Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| synanthropic mammals as potential hosts of tick-borne pathogens in panama. | synanthropic wild mammals can be important hosts for many vector-borne zoonotic pathogens. the aim of this study was determine the exposure of synanthropic mammals to two types of tick-borne pathogens in panama, spotted fever group rickettsia (sfgr) and borrelia relapsing fever (rf) spirochetes. one hundred and thirty-one wild mammals were evaluated, including two gray foxes, two crab-eating foxes (from zoos), four coyotes, 62 opossum and 63 spiny rats captured close to rural towns. to evaluate ... | 2017 | 28060928 |
| health survey of free-ranging raccoons (procyon lotor) in central park, new york, new york, usa: implications for human and domestic animal health. | we conducted health assessments on 113 free-ranging raccoons ( procyon lotor ) in central park, new york city, us, in february 2010, september 2010, and november 2011 in conjunction with a trap-vaccinate-release program to control a raccoon rabies epizootic. five individuals were sampled at two time points for 118 raccoon examinations in total. we tested 13 of 13 and 8 of 13 euthanized raccoons for rabies and canine distemper virus (cdv), respectively, by antigen testing on brain tissue; all wer ... | 2017 | 28135131 |
| multiple-host pathogens in domestic hunting dogs in nicaragua's bosawás biosphere reserve. | nicaragua's bosawás biosphere reserve is a vast forested area inhabited largely by indigenous mayangna and miskitu people. most bosawás residents rely on subsistence hunting and swidden agriculture, and hunting dogs are important for finding and securing wild game. we investigated the health of hunting dogs in three communities differing in location, size, and economy. dogs in all communities were nutritionally compromised and experienced a heavy burden of disease. seroprevalence of canine diste ... | 2017 | 28012903 |
| association of the occurrence of brazilian spotted fever and atlantic rain forest fragmentation in the são paulo metropolitan region, brazil. | brazilian spotted fever (bsf) is a zoonotic disease caused by the bacterium rickettsia rickettsii. in the são paulo metropolitan region (spmr) it is transmitted by amblyomma aureolatum ticks. in this region, annual lethality of the disease can reach 80% and spatial occurrence depends on environmental factors and more particularly on the presence and interaction of domestic and wild carnivores as well as the presence and characteristics of the remnant atlantic rain forest patches. this study anal ... | 2017 | 27880877 |
| evaluation of an association of alpha-cypermethrin and flufenoxuron for tick control in an area at risk of brazilian spotted fever. | brazilian spotted fever (bsf) is an endemic anthropozoonosis caused by gram-negative bacteria (rickettsia rickettsii) that is associated with the risk of human infection by ticks. in the city of americana, são paulo (sp), brazil, there were 12 cases (67% lethal) between 2004 and 2015. this study evaluated the effectiveness of control over tick infestations in an area at risk of bsf, in a field trial on an association of alpha-cypermethrin (3%) and flufenoxuron (3%) (tenopa(®)) conducted in ameri ... | 2017 | 28377149 |
| rocky mountain spotted fever in mexico: past, present, and future. | rocky mountain spotted fever, a tick-borne zoonosis caused by rickettsia rickettsii, is among the most lethal of all infectious diseases in the americas. in mexico, the disease was first described during the early 1940s by scientists who carefully documented specific environmental determinants responsible for devastating outbreaks in several communities in the states of sinaloa, sonora, durango, and coahuila. these investigators also described the pivotal roles of domesticated dogs and rhipiceph ... | 2017 | 28365226 |
| predictive factors for fatal tick-borne spotted fever in brazil. | in brazil, two pathogenic rickettsia species have been identified causing tick-borne spotted fever (sf). the aetiological agent rickettsia rickettsii causes serious illness, particularly in the south-eastern region of the country. moreover, the rickettsia sp. strain atlantic rainforest cause milder clinical manifestations in south-eastern, south and north-east regions. this study has sought to analyse predictive factors for fatal sf. a case-control study was performed using disease notification ... | 2017 | 28169507 |
| [fatal case of rickettsiosis in a toddler from southeastern mexico]. | rocky mountain spotted fever is a disease caused by rickettsia rickettsii, a bacteria transmitted by infected ticks. it is characterized by fever, exanthema, arthralgias and myalgias; but sometimes its clinical presentation is non specific. due to its similarities with other exanthematic diseases like dengue or chikungunya, rocky mountain spotted fever is not a first line diagnosis, even though countries like mexico show the ecologic and socioeconomic characteristics that favor its transmission, ... | 2017 | 28097845 |
