Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| experimental pulmonary aspergillosis in sensitized rabbits. | 1977 | 142913 | |
| enzymatic release of iron from sideramines in fungi. nadh:sideramine oxidoreductase in neurospora crassa. | young mycelia of the fungus neurospora crassa contain a soluble nadh-linked sideramine reductase, which may be responsible for liberating iron in vivo from accumulated sideramines during iron-deficient cultivation. the enzymes can be assayed using a soluble supernatant fraction, edta, and an atmosphere of pure nitrogen. the enzyme is stable without loss of activity up to 45 degrees c and has an optimum of activity at ph 7.0. besides coprogen (km = 100 micrometer, v=2.8 nmol/min per mg protein), ... | 1977 | 144535 |
| circulating immune complexes and activation of the complement sequence in acute allergic bronchopulmonary aspergillosis. | a 13-yr-old asthmatic girl with allergic bronchopulmonary aspergillosis (abpa) exhibited eosinophilia, ige hypergammaglobulinemia, serum precipitins to aspergillus, a dual skin reaction to aspergillus fumigatus, and positive, lymphocyte transformation in vitro in response to stimulation with aspergillus fumigatus antigen. the acute phase of the disease was characterized by an increase in blood eosinophilia, a rise in serum ige, circulating immune complexes, and evidence of activation of the comp ... | 1977 | 144747 |
| relationship between proteolytic activity of aspergillus fumigatus and the fungus invasiveness of mouse brain. | 1977 | 340955 | |
| natural occurrence of aspergillus fumigatus in cane sugar mills. | the environmental distribution of aspergillus fumigatus in 2 cane-sugar mills and one paper factory in northern india is compared with 2 localities in delhi. the preponderance of the species at the u.d. sugar mills, shamli, was contrary to its low prevalence in the university of delhi campus and at subzimandi, the vegetable and fruit market of delhi. aspergillus fumigatus accounted for 42.5% of the total aerial fungal colony counts recorded in the shamli mills as against 2% in delhi. the predomi ... | 1977 | 341368 |
| [experimental studies in animals on the influence of fluocortin butylester on the course of generalized infections (author's transl)]. | the influence of butyl 6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxo-1,4-pregnadien-21-oate (fluocortin butylester, vaspit), a new corticosteroidal compound with a marked dissociation between local antiinflammatory and systemic action, upon resistance against infections was studied in experimental bacterial and fungal infections in mice. the results of the experiments showed, that fluocortin butylester, even after repeated s.c. or oral administration of dosages up to 100 mg/kg did not d ... | 1977 | 341900 |
| treatment with antifungal vaccines. | 1977 | 342190 | |
| "aspergillus fumigatus"--a pathogen and allergen. | aspergillus fumigatus is being increasingly recognised as causing various pathological conditions in man, animals and birds. in man the use of antibiotics has increased the importance of fungi in various clinical situations as opportunistic infective agents. in man, cavities in the lung are often (20 per cent) colonised by aspergillus species, nearly always a. fumigatus. the mycetoma so formed can be specifically diagnosed by finding precipitating antibodies to a. fumigatus in the serum. in an a ... | 1977 | 345783 |
| [studies on the toxin of aspergillus fumigatus. viii. biological properties of asp-hemolysin (author's transl)]. | 1977 | 342741 | |
| [apropos of a case of invasive pulmonary aspergillosis with subadjacent aspergilloma]. | 1977 | 343198 | |
| cell-pool tryptophan levels during ergot alkaloid formation in aspergillus fumigatus. | 1977 | 340382 | |
| mycotoxins produced by aspergillus fumigatus isolated from silage. | results are presented which show that aspergillus fumigatus was one of the predominant fungi contaminating moldy silage. growth of a. fumigatus on silage appeared to depend on a preliminary aerobic fermentation by other natural microflora in silage. the clavine alkaloid, fumigaclavine a, and a new clavine alkaloid designated fumigaclavine c were produced by a. fumigatus. the ld50 of fumigaclavine c was approximately 150 mg/kg oral dose in day-old cockerels. | 1977 | 350117 |
| detection of aspergillus fumigatus precipitins: a comparison of counter immunoelectrophoresis and double diffusion. | a counter immunoelectrophoresis method was compared with a double diffusion test for detecting aspergillus fumigatus antibodies. of 70 patients, 23 gave positive results in both tests and the remainder gave negative results. fifteen patients with proven aspergillosis gave positive results in both tests. | 1977 | 404338 |
| the diagnosis of aspergillus fumigatus infection of the nasal chambers of the dog with particular reference to the value of the double diffusion test. | 1977 | 404470 | |
| experimental aspergillosis in buffaloes: histopathological, histochemical and serological studies. | 1977 | 405583 | |
| modified indirect fluorescent-antibody test for aspergillosis. | diffuse fluorescence in an indirect fluorescent-antibody test for antibody to aspergillus fumigatus was eliminated by using germlings, rather than hyphae, as antigen. the modified method yielded diagnostic titers larger than or equal to 1:32 in 24 of 25 known cases, was highly specific, and showed good correlation with clinical status and results of immunodiffusion. this technique, which uses the germling antigen, inactivation of test serum at 59 +/- 1 degrees c, and anti-immunoglobulin g conjug ... | 1977 | 408374 |
