Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| assessing the progression of chronic periodontitis using subgingival pathogen levels: a 24-month prospective multicenter cohort study. | the diagnosis of the progression of periodontitis presently depends on the use of clinical symptoms (such as attachment loss) and radiographic imaging. the aim of the multicenter study described here was to evaluate the diagnostic use of the bacterial content of subgingival plaque recovered from the deepest pockets in assessing disease progression in chronic periodontitis patients. | 2017 | 28093069 |
| analysis of the expression of nlrp3 and aim2 in periapical lesions with apical periodontitis and microbial analysis outside the apical segment of teeth. | to detect the distribution and expression levels of the nucleotide-binding oligomerization domain-like receptor protein 3 (nlrp3) and the absent in melanoma 2 (aim2) inflammasomes in periapical lesions and to analyse the possible microbial stimuli outside of teeth. | 2017 | 28193569 |
| comparison of nonsurgical periodontal therapy with oral hygiene instruction alone for chronic periodontitis. | we evaluated changes in clinical variables and microbiological profiles of periodontopathogens among 56 patients with moderate to severe cp who were randomly assigned to oral hygiene instruction (ohi; n = 28) or nonsurgical periodontal treatment (nspt; n = 28). periodontal variables were assessed and subgingival plaque samples were obtained from deep pockets (≥5 mm) at baseline and 3 months after treatment. real-time polymerase chain reaction was used to quantify actinobacillus actinomycetemcomi ... | 2017 | 28367891 |
| association between specific periodontal pathogens, toll-like receptor-4, and nuclear factor-κb expression in placental tissues of pre-eclamptic women with periodontitis. | the aim of the present study was to determine the association between the presence of specific periodontal pathogens, toll-like receptor-4 (tlr-4), and nuclear factor-κb (nf-κb) expression in the placental tissues of pre-eclamptic women. | 2017 | 28349674 |
| effect of opposing implant prostheses on periodontal pathogens in dentures: a pilot study. | an understanding of the presence of periodontal pathogens in denture plaque is important for the treatment of patients with edentulism. however, current data are limited and inconclusive. | 2017 | 28126355 |
| rt-pcr quantification of periodontal pathogens in crack users and non-users. | to compare counts of aggregatibacter actinomycetemcomitans, prevotella intermedia, porphyromonas gingivalis and fusobacterium nucleatum between crack users and non-users. | 2017 | 27982490 |
| thermoreversible gel for intrapocket delivery of green tea catechin as a local drug delivery system: an original research. | the periodontal therapies along with systemic antibiotic therapy aim at eliminating the subgingival microbiota to arrest the progression of periodontal diseases. the complete elimination is often difficult, and thus the probability of repopulation after periodontal therapy is also high. the objectives of the study are to develop in situ thermoreversible gelling system of green tea catechins suitable for periodontal pocket administration, which would act as an adjunct to mechanical periodontal th ... | 2017 | 27833893 |
| comparison of two different sampling methods for subgingival plaque: subgingival paper points or mouthrinse sample? | the collection of subgingival plaque samples with paper points is time-consuming and accident-sensitive. however, the collection of saliva is simple and contains pathogens of all intraoral surfaces. the aim of this study is to investigate whether a sampling strategy with mouthrinse (mouthrinse sample [msp]; test) leads to results comparable with standard sampling method (multiple site test from the deepest pocket of each quadrant [mt4]; control). | 2017 | 27786617 |
| microbial characteristics of peri-implantitis: a case-control study. | the aim of this case-control study is to compare oral microbiologic characteristics of patients with healthy peri-implant conditions and patients with peri-implantitis and to explore the influence of various patient- and implant-related factors on microbiologic characteristics. | 2017 | 27666672 |
| a double-blind randomized trial comparing implants with laser-microtextured and machined collar surfaces: microbiologic and clinical results. | the purpose of this study was to compare the clinical outcome of and determine the differences in periodonto-pathogenic microbiota around two types of implant collar surfaces: laser-microtextured (test) vs machined (control). | 2017 | 27632268 |
| antimicrobial efficacy of tulsi leaf (ocimum sanctum) extract on periodontal pathogens: an in vitro study. | periodontitis is an infection of the periodontal complex with severe forms of disease associated with specific bacteria colonizing the subgingival area. widespread use of drugs has resulted in the emergence of side effects, uncommon infections, and resistance. plant medicine like tulsi has been used in many clinical conditions, and it appears to be a suitable alternative to manage conditions affecting the oral cavity. hence, the objective was to assess the in vitro antimicrobial activity of tuls ... | 2017 | 27143825 |
| evaluation of a hydrophobic gel adhering to the gingiva in comparison with a standard water-soluble 1% chlorhexidine gel after scaling and root planing in patients with moderate chronic periodontitis. a randomized clinical trial. | to evaluate the clinical, microbiological and enzymatic activity of a hydrophobic chlorhexidine-based gingiva-adhering gel containing herbal ingredients, compared with a commercially available 1% chlorhexidine water-soluble gel, during non-surgical therapy of moderate chronic periodontitis. | 2017 | 26053503 |
| significant increase of oral bacteria in the early pregnancy period in japanese women. | oral microflora during pregnancy is critical to oral health care in the mother and her child. we examined the changes in the oral microbiota between pregnancy and nonpregnancy periods. | 2017 | 26345599 |
