Publications

deoxycholic acid formation in gnotobiotic mice associated with human intestinal bacteria.	in humans and animals, intestinal flora is indispensable for bile acid transformation. the goal of our study was to establish gnotobiotic mice with intestinal bacteria of human origin in order to examine the role of intestinal bacteria in the transformation of bile acids in vivo using the technique of gnotobiology. eight strains of bile acid-deconjugating bacteria were isolated from ex-germ-free mice inoculated with a human fecal dilution of 10(-6), and five strains of 7alpha-dehydroxylating bac ...	2006	17152920
innate mechanisms for bifidobacterium lactis to activate transient pro-inflammatory host responses in intestinal epithelial cells after the colonization of germ-free rats.	bifidobacteria comprise a dominant microbial population group in the human intestinal tract with purported beneficial health effects on the host. in this study, we characterized the molecular mechanisms for the initial interaction of probiotic bifidobacterium lactis strain bb12 with native and intestinal epithelial cell (iec) lines. we showed that b. lactis-monoassociated fisher f344 rats transiently induce phosphorylation/activation of the nf-kappab transcriptionally active subunit rela and the ...	2005	16011513
electron microscopic studies on the interaction between normal mice peritoneal phagocytes and treponema hyodysenteriae, treponema innocens and bacteroides vulgatus.	one hundred and twenty female mice (cf1 strain) were divided into three groups of 40. the first group was injected intraperitoneally with broth cultures of treponema hyodysenteriae. the second group was injected with a combination of t. hyodysenteriae and bacteroides vulgatus. the third group was injected with treponema innocens. peritoneal wash from four mice of each group was collected at eight time intervals postinjection, then prepared for and examined by light and electron microscopy. perit ...	1986	3742364
characterization of cephalosporinases from bacteroides fragilis, bacteroides thetaiotaomicron and bacteroides vulgatus.	the susceptibility of 80 bacteroides fragilis group strains isolated from clinical specimens to beta-lactam antibiotics was investigated by agar dilution method. twenty strains showed high resistance to the antibiotics. the resistance level of the isolates to cephaloridine was related to the amount of beta-lactamase activity (cephalosporinase; csase) produced. b. fragilis gn-11477, b. thetaiotaomicron gn11478 and b. vulgatus gn11479 were selected from among the csase producing strains, and the e ...	1983	6332105