| variability of extracts used in immunoprecipitin tests. | immunodiffusion reactions of several different commercial fungal extracts from organisms were compared to those obtained from patients' environments. sera were obtained from patients suspected of having hypersensitivity lung disease (hld). there was a difference in reactivity among the sources of the antigen and in some lots of antigen from the same commercial supplier. the results demonstrate a wide variation in the reactivity of different antigenic extracts and emphasize the need for uniform s ... | 1977 | 409751 |
| opportunistic mycotic osteomyelitis: bone infections due to aspergillus and candida species. | 1977 | 411015 | |
| clinical and therapeutic significance of patterns of allergic reactions of the lungs to extrinsic agents: the 1977 j. burns amberson lecture. | 1977 | 411403 | |
| a comparative investigation of the bactericidal and fungicidal effects of three phenolic disinfectants. | 1977 | 412825 | |
| sensitivity to 5-fluorocytosine and virulence for mice of some human isolates of aspergillus. | the sensitivity of 5-fluorocytosine (5-fc) and the virulence for mice was assessed for 16 human isolates of aspergillus: a. fumigatus 2, a. niger 7, a. flavus 4, a. terreus 2 and a. conicus (a. restrictus group) 1. fourteen strains were recovered from ear exsudates, 1 from sputum and 1 from the pus of mastoid cells of an autopsy case with meningeal and cerebral involvement. nine of them, which included strains of a. fumigatus and a. niger were sensitive to 5-fc (m.i.c. less than or equal to 6.4 ... | 1977 | 413042 |
| [mycologic study of the bronchial aspirates of patients with chronic lung diseases]. | 1977 | 414489 | |
| bilateral endogenous endophthalmitis successfully treated with 5-fluorocytosine. | 1977 | 346120 | |
| fungal antigens as a source of sensitization and respiratory disease in scottish maltworkers. | mycological and serological studies were carried out as part of a survey of respiratory disease in scottish maltworkers. 70% of stained sputum smears from 574 workers showed the presence of higher plant cells and/or myclelia, and the spores of common environmental fungi. penicillium spp. (90%), rhizopus stolonifer (48%) and yeasts (53%) were the dominant fungi in 699 sputum cultures, and showed a similar proportional distribution in 327 samples of grain, malt, culms and dusts from fifty-six malt ... | 1977 | 589785 |
| fungus infection of ear. | of 2,632 patients seeking medical help for symptoms pertaining to the ear, 1,264 were clinically suspected to be suffering from fungus infection. microbiological confirmation of diagnosis was obtained in 209 cases including 82 cases with mixed infections (both fungus and bacteria). the commonest species of fungus isolated was aspergillus (aspergillus niger, 67%; aspergillus fumigatus, 24%). best results in fungus infection of the ear was obtained by daily packing of the external meatus by a wick ... | 1977 | 615577 |
| [a case of broncho-pulmonary aspergillosis developing for 24 years]. | a case of allergic broncho-pulmonary aspergillosis has been diagnosed on the basis of recurrent, transient pulmonary infiltrates, serum precipitins against aspergillus fumigatus and a dual-type reaction to intradermic testing with aspergillus antigen. despite a prolonged course (24 years), lung function tests do not show changes. | 1977 | 834993 |
| studies in chronic allergic bronchopulmonary aspergillosis. 1. clinical and physiological findings. | this report outlines the clinical and physiological features in 50 asthmatic patients with chronic allergic bronchopulmonary aspergillosis in whom the diagnosis was made from 2 to 25 years ago (mean duration 10-9 years). from a questionnaire and analysis of the peak expiratory flow rate measurements it was found that they were worse in the winter months, corresponding to the maximal concentrations of aspergillus fumigatus in the atmosphere. nineteen patients reported daily sputum production of u ... | 1977 | 882939 |
| immunologic responses to therapy in allergic bronchopulmonary aspergillosis: serum ige value as an indicator and predictor of disease activity. | two patients, a child and an adult, with allergic bronchopulmonary aspergillosis were studied over an 18-month period. initially elevated total serum ige levels fell during prednisone therapy and rose prior to and during an exacerbation. total serum igg fell with therapy, whereas the values of iga and igm remained constant. specific igg and ige values against aspergillus fumigatus as measured by radioimmunoassay were elevated in both patients. specific ige values increased in each patient prior ... | 1977 | 925820 |
| central nervous system aspergillosis in two young adults. | unusual and unique features were present in the cases of two patients with central nervous system aspergillosis: one had a previously unreported complication of aspergillosis, extracranial internal carotid artery thrombosis documented by angiography, and in the other patient, cerebral granulomas developed from aspergillus fumigatus in association with intravenous narcotic abuse. the latter etiologic mechanism was suggested once before. neither of these patients showed other underlying disease. a ... | 1976 | 944399 |