| determination of antibacterial activity of green coffee bean extract on periodontogenic bacteria like porphyromonas gingivalis, prevotella intermedia, fusobacterium nucleatum and aggregatibacter actinomycetemcomitans: an in vitro study. | the aim of this study was to evaluate the antibacterial activity of pure green coffee bean extract on periodonto pathogenic bacteria porphyromonas gingivalis (pg), prevotella intermedia (pi), fusobacterium nucleatum (fn) and aggregatibacter actinomycetemcomitans (aa). | 2017 | 26097349 |
| prevalence of eight putative periodontal pathogens in atherosclerotic plaque of coronary artery disease patients and comparing them with noncardiac subjects: a case-control study. | the study was aimed to assess the prevalence of periodontal pathogens namely tannerella forsythia (t.f), campylobacter rectus (c.r), eikenella corrodens (e.c), porphyromonas gingivalis (p.g), treponema denticola (t.d), prevotella nigrescens (p.n) ,aggregatibacter actinomycetemcomitans (a.a), p.g (fi ma gene) and prevotella intermedia (p.i), in the subgingival and the atheromatous plaque of patients with coronary artery disease (cad), and comparing them with the noncardiac subjects thereby indica ... | 2017 | 26096116 |
| periodontal bacteria in the genital tract: are they related to adverse pregnancy outcome? | one of the most important factors implicated in preterm birth (ptb) is acute genitourinary tract infection. the bacteria causing chronic periodontal inflammation include gram-negative rods and anaerobes similar to those found in women with bacterial vaginosis. the aim of this prospective study is to investigate the relationship between oral and vaginal microflora and preterm low birth weight. real-time polymerase chain reaction was used to detect both the presence and level of six periodontitis- ... | 2017 | 24355228 |
| benefits of bifidobacterium animalis subsp. lactis probiotic in experimental periodontitis. | this study evaluates effects of topical administration of probiotic bacteria of the genus bifidobacterium on experimental periodontitis (ep) in rats. | 2017 | 27660886 |
| performance of two blood culture systems to detect anaerobic bacteria. is there any difference? | we studied the performance characteristics of two blood culture (bc) bottles/systems, (i) bact/alert-fn plus/3d (biomérieux, marcy l'étoile, france) and (ii) bactec-lytic/9000 (becton dickinson, sparks, usa) for detection of growth and time-to-positivity (ttp) against a balanced and diverse collection of anaerobic bacterial strains (n = 48) that included reference strains (n = 19) and clinical isolates (n = 29) of 32 species (15 gram-negative and 17 gram-positive). standard suspension of bacteri ... | 2017 | 28279857 |
| effect of photodynamic therapy in combination with various irrigation protocols on an endodontic multispecies biofilm ex vivo. | to analyse the antibacterial effect of photodynamic therapy (pdt) in combination with various irrigation protocols on a multispecies biofilm in root canals ex vivo. | 2017 | 28276583 |
| influence of glycemic control on the levels of subgingival periodontal pathogens in patients with generalized chronic periodontitis and type 2 diabetes. | this study evaluated the influence of glycemic control on the levels and frequency of subgingival periodontal pathogens in patients with type 2 diabetes mellitus (dm) and generalized chronic periodontitis (chp). | 2017 | 28198980 |
| microbial colonization at the implant-abutment interface and its possible influence on periimplantitis: a systematic review and meta-analysis. | the aim of this systematic review and meta-analysis was to evaluate the microbial colonization at the implant-abutment interfaces (iai) on bone-level implants and to identify possible association with peri-implant conditions. | 2017 | 28359872 |
| effect of gallium-arsenic laser on photosensitized periodontopathic anaerobic organisms: an in vitro study. | the mainstay of periodontal therapy is mechanical removal of subgingival plaque. there is considerable interest in supplementing it with the use of antibiotics and antiseptics. many drawbacks are associated with these adjunctive pharmacological regimens such as development of resistance to antibiotics and disruption of microflora of the gastrointestinal tract. hence, alternate means of killing subgingival bacteria are clearly desirable. one such method is the use of laser. | 2017 | 28298816 |
| quantitative detection of periodontopathic bacteria in lower respiratory tract specimens by real-time pcr. | the presence of common periodontopathic bacteria, the fusobacterium nucleatum-periodonticum-simiae group, prevotella intermedia, and porphyromonas gingivalis was determined from respiratory tract specimens of bacterial pneumonia by real-time pcr using universal and species-specific taqman probe/primer sets. 42 patients with infectious pneumonia and 45 patients without infectious pneumonia were retrospectively enrolled in clinical studies. periodontopathic bacterial dna was found in 57.1% cases o ... | 2017 | 27894820 |
| bone remodeling around implants with external hexagon and morse-taper connections: a randomized, controlled, split-mouth, clinical trial. | to evaluate clinical, radiographic, microbiologic, and biomechanical parameters related to bone remodeling around implants with external hexagon (eh) and morse-taper (mt) connections. | 2017 | 27353076 |
| periodontitis induced by porphyromonas gingivalis drives periodontal microbiota dysbiosis and insulin resistance via an impaired adaptive immune response. | to identify a causal mechanism responsible for the enhancement of insulin resistance and hyperglycaemia following periodontitis in mice fed a fat-enriched diet. | 2017 | 26838600 |
| azithromycin buccal patch in treatment of chronic periodontitis. | this study aims to explore the clinical, microbiological, and biochemical impact of azithromycin (azm) buccal patch in chronic generalized patients as a monotherapy as well as an adjunct to nonsurgical therapy. | 2017 | 27127325 |
| heme acquisition mechanisms of porphyromonas gingivalis - strategies used in a polymicrobial community in a heme-limited host environment. | porphyromonas gingivalis, a main etiologic agent and key pathogen responsible for initiation and progression of chronic periodontitis requires heme as a source of iron and protoporphyrin ix for its survival and the ability to establish an infection. porphyromonas gingivalis is able to accumulate a defensive cell-surface heme-containing pigment in the form of μ-oxo bisheme. the main sources of heme for p. gingivalis in vivo are hemoproteins present in saliva, gingival crevicular fluid, and erythr ... | 2017 | 26662717 |
