Publications

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genetic and pathobiologic characterization of pandemic h1n1 2009 influenza viruses from a naturally infected swine herd.since its initial identification in mexico and the united states, concerns have been raised that the novel h1n1 influenza virus might cause a pandemic of severity comparable to that of the 1918 pandemic. in late april 2009, viruses phylogenetically related to pandemic h1n1 influenza virus were isolated from an outbreak on a canadian pig farm. this outbreak also had epidemiological links to a suspected human case. experimental infections carried out in pigs using one of the swine isolates from th ...201020015998
association between the 2008-09 seasonal influenza vaccine and pandemic h1n1 illness during spring-summer 2009: four observational studies from canada.in late spring 2009, concern was raised in canada that prior vaccination with the 2008-09 trivalent inactivated influenza vaccine (tiv) was associated with increased risk of pandemic influenza a (h1n1) (ph1n1) illness. several epidemiologic investigations were conducted through the summer to assess this putative association.201020386731
design and validation of real-time reverse transcription-pcr assays for detection of pandemic (h1n1) 2009 virus.tracking novel influenza viruses which have the potential to cause pandemics, such as the pandemic (h1n1) 2009 virus, is a public health priority. pandemic (h1n1) 2009 virus was first identified in mexico in april 2009 and spread worldwide over a short period of time. well-validated diagnostic tools that are rapid, sensitive, and specific for the detection and tracking of this virus are needed. three real-time reverse transcription pcr (rt-pcr) assays for the amplification and detection of pande ...200919726603
adamantane resistance in circulating human influenza a viruses from alberta, canada (1970-2007).mutation in one of five key amino acid residues (positions 26, 27, 30, 31 and 34) within the m2 protein of influenza a viruses, leads to resistance against the adamantane class of anti-influenza drugs. to investigate the emergence and prevalence of adamantane resistance in alberta, canada (between 1970 and 2007), 381 influenza a positive samples (original patient specimens) or isolates (virus cultured from patient specimens) were analyzed for changes in these critical amino acid residues. our re ...200818258311
active surveillance for influenza infection in children; stollery children's hospital, 2003-2004 season. 200415481670
public opinion and the swine flu immunization program. 1978647572
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