Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| colonization by salmonella typhimurium and shigella flexneri iii of the gastrointestinal tract of mice treated with beta-2-thienylalanine and streptomycin. | mice fed beta-2-thienylalanine (beta-2-t) by oesophageal tube were no more susceptible to gastrointestinal tract colonization by salmonella typhimurium or shigella flexneri iii than control mice fed water. in both beta-2-t-fed and water-fed groups, the increasing dosage of s. typhimurium, in logarithmic increments to groups of mice, resulted in increasing numbers of these bacteria detectable on dilution plates from organ homogenates. colonization by s. flexneri iii only occurred at a dosage of 1 ... | 1979 | 399720 |
| [research methods of r factors (author's transl)]. | after having outlined the routine methods for the study of drug resistance plasmids used at highly specialized centres such as the london enteric reference laboratory, the aa. examine the most practical methods of a pure and simple way of discovering r factors in enterobacteria. a brief reference is made to some of the in vivo transfer techniques before reducing the various possibilities of in vitro survey to essentials. the experimental conditions realized by some aa. for mating in liquid media ... | 1979 | 400251 |
| [drug resistance of shigella strains isolated in central italy during 1969-1976 (author's transl)]. | only ninety-three strains of shigella, eightyseven of which have been identified as s. sonnei and six as s. flexneri were collected during 1969-1976 at the pathogen enterobacteria centre of pisa in central italy, as evidence of an epidemiological situation marked by a rare occurrence of syndromes related to these organisms. the collected strains were tested with disks of nine antibacterial drugs in common use: the survey detected sensitivity of all the strains to cephaloridine, ampicillin, carbe ... | 1979 | 400254 |
| resistance to lyophilization of salmonella typhi, escherichia coli and shigella flexneri strains. | 1979 | 400513 | |
| shigellae and reiter's syndrome. | 1979 | 400766 | |
| [role of histamine in the development of inflammation of the large intestine mucosa in acute dysentery]. | 1979 | 370753 | |
| phenylalanyl-trna synthetase induced conformational change of escherichia coli trna phe. | 1979 | 383142 | |
| salmonella phage glycanases: substrate specificity of the phage p22 endo-rhamnosidase. | interaction between phage p22 and phenol-water extracted lipopolysaccharides from sensitive salmonella bacteria belonging to serogroups a, b and di results in hydrolysis of the alpha-l-rhamnosyl linkages within the tetrasaccharide repeating unit of the o-antigenic polysaccharide chain. these o-antigens have identical structures except for the nature of the 3,6-dideoxy-hexosyl group linked to o-3 of the d-mannosyl residue. removal of the dideoxysugar, or periodate oxidation followed by borohydrid ... | 1979 | 383902 |
| [humoral factor study of natural immunity in sonne and flexner dysenteries]. | 1979 | 386651 | |
| [seasonal problems of bacterial dysentery in the dagestan assr]. | during the period of 1959-1973 bacterial dysentery showed high morbidity rate in daghestan in all seasons, this tendency existing both in urban and rural areas. the peculiarity of the monthly distribution of dysentery cases, observed all over the repulic, was the shift of the morbidity peak from august to september-october, and in some years even to november; this could be clearly observed from the analysis of the material as a whole and from the analysis of dysentery morbidity rates in rural an ... | 1979 | 386661 |
| [transduction analysis of the genetic control of synthesis of the r-nucleus of the lipopolysaccharide of o-antigen]. | 1979 | 386667 | |
| hepatic microsomal metabolism of epinephrine and adrenochrome by superoxide-dependent and -independent pathways. | 1979 | 31892 | |
| pharmacokinetics of the new beta-adrenoceptor blocker sl 75212 in man after repeated oral administration [proceedings]. | 1979 | 41560 | |
| pseudomonas arthritis following puncture wounds of the foot. | 1979 | 34012 | |
| horizontal organization of velocity characteristics in area 18 of the cat [proceedings]. | 1979 | 92238 | |
