Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| highly efficient transformation system for malassezia furfur and malassezia pachydermatis using agrobacterium tumefaciens-mediated transformation. | malassezia spp. are part of the normal human and animal mycobiota but are also associated with a variety of dermatological diseases. the absence of a transformation system hampered studies to reveal mechanisms underlying the switch from the non-pathogenic to pathogenic life style. here we describe, a highly efficient agrobacterium-mediated genetic transformation system for malassezia furfur and m. pachydermatis. a binary t-dna vector with the hygromycin b phosphotransferase (hpt) selection marke ... | 2017 | 28064034 |
| biofilm, adherence, and hydrophobicity as virulence factors in malassezia furfur. | malassezia species are natural inhabitants of the healthy skin. however, under certain conditions, they may cause or exacerbate several skin diseases. the ability of this fungus to colonize or infect is determined by complex interactions between the fungal cell and its virulence factors. this study aims to evaluate "in vitro" the hydrophobicity levels, the adherence on a plastic surface and the biofilm formation of 16 clinical isolates of malassezia furfur. cellular surface hydrophobicity (csh) ... | 2017 | 28340187 |
| mycology of cutaneous fungal infections in ambajogai: a rural area. | two hundred and eithteen cases of fungal skin infections were studied. tinea cruris was most common (34.4%), followed by tinea corporis (23.8%) znd tinea pedis (21.6%). tinea versicolor (8.7%) tinea manum (4.6%) tinea ungaium (3.7%) and tinea capitis (3.2%) were also seen. the male: female ratio was 4:1. the total isolates were 117. trichophyton rubrum was the most common isolate (35%). closely followed by epidermophyton floccosum (31.6%). trichphyton mentagrophytes (17.9%), malassezia furfur (1 ... | 2017 | 28211405 |
| [in vitro antifungal activity of azoles and amphotericin b against malassezia furfur by the clsi m27-a3 microdilution and etest(®) methods]. | malassezia furfur is a human skin commensal yeast that can cause skin and opportunistic systemic infections. given its lipid dependant status, the reference methods established by the clinical and laboratory standards institute (clsi) to evaluate antifungal susceptibility in yeasts are not applicable. | 2017 | 28214276 |
| ketoconazole inhibits malassezia furfur morphogenesis in vitro under filamentation optimized conditions. | malassezia furfur, a constituent of the normal human skin flora, is an etiological agent of pityriasis versicolor, which represents one of the most common human skin diseases. under certain conditions, both exogenous and endogenous, the fungus can transition from a yeast form to a pathogenic mycelial form. to develop a standardized medium for reproducible production of the mycelial form of m. furfur to develop and optimize susceptibility testing for this pathogen, we examined and characterized v ... | 2017 | 27885419 |
| performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identifying clinical malassezia isolates. | the genus malassezia comprises commensal yeasts on human skin. these yeasts are involved in superficial infections but are also isolated in deeper infections, such as fungemia, particularly in certain at-risk patients, such as neonates or patients with parenteral nutrition catheters. very little is known about malassezia epidemiology and virulence. this is due mainly to the difficulty of distinguishing species. currently, species identification is based on morphological and biochemical character ... | 2017 | 27795342 |
| the role of drug efflux pumps in malassezia pachydermatis and malassezia furfur defence against azoles. | this study aims to evaluate the effect of efflux pump modulators (epms) on the minimal inhibitory concentration (mic) of fluconazole (flz) and voriconazole (vor) in malassezia furfur and malassezia pachydermatis. the in vitro efficacy of azoles, in combination with epms (ie haloperidol-hal, promethazine-ptz and cyclosporine a-cys), against 21 m. furfur from bloodstream infection patients and 14 m. pachydermatis from the skin of dogs with dermatitis, was assessed using a broth microdilution chequ ... | 2017 | 27774659 |
| anti-dermatophyte and anti-malassezia activity of extracts rich in polymeric flavan-3-ols obtained from vitis vinifera seeds. | several human skin diseases are associated with fungi as dermatophytes and malassezia. skin mycoses are increasing and new alternatives to conventional treatments with improved efficacy and/or safety profiles are desirable. for the first time, the anti-dermatophytes and the anti-malassezia activities of vitis vinifera seed extracts obtained from different table and wine cultivars have been evaluated. geometric minimal inhibitory concentration ranged from 20 to 97 µg/ml for dermatophytes and from ... | 2017 | 27739110 |
| clinicomycological profile of pityriasis versicolor in assam. | geographical variation in the distribution of malassezia species associated with pityriasis versicolor (pv) has led to the necessity of studying epidemiological, mycological, and clinical characteristics of pv. | 2017 | 27166032 |
| terbinafin 1% cream and ketoconazole 2% cream in the treatment of pityriasis versicolor: a randomized comparative clinical trial. | to make a comparison between terbinafine 1% cream and ketoconazole 2% cream in the treatment of pityriasis versicolor. | 2017 | 25674122 |
| nipple hyperkeratosis due to malassezia furfur showing excellent response to itraconazole. | 2017 | 26120192 | |
| silver nanoparticles from pilimelia columellifera subsp. pallida sl19 strain demonstrated antifungal activity against fungi causing superficial mycoses. | in this study, we present the in vitro antifungal activity of silver nanoparticles (agnps) synthesized from acidophilic actinobacterium pilimelia columellifera subsp. pallida sl19 strain, alone and in combination with antibiotics viz., amphotericin b, fluconazole, and ketoconazole against pathogenic fungi, namely candida albicans, malassezia furfur, and trichophyton erinacei. the minimum inhibitory concentration (mic) and minimum biocidal concentration (mbc) of agnps against test fungi were eval ... | 2017 | 28670763 |
| [psoriasis capitis and seborrhoic eczema of scalp diseases]. | the scalp may be affected by various diseases with equally varying manifestations. erythema and scaling is often accompanied by agonizing itch. scalp psoriasis and seborrheic eczema represent the most frequent diseases, which can be differentiated into classical cases; however, overlap and similarities are seen. sharply demarcated erythematosquamous plaques across the natural hairline in psoriasis are opposed to blurred dark-red erythema and yellowish, greasy scales in seborrheic eczema. whereas ... | 2017 | 28567508 |