| factors which influence late cutaneous allergic responses. | increased doses of ragweed antigen e, grass pollen extract, and the igg of sheep antiserum to human ige (anti-ige) were injected in intracutaneous tests in humans. with increasing doses of reactants, in individual subjects, there were the expected increases in the sizes of early wheal-and-flare responses; moreover, there was an associated increase in the magnitude and the frequency of late cutaneous allergic responses (lcar). lcar were shown to be a usual sequel to allergic reactions of sufficie ... | 1976 | 947978 |
| a study of fungal spore poupulations in the atmosphere of kuwait. | the fungal air-spora of kuwait was investigated using the petri-dish trapping technique. during the period from 1st april, 1974 to 30th june, 1975, a total of 3685 colonies were recorded from 2% malt agar plates. fifty-five genera and 116 species were identifed. alternaria occupied the first place in the order of percentage incidence. being represented by 18.3% of the entire catch, followed by aspergillus (17.1%), penicillium (14%), cladosporium (13.6%), drechslera (13.3%), and ulocladium (7.1%) ... | 1976 | 987536 |
| [aspergillus serum precipitins in patients of a lung clinic]. | the incidence and distribution of aspergillosis among patients of a lung clinic in west berlin were recorded. the immunodiffusion test (idt) was used on sera of 228 patients seen during one day to test for precipitins against a. fumigatus, a. flavus, and a. niger. precipitating antibodies specific against a. fumigatus were found in five patients, in two of them a. fumigatus was isolated simultaneously from sputum. in order to obtain a clear view of the clinical occurrence of asperigillosis and i ... | 1976 | 821738 |
| an aspergillus immunodiffusion test in the early diagnosis of aspergillosis in adult leukemia patients. | an aspergillus fumigatus immunodiffusion test was performed biweekly for one year on 80 hospitalized patients with acute leukemia to determine if serologic conversion accompanied clinical aspergillosis. a micro-ouchterlony technique with agarose was used. the antigens were prepared from concentrated a. fumigatus culture filtrates and the sera were concentrated 3-fold before testing. of 80 patients, 10 were proved at autopsy, lung biopsy, or closed space culture to have invasive aspergillosis. si ... | 1976 | 816237 |
| diagnosis and management of orbital aspergillosis. | 1976 | 1108734 | |
| cell-mediated immunity in patients with cystic fibrosis. | leucocytes from 26 patients with cystic fibrosis (cf) and 18 healthy controls were investigated by migration inhibition induced by a variety of antigens. in patients with cf cell-mediated immunity was found to human lung and pancreatic tissue extracts as well as to aspergillus fumigatus, pseudomonas aeruginosa, and food antigens but not to brain, heart, or kidney. those patients with the severest form of the disease had the greatest impairment of cell-mediated immunity, but this impairment could ... | 1976 | 813805 |
| mechanisms of activation of complement by extracts of aspergillus fumigatus. | 1976 | 819193 | |
| detection of antibodies to aspergillus fumigatus in ager gel with different antigens and immunodiffusion patterns. | 1976 | 819444 | |
| a comparison of aspergillus fumigatus antigens by counterimmunoelectrophoresis. | counterimmunoelectrophoresis (cie) has been evaluated for routine diagnostic work, using antigens prepared from 2 different isolates of aspergillus fumigatus, at 2 different concentrations. additional antigens prepared in a variety of ways and 2 commercially available antigens (bencard, london; institut pasteur, paris, france) have been compared with the routine antigens. it has been shown that the use of the routine antigens will detect the majority of positive reactions. at optimal reacting co ... | 1976 | 819832 |
| antimicrobial susceptibility testing of six clinical isolates of aspergillus. | several different methods of performing susceptibility tests on six clinical isolates of aspergillus are described. some of the conditions that affected the level of susceptibility to drugs were: the type of media used, temperature and time of incubation, and the initial inoculum size. for amphotericin b susceptibility testing, the effectiveness of the polyene antibiotic as measured by visual growth was equivalent to the effectiveness as measured by inhibition of ribonucleic acid synthesis and d ... | 1976 | 820246 |
| activity of amphotericin b, 5-fluorocytosine, and rifampin against six clinical isolates of aspergillus. | amphotericin b in combination with 5-fluorocytosine was synergistic against three clinical isolates of aspergillus fumigatus and one of three clinical isolates of a. flavus. amphotericin b in combination with rifampin was synergistic against all six clinical isolates of aspergillus tested. the levels of 5-fluorocytosine and rifampin required for synergism were higher than clinically achievable concentrations when measurements of synergism were based on visual turbidity; but when the effects of t ... | 1976 | 820247 |
| allergic bronchopulmonary aspergillosis: a study of 46 cases with special reference to laboratory aspects. | a study of 46 cases of allergic bronchopulmonary aspergillosis has been presented with special reference to laboratory aspects. episodic airways obstruction and dual skin reaction to aspergillin were present in all the cases. furthermore, there were pulmonary infiltrations in 91.1%, blood eosinophilia in 80.4%, precipitins in 91.3%, and sputum cultures repeatedly positive for a. fumigatus in 82.6% of the patients. it was observed that the multiplicity of precipitin bands corresponded to the high ... | 1976 | 821142 |
