Publications

anti-inflammatory effects of the methanol extract of sedum telephium ssp. maximum in lipopolysaccharide- stimulated rat peritoneal macrophages.	sedum telephium ssp. maximum is a medicinal plant that possesses anti-inflammatory, analgesic and keratolytic properties. we investigated the anti-inflammatory activity of its methanolic extract (stme) in rat peritoneal macrophages (mphis) stimulated with lipopolysaccharide from salmonella enteritidis. after stimulation with 10 microg/ml of lps, mphis were coincubated with different doses of stme (8, 16 and 32 microg/ml) or rpmi medium alone using different times of incubation. stme reduced leve ...	2008	18818510
sedum telephium l. polysaccharide content affects mrc5 cell adhesion to laminin and fibronectin.	in traditional medicine the fresh leaves and juice of sedum telephium l. are used as wound-healing promoters. cell adhesion represents a primary event in wound repair and in tissue homeostasis, and therefore we have investigated the effect of sedum juice and its main fractions, polysaccharides and flavonols, on human fibroblast (mrc5) adhesion to fibronectin and laminin. our findings revealed that total sedum juice strongly inhibited cell adhesion to laminin and fibronectin (ec50 1.03+/-0.12 mg ...	2000	10864148
in-vitro antioxidant and in-vivo photoprotective effect of three lyophilized extracts of sedum telephium l. leaves.	sedum telephium l. is a medicinal plant used in antiquity to cure many types of inflammatory skin diseases. the leaves (without the external cuticle), are used to promote healing and reduce skin inflammation and pain, and contain various components. we found two major components: flavonol glycosides and polysaccharides, with molecular weight between 13,000 and 13,500 da. we evaluated the in-vitro antioxidant and in-vivo skin photoprotective effects of three lyophilized extracts obtained from the ...	2000	11092573
anti-inflammatory and immunologically active polysaccharides of sedum telephium.	two major polysaccharides, rhamnogalacturonans with mean m(r)s of 13,500 and 13,000, were isolated from dried leaves of sedum telephium by column chromatography on deae-sepharose cl-6b and gel filtration on fractogel tsk hw-50 (s) and sephacryl 200 hr. the structures were determined mainly by nmr spectroscopy, methylation analysis and gc-ms of the partially methylated alditol acetates, carboxyl reduction and by analysis of acidic and enzymatic degradation products. both polysaccharides exert an ...	1993	7764285
electrophoretic analysis of protoplast, vacuole, and tonoplast vesicle proteins in crassulacean acid metabolism plants.	protoplasts and vacuoles were isolated and purified in large numbers from the cam plants ananas comosus (pineapple) and sedum telephium for protein characterization. vacuoles were further fractionated to yield a tonoplast vesicle preparation. polypeptides of protoplasts, vacuoles, and tonoplast vesicles were compared to whole leaf polypeptides from both plants by one-dimensional sodium dodecylsulfate-polyacrylamide gel electrophoresis. approximately 100 vacuole polypeptides could be resolved of ...	1986	16665166
maintenance carbon cycle in crassulacean acid metabolism plant leaves : source and compartmentation of carbon for nocturnal malate synthesis.	the reciprocal relationship between diurnal changes in organic acid and storage carbohydrate was examined in the leaves of three crassulacean acid metabolism plants. it was found that depletion of leaf hexoses at night was sufficient to account quantitatively for increase in malate in ananas comosus but not in sedum telephium or kalanchoë daigremontiana. fructose and to a lesser extent glucose underwent the largest changes. glucose levels in s. telephium leaves oscillated diurnally but were not ...	1985	16664005
[antiviral activity of representatives of the family crassulaceae].	the antiviral properties of the juice of 11 species of the orpine family were studied. 8 of them belonged to the genera kalanchoe, i. e. kalanchoe diagremontiona r. hamet, k. pinnata (zam.) persoon, k. peteri werd., k. prolifera (bovie) r. hamet, k. marnierriana (mann. et boit) jacobs; k. blossfeldiana v. poelln, k. beharensis drake del gastillo, k. waldheimii r. hamet et perr and 3 belonged to the sedum genera, i. e. sedum telephium l., s. spectabile boreau, s. acre l. a high virus neutralizing ...	1981	7198890
the rapid isolation of vacuoles from leaves of crassulacean acid metabolism plants.	a technique is presented for the isolation of vacuoles from sedum telephium l. leaves. leaf material is digested enzymically to produce protoplasts rapidly which are partially lysed by gentle osmotic shock and the inclusion of 5 millimolar ethyleneglycol-bis (beta-aminoethyl ether)n,n'-tetraacetic acid in the wash medium. vacuoles are isolated from the partially lysed protoplasts by brief centrifugation on a three-step ficoll-400 gradient consisting of 5, 10, and 15% (w/v) ficoll-400. a majority ...	1980	16661440