| size- and shape-dependent clinical and mycological efficacy of silver nanoparticles on dandruff. | dandruff is a prominent scalp problem caused by the growth of fungus malassezia furfur, potentially cascading into dermal inflammation, itching, and tissue damage. the present work outlines a detailed analysis of the treatment of scalp infection using silver nanomaterials (ag nms), and focuses on biocidal activity owing to manipulation of size, shape, and structure. monodisperse silver spherical nanoparticles (nps) and nanorods (nrs) were synthesized by chemical routes that were characterized us ... | 2016 | 26792991 |
| malassezia species in healthy skin and in dermatological conditions. | the genus malassezia comprises lipophilic species, the natural habitat of which is the skin of humans and other warm-blooded animals. however, these species have been associated with a diversity of dermatological disorders and even systemic infections. pityriasis versicolor is the only cutaneous disease etiologically connected to malassezia yeasts. in the other dermatoses, such as malassezia folliculitis, seborrheic dermatitis, atopic dermatitis, and psoriasis, these yeasts have been suggested t ... | 2016 | 26710919 |
| in vitro antifungal activity of extracts obtained from hypericum perforatum adventitious roots cultured in a mist bioreactor against planktonic cells and biofilm of malassezia furfur. | xanthone-rich extracts from hypericum perforatum root cultures grown in a mist bioreactor as antifungal agents against malassezia furfur. extracts of hypericum perforatum roots grown in a bioreactor showed activity against planktonic cells and biofilm of malassezia furfur. dried biomass, obtained from roots grown under controlled conditions in a rootec mist bioreactor, has been extracted with solvents of increasing polarity (i.e. chloroform, ethyl acetate and methanol). the methanolic fraction w ... | 2016 | 26166743 |
| anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using coriandrum sativum leaf extract. | in this present investigation, agnps were green synthesised using coriandrum sativum leaf extract. the physicochemical properties of agnps were characterised using uv-visible spectrophotometer, field emission scanning microscopy/energy dispersive x-ray (fesem/edx), fourier transformed infrared spectroscopy (ft-ir), x-ray diffraction (xrd) and brunauer-emmett-teller (bet) analysis. further, in vitro anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised agnps were assessed ... | 2016 | 27541567 |
| malassezia pneumonia: a rare complication of parenteral nutrition therapy. | malassezia species (formerly known as pityrosporum) are part of normal human skin flora and have been associated with benign dermatologic conditions, such as seborrheic dermatitis and tinea versicolor. in rare cases, however, malassezia has been associated with systemic disease in immunocompromised patients and infants in the neonatal intensive care unit. malassezia species require long-chain fatty acids for growth and therefore have a known predilection for individuals receiving lipid containin ... | 2016 | 26150410 |
| confluent and reticulated papillomatosis: diagnostic and treatment challenges. | confluent and reticulated papillomatosis (crp) of gougerot and carteaud was first typified in 1927. with the help of electron microscopy, it has been elucidated that crp arises due to aberrant keratinization. however, till date, there is no clear consensus on the etiologic trigger for crp. prevailing postulates include a bacterial trigger by dietzia papillomatosis (type strain n 1280(t)), an exaggerated cutaneous response to malassezia furfur, an endocrine basis stemming from insulin resistance, ... | 2016 | 27601929 |
| acidophilic actinobacteria synthesised silver nanoparticles showed remarkable activity against fungi-causing superficial mycoses in humans. | superficial mycoses are limited to the most external part of the skin and hair and caused by malassezia sp., trichophyton sp. and candida sp. we report extracellular biosynthesis of silver nanoparticles (agnps) by acidophilic actinobacteria (sf23, c9) and its in vitro antifungal activity against fungi-causing superficial mycoses. the phylogenetic analysis based on the 16s rrna gene sequence of strains sf23 and c9 showed that they are most closely related to pilimelia columellifera subsp. pallida ... | 2016 | 26671603 |
| low utility of pediatric isolator blood culture system for detection of fungemia in children: a 10-year review. | the use of the wampole isolator 1.5-ml pediatric blood culture tube for the detection of fungemia in children was assessed by a 10-year retrospective review at two pediatric hospitals, the hospital for sick children in toronto, canada, and the children's medical center of dallas, texas. over this period, a total of 9,442 pediatric isolator specimens were processed, with yeast or yeast-like organisms recovered in 297 (3.1%) of the specimens (151 [1.6%] unique clinical episodes) and filamentous or ... | 2016 | 27307462 |
| gene function analysis in the ubiquitous human commensal and pathogen malassezia genus. | the genus malassezia includes 14 species that are found on the skin of humans and animals and are associated with a number of diseases. recent genome sequencing projects have defined the gene content of all 14 species; however, to date, genetic manipulation has not been possible for any species within this genus. here, we develop and then optimize molecular tools for the transformation of malassezia furfur and malassezia sympodialis using agrobacterium tumefaciens delivery of transfer dna (t-dna ... | 2016 | 27899504 |
| investigations of kanuka and manuka essential oils for in vitro treatment of disease and cellular inflammation caused by infectious microorganisms. | diseases caused by infectious and inflammatory microorganisms are among the most common and most severe nosocomial diseases worldwide. therefore, developing effective agents for treating these illnesses is critical. in this study, essential oils from two tea tree species, kanuka (kunzea ericoides) and manuka (leptospermum scoparium), were evaluated for use in treating diseases and inflammation caused by microorganism infection. | 2016 | 24582465 |
| pityriazepin and other potent ahr ligands isolated from malassezia furfur yeast. | malassezia furfur yeast strains isolated from diseased human skin preferentially biosynthesize indole alkaloids which can be detected in the human skin and are highly potent activators of the aryl hydrocarbon receptor (ahr) and ahr-dependent gene expression. chemical analysis of an etoac extract of a m. furfur strain obtained from diseased human skin and grown on l-tryptophan agar revealed several known ahr active tryptophan metabolites along with a previously unidentified compound, pityriazepin ... | 2015 | 25721496 |
