Publications

[evolution of the repartition of enteropathogenic enterobacteria serotypes isolated in algeria from 1974 to 1977].	the authors survey the enteropathogenic enterobacteria studied from 1974 to 1977 and draw the following conclusions : s. typhi is still the predominant serotype. among salmonella, other than s. typhi and s. paratyphi, s. wien remains the most frequently reported serotype while progressively decreasing from 1974 to 1976 and is supplanted by s. infantis in 1977. among the 847 strains of shigella examined, a high frequency of shigella flexneri is noted with shigella sonnei following by a wide margi ...	1978	262974
brain growth-promoting activity in human serum: relationship to growth hormone and somatomedin.	brain growth-promoting activity and somatomedin activity were assessed in serum collected from patients with pituitary disorders of gh secretion. brain growth-promoting activity correlated with somatomedin activity in serum, and both rose in response to gh administration.	1978	263343
[reiter's disease in dysentery].		1978	347714
fluoride-induced mineralization within vacuoles in maturative ameloblasts of the rat.	dense crystalline deposits appeared within vacuoles in rat maturative ameloblasts as a result of repeated injections of sodium fluoride. the crystals assumed varied arrangements but were always observed within intracellular vacuoles. the crystals resemble those of normal enamel and resist microincineration. they are readily dissolved by decalcification and leave behind an organic framework which matches the outline of the crystals. an experimental model is presented which may be useful in furthe ...	1978	347979
plating procedure for the enumeration of coliforms from dairy products.	a "repair-detection" procedure consisting of pour plating of food samples with trypticase soy agar, followed by 1-h repair incubation at room temperature and subsequent overlay with violet red bile agar, was found to be an effective method for the detection of injuried and uninjuried coliforms from dairy products. this method was relatively less effective for the detection of coliforms in many semipreserved foods as compared with dairy products, but more effective than the most-probable-number m ...	1978	348110
the role of peyer's patches in the local immune response of rabbit ileum to live bacteria.		1978	351061
invasive escherichia coli.	the present evidence indicates that shigella-like pathogenicity is determined by a multiplacity of genes. although deliberate attempts have been made to confer invasive virulence on e. coli strain k12 by employing classical procedures of recombination with virulent s. flexneri donor strains, they have not yet been successful. while we should, theoretically, be able to achieve this, the practical problem of testing for pathogenicity precludes screening larger numbers of hybrid clones for the acqu ...	1978	351079
effects of dexamethasone on the responses of luteinizing hormone and testosterone to two injections of luteinizing hormone releasing hormone in young postpubertal bulls.	six young postpubertal bulls were studied in two experiments, 3 months apart. in experiment 1, three bulls received i.m. injections of dexamethasone (20 mg) and 5 h later these animals plus three control bulls received i.m. injections of luteinizing hormone releasing hormone (lh-rh, 250 microgram). in experiment 2, the controls from experiment 1 received dexamethasone and the treated animals from experiment 1 acted as controls for experiment 2. all bulls also received an i.m. injection of 250 mi ...	1978	351125
[conditions and factors determining the etiological structure of dysentery and its changes. report 1. epidemiological theory of etiological selectivity of the main (primary) pathways of infection and their differences in various nosological forms of dysentery].	the authors present the elaborated and formed epidemiological theory ("conformity theory") according to which the etiological structure of dysentery is determined by the etiological selectivity of the main (primary) waves of transmission of the infection differing in various nosological forms of dysentery. in grigoriev-shiga dysentery the domestic way of the spread of infection plays the main role, in flexner and newcastle dysentery--the water way, and in sonne dysentery--the food way (particula ...	1978	352042
[evaluation of hospitalization as an antiepidemic measure in dysentery].		1978	352046
[nature of inhibition of the activity of macromolecular antibodies].	the presence in the organism of an inhibitory factor expressing its activity under conditions of increased macromolecular globulins production (of m-immunoglobulins in particular) was established experimentally. the inhibitory factor depressed the avidity of the macromolecular antibodies; its appearance preceded reduction of the macromolecular protein level in the blood serum. the inhibitory effect of the blood serum in blood letting and vaccination with bacterial antigen is connected with the b ...	1978	352048
