Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
overcoming of endotoxin--mediated immunosuppression by bordetella pertussis. 19724339277
long-term preservation of bordetella pertussis.viability of bordetella pertussis was preserved when glycerol broth suspensions were quick frozen and stored at -70 c for as long as 45 months.19724333895
increased protein synthesis of spleen cells after injection of bordetella pertussis into mice. 19724341374
efficacy of pertussis vaccines: a brighter horizon.a study of pertussis infections in 186 children under 11 years of age in the manchester region during 1969-71 suggests that recently-manufactured vaccines have been more effective than those made before 1967. the earlier vaccines were effective mainly against the serotypes of bordetella pertussis possessing antigen 2, while those made from 1967 are more nearly equal in their effectiveness against thedi fferent serotypes. a booster dose of the earlier vaccines did not prevent infection with type ...19724341645
the influence of the route of immunization on the protection of mice infected intracerebrally with bordetella pertussis.the development of immunity in mice to bordetella pertussis induced by intracerebral, intravenous or intraperitoneal vaccination was analysed in terms of the viable bacteria in the brain after intracerebral challenge, the serum antibodies, and protection against the sublethal infection of the lung that follows intranasal inoculation.a vaccine introduced intracerebrally was five to ten times more effective than that given intraperitoneally or intravenously, as measured for each route by the amoun ...19724341998
selective medium for the isolation of bordetella pertussis and parapertussis. 19724342612
effect of lymphocytosis-promoting factor of bordetella pertussis on the immune response. i. suppression of cellular hypersensitivity reactions. 19724342865
effect of lymphocytosis-promoting factor of bordetella pertussis on the immune response. ii. adjuvant effect for the production of reaginic antibody in the rat. 19724342866
[influence of bordetella pertussis on the lymphatic tissue of mice. vii. studies on the relationships between the various biological effects induced by bordetella pertussis]. 19724343422
an electron-microscope study of intracerebral infection of mice with low-virulence bordetella pertussis. 19724343581
sensitization of mice by inhalation of antigen after infection with bordetella pertussis.intranasal infection of mice with bordetella pertussis or injection of pertussis vaccine previous to administration of an albumin aerosol augments sensitivity toward albumin. sensitization was demonstrated by provocation of anaphylactic reactions following intravenous injection of antigen.19724343934
immunization of mice against encephalomyocarditis virus. ii. intraperitoneal and respiratory immunization with ultraviolet-inactivated vaccine: effect of bordetella pertussis extract on the immune response.mice were immunized by intraperitoneal (ip) or respiratory administration of ultraviolet-inactivated virus alone or with bordetella pertussis extract (bpe) as an adjuvant. the effect of immunization was tested by determination of antibody titers and by survival of a lethal challenge with 200 ld(50) of a virulent (large-plaque variant) strain of emc virus. for plain vaccine the ip 50% effective dose (ed(50)) was 37 hemagglutination units (hau; ca. 4 x 10(6) plaque-forming unit equivalents); with ...19724344027
time relationships between injection of antigen and adjuvant. 3. adjuvancy of bordetella pertussis given at various times after the primary antigenic stimulus.the adjuvant activity of bordetella pertussis was investigated, both at the cellular and humoral levels, when the bacterial adjuvant was given at various times after the primary antigenic stimulus of both 2 x 10(7) (suboptimal dose) and 4 x 10(8) (optimal dose) of sheep erythrocytes. in all experiments, both adjuvant and sheep erythrocytes were administered by the intraperitoneal route. adjuvant activity was measured on the basis of the early and late phases of the primary response and on the de ...19724344394
leucocytosis-promoting factor of bordetella pertussis. i. purification and characterization.the leucocytosis-promoting factor was purified from the supernatant fluid of spent cultures of bordetella pertussis on solid medium. after precipitation at 67% saturation of ammonium sulfate, the leucocytosis-promoting factor was extracted with a 1.0 m nacl solution. purification was accomplished by starch block electrophoresis and sucrose density gradient centrifugation. the purified preparation contained a high leucocytosis-promoting activity, and as small an amount as 0.04 mug of protein indu ...19724344632
