer of e1 and v colicinogenic factors to shigella flexneri. | from escherichia coli strains, cole1-ml and colv-k94 factors were transferred to a virulent shigella flexneri 2a strain at 1-2% frequency. s. flexneri colv+ and cole1+v+ produced col- segregants. the cole1 factor was stably incorporated into s. flexneri. the colv+ culture lost its virulence to the guinea pig eye. | 1975 | 1092133 |
| shigellosis at sea: an outbreak aboard a passenger cruise ship. | between june 23 and june 30, 1973, 90% of 650 passengers and at least 35% of 299 crew members experienced a diarrheal illness during a 7-day caribbean cruise aboard a passenger cruise liner. symptoms were consistent with shigellosis, and shigella flexneri 6, boyd 88 biotype, was isolated from rectal swabs taken from 8 to 35 ill passengers and 33 of 294 crew members. epidemiologic evidence incriminated the ship's water, including ice, as the probable vehicle of transmission, and elevated coliform ... | 1975 | 1092155 |
| [on flucloxacillin sensitivity determination by the disc method (author's transl)]. | | 1975 | 1092891 |
| undecaprenol phosphate, the endogenous acceptor of glucose from udpglucose in shigella flexneri. | | 1975 | 1093344 |
| superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1. | the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ... | 1975 | 1094073 |
| transmissible substrate-utilizing ability in enterobacteria. | three of 152 strains of escherichia coli transmitted their ability to utilize sucrose (sac+) to other strains by conjugation. the transfer factor of one of them and of a sac+ salmonella thompson strain was thermosensitive. the raffinose-utilizing ability of 27 of 163 e. coli strains was also transmissible. transmissible raffinose-utilizing ability was a feature of porcine enterpathogenic strains possessing the k88 antigen. the determinants controlling raffinose utilization (raf) and k88 antigen ... | 1975 | 1094091 |
| bacteremia in suckling rabbits after oral challenge with vibrio parahaemolyticus. | vibrio parahaemolyticus, a halophilic marine enteropathogen, produces diarrhea in man after ingestion of contaminated seafood. only strains capable of producing beta-hemolysis (kanagawa-positive strains) are enteropathogenic. yet the majority of marine isolants are nonhemolytic and kanagawa negative. studies were initiated in suckling rabbits in an attempt to elucidate pathogenetic mechanisms. fasting animals were infected orally with kanagawa-positive and kanagawa-negative strains of v. parahae ... | 1975 | 1095481 |
| role of immunoglobulins in protection against shigella-induced keratoconjunctives. | various immunoglobulin preparations were tested for their ability to protect guinea pig eyes from infection by a virulent strain of shigella flexneri. secretory immunoglobulin a was effective in delaying or preventing keratoconjunctivitis in eight guinea pigs when it was used to precoat the organism, and was also placed in the eye with the inoculum. neither immunoglobulin g nor immunoglobulin m gave any protection when used in the same way. protection by secretory immunoglobulin a appeared to be ... | 1975 | 1095483 |
| diarrhoea: a traveller's tale. | travellers' diarrhoea is a result of travelling overseas. proper diagnosis can only be made when a full microbiological investigation is carried. a case due to shigella flexneri is described. | 1975 | 1095981 |
| studies on the energetic metabolism of shigella flexneri times escherichia coli hybrids devoid of penetration ability i. glycolysis. | the aerobic and anaerobic (in presence of kcn) glycolysis is studied of avirulent hybrids of shigella flexneri according to the keratoconjunctivitis test of sereny with genetic characteristics lac-+kcp-minus devoid of penetration ability. it is established that lac-+kcp-minus hybrids which have lost their ability to penetrate the cells due to replacement of kcp-gene of the chromosome of donor strain e. coli k-12 p4 times, are characterized with a steep decrease of their glycolitic activity in bo ... | 1975 | 1096507 |
| shigellosis in a neonate: successful treatment with an oral elemental diet. | | 1975 | 1097146 |
| shigella strains associated with infantile diarrhea in the kaohsiung area. | in 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ... | 1975 | 1097211 |
| chronic vulvovaginitis in children due to shigella flexneri. | although previous reports have implicated shigella flexneri in resistant or chronic cases of vulvovaginitis in children, no authors have described the clinical findings of this condition. the report presents four cases of persistent vulvovaginitis in prepubertal indian girls from different reservation communities in arizona. s. flexneri was isolated in pure culture from the vaginal discharge of each patient. all four cases were characterized by a prolonged vaginitis with a bloody, purulent disc ... | 1975 | 1098002 |