| [influence of a dialyzable serum factor on the activity of beta-galactosidase from human liver (proceedings)]. | 1979 | 92267 | |
| immunologic regulation in pregnancy. | theories to explain the failure of rejection of the fetus by the mother during pregnancy include immunologic privilege of the uterus as a graft site, lack of transplantation antigen expression on the trophoblast, weakening of maternal cellular immunity during pregnancy, and separation of maternal and fetal circulations. evidence for and against each of these theories is discussed. local concentration of a variety of hormones, including human chorionic gonadotropin (hcg), sex steroids, alpha-feto ... | 1979 | 92318 |
| the relation between the concentration of placental specific proteins in retroplacental and peripheral blood. | concentrations of four placental proteins: human placental lactogen (hpl), placental protein 5 (pp5), pregnancy specific beta 1 glycoprotein (sp1) and human chorionic gonadotrophin (hcg), and a normal serum component, alpha 2 macroglobulin, were measured in the peripheral circulation and in blood obtained from the retroplacental space in 20 women at term delivery. levels of hpl and pp5 were higher in the retroplacental blood than in the peripheral circulation in all patients. by contrast, levels ... | 1979 | 92339 |
| guinea-pig alpha 1 microglobulin. isolation and properties in comparison with human alpha 1 microglobulin. | 1979 | 92407 | |
| nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry. | nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ... | 1979 | 92496 |
| immunoelectron microscopic localization of herpes simplex virus antigens in infected cells using the unlabeled antibody-enzyme method. | subcellular localization of viral antigens was demonstrated during viral morphogenesis using herpes simplex virus type 1 (hsv-1) infected monolayers of rabbit cornea cells. the localization was done by immunoelectron microscopy employing the peroxidase-antiperoxidase (pap) immunocytochemical technique and the postembedding staining method. the localization of viral antigens was followed at time intervals during infection from 2 to 19 hr. after exposure of sections to either polyspecific antibodi ... | 1979 | 92500 |
| [modified method of obtaining washings of the large intestine for determining coproantibodies and immunoglobulins in the dynamics of acute dysentery]. | the study of the washings obtained during rectoscopy from the mucous membrane of the large intestine with the use of a special attachment for a rectoscope revealed that this method had a number of advantages when compared with the study of coprofiltrates; in particular, this method allowed to obtain pure secretions of the mucous membrane free of fecal admixtures and to concentrate the gamma globulin fraction. the study of the dynamics of coproantibody secretion in acute dysentery revealed that c ... | 1979 | 92867 |
| [relations between oxoglutarate transport function and variations of space in rat heart mitochondria (proceedings)]. | 1979 | 92958 | |
| selective aromatic-hydrophobic binding and fractionation of immunoglobulin by means of phenyl-(ch2)n-nh-substituted agaroses. | 1979 | 92988 | |
| [determination of the c-reactive protein content of human whole blood]. | 1979 | 93165 | |
| human alphafetoprotein 1956-1978. | 1979 | 93405 | |
| effect of azacytidine on simian virus 40 nucleoprotein complexes. | simian virus 40 nucleoprotein complexes synthesized in the presence of 5-azacytidine showed small differences in sedimentation rate on neutral sucrose and buoyant density in metrizamide and cesium chloride. simian virus 40 deoxyribonucleic acid (dna) i, isolated from the nucleoprotein complexes of drug-treated cultures, was found to band at a higher buoyant density and therefore had a decreased ability to bind ethidium bromide. the data indicated that these molecules were deficient in superhelic ... | 1979 | 93427 |
| evidence in vitro for a participation of the arginine repressor in cumulative repression of escherichia coli carbamoylphosphate synthase [proceedings]. | 1979 | 93462 | |