distribution of labeled lymph node cells in mice during the lymphocytosis induced by bordetella pertussis.the mechanism by which bordetella pertussis organisms and their products induce lymphocytosis in mice was analyzed in terms of the localization of syngeneic cr-51-labeled lymph node cells. labeled lymphoid cells incubated in vitro with the supernatant of b. pertussis cultures and then injected intravenously into normal recipients, or labeled cells injected into pertussis-treated recipients were unable to "home" to lymphoid organs but persisted for long periods in the blood. in animals "equipped" ...19724345107
the pathology and immunology of bordetella pertussis infection. 19724345765
an electron-microscopic study of intracerebral infection of mice with low-virulence bordetella pertussis. 19724345768
passive protection of mice against intracerebral infections with bordetella pertussis.the passive protection of mice against an intracerebral infection with bordetella pertussis, by antiserum introduced directly into the brain with the infecting organisms, was compared with the protection afforded by intraperitoneal antiserum. the antibody effective by the intracerebral route is that which is adsorbed onto the infecting organisms, although it does not affect the viability of the organisms in vitro in the absence of complement.passive protection against organisms introduced intrac ...19724346011
areexamination of phase iv bordetella pertussis. 19724346447
[bordetella pertussis spheroplasts. 4. the protective, histamine-sensitizing and toxic action of spheroplasts and spheroplast cell walls]. 19724122376
fatal anaphylaxis-like reaction induced by yeast mannans in nonsensitized mice.some yeast mannans increased vascular permeability and caused anaphylaxis-like reactions, fatal in some cases, in nonsensitized cfw mice. in swr mice deficient in the complement system component c5, anaphylactic shock did not develop after the injection of mannans but was readily induced by goat serum after the mice had been sensitized with bordetella pertussis and goat serum. the observed biological activity of the yeast mannans appears to depend upon the alpha(1 --> 2) and alpha(1 --> 6) linka ...19724117879
[serology of bordetella pertussis. ii. preparation of ultrasonic extract of b. pertussis and its column chromatography on deae-cellulose]. 19724145108
[bordetella pertussis spheroplasts. 3. isolation and chemical analysis of spheroplast cell walls]. 19724146136
on the mechanism of the adjuvant effect of bordetella pertussis vaccine. 19725011091
[study of the lymphocytosis-stimulating factor of bordetella pertussis]. 19725047734
interaction of bordetella pertussis vaccine treatment and lymphocyte choriomeningitis virus infection in mice. 19725076340
[bordetella pertussis spheroplasts. 1. cultivation of spheroplasts]. 19724402415
[bordetella pertussis spheroplasts. 2. the protective action of spheroplasts and spheroplast fractions]. 19724402416
hematopoietic changes in nmri mice after the intravenous and subcutaneous injection of bordetella pertussis vaccine. 19724654223
detection of bordetella pertussis antibodies in human sera by complement-fixation and immunofluorescence.the complement-fixation test, as commonly used in the diagnosis of viral infections, was studied for its possible application to the diagnosis of whooping cough and the detection of antibody following pertussis vaccination. the results were compared with those obtained in parallel immunofluorescence tests. cfts were performed on sera from 41 patients with whooping cough (bordetella pertussis isolated), 125 vaccinated persons, and 618 controls; parallel tests by if were made on sera from 24 cases ...19724335341
[influence of bordetella pertussis on the lymphatic tissue of mice. vi. further studies regarding the influence of bordetella pertussis on the immunological memory response]. 19714335600
effects of epinephrine, norepinephrine and isoproterenol against challenge in bordetella pertussis-treated and beta-adrenergic blocked mice. 19714397558
non-appearance of splenomegaly after injection of killed bordetella pertussis cells into aged mice. 19715127889
mechanism of hypersensitivity to histamine of rats treated with bordetella pertussis vaccine. 19715314273
bordetella pertussis as a beta-adrenergic blocking agent. 19714149878
the effect of histamine on mice vaccinated with bordetella pertussis. 19714101824
disruption of bordetella pertussis in the ribi cell fractionator. 2. effect of different suspending media. 19714107161
the effect of bordetella pertussis vaccine on epinephrine induced hyperglycemia in rats. 19714111421