| antimicrobial activity of aqueous extracts from four plants on bacterial isolates from periodontitis patients. | four aqueous extracts of different plant organs are the following: artemisia herba-alba, opuntia ficus-indica, camellia sinensis and phlomis crinita were evaluated against two bacterial strains: porphyromonas gingivalis and prevotella intermedia, which are implicated in periodontal diseases. by using a disc method, these plant extracts demonstrated powerful bacterial activity against these gram-negative strains. the minimum inhibitory concentration values of the four plant extracts varied betwee ... | 2017 | 28386896 |
| [the relationship of molecular genetic markers with clinical signs and risk factors of periodontitis]. | the study revealed positive correlation between bleeding on probing and teeth loss risk with periodontal hypercolonization by porphyromonas gingivalis, prevotella intermedia and treponema denticola. pathological tooth mobility was associated with hypercolonization by p. intermedia and tannerella forsythensis. expression of il8, tnf-α, mmp8 and mmp9 genes was also assessed in patient groups divided according to the depth of periodontal pockets and-the severity of chronic periodontitis revealing i ... | 2017 | 27876716 |
| antimicrobial activity of the chloroform fraction of drynaria fortunei against oral pathogens. | drynaria fortunei (d. fortunei), widely used in traditional korean medicine, is reportedly effective in treating inflammation, hyperlipidemia, bone fractures, oxidative damage, arteriosclerosis, rheumatism, and gynecological diseases. the objective of this study was to evaluate the antibacterial effects of the chloroform fraction of d. fortunei (dfcf) and assess the synergistic effects of dfcf with antibiotics against bacterial pathogens. this was carried out by calculating the minimal inhibitor ... | 2017 | 28367899 |
| microbiological and ammp-8 findings depending on peri-implant disease in patients undergoing supportive implant therapy. | the aim of this study was to evaluate microbiological findings and ammp-8 level of peri-implant mucositis (m) and peri-implantitis (p) in patients undergoing supportive implant therapy (sit). eighty-nine patients with 171 implants were included. the case definitions were as follows: m: ppd ≥4mm, bop; p: ppd≥4mm, bop, radiographic bone loss ≥3.5mm. samples of peri-implant sulcular fluid (pisf) were taken from all peri-implant pockets at each implant to detect periodontal pathogens using pcr and a ... | 2017 | 28274501 |
| prevotella intermedia infection causing acute and complicated aortitis-a case report. | aortitis is a general term that refers to all conditions involving an inflammation of the aortic wall. this case report describes the surgical approach of a patient with infectious and symptomatic aortitis caused by the rare vector prevotella intermedia. | 2017 | 28249232 |
| genome sequence of prevotella intermedia suny ab g8-9k-3, a biofilm forming strain with drug-resistance. | prevotella intermedia has long been known to be as the principal etiologic agent of periodontal diseases and associated with various systemic diseases. previous studies showed that the intra-species difference exists in capacity of biofilm formation, antibiotic resistance, and serological reaction among p. intermedia strains. here we report the genome sequence of p. intermedia suny ab g8-9k-3 (designated atcc49046) that displays a relatively high antimicrobial resistant and biofilm-forming capac ... | 2017 | 27339856 |
| do quaternary ammonium monomers induce drug resistance in cariogenic, endodontic and periodontal bacterial species? | antibacterial monomers were developed to combat oral biofilm acids and caries; however, little is known on whether quaternary ammonium monomers (qams) would induce drug resistance in oral bacteria. the objective of this study was to investigate the effects of new antimicrobial monomers dimethylaminohexadecyl methacrylate (dmahdm) and dimethylaminododecyl methacrylate (dmaddm) on the induction of drug resistance in eight species of cariogenic, endodontic and periodontal bacteria for the first tim ... | 2017 | 28755761 |
| prevalence of periodontal pathogens in a group of participants from the middle east and north africa geographic region with minimal periodontal disease. | to assess the prevalence of the three putative periodontal pathogens such as aggregatibacter actinomycetemcomitans (a. a), porphyromonas gingivalis (p. g), and prevotella intermedia (p. i) in a group of arab participants from the middle east and north africa (mena) region who had minimal periodontal disease and no history of periodontal treatment and further to analyze the association among these three microorganisms. | 2017 | 28713765 |
| the association of periodontopathic bacteria levels in saliva and tongue coating with oral malodor in periodontitis patients. | to elucidate the association oral malodor with the levels of periodontopathic bacteria in saliva and tongue coating of periodontitis patients with oral malodor. | 2017 | 28674708 |
| effects of photodynamic therapy in periodontal treatment: a randomized, controlled clinical trial. | to evaluate the effects of photodynamic therapy (pdt) in the nonsurgical treatment of chronic periodontitis. | 2017 | 28667678 |
| the microbial changes in subgingival plaques of orthodontic patients: a systematic review and meta-analysis of clinical trials. | orthodontic treatment was found to have an impact on the quantity and constitution of subgingival microbiota. however, contradictory findings regarding the effects of fixed appliances on microbial changes were reported. the aim of this systematic review was to investigate the microbial changes in subgingival plaques of orthodontic patients. | 2017 | 28576147 |
| herpes simplex 1 and periopathogen role in peri-implantitis. | the objectives of this study were to compare the qualitative and quantitative profiles of herpes simplex virus type i (hsv-1) in implant surfaces between participants with peri-implantitis (pi) and healthy peri-implant tissues and to quantitatively assess the relation between hsv-1 and periopathogens inside the microbiological profile associated with pi. | 2017 | 28512280 |