| proteolytic cleavage of the immunodominant outer membrane protein rompa in rickettsia rickettsii. | rickettsia rickettsii, the causative agent of rocky mountain spotted fever, contains two immunodominant proteins, rompa and rompb, in the outer membrane. both rompa and rompb are conserved throughout spotted fever group rickettsiae as members of a family of autotransporter proteins. previously, it was demonstrated that rompb is proteolytically processed, with the cleavage site residing near the autotransporter domain at the carboxy-terminal end of the protein, cleaving the 168-kda precursor into ... | 2017 | 28031280 |
| microscopic and molecular identification of hemotropic mycoplasmas in south american coatis (nasua nasua). | hemoplasmas were detected in two apparently healthy captive south american coatis (nasua nasua) from southern brazil during an investigation for vector-borne pathogens. blood was subjected to packed cell volume (pcv) determination, a commercial real-time pcr panel for the detection of anaplasma spp., babesia spp., bartonella spp., hepatozoon spp., leishmania spp., mycoplasma haemofelis, 'candidatus mycoplasma turicensis', 'candidatus mycoplasma haemominutum', neorickettsia risticii, rickettsia r ... | 2017 | 28750863 |
| epidemiology of spotted fever group rickettsioses and acute undifferentiated febrile illness in villeta, colombia. | etiology of acute undifferentiated febrile syndrome (aufs) is often unknown, leading to inaccurate diagnosis and treatment. villeta town has been identified as an endemic area for spotted fever group (sfg) rickettsioses but little is known about possible amplifier hosts and other rickettsia species different from rickettsia rickettsii. besides, few studies have approached other aufs etiologies in the region. we investigated the role of dengue, leptospirosis, rickettsioses, human anaplasmosis, an ... | 2017 | 28722568 |
| comparative vertical transmission of rickettsia by dermacentor variabilis and amblyomma maculatum. | the geographical overlap of multiple rickettsia and tick species coincides with the molecular detection of a variety of rickettsial agents in what may be novel tick hosts. however, little is known concerning transmissibility of rickettsial species by various tick hosts. to examine the vertical transmission potential between select tick and rickettsial species, two sympatric species of ticks, dermacentor variabilis and amblyomma maculatum, were exposed to five different rickettsial species, inclu ... | 2017 | 28433729 |
| first report of a rickettsia asembonensis related infecting fleas in brazil. | the present study was performed in a non-endemic area for spotted fever (sf) in imperatriz microregion, state of maranhão, brazil. blood samples and ectoparasites were collected from 300 dogs of the imperatriz microregion. canine serum samples were tested individually by indirect immunofluorescence assay (ifa), using five rickettsia isolates from brazil. antibodies reactive to at least one of the five species of rickettsia were detected in 1.6% of the dogs (5/300). these sera were considered rea ... | 2017 | 28427962 |
| anaplasma, ehrlichia and rickettsia species infections in cats: european guidelines from the abcd on prevention and management | anaplasma species, ehrlichia species and rickettsia species are vector-borne pathogens infecting a wide variety of mammals, but causing disease in very few of them. infection in cats: anaplasma phagocytophilum is the most important feline pathogen among these rickettsial organisms, and coinfections are possible. little information is available on the pathogenesis of these agents in cats. clinical signs are usually reported soon after tick infestation. they are mostly non-specific, consisting of ... | 2017 | 28438088 |
| seroepidemiology of spotted fever rickettsiosis in uttar pradesh: a prospective study. | spotted fever rickettsiosis (sfr), an acute febrile illness caused by rickettsia rickettsii, r. conorii and r. akari which is associated with considerable morbidity and mortality. sfr is one of the most covert emerging infections of the present time which is prevalent in various parts of india as shown by the increase in the number of clinically diagnosed patients in various states except uttar pradesh. | 2017 | 28764157 |
| ehrlichia canis and rickettsia spp. in dogs from urban areas in paraiba state, northeastern brazil. | the aims of our study was to identify ehrlichia canis and antibodies against rickettsia spp. belonging to the spotted fever group (sfg) in dogs sampled from paraiba state, northeastern brazil. blood and serum samples collected by convenience from dogs in urban areas of five municipalities were analyzed by real-time pcr for the detection of e. canis dna and by immunofluorescence assay test (ifat) for the identification of antibodies against rickettsia rickettsii, r. felis, r. parkeri, r. amblyomm ... | 2017 | 28658415 |