| a novel class of schizosaccharomyces pombe mutants, phenotypically unable to grow on glycerol, a respiratory substrate, but still able to oxidize glycerol aerobically [proceedings]. | 1979 | 93469 | |
| effects of intrathecal and intracerebroventricular injections of substance p on nociception in the rat and mouse [proceedings]. | 1979 | 93501 | |
| surface-associated host proteins on virulent treponema pallidum. | a surface coat of host serum proteins was detected on virulent treponema pallidum by sodium dodecyl sulfate-gel electrophoresis. the loosely associated serum proteins could be removed by repeated washings in a protein-free medium. washed t. pallidum retained the ability to readsorb numerous host proteins from rabbit serum as well as iodinated rabbit or human albumin. in addition, various avidly associated host serum proteins including albumin, alpha(2)-macroglobulin, transferrin, ceruloplasmin, ... | 1979 | 93574 |
| antigenic heterogeneity of the non-serogroup antigen structure of neisseria gonorrhoeae lipopolysaccharides. | studies of the antigenic structure of the polysaccharide component of gonococcal lipopolysaccaride (lps) indicated that the non-serogroup antigen structure is antigenically heterogeneous. immunodiffusion studies of gc4 strain 8551 indicated that in addition to the gc serogroup determinent, this polysaccharide contains two other sets of determinants, one which is shared with the other five gc serogroups and a second which is shared by the gc1 and gc3 serogroups. enzyme-linked immunosorbent assay ... | 1979 | 93575 |
| abortive expression of the epstein-barr virus (ebv) cycle in a variety of ebv dna-containing cell lines, as reflected by nucleic acid hybridization in situ. | a variety of epstein-barr virus (ebv) dna-containing cell lines have been tested for the expression of the ebv-associated antigens ebna (nuclear antigen), ea (early antigen), and vca (viral capsid antigen), and for the presence of cells containing disproportionate amounts of ebv dna. the antigen tests utilized immunofluorescence and 125i-labelled antibodies combined with autoradiography. ebv-dna was detected by in situ hybridization with 3h-labelled ebv rna complementary to p3hr-1 ebv dna (p-ebv ... | 1979 | 93584 |
| characteristics and genetic control of nk-cell-mediated cytotoxicity activated by naturally acquired infection in the mouse. | most and perhaps all natural-cell-mediated cytotoxicity (ncmc) may be activated by a response to exogenous infections. specific-pathogen-free (spf) mice have little or no natural killer (nk) cell activity, but when they are relocated in conventional conditions, they develop strong ncmc within 2 to 3 days. unlike other spf animals, hypothymic nude mice display good ncmc which is further augmented upon their entry into a pathogenic environment. the ontogeny, genetic control and other features of p ... | 1979 | 93585 |
| alpha-fetoprotein inhibits antibody binding to acetylcholine receptor. significance for myasthenia gravis and other autoimmune diseases. | 1979 | 93589 | |
| 1-isoamyl-3-isobutylxanthine: a remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic amp in brain slices. | 1979 | 93674 | |
| in vivo release of substance p in the cat substantia nigra. | push-pull cannuale were implanted into the substantia nigra (sn) and the caudate nucleus (cn) of the cat to study the in vivo release of substance p (sp), using a radioimmunoassay and high pressure liquid chromatography (hplc) analysis. the spontaneous release of sp could be detected in the sn and the cn. potassium (50 mm) locally applied stimulated sp release in both structures. furthermore an important evoked release of sp was observed in the sn during depolarization of striato-nigral sp fiber ... | 1979 | 93729 |
| characterization and mode of action of a bacteriocin produced by a bacteroides fragilis strain. | a bacteroides fragilis strain produces a low-molecular-weight (13,500 to 18,700), proteinaceous bacteriocin during the stationary growth phase. the extracellular bacteriocin is not inducible by ultraviolet light or mitomycin c and is stable between ph 7.5 and 8.2. the majority of the bacteriocin is thermolabile, but a small proportion (3%) of the bacteriocin is stable after autoclaving at 121 degrees c for 15 min. killing of sensitive bacteroides cells follows single-hit kinetics, and the intera ... | 1979 | 93876 |
