Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| associations between hla class i alleles and escape mutations in the hepatitis b virus core gene in new zealand-resident tongans. | the full repertoire of hepatitis b virus (hbv) peptides that bind to the common hla class i molecules found in areas with a high prevalence of chronic hbv infection has not been determined. this information may be useful for designing immunotherapies for chronic hepatitis b. we identified amino acid residues under positive selection pressure in the hbv core gene by phylogenetic analysis of cloned dna sequences obtained from hbv dna extracted from the sera of tongan subjects with inactive, hbeag- ... | 2010 | 19846510 |
| polymorphism in intron 1 of the interferon-gamma gene influences both serum immunoglobulin e levels and the risk for chronic hepatitis b virus infection in polynesians. | intron 1 of the interferon-gamma (ifng) gene contains two polymorphisms. the 12 ca-repeat allele of the +875 ifngca microsatellite and the t allele of the +a874t single nucleotide polymorphism (snp) have been associated with increased in vitro ifng production and a variety of clinical phenotypes. the purpose of this study was to determine whether these polymorphisms influence total serum ige levels [tsige] and the outcome of a hepatitis b virus (hbv) infection. ifngca and +a874t were typed in 18 ... | 2007 | 17211638 |
| near elimination of hepatitis b virus infections among hawaii elementary school children after universal infant hepatitis b vaccination. | hawaii implemented routine infant hepatitis b vaccination in 1992 and required it for school entry in 1997. previously, in 1989, a serologic survey among hawaii school children in grades 1 to 3 indicated that 1.6% had chronic hepatitis b virus infection, and 2.1% had resolved infection. we conducted a follow-up survey to examine changes in hepatitis b virus infection rates. | 2006 | 17015529 |
| genotype and phylogenetic characterization of hepatitis b virus among multi-ethnic cohort in hawaii. | hepatitis b virus (hbv) genomes in carriers from hawaii have not been evaluated previously. the aim of the present study was to evaluate the distribution of hbv genotypes and their clinical relevance in hawaii. | 2004 | 15259069 |
| long term antibody response to hepatitis b vaccination beginning at birth and to subsequent booster vaccination. | few studies have examined the long term persistence of antibody after hepatitis b immunization beginning at birth and the response to a subsequent challenge with a booster dose of vaccine. | 2003 | 12586980 |
| the t(1858) variant predisposing to the precore stop mutation correlates with one of two major genotype f hepatitis b virus clades. | the precore mutation g(1896)-->a occurs frequently in anti-hbe-positive carriers of hbsag with t(1858) in the stem of the encapsidation signal. hepatitis b virus (hbv) genotype f, considered an amerindian genotype, subdivides into two clades and the precore mutation occurs in central american f strains. to investigate the relationship between substitutions at position 1858 and these clades, the precore and small s genes of 48 strains of hbv genotype f were subjected to phylogenetic analyses. iso ... | 2003 | 12867638 |
| hepatitis b and c virus serologies among japanese americans with hepatocellular carcinoma. | a cohort of 5924 japanese american men was examined between 1967 and 1970 for hepatocellular carcinoma (hcc). by 1992, 24 incident cases of hcc were histologically confirmed in the group. frozen serum samples from the 24 men with hcc and 72 age-matched controls were tested for hepatitis b surface antigen (hbsag), antibodies to hepatitis b core antigen, antibodies to hbsag, and antibodies to hepatitis c virus. hbsag was detected in 15 (62.5%) of 24 hcc cases compared with 2 (2.8%) of 72 controls ... | 1996 | 8648223 |
| the influence of a maternal chronic hepatitis b virus infection on the repertoire of transcribed t-cell receptor beta chain variable region genes in human cord blood. | we used an anchor polymerase chain reaction method to compare the repertoires of transcribed t-cell receptor beta chain variable region (v beta) genes in cord blood t cells from neonates of hepatitis b surface antigen (hbsag) positive (n = 40) and hbsag negative (n = 40) women. fifteen of the hbsag positive women were hepatitis b e antigen (hbeag) positive, and 25 were hbeag negative. the percentage of v beta 7.4 transcripts was lower in cord blood t cells from neonates of hbsag-positive relativ ... | 1995 | 7557848 |