[the etiologic structure of dysentery in dagestan assr].		1978	352051
[experience with the diagnosis of dysentery in adults by determining antibodies to shigella in the saliva].	concentration of immunoglobulins and titres of antibodies to sh. sonnei, sh. flexneri and enteropathogenic e. coli 0111 was determined in mixed saliva and the blood serum of patients suffering from sonne dysentery, acute intestinal diseases of unknown etiology, and healthy individuals. the sum total immunoglobulin concentration in mixed saliva proved to be 53--81 times less than in the blood serum, but in the first substrate there was 53--75, and in the second--15% of immunoglobulin a. there pro ...	1978	352063
[effect of the transmission of a different type of mutation in the stra locus on the virulence of sh. flexneri].	the authors noted a different influence upon the virulence of sh. flexneri (determined by keratoconjunctival test) of transmission of different alleles of the stra-gene (a1, a2, a40, a60). there was revealed no correlation between the extent of the changes in virulence and the extent of capacity ot the limiting of suppression in donor strains.	1978	352064
[comparative study of the virulence of the shigella isolated from bacterial carriers and from acute dysentery patients].	the authors present the results of study of the virulence of shigellae isolated from carriers and patients suffering from acute dysentery, on a continuous culture of e1 and hep-2 cells. the virulence of shigellae isolated from carriers displayed no significant difference from the virulence of shigellae isolated from patients with a mild and moderately severe forms of dysentery. in the patient's organism shigellae were capable of retaining the initial virulence for a long time, despite the treatm ...	1978	352066
[characteristics of the changes in the intestines in acute dysentery depending on the type of the causative agent].		1978	354015
[current problems of dysentery].		1978	354019
[action of na-rna on infection in mice infected with shigella flexneri].	experiments were conducted on albino mice. experimentally induced dysentery infection proved to become aggravated under the effect of yeast na-rna expressed in the increase of the number of animals which fell ill and perished. this phenomenon proved to be based on the acceleration of reproduction of the causative agent, with a simultaneous selection of its virulent clones seen both in vitro and in vivo.	1978	354281
cervicofacial abcesses of unknown origin. a survey of eighty-one cases.	a survey of eighty-one patients with cervicofacial abscesses of unknown origin is presented. the salient clinical features and the treatment of the abscesses are described. mainly affected were children under 4 years of age, and the submandibular and submental regions were the most common sites of involvement. staphylococcus aureus was the predominant pathogenic organism, and epidemic strains were implicated in some cases. a high incidence of resistance to penicillin was noted. the nasal vestibu ...	1978	355964
the importance of the high spin/low spin equilibrium existing in cytochrome p-450 for the enzymatic mechanism.		1978	356064
epidemiology of common-source outbreaks of shigellosis in the united states, 1961-1975.	in 1961-1975, there were 72 foodborne and 38 waterborne outbreaks of shigellosis reported in the united states. foodborne outbreaks were most often caused by salads with contamination attributed to poor hygiene of a food handler. waterborne outbreaks most often involved semipublic water systems, and were usually the result of inadequate chlorination of water contaminated by human feces. in 110 common-source outbreaks, 16,541 persons were ill. the attack rate for both food- and waterborne shigell ...	1978	356596
aminoacyl-trna synthetases from yeast: generality of chemical proofreading in the prevention of misaminoacylation of trna.	the specificity of valyl-, phenylalanyl-, and tyrosyl-trna synthetases from yeast has been examined by a series of stringent tests designed to eliminate the possibility of artefactual interference. valyl-trna synthetase, as well as activating a number of amino acid analogues, will accept alanine, cysteine, isoleucine, and serine in addition to threonine as substrates for both atp-ppi exchange and transfer to some trnaval species. the transfer is not observed if atempts are made to isolate the ap ...	1978	356880
increase in the population of duodenal immunoglobulin a plasmocytes in axenic mice associated with different living or dead bacterial strains of intestinal origin.	various bacterial strains were tested for their ability to stimulate immunoglobulin a (iga) plasmocytes to populate the duodenal lamina propria in axenic mice. the mice were associated with the strains for at least 4 weeks. the strains inhabiting the conventional mouse intestine and belonging to the genera lactobacillus, streptococcus, eubacterium, actinobacillus, micrococcus, corynebacterium, and clostridium (including the extremely oxygen-sensitive ones) are only slightly or nonimmunogenic, wh ...	1978	357289