| effects of exogenous gonadotropic and steroid hormones on the social behaviour and gonadal maturation of male domestic ducklings anas platyrhynchos l. | male domestic ducklings were injected during their first month of life with mammalian gonadotrophins (ovine lh or fsh, hmg) or gonadal steroids (testosterone or oestradiol). lh and testosterone stimulated sexual behaviour while oestradiol inhibited the increase of aggression observed in control birds during the experiment. the mammalian gonadotrophins did not increase plasma testosterone but nevertheless they all stimulated the testis growth. several hypotheses which could explain this finding ( ... | 1979 | 93890 |
| the lac-test, a rapid method for the detection of agents inducing sos-dna repair in esch erichia coli [proceedings]. | 1979 | 93911 | |
| semicarbazide-sensitive amine oxidase in rat aorta: a plasma-membrane enzyme [proceedings]. | 1979 | 93954 | |
| a developmental model for studying choline acetyltransferase transport in chick motoneurons. | the proximodistal axonal transport of choline acetyltransferase (chac) has been studied in the chick sciatic nerve in the absence of any experimental manipulation. the phenomenon utilized by us is a physiological transient fall in the activity of chac. this fall occurs in most areas of the chick central nervous system after hatching, and moves toward the periphery along the nerves. having ruled out the presence of transient inhibitors, the movement of the fall towards skeletal muscles has been c ... | 1979 | 94010 |
| diet composition and insulin effect on amylase to lipase ratio in pancreas of diabetic rats. | in man and in rat, the diabetic state is associated with diseases of exocrine pancreatic function. in this work, streptozotocin diabetes was shown to lead to a 95% decrease in the amylase to lipase ratio in rats. diabetes was reversed by either pancreas transplantation or insulin treatment. transplantation of neonatal pancreases was successful in reversing the diabetic-induced alterations of exocrine pancreatic function. to assess whether insulin acts directly on the exocrine pancreas, or throug ... | 1979 | 94021 |
| conversion of androstenedione to estrone in human fibroblasts cultured from prostate, genital and nongenital skin. | 1979 | 94031 | |
| antigenicity of casein enzymatic hydrolysate. | an enzymatic hydrolysate of bovine casein were studied for molecular size and antigenic properties. as determined by sephadex g-25 gel filtration, polypeptide fractions having molecular weights greater than 1,000 were not detected in the soluble fraction of the casein hydrolysate. antigenicity of the fraction was not detected by heterologous passive cutaneous anaphylaxis in guinea pig-rabbit antiserum system mediated by immunoglobulin g types of antibody (guinea pig passive cutaneous anaphylaxis ... | 1979 | 94065 |
| correlation between morbidity and the level of serum antibodies and virus-neutralizing inhibitors in different influenza a/hong-kong epidemics. | 1979 | 94079 | |
| structure of the rna portion of the rna-linked dna pieces in bacteriophage t4-infected escherichia coli cells. | 1979 | 94107 | |
| [existence of r-protein antigens in group f streptococcal cells.--investigation with cells of group f streptococcal reference stain o'mahoney (colindale)]. | 1979 | 94109 | |
| antifetal and tumor-specific reactivity in human osteosarcoma. | 1979 | 94187 | |
| induction of delayed-type sensitivity to leishmania parasite in a case of leishmaniasis cutanea diffusa with bcg and cord-factor (trehalose-6-6' dimycolate). | the delayed hypersensitivity against the leishmania parasite was restored to a patient who had suffered from diffuse cutaneous leishmaniasis (dcl) for 26 years, by the application of an ointment containing heat-killed and lyophilized bcg and cord-factor (trehalose-6-6'-dimycolate) after stripping the affected and adjacent areas with scotch-tape. | 1979 | 94221 |
