Publications

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clinical manifestations and microbiology of acute otitis media with spontaneous otorrhea in children.in taiwan, clinical and microbiological data on acute otitis media (aom) with spontaneous otorrhea in children are limited.201323757372
antimicrobial resistance of moraxella catarrhalis isolates in taiwan.background/purpose: the prevalence of ampicillin-resistant moraxella catarrhalis has been higher in taiwan than in other countries, with reports of 97.7% in the 1990s. the aims of this study were to assess resistance trends for m. catarrhalis, which causes respiratory tract infections, against several classes of oral antibiotics and to compare the minimum inhibitory concentration (mic) of antimicrobial agents against m. catarrhalis isolates between 1993-1994 and 2001-2004. methods: clinical isol ...201122154675
Nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Alloiococcus otitidis in young children in the era of pneumococcal immunization, Taiwan.We applied a multiplex polymerase chain reaction (PCR) and culture to detect Streptococcus pneumoniae and detected 3 other respiratory pathogens--Haemophilus influenzae, Moraxella catarrhalis, and Alloiococcus otitidis--simultaneously by PCR, in the nasopharynx of 386 children aged under 5 y. S. pneumoniae was the most common pathogen carried by children in all age groups, with the rate ranging from 15.8% in children aged 3-4 y to 28.6% in children aged 2-3 y. H. influenzae and M. catarrhalis sh ...201121892897
clinical spectrum of acute rhinosinusitis among atopic and nonatopic children in taiwan.rhinitis and sinusitis are very common medical conditions and have been shown to be frequently associated. the role of allergies in the pathogenesis of chronic rhinosinusitis has been confirmed; however, the role of allergies in acute rhinosinusitis is debatable. nonetheless, allergies are an important factor in the development of rhinosinusitis.201122051141
comparison of in vitro activities of tigecycline with other antimicrobial agents against streptococcus pneumoniae, haemophilus influenzae, and moraxella catarrhalis in taiwan.we compared the in vitro activities of tigecycline to those of other agents against 300 nonduplicate isolates of streptococcus pneumoniae (194 isolates), haemophilus influenzae (60 isolates), and moraxella catarrhalis (46 isolates) recovered from patients treated in three major hospitals in taiwan from august through december, 2003. all of these isolates were inhibited at 0.5 mg/l of tigecycline. for s. pneumoniae isolates, 72% were not susceptible to penicillin (69% intermediate and 3% resistan ...200616922631
positive blood cultures in pediatric emergency department patients: epidemiological and clinical characteristics.to determine the frequency of the emergency department (ed) visits of bacteraemic children and to compare the clinical characteristics of the discharged patients with those of the admitted patients.200516302571
high prevalence of antibiotic resistance in isolates from the middle meatus of children and adults with acute rhinosinusitis.the pathogens in acute rhinosinusitis are similar worldwide. an increase in antibiotic resistance has been shown in a large number of studies in recent years. the prevalence of resistance varies greatly in different countries. this study was performed to determine the endemic prevalence of antibiotic resistance in pathogens of acute rhinosinusitis in taiwan.200415706987
multicenter surveillance of antimicrobial resistance of streptococcus pneumoniae, haemophilus influenzae, and moraxella catarrhalis in taiwan during the 1998-1999 respiratory season.a susceptibility surveillance study of 276 isolates of streptococcus pneumoniae, 301 of haemophilus influenzae, and 110 of moraxella catarrhalis was carried out from november 1998 to may 1999 in taiwan. high rates of nonsusceptibility to penicillin (76%), extended-spectrum cephalosporins (56%), azithromycin (94%), clarithromycin (95%), and trimethoprim-sulfamethoxazole (tmp-smx) (65%) for s. pneumoniae isolates and high rates of nonsusceptibility to amoxicillin (58%) and tmp-smx (52%) for h. inf ...200010770773
antimicrobial susceptibility and beta-lactamase production of moraxella catarrhalis isolates in taiwan.between 1 august 1993 and 31 july 1994, 135 clinical isolates of moraxella catarrhalis were collected from 12 large medical laboratories in taiwan. the majority of specimens came from sputum (124 isolates). other specimens included four isolates from throats, three isolates from wounds or pus, two isolates from eyes, one isolate from blood and one from cerebrospinal fluid. epidemiologically, m. catarrhalis isolates were found frequently in winter and spring with a peak in february, and only spor ...19958696169
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