interaction between bacteriophage sf6 and shigella flexner.	the shigella flexneri phage sf6 has an isometric head with hexagonal symmetry 53nm in diameter. the noncontractile tails in 16 nm long and terminates with a base plate containing six spikes. sf6 is typical of the c phages in the morphological classification of bradley. phage sf6 processes alpha-1,3-endorhamnosidase activity as demonstrated by methylation and reducing end group sugar analyses of the products obtained on interaction with the o-polysaccharide chain of s.flexneri strains which have ...	1978	357756
[various aspects of competitive relationship between shigella and escherichia coli].	one of the aspects of antagonistic relations could be the competence of microorganisms for specific sites of attachement to the epithelium common for shigellae and some e. coli serological types; this was demonstrated on a model of shigella-induced keratoconjunctivitis and in experiments with the hep-2 cells infected with h3-glucose-labeled sh. flexneri 5a, with combined administration of the latter with e. coli 08 and 028. the data obtained emphasized the importance for the development of the i ...	1978	358685
heat-stable enterotoxin produced by shigella flexneri.	filtrates and ultrasonics extracts of shigella flexneri showed rapid permeability factor (pf) test and proved positive in suckling mice and ligated rabbit loop tests within 4 hr. delayed pf was not detected and the rabbit loop dilatation test read after 18 to 24 hr, the mouse pad oedema reaction, the test for elongation effect of cho cells were also negative. in the delayed pf test a strong "blanching" effect was observed. a filtrate of an ent-escherichia coli strain was positive only in the rap ...	1978	358769
unique features of heat-stable enterotoxin of shigella flexneri.	sephadex g-100 fractions of ultrasonic lysate of shigella felxneri were compared to the fractions of escherichia coli lysates of ent- , lt+ st+, lt+ and st+ strains. the range of molecular weight of s. flexneri st fractions was the same as that of e. coli lt fractions. rapid pf activity was associated with the st peak in the case of s. flexneri, and followed the lt activity in the e. coli (lt+ st+) fractions, and appeared in the same molecular weight range in the case of ent- e. coli lysate. cro ...	1978	358771
[effectiveness of biseptol in the overall treatment of acute sonne and flexner dysenteries].		1978	360614
[use of the fluorescent antibody method for establishing the etiology of discrete outbreaks of dysentery].		1978	362355
[sanitary conditions of water in public and private swimming pools, in the city of araraquara, sp, brazil].		1978	362510
structural studies of shigella flexneri o-antigens.	the structures of the o-antigens of all known serotypes and subserotypes of shigella flexneri have been reinvestigated. the results support the assumption that these antigens are composed of a basic tetrasaccharide repeating unit (1), to which alpha-d-glucopyranosyl and/or o-acetyl groups are attached at different positions. leads to 3)-beta-d-glcnacp-(1 leads to 2)-alpha-l-rhap-(1 leads to 2)-alpha-l-rhap-(1 leads to 3)-alpha-l-rhap-(1 leads to the immunological determinants responsible for o-f ...	1978	363425
on the metabolic characteristics of hybrids shigella flexneri x escherichia coli, devoid of their ability for intracellular multiplication in the epithelial cells. iv. growth characteristics in the presence of some tricarboxylic acid cycle intermediates.	the dynamics of avirulent xyl-str and xyl + hybrids sh. flexneri was investigated in minimal medium in the presence of some tricarboxylic acid cycle intermediates (succinate, malate, fumarate) and pyruvate. it was established that the hybrids with a replaced xyl-str or xyl-region show a considerably lower rate of multiplication in artificial media than the virulent recipient strains.	1978	364886
[quality of nutrient media according to indices of the cultivation process].		1978	364893
[immunoglobulins in acute dysentery].		1978	366890
[oral immunization with non-viable microorganisms or their antigens. 19. field trials with polyvalent enteritis-oralvaccines (author's transl)].		1978	367002
[the serotypes of shigella in catania (italy) during 1974--1976 (author's transl)].		1978	367296
[study of the mechanism of formation of protracted forms of dysentery].		1978	369138
[biological characteristics of transductants of shigella flexneri which have acquired different str-a-locus alleles].		1978	369250