| cross-reactions between haemophilus influenzae and nineteen other bacterial species. | forty-one different antigens were demonstrated in an antigen preparation obtained by sonication of a haemophilus influenzae (h. influenzae) type b strain, using crossed immunoelectrophoresis and antiserum obtained from rabbits. antigens were characterized by absorption experiments with whole heat-killed bacteria, temperature resistance and protein and polysaccharide staining. cross-reactions between h. influenzae type b and 19 other bacterial species were studied by various quantitative immunoel ... | 1979 | 94235 |
| crossed immunoelectrophoretic analyses of antigens from trypanosoma lewisi and trypanosoma musculi. | 1979 | 94319 | |
| chlamydia psittaci: growth characteristics and enumeration of serotypes 1 and 2 in cultured cells. | the growth characteristics of chlamydia psittaci serotypes 1 and 2 (ovine and bovine origin) were studed in mouse l cells. formation of inclusions and yield of infectious progeny for serotype 1 were maximal when host cells were treated with cycloheximide and the ph in the cell culture medium was 7.2-7.4. the number of cells that contained inclusions and the infectivity yield for serotype 2 were maximal when the ph was 6.6-7.0. treatments with diethylaminoethyl dextran and cycloheximide increased ... | 1979 | 94339 |
| comparative studies on ls antigens induced by vaccinia and cowpox viruses. | the constituents of ls antigen from cells infected with vaccinia virus and with cowpox virus were compared by immunoprecipitation and sds-polyacrylamide gel electrophoresis (sds-page). antiserum to the ls antigen from cells infected with vaccinia virus reacted with at least five polypeptides in cells infected with either virus. four of these polypeptides were similar sizes in cells infected with the two viruses. however, one major polypeptide with a mol. wt. of about 100 000 (100 k) detected in ... | 1979 | 94351 |
| time courses of carbachol-induced responses in guinea pig atria under the influence of ouabain, calcium, and rate of stimulation. | the response of isolated left atria of guinea pigs to carbachol was measured in the presence and during washout of the drug. the time courses of the negative inotropic effect and of the rate of shortening in action potential duration were compared. the initial rapid decline in force of contraction was followed by a slowly developing partial recovery (fading). after removal of the drug, a transient phase of hypercontractility was observed before the control level was reached again. in contrast to ... | 1979 | 94392 |
| effects of subminimal inhibitory concentrations of ampicillin, chloramphenicol, and nitrofurantoin on the attachment of escherichia coli to human uroepithelial cells in vitro. | an in vitro system with epithelial cells of the human urinary tract and escherichia coli isolated from the urine of pateints with acute pyelonephritis was used for tests of the effect of antibacterial agents on bacterial adhesion. e. coli treated with subminimal inhibitory amounts of ampicillin attached less than untreated control bacteria. subminimal inhibitory amounts of chloramphenicol and nitrofurantoin had no effect on adhesion of the 15 strains of e. coli tested. the combination of bacteri ... | 1979 | 94452 |
| the rate of movement of [3h]-water and [14c]-dextran into the gingival sulcus of the rabbit. | 1979 | 94543 | |
| acute and chronic beta-receptor blockage with propranolol and the cardiovascular responses to intravenous sodium nitroprusside in the conscious rabbit. | sodium nitroprusside infused intravenously into conscious rabbits lowered blood pressure and raised heart rate and plasma noradrenaline. acute beta blockade with propranolol, 2 mg/kg/hr i.v. for 2 hr, increased resting plasma noradrenaline and did not change the hypotensive effects of nitroprusside or the rise in plasma noradrenaline but attenuated the increase in heart rate. chronic treatment with propranolol, 2 mg/kg twice daily for 3 weeks, did not modify the cardiovascular or reflex effects ... | 1979 | 94618 |
| hla types in corneal diseases. | evaluation of the results of hla typing of 187 patients grouped into herpetic keratitis (37), non-herpetic keratitis (43), keratoconus (42), endothelial dystrophy (23), stromal dystrophy (13), lues (5), and injuries (24), failed to show convincing deviations in any of the groups from a normal control series (2900 persons). yet, as for the herpes group, a rise in b5 must strongly be suspected. the data are presented and possible implications are discussed. | 1979 | 94740 |