| azole susceptibility of malassezia pachydermatis and malassezia furfur and tentative epidemiological cut-off values. | this study aims to determine the minimal inhibitory concentration (mic) distribution and the epidemiological cut-off values (ecvs) of malassezia pachydermatis and malassezia furfur isolates for fluconazole (flz), itraconazole (itz), posaconazole (pos), and voriconazole (vor). a total of 62 m. pachydermatis strains from dogs with dermatitis and 78 m. furfur strains from humans with bloodstream infections (bsi) were tested by a modified broth microdilution clinical and laboratory standards institu ... | 2015 | 26162472 |
| differential expression of extracellular lipase and protease activities of mycelial and yeast forms in malassezia furfur. | malassezia furfur is a dimorphic yeast that is part of the human skin microflora. this fungus is a pathogen of a certain skin diseases, such as pityriasis versicolor, and in rare cases causes systemic infection in neonates. however, the role of dimorphism in the pathogenicity remains unclear. a modified induction medium (im) was successfully able to induce mycelial growth of m. furfur under both solid and liquid condition. filamentous elements with branching hyphae were observed when cultured in ... | 2015 | 26173769 |
| atopic dermatitis from adolescence to adulthood in the toacs cohort: prevalence, persistence and comorbidities. | while much is known about childhood atopic dermatitis, little is known about persistence of atopic dermatitis into adult life. we report, to our knowledge for the first time, the clinical course of atopic dermatitis in an unselected cohort of adolescents followed into adulthood. | 2015 | 25832131 |
| in vitro activity of two amphotericin b formulations against malassezia furfur strains recovered from patients with bloodstream infections. | although guidelines for the treatment of malassezia furfur fungemia are not yet defined, clinical data suggest that amphotericin b (amb) is effective for treating systemic infections. in the absence of clinical breakpoints for malassezia yeasts, epidemiological cut-off values (ecvs) are useful to discriminate between isolates with and without drug resistance. this study aimed to compare the distribution of minimal inhibitory concentration (mic) and the ecvs for amb of both deoxycholate (d-amb) a ... | 2015 | 25631480 |
| detection and identification of malassezia species in domestic animals and aquatic birds by pcr-rflp. | the present study aimed at detection and species-level identification of the malassezia yeasts in domestic animals and aquatic birds by polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp). samples were collected using tape strips and swabs from 471 animals including 97 horses, 102 cattle, 105 sheep, 20 camels, 60 dogs, 30 cats, 1 hamster, 1 squirrel, 50 aquatic birds and 5 turkeys. tape-strip samples were examined by direct microscopy. all samples were inoculated on mod ... | 2015 | 27175148 |
| antifungal effect of tons504-photodynamic therapy on malassezia furfur. | numerous reports indicate therapeutic efficacy of photodynamic therapy (pdt) against skin tumors, acne and for skin rejuvenation. however, few reports exist regarding its efficacy for fungal skin diseases. in order to determine the antifungal effect, pdt was applied on malassezia furfur. m. furfur was cultured in the presence of a novel cationic photosensitizer, tons504, and was irradiated with a 670-nm diode laser. tons504-pdt showed a significant antifungal effect against m. furfur. the effect ... | 2014 | 25226792 |
| in vitro antifungal susceptibility of malassezia furfur from bloodstream infections. | fungaemia caused by malassezia spp. in hospitalized patients requires prompt and appropriate therapy, but standard methods for the definition of the in vitro antifungal susceptibility have not been established yet. in this study, the in vitro susceptibility of malassezia furfur from bloodstream infections (bsis) to amphotericin b (amb), fluconazole (flc), itraconazole (itc), posaconazole (pos) and voriconazole (vrc) was assessed using the broth microdilution (bmd) method of the clinical and labo ... | 2014 | 25168965 |
| skin colonization by malassezia spp. in hospitalized neonates and infants in a tertiary care centre in north india. | malassezia, a skin colonizer, is associated with multiple skin disorders in adults, and cephalic pustulosis and folliculitis in children. it can cause fungemia in infants and neonates. the time and pattern of colonization, risk factors associated with colonization and causing fungemia in children, are not well understood. the prospective cohort study was conducted to determine the rate of malassezia species colonization and associated factors in hospitalized neonates and infants. consecutive 50 ... | 2014 | 25037485 |
| antifungal susceptibility of malassezia furfur, malassezia sympodialis, and malassezia globosa to azole drugs and amphotericin b evaluated using a broth microdilution method. | we studied the in vitro activity of fluconazole (fcz), ketoconazole (ktz), miconazole (mcz), voriconazole (vcz), itraconazole (itz) and amphotericin b (amb) against the three major pathogenic malassezia species, m. globosa, m. sympodialis, and m. furfur. antifungal susceptibilities were determined using the broth microdilution method in accordance with clinical and laboratory standards institute reference document m27-a3. to support lipid-dependent yeast development, glucose, peptone, ox bile, m ... | 2014 | 24965946 |
| bloodstream infections by malassezia and candida species in critical care patients. | despite being considered an emerging yeast related to immunocompromised individuals, severe infections by malassezia furfur have not been evaluated. during a one-year survey on yeasts fungemia, 290 neonatal and 17 pediatric patients with intravascular catheters, lipid parenteral nutrition, prolonged ward stay, and surgery were enrolled. in addition, the origin of the infection was investigated by swabbing hand skin of patients, parents, and healthcare workers and medical devices. all biological ... | 2014 | 24576998 |
| tacrolimus does not alter the production of several cytokines and antimicrobial peptide in malassezia furfur-infected-keratinocytes. | topical immunosuppressant therapy is widely used in the treatment of inflammatory skin diseases, such as atopic dermatitis and psoriasis. besides its beneficial therapeutic effects, application of topical anti-inflammatory drugs may render the epidermis more vulnerable to invading pathogens by suppressing innate immune responses in keratinocytes (kcs). cytokines, chemokines and antimicrobial peptides (amps) produced by epithelial cells enable them to participate in innate and acquired immune res ... | 2014 | 24512536 |