agents affecting health of mother and child in a rural area of kenya. xi. antibodies against rotavirus in sera from children living in the machakos district of kenya.	207 sera from children under 5 years of age and living in the machakos district in kenya were tested in the complement fixation test for antibodies against rotavirus. two different antigens were used. the superiority of 'o' antigen over nebraska calf diarrhoea virus antigen was confirmed. after a fall to 29 percent in the 6-8 months age group, the percentage of children with antibodies quickly rises with age to 80 percent at the age of 24 months and to practically 100 percent at the age of 30 mo ...	1978	219569
mitochondrial reduced nicotinamide-adenine dinucleotide dehydrogenase is transmembranous [proceedings].		1978	217785
studies on an energy structure-function relationship of dehydrogenases. i. calorimetric investigations on the interaction of coenzyme fragments with horse liver alcohol dehydrogenase.		1978	204522
cyclic nucleotide phosphodiesterase. partial purification and characterization of a high affinity enzyme activity from human lung tissue.	part of the soluble cyclic nucleotide phosphodiesterase activity of crude human lung tissue can be attributed to a thermosensitive (37 degrees) enzyme with a high apparent affinity for both adenosine 3':5'-monophosphate (cyclic amp) and guanosine 3':5'-monophosphate (cyclic gmp). the enzyme can be partially purified by deae-sephadex chromatography. in the presence of 0.1 mm edta or ethylene glycol bis(beta-aminoethyl ether)n,n'-tetraacetic acid (egta), it is eluted from the column immediately be ...	1978	204635
the renin-angiotensin system.		1978	205167
solubilization and separation of delta5,3beta-hydroxysteroid dehydrogenase and 3-oxosteroid-delta4-delta5-isomerase from bovine adrenal cortex microsomes.	a physical separation of delta5,3beta-hydroxysteroid dehydrogenase and 3-oxosteroid delta4-delta5-isomerase solubilized from bovine adrenocortical microsomes is described for the first time. the solubilization as well as the separation was carried out with a mixture of a detergent: a substituted betaine (empigen bb/p) and sodium cholate. this latter detergent protects isomerase from complete inactivation by empigen and is necessary for the recovery of a significant amount of soluble isomerase. s ...	1978	205261
the distribution of the inherited hl 1 and r 67 antigens on rabbit serum high density lipoprotein (hdl) particles.	qualitative and quantitative analysis of the distribution of hl 1 antigen and r 67 antigen on high density lipoprotein (hdl) particles were conducted on six rabbit sera. the hl 1 antigen showed non-identity with a-i-containing hdl particles, and antiserum to hl 1 did not remove a-i-containing hdl particles. the r 67 antigen showed partial identity with a-i-containing hdl particles. antiserum to r 67 antigen removed 30--40% of a-i-containing hdl particles from the sera of animals which were heter ...	1978	205613
possible role of gamma-aminobutyric acid synthesis in the mechanism of dexamethasone feedback action.	specific inhibition of glutamic acid decarboxylase (gad, ec 4.1.1.15; the main enzyme involved in the synthesis of gamma-aminobutyric acid) by mercaptopropionic acid interferes with the effect of dexamethasone on both the resting and stress-induced secretion of acth. it is postulated that dexamethasone may, at least in part, inhibit the secretion of acth via the induction of gad, thereby raising the level of gamma-aminobutyric acid in the central nervous system.	1978	205622
the movement of plutonium, americium, and curium through the food chain.	the actinides, plutonium, americium and curium, are being produced in increasing quantites as the nuclear programme is expanded. as these alpha-particle-emitting elements are hazardous to man there is considerable concern about the movement of these elements through the environment; the uptake of these elements from soil into the plants is low, as is the gastrointestinal concentration factor. although there are complexing agents in the environment which have been shown to complex these elements ...	1978	205806
disseminated strongyloides stercoralis infection. association with ectopic acth syndrome and depressed cell-mediated immunity.	a patient with disseminated strongyloides stercoralis was evaluated to elucidate host factors that may have led to the development of this infection. the patient was found to have oat cell carcinoma with hypercortisolism produced by tumor adrenocorticotropic hormone. his serum contained a potent inhibitor of lymphocyte blastogenesis. this patient's high level of endogenous cortisol may have impaired lymphocyte function and thereby facilitated infection with s stercoralis.	1978	206218
susceptibility of human skeletal muscle culture to influenza virus infection. part 2. ultrastructural cytopathology.	cultured post-fused human skeletal muscle monolayers exposed to wsn influenza a virus were analyzed by scanning and transmission electron microscopy. at 12-14h post-inoculation (p.i.), affected mononuclear cells retracted from the cell surface, but remained anchored to the substrate by taut filar processes. retraction was accompanied by shortening of microvilli, appearance of hemispherical cytoplasmic protrusions and corrugation of the surface proper. these changes were more pronounced at 24 and ...	1978	206670