| the blackfly simulium buissoni and infection by hepatitis b virus on a holoendemic island of the marquesas archipelago in french polynesia. | the hematophagous blackfly simulium buissoni causes skin lesions on an island in the marquesas archipelago that is holoendemic for hepatitis b virus (hbv). to test the hypothesis of the possible role of this fly in the transmission of hepatitis b, 506 children (age range 2-11 years) were examined for the presence of skin lesions, and attempts were made to detect hbv dna in and on blackflies using two polymerase chain reaction methods. the mean number of skin lesions showed a positive correlation ... | 1993 | 8333570 |
| hepatitis b virus infection in honolulu students. | to determine hepatitis b virus (hbv) carrier and infection rates and hbv epidemiology in honolulu students. | 1993 | 8414830 |
| effect of a hepatitis b vaccination program on the prevalence of hepatitis b virus infection. | in april 1991, surveys for serologic evidence of hepatitis b virus (hbv) infection were conducted among 3- to 4-year-old children born after a hepatitis b immunization program of newborns began and among 6- to 11-year-old children targeted for early childhood vaccination in american samoa. compared with 3- to 4-year-olds tested in 1991, children tested at baseline in 1985 were more likely to have been infected with hbv (5/40 vs. 2/93; prevalence ratio [pr] = 5.8, 95% confidence limits [cl] = 1.2 ... | 1993 | 8418167 |
| mutations of p53 gene in hepatocellular carcinoma: roles of hepatitis b virus and aflatoxin contamination in the diet. | mutations of the p53 tumor suppressor gene have been reported in 50% of patients with hepatocellular carcinoma (hcc) from china and south africa. these reports suggested an association of p53 mutations with high levels of aflatoxin in the diet. most studies of p53 and hcc, however, have not fully evaluated the possible role of the hepatitis b virus (hbv). aflatoxin is a substance produced by food mold that is known to cause hcc in experimental animals. | 1992 | 1279184 |
| [respective importance of vertical and horizontal transmission of hepatitis b in the australian archipelago (french polynesia). preliminary results of the vaccination of newborns]. | a seroepidemiological survey of hepatitis b was conducted in 1988 in the austral archipelago (french polynesia) in a randomly selected sample of 957 persons, has showed an infection rate (at least one positive marker) with hbv of 64.1% for the entire archipelago. among women of child-bearing age, hbs ag carriage rate was 11.45% of whom 19.1% were so hbe ag carriers. among infants hbs ag carriage rate was 2.1% and among juveniles it was 10.6%. in this area horizontal transmission of hbv is essent ... | 1991 | 1840244 |
| [epidemiology of primary liver cancer in french polynesia]. | thirty-one cases of primary liver cancer recorded since 1980 to 1988 in french polynesia are studied. four risk factors are brought to the fore: male, more than 50 years old, birth in austral archipelago and in this case aghbs carriage. the relative risk for birth in austral archipelago reach to 9.23. the relative risk for aghbs carriers from this archipelago reach to 42.7. costs of primary liver cancer and to immunization against hepatitis b virus are compared. authors suggest to start an immun ... | 1990 | 1964882 |
| incidence of antibodies against human immunodeficiency virus, human t-cell lymphotropic virus type 1, hepatitis b virus, hemorrhagic fever with renal syndrome virus and chlamydia in tonga and western samoa. | among the populations of tonga and western samoa, serum antibodies against human immunodeficiency virus or hemorrhagic fever with renal syndrome virus were not detected (0/904 and 0/192). no serum samples were considered to be positive for antibody against human t-cell lymphotropic virus type 1 (0/527). hepatitis b antigen and antibody were found in 4% (8/192) and 47% (90/192), respectively. chlamydia trachomatis igg and c. psittaci igg antibodies were detected in 39% (75/192) and 47% (91/192), ... | 1990 | 2126048 |
| prevalence of hepatitis b virus infection in the austral archipelago, french polynesia: identification of transmission patterns for the formulation of immunization strategies. | a sero-epidemiological survey of hepatitis b virus (hbv) infection in a randomly selected sample of 957 persons from the population of the austral island group in french polynesia was conducted as a first step before developing an immunization programme strategy. prevalence rates of hbsag ranged from 3.09% to 27% in the different islands of the group with a weighted mean of 10.48%, while the prevalence rate for at least one marker ranged from 46.91% to 81.03% with a weighted mean of 64.12%. in t ... | 1990 | 2389322 |
| htlv-1, hiv-1, hepatitis b and hepatitis delta in the pacific and south-east asia: a serological survey. | blood samples from 13 locations in the pacific and south-east asia were tested for evidence of infection with human t-cell lymphotropic virus type-1 (htlv-1), human immunodeficiency virus (hiv-1), hepatitis b virus (hbv) and hepatitis delta virus (hdv). no samples were positive for antibody to hiv-1. antibodies to htlv-1 were found in samples from five locations, the maximum prevalence being 19%, in vanuatu. serological markers of hbv infection were found in all locations, the maximal prevalence ... | 1988 | 2892692 |