| antifungal activity and pore-forming mechanism of astacidin 1 against candida albicans. | in a previous report, a novel antibacterial peptide astacidin 1 (fkvqnqhgqvvkifhh) was isolated from hemocyanin of the freshwater crayfish pacifastacus leniusculus. in this study, the antifungal activity and mechanism of astacidin 1 were evaluated. astacidin 1 exhibited antifungal activity against candida albicans, trichosporon beigelii, malassezia furfur, and trichophyton rubrum. also, astacidin 1 had fungal cell selectivity in human erythrocytes without causing hemolysis. to understand the ant ... | 2014 | 24955933 |
| in vitro anti-malassezia activity and potential use in anti-dandruff formulation of asparagus racemosus. | malassezia species are frequently associated with dandruff and seborrhoeic dermatitis. the study was conducted to evaluate anti-fungal activities of the extracts obtained from the roots of asparagus racemosus willd against malassezia furfur and m. globosa. | 2014 | 24117781 |
| escmid and ecmm joint clinical guidelines for the diagnosis and management of rare invasive yeast infections. | the mortality associated with invasive fungal infections remains high with that involving rare yeast pathogens other than candida being no exception. this is in part due to the severe underlying conditions typically predisposing patients to these healthcare-related infections (most often severe neutropenia in patients with haematological malignancies), and in part due to the often challenging intrinsic susceptibility pattern of the pathogens that potentially leads to delayed appropriate antifung ... | 2014 | 24102785 |
| culture condition-dependent metabolite profiling of aspergillus fumigatus with antifungal activity. | three sections of aspergillus (five species, 21 strains) were classified according to culture medium-dependent and time-dependent secondary metabolite profile-based chemotaxonomy. secondary metabolites were analysed by liquid chromatography-electrospray ionisation tandem mass spectrometry (lc-esi-ms-ms) and multivariate statistical methods. from the aspergillus sections that were cultured on malt extract agar (mea) and czapek yeast extract agar (cya) for 7, 12, and 16 d, aspergillus sections fum ... | 2013 | 23537878 |
| skin conditions: common skin rashes in infants. | infants exhibit many skin rashes. erythema toxicum neonatorum presents as erythematous macules, papules, and pustules on the face, trunk, and extremities; it typically resolves spontaneously within 1 week. neonatal acne presents as comedones or erythematous papules on the face, scalp, chest, and back. infantile acne is similar but starts after the neonatal period. both conditions typically resolve spontaneously; failure to resolve within 1 year warrants evaluation for androgen excess. neonatal c ... | 2013 | 23600337 |
| screening of microbial contamination and antimicrobial activity of sea cucumber holothuria polii. | microbiological studies were carried out on microbial contamination and antimicrobial activity of sea cucumber holothuria polii collected from mediterranean sea at abu-kir shore of alexandria, egypt. the obtained results revealed the presence of isolates of five human gram-negative pathogenic bacteria, representing five genera were identified to species level, including, esherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, salmonella sp. and shigella sp. in addition, an yeast candida ... | 2013 | 22653870 |
| treating seborrheic dermatitis: review of mechanisms and therapeutic options. | seborrheic dermatitis is one of those conditions that dermatologists and patients alike tend to find a routine for, and in many cases those routines are hard to break. and, unlike the new treatment paradigms for eczema, acne, and even actinic keratoses, combination therapies for addressing the disease process typically have not been a part of the approach to treating seborrheic dermatitis. however, with the advent of new therapies and vehicles as well as a better understanding of how neutrophils ... | 2013 | 23884493 |
| the role of l-dopa on melanization and mycelial production in malassezia furfur. | melanins are synthesized by organisms of all biological kingdoms and comprise a heterogeneous class of natural pigments. certain of these polymers have been implicated in the pathogenesis of several important human fungal pathogens. this study investigated whether the fungal skin pathogen malassezia furfur produces melanin or melanin-like compounds. a melanin-binding monoclonal antibody (mab) labelled in vitro cultivated yeast cells of m. furfur. in addition, melanization of malassezia yeasts an ... | 2013 | 23762233 |
| identification and speciation of malassezia in patients clinically suspected of having pityriasis versicolor. | malassezia is a lipid-dependent yeast known to cause pityriasis versicolor, a chronic, recurrent superficial infection of skin and present as hypopigmented or hyperpigmented lesions on areas of skin. if not diagnosed and treated, it may lead to disfigurement of the areas involved and also result in deep invasive infections. | 2013 | 23723483 |
| epidemiological characteristics of malassezia folliculitis and use of the may-grünwald-giemsa stain to diagnose the infection. | various bacterial, fungal, parasitic, and viral pathogens can cause folliculitis, which is often mistakenly treated with antibiotics for months or even years. a laboratory diagnosis is required before therapy can be planned. here, we describe the prevalence and risk factors, as well as the clinical, cytological, and mycological characteristics, of patients with malassezia folliculitis (mf) in adana, turkey. we also report the treatment responses of the mf patients and describe the malassezia spp ... | 2013 | 23706503 |
| epigenetic regulation of il-8 and β-defensin genes in human keratinocytes in response to malassezia furfur. | 2013 | 23519334 | |
| in vitro antifungal activity of topical and systemic antifungal drugs against malassezia species. | the strict nutritional requirements of malassezia species make it difficult to test the antifungal susceptibility. treatments of the chronic and recurrent infections associated with malassezia spp. are usually ineffective. the objective of this study was to obtain in vitro susceptibility profile of 76 clinical isolates of malassezia species against 16 antifungal drugs used for topical or systemic treatment. isolates were identified by restriction fragment length polymorphism. minimal inhibitory ... | 2013 | 23496653 |