| the pathogenesis of experimental pulmonary aspergillosis in normal and cortisone-treated rats. | normal outbred adult wistar rats were resistant to infection with intratracheally administered viable spores of aspergillus fumigatus although although they developed a subacute interestitial pneumonia. while the lesions were more severe in animals immune suppressed with azathioprine (immuran) there was no evidence of hyphal growth in the pulmonary tissue. significant histological involvement was found only in those animals receiving repeared subcutaneous injections of cortisone and multiple int ... | 1976 | 1255306 |
| infection and mortality in captive wild-trapped canvasback ducks. | fungal, bacterial and malarial infections, as well as malnutrition caused heavy mortality in a group of wild-trapped canvasbacks (aythya valisineria) held in 10 x 3 x 2 m open-water pens. deaths occurred between 21 and 158 days after confinement and were associated with infections of aspergillus fumigatus, escherichia coli, staphylococcus sp., streptococcus sp., klebsiella sp., enterobacter sp., and plasmodium sp. infection and mortality was believed to result from reduced resistance associated ... | 1976 | 1255909 |
| intravitreal effects of pimaricin in experimental fungal endophthalmitis. | evaluation of 25, 50, and 100 mug of pimaricin given intravitreally to albino rabbits with aspergillus endophthalmitis revealed that 25 mug of pimaricin, while nontoxic to the retina, was ineffective in inhibiting the fungal process. a dose of 50 mug was significantly more effective in inhibiting fungal disease but also caused significant retinal damage with loss of retinal function and iridoplegia. dosages above this level resulted in vitreous retraction and degeneration, iridoplegia, and retin ... | 1976 | 766638 |
| immunologic monitoring and aspergillosis in renal transplant patients. | three cases of pulmonary aspergillosis in a "high risk" population of renal transplant recipients are presented. the source of infection was traced to the forced air exhaust system of the transplantation unit. early definitive diagnosis of the infection was very important for effective management. immunologic monitoring was demonstrated to be instrumental in indicating the early presence of infection, and as a guideline to reduced immunosuppression during therapy. bronchoscopy with brushings and ... | 1976 | 766657 |
| hatchery problems--a field report. | a long term investigational, advisory and monitoring exercise with a major hatchery emphasised the multi-disciplinary approach adopted by the agricultural development and advisory service (adas) to raise the performance of the many aspects of chick production. these included an investigation of egg handling techniques from nest box to hatcher; the adoption by the hatchery of plastic setter trays; an improvement to incubator environment; an improvement in the overall hatchery hygiene programme an ... | 1976 | 769299 |
| [experimental abortions in mice and guinea pigs caused by aspergillus fumigatus spores]. | experiments were carried out with a total of 82 laboratory animals including 56 mice and 26 guinea pigs. the possibility was tested to provoke abortions in them with the use of aspergillus fumigatus spores introduced through the trachea, orally or vaginally. the mould was isolated on chapek agar from an aborted bovine fetus. it was found that all three routes of infection lead to abortions setting in after three to five treatments on the 1st to 3rd day following the last introduction of spores. ... | 1976 | 769306 |
| mechanism of uptake of strontium isotopes in aspergillus lesions. | observations on experimental aspergillosis of chorioallantoic membranes confirmed that strontium-85 uptake in aspergillus lesions was directly due to infection by the fungus. such uptake was not found in normal or in toxoplasma gondii-infected control membranes. further, the avidity of radionuclide uptake was proportional to the mycelial mass, as previously observed clinically. investigations on 85sr containing malt extract broth aspergillus fumigatus cultures revealed that fungal hyphas did not ... | 1976 | 769615 |
| conditional virulence of a p-aminobenzoic acid-requiring mutant of aspergillus fumigatus. | the induced auxotrophy for p-aminobenzoic acid (paba) resulted in a complete loss of virulence of aspergillus fumigatus for normal as well as cortisone-treated mice. the paba-requiring mutant of a. fumigatus survived in vivo for 4 to 7 days without causing any infection. however, it showed conditional virulence in animals receiving paba in very small quantities. repeated inoculations of the viable spores of the avirulent mutant strain gave favorable results in building immunity against intraveno ... | 1976 | 770331 |
| morphogenesis and pathogenesis of chronic lung diseases. viii. cellularization of lung interlobular areas as a preliminary phase of peribronchovascular fibrosis. | an experimental investigation of the lung interlobular areas was performed by elicitation of rabbits with antigens (aspergillar and human-serum proteins) administered in aerosols or intramuscularly in freund's adjuvant. the cell accumulations in the interlobular areas developed irrespective of the antigen, duration of exposure and route of administration. the cells accumulated (reticulo-lymphoid, plasma cells, eosinocytes) were counted and the areal surface measured. the total cell count and the ... | 1976 | 772786 |
