Publications

mold and alternaria skin test reactivity and asthma in children in connecticut.	sensitivity to mold has been associated with asthma incidence, persistence, and severity.	2011	21457878
prevalence of and risk factors for canine tick infestation in the united states, 2002-2004.	knowledge of the geographic range and seasonal activity of vector ticks is important for determining which people or animals are at risk of acquiring tick-borne infections. several time-consuming methods requiring large-scale organization are used to map geographic and seasonal variations in tick distribution. a cost-effective, complementary approach to study tick distribution using a large nation-wide veterinary database is described in this paper. prevalence of canine tick infestation in 40 st ...	2007	17417959
a survey of environmental contamination with ascarid ova, wallingford, connecticut.	few studies have been conducted in the united states to quantify the potential risk associated with encountering zoonotic ascarid ova in the environment. in an effort to raise awareness and to better understand the risk of acquiring visceral larva migrans in south central connecticut, this environmental survey was conducted to determine the prevalence of ascarid ova (toxocara canis, toxocara cati, baylisascaris columnaris, and baylisascaris procyonis) in public areas of wallingford, connecticut, ...	2005	15815147
west nile virus activity--united states, august 18-24, 2004.	during august 18-24, a total of 154 cases of human west nile virus (wnv) illness were reported from 18 states (alabama, arizona, california, colorado, connecticut, florida, georgia, illinois, kentucky, minnesota, mississippi, missouri, nevada, new mexico, north carolina, south dakota, tennessee, and wisconsin).	2004	15329654
pre-west nile virus outbreak: perceptions and practices to prevent mosquito bites and viral encephalitis in the united states.	mosquitoes can transmit over 100 of the viruses that can cause encephalitis, meningitis, and hemorrhagic disease in humans (chin 2000; gubler 1996; monath 1989). while much is known about the ecology, epidemiology, and clinical manifestations of the arboviral encephalitides (campbell et al. 2002; centers for disease control and prevention 1997; gubler 1998; hayes 1989; hubálek and halouzka 1999), little empirical research exists regarding the u.s. population's knowledge of mosquitoes and arbovir ...	2003	14733669
a serosurvey of leptospirosis in connecticut peridomestic wildlife.	recently, leptospirosis has gained attention as a re-emerging infection in domestic dogs in the northeastern united states. in order to gain insight into the epizootiology of leptospirosis in this region, 109 small wild mammals (31 raccoons (procyon lotor), 30 skunks (mephitis mephitis), 28 opossums (didelphis virginiana), and 20 gray squirrels (sciurus carolinensis)) collected between february 27 and september 17, 2001 were tested for serologic evidence of exposure to five common leptospira ser ...	2003	14733671
dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the northeastern united states: impact of socioeconomic factors and population density.	home exposures to aeroallergens are an important environmental factor in allergic sensitization and in the development and exacerbation of asthma. we assessed variations in home concentrations of dust mite, cockroach, cat, and dog allergens in dust collected in the main living areas of asthmatics' homes by family income, mother's education, dwelling type, population density, household population density, and ethnicity in connecticut and south-central massachusetts. dust samples were collected at ...	2002	11940461
use of a c6 elisa test to evaluate the efficacy of a whole-cell bacterin for the prevention of naturally transmitted canine borrelia burgdorferi infection.	a commercially available c6 elisa kit was used to detect antibodies induced by natural infection with borrelia burgdorferi in dogs that lived in an area endemic for lyme disease. rates of infection were determined both for nonvaccinated dogs and those that had been vaccinated with a whole-cell b. burgdorferi bacterin (lyme vax, fort dodge animal health) before 6 months of age and were boostered annually. vaccinated dogs had an infection rate of 5% (8 of 163), whereas 64% (25 of 39) of the non-va ...	2002	12584679