| studies on the energetic metabolism of shigella flexneri and escherichia coli hybrids devoid of penetration ability. ii. oxygen uptake and dehydrogenase activity. | oxygen uptake and dehydrogenase activity are studied with lac+ kcpminus hybrids of shigella flexneri, being avirulent to the eyes of guinea pigs, because of having lost ability for penetration in epithelial cells. these strains were obtained by hybridization of the virulent strain shigella flexneri 222 5 a with the hfr strain escherichia coli k-12 p4x. it is established that lac+ kcp minus hybrids are characterized by significant decrease of respiratory activity. this decrease is outlined as a t ... | 1975 | 1098322 |
| [the anodic-moving thermolabile antigen (ata) of gram-negative bacteria: its occurrence in rough mutants of shigella flexneri and escherichia coli(author's transl)]. | the thermolabile antigen (ata) moving to the anode, discovered by us (9) and also described by larsson et al. (8), could be detected in ra-, rb-, re- and rd-mutants of sh. flexneri and, in smaller amounts, in rd- and re- mutants of e. coli o8:k27:h. so it proves to be different from kunin's common antigen (7). our results lead to the conclusion that ata is located in a more inner part of the bacterial cell wall and is fixed by noncovalent linkages. | 1975 | 1098323 |
| [prevalence of biochemical variants of shigella flexneri 6 in poland]. | | 1975 | 1101312 |
| epidemiologic investigation of an outbreak of shiga bacillus dysentery in an island population. | an epidemic of dysentery broke out in st. martin island during may through july 1973. the epidemic was caused by shigella dysenteriae type 1. the dysentery could not be controlled by conventional antibiotics and other antidysenteric drugs. the average attack rate was 32.9%. the age specific attack rate was highest in the age group 1-4 years (52.2%). the attack rates were higher in smaller families. the rates were not greatly different amongst people using different sources of water. the overall ... | 1975 | 1101385 |
| hemagglutination test in 150 children with diarrhoea and 100 normal children. | | 1975 | 1102449 |
| r-factors in urinary tract infection. | | 1975 | 1104976 |
| [comparative study of the preventive properties of sera obtained by immunization with shigella flexneri strains of varying degrees of virulence]. | | 1975 | 1106084 |
| [study of the sensitivity of shigella to ectericide]. | | 1975 | 1106086 |
| [intracellular parasitism of shigella in patients with dysentery]. | bioptic specimens of the mucosa of the distal portion of the colon in patients with dysentery, caused by flexner and sonne shigellas, were studied by luminescent-serological and electron-microscopy methods. in the cells with unchanged ultrastructure no shigellas were detected. intracellular localization of shigellas was observed only in cases of deep irreversible alterations in the ultrastructure of the cells. | 1975 | 1106366 |
| [morphologic characteristics of lysogenic phages with conversion activity in shigella flexneri]. | the morphology of three lysogenic bacteriophages which induce antigenic conversion in various shigella flexneri serotypes (ii and v type antigen and 7.8 group antigen) has been investigated. a quite different morphology appeared with respect to that of salmonella. | 1975 | 1107127 |
| [biochemical and genetic characteristics of enteropathogenic escherichia coli and shigella. v. the biological properties of auxotrophic mutants of shigella flexneri 2a and of escherichia coli serogroup 0124:k72]. | | 1975 | 1108515 |
| [genetic control of the capacity of sh. flexneri to exert a lethal effect on macrophages. ii. mapping of the cyt-determinant on the shigella chromosome]. | crossing experiments showed independence of the genetic determinants controlling the capacity of sh. flexneri to synthesize the primary s-specific side chains (antigen 3,4) and to produce a lethal action on macrophages cultivated in vitro. cytotoxicity was restored only in transmission to the r-strain of shigellae of the capacity to synthesize the antigenic factor 3,4 from the cyt+, but not from the cyt-- donor of sh. flexneri. the determinant responsible for the synthesis of cytotoxin designate ... | 1975 | 1108529 |
| [preparation and properties of some derivatives of methyl-6-amino-6,8 dideoxy-1-thio-d-erythro-alpha-d-galacto octopyranoside]. | | 1975 | 1108598 |