| antimicrobial effects of mastic extract against oral and periodontal pathogens. | various antimicrobial agents are widely used in the therapy of oral inflammatory diseases. however, their side effects and the appearance of drug resistance justify research on natural antimicrobial agents to target oral pathogens that are safe for the host. in the present study, antimicrobial properties of mastic extract on commensal and pathogenic oral bacteria, as well as its possible cytotoxic effect toward cells of epithelial and mesenchymal origin, were evaluated and compared with the comm ... | 2017 | 28067105 |
| 16s rdna analysis of periodontal plaque in chronic obstructive pulmonary disease and periodontitis patients. | this study investigated if chronic obstructive pulmonary disease (copd) is correlated with periodontitis via periodontal microbiota and if certain bacteria affect periodontitis as well as copd. moreover, the study investigated whether suffering from copd is associated with a decrease in the richness and diversity of periodontal microbiota. subgingival plaque was obtained from 105 patients. bacterial dna was isolated from 55 copd and 50 non-copd participants (either with or without periodontitis) ... | 2017 | 28748030 |
| simultaneous detection of oral pathogens in subgingival plaque and prostatic fluid of men with periodontal and prostatic diseases. | chronic prostatitis (cpr) and benign prostatic hyperplasia (bph) are complex inflammatory conditions for which etiologic determinants are still poorly defined. periodontitis is caused by subgingival colonizing bacteria in the oral cavity. the causal effect of periodontal disease on prostatic inflammation has not been established. the purpose of this study is to isolate oral pathogens from expressed prostatic secretions of patients with periodontal disease and cpr or bph. | 2017 | 28548883 |
| microbial profile comparisons of saliva, pooled and site-specific subgingival samples in periodontitis patients. | the purpose of this study was to compare microbial profiles of saliva, pooled and site-specific subgingival samples in patients with periodontitis. we tested the hypotheses that saliva can be an alternative to pooled subgingival samples, when screening for presence of periopathogens. | 2017 | 28800622 |
| dysbiosis in chronic periodontitis: key microbial players and interactions with the human host. | periodontitis is an extremely prevalent disease worldwide and is driven by complex dysbiotic microbiota. here we analyzed the transcriptional activity of the periodontal pocket microbiota from all domains of life as well as the human host in health and chronic periodontitis. bacteria showed strong enrichment of 18 kegg functional modules in chronic periodontitis, including bacterial chemotaxis, flagellar assembly, type iii secretion system, type iii crispr-cas system, and two component system pr ... | 2017 | 28623321 |
| effect of preparation method and storage period on the stability of saliva dna. | saliva is an attractive source for oral microbial detection and quantification since sampling is non-invasive and rapid. | 2017 | 28460249 |
| pathogenesis and treatment of bovine foot rot. | bovine foot rot (bfr) is an infectious disease of the interdigital skin and subcutaneous tissues of beef and dairy cattle that occurs under a variety of management and environmental settings. the anaerobic, gram-negative bacteria fusobacterium necrophorum, porphyromonas levii, and prevotella intermedia are commonly isolated from lesions. a multitude of host, agent, and environmental factors contribute to the development of bfr. initiation of systemic antimicrobial therapy early in the course of ... | 2017 | 28579042 |
| subgingival microbiome of gingivitis in chinese undergraduates. | to analyse the microbiome composition of health and gingivitis in chinese undergraduates with high-throughput sequencing. | 2017 | 28808698 |
| aggravation of collagen-induced arthritis by orally administered porphyromonas gingivalis through modulation of the gut microbiota and gut immune system. | porhyromonas gingivalis, a causative bacterium of periodontitis, is implicated in the etiology of rheumatoid arthritis (ra), mainly because of expressing peptidyl arginine deiminase (pad) that generates ra-related autoantigens. however, compared with other periodontopathic bacteria, the precise role of p. gingivalis in ra is largely unknown. we found that orally administered p. gingivalis changed the gut microbiome with concomitant elevation of serum endotoxin and inflammatory markers, and impai ... | 2017 | 28761156 |
| oral anaerobic bacteria in the etiology of ankylosing spondylitis. | ankylosing spondylitis (as) is associated with periodontitis. anti-porphyromonas gingivalis and anti-prevotella intermedia antibody titers were higher in patients with spondyloarthritis than in healthy people. sulfasalazine is an effective antibiotic treatment for as. moxifloxacin and rifamycin were also found to be significantly effective. the etiology hypothesis suggests that oral anaerobic bacteria such as porphyromonas spp and prevotella spp contribute to the disease. these bacteria have bee ... | 2017 | 28638241 |
| degradation of incretins and modulation of blood glucose levels by periodontopathic bacterial dipeptidyl peptidase 4. | severe periodontitis is known to aggravate diabetes mellitus, though molecular events related to that link have not been fully elucidated. porphyromonas gingivalis, a major pathogen of periodontitis, expresses dipeptidyl peptidase 4 (dpp4), which is involved in regulation of blood glucose levels by cleaving incretins in humans. we examined the enzymatic characteristics of dpp4 from p. gingivalis as well as two other periodontopathic bacteria, tannerella forsythia and prevotella intermedia, and d ... | 2017 | 28630069 |
| microbiome and microbial biofilm profiles of peri-implantitis: a systematic review. | this systematic review assesses the microbiological profiles of peri-implantitis, periodontitis and healthy implants based on studies that evaluated microbial biofilms and entire microbiomes to establish their similarities and differences. | 2017 | 28625077 |
| chair-side detection of prevotella intermedia in mature dental plaque by its fluorescence. | prevotella intermedia/nigrescens is one of the well-known pathogens causing periodontal diseases, and the red florescence excited by the visible blue light caused by the protoporphyrin ix in the bacterial cells could be useful for the chair-side detection. the aim of this study was to evaluated levels of periodontal pathogen, especially p. intermedia in clinical samples of red fluorescent dental plaque. | 2017 | 28457849 |