| the relative susceptibility of new zealand black and cba mice to infection with opportunistic fungal pathogens. | the susceptibility of ageing new zealand black (nzb) mice to infection with a number of opportunistic fungi and yeasts wsd compared with that of similarly aged mice of the cba strain. the nzb mice showed a greater susceptibility to lethal infection with aspergillus fumigatus, candida albicans and cryptococcus neoformans than did those of the cba strain. both mouse strains showed similar susceptibility to lethal infection by allescheria boydii, absidia corymbifera, mucor pusillus and rhizopus ory ... | 1976 | 772839 |
| pleural aspergillosis: a case report. | the first case of pleural aspergillosis on either american continent since 1958 is reported. the recent literature is reviewed. the pleura is infected by aspergillus through bronchopleural or pleurocutaneous communication. surgical removal of aspergillus infected pleura is the cornerstone of therapy. | 1976 | 773232 |
| effect of cetylpyridinium chloride on pathogenic fungi and nocardia asteroides in sputum. | the effect of cetylpyridinium chloride (cpc) on pathogenic fungi and nocardia asteroides was studied. sputa seeded with each of 11 organisms (aspergillus flavus; aspergillus fumigatus, blastomyces dermatitidis, candida albicans, coccidioides immitis, cryptococcus neoformans, geotrichum candidum, histoplasma capsulatum; nocardia asteroides, paracoccidioides brasiliensis, and sporothrix schenckii) were treated with cpc and kept for 2, 5 and 9 days. the cpc reagent used (0.5% cpc and 0.5% sodium ch ... | 1976 | 773957 |
| mycotic aneurysm of the thoracic aorta caused by aspergillus fumigatus. | a 54-year-old diabetic patient had unexplained fever and embolic occlusion of the splenic, right renal, right hypogastric, right superficial femoral, and left popliteal arteries. aspergillus fumigatus was recovered from a femoral clot. an aortogram revealed a mycotic aneurysm of the thoracic aorta to be the source of the infected emboli. surgical excision of the aneurysm and therapy with amphotericin b were unsuccessful. | 1976 | 776547 |
| acquired immunity to aspergillus fumigatus. | in mice preinfected with aspergillus fumigatus for greater than or equal to days, administration of cortisone failed to stimulate mycelial growth. the liver and heart of mice preinfected for 14 days resisted infection after a cortisone + conidia challenge. | 1976 | 776836 |
| bronchopulmonary aspergillosis. an epidemiological study in a hospital population. | in order to determine the incidence of bronchopulmonary aspergillosis in patients with other types of pulmonary pathology, 586 in-patients, out-patients and controls were examined during the period 1968-1970 in baguley hospital, manchester, england. it was found that from the 344 in-patients and out-patients with other pulmonary pathology, 6 had a definite diagnosis of allergic aspergillosis. 1 had pulmonary aspergilloma while 53 other patients demonstrated some evidence of bronchopulmonary aspe ... | 1976 | 778964 |
| cystine aminopeptidase (oxytocinase) activity in plasma and tissues of normal and infected pregnant cattle. | cystine aminopeptidase (cap) activity in tissues and in plasma from pregnant cows was measured at various stages of gestation by using the substrate s-benzyl-l-cysteine-4-nitroanilide. the cap activity was as high or higher in hepatic and renal tissues as in cotyledonary tissue. plasma cap activity was low and did not change with length of gestation, nor did it change when placentation was disrupted by infection with aspergillus fumigatus. | 1976 | 779545 |
| [pathomorphology of pulmonary aspergillosis in tuberculosis patients based on according to resection material]. | to investigate various manifestations of broncho-pulmonary aspergillosis and to ascertain its association with a previous disease there were carried out histotopographic, histological and mycological studies of specimens of the lung tissue resected in 37 patients in connection with aspergillomas of the lungs and broncho-pulmonary aspergillosis. the investigations showed that aspergillosis was one of the forms of dysbacteriosis in the human organism and could develop against the background of pos ... | 1976 | 779726 |
| sources and incidence of airborne aspergillus fumigatus (fres). | specific surveys of the air for aspergillus fumigatus were carried out in rural and urban situations over a 2-year period. overall, low concentrations of spores were recorded with a higher incidence during the "winter" months. counts in the open air and in a hospital ward showed similar fluctuations, the indoor counts being consistently lower. plant debris in the form of compost heaps and stacks of hay and straw baled with a high moisture content in which self-heating occurs, produces large numb ... | 1976 | 780000 |
| [effect of different ratios and concentrations of carbon and nitrogen in the medium on the growth and toxin formation of aspergillus fumigatus fres]. | 1976 | 781478 | |
| treatment of fungal sinusitis with autogenous vaccine. (a case report). | 1976 | 782005 | |
| [fluorescence immunologic studies of aspergillus fumigatus antibodies]. | 1976 | 782944 | |