| enhanced efficacy and sensory properties of an anti-dandruff shampoo containing zinc pyrithione and climbazole. | dandruff is a common complaint and is suffered by as much as half of the population at some time post puberty. the condition is characterized by the presence of flakes on the scalp and in the hair, and is often accompanied by itch. the most common treatment for dandruff is the use of shampoo formulations that contain fungistatic agents such as zinc pyrithione (zpt) and octopirox. whilst most antidandruff shampoos are effective in resolving the symptoms of dandruff these shampoos can often result ... | 2013 | 22970742 |
| characterization of tryptophan aminotransferase 1 of malassezia furfur, the key enzyme in the production of indolic compounds by m. furfur. | malassezia yeasts are responsible for the widely distributed skin disease pityriasis versicolor (pv), which is characterized by a hyper- or hypopigmentation of affected skin areas. for malassezia furfur, it has been shown that pigment production relies on tryptophan metabolism. a tryptophan aminotransferase was found to catalyse the initial catalytic step in pigment formation in the model organism ustilago maydis. here, we describe the sequence determination, recombinant production and biochemic ... | 2013 | 24118363 |
| [1% econazole hair-shampoo in the treatment of pityriasis capitis; a comparative study versus zinc-pyrithione shampoo]. | on the basis of the assumption that pityrosporum ovale is an important pathogenic factor in the aetiology of pityriasis simplex capitis (dandruff), the authors intended to evaluate the efficacy and tolerability of econazole (1% hair-shampoo) in the treatment of this scalp disease. dandruff could be considered a problem more from a cosmetic than from a medical point of view; for this reason a conventional anti-dandruff hair-shampoo containing zinc-pyrithione was selected as a control. in this ope ... | 2013 | 2638641 |
| [pathogenic role of pityrosporum ovale in dermatitis seborrheica and pityriasis versicolor]. | 2013 | 2960581 | |
| clinical efficacy and safety of a pharmacopial polyherbal unani formulation in pityriasis versicolor: a comparative randomized single-blind study. | pityriasis versicolor (pv) is a common superficial fungal infection of skin caused by the fungus, malassezia furfur. it can occur at any age but occurs mainly during adolescence and typically presents with hypopigmented or hyperpigmented scaling plaques, generally on the trunk and upper arms. it often poses a therapeutic challenge. in the unani system of medicine, many herbal drugs are used empirically for its treatment. | 2012 | 22871048 |
| natural oils enhance il-10 and ifn-γ production by human pbmcs cultured with malassezia furfur. | malassezia furfur is a lipophilic yeast that causes skin disease. | 2012 | 22735798 |
| the antifungal effect of light emitting diode on malassezia yeasts. | malassezia (m.) species are members of the normal part of the skin flora, but they might induce or be involved with various cutaneous diseases. although the role of malassezia in the pathogenesis of cutaneous diseases is not fully understood, recent studies have shown that decreased density of malassezia led to improvement of these diseases. | 2012 | 22551719 |
| hair-loss preventing effect of grateloupia elliptica. | this study was conducted to evaluate the effect of grateloupia elliptica, a seaweed native to jeju island, korea, on the prevention of hair loss. when immortalized rat vibrissa dermal papilla cells were treated with extract of g. elliptica, the proliferation of dermal papilla cells significantly increased. in addition, the g. elliptica extract significantly inhibited the activity of 5α-reductase, which converts testosterone to dihydrotestosterone (dht), a main cause of androgenetic alopecia. on ... | 2012 | 24116284 |
| classification of cryptococcus neoformans and yeast-like fungus isolates from pigeon droppings by colony phenotyping and its genotyping and their seasonal variations in korea. | cryptococcus neoformans (c neoformans) is a frequent cause of invasive fungal disease in immunocompromised human hosts. ninety-eight samples of pigeon droppings were collected from the pigeon shelters in seoul, and cultured on birdseed agar (bsa) and sabouraud dextrose agar (sda). one hundred yeast-like colonies were selected and identified via phenotype characteristics, such as colony morphology and biochemical characteristics. this was then followed with genotyping via sequencing of the intern ... | 2012 | 22545529 |
| prevalence of fungal skin infections in iranian wrestlers. | fungal infections are one of the most common skin infections. athletes, especially in contact sports such as wrestlers are the group at risk of fungal skin infections (fsi). the aim of this study was to determine prevalence of fsi and some effective factors in wrestlers in tehran, iran. | 2012 | 23785573 |
| [case report; a case of malassezia furfur fungemia induced by repeated administration of liposomal flurbiprofen axetil]. | 2012 | 23342595 | |
| Rare opportunistic (non-Candida, non-Cryptococcus) yeast bloodstream infections in patients with cancer. | Rare opportunistic (non-Candida, non-Cryptococcus) yeast bloodstream infections (ROYBSIs) are rare, even in cancer patients. | 2012 | 22101079 |
| peptides of the constant region of antibodies display fungicidal activity. | synthetic peptides with sequences identical to fragments of the constant region of different classes (igg, igm, iga) of antibodies (fc-peptides) exerted a fungicidal activity in vitro against pathogenic yeasts, such as candida albicans, candida glabrata, cryptococcus neoformans, and malassezia furfur, including caspofungin and triazole resistant strains. alanine-substituted derivatives of fungicidal fc-peptides, tested to evaluate the critical role of each residue, displayed unaltered, increased ... | 2012 | 22470523 |
| profile of dermatophytic and other fungal infections in jaipur. | the common cause of skin infections are dermatophytes and opportunistic fungi. aim of present study is to find predominant etiological agent of dermatophytoses and to isolate various fungal agents from clinical samples of patients with different mycoses and clinical samples from 260 patients were subjected to potassium hydroxide (koh) examination and culture isolation; causative agents were identified macroscopically and microscopically. one hundred sixty three (62.7%) were found to be positive ... | 2011 | 23729893 |
| correlation between serum 25-hydroxyvitamin d levels and severity of atopic dermatitis in children. | vitamin d deficiency could be associated with the prevalence of atopic dermatitis (ad). | 2011 | 21087229 |