| effect of nitric oxide-releasing derivative of indomethacin on prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. | the purpose of this study was to investigate the influences of ncx 2121, a nitric oxide (no)-releasing derivative of indomethacin, upon the generation of proinflammatory mediators using murine macrophages activated by lipopolysaccharide (lps) isolated from prevotella intermedia, which is one of the pathogens implicated in periodontal diseases. inducible no synthase (inos)-derived no, il-1β and il-6 as well as their relevant mrna were significantly attenuated by ncx 2121 in raw264.7 cells activat ... | 2017 | 28822764 |
| dipeptidyl peptidase iv and quorum sensing signaling in biofilm-related virulence of prevotella aurantiaca. | biofilm formation and dipeptidyl peptidase iv (dppiv) enzyme activity contribute to the virulence of oral bacteria, and these virulence factors are partly regulated by quorum sensing signaling system. we recently demonstrated that estradiol regulates growth properties and dppiv activity of prevotella intermedia, prevotella nigrescens, and prevotella pallens. here, we examined the dppiv dependency of biofilm formation of prevotella aurantiaca. three strains (two clinical strains ahn 37505 and 375 ... | 2017 | 28821458 |
| agomelatine, a mt1/mt2 melatonergic receptor agonist with serotonin 5-ht2c receptor antagonistic properties, suppresses prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. | this study was performed in an attempt to examine the influence of agomelatine in mitigating the generation of proinflammatory mediators in raw264.7 murine macrophages exposed to lipopolysaccharide (lps) obtained from prevotella intermedia, a gram-negative anaerobic bacterium that is related with various types of periodontal diseases, and the molecular mechanisms behind its effects. | 2017 | 28578027 |
| biomarkers and bacteria around implants and natural teeth in the same individuals. | this cross-sectional study assesses cytokine levels in peri-implant crevicular fluid (picf)/gingival crevicular fluid (gcf) and a selection of subgingival/submucosal plaque bacteria from clinically healthy or diseased sites in the same individuals. | 2017 | 28440740 |
| black-pigmented anaerobic bacteria associated with ovine periodontitis. | periodontitis is a polymicrobial infectious disease that causes occlusion change, tooth loss, difficulty in rumination, and premature culling of animals. this study aimed to detect species of the genera porphyromonas and prevotella present in the periodontal pocket of sheep with lesions deeper than 5mm (n=14) and in the gingival sulcus of animals considered periodontally healthy (n=20). the presence of microorganisms was evaluated by polymerase chain reaction (pcr) using specific primers for por ... | 2017 | 28619155 |
| quantification by qpcr of pathobionts in chronic periodontitis: development of predictive models of disease severity at site-specific level. | currently, there is little evidence available on the development of predictive models for the diagnosis or prognosis of chronic periodontitis based on the qpcr quantification of subgingival pathobionts. our objectives were to: (1) analyze and internally validate pathobiont-based models that could be used to distinguish different periodontal conditions at site-specific level within the same patient with chronic periodontitis; (2) develop nomograms derived from predictive models. subgingival plaqu ... | 2017 | 28848499 |
| microbiological response to periodontal therapy and multivariable prediction of clinical outcome. | this study assessed the microbiological effects of a 2-phase antimicrobial periodontal therapy and tested microbiological, clinical, and biological markers as prognostic indicators for clinical success. | 2017 | 28844191 |
| specific periodontopathic bacterial infection affects hypertension in male cardiovascular disease patients. | hypertension (ht) is a systemic disorder that results in the decline of quality of life and death. while patients with periodontitis are at a high risk of ht, little causal information has been provided to date. to clarify the relationship, periodontopathic bacterial infection in cardiovascular patients with or without ht was evaluated. the subjects were patients with (n = 412) or without (n = 199) ht who attended tokyo medical and dental university hospital. blood examinations and periodontal m ... | 2017 | 28803419 |
| linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients. | coronary artery disease is an inflammatory disorder characterized by narrowing of coronary arteries due to atherosclerotic plaque formation. to date, the accumulated epidemiological evidence supports an association between oral bacterial diseases and coronary artery disease, but has failed to prove a causal link between the two. due to the recent surge in microbial identification and analyses techniques, a number of bacteria have been independently found in atherosclerotic plaque samples from co ... | 2016 | 28649401 |
| in vitro effects of polyphosphate against prevotella intermedia in planktonic phase and biofilm. | polyphosphate (polyp) has gained a wide interest in the food industry due to its potential as a decontaminating agent. in this study, we examined the effect of sodium tripolyphosphate (polyp3; na5p3o10) against planktonic and biofilm cells of prevotella intermedia, a major oral pathogen. the mic of polyp3 against p. intermedia atcc 49046 determined by agar dilution method was 0.075%, while 0.05% polyp3 was bactericidal against p. intermedia in time-kill analysis performed using liquid medium. a ... | 2016 | 26596937 |
| investigating oral microbiome profiles in children with cleft lip and palate for prognosis of alveolar bone grafting. | in this study, we sought to investigate the oral microbiota structure of children with cleft lip and palate (clp) and explore the pre-operative oral bacterial composition related to the prognosis of alveolar bone grafting. in total, 28 patients (19 boys, 9 girls) with clp who were scheduled to undergo alveolar bone grafting for the first time were recruited. according to the clinical examination of operative sites at the third month after the operation, the individuals were divided into a non-in ... | 2016 | 27191390 |