tumor antigen induction by the envelope-defective bryan strain of rous sarcoma viruses.	chicken, quail, and turkey cells were infected and/or transformed by various avian leukosis or sarcoma oncovirus (alsv) strains as well as by the envelope-defective bryan high-titer strain of rous sarcoma virus [bh-rsv(-)]. all fibroblast-transforming avian sarcoma viruses (asv), including bh-rsv(-), were able to induce the expression of the previously described avian tumor-specific cell-surface antigen(s) (tssa). thus tssa was group-specific for all tested transforming asv. since bh-rsv(-) is a ...	1978	206708
in vitro inhibition of rat brain atpase pnppase, and atp-32pi exchange by chlorinated-diphenyl ethanes and cyclodiene insecticides.		1978	207378
effects of substrates on tissue metabolic changes in the isolated rat heart during underperfusion and on release of lactate dehydrogenase and arrhythmias during reperfusion.	in langendorff-perfused rat hearts, the perfusion pressure was reduced from 100 cm h2o to 20 cm h2o for 30 minutes to produce a model of global ischemia with a residual oxygen uptake. the release of lactate dehydrogenase (ldh) and the occurrence of ventricular arrhythmias during reperfusion were dependent on the substrate. glucose-perfused hearts had the highest rates of glycolytic atp production (2.5 mumol/g per min) during ischemia with normal contents of tissue cyclic adenosine 3',5'-monophos ...	1978	207459
neonatal haematological abnormalities associated with maternal disease.		1978	207479
partial gonadotrophin-resistance in pseudohypoparathyroidism.	a patient with classical albright's pseudohypoparathyroidism was investigated because of oligomenorrhoea. hypo-oestrogenism was associated with elevated basal gonadotrophin values [mean basal serum lh and fsh were 272 +/- 84 (sd) ng/ml and 593 +/- 83 ng/ml, resplectively (normal less than or equal to 220 and less than or equal to 400, respectively)]. the response to gonadotrophin releasing hormone (gn-rh) was exaggerated, with maximal lh and fsh increments of 1688 and 458 ng/ml, respectively. th ...	1978	208340
[hyperlipidemia in rats with chronic renal failure].	the character of hyperlipidemia was studied in rats with chronic uremia induced by subtotal nephrectomy--5/6 of the renal tissue was removed. 13 to 30 weeks after this operation the blood serum cholesterol and phospholipid concentration almost doubled. hyperlipidemia was more pronounced in rats with high azotemia (blood urea nitrogen--bun). no elevation of serum tryglycerides occurred. total serum beta- and pre-beta-lipoproteins determined nephelometrically increased significantly only with the ...	1978	208685
the distribution of dietary plant sterols in serum lipoproteins and liver subcellular fractions of rats.	rats were fed plant sterols containing campesterol and beta-sitosterol in the differerent proportions, and their distribution in serum lipoproteins and in liver subcellular fractions was determined. in serum lipoproteins, the percentage as well as the concentration of plant sterols increased with the increase in the density of lipoproteins. thus, high density lipoprotein (hdl) contained the highest and very low density lipoprotein (vldl), the lowest. also, there were distinct differences in the ...	1978	209282
unanticipated prevalence of symptoms among dairy farmers in michigan and wisconsin.	adverse human health effects resulting from exposure to polychlorinated biphenyls (pbbs) were unknown until the accidental contamination of michigan dairy farm animal feed in 1973-1974. human exposure resulted from the consumption of contaminated meat, milk, dairy products, and eggs. in november 1976, the environmental sciences laboratory conducted comprehensive examinations of 933 farmers and residents in mighigan who were likely to have consumed farm products contaminated with pbb. a compariso ...	1978	209979
cytochrome oxidase activity of mitochondria in xenopus laevis previtellogenic oocytes.		1978	211159
enhanced chemotactic and phagocytic activities of leukocytes in psoriasis vulgaris.	leukocytes derived from the peripheral blood of psoriatic patients demonstrated an enhanced chemotactic response compared with leukocytes from healthy subjects. no significant difference was detected between the chemotactic response of leukocytes from patients with minimal or no skin involvement and those from patients with extensive lesions. psoriatic leukocytes also had a significantly higher capacity to engulf 125i labeled shigella flexneri than control leukocytes. it is postulated that a dec ...	1978	211169
evidence for the presence of serine-protease in the preparation of the very low density lipoproteins in human plasma.		1978	212123