| malassezia dermatitis in dogs in brazil: diagnosis, evaluation of clinical signs and molecular identification. | skin carriage and quantification of malassezia yeasts were evaluated in 180 healthy dogs (group 1) and 117 dogs with clinical signs (pruritus, erythema, lichenification/seborrhoea, excoriations and alopecia) that could be related to malassezia dermatitis (group 2) in brazil. the lesions in the group 2 dogs were evaluated using cadesi-03 scores. samples were collected from five different anatomical areas. direct examination was performed using the tape strip technique, and results were expressed ... | 2011 | 20609207 |
| contact allergy to corticosteroids and malassezia furfur in seborrhoeic dermatitis patients. | background seborrhoeic dermatitis (sd) is a chronic skin disease, requiring long-term treatment, which might promote sensitization. malassezia furfur (mf) plays an important role in seborrhoeic dermatitis. objectives the aim of this study was to determine the frequency of contact sensitivity in sd patients. patients and methods a total of 100 patients and 20 healthy controls (hc) were investigated: 50 suffering from sd with no previous local corticosteroid treatment (sdn), 50 sd patients trea ... | 2011 | 20854306 |
| prevalencia de especies de malassezia en pacientes con pitiriasis versicolor en rosario, argentina. | malassezia species are considered opportunistic yeasts of increasing clinical importance. these lipophilic yeasts are associated with various human diseases, especially pityriasis versicolor (pv), a chronic superficial scaling dermatomycosis. the aim of this study was to isolate, identify and analyze the distribution of the different species of malassezia in patients with pv in rosario city (argentina). a total of 264 clinical samples were studied. isolates were identified on the basis of micros ... | 2011 | 21419859 |
| could malassezia yeasts be implicated in skin carcinogenesis through the production of aryl-hydrocarbon receptor ligands? | malassezia yeasts are found on the skin of all humans and many warm-blooded animals. in vitro they have the ability to synthesize potent ligands (indolo[3,2-b]carbazole, malassezin and indirubin) of the aryl-hydrocarbon receptor (ahr; synonym: dioxin receptor) when the sweat contained l-tryptophan is used as the single nitrogen source. the production of these ahr-ligands has been associated with pathogenic strains of a certain malassezia species (malassezia furfur) but recent evidence shows that ... | 2011 | 21444158 |
| malassezia furfur fungaemia in a neonatal patient detected by lysis-centrifugation blood culture method: first case reported in italy. | 2011 | 21535454 | |
| antimicrobial and anti-inflammatory effects of cecropin a(1-8)-magainin2(1-12) hybrid peptide analog p5 against malassezia furfur infection in human keratinocytes. | the lipophilic fungus malassezia furfur (m. furfur) is a commensal microbe associated with several chronic diseases such as pityriasis versicolor, folliculitis, and seborrheic dermatitis. because m. furfur-related diseases are difficult to treat and require prolonged use of medications, the treatment for m. furfur-related skin diseases is supposed to gain control over m. furfur growth and the inflammation associated with it, as well as to prevent secondary infections. in this study, we investiga ... | 2011 | 21593770 |
| genetic and biological features of catheter-associated malassezia furfur from hospitalized adults. | malassezia furfur, an etiological agent of catheter-associated fungemia, requires long-chain fatty acids for in vitro growth. we examined the applicability of rdna sequence analysis, autoaggregation testing in liquid culture, utilization of parenteral lipid emulsions, and phospholipase activity for discrimination of catheter-associated m. furfur strains. the rdna sequence types of catheter-associated m. furfur strains were distinct from those of other isolates. all m. furfur isolates recovered f ... | 2011 | 21619498 |
| inhibitory effect of formulated lemongrass shampoo on malassezia furfur: a yeast associated with dandruff. | lemongrass (cymbopogon citratus stapf) has been used in cooking and in many traditional medicines; the essential oil contains citral as a major constituent. this study evaluated the antifungal activity of lemongrass oil against malassezia furfur, an opportunistic yeast associated with dandruff, by using a broth dilution assay. from the minimum fungicidal concentration (mfc) obtained, the oil was then incorporated at different percentages into shampoo formulations. the formulated shampoos were ke ... | 2011 | 21710859 |
| toll-like receptor 9 modulates macrophage antifungal effector function during innate recognition of candida albicans and saccharomyces cerevisiae. | phagocytic responses are critical for effective host defense against opportunistic fungal pathogens. macrophages sample the phagosomal content and orchestrate the innate immune response. toll-like receptor 9 (tlr9) recognizes unmethylated cpg dna and is activated by fungal dna. here we demonstrate that specific triggering of tlr9 recruitment to the macrophage phagosomal membrane is a conserved feature of fungi of distinct phylogenetic origins, including candida albicans, saccharomyces cerevisiae ... | 2011 | 21947771 |
| confluent and reticulated papillomatosis: clinical and histopathological study of 10 cases from lebanon. | background confluent and reticulate papillomatosis (crp) is a rare disorder that has mostly been described in case reports and limited case series. studies on this condition from our region are lacking. objective/methods to describe the clinical and histopathological findings, as well as response to treatment of all patients diagnosed with crp at the american university of beirut medical center (aub-mc) between 1999 and 2009, and to compare our findings with those published in the literature. ... | 2011 | 22050084 |
| Oral itraconazole for the treatment of severe seborrhoeic dermatitis. | Seborrheic dermatitis (SD) is an inflammatory skin disorder in which colonies of Malassezia furfur have been found in affected areas. | 2011 | 22121267 |
| identification of malassezia yeast species isolated from patients with pityriasis versicolor. | pityriasis versicolor (pv) is a disease with worldwide distribution. twelve different species of malassezia yeast have been described. the objective of this study was to determine which species of malassezia are more prevalent in patients with pityriasis versicolor. samples were collected by scraping the lesions of 87 patients with a clinical suspicion of pityriasis versicolor. the samples were then submitted to fungal microscopy and culture to identify the species. the species found were: malas ... | 2011 | 21987156 |