| rickettsia rickettsii infecting rhipicephalus sanguineus sensu lato (latreille 1806), in high altitude atlantic forest fragments, ceara state, brazil. | in brazil, spotted fever (sf) is caused by rickettsia rickettsii and rickettsia parkeri strain atlantic forest. in recent years, several human cases of a milder sf have been reported from the maciço de baturité region of ceará state. previous studies in this region found r. parkeri strain atlantic forest to be present in rhipicephalus sanguineus sensu lato and amblyomma ovale ticks. the present study isolated and identified the rickettsia spp. present in this new endemic area in brazil. in march ... | 2017 | 28535905 |
| evaluation of changes to the rickettsia rickettsii transcriptome during mammalian infection. | the lifecycle of rickettsia rickettsii includes infection of both mammalian and arthropod hosts, with each environment presenting distinct challenges to survival. as such, these pathogens likely have distinctive transcriptional strategies for infection of each host. herein, we report the utilization of next generation sequencing (rnaseq) and bioinformatic analysis techniques to examine the global transcriptional profile of r. rickettsii within an infected animal, and to compare that data to tran ... | 2017 | 28832688 |
| efficacy of sarolaner (simparic™) against induced infestations of amblyomma cajennense on dogs. | amblyomma cajennense is the main vector of rickettsia rickettsii which causes brazilian spotted fever. this adult tick preferably infests horses and capybaras, but has low host specificity during its immature stages, thus posing a threat to humans and dogs. in this study, the efficacy of sarolaner (simparic™/simparica®, zoetis) when administered once orally to dogs at 2 mg/kg was evaluated against induced infestations of a. cajennense nymphs for up to 35 days after treatment. | 2017 | 28814323 |
| rocky mountain spotted fever and pregnancy: four cases from sonora, mexico. | we present a series of four pregnant women with rocky mountain spotted fever (rmsf) that occurred in sonora, mexico, during 2015-2016. confirmatory diagnoses were made by polymerase chain reaction or serological reactivity to antigens of rickettsia rickettsii by using an indirect immunofluorescence antibody assay. each patient presented with fever and petechial rash and was treated successfully with doxycycline. each of the women and one full-term infant delivered at 36 weeks gestation survived ... | 2017 | 28722584 |
| microrna signature of human microvascular endothelium infected with rickettsia rickettsii. | micrornas (mirnas) mediate gene silencing by destabilization and/or translational repression of target mrna. infection of human microvascular endothelial cells as primary targets of rickettsiarickettsii, the etiologic agent of rocky mountain spotted fever, triggers host responses appertaining to alterations in cellular gene expression. microarray-based profiling of endothelial cells infected with r.rickettsii for 3 or 24 h revealed differential expression of 33 mirnas, of which mirnas129-5p, 200 ... | 2017 | 28698491 |
| transmission dynamics and control of rickettsia rickettsii in populations of hydrochoerus hydrochaeris and amblyomma sculptum. | brazilian spotted fever (bsf), caused by the bacterium rickettsia rickettsii, is the tick-borne disease that generates the largest number of human deaths in the world. in brazil, the current increase of bsf human cases has been associated with the presence and expansion of capybaras hydrochoerus hydrochaeris, which act as primary hosts for the tick amblyomma sculptum, vector of the r. rickettsii in this area. | 2017 | 28582429 |
| the distinct transcriptional response of the midgut of amblyomma sculptum and amblyomma aureolatum ticks to rickettsia rickettsii correlates to their differences in susceptibility to infection. | rickettsia rickettsii is a tick-borne obligate intracellular bacterium that causes rocky mountain spotted fever (rmsf). in brazil, two species of ticks in the genus amblyomma, a. sculptum and a. aureolatum, are incriminated as vectors of this bacterium. importantly, these two species present remarkable differences in susceptibility to r. rickettsii infection, where a. aureolatum is more susceptible than a. sculptum. in the current study, a. aureolatum and a. sculptum ticks were fed on suitable h ... | 2017 | 28503490 |
| vector competence of amblyomma americanum (acari: ixodidae) for rickettsia rickettsii. | rickettsia rickettsii - the etiologic agent of rocky mountain spotted fever (rmsf) - is widely spread across the americas. in the us, dermacentor spp. ticks are identified as primary vectors of r. rickettsii and rhipicephalus sanguineus s.l. has been implicated in transmission of this pathogen in several locations in the southwest. conversely, ticks of the genus amblyomma are recognized vectors of rmsf in central and south america, but not in the us. a. americanum is one of the most aggressive h ... | 2017 | 28433728 |