comparison of interferon action in interferon resistant and sensitive l1210 cells.	translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...	1978	212514
transfer of duck cell dna sequences to the nucleus of 3t3 cells by rous sarcoma virus.	peking duck cell nuclear dna has no complementarity to rna of prague c rous sarcoma virus (rsv). upon infection of peking duck cells by prague c rsv, polynucleotide sequences complementary to peking duck cell nuclear dna can be detected in the high molecular weight rna from progeny peking duck cell passaged rsv (rsvpd) by rna.dna molecular hybridazation. when 3t3 cells are subsequently infected by rsvpd, polynucleotide sequences complementary to peking duck cell nuclear dna can be detected in th ...	1978	212741
age changes in collagen characteristics of bone and skin of a short-lived species of reptile.	decalcified bone collagen of older male garden lizards, calotes versicolor, was less susceptible to digestion by collagenase from clostridium histolyticum than that from younger individuals. in aged skin the percentage solubility and the soluble/insoluble collagen ratio decreased, with a concomitant rise in insoluble and total collagen. collagen/unit area increased with advancing age in both dorsal and ventral skin. these results from a non-mammalian poikilothermic vertebrate provide additional ...	1978	212937
effect of interferon on murine leukemia virus infection. iii. effect of interferon on msv-induced transformation.		1978	213891
increased spontaneous activity following substance p infusion into a10 dopaminergic area.		1978	214711
evaluation of oxidative phosphorylation in hearts from euthyroid, hypothyroid, and hyperthyroid rats.	the energy relationships between cytosolic and mitochondrial metabolism were studied in the hearts from euthyroid, hypothyroid, and hyperthyroid rats. isolated mitochondria showed high respiratory control ratios and impermeability to exogenous nadh. hypo- and hyperthyroidism, respectively, resulted in lower and higher contents of both cytochromes per mitochondrion and mitochondrial protein per gram of wet weight of heart without changes in the ratio of cytochrome c to cytochrome aa3. in isolated ...	1978	215035
opiate receptor agonists as modulators of gamma-aminobutyric acid turnover in the nucleus caudatus, globus pallidus and substantia nigra of the rat.	the injection of various doses of morphine, subcutaneously, or of beta-endorphin, intraventricularly, changes the turnover rate of gamma-aminobutyric acid (trgaba) in the substantia nigra, globus pallidus and nucleus caudatus. the trgaba decreases in n. caudatus but increases in globus pallidus and substantia nigra. these changes are dose related and can be inhibited by naltrexone. the increased trgaba in globus pallidus elicited by these opioid receptor agonists may be associated with catalepsy ...	1978	215744
construction of a recombinant plasmid composed of b. subtilis leucine genes and a b. subtilis (natto) plasmid: its use as cloning vehicle in b. subtilis 168.		1978	105237
[role of dysentery transmission factors in relation to the degree of environmental pollution].		1978	146641
[effectiveness of an agent of 8-hydroxyquinoline group in treatment of acute dysentery].		1978	148164
a fair deal for the handicapped.		1978	148882
the cardiomyopathy of the syrian hamster (strain bio 8262)--hypertrophic or dystrophic?	chemical as well as cytophotometric studies were carried out on myocardium of cardiomyopathic hamsters of strain bio 8262 and of healthy control hamsters of strain clac. our interest was to find out whether the cardiomyopathic hamsters suffer from hypertrophic cardiomyopathy or not. the heart muscle mass was only slightly increased in the older cardiomyopathic hamsters when compared with the controls. this increase was accompanied by an elevated content of total dns, rns and protein. furthermore ...	1978	148886
changes in immunological activity of rat lymphoid organs during pregnancy.	immune reactivity in lymhoid organs of rats during the last week of syngeneic (lewis: l x l) or allogeneic (females lewis x males wistar: l x w) pregnancy was compared with that found in non-pregnant animals. the thymus weight was slightly reduced and the response of thymic lymphocytes to phytohaemagglutinin and concanavalin a was slightly, but not significantly, elevated in pregnant rats. by contrast, the response of lymphoid cells from spleen and mesenteric lymph nodes to the mitogens was redu ...	1978	149623
effect of human immunoglobulin preparations on fc rosette formation between anti-d-coated erythrocytes and lymphocytes.	human immunoglobulin (ig) preparations were tested for their inhibitory effect on fc rosette formation between anti-d-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. both of the two biological activities ascribed to the sites in the fc portion of the igg molecules were found to be reduced in the pepsin-treated, as well as in the s-sulfonated ig preparations, as compared to the activities of the normal human ig preparation. in the plasmin-treated ig ...	1978	150144