specific secondary biological properties of purified rabbit immunoglobulin m and immunoglobulin g antibodies to brucella abortus and bordetella pertussis.rabbit immunoglobulin (ig)m and igg antibodies to brucella abortus and bordetella pertussis were isolated as purified products and their specific secondary biological activities were compared. igm antibodies were found to be more active than igg proteins in inducing agglutination and sensitization of b. abortus for the complement-dependent bactericidal effect and in inhibiting b. pertussis-induced lymphocytosis in the mouse. igm and igg antibodies were found to be equally effective in inducing a ...19714343404
international collaborative studies on the pertussis vaccine potency assay. part played by the challenge in the mouse-protection test.because of wide variations in the methods used to assay the potency of pertussis vaccine, the effect of the type of challenge used in the mouse-protection test was studied. eight laboratories took part in a collaborative investigation and the potencies of 4 pairs of vaccines were estimated. two methods were used, a "local method" using local strains and procedures for challenge, and a "study method" using a distributed strain and a specified procedure. for both methods the challenge level (mouse ...19714334408
the reactivity of aged mice to bordetella pertussis as an immunological adjuvant. 19714339715
[immunochemical study of the antigenic structure of bordetella genus bacteria. i. immunoelectrophoretic analysis of the antigenic structure of different strains of bordetella pertussis and their biological properties]. 19714328259
[isolation of agglutinogen complex from bordetella pertussis of various serological types]. 19714328260
stimulation of non-specific resistance by heterologous endotoxins and experimental immunity to bordetella pertussis in mice. 19714328408
[epidemiological surveillance of bordetella pertussis and parapertussis sensitivity to antibiotics]. 19714328643
the association of viruses with clinical pertussis.this study describes the results of attempts to grow viruses from per-nasal swabs taken from 136 children with clinical pertussis.altogether 37 strains of a variety of different viruses were isolated. adenovirus was the most frequent, making up 30% of the total. besides these, herpes simplex, measles, influenza a2, influenza b, mumps, poliovirus and respiratory syncytial virus were detected.bordetella pertussis was isolated from 22% of the cases.it appears that a pertussis-like syndrome can be c ...19714328794
[pathogenesis of experimental allergic encephalomyelitis caused by sensitization with bordetella pertussis combined with cerebral tissue]. 19714329604
disruption of bordetella pertussis in the ribi cell fractionator. 1. effect of different pressures. 19714329814
occasional sporadic cases of whooping cough-like syndrome associated with adenoviral infection: contrast with epidemic whooping cough caused by bordetella pertussis. 19714329891
purified k-agglutinogen of bordetella pertussis and its properties. 19714330023
[antigens of bordetella pertussis and their repercussion in immunization programs against whooping cough]. 19714330706
aggregation of platelets of normal and bordetella pertussis vaccinated mice by atp, adp, and sodium fluoride. 19714331634
[effects of bordetella pertussis injection in newborn mice]. 19714332490
studies on the leukocytopenia due to acute effects of supernatant fluids of bordetella pertussis cultures. 19714322686
enhancing effect of bordetella pertussis and propranolol on experimental immune hemolytic anemia. 19714323020
lienotoxicity of bordetella pertussis in mice. 19714323399
the occurrence of bordetella pertussis serotypes in australia, 1950-1970. 19714324689
[characteristics of bordetella pertussis soluble antigens]. 19714325870
experimental acute pulmonary edema in the rat. effect of bordetella pertussis vaccine on ozone mortality. 19714326836
studies on lymphocytes 18. mechanism of lymphocytosis induced by supernatant fluids of bordetella pertussis cultures. 19714326837
antigens of bordetella pertussis v. separation of agglutinogen 1 and mouse-protective antigen.agglutinogen 1 of bordetella pertussis strain 353/z (serotype 1) was separated from protective antigen and histamine-sensitizing factor by starch-block electrophoresis. most of the agglutinogen 1 migrated towards the cathode in starch-block electrophoresis, although some remained near the origin. fractions containing most of the agglutinogen 1 were free of detectable mouse-protecting or histamine-sensitizing activities. agglutinogen 1 from a serotype 1, 3 b. pertussis strain (j20) migrated simil ...197116557960