risk factors for human exposure to raccoon rabies during an epizootic in connecticut.	the emergence of rabies among terrestrial wildlife poses increasing but poorly defined risks to people. in particular, events leading to human exposure to rabies virus via mammalian reservoirs remain elusive. thus, we determined those risk factors associated with human exposure to rabies-positive animals during a raccoon rabies epizootic in connecticut. existing passive surveillance data on animal rabies tests in connecticut from 1991 through 1994 were evaluated for demographic, ecological, and ...	2001	12653149
reactivity of serum samples of dogs and horses tested by use of class-specific recombinant-based enzyme-linked immunosorbent assays for detection of granulocytic ehrlichiosis.	to test serum samples of dogs and horses by use of class-specific recombinant-based elisa for establishing a diagnosis of granulocytic ehrlichiosis attributable to infection with organisms from the ehrlichia phagocytophila genogroup.	2001	11560261
reactivity of dog sera to whole-cell or recombinant antigens of borrelia burgdorferi by elisa and immunoblot analysis.	enzyme-linked immunosorbent assays (elisas) with separate preparations of 10 purified recombinant antigens of borrelia burgdorferi sensu stricto were used to test sera from 36 dogs not vaccinated with whole cells of this agent and from five dogs vaccinated with whole-cell b. burgdorferi bacteria. all dogs lived in tick-infested areas of connecticut and south-eastern new york state, usa. the non-vaccinated dogs had limb or joint disorder, lameness and fever during the period 1984-1991 and had ant ...	2001	11599738
public awareness of rabies and compliance with pet vaccination laws in connecticut, 1993.	to determine the degree of public awareness of rabies and compliance with cat and dog vaccination laws in connecticut in 1993.	1998	9604022
rabies surveillance in the united states during 1997.	in 1997, 49 states, the district of columbia, and puerto rico reported 8,509 cases of rabies in nonhuman animals and 4 cases in human beings to the centers for disease control and prevention. nearly 93% (7,899) were wild animals, whereas 7% (610) were domestic species. the total number of reported cases increased 19.4% from that of 1996 (7,128 cases). increases were apparent in each of the major species groups, with the exception of cattle. the relative contributions of these groups to the total ...	1998	9861958
antibodies to ehrlichia equi in dogs from the northeastern united states.	to determine whether dogs living in tickinfested areas of the northeastern united states had been exposed to ehrlichia equi, an etiologic agent of granulocytic ehrlichiosis.	1997	9364226
pesticide use by licensed applicators for the control of ixodes scapularis (acari: ixodidae) in connecticut.	to assess the use of insecticides for tick control by commercial applicators in connecticut, a questionnaire was mailed to 897 individuals and businesses with ornamental and turf pesticide applicator licenses. in total, 348 completed surveys were returned (38.8%). the majority of the respondents considered themselves lawn care (41.1%), landscape (31.3%) or tree care (12.6%) providers. tick control services were offered by 16.4% (n = 57) of the respondents, all of whom apply insecticides for tick ...	1997	9379461
hemocytic rickettsia-like organisms in ticks: serologic reactivity with antisera to ehrlichiae and detection of dna of agent of human granulocytic ehrlichiosis by pcr.	ixodid ticks were collected from connecticut, massachusetts, missouri, pennsylvania, rhode island, and british columbia (canada) during 1991 to 1994 to determine the prevalence of infection with hemocytic (blood cell), rickettsia-like organisms. hemolymph obtained from these ticks was analyzed by direct and indirect fluorescent antibody (fa) staining methods with dog, horse, or human sera containing antibodies to ehrlichia canis, ehrlichia equi, or rickettsia rickettsii. of the 693 nymphal and a ...	1995	8567911
not just child's play. hmo and department of education help teachers educate kids about wellness. m.d. health plan, north haven, ct.		1994	10138666
security dogs cut crime.		1992	10124925
rabies surveillance in the united states during 1991.	in 1991, 49 states, the district of columbia, and puerto rico reported 6,972 cases of rabies in nonhuman animals and 3 cases in human beings to the centers for disease control. ninety-one percent (6,354 cases) were wild animals, whereas 8.9% (618 cases) were domestic species. the total number of reported cases of rabies increased 42.9% over that of 1990 (4,881 cases), with most of the increase resulting from continued spread of the epizootic of rabies in raccoons in the mid-atlantic and northeas ...	1992	1483899