| first report of mild brazilian spotted fever associated to arthritis. | we describe the first brazilian case of mild rickettsiosis, complicated by knee monoarthritis, in young adult bitten by a tick on his left leg in camburi zone, located in são sebastião municipality, southern coastal region of the state of são paulo, in the atlantic rainforest region, brazil. the patient developed inoculation eschar at the tick bite site associated with enlarged lymph nodes in the left groin, fever, polyarthralgia, headache and macular rash. twenty days after tick bite episode, h ... | 2017 | 25054603 |
| probability of occurrence of the brazilian spotted fever in northeast of paraná state, brazil. | brazilian spotted fever (bsf) is a fatal zoonosis because of the difficulties in its early diagnosis and treatment. occurrences of bsf in the northeast of the state of paraná prompted investigation of areas at risk of this rickettsiosis in the municipalities of japira, jaboti, pinhalão and tomazina. to determine the areas at risk, 592 serum samples from dogs and 230 from equids were analyzed by means of the indirect immunofluorescence assay (ifa) for rickettsia rickettsii and r. parkeri . in add ... | 2016 | 27925056 |
| human infections by multiple spotted fever group rickettsiae in tennessee. | rocky mountain spotted fever is the most common tick-borne disease in tennessee. however, rickettsia rickettsii has rarely been isolated from endemic ticks, suggesting rickettsioses may be caused by other species. a total of 56 human serum samples that were serologically positive for exposure to rickettsia were obtained from commercial laboratories in 2010 and 2011. in addition, 20 paired sera from patients with encephalitis and positive rickettsia serology were obtained from the tennessee unexp ... | 2016 | 27022147 |
| infection of amblyomma ovale with rickettsia species atlantic rainforest in serra do mar, são paulo state, brazil. | rickettsia rickettsii and rickettsia sp. strain atlantic rainforest, that is considered to represent a genetic variant of rickettsia parkeri, are confirmed as being capable of infecting humans in brazil. this study reports the detection and characterization, by pcr and nucleotide sequencing, of rickettsia sp. strain atlantic rain forest in amblyomma ovale parasitizing a human, in ticks infesting dogs and in free-living ticks collected from the environment where the human infestation was recorded ... | 2016 | 27430967 |
| comparative value of blood and skin samples for diagnosis of spotted fever group rickettsial infection in model animals. | the definitive diagnosis of spotted fever group (sfg) rickettsioses in humans is challenging due to the retrospective nature and cross reactivity of the serological methods and the absence of reliable and consistent samples for molecular diagnostics. existing data indicate the transient character of bacteremia in experimentally infected animals. the ability of arthropod vectors to acquire rickettsial infection from the laboratory animals in the absence of systemic infection and known tropism of ... | 2016 | 27282078 |
| national surveillance of spotted fever group rickettsioses in the united states, 2008-2012. | spotted fever group (sfg) rickettsioses are notifiable conditions in the united states caused by the highly pathogenic rickettsia rickettsii and less pathogenic rickettsial species such as rickettsia parkeri and rickettsia sp. 364d. surveillance data from 2008 to 2012 for sfg rickettsioses are summarized. incidence increased from 1.7 cases per million person-years (py) in 2000 to 14.3 cases per million py in 2012. during 2008-2012, cases of sfg rickettsiosis were more frequently reported among m ... | 2016 | 26324732 |
| notes from the field: community-based prevention of rocky mountain spotted fever - sonora, mexico, 2016. | rocky mountain spotted fever (rmsf), a life-threatening tickborne zoonosis caused by rickettsia rickettsii, is a reemerging disease in mexico (1,2). r. rickettsii is an intracellular bacterium that infects vascular endothelium and can cause multisystem organ failure and death in the absence of timely administration of a tetracycline-class antibiotic, typically doxycycline. epidemic rmsf, as described in parts of arizona and mexico, is associated with massive local infestations of the brown dog t ... | 2016 | 27880753 |
| a fatal case of brazilian spotted fever in a non-endemic area in brazil: the importance of having health professionals who understand the disease and its areas of transmission. | brazilian spotted fever (bsf) is caused by the bacterium rickettsia rickettsii. because of its high case-fatality rate and apparent increase in areas of transmission, it is considered to be the rickettsial illness of primary public health interest. cases of this disease have historically occurred in southeastern brazil. this article reports the first fatal case of bsf in southern brazil. this case high lights the importance of bsf to be considered as a differential diagnosis for acute hemorrhagi ... | 2016 | 27812666 |