| unusual mycotic findings in cytodiagnosis. | 1976 | 785916 | |
| ige antibodies in bronchopulmonary aspergillosis. | total serum ige and serum ige antibodies to a. fumigatus were quantitated in 143 patients with different forms of bronchopulmonary aspergillosis. total serum ige levels were elevated in all patients with allergic bronchopulmonary aspergillosis but also in some other forms of bronchopulmonary aspergillosis, thus limiting the diagnostic value of total serum ige determination in this type of pulmonary mycotic infection. specific ige antibodies to a. fumigatus could be demonstrated in all patients w ... | 1976 | 786083 |
| intraocular effects of pimaricin. | pigmented rabbits weighing 3 to 6 lbs were given bilateral intraocular injections of 250 to 1,000 mug pimaricin. following their injection, blood, aqueous and vitreous levels were determined at various time intervals during the first 24 hours and at 24 hour intervals thereafter for one week. in subsequent studies, pigmented rabbits were given bilateral intraocular injections of 5,000 spores of a. fumigatus and 30 hours later received intraocular injections of 250 to 1,000 mug pimaricin. these st ... | 1976 | 786132 |
| depletion of complement in vivo and in vitro by extracts of aspergillus fumigatus. | a new, nontoxic material extracted from aspergillus fumigatus, is described with complement-depletion capacity both in vivo and in vitro. extracts of the mycelium of a. fumigatus were found to haemolyse sheep red blood cells, to be lethal for mice and to convert c3 into its faster electrophoretic form when incubated with normal human serum. conversion did not take place when purified c3 was used, suggesting that serum factors were required in the reaction. adsorption of the extracts with activat ... | 1976 | 786901 |
| an appraisal of impregon as a deterrent of domestic fungus growth. | impregon brand of tetrachlorsalicylanilide (tcsa) has been profferred widely as a household fungistatic agent, although its value remains unproved. to assess its effects, this agent was used as a laundry and paint additive and as a treatment for burlap rug backing; after recommended applications of impregon, coded replicate materials were inoculated with mixed suspensions of fungus particles. no difference was evident in fungus growth points on fabric swatches washed in tap water with and withou ... | 1976 | 787049 |
| aspergillus prosthetic valve endocarditis. | the clinical, laboratory, and histopathological features of seven cases of aspergillus fumigatus prosthetic valve endocarditis are presented. the exact nature of the lesion, a combination of infective fungal endocarditis and thrombosis on the prosthetic valve, is discussed and the difficulties in clinical diagnosis are emphasized. helpful indications were sudden unexplained heart failure with the appearance of new murmurs, and emboli to large or medium-sized systemic arteries. fever and anaemia ... | 1976 | 788218 |
| incidence of serum antibodies to several aspergillus species and to candida albicans in cystic fibrosis. | the incidence of serum ige antibodies to several species of aspergillus and the incidence of serum precipitins to these species and to candida albicans were determined in 22 children with cystic fibrosis, 17 children with bronchial asthma, and 18 control subjects. ige antibodies were found in 50 per cent of the patients with cystic fibrosis and in 29 per cent of the patients with bronchial asthma; none was found in the control subjects. precipitins to aspergillus species were present in 59 per c ... | 1976 | 788564 |
| rast using crude and purified anti-ige. | the sensitivity of the rast using anti-ige in 125i-labelled igg fractions of sheep antiserum was compared to that using anti-ige purified by immunosorbent techniques in tests with three allergens (grass pollens, aspergillus fumigatus and the detergent enzyme "alcalase") on sera from 248 workers in a detergent factory. both anti-ige reagents measure the same antibody but the rast procedure using the crude anti-ige reagent is less sensitive than that using the immunosorbent-purified anti-ige in it ... | 1976 | 788951 |
| combination amphotericin b-rifampin therapy for pulmonary aspergillosis in a leukemic patient. | pulmonary aspergillosis developed in a 62-year-old man with acute myelogenous leukemia. therapy with amphotericin b and 5-fluorocytosine was begun. synergy between amphotericin b and rifampin was demonstrated in vitro, and therapy with firampin replaced 5-fluorocytosine. progressive clearing of the pulmonary lesion ensued, suggesting in vivo efficacy as well. further studies of patients utilizing this regimen are warranted. | 1976 | 789031 |
| salmonella and aspergillus infections in common loons overwintering in florida. | during a 5-year period (1970-1975), 190 common loons (gavia immer) from overwintering populations on the east and west coasts of florida were examined for evidence of infectious diseases. salmonella spp (representing 8 serotypes) were isolated from 27 (14%) of the loons, and lesions typical of those produced by aspergillus fumigatus were found in 34 (18%) of the loons. seven loons were infected with salmonella spp and had lesions typical of aspergillus infection. the largest number of loons (124 ... | 1976 | 789314 |