relationship between development of antibodies to borrelia burgdorferi in dogs and the subsequent development of limb/joint borreliosis.	the relationship between antibody production and the subsequent development of limb/joint disorders of borreliosis was examined in dogs from south central connecticut. dogs without signs of illness, determined by physical examination, were selected from dogs being tested for dirofilaria immitis. an elisa was used to detect antibodies to borrelia burgdorferi in 234 apparently healthy dogs during 1988. these dogs were monitored for 20 months after initial analyses to determine the prevalence of li ...	1992	1548169
rabies surveillance in the united states during 1989.	in 1989, 4,808 cases of rabies in animals other than human beings were reported to the centers for disease control, 1.8% more (4,724 to 4,808) than in 1988. eighty-eight percent (4,224/4,808) of those affected were wild animals and 12% (584/4,808) were domestic animals. cases were reported from 49 states, the district of columbia, and puerto rico; hawaii remained rabies-free. skunks (1,657) continued to be the most commonly reported rabid wild animal. for the second consecutive year, more cats ( ...	1990	2276949
canine ehrlichiosis in connecticut.	the first case of canine ehrlichiosis in connecticut is reported. a female brittany spaniel from milford presented with lethargy, anorexia, fever, petechiae, splenomegaly, thrombocytopenia, anemia, elevated serum alkaline phosphatase, lymphopenia, and hypoalbuminemia. serologic analysis revealed antibodies to ehrlichia canis (titer, 1:2,560). this documents a more northern geographic distribution in the united states for this infectious agent than had previously been suspected.	1990	2312682
persistence of antibodies to borrelia burgdorferi in dogs of new york and connecticut.	multiple blood samples were obtained from privately owned dogs living in tick-infested areas of new york (westchester county) and connecticut, where lyme disease in human beings has been reported. of the 175 dogs examined, 127 (72.6%) had limb/joint disorder, whereas the remaining 48 dogs were considered healthy. results of analysis of 419 serum samples revealed igm antibody to borrelia burgdorferi in healthy and lame dogs during all seasons. prevalence of seropositivity was significantly (p les ...	1990	2329074
rabies surveillance, united states, 1988.	the primary purpose of the annual report on rabies surveillance is to assist local and state public health officials in the planning of rabies control programs and to guide health professionals in evaluating the need for rabies postexposure prophylaxis in patients who are exposed to animals that may be rabid. in 1988, a total of 4,724 cases of animal rabies were reported by 47 states, the district of columbia, and puerto rico, similar to the total (4,729) for 1987. no human cases of rabies were ...	1989	2505046
ticks and biting insects infected with the etiologic agent of lyme disease, borrelia burgdorferi.	members of 18 species of ticks, mosquitoes, horse flies, and deer flies were collected in southeastern connecticut and tested by indirect fluorescent-antibody staining methods for borrelia burgdorferi, the etiologic agent of lyme disease. an infection rate of 36.2% (116 tested), recorded for immature ixodes dammini, exceeded positivity values for all other arthropod species. prevalence of infection for hematophagous insects ranged from 2.9% of 105 hybomitra lasiophthalma to 14.3% of seven hybomi ...	1988	3170711
immunoblot analysis of immunoglobulin g response to the lyme disease agent (borrelia burgdorferi) in experimentally and naturally exposed dogs.	immunoblots were used to study the immunoglobulin g response to borrelia burgdorferi in experimentally and naturally exposed dogs. adsorption studies confirmed that the antibodies were specific for b. burgdorferi. experimentally exposed dogs were asymptomatic. naturally exposed dogs included both asymptomatic animals and animals showing signs compatible with lyme disease. naturally exposed dogs were from four geographic regions of the country. no differences were detected between immunoblot patt ...	1988	3366860
clinical and serologic studies of canine borreliosis.	during 1984 and 1985, blood samples were obtained from 271 dogs that were suspected of having borreliosis. the dogs lived in areas known to be infested with ticks and had been examined because of limb/joint disorders or for unknown illnesses marked by fever, anorexia, or fatigue. lameness had been the most frequently reported clinical manifestation. analyses of serum specimens, by an indirect fluorescent antibody (ifa) method or by an elisa, detected antibodies to borrelia burgdorferi, the etiol ...	1987	3319989