| vectorial competence of amblyomma tonelliae to transmit rickettsia rickettsii. | the aim of this work was to test the vectorial competence of amblyomma tonelliae (ixodida: ixodidae) to transmit rickettsia rickettsii (rickettsiales: rickettsiaceae), the agent of rocky mountain spotted fever (rmsf). all parasitic stages of a. tonelliae were exposed to r. rickettsii by allowing each stage to feed on hosts inoculated with this pathogen. thereafter, ticks were fed on uninfected hosts. all stages of a. tonelliae were able to acquire the r. rickettsii infection and maintain it by t ... | 2016 | 27677425 |
| [severe spotted fever by rickettsia rickettsii, in tourist in the argentine northwest]. | on the fifth day after leaving the parque nacional el rey, province of salta, argentina, where she made rural tourism, a woman of italian origin, aged 47, developed an acute fever followed by a petechial and purpuric rash that progressed rapidly to multiorgan failure. she died on the sixth day after hospitalization. there were references to tick bites and a skin lesion similar to tache noire was found. the autopsy showed generalized vasculitis, ascites, pulmonary edema, acute tubular necrosis an ... | 2016 | 27723622 |
| high prevalence of "candidatus rickettsia amblyommii" in amblyomma ticks from a spotted fever endemic region in north argentina. | ticks from an endemic spotted fever region in argentina were analysed by pcr for spotted fever group rickettsiae. dna of "candidatus rickettsia amblyommii" was found in 21.3% of amblyomma hadanii and in 44.0% of a. neumanni. amblyomma sculptum (formerly a. cajennense) and haemaphysalis juxtakochi were negative for rickettsial dna. dna of rickettsia rickettsii, the etiological agent of the clinical cases reported within the studied region was not detected in the analysed sample. | 2016 | 27260814 |
| characterization of genetic variability and population structure of the tick amblyomma aureolatum (acari: ixodidae). | the hard tick amblyomma aureolatum (pallas) is a vector of the bacterium rickettsia rickettsii, the etiologic agent of brazilian spotted fever (bsf) in parts of brazil. despite its wide distribution in southeastern south america and its public health importance, there is no information about genetic variation of this species that might help to understand the epidemiology of bsf. using data from eight microsatellite markers and ticks from six localities, we used a population genetics approach to ... | 2016 | 27230435 |
| distribution of spotted fever group rickettsiae in hard ticks (ixodida: ixodidae) from panamanian urban and rural environments (2007-2013). | tick-borne rickettsiosis is an important emerging disease in panama; to date, there have been 12 confirmed cases, including eight fatalities. to evaluate the distribution of rickettsiae in panamanian ticks, we collected questing and on-host ticks in urban and rural towns in elevations varying between 0 and 2300 m. a total of 63 sites (13 urban and 50 rural towns) were used to develop models of spatial distributions. we found the following tick species: rhipicephalus sanguineus s.l. (present in 5 ... | 2016 | 27068930 |
| amblyomma mixtum koch, 1844 (acari: ixodidae): first record confirmation in colombia using morphological and molecular analyses. | up to some years ago, the taxon amblyomma cajennense represented a single tick species in the new world, from southern united states to northern argentina. recent studies, based on genetic, reproductive and morphological data reorganized this taxon into a complex of the following 6 valid species: a. cajennense sensu stricto, amblyomma mixtum, amblyomma sculptum, amblyomma interandinum, amblyomma tonelliae, and amblyomma patinoi. according to this classification, the a. cajennense complex is curr ... | 2016 | 27062448 |
| first report of rickettsia identical to r. slovaca in colony-originated d. variabilis in the united states: detection, laboratory animal model, and vector competence of ticks. | ticks of the genus dermacentor are known vectors of rickettsial pathogens in both the old world and new world. in north america, dermacentor variabilis and d. andersoni are vectors of rickettsia rickettsii, while in europe, d. marginatus and d. reticulatus transmit r. slovaca and r. raoultii, respectively. neither the presence of r. slovaca in the americas nor the ability of american tick species to maintain this pathogen have been reported. here we describe detection of rickettsia genetically i ... | 2016 | 26808054 |
| estimation of rickettsia rickettsii copy number in the blood of patients with rocky mountain spotted fever suggests cyclic diurnal trends in bacteraemia. | 2016 | 26724989 | |