| glucose and phosphorus utilization by two dermatophytes. | trichophyton mentagrophytes and aspergillus fumigatus dissimilated glucose through emp pathway. oxygen and inorganic phosphorus were found to control the rate and extent of glucose metabolism. | 1979 | 94752 |
| determinants of 5-phosphoribosyl-1-pyrophosphate (prpp) synthesis in human fibroblasts. | 1979 | 94761 | |
| [comparative study of 5 alpha-reductase activity in the prostate and the human scalp]. | 1979 | 94780 | |
| a research on the action of testosterone propionate and of ciproterone acetate on the mouse-killing behaviour of the adult rat. | data demonstrate exactly that testosterone favour above all the killing behaviour of castrate males at birth in comparison with control males while ciproterone acetate turns out to be more effective in diminishing the killing behaviour of males having integral testicle and of androgenized females at birth in comparison with castrated males. the results point out that the killing behaviour of rats is affected by the presence of testosterone in the first days of life, and in the grown-up animal. | 1979 | 94826 |
| chromatography of non-human albumins on cibacron blue-agarose. application to the separation of albumin from rat alpha-fetoprotein. | 1979 | 94917 | |
| staining of legionella pneumophila. | 1979 | 85128 | |
| goitrogens. | 1979 | 85506 | |
| comparison of the temperature-dependence of rapid axonal transport and microtubules in nerves of the rabbit and bullfrog. | 1. the average velocity of transport of dopamine-beta-hydroxylase, an enzyme confined to unmyelinated adrenergic nerves, was measured in rabbit and bullfrog sciatic nerves or branches incubated in vitro at various temperatures. in parallel experiments, the number and density of microtubules were measured in cross-sections of randomly selected unmyelinated axons from another set of nerves incubated under the same conditions. 2. average transport velocity was exponentially related to temperature o ... | 1979 | 85705 |
| definition of two ld antigens in rhesus monkeys. | two rhesus (macaca mulatta) monkey lymphocyte-defined (ld) antigens have been identified using two typing cells as stiumlators in a one-way mixed leukocyte culture (mlc) assay. an analysis of the genetic behavior of these ld antigens in six rhesus monkey families revealed that both antigens were linked with rhla. one probable recombinant indicated that the ld locus lies outside the two known rhla-sd loci and the locus which controls the serum protein, properdin b(bf). these two antigens, ld1 and ... | 1979 | 87026 |
| similarity of casein- and endotoxin-induced, myeloma- associated and aged sjl/j amyloid in various strains of mice. | amyloidosis was induced in a number of strains of mice by repeated injections of casein and endotoxin. spontaneous amyloid was obtained from balb/c mice bearing a myeloma tumor (igg2a producing mopc 173 tumor) and from aged sjl/j mice. both the induced and spontaneous forms were similar in their size, immunological reactivity, peptide maps and in the susceptibility of histological sections to oxidizing agents with or without trypsin digestion. since case-induced murine amyloid resembles the noni ... | 1979 | 87374 |
| moloney virus-induced cell surface antigens and histocompatibility antigens are located on distinct molecules. | 1979 | 87439 | |
| some progress with nasopharyngeal carcinoma. | 1979 | 87621 | |
| autonomic block, cardiovascular depression and histamine release produced by polymyxin b in the cat. | the present study quantifies the autonomic block, the cardiovascular depression and the histamine releasing effects of polymyxin b in nine anaesthetized cats. the dose requirements for 50 per cent depression of the mean arterial blood pressure, the bradycardiac response to vagal stimulation, and the contraction of the nictitating membrane elicited by pre-ganglionic and post-ganglionic stimulation of the cervical sympathetic trunk have a narrow range of scatter, being of the order of 6--12 mg.kg- ... | 1979 | 89005 |