spirochetes in ticks and antibodies to borrelia burgdorferi in white-tailed deer from connecticut, new york state, and north carolina.	ticks were screened for spirochetes and serum samples from white-tailed deer (odocoileus virginianus) were assayed for antibodies to borrelia burgdorferi during 1983-1984. using fluorescein isothiocyanate-labeled rabbit antibodies produced to b. burgdorferi, the etiologic agent of lyme disease, spirochetes were detected in ixodes dammini (10.5% of 1,193) and dermacentor albipictus (0.6% of 157) adults from connecticut, i. dammini nymphs (49.1% of 108) and adults (64.7% of 99) from armonk, new yo ...	1986	3520030
borreliosis in dogs from southern connecticut.	blood samples were obtained from dogs in tick-infested regions of southern connecticut to assess canine exposure to borrelia burgdorferi, the etiologic agent of lyme disease in human beings. an indirect fluorescent antibody test detected immunoglobulin (ig)m antibodies at titers of 1:64 to 1:512 in 22 of 84 serum samples previously shown to be positive with a polyvalent rabbit anti-dog total ig conjugate. analyses of paired serum samples from 20 seropositive dogs revealed temporal differences in ...	1985	3997647
arthritis caused by borrelia burgdorferi in dogs.	from october 1982 to may 1984, we studied 34 dogs from the lyme, conn area that had a history of tick exposure and lameness associated with pain, warmth, and/or swelling in one or more joints. large numbers of polymorphonuclear leukocytes were seen in giemsa-stained smears of synovial fluid from 9 dogs, and spirochetes (borrelia burgdorferi) were found in 1 sample by darkfield microscopy and immunoperoxidase techniques. the geometric mean antibody titer to b burgdorferi in the 34 dogs was 1:2,70 ...	1985	3997648
antibodies to spotted fever-group rickettsiae in dogs and prevalence of infected ticks in southern connecticut.	blood samples and ticks were obtained from dogs to assess canine exposure to spotted fever-group (sfg) rickettsiae during 1978-1980 in southern connecticut. of the 1,576 dog sera screened by microimmunofluorescence. 174 (11.0%) contained specific antibodies at titers greater than or equal to 1:64 against rickettsia montana (n = 34), r rickettsii (n = 31), r rhipicephali (n = 19), or the unclassified 369-c rickettsia (n = 90). end points greater than or equal to 1:8,192 to r rickettsii and to r r ...	1982	6803626
spirocerca lupi (rudolphi, 1809) nodule in the rectum of a dog from connecticut.	a small nodule causing repeated rectal prolapse was surgically removed from a four year old dachshund residing for her entire life in connecticut. histologic examination of the biopsy specimen revealed sections of spirocerca lupi (rudolphi 1809) surrounded by a granulomatous reaction and fibrous wall.	1980	7379553
vertebrate host relationships and distribution of ixodid ticks (acari: ixodidae) in connecticut, usa.		1980	7420362
rocky mountain spotted fever in connecticut: human cases, spotted-fever group rickettsiae in ticks, and antibodies in mammals.	three parameters were used in 1976 and 1977 to assess the status of rocky mountain spotted fever (rmsf) in connecticut--compilation and review of clinical data on suspected human cases for the 13-year period 1965--1977, examination of tick tissues for spotted fever-group rickettsiae by the hemolymph test and direct immunofluorescence, and analyses of mammalian sera for antibodies against rickettsia rickettsii. there were six presumptive rmsf cases which probably originated in connecticut. four o ...	1979	111543
the research animal and the significance of a health monitoring program.	the criteria for the selection of stocks and strains of laboratory animals were discussed. these include metabolic and environmental factors as well as the presence or introduction of infectious agents. the investigator is now concerned with his experimental animals from conception to death, not just during an experiment. the basis of a health monitoring program to ascertain the health status of incoming animals, to evaluate the status of the environment, and to document the ongoing status of a ...	1976	818449
canine alimentary neoplasia.		1973	4196657
canine filariasis (dirofilaria immitis and dipetalonema reconditum): survey in southwestern connecticut.		1973	4795934
age, breed, and sex distribution in connecticut dogs.		1967	6069989
dirofilariasis in connecticut dogs.		1966	4164190
a program of education and public relations contributing to passage of the connecticut "dogs for research" bill in 1963.		1963	14083205