| effect of rickettsia rickettsii (rickettsiales: rickettsiaceae) infection on the biological parameters and survival of its tick vector-dermacentor variabilis (acari: ixodidae). | rocky mountain spotted fever, caused by rickettsia rickettsii, is a potentially fatal tick-borne disease spread from north america to argentina. the major vectors of r. rickettsii in the united states are dermacentor andersoni stiles and dermacentor variabilis (say). it is generally believed that vector ticks serve as major reservoirs of r. rickettsii in nature; however, the ability of ticks to support the indefinite perpetuation of r. rickettsii has been challenged by reports of deleterious eff ... | 2016 | 26494822 |
| physiological characterization of the hematophagy of ornithodoros rostratus (acari: argasidae) on live hosts. | ornithodoros rostratus is an argasid tick and its importance is based on its hematophagy and the resulting transmission of pathogens such as rickettsia rickettsii and coxiella burnetii to its vertebrate hosts. in the face of a lack of physiological studies related to hematophagy in argasid ticks, this paper aims to identify and characterize the events that occur throughout the feeding by o. rostratus on live hosts. electrical signals and alterations on the feeding site were monitored using intra ... | 2016 | 27625415 |
| prevalence of rickettsia species in dermacentor variabilis ticks from ontario, canada. | relatively little is known about the prevalence of rickettsial species in dermacentor ticks in eastern canada. in this study, dermacentor ticks from the province of ontario, canada, were tested for the presence of spotted fever group rickettsial (sfgr) species, coxiella burnetii and francisella tularensis. rickettsia rickettsii was not detected in any ticks tested, but r. montanensis was detected at a prevalence of 2.2% in d. variabilis (17/778). two other sfgr species, r. parkeri and candidatus ... | 2016 | 27318438 |
| antibodies for rickettsia spp. in patients with negative serology for dengue virus, leptospirosis, and meningococcal disease in municipalities of são paulo state, brazil. | brazilian spotted fever is an infectious disease with a high mortality rate if not treated early. differential diagnosis is difficult, as the first clinical signs are non-specific and can be confused with other diseases. the aim of the study was to investigate evidence of infection with rickettsia rickettsii and rickettsia parkeri in negative sera samples, collected in 2014, from patients with suspected leptospirosis, dengue fever, and meningococcal disease in atibaia and bragança paulista munic ... | 2016 | 27812650 |
| vector-borne infections in tornado-displaced and owner-relinquished dogs in oklahoma, usa. | to determine the prevalence of infection with vector-borne agents in a cross-section of dogs from oklahoma, where canine vector-borne diseases are common, blood samples were evaluated through serology and molecular analysis. antibodies reactive to ehrlichia spp., rickettsia rickettsii, r. montanensis, and "r. amblyommii" were detected in 10.5% (11/105), 74.3% (78/105), 58.1% (61/105), and 55.2% (58/105) of dogs, respectively. presence of spotted fever group rickettsia spp. dna was identified in ... | 2016 | 27119261 |
| detection of rickettsiae in fleas and ticks from areas of costa rica with history of spotted fever group rickettsioses. | outbreaks of spotted fevers have been reported in costa rica since the 1950s, although vectors responsible for transmission to humans have not been directly identified. in this study, species of rickettsia were detected in ectoparasites from costa rica, mostly from five study sites where cases of spotted fevers have been reported. ticks and fleas were collected using drag cloths or directly from domestic and wild animals and pooled according to species, host, and location. pools were analyzed in ... | 2016 | 27592065 |
| exposure of dogs to spotted fever group rickettsiae in urban sites associated with human rickettsioses in costa rica. | the zoonotic transmission cycles of rickettsia rickettsii and other spotted fever group (sfg) rickettsiae in latin america have usually been associated with rural or sylvatic environments, although domestic dogs can be implicated in more populated settings. in this study, exposure of dogs to sfg rickettsiae in the greater metropolitan area of costa rica was investigated. dogs from sites associated with human cases and from dog shelters were evaluated by indirect immunofluorescence assay (ifa) us ... | 2016 | 26995323 |
| serological evidence of exposure to tick-borne agents in opossums (didelphis spp.) in the state of são paulo, brazil. | this work involved a serological investigation of tick-borne pathogens in opossums in eight municipalities of the state of são paulo, brazil. serum samples from 109 opossums (91 didelphis aurita and 18 didelphis albiventris) were tested to detect antibodies to rickettsia rickettsii (taiaçu strain, 1:64 cut-off) and ehrlichia canis (são paulo strain, 1:40 cut-off), by indirect immunofluorescence assay (ifa); and against borrelia burgdorferi (strain g39/40) by enzyme-linked immunosorbent assay (el ... | 2016 | 27276663 |