| changes in the biochemical properties of shigella flexneri la as a result of recombination with escherichia coli k12. | the fermentative properties of recombinants obtained after conjugation between e. coli k12 hfec and s. flexneri la lac phe mutant were investigated. the recombinants showed the antigenic structure of s. flexneri but their biochemical characteristics differed from the properties typical for this genus. the recombinants were found to acquire the ability to ferment several carbohydrates not degraded by the s. flexneri recipient strain. | 1975 | 1108604 |
| [prodigiosin in the overall therapy of dysentery and in the prevention of intrahospital viral respiratory infection in children]. | prodigiozan was tested in complex therapy of children with acute dysentery. comparison of clinical symptoms, specific immunogenesis and child sanation periods from shigella in the child groups treated (80) and non-treated (74) with prodigiozan showed that prodigiozan lowered the rate of intrahospital acute respiratory virus infection, provided more favourable dysentery progression, more tensed specific immunity and the patient clearance from shigella. | 1975 | 1108774 |
| subdividing of phage types of shigella flexneri by means of bacteriocins. | | 1975 | 1108842 |
| blockade by morphine of acetylcholine release from the caudate nucleus in the mid-pontine pretrigeminal cat. | | 1975 | 1111819 |
| free amino acids in human tonsillar tissue. | free amino acids in the tonsils of 20 individuals were measured column chromatographically. those always found in readily detectable amounts included o-phosphoserine, taurine, o-phosphoethanolamine, aspartic acid, hydroxyproline, threonine, serine, glutamic acid, proline, glycine, alanine, alpha-amino-n-butyric acid, valine, cystine, methionine, isoleucine, leucine, tyrosine, phenylalanine, ornithine, gamma-amino-butyric acid, lysine, histidine, and arginine. results were compared for three clin ... | 1975 | 1112054 |
| renal circulatory responses to general anaesthesia in the rabbit: studies using radioactive microspheres. | 1. total renal blood flow and its cortical distribution were measured by the radioactive microsphere technique in conscious rabbits and after anaethesia with pentobarbitone, chloralose-urethane or ether. 2. pentobarbitone anaesthesia caused a fall of 26% in total renal blood flow, of 26% in superficial cortical flow, and of 24% in deep cortical flow. sodium excretion rate fell by 33%. 3. chloralose-urethane anaesthesia caused no change in total or regional renal blood flow, or in sodium excretio ... | 1975 | 1112081 |
| endocrine responses to insulin hypoglycaemia in the young calf. | 1. variations in the output of glucocorticoids and catecholamines from the right adrenal gland, in response to insulin hypoglycaemia, have been investigated in calves 2-5 weeks after birth. these have been correlated with changes in the concentration of glucocorticoids and glucagon in arterial plasma. 2. moderate hypoglycaemia for a limited period (0-1 u. insulin/kg), elicited a prompt increase in steroid output from the adrenal gland followed by a significant rise in plasma glucagon concentrati ... | 1975 | 1133779 |
| significance of severity of coronary arterial stenosis: metabolic studies and correlation with hyperemic response. | | 1975 | 1134082 |
| essential dietary amino acids for growth of larvae of the yellow mealworm, tenebrio molitor l. | larvae of the yellow mealworm, tenebrio molitor l., have been used to evaluate nutritional quality of proteins and protein isolates. however, such investigations have been complicated by lack of knowledge of dietary requirements of the larvae. to determine essential dietary amino acids for growth of tenebrio molitor, single amino acids were deleted from the amino acid mixture of the diet. diets were maintained isonitrogenous with supplementary glycine and, in the case of deleted glycine, with gl ... | 1975 | 1142013 |
| proceedings: cell-wall composition of aerobic cutaneous "diphtherios" organisms. | | 1975 | 1142405 |
| aggregation states and catalytic properties of the multienzyme complex catalyzing the initial steps of pyrimidine biosynthesis in rat liver. | glutamine-dependent carbamoyl-phosphate synthetase was purified about 2100-fold from the cytosol of rat liver using 30% (v/v) dimethyl sulfoxide and 5% (w/v) glycerol as stabilizers. throughout the purification, aspartate transcarbamylase and dihydroorotase, the second and third enzymes of pyrimidine biosynthesis, were copurified with the synthetase. these three enzymes sedimented as a single peak with a sedimentation coefficient of 27 s in sucrose gradients containing the stabilizers, indicatin ... | 1975 | 1148171 |