| reaction of cells from early chick embryos with antiserum against mouse sperm cells. | 1979 | 89009 | |
| nonspecific suppressor cell activity and specific cellular unresponsiveness in rat schistosomiasis. | 1979 | 89037 | |
| immunological unresponsiveness in mice. ii. cellular basis of immunological unresponsiveness induced in foetal and neonatal mice by transfer of human gamma-globulin by the maternal route. | the cellular basis of the mechanism of immunological tolerance to human gamma-globulin (h gamma g) induced in foetal and neonatal mice by materno-foetal or materno-neonatal transfer after a single injection of tolerogen (deaggregated h gamma g) into the mothers was investigated using a cell transfer system and assays of passive haemagglutinating antibodies and plaque-forming cells to h gamma g. the results demonstrated that b cells are mainly involved in the tolerance induced on the fourteenth d ... | 1979 | 89080 |
| preliminary studies on nasal decongestant activity from the seed of the shea butter tree, butyrospermum parkii. | 1 the seed of butyrospermum parkii yields shea butter which according to local traditional healers relieves inflammation of the nostrils. 2 since there is as yet no absolutely satisfactory nasal decongestant in clinical use, it was decided to investigate the effects of shea butter in nasal congestion. the substance was prepared in the laboratory. 3 the human subjects used were those suffering from rhinitis with moderate to severe nasal congestion. they were divided into the test group which rece ... | 1979 | 89854 |
| the cellular basis of transplantation tolerance in the rat. | 1979 | 90010 | |
| immunofluorescent staining of platelet suspensions and detection of antiplatelet antibody in patients with idiopathic thrombocytopenic purpura. | direct immunofluorescent staining of 31 specimens of platelets obtained from 13 cases of idiopathic thrombocytopenic purpura (itp) revealed positive staining on the surface of platelets for both immunoglobulins (igs) and human b1c globulin in 9 specimens, for only igs in 1 specimen and for human b1c alone in 5 specimens. the pattern of the positive immunofluorescent staining was granular. indirect immunofluorescent staining of normal platelets in serum obtained from patients with itp was positiv ... | 1979 | 88810 |
| differentiation between cyclic amp level and allergic histamine release in mast cells [proceedings]. | 1979 | 88891 | |
| characterization of an rna-directed dna-polymerase from a cell line derived from a radiation-induced lymphoma in mice. | an rna-directed dna polymerase was purified from a cell line derived from a radiation-induced lymphoma in nih swiss mice which produced non-infectious type c virus particles. the enzyme was isolated from a high speed particulate fraction which bands at a density of 1.16--1.19 g/ml in a sucrose gradient, and purified by successive chromatography on deae-cellulose, phosphocellulose and hydroxyapatite. the purified dna polymerase has a molecular weight of 68 000, a ph optimum of 7.5, a kcl optimum ... | 1979 | 90522 |
| complement profiles in monkeys subjected to aggregate (immune complex) anaphylaxis, and following injection of soluble and particulate polysaccharides. | complement profiles were established in four groups of macaca irus monkeys: (i) aggregate (immune complex) anaphylaxis was induced following immunization, with ovalbumin. upon challenge, systemic arterial pressure decreased from 115 to 50 mm hg (mean values) in 10 min. the complement profiles revealed decreases in: c1q to less than 10% of initial value within 5 min; c4 proportional to hypotension; c3 slowly to 60% at 24 h; c5, c6, c7, c8 and factor b to about 80% of initial value in 5--30 min. c ... | 1979 | 90656 |
| prolonged survival of corneal allografts in rabbits treated with cyclosporin a. | 1979 | 90771 | |
| maternal blocking factors in human pregnancy are found in plasma not serum. | pregnancy plasma and sera were evaluated for differential blocking effects in mixed lymphocyte culture reactions. autologous pregnancy plasma, but not serum was found to contain a specific allogeneic inhibitor for paternal lymphocytes. | 1979 | 90919 |
| [vital staining of retina and uvea with trypan blue--particularly in comparison with neutral red staining (author's transl)]. | 1979 | 91316 | |