| glycine as a regulator of tryptophan-dependent pigment synthesis in malassezia furfur. | the effects of the addition of different amino nitrogens on growth, morphology and secondary metabolism of malassezia furfur were investigated. after primary culture on dixon agar, m. furfur cbs 1878 was transferred into a fluid medium together with the nitrogen sources, glycine (gly) or tryptophan (trp), or a combination of both. growth was measured by means of a direct cell counting method and pigment synthesis was photometrically assessed. addition of glycine resulted in an exponential increa ... | 2011 | 19702622 |
| antimicrobial activity of hymenaea martiana towards dermatophytes and cryptococcus neoformans. | the biological activity of crude extract and fractions of hymenaea martiana was evaluated against a panel of human pathogenic fungi. the crude extracts and hydroalcoholic fractions (e) showed a high activity against cryptococcus neoformans species complex isolates with mics between 2 and 64 μg ml(-1). the methanolic (c) and butanolic (d) fractions were the most active against trichopyton rubrum, trichopyton mentagrophytes and microsporum canis with mics between 8 and 256 μg ml(-1). none of the e ... | 2010 | 19563478 |
| rapd differentiation of malassezia spp. from cattle, dogs and humans. | the molecular characterization of malassezia spp. isolates from animals and humans has not been thoroughly studied. we have analysed the dna profile by random amplified polymorphic dna (rapd)-pcr to compare the genetic diversity between isolates from the external ears of cattle, dogs and humans. the analysis of electrophoretic profiles on 8% polyacrylamide gel and their phenograms showed genetic heterogeneity between rapd profiles of malassezia furfur and malassezia slooffiae isolates from human ... | 2010 | 19298360 |
| c-type lectin langerin is a beta-glucan receptor on human langerhans cells that recognizes opportunistic and pathogenic fungi. | langerhans cells (lcs) lining the stratified epithelia and mucosal tissues are the first antigen presenting cells to encounter invading pathogens, such as viruses, bacteria and fungi. fungal infections form a health threat especially in immuno-compromised individuals. lcs express c-type lectin langerin that has specificity for mannose, fucose and glcnac structures. little is known about the role of human langerin in fungal infections. our data show that langerin interacts with both mannan and be ... | 2010 | 20097424 |
| identification of malassezia species isolated from iranian seborrhoeic dermatitis patients. | in recent years, the genus malassezia has come to be considered important in the etiology of seborrhoeic dermatitis (sed). the aim of present study was identification of malassezia species on the lesions of iranian sed patients. | 2010 | 20184091 |
| differentially expressed genes associated with tryptophan-dependent pigment synthesis in malassezia furfur- a comparison with the recently published genome of malassezia globosa. | summary malassezia (m.) furfur, a commensal organism found on the human skin, produces a wide range of pigments and fluorochromes when cultured with tryptophan as a sole nitrogen source. some compounds of this pigment metabolism may provide an explanation for clinical characteristics of pityriasis versicolor (pv), a frequent skin disease in humans characterised by long-lasting pigmentary changes. malassezia globosa is currently regarded as the causative agent of pv, but tryptophan-dependent pigm ... | 2010 | 20202114 |
| time-kill assay results for a linalool-hinokitiol-based eyelid cleanser for lid hygiene. | time-kill testing was performed for a linalool-hinokitiol-based eyelid cleanser against pseudomonas aeruginosa, moraxella catarrhalis, escherichia coli, serratia marcescens, staphylococcus aureus, methicillin-resistant s. aureus (mrsa), staphylococcus epidermidis, and pityrosporum ovale to evaluate its efficacy. | 2010 | 20308878 |
| prevalence of malassezia species in pityriasis versicolor lesions in northeast argentina. | malassezia species normally colonize the skin but they can change their saprophytic state and invade the stratum corneum as pathogens. | 2010 | 20346299 |
| inhibitory effects of fortunella japonica var. margarita and citrus sunki essential oils on nitric oxide production and skin pathogens. | a number of essential oils from citrus peels are claimed to have biological activities. citrus peel, called 'jin-pi', is used in traditional medicine for digestion, severe cold, and fever. however, the antibacterial activities against skin pathogens and anti-inflammatory effects of the essential oils of citrus sunki (jingyul) and fortunella japonica var. margarita (gumgyul) have not yet been described. therefore, in this study, the essential oils of the citrus species c. sunki (cse) and f. japon ... | 2010 | 20350876 |
| identification of malassezia species from tunisian patients with pityriasis versicolor. | pityriasis versicolor is caused by malassezia sp. it is a common worldwide mycosis. recently, eleven species are known of the malassezia genus, and are identified in vitro by their morphological characteristics, biochemical tests and by molecular biology. the aim of this study is the identification of malassezia species from tunisian patients with pityriasis versicolor. | 2010 | 20415164 |
| [pityriasis versicolor: isolation and identification of the main species of malassezia]. | species of the genus malassezia isolated were: malassezia sympodialis (16.66%), malassezia furfur (12.50%), malassezia globosa (11.45%), and malassezia slooffiae (2.10%). malassezia sympodialis predominated in the study. the species of malassezia identified did not show correlation with clinical variants and with the distribution of pityriasis versicolor lesions in relation to areas of the body. | 2010 | 20464101 |
| evaluation of microbial contamination associated with different preparation methods for neonatal intravenous fat emulsion infusion. | microbial contamination associated with different methods of neonatal intravenous fat emulsion (ivfe) preparation and delivery was evaluated. | 2010 | 20484215 |
| antimicrobial and cytotoxic activities of synthetically derived tambjamines c and e - j, be-18591, and a related alkaloid from the marine bacterium pseudoalteromonas tunicata. | in the first comprehensive biological assessment of the tambjamine class of marine alkaloids, synthetically derived samples of compounds 1-9 have been subjected to evaluation as antimicrobial agents and screened for their cytotoxic effects on various human cancer cell lines. most were strongly active against the fungus malassezia furfur (>amphotericin b) and showed considerable, but non-selective, antiproliferative activity against both human cancer and normal cell lines. tambjamines i and j (6 ... | 2010 | 20491087 |