| bilateral pulmonary aspergilloma in ankylosing spondylitis treated with transthoracic intracavitary instillations of antifungal agents. | repeated transthoracic intracavitary injections of amphotericin b, nystatin and pimaricine proved a simple and safe method in the treatment of bilateral pulmonary aspergillomas in a patient with large cavities caused by lung disease in ankylosing spondylitis. both large mycetomas were dissolved by this treatment in combination with peroral corticosteroid medication, and the patient's general condition improved markedly. | 1976 | 790560 |
| direct fungal infection of the eye and its prevention. | 1976 | 791354 | |
| mycotic keratitis in nigeria. a study of 21 cases. | a clinical and mycological study of 21 cases of mycotic keratitis, a clinical entity not yet reported from nigeria or west africa, showed that fusarium solani was the predominant aetiological agent. it was isolated from 12 cases. four of the remaining nine cases were caused by aspergillus fumigatus, one by a. flavus, two by penicillium citrinum, and one each by p. expansum and penicillium sp. all the 12 isolates of f. solani grew well at 37 degrees c and survived at 40 degrees c. two cases, one ... | 1976 | 791355 |
| isolation of actinomycetes and fungi from mouldy hay using a sedimentation chamber. | 1976 | 791914 | |
| hemoptysis with cavitary lung lesion. | 1976 | 792492 | |
| [dependence of the growth and toxin formation of aspergillus fumigatus fres.on the cultivation temperature]. | 1976 | 792639 | |
| [comparative enzymatic study of two strains of aspergillus fumigatus and of a. fischeri of sapropytic origin or isolated from human or animal lesions: practical diagnostic applications]. | 14 enzymatic activities (3 dehydrogenases and 11 hydrolases) were systematically investigated in the extracts of 2 strains of aspergillus fischeri and 14 strains of a. fumigatus (8 isolated from human or animal lesions named 'pathogenic' strains and 6 strains of saprophytic origin). the enzymic composition of a. fumigatus appeared to be very different from one strain to another but no relationships could be established between enzymic differences and origin of the strains. in addition, the immun ... | 1976 | 792691 |
| [immuno-enzymatic technic (e.l.i.s.a.) applied to the serological diagnosis of human candidiasis and aspergillosis. preliminary results]. | 1976 | 792812 | |
| [pleural aspergillosis in clinical records in the years 1965-1974]. | 1976 | 792829 | |
| [removal of pulmonary aspergilloma by aspiration drainage]. | 1976 | 794564 | |
| [the effect of clotrimazole (canesten) on the ultrastructure of molds (aspergillus fumigatus) in the infected animal]. | 1976 | 794709 | |
| [mucoid impaction of the bronchi (author's transl)]. | 1976 | 794963 | |
| extrinsic allergic alveolitis after aspergillus fumigatus inhalation. evidence of a type iv immunologic pathogenesis. | three weeks after a massive inhalation of mold present on infected oats, a farmer's wife had extrinsic allergic alveolitis. aspergillus fumigatus was cultured from the moldy oats and from deep bronchial washings obtained at fiberoptic bronchoscopy. spores and hyphae characteristic of aspergillus species were demonstrated within granulomas in the pulmonary tissue obtained by transbrochial biopsy. serum precipitins, delayed (48 hour) cutaneous hypersensitivity and in vitro lymphocyte transformatio ... | 1976 | 795300 |
| radioallergosorbent test (rast) studies with insolubilized polysaccharides. | polysaccharide preparations from aspergillus fumigatus and candida albicans when used with some human sera were found to fix complement and precipitate with specific antibodies present in the sera. precipitins consisted predominantly of igg with traces of igm and iga. following insolubilization of the fungal polysaccharide preparations with the n-carboxyanhydride of l-leucine, reactivity with serum precipitins was retained and reaction with ige antibodies was demonstrated using the radioallergos ... | 1976 | 795563 |
| [the possibility of an etiopathogenetic role of the fungi isolated from the respiratory tract (author's transl)]. | the large number of fungous strains isolated from specimens coming from the respiratory tract is a possible source of diagnostic failures. for an accurate diagnosis it is necessary to screen between fungi in a saprophitic and in a parasitic position. this is very difficult both for fungi, which are largely spread in the environment, like aspergillus sp., and for fungi, which are commonly found on the mucous membranes, like candida or torulopsis sp. the actual pathogenetic activity of a fungous s ... | 1976 | 797323 |
| [an antigenic extract analyzed by bidimensional immunoelectrophoresis (author's transl)]. | an antigenic extract from broth culture of aspergillus fumigatus has been analyzed by bidimensional immunoelectrophoresis of clark and freeman against rabbit antiserum. the analysis has show the extract to be constituted by seven different antigens. | 1976 | 797324 |
| roentgenographic recognition of bronchoceles. | bronchoceles often have characteristic plain film, tomographic, and bronchographic appearances, and they may trap air. roentgenographic recognition of bronchoceles can allow them to be distinguished from neoplasms and sometimes help avoid unnecessary surgery. | 1976 | 798296 |