| assessing the use of quantitative light-induced fluorescence-digital as a clinical plaque assessment. | the aims of this study were to compare the relationship between red fluorescent plaque (rf plaque) area by quantitative light-induced fluorescence-digital (qlf-d) and disclosed plaque area by two-tone disclosure, and to assess the bacterial composition of the rf plaque by real time-pcr. | 2016 | 26691322 |
| genistein suppresses prevotella intermedia lipopolysaccharide-induced inflammatory response in macrophages and attenuates alveolar bone loss in ligature-induced periodontitis. | genistein is a major isoflavone subclass of flavonoids found in soybean and a potent tyrosine kinase inhibitor. the present study aimed to assess the effect of genistein on the production of proinflammatory mediators in murine macrophages stimulated with lipopolysaccharide (lps) isolated from prevotella intermedia, a pathogen associated with different forms of periodontal disease, and to evaluate its possible influence on alveolar bone loss in ligature-induced periodontitis using micro-computed ... | 2016 | 26655950 |
| the complete genome sequencing of prevotella intermedia strain oma14 and a subsequent fine-scale, intra-species genomic comparison reveal an unusual amplification of conjugative and mobile transposons and identify a novel prevotella-lineage-specific repeat. | prevotella intermedia is a pathogenic bacterium involved in periodontal diseases. here, we present the complete genome sequence of a clinical strain, oma14, of this bacterium along with the results of comparative genome analysis with strain 17 of the same species whose genome has also been sequenced, but not fully analysed yet. the genomes of both strains consist of two circular chromosomes: the larger chromosomes are similar in size and exhibit a high overall linearity of gene organizations, wh ... | 2016 | 26645327 |
| human dental stem cells suppress pmn activity after infection with the periodontopathogens prevotella intermedia and tannerella forsythia. | periodontitis is characterized by inflammation associated with the colonization of different oral pathogens. we here aimed to investigate how bacteria and host cells shape their environment in order to limit inflammation and tissue damage in the presence of the pathogen. human dental follicle stem cells (hdfscs) were co-cultured with gram-negative p. intermedia and t. forsythia and were quantified for adherence and internalization as well as migration and interleukin secretion. to delineate hdfs ... | 2016 | 27974831 |
| a preliminary study of the effects of ph upon fluorescence in suspensions of prevotella intermedia. | the quantification of fluorescence in dental plaque is currently being developed as a diagnostic tool to help inform and improve oral health. the oral anaerobe prevotella intermedia exhibits red fluorescence due to the accumulation of porphyrins. ph affects the fluorescence of abiotic preparations of porphyrins caused by changes in speciation between monomers, higher aggregates and dimers, but this phenomenon has not been demonstrated in bacteria. fluorescence spectra were obtained from suspensi ... | 2016 | 27441707 |
| microbiologic findings in relation to risk assessment for periodontal disease: a cross-sectional study. | in this study, an association between a computerized risk calculator and microbiologic testing is examined in patients with periodontitis. | 2016 | 26291297 |
| lethal photosensitisation of prevotellaceae under anaerobic conditions by their endogenous porphyrins. | oxygen is generally considered essential for lethal photosensitisation by photodynamic processes. the oral anaerobes, prevotella intermedia and p. nigrescens are known to be photosensitive, but are also extremely sensitive to the cytotoxic effects of oxygen. | 2016 | 26216344 |
| [gender-related marker pathogens of periodontal disease in chronic periodontitis]. | by using qpcr system, women as well as men were found to have an equal periodontal pathogen colonization. however, the women are subjected to have a higher risk of chronic periodontitis onsets. women with the chronic periodontitis usually expose an evident hypercolonization with a single pathogen. p. gingivalis is the most prevalent causative agent of the chronic periodontitis in women but not in men. in health as well as in the chronic periodontitis a complex of periodontal pathogens forms such ... | 2016 | 27367192 |
| association between maternal periodontitis and preterm and/or low birth weight infants in normal pregnancies. | to relate the periodontal condition with the presence of periodontal bacteria in pregnant that had babies with preterm delivery or/and low weight at birth (ptlbw). | 2016 | 25394610 |
| microbiological effects and recolonization patterns after adjunctive subgingival debridement with er:yag laser. | the objective of this study was to assess the microbiological effects and recolonization patterns after non-surgical periodontal treatment protocol based on the adjunctive use of erbium-doped yttrium aluminium garnet (er:yag) laser. | 2016 | 26419675 |
| in vitro resistance testing of porphyromonas gingivalis, prevotella intermedia, and tannerella forsythia to triclosan. | to determine the sensitivity of porphyromonas gingivalis, prevotella intermedia, and tannerella forsythia to triclosan, and determine if these bacteria develop resistance to triclosan upon prolonged exposure. | 2016 | 27340161 |
| porphyromonas gingivalis and epstein-barr virus are associated with increased levels of visfatin in gingival crevicular fluid. | there is little clinical information on the relationship between periodontopathogens and visfatin. the purpose of this study is to determine visfatin levels in the gingival crevicular fluid (gcf) of healthy individuals and patients with periodontitis and to investigate the possible relationship between this adipokine and the presence and levels of porphyromonas gingivalis, prevotella intermedia, prevotella nigrescense, and epstein-barr virus (ebv). | 2016 | 26561994 |
| combinations of bacterial species associated with symptomatic endodontic infections in a chinese population. | to use microarrays to detect 11 selected bacteria in infected root canals, revealing bacterial combinations that are associated with clinical symptoms and signs of primary endodontic infections in a chinese population. | 2016 | 25565631 |
