Publications

bactrian camel (camelus bactrianus) integrins alphavbeta3 and alphavbeta6 as fmdv receptors: molecular cloning, sequence analysis and comparison with other species.	integrins are heterodimeric adhesion receptors that participate in a variety of cell-cell and cell-extracellular matrix protein interactions. many integrins recognize rgd sequences displayed on extracellular matrix proteins and the exposed loops of viral capsid proteins. four members of the alphav integrin family of cellular receptors, alphavbeta3, alphavbeta6, alphavbeta1 and alphavbeta8, have been identified as receptors for foot-and-mouth disease virus (fmdv) in vitro, and integrins are belie ...	2009	19443046
sheep (ovis aries) integrins alphavbeta1 and alphavbeta6 related to foot-and-mouth disease virus infection: molecular cloning, sequence analysis and comparison with homologues.	four members of the alphav integrin family of cellular receptors, alphavbeta1, alphavbeta3, alphavbeta6, and alphavbeta8, have been identified as receptors for foot-and-mouth disease virus (fmdv) in vitro, and integrins are believed to be the receptors used to target epithelial cells in the infected animals. to analyse roles of the alphav integrins from a susceptible species as viral receptors, we have cloned sheep alphav, beta1, and beta6 integrin cdnas and compared them to those of other speci ...	2009	19555755
differences in the susceptibility of dromedary and bactrian camels to foot-and-mouth disease virus.	in this study, two sheep, eight dromedary camels and two bactrian camels were inoculated with foot-and-mouth disease virus (fmdv) type a sau 22/92. five naive dromedary camels and four sheep were kept in direct or indirect contact with the inoculated camels. the inoculated sheep, which served as positive controls, displayed typical moderate clinical signs of fmd and developed viraemia and high antibody titres. the presence of the virus was also detected in probang and mouth-swab samples for seve ...	2009	18687160