| incident tick-borne infections in a cohort of north carolina outdoor workers. | tick-borne diseases cause substantial morbidity throughout the united states, and north carolina has a high incidence of spotted fever rickettsioses and ehrlichiosis, with sporadic cases of lyme disease. the occupational risk of tick-borne infections among outdoor workers is high, particularly those working on publicly managed lands. this study identified incident tick-borne infections and examined seroconversion risk factors among a cohort of north carolina outdoor workers. workers from the nor ... | 2016 | 27008102 |
| rickettsia vini n. sp. (rickettsiaceae) infecting the tick ixodes arboricola (acari: ixodidae). | recently, a new rickettsia named 'candidatus rickettsia vini' belonging to the spotted fever group has been molecularly detected in ixodes arboricola ticks in spain, the czech republic, slovakia and turkey, with prevalence reaching up to 100 %. the aim of this study was to isolate this rickettsia in pure culture, and to describe it as a new rickettsia species. | 2016 | 27565956 |
| rhipicephalus sanguineus (acari: ixodidae) biting a human being in portoalegre city, rio grande do sul, brazil. | we report the finding of a female brown dog tick, rhipicephalus sanguineus (acari: ixodidae) on the scalp of a male patient inporto alegre, rio grande do sul, brazil. human parasitism by this tick is rare and has seldomly been reported in the literature, despite its recognized importance since it can act as a vector of rickettsia rickettsii, the agent of spotted fever. | 2016 | 27074329 |
| geographical distribution of amblyomma cajennense (sensu lato) ticks (parasitiformes: ixodidae) in brazil, with description of the nymph of a. cajennense (sensu stricto). | until recently, amblyomma cajennense (fabricius, 1787) was considered to represent a single tick species in the new world. recent studies have split this taxon into six species. while the a. cajennense species complex or a. cajennense (sensu lato) (s.l.) is currently represented by two species in brazil, a. cajennense (sensu stricto) (s.s.) and amblyomma sculptum berlese, 1888, their geographical distribution is poorly known. | 2016 | 27036324 |
| ticks and rickettsiae from wildlife in belize, central america. | the agents of spotted fevers in latin america are rickettsia rickettsii, r. parkeri, rickettsia sp. strain atlantic rainforest, and r. massiliae. in continental central america, r. rickettsii remains the only known pathogenic tick-borne rickettsia. in the present study, ticks were collected from wild mammals in natural areas of belize. besides providing new data of ticks from belize, we investigated rickettsial infection in some of these ticks. our results provide ticks harboring rickettsial age ... | 2016 | 26831147 |
| experimental infection of horses with rickettsia rickettsii. | rickettsia rickettsii is vectored by ticks, and some vertebrate hosts can be sources of infection to ticks during bacteremic periods. in brazil, the main vector for r. rickettsii is the tick amblyomma sculptum, a member of the a. cajennense complex. horses, in turn, are one of the major hosts for a. sculptum. in this study, horses experimentally infected with r. rickettsii were assessed for clinical changes and their capability to transmit the infection to a. sculptum ticks. | 2016 | 27624315 |
| high seroprevalence for rickettsia rickettsii in equines suggests risk of human infection in silent areas for the brazilian spotted fever. | equines play a role in the epidemiology of brazilian spotted fever (bsf) since they are a primary host for the tick amblyomma sculptum. we studied the seroprevalence for three species of rickettsia in equines in four endemic (with human cases) and in four non-endemic areas (no human cases) in the piracicaba river basin, são paulo, brazil. a serological survey of 504 equines was performed: around 63 animals were sampled in each area and tested through indirect immunofluorescence assay for r. rick ... | 2016 | 27064788 |
| differences in intracellular fate of two spotted fever group rickettsia in macrophage-like cells. | spotted fever group (sfg) rickettsiae are recognized as important agents of human tick-borne diseases worldwide, such as mediterranean spotted fever (rickettsia conorii) and rocky mountain spotted fever (rickettsia rickettsii). recent studies in several animal models have provided evidence of non-endothelial parasitism by pathogenic sfg rickettsia species, suggesting that the interaction of rickettsiae with cells other than the endothelium may play an important role in pathogenesis of rickettsia ... | 2016 | 27525249 |