[role of a water factor in seasonal fluctuations of the incidence of acute intestinal infections].		1978	151464
enhanced glycogen turnover in skeletal muscle of uremic rats--cause of uncontrolled actomyosin atpase?		1978	152057
[the triangular ligaments of the dog].		1978	152067
effects of 5,6-dihydroxytryptamine and 5,7-dihydroxytryptamine on the rat central nervous system after intraventricular or intracerebral application and on blood platelets in vitro.		1978	152083
irs, hew threaten triple-a bonds.		1978	152403
[biochemistry of myocardium taken at autopsy. preliminary report].	the findings after biochemical analysis of heart muscle taken at autopsy are given in this preliminary communication. human myosin is made up of two heavy sub-units and two light sub-units: it is similar to cardiac myosin found in other mammals, but is different in certain characteristics, particularly immunological ones. tropomyosin is made up of two different sub-units. the normal human heart contains 1 mg of collagen and 130 microgram of desoxyribonucleic acid (dna) per 100 mg of fresh tissue ...	1978	152617
inhibition of four human serine proteases by substituted benzamidines.	a series of substituted benzamidines has been examined for their inhibitory activity against the human serine proteases--trypsin, thrombin, plasmin, and c1s, a subunit of the first component of complement. the inhibition constants obtained for each enzyme were correlated with physical-chemical properties of the substituent group using the quantitative structure-activity relationship approach. this analysis indicated that plasmin and c1s are very similar in their interactions with substituted ben ...	1978	152812
[receptor adaptation of muscle spindles treated in different ways].	comparison of the grades of 60 sensitive muscle spindle terminals on two actions: gradual stretch of the muscle and short intensive tetanization of the muscle nerve, showed that, irrespective of the mode of action, the character of adaptation remains the smae in majority of units. the speed of receptors adaptation depends not on the specific of testing precedures, but, apparently, on the means of connection of the sensitive terminals with different types of intrafusal muscle fibers with differen ...	1978	153244
studies on human sexual development. vi. concentrations of unconjugated dehydroepiandrosterone, estradiol, and estriol in amniotic fluid throughout gestation.	concentrations of unconjugated dehydroepiandrosterone, estradiol, and estriol were measured in samples of amniotic fluid from uneventful pregnancies of 9-40 weeks conceptual age. there was no apparent influence of fetal sex upon the levels of these steroids. dehydroepiandrosterone concentrations rose slightly from 9-20 weeks, and then showed little further change. estradiol concentrations declined slightly from 9-20 weeks; after 32 weeks gestation, there was a 2-fold rise to term. estriol levels ...	1978	162521
[note about the biology of cuterebra apicalis (guérin, 1829/38) (diptera-cuterebridae) (author's transl)].	this note reports the parasitism by cuterebra apicalis guérin (1829/1838) on the rodents oryzomys eliurus and calomys callosus collected in the north of formosa county, goiás state. the infested animals were kept in the laboratory to allow observations on the development of the parasite.	1978	108773
macaca assamensis as a new host for experimental plasmodium knowlesi infection.		1978	108217
limitations of aeruginocine typing of ps. aeruginosa as an epidemiological marker.		1978	108218
an enzyme-linked immunosorbent assay (elisa) for detecting chicken anti-reovirus antibody at high sensitivity.	an enzyme-linked immunosorbent assay (elisa) with high sensitivity was developed for use in the avian system. anti-reovirus antibody produced in chickens against the isolants s1133, umi-203, reo-25, and winterfield were detected with this method at high titers (up to 1:14,000).	1978	107949
immunologic functions and in vitro activation of cultured macrophage tumor lines.	five murine monocyte of macrophage tumor lines adapted to culture were characterized for differentiated properties. they ingested zymosan and latex beads, bore receptors for immunoglobulin and complement, synthesized lysozyme (most of which was secreted), and produced granulocyte colony-stimulating activity, either spontaneously or inducibly. some of the lines also mediated phagocytosis and exocytosis of red blood cells (rbc) and lysis of tumor targets, dependent on the presence of specific anti ...	1978	107454