| hepatitis delta virus infection: a recently imported disease in new zealand. | in a study of 565 hepatitis b antigen (hbsag) positive persons from the auckland region, antibody to the hepatitis delta virus was detected in 38. the largest number were in samoans (61%) although the infection was present in some other pacific islanders. among hbsag positive healthy blood donors, antenatal patients and acute hepatitis patients between 3.8 and 4.8% were anti-delta positive; while 28% of chronic hepatitis patients were positive suggesting an association between this disease and d ... | 1987 | 3454892 |
| prevalence of hepatitis b virus infection in tonga: identifying high risk groups for immunization with hepatitis b vaccine. | a serological survey for evidence of hepatitis b virus (hbv) infection was conducted in the kingdom of tonga as the first step in developing a strategy for an immunization programme. there were 414 individuals from the general population plus 137 pregnant women included in the survey. hbsag was found in 20% of the general population and 88% had one or more serologic markers of hbv infection. in the 5-9 year age group, 80% of the children had one or more markers of hbv, and in the 10-19 year age ... | 1986 | 2950066 |
| risk factors associated with hepatitis b infection in antenatal patients. | risk factors associated with hbsag carriers were prospectively examined in 1821 women attending the antenatal clinic of an inner-city obstetrics hospital. of the sample, 3.2% were hbsag carriers and 28.7% of 725 tested for anti-hbs were positive. birth in a country where the prevalence of hbsag is high and aboriginal ancestry were the major associated factors rather than a past history of hepatitis or intravenous drug use. women from indochina or the pacific region, if hbsag-positive, were more ... | 1985 | 3867341 |
| the prevalence of antibodies to hepatitis a and b viruses in port chalmers residents. | 1982 | 6281700 | |
| hepatitis b virus infections in melanesians and polynesians in new caledonia. | hepatitis b virus infections were examined in two ethnically different pacific island groups, 532 melanesians and 401 polynesians, living under similar environmental circumstances on the island of ouvea, new caledonia. high hepatitis b virus infection rates (melanesians, 89.3%, and polynesians, 86.3%) and hepatitis b surface antigen (hbsag) carrier rates (melanesians, 11.7%, and polynesians, 8.0%) were observed in both groups. the carrier rate for hbsag was generally higher in men, particularly ... | 1981 | 7304571 |
| the prevalence of hepatitis b infection amongst urban and rural populations in western samoa. | a group of 240 urban and 200 rural dwellers in western samoa over the age of 20 years was studied for serological evidence of current or past infection with hepatitis b virus (hbv). overall, 5.5% of subjects were found to be currently infected with hbv and a further 74.5% showed detectable levels of antibody. antibody to the hepatitis b core antigen was found to be a better marker of past infection than antibody to the surface antigen of the virus. both the infection rate and carrier rate were h ... | 1981 | 7462598 |
| prevalence of antibody to hepatitis a and hepatitis b viruses in selected populations of the south pacific. | five island populations representing the three major cultural groups of the south pacific--polynesia, micronesia, melanesia--were studied for prevalence of antibody to hepatitis a virus (anti-hav) and of antibody to the core antigen of hepatitis b virus (anti-hbc). sera were collected in the late 1950s and early 1960s, selected where possible for appropriate age and sex distributions, and were tested by radioimmunoassay. rather marked differences in prevalence were observed. anti-hbc patterns co ... | 1979 | 224696 |
| a seroepidemiologic study of infection with hav and hbv in five pacific islands. | a batch of 1025 serum samples, obtained from healthy subjects and hospital patients from five pacific islands (viti levu, funafuti, niue, rarotonga and upolu) were tested for antibody to hepatitis a virus (anti-hav), hepatitis b surface antigen (hbsag) and antibody to hepatitis b surface antigen (anti-hbs) by solid phase radioimmunoassay (spria). high frequencies of anti-hav were observed in each population (funafuti, 79.9%; upolu, 81.6%; viti levu, 84.3%; rarotonga, 95.0%; and niue, 95.2%), and ... | 1979 | 224697 |
| [au antigens and antibodies in human sera from french polynesia]. | 1971 | 5004899 | |
| hepatitis-associated (australia) antigen in hawaii. | 1970 | 5490962 | |
| hepatitis associated antigen (haa) in hawaii. | 1970 | 5517044 |