| genetic polymorphism of malassezia furfur isolates from han and tibetan ethnic groups in china using dna fingerprinting. | reported isolation rates of malassezia yeast from human skin show geographic variations. in china, the populations of the han (1,182.95 million) and tibetan (5.41 million) ethnic groups are distributed over 9.6 and 3.27 million square kilometers respectively, making biodiversity research feasible and convenient. malassezia furfur clinical strains (n = 29) isolated from different individuals, with or without associated dermatoses, of these two ethnic groups (15 han and 12 tibetan) were identified ... | 2010 | 20507265 |
| av119, a natural sugar from avocado gratissima, modulates the lps-induced proinflammatory response in human keratinocytes. | keratinocytes play an active role in innate immune responses by secreting a variety of cytokines and chemokines. the release of critical proinflammatory cytokines, which are necessary to activate the immune response, is induced by the stimulation of toll-like receptors (tlrs) by molecules present on pathogenic micro-organisms such as lipopolysaccharide (lps). av119, a patented blend of avocado sugars, induced the aggregation of malassezia furfur, a dimorphic, lipid-dependent yeast that is part o ... | 2010 | 20936426 |
| comparative analysis of the frequency, distribution and population sizes of yeasts associated with canine seborrheic dermatitis and healthy skin. | the purpose of this study was to investigate the diversity of yeast associated with the degree of canine seborrheic dermatitis (sd) by anatomical sites. fifty-seven samples were divided as 17 healthy skin, 20 with primary seborrheic dermatitis (psd), and 20 with secondary seborrheic dermatitis (ssd). yeast isolation and characterization were carried out based on microscopical features and biochemical properties. dna analysis at the internal transcribed spacer i of 26s rdna region was utilized fo ... | 2010 | 20961712 |
| physiological and molecular characterization of atypical lipid-dependent malassezia yeasts from a dog with skin lesions: adaptation to a new host? | three lipid-dependent malassezia isolates (here named 114a, 114b and 114c) recovered from a dog with skin lesions were phenotypically and genotypically characterized. all presented ovoid cells and buds formed on a narrow base. most of the results from physiological tests were consistent with those of malassezia furfur. the phylogenetic analysis of its-1 and lsu nucleotide sequences was concordant in placing all three clinical malassezia isolates close to m. furfur. however, the phylogenetic data ... | 2010 | 21070187 |
| potent antimicrobial action of triclosan-lysozyme complex against skin pathogens mediated through drug-targeted delivery mechanism. | triclosan (tcs), an antimicrobial agent that inhibits bacterial fatty acid synthesis by blocking the active site of enoyl-acp reductase (fabi), is a water-insoluble agent that limits its therapeutic candidacy. we have recently shown that the water solubility and antimicrobial activity of tcs were greatly enhanced when complexed to lysozyme (lz). this study is to examine the therapeutic potential of triclosan-lysozyme (t-lz) complex against common skin pathogens expressing different levels of fab ... | 2010 | 21078387 |
| isolation and characterization of malassezia spp. in healthy swine of different breeds. | malassezia spp. genus is represented by several lipophilic yeasts, normally present on the skin of many warm-blooded vertebrates, including man. swine are one of the less investigated animal species. the aim of the present work was to study the occurrence of malassezia spp. in the external ear canal of 408 healthy swine of different breeds, under different breeding conditions. for this purpose n. 185 free-ranging wild boars, n. 107 large size pigs and 116 cinta senese breed were selected. animal ... | 2010 | 19709823 |
| antifungal activity of the aqueous extract of ilex paraguariensis against malassezia furfur. | malassezia furfur is a lipodependent, dimorphic and saprophyte fungus which causes pityriasis versicolor, dandruff and seborrheic dermatitis in humans. the drugs available to treat this fungal infection are few. these drugs are highly toxic and are costly when used in prolonged treatments. for these reasons, it is necessary to find new compounds to treat these infections. ilex paraguariensis st hilaire is a plant that grows in argentina, brazil and paraguay. the aim of this study was to evaluate ... | 2010 | 19827026 |
| synthesis and antimicrobial activity of long-chain 3,4-epoxy-2-alkanones. | 3,4-epoxy-2-dodecanone, a major component in the preorbital gland of the african grey duiker (sylvicapra grimmia), showed antimicrobial activity in preliminary tests. the c(11) to c(17) homologues of this compound were prepared and their activity against several pathogenic dermal bacteria and fungi was tested. 3,4-epoxy-2-dodecanone and 3,4-epoxy-2-tridecanone inhibited the growth of trichophyton mentagrophytes at 25 îg/ml. moderate inhibition of the growth of the bacteria propionibacterium acne ... | 2010 | 21179314 |
| [pityrosporum ovale in seborrheic keratoses]. | 2010 | 2936294 | |
| seborrhoeic dermatitis. | seborrhoeic dermatitis affects at least 10% of the population. malassezia (pityrosporum) ovale is thought to be the causative organism, and causes inflammation by still poorly defined mechanisms. seborrhoeic dermatitis tends to relapse after treatment. | 2010 | 21418692 |
| hypopigmented pityriasis versicolor on becker's naevus : hope for new method of treatment ? | a case of hypopigmented pityriasis versicolor superimposed on pre existing becker's naevus associated with congenital melanocytic naevus is being reported for its rarity. the possible role of dicarboxylic acid and other free radicles produced by pityrosporum ovale in treating becker's naevus is also suggested. | 2010 | 20921743 |
| in vitro activity of celery essential oil against malassezia furfur. | antifungal activity of celery essential oil against malassezia furfur was investigated using broth microdilution and vapor contact methods. potent antifungal activity was evident using both methods. fungicidal activity was revealed in the vapor contact method. | 2009 | 23983510 |
| evaluation of a nonsteroidal topical cream in a guinea pig model of malassezia furfur infection. | malassezia furfur is an important causal factor for seborrheic dermatitis, and topical antifungal therapy is an effective treatment approach. this study assessed the antifungal activity of promiseb topical cream (promius pharma, llc, bridgewater, nj), a novel nonsteroidal prescription medical device cream, in the m furfur-infected skin model for guinea pigs. guinea pigs (n = 28) were divided into 4 groups and infected with m furfur for 7 days. on day 8, the first group of animals was sacrificed. ... | 2009 | 19878779 |