Publications

chemical constituents from the flowering buds of bauhinia tomentosa linn (fbbt).	isolation and characterisation of compounds, 1-(2'-hydroxy-4'-methoxyphenyl)-3-(4″-methoxyphenyl)-2-hydroxypropane-1,3-dione (1), 5-hydroxyflavone (2), 3,5,7,3',4'-pentahydroxyflavone (3), 3,5,7,2',4'-pentahydroxyflavone (4) and 5,7,3',4'-tetrahydroxyflavone-3-o-rhamnoside (5) are reported from the air dried flowering buds of bauhinia tomentosa linn. their structures are determined on the basis of extensive chemical and spectral evidences. compound (1) is reported for the first time from the pla ...	2016	26745556
nephroprotective effect of bauhinia tomentosa linn against cisplatin-induced renal damage.	cisplatin (cp) is an important chemotherapeutic drug used for the treatment of a wide variety of solid tumors. however, clinical use of cp has been limited due to its adverse effect of nephrotoxicity. in the present study, we evaluate the nephroprotective effect of bauhinia tomentosa against cp-induced renal damage in rats. administration of methonolic extract of b. tomentosa (250 mg/kg b.w.) results in a significant increase in antioxidant enzymes including superoxide dismutase (sod), glutathio ...	2016	27481488
anti-tumor and chemoprotective effect of bauhinia tomentosa by regulating growth factors and inflammatory mediators.	cancer is a leading cause of death worldwide. due to the toxic side effects of the commonly used chemotherapeutic drug cyclophosphamide (ctx), the use of herbal medicines with fewer side effects but having potential use as inducing anti-cancer outcomes in situ has become increasingly popular. the present study sought to investigate the effects of a methanolic extract of bauhinia tomentosa against dalton's ascites lymphoma (dal) induced ascites as well as solid tumors in balb/c mice. specifically ...	2015	26745048
protective effect of bauhinia tomentosa on acetic acid induced ulcerative colitis by regulating antioxidant and inflammatory mediators.	inflammatory bowel diseases (ibd), including crohn's disease and ulcerative colitis (uc), are life-long and recurrent disorders of the gastrointestinal tract with unknown etiology. the present study is designed to evaluate the ameliorative effect of bauhinia tomentosa during ulcerative colitis (uc). three groups of animals (n=6) were treated with b. tomentosa (5, 10, 20 mg/kg b.wt respectively) for 5 consecutive days before induction of uc. uc was induced by intracolonic injection of 3% acetic a ...	2013	23538025
assessment of the potentiality of tdz on multiple shoot induction in bauhinia tomentosa l., a woody legume.	an efficient and reproducible protocol for in vitro multiplication of bauhinia tomentosa l. was developed. multiple shoots were regenerated from cotyledonary node and stem nodal segments excised from in vitro raised seedlings on murashige and skoog (ms) medium supplemented with different concentrations (0.1, 0.3, 0.5, 0.8 and 1.0 μm) of thidiazuron (tdz). the maximum response (62.6%) was recorded on ms medium amended with 0.8 μm tdz. a long exposure to tdz for 8 weeks showed abnormalities such a ...	2012	23134604
glucose lowering effect of aqueous extract of bauhinia tomentosa l. on alloxan induced type 2 diabetes mellitus in wistar albino rats.	the study was designed to evaluate the anti-diabetic effect of aqueous extract of bauhinia tomentosa l. leaf on alloxan induced wistar albino rats. diabetes was induced in albino rat models with alloxan monohydrate (150mg/kg body weight). aqueous leaf extract of bauhinia tomentosa at the dose of 300 mg/kg was orally administered once a day for 30 days to the diabetic animals. in this study, glycemic parameters, lipid parameters and serum enzymes were reduced whereas the level of high-density lip ...	2011	24826019
antimicrobial activity of bauhinia tomentosa and bauhinia vahlii roots.	the hexane, ethylacetate and methanol extracts from bauhinia tomentosa and bauhinia vahlii roots were tested for their antimicrobial activity against gram-positive bacteria (four strains), gram-negative bacteria (three strains) and three fungi strains using microdilution methods, for the determination of minimal inhibition concentration (mic) and the minimal microbicidal concentration (mmc). the mic values of hexane extracts of b. tomentosa and b. vahlii roots were more than 250 µg/ml. the mic v ...	2010	20931080
bauhinia tomentosa stimulates the immune system and scavenges free radical generation in vitro.	a methanolic extract of bauhinia tomentosa was studied for its immunomodulatory, antioxidant, and anti-inflammatory activity in balb/c mice. intraperitoneal administration of the extract significantly increased the total leukocyte account (10075 +/- 542 cells/cm2) on the 18th day, bone marrow cellularity (93.1 x 10(5) +/- 3.35 cells/femur), and alpha-esterase positive cells (1332 +/- 32 cells/4000 bone marrow cells) when compared with untreated control mice. the weights of lymphoid organs, such ...	2010	20853598