| propolis, a hope for the future in treating resistant periodontal pathogens. | periodontitis is one of the most common causes of tooth loss worldwide. recently, special attention has been paid to natural medication for its treatment. for this purpose, propolis (bee glue) activity has also been investigated. its antibacterial properties are mainly attributed to flavonones pinocembrin, flavonols galangin and to the caffeic acid phenethyl ester. this study is aimed at evaluating the antimicrobial effects of propolis from pakistan on 35 clinical isolates of pigmented anaerobic ... | 2016 | 27563508 |
| [noma in a 4 year-old girl: a case report from chad]. | this case report describes a 4-year-old girl in chad with noma, also called cancrum oris. this acute gangrenous stomatitis has a combined morbidity-mortality rate that can reach 70%. it occurs worldwide but is most common in sub-saharan africa in children aged 2 to 16 years. its pathogenesis is uncertain, but several bacteria including fusobacterium necrophorum, prevotella intermedia and pseudomonas aeruginosa may be responsible for the development of noma, which develops over the oral lesions t ... | 2016 | 24736219 |
| 24-hour evaluation of dental plaque bacteria and halitosis after consumption of a single placebo or dental treat by dogs. | objective to determine whether consumption of a single dental treat with specific mechanical properties and active ingredients would provide a 24-hour effect on dental plaque bacteria and halitosis in dogs. animals 10 dogs of various breeds from a privately owned colony that had received routine dental scaling and polishing 4 weeks before the study began. procedures dogs were randomly assigned to receive 1 placebo or dental treat first. a 4-week washout period was provided, and then dogs receive ... | 2016 | 27227499 |
| in vitro evaluation of planktonic growth on experimental cement-retained titanium surfaces. | background the purpose of this study was to compare the effects of selected cements, or their combination with titanium, on the growth of two periodontopathic bacteria: prevotella intermedia (pi) and fusobacterium nucleatum (fn). material and methods this study was comprised of several experimental groups: 1) dental luting cements (glass ionomer cement, methacrylate-based resin cement, zinc-oxide eugenol cement, eugenol-free zinc oxide cement; 2) titanium discs; and 3) titanium combination cemen ... | 2016 | 27058704 |
| symptoms of periodontitis and antibody responses to porphyromonas gingivalis in juvenile idiopathic arthritis. | the association between rheumatoid arthritis (ra) and periodontitis is well established. some children with juvenile idiopathic arthritis (jia) phenotypically resemble adults with ra, characterized by the presence of anti-cyclic citrullinated peptide (ccp) antibodies. we sought to investigate an association between ccp-positive jia and symptoms of periodontitis and antibodies to oral microbiota. | 2016 | 26861944 |
| consequences of orthodontic treatment in malocclusion patients: clinical and microbial effects in adults and children. | malocclusion is a common disease of oral and maxillofacial region. the study was aimed to investigate levels changes of periodontal pathogens in malocclusion patients before, during and after orthodontic treatments, and to confirm the difference between adults and children. | 2016 | 27793138 |
| light activated antimicrobial agents can inactivate oral malodour causing bacteria. | oral malodour is a common condition which affects a large proportion of the population, resulting in social, emotional and psychological stress. certain oral bacteria form a coating called a biofilm on the tongue dorsum and degrade organic compounds releasing volatile sulfur compounds that are malodourous. current chemical treatments for oral malodour such as mouthwashes containing chlorhexidine or essential oils, are not sufficiently effective at reducing the bacterial load on the tongue. one p ... | 2016 | 27753430 |
| bacteria prevalence in a large italian population sample: a clinical and microbiological study. | the present study detects those bacterial species which are more strongly related to bleeding on probing, suppuration and smoking in periodontal-affected patients. nine hundred and fifty-one patients with periodontal diseases were admitted to the department of periodontology and implantology, dental school of bologna university where they underwent microbiological tests for six periodontal pathogens (actinomyces actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, treponema de ... | 2016 | 27469569 |
| impact of implant-abutment connection on osteoimmunological and microbiological parameters in short implants: a randomized controlled clinical trial. | the study aimed to determine the levels of soluble receptor activator of nuclear factor-кb ligand (srankl) and osteoprotegerin (opg) as well as their relative calculated ratio in peri-implant crevicular fluid (picf) obtained around two different types of implant-abutment connection on short implants following a 12-month monitoring period. moreover, the levels of a number of oral bacterial species were investigated in the corresponding submucosal biofilm samples. | 2016 | 27469171 |
| immunohistochemical analysis of the gingiva with periodontitis of type i plasminogen deficiency compared to gingiva with gingivitis and periodontitis and healthy gingiva. | type i plasminogen deficiency (plgdef) is an uncommon chronic inflammation of mucous membranes. gingival enlargements usually proceed with progressive periodontal destruction and tooth-loss. plasmin(ogen)-independent enzymatic mechanisms for fibrin clearance have already been discussed in the literature. our primary objective was to verify, immunohistochemically, the occurrence of different enzymatic factors involved in tissue breakdown of inflamed compared to healthy gingiva. secondly, we tried ... | 2016 | 27552374 |
| first cultivation of health-associated tannerella sp. hot-286 (bu063). | despite significant advances in recent years in culture-independent molecular microbiology methods, the detailed study of individual bacterial species still relies on having pure cultures in the laboratory. yet, more than a third of the approximately 700 bacterial taxa found in the human oral cavity are as yet uncultivated in vitro. one such taxon, tannerella sp. hot-286 (phylotype bu063), is the focus of much interest since it is associated with periodontal health, while tannerella forsythia, i ... | 2016 | 27193146 |