variable adjuvant activity of bordetella pertussis with respect to the primary and secondary immunization of mice.we carried out a study on the adjuvant effect of bordetella pertussis vaccine on the primary and secondary immune responses of the mouse to sheep erythrocytes, quantitating antibody-producing spleen cells and serum antibody. the simultaneous injection of sheep erythrocytes and b. pertussis, when compared to immunization with sheep red blood cells alone, resulted in an increased and prolonged multiplication of antibody-forming spleen cells. the adjuvant effect was also documented by increased pro ...197016557724
influence of bordetella pertussis on adenosine diphosphate-induced aggregation of mouse platelets.several lines of evidence support the concept that bordetella pertussis-induced histamine hypersensitivity in mice represents a malfunction in beta-adrenergic receptors of the autonomic nervous system. in this study mouse platelets were used as an in vitro test for such receptor dysfunction. it was found, to our knowledge for the first time, that platelets of normal mice were subject to the aggregative action of adenosine diphosphate (adp) with the response pattern resembling that reported for c ...197016557829
time relationships between injection of antigen and adjuvant i. adjuvancy of bordetella pertussis given at various times before the primary antigenic stimulus.the adjuvant activity of bordetella pertussis was investigated, both at the cellular and humoral levels, when the bacterial adjuvant was administered at various times before the primary antigenic stimulus of both 8 x 10(6) and 4 x 10(8) sheep erythrocytes. in all experiments, both adjuvant and erythrocyte antigen were given intraperitoneally. adjuvant activity was measured on the basis of the primary immune response and on the degree of priming for the secondary immune reaction. a maximal effect ...197016557882
bordetella pertussis serotypes in the united states.[this corrects the article on p. 620 in vol. 18.].197016349881
[bacteriology of whooping cough. ii. determination of the major agglutinant factors in bordetella pertussis samples isolated in rio de janeiro]. 19704327251
studies on the leukocytosis and lymphocytosis induced by bordetella pertussis. 3. the distribution of transfused lymphocytes in pertussis-treated and normal mice.peripheral blood lymphocytes were isolated from normal mice and mice undergoing pertussis-induced lymphocytosis. after labeling in vitro with tritiated uridine the cells were transfused into normal or pertussis-treated mice. it was found that the lymphocytes from pertussis-treated mice entered the lymph nodes of both normal mice and pertussis-treated mice to a significantly lesser extent than did normal lymphocytes which had been transfused into either class of recipient. in addition, an interde ...19704323778
a simple chemically defined medium for the production of phase i bordetella pertussis. 19704324651
reduced adjuvant activity of bordetella pertussis vaccine in mice after priming with an immunogenic threshold dose. 19704318029
antigen-sensitive spleen cells and the adjuvant activity of bordetella pertussis. 19704319471
diagnosis of whooping cough: comparison of serological tests with isolation of bordetella pertussis. a combined scottish study.antibody titres for bordetella pertussis in paired sera from 223 children with suspected whooping cough showed good correlation by complement fixation and agglutination techniques. the patient's age was related to serological responses and in a different way to b. pertussis isolations: in 73 children under 6 months of age b. pertussis was isolated from nasopharyngeal secretions in 42% and serological findings were positive in 19%; in 11 patients over 1 year of age serological tests were positive ...19704321207
modified state of susceptibility to histamine in mice treated with bordetella pertussis during the neonatal period. 19704321232
the partial purification and some biological activities of histamine sensitizing factor from bordetella pertussis. 19704321640
[bordetella pertussis as an immunological adjuvant]. 19704311955
modification of subsequent intracerebral infection with bordetella pertussis by previous local brain irradiation. 19704312350
a reaginic type of antibody stimulated by extracts of bordetella pertussis in inbred strains of mice. 19704312873
attempts at isolation of lymphocytosis-producing factor from supernatant fluids of bordetella pertussis cultures. 19704313155
chemical and biological properties of the purified o antigen of bordetella pertussis. 19704313572
