Publications

influence of il-6, il-8, and tgf-β1 gene polymorphisms on the risk of human papillomavirus-infection in women from pernambuco, brazil.	human papillomavirus (hpv) infections are strongly associated with the development of cervical intraepithelial neoplasias and invasive cervical cancer. polymorphisms in cytokine-encoding genes and behavioural cofactors could play an important role in protecting an individual against viral infections and cancer. here, we investigated whether il-6 -174 g>c, il-8 +396 g>t, and tgf-β1 +869 g>c and +915 g>c polymorphisms were associated with susceptibility to hpv infection in women from north-east (p ...	2016	27783717
ccr2 and ccr5 genes polymorphisms in women with cervical lesions from pernambuco, northeast region of brazil: a case-control study.	polymorphisms in chemokine receptors play an important role in the progression of cervical intraepithelial neoplasia (cin) to cervical cancer (cc). our study examined the association of ccr2-64i (rs1799864) andccr5-δ32 (rs333) polymorphisms with susceptibility to develop cervical lesion (cin and cc) in a brazilian population. the genotyping of 139 women with cervical lesions and 151 women without cervical lesions for the ccr2-64i and ccr5-δ32 polymorphisms were performed using polymerase chain r ...	2016	26982176
association between p21 ser31arg polymorphism and the development of cervical lesion in women infected with high risk hpv.	infection by high-risk human papillomavirus (hr-hpv) and single nucleotide polymorphism (snp) in genes involved in cell cycle control, as p21 and p27, are important factors in the development of different types of human cancers. this study aims at investigating whether both the p21 ser31arg and p27 v109g polymorphisms are associated with susceptibility to the development of cervical lesions in women hr-hpv positive. we analyzed 132 women hpv positive and with cervical lesions or cc and 154 healt ...	2016	26886286
chlamydia trachomatis infection and human papillomavirus in women with cervical neoplasia in pernambuco-brazil.	chlamydia trachomatis (ct) is the most common bacterial cause of sexually transmitted disease. high-risk human papillomavirus (hr-hpv) is considered the main etiological agent for cervical neoplasia. evidences showed that the presence of co-infection of ct and hr-hpv plays a central role in the etiology of cervical intraepithelial neoplasia (cin) and cervical cancer. the goals of this study were: evaluate the human papillomavirus (hpv) and ct prevalence among brazilian women with abnormal cytolo ...	2014	24395291
[prevalence of human papillomavirus genotypes: comparison between three detection methods in patients of pernambuco, brazil].	to compare three methods for the detection of hpv infection and to determine the prevalence of the genotypes found.	2011	22231166
frequency and types of human papillomavirus among pregnant and non-pregnant women with human immunodeficiency virus infection in recife determined by genotyping.	women with human immunodeficiency virus (hiv) infection present a higher risk of infection by the human papillomavirus (hpv) and cervical cancer. to determine hpv genotypes and frequencies among hiv-positive women, an analytical cross-sectional study was carried out on 147 women (51 were pregnant and hiv-positive, 45 pregnant and hiv-negative and 51 hiv-positive and not pregnant), who were attended at a maternity hospital in recife between april 2006-may 2007. they answered a questionnaire and u ...	2009	19820838
hpv31 and hpv33 incidence in cervical samples from women in recife, brazil.	human papillomavirus (hpv) has been extensively studied concerning genomic structure, infection mechanisms, and diversity of types, as well as disease progression stages and development of vaccines. hpv type prevalence can differ in specific populations in different countries, according to ethnicity. this is the first report of an integrated project to evaluate the incidence of hpv types in different regions in brazil in order to obtain data for vaccine development. cervical samples were collect ...	2009	20013657
[epidemiological aspects of cervical neoplasms].	a review concerning the epidemiological issues relating to cervical cancer, one of the most frequent in the women of developing countries, was undertaken in brazil, the incidence rate varies from 23.7/100,000 in porto alegre to 83.2/100,000 in recife. in the united states, the 1978 incidence rate was 6.8/100,000 in white women and 14.7/100,000 among black women. several studies have suggested the hypotheses that cervical cancer could be related to some venereal agent. the evidences have shown th ...	1991	1668183
epidemiologic correlates of cervical neoplasia and risk of human papillomavirus infection in asymptomatic women in brazil.	to investigate whether the epidemiologic correlates of cervical cancer are predictors of infection with genital human papillomavirus (hpv), we performed a prevalence survey in two metropolitan areas of brazil, recife and são paulo. the data records of four randomly selected hpv-negative women were matched on the basis of age, clinic, and admission period with those of each of 136 patients with positive hpv dna hybridizations. anal intercourse [prevalence rate ratio (prr) = 1.7] and current pregn ...	1989	2536815