| association between serum antibodies to periodontal bacteria and rheumatoid factor in the third national health and nutrition examination survey. | alterations in the microbiome, including the periodontal microbiome, may be a risk factor for rheumatoid arthritis (ra). most studies that have analyzed this association are relatively small, focus primarily on a single periodontal pathogen (porphyromonas gingivalis), and are not population based. this study was undertaken to investigate the association between elevated serum levels of igg antibodies to 19 periodontal species and the prevalence of rheumatoid factor (rf) in a large nationally rep ... | 2016 | 27110949 |
| the current weight of evidence of the microbiologic profile associated with peri-implantitis: a systematic review. | there is currently no consensus regarding microorganisms that may be considered true peri-implant pathogens. therefore, the aim of this systematic review is to determine the weight of evidence for microorganisms related to peri-implantitis based on results of association studies. | 2016 | 27420109 |
| periodontal pathogens and risk of incident cancer in postmenopausal females: the buffalo osteoperio study. | extraoral translocation of oral bacteria may contribute to associations between periodontal disease and cancer. the associations among the presence of three orange-complex periodontal pathogens (fusobacterium nucleatum, prevotella intermedia, and campylobacter rectus), two red-complex periodontal pathogens (porphyromonas gingivalis and tannerella forsythia), and cancer risk were investigated. | 2016 | 26513268 |
| microbiota at teeth and implants in partially edentulous patients. a 10-year retrospective study. | to determine the microbiota at implants and adjacent teeth 10 years after placement of implants with a sandblasted and acid-etched surface. | 2016 | 25827437 |
| detection of subgingival periodontal pathogens--comparison of two sampling strategies. | the aim of the study is to compare detection frequency of periodontal pathogens in patients with aggressive/severe chronic periodontitis using pooled plaque samples from the deepest pockets per quadrant/per sextant. | 2016 | 26193958 |
| anti-microbial efficacy of soursop leaf extract (annona muricata) on oral pathogens: an in-vitro study. | annona muricata also called as soursop is a, flowering evergreen tree native to mexico, cuba, central america and parts of india. the miracle tree as it is widely known as a natural cancer killer that is 10,000 times stronger than chemotherapy. based on these miraculous claims, the leaves of these plants were used as an extract at varying concentrations as an antibacterial agent against oral pathogens. | 2016 | 28050493 |
| estimation of antimicrobial properties of aqueous and alcoholic extracts of salvadora persica (miswak) on oral microbial pathogens - an invitro study. | twigs of salvadora persica (miswak) plant are being used as a means of oral hygiene since ages for brushing teeth. though clinical research and trials have shown promising results on effectiveness of miswak, but some reports are conflicting. | 2016 | 27790459 |
| selective photoantisepsis. | selective killing of pathogens by laser is possible due to the difference in absorption of photon energy by pathogens and host tissues. the optical properties of pathogenic microorganisms are used along with the known optical properties of soft tissues in calculations of the laser-induced thermal response of pathogen colonies embedded in a tissue model. the objective is to define the laser parameters that optimize pathogen destruction and depth of the bactericidal effect. | 2016 | 27726169 |
| the black bug myth: selective photodestruction of pigmented pathogens. | it is commonly believed that pigmented pathogens are selectively targeted by dental lasers. to test this notion optical diffuse reflection spectroscopy (drs) was used to obtain absorption spectra for the periodontal pathogens, porphyromonas gingivalis (pg) and prevotella intermedia (pi). | 2016 | 27479737 |
| periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri-implant tissues. | to compare the prevalence and levels of six bacterial pathogens within the subgingival/submucosal microbiota at teeth versus implants with various clinical conditions. | 2016 | 25399962 |
| efficacy of photodynamic therapy and lasers as an adjunct to scaling and root planing in the treatment of aggressive periodontitis - a clinical and microbiologic short term study. | aggressive periodontitis comprises a group of rare, severe, rapidly progressive form of periodontitis. conventional treatment includes mechanical debridement augmented with adjunctive antimicrobial therapy. development of antibiotic resistance has led to use of lasers. photodynamic therapy (pdt) is a novel non-invasive therapeutic approach with increased site and pathogen specificity. this study compares pdt and lasers as an adjunct to conventional scaling in the treatment of patients with aggre ... | 2016 | 27042576 |
| antimicrobial effects of commensal oral species are regulated by environmental factors. | the objectives of this study are to identify oral commensal species which can inhibit the growth of the main periodontopathogens, to determine the antimicrobial substances involved in these inhibitory activities and to evaluate the influence of environmental factors on the magnitude of these inhibitions. | 2016 | 26875613 |
| inverse association of plasma igg antibody to aggregatibacter actinomycetemcomitans and high c-reactive protein levels in patients with metabolic syndrome and periodontitis. | the association between clinically diagnosed periodontitis, a common chronic oral infection, and metabolic syndrome has been previously reported. the aim of this study was to investigate the association of plasma igg levels against aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, and prevotella intermedia, c-reactive protein, and periodontal status with metabolic syndrome. plasma igg levels and c-reactive protein were measured by enzyme-linked immunosorbent assay, and salivary le ... | 2016 | 26871443 |