use of glutamic acid to supplement fluid medium for cultivation of bordetella pertussis.the amino acid consumption by bordetella pertussis growing in broth containing casein hydrolysate was examined. serine, proline, alanine, glycine, aspartate, and glutamate were rapidly consumed, in a manner which suggested that they supplied the energy requirements of the organism; exhaustion of the energy source appeared to be the main factor limiting the yield of cells. there was no correlation between the utilization of individual amino acids and the phase of growth; uptake appeared to depend ...19704314842
conversion of atp by mouse lung preparations and by an extract of bordetella pertussis. 19704315255
studies on the ultrastructure of bordetella pertussis. i. morphology, origin, and biological activity of structures present in the extracellular fluid of liquid cultures of bordetella pertussis.two distinct particles have been recognized in the extracellular fluid of b. pertussis cultures. both appeared to arise from the surface (cell wall) of the organism. one of these, a membranous particle, seemed to derive from long projections on the organism composed of the outer membrane of the cell wall. the second particle, a fine filament, was not readily comparable with any previously described bacterial structure. the two particles could be separated from each other by gradient centrifugati ...19704315895
effects of the lymphocytosis-promoting factor from bordetella pertussis on the function and potentiality of lymphocytes. i. effect on the ability of lymphocytes to recirculate in the body. 19704317540
enhancement of intracerebral infection of mice with bordetella pertussis. 19704317688
isolation of bordetella pertussis from pernasal swabs stored in stuart's transport medium. 19704317689
intracerebral infection of mice with high-virulence and low-virulence strains of bordetella pertussis. 19704317690
eosinophil leukocyte responses and hypersensitivity reactions in the bordetella pertussis-treated mouse. 19704318636
[immunologically and biologically active cellular components of bordetella pertussis]. 19704318659
partial purification and some properties of the leukocytosis-promoting material from bordetella pertussis. 19704099421
reduced effect of epinephrine on circulating eosinophils in asthma and after beta-adrenergic blockade or bordetella pertussis vaccine. with a note on eosinopenia after methacholine. 19705272075
mechanism of sensitization to the lethal effect of histamine in rats induced by bordetella pertussis vaccine. 19705311429
the effect of bordetella pertussis vaccine and adrenal hormones on 5-hydroxytryptamine level in rat tissues. 19705469522
[on tissue reactivity during experimental infection and immunization with bordetella pertussis]. 19705521124
the sensitizing action of bordetella pertussis vaccine. 19704391480
reduced adjuvant activity of bordetella pertussis on the secondary immune response of mice evoked by an immunogenic threshold dose of sheep erythrocytes. 19694319348
active immunotherapy in treatment of acute leukaemia.active non-specific immunotherapy has been used to prolong remissions in acute lymphoblastic leukaemia. the series reported here used bordetella pertussis vaccine in a controlle trial after intensive chemotherapy. possibly immunotherapy delayed the onset of relapse in the treated patients, but no long-term remissions were obtained. further work is needed to establish the role of immunotherapy in general, and the use of b. pertussis vaccine in particular, in the treatment of acute leukaemia.19694901340
the effect of bordetella pertussis vaccine on the development of experimental thyroiditis in rats immunized by the intra-lymph node route or into a hind footpad. 19694902606
advantages of aluminium hydroxide adsorbed combined diphtheria, tetanus, and pertussis vaccines for the immunization of infants.three combined triple antigen vaccines were used to inoculate infants receiving primary immunization at 3 to 6 months of age. laboratory potency and toxicity tests and clinical evaluation again showed that the mouse weight gain test is able to predict which vaccines will give reactions in children. the addition of aluminium hydroxide to the vaccine both increased potency and reduced the tendency to cause reactions. assays on sera showed that almost all children produced agglutinins to bordetella ...19695774314
the influence of bordetella pertussis on the preparation of mouse spleens for the secondary immune response. 19695796124
effects of the lymphocytosis-promoting factor of bordetella pertussis on antibody production in mice. 19695307011
the influence of environment on the mouse weight-gain test for estimating the toxicity of bordetella pertussis vaccines. 19695379952
Refresh
firstprev
...9192939495969798
nextlast
Displaying items 9101 - 9200 of 9771