| [stages of development of aspergillus-mycetom and their roentgenographic signs (author's transl)]. | a series of 13 cases of aspergillus-infection in the respiratory tract are reviewed. a case of rapid development of an intrapleural aspergillus-mycetom is presented. a complete series of chest roentgenograms and operation-photos allowed to demonstrate like with a quick-motion apparatus 3 stages of development of an intrapleural aspergillus-myceton: i. infection through aspergilli of a residual intrapleural cavity by the bronchial way. pleural thickening as reaction to the irritation. ii. develop ... | 1976 | 799407 |
| [properties of the contagious ecthyma virus used for vaccine production]. | experiments were carried out to establish the effect of some antibiotics and merthiolate on the vaccinal phylaxia strain of ecthyma contagiosa. besides, followed up was the effect of these antibiotics on concomitant microflora that had multipled in the virus suspension. trials were also made to titrate the vaccinal strain on lambs through scarification. titration was carried out by the method of schmidt. virus dilutions of 10-1 were applied following scarification on the the thighs and fore limb ... | 1976 | 799865 |
| mycotoxicoses. | 1976 | 15366 | |
| serological investigations in 15 cases of bird fanciers disease. | serological studies in 15 patients with bird fanciers disease are reported. quantitative analysis of serum proteins showed elevation of igg in almost every case. high ige was observed in three patients with isolated asthmatic reactions. in four patients alpha1-antitrypsin was transiently diminished. two of these had heterozygous deficiency of this protein (genotype ms and mz). precipitins against avian sera and avian droppings were found in all patients, but also in some exposed and nonexposed c ... | 1976 | 55391 |
| serum concentration of specific ige antibody against aspergillus fumigatus and identification of the fungal allergen. | 1976 | 58749 | |
| lymphocyte sensitization to aspergillus fumigatus antigens in pulmonary diseases in man. | in vitro studies of t-lymphocyte responses using five different batches of aspergillus fumigatus antigens, were undertaken in twelve patients with a. fumigatus related lung disease and in three normal controls. using a leucocyte migration method, five of the twelve patients showed significant inhibition of leucocyte migration with a migration index of 0-80 or less to a. fumigatus, but in only three was this demonstrated with more than one batch of antigen (one patient with aspergilloma and two w ... | 1976 | 59639 |
| positive controls for fungal detection in tissue sections. | lyophilized histoplasma capsulatum, coccidioides immitis, blastomyces dermatitidis and aspergillus fumigatus are rehydrated, evenly dispersed, and made into smears using a bacteriological loop and alcohol-cleaned slides. smears are air dried for 15 minutes, fixed in concentrated formaldehyde fumes for 30 minutes, postfixed for one hour in ten per cent buffered formaldehyde, and stored at room temperature. these preparations are used as positive controls for the grocott stain as recommended for c ... | 1976 | 60881 |
| cytophilic antibodies in bronchopulmonary aspergilloma and cryptogenic pulmonary eosinophilia. | the immunoglobulin class and subclass of cytophilic antibodies have been studied using peripheral leucocytes from twenty-two patients with allergic bronchopulmonary aspergillosis, aspergilloma and cryptogenic pulmonary eosinophilia. in patients with allergic bronchopulmonary aspergillosis, significantly increased histamine liberation occurred following challenge of their leucocytes with antisera to ige, igg2, igg3 and igg4 as well as with aspergillus fumigatus antigen. the results were considera ... | 1976 | 63346 |
| high-temperature production of protein-enriched feed from cassava by fungi. | a simple, nonaseptic, low-cast process for the conversion of cassava, a starchy tropical root crop, into microbial protein for use as animal feed was sought. screening tests culminated in the isolation of a thermotolerant, amylase-producing mold, designated i-21, which was identified as aspergillus fumigatus. the optimum ph for protein synthesis was 3-5, but the optimum temperature was less than the desired temperature (larger than or equal to 45 c) required for a nonaseptic fermentation. a. fum ... | 1975 | 2105 |
| primary interaction between antibody and components of alternaria. i. immunology and chemical characteristics of labeled antigens. | components were isolated from alternaria tenuis and its culture filtrate, and were radiolabeled with 123-i. the labeled antigenic components had a high polysaccharide content as determined by staining patterns following electrophoresis in polyacrylamide gels and by inactivation with sodium metaperiodate. a primary binding test was employed to detect and measure serum antibodies to the components from a. tennuis. this procedure was more sensitive in detecting antibodies that bound to antigens tha ... | 1975 | 48526 |
| glycoprotein enzymes secreted by aspergillus fumigatus: purification and properties of a second beta-glucosidase. | a second extracellular beta-glucosidase (betalarge) of aspergillus fumigatus was purified to homogeneity and shown to be a glycoprotein, as determined by polyacrylamide gel electrophoresis followed by staining for protein and for carbohydrate. its molecular weight was approximately 340,000 by gel filtration, while sodium dodecyl sulfate-polyacrylamide gel electrophoresis gave an apparent molecular weight of 170,000, suggesting that the enzyme has two subunits. the glucosidase contained covalentl ... | 1975 | 51848 |