| virulence genes of rickettsia rickettsii are differentially modulated by either temperature upshift or blood-feeding in tick midgut and salivary glands. | rickettsia rickettsii, the etiological agent of rocky mountain spotted fever, is transmitted to humans by ticks. during tick feeding, r. rickettsii is exposed to both temperature elevation and components of the blood meal, which have previously been associated with the reactivation of its virulence. these environmental stimuli were also reported to modulate virulence genes of r. rickettsii infecting a set of organs of adult females of its natural vector, amblyomma aureolatum. | 2016 | 27287539 |
| contributions to rickettsioses research in colombia (1917-1943), luis b. patiño camargo. | colombian physician luis benigno patiño camargo was one of the pioneers in the study of rickettsioses in south america, demonstrating for the first time in colombia the presence of rickettsia rickettsii as the etiological agent of a highly deadly exanthematic febrile syndrome in the 1930s. however, patiño-camargo performed other investigations from 1917-1943, which represent the first descriptions and scientific evidence of the presence of r. prowazekii and r. typhi in colombia. almost 60 years ... | 2016 | 27074327 |
| drug use, drug-use attitudes, and the authoritarianism-rebellion dimension. | 2016 | 5088031 | |
| [iatrogenic accident. trial of a case involving the accidental death of a blood donor at the chiba university hospital]. | 2016 | 4994305 | |
| [case of the lumbar disc herniating into the subdural space]. | 2016 | 5106825 | |
| [heteroplastic transplants with kiel bone]. | 2016 | 4912781 | |
| effect of dipyridamole on the incidence of arterial emboli after cardiac valve replacement. | 2016 | 4893436 | |
| [the hypoplastic thumb]. | 2016 | 4874597 | |
| [epidemiology of histiocytic sarcomatosis of hemopoietic tissues. clinico-statistical considerations and remarks on predisposing, premorbid and morbid conditions in 545 cases in certain regions of lazio]. | 2016 | 4861511 | |
| cross-cultural evaluation of schneider's first-rank symptoms of schizophrenia: a report from the international pilot study of schizophrenia. | 2016 | 4827800 | |
| sampling issues in family studies of schizophrenia. | 2016 | 4809929 | |
| [compulsory continuing medical education?]. | 2016 | 4778859 | |
| [editorial: asplenia]. | 2016 | 4776005 | |
| gas chromatographic-mass spectrometric studies of tricyclic compounds used in psychiatry. | 2016 | 4765105 | |
| ectrodactyly, ectodermal dysplasia, and clefting syndrome. | 2016 | 4759861 | |
| metabolism of 2,4-dichlorophenoxyacetic acid. v. identification of metabolites in soybean callus tissue cultures. | 2016 | 4736996 | |
| [classification of intersexuality]. | 2016 | 4906763 | |
| ultrastructure manifestations of g m1 and g m2 gangliosidosis in fetal tissues. | 2016 | 4701390 | |
| clinical evaluation of tralonide ointment, a new topical steroid. | 2016 | 5000463 | |
| a 13c-nmr spectroscopic study of alpha- and beta-streptomycin. | 2016 | 4826086 | |
| nobel error. | 2016 | 5029230 | |
| treatment of acquired choanal atresia. | 2016 | 5094544 | |
| pull-through ureteral reimplantation for reflux. | 2016 | 4930798 | |
| [selection of the optimal regime of controlled breathing for patients who have undergone surgery in the trendelenburg position]. | 2016 | 4888597 | |
| [neonatal tetany]. | 2016 | 4857413 | |
| circadian variation in reticulocyte counts and immuno-detectable erythropoietin titers. | 2016 | 4827740 | |
| change in stroke volume as related to change in total blood volume early after pulmonary surgery. | 2016 | 4913655 | |
| [experiences with an alkylating agent in rheumatoid arthtitis]. | 2016 | 5051964 | |
| [aortic coarctation syndrome in the newborn]. | 2016 | 5035074 | |
| [present forensic dentistry, from early times to today]. | 2016 | 4898140 | |
| [methylenecycline (rondomycin)]. | 2016 | 4965480 | |
| [70 years of associate professor mudr. olga valentová]. | 2016 | 4902979 | |
| [organization of polysubstrate processes on the surface of the small intestine. physiological and clinical importance]. | 2016 | 4821805 | |
| chlorpromazine and the untreated chronic schizophrenic: a long-term trial. | 2016 | 4862704 | |
| rare diseases, old drug, new knowledge. | 2016 | 4710441 | |
| [on the problem of the classification and malignancy of tumors of the sweat glands]. | 2015 | 4283929 | |
| [effect of methoxyflurane on the cardiovascular system]. | 2015 | 4409375 | |
| [the incidence of disablement from tuberculosis in 1973 (author's transl)]. | 2015 | 4453529 | |
| [case of ovarian thecoma]. | 2015 | 4350562 | |
| biostatics in dentistry. | 2015 | 4514262 | |
| [current problems in chronic coxopathy. ii. idiopathic decalcification of the hip]. | 2015 | 4391529 | |
| rupture of the aorta. a diagnostic triad. | 2015 | 4690502 | |
| a study of services and needs of teenage pregnant girls in the large cities of the united states. | 2015 | 4682630 | |
| [acute ulcers of the gastrointestinal tract]. | 2015 | 4666702 |