[preparation of extracellular ribonuclease from bacillus subtilis].	the paper describes a method for isolating alkaline ribonuclease from the culture liquid bacillus subtilis kp 349 which involved: submerged cultivation of the producer on complex and synthetic nutrient media with optimized rnase activity, acid treatment of the total culture liquid, and filtration through perlite. further treatment may include either spray drying of the culture liquid filtrate or its concentration in a vacuum evaporator, dialysis of the concentrate against distilled water, and d ...	1978	107517
[induction of macrophage activation with bacterial products for potentiation of resistance to some chronic infections].	adult mice of the consanguine a2g strain received two intraperitoneal inoculations of 0.5 mg listeria monocytogenes phospholipid extract at 30 days interval. in the treated animals and the controls, the capacity to develop a humoral immune response was tested 24 hours after the second inoculation, following antigenic stimulus with sheep red blood cells; phagocytizing in vitro of labelled germs by peritoneal macrophages and the response of lymphocytes to mitogenic and allogenic stimuli were likew ...	1978	107569
enteric infections in singapore with special reference to typhoid.	a review of the epidemiological features of the more important enteric infections in singapore was given. enteric fevers (typhoid and paratyphoid), salmonella gastroenteritis and shigellosis remained endemic at a rather constant level in spite of vast improvement in environmental sanitation, but amoebic dysentery showed marked decline. vibrio parahaemolyticus is an important cause of food poisoning since it was first reported in 1973. el tor cholera is believed to be introduced through regional ...	1978	107597
[some notes on the specifity of the fluorescence histochemical demonstration of gaba (author's transl)].	the distribution of the gaba in the purkinje cells of the rat cerebellum was demonstrated by means of modified fluorescence histochemical method according to wolman (1971). three types of purkinje cells, with respect to their fluorescence intensity and gaba distribution, were evident. the gaba-fluorescence was strikingly by pharmacological pretreatment. isonicotinic acid hydrazide, penicillamine and chlorpromazine cause a granulation and marked reduction of the fluorescence compound, being norma ...	1978	105559
case report: intestinal clearance of calcium and protein in waldenstrom's macroglobulinemia.	a 63-year-old man with waldenstrom's macroglobulinemia had severe steatorrhea, marked protein-losing enteropathy, and excessive endogenous fecal calcium clearance. the malabsorption and protein loss resulted in weight loss and hypoalbuminemia. in contrast, the striking enteric calcium loss was completely compensated by an increase in calcium absorption resulting in a positive calcium balance.	1978	105640
on the sites of the negative and positive feedback actions of estradiol in the control of gonadotropin secretion in the rhesus monkey.	ovariectomized rhesus monkeys bearing hypothalamic lesions which had abolished endogenous lhrh production, as evidenced by a profound reduction in gonadotropin secretion, but in which lh and fsh secretion was reestablished by a chronic intermittent iv infusion of synthetic lhrh (1 microgram/min for 6 min every hour) were used to investigate the sites of the negative and positive feedback actions of estradiol in the control of gonadotropin secretion. the administration of estradiol to such animal ...	1978	105873
thyrotropin response to thyrotropin-releasing hormone in the euthyroid rat: dose-response, time course, and demonstration of partial refractoriness to a second dose of thyrotropin-releasing hormone.		1978	105883
food toxins and their implication in human health.		1978	105997
[lithium and pregnancy (author's transl)].	the problem has been considered of the action of lithium salts on the progress of pregnancy and on the product of the conception. lithium can bring about serious troubles in morphogenesis in invertebrate animals. the results obtained in mammals in laboratory experiments differ from species to species but it seems that these animals can be given about 8 to 9 times the levels of lithium that are used in man without causing teratogenic effects. a statistical review of the children born to human mot ...	1978	106083
the metabolism and disposition of 3,4,4'-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (m. mulatta).		1978	106490
[calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings].		1978	106573
[antibody induced phase variation in pseudomonas aeruginosa (author's transl)].	to extend the flagella specific h antigenic schema of p. aeruginosa (ansorg, 1978), investigations are carried out to reveal phase variation in this species as in salmonella or arizona. with conventional methods, i.e. examination of single colonies after plating the cultures on standard nutrient agar or the phase reversal techniques of craigie (1931) and gard (1938) by adding homologous anti-oh-serum of different amounts in semisolid agar medium, no change of the flagellar antigens of various p. ...	1978	106580