| the detection of specific igm antibodies following infection with rubella virus. | a gel filtration technique using sephadex g-200 has been used for the detection of specific igm in sera from (a) 45 cases of clinical rubella in which diagnostic rises of rubella haemagglutination-inhibiting (hai) antibody could be demonstrated; (b) 70 cases with clinical evidence of rubella in which a rising titre could not be demonstrated because the first serum sample already had high titre hai antibodies; and (c) 100 patients in whom rubella was not suspected. the results indicate that the h ... | 1975 | 1150889 |
| pentobarbital pharmacokinetics in the normal and in the hepatectomized rat. | the pharmacokinetics of pentobarbital, a barbiturate metabolized by the liver, was compared in normal and in hepatectomized rats. the blood concentration time curve following a single intravenous injection of pentobarbital was fitted to a two-compartment open model. both the volume of the central compartment and the elimination rate constant were significantly reduced in hepatectomized rats. it is concluded that the liver plays a role both in the metabolism and the distribution of pentobarbital. | 1975 | 1151743 |
| a study of absorption of compounds from the rat biliary tree by retrograde intrabiliary injection (rii). | absorption of compounds from the biliary tree of rats was studied by a retrograde intrabiliary injection (rii) technique. after rii of a number of compounds in volumes that exceeded the maximum distended capacity of the biliary tree, only that volume of rii solution which corresponded to biliary tree capacity remained therein. furthermore, this latter portion of rii solution was absorbed by a first-order process when the duration of bile duct cannula occlusion was extended. thus, the present stu ... | 1975 | 1151745 |
| effects of sodium acetylsalicylate on body temperature of monkeys under heat exposure. | exposure of taiwan monkeys to 38 degrees c ambient temperature caused: a) raised body temperature, b) restlessness and struggling, c) increased evaporative heat loss and d) increase in tail skin temperature. after the administration of sodium acetylsalicylate, 100 to 250 mg/kg intraperitoneally or 4 to 15 mg intracerebroventricularly (third ventricle) the same heat load caused: a) less increase in body temperature, b) no restlessness or struggling, c) an initially higher rate of evaporative heat ... | 1975 | 1151748 |
| proceedings: effects of histamine, 2-methylhistamine and 4-methylhistamine on blood pressure and vascular resistance in the cat. | | 1975 | 1151865 |
| dietary fats and properties of endoplasmic reticulum: i. dietary lipid induced changes in composition of microsomal membranes in liver and gastroduodenal mucosa of rat. | rats were fed for four weeks with different lipid diets to determine the effects on the endoplasmic reticulum membranes of the liver and on the postmitochondrial supernatant fraction of the gastroduodenal mucosa. the diets contained cholesterol, cacao butter, olive oil, and these in combination. the results showed that dietary lipids were able to modify the composition of the hepatic endoplasmic reticulum and, to a lesser extent, that of postmitochondrial fraction of gastroduodenal mucosa. cacao ... | 1975 | 1160521 |
| structural similarity of the membrane envelopes of rhizobial bacteroids and the host plasma membrane as revealed by freeze-fracturing. | the freeze-fracture technique was used to study the host plasma membrane and the membrane envelope of bacteroids in rhizobial root nodules of three host-rhizobium combinations. in all three combinations studied, the membrane envelopes of bacteroids are structurally similar to their host plasma membrane. however, the membrane appears to be reversed, because the number and arrangement of particles in the outer fractured face (face a, concave) and in the inner fractured face (face b, convex) of the ... | 1975 | 1168633 |
| transport and storage of serotonin by thrombin-treated platelets. | repeated thrombin treatment of washed platelets prepared from rabbits can decrease the serotonin content of the platelets by about 80%. when these platelets are deaggregated they reaccumulate serotonin but their storage capacity for serotonin is reduced by about 60%. if thrombin-pretreated platelets are allowed to equilibrate with a high concentration of serotonin (123 mu m), they release a smaller percentage of their total serotonin upon further thrombin treatment, in comparison with the percen ... | 1975 | 1168649 |
| [dynamics of cell divisions and involutions of immunocompetent cells of the axillary lymp nodes in conditioned and non-conditioned immunity in rats]. | | 1975 | 1170630 |