| connectivity of the auditory forebrain nuclei in the guinea fowl (numida meleagris). | injection of tritiated leucine and proline into the nucleus ovoidalis of the guinea fowl (numida meleagris) produces terminal labeling in the palaeostriatum and in three adjacent zones (field l1-l3) of the auditory neostriatum (an). l2, situated between l1 and l3, receives the main input and corresponds to the former field l of rose. these neuroanatomically defined zones of the auditory neostriatum are also characterized by differing properties of their neurons. injection of radioactive material ... | 1979 | 91442 |
| antigen specific t cell-mediated suppression. vi. properties of in vitro generated l-glutamic acid60-l-alanine30-l-tyrosine10 (gat)-specific t-suppressor factor(s) (gat-tsf) in responder mouse strains. | 1979 | 91643 | |
| histochemical studies of mucosubstances and keratins of thymic corpuscles. | keratin and prekeratin have been visualized histochemically by testing the reactivity of disulfide groups in the thymic corpuscles of the sheep. rhesus monkey, rabbit and dog, and the reactivity of sulfhydryl groups in the sheep, rhesus monkey, rabbit and rat. ten to 50% of the thymic corpuscles showed keratinization by this method. acidic mucosubstances were visualized histochemically in the rhesus monkey, sheep and rat but not in the rabbit. staining for vic-glycol groups was prominent in all ... | 1979 | 94996 |
| purification of mouse interferon by sequential chromatography. | two schemes for the purification of mouse interferon are described, based on the concerted application of various physicochemical and affinity/adsorption column chromatographic techniques. mouse interferon was purified to a final specific activity of 1.0--8.0 x 10(8) units/mg when first precipitated with ammonium sulphate and further processed by hydrophobic chromatography and adsorption chromatography on affi-gel 202 and controlled pore glass. it was purified to a final specific activity of 2.5 ... | 1979 | 95020 |
| comparison of antigenic properties among various strains of treponema hyodysenteriae. | agglutinin-absorption and precipitin-absorption studies demonstrated that three strains of treponema hyodysenteriae isolated from cases of swine dysentery were antigenically different from each other and also from a spirochete isolated from a clinically normal dog. each of the strains of t. hyodysenteriae also possessed two common antigens. | 1979 | 95077 |
| relationship between glucan-induced agglutination and glucan-binding ability of actinomyces viscosus cells. | 1979 | 95122 | |
| [structural and immunochemical studies of carp (cyprinus carpio l.) immunoglobulin. v. tryptic fragments of carp (cyprinus carpio l.) immunoglobulin m]. | carp igm, isolated from normal serum is more sensitive to trypsinization compared to a human myeloma protein igmgo. under the same conditions (treatment with trypsin at 56 degrees c for 30 min) carp igm was degraded to small, mostly dialysable peptides to a larger extent than igmgo. in both cases the fragmentation resulted in immunoelectrophoretically pure fab mu and fc mu fragments. the fab mu fragments of human igm (yield: 20% of used igm material) had a molecular weight of 54,000, the fc mu f ... | 1979 | 95144 |
| antigenic similarity between squamous cell carcinoma of horn (horn cancer) and normal bovine foetal tissues. | normal bovine foetal (liver and skin) and horn cancer tissue antigens were examined using double diffusion agar gel precipitation and immuno-electrophoretic tests to detect any cross reactivity among them. rabbit horn cancer antisera absorbed with normal bovine liver, skin and horn core epithelium antigens, when tested with foetal skin and liver (4 to 6 months of gestation), revealed the presence of 2 foetal antigens in horn cancer. immuno-chemically 2 of the horn cancer antigens were found to b ... | 1979 | 95358 |
| [antitumor activity and preclinical pharmacologic evaluation of pingyangmycin (author's transl)]. | 1979 | 95444 | |
| [effects of ddt and aldrin on swine cell line ib-rs-2]. | swine cells ib-rs-2 were exposed to 0,1-100 microgram/ml medium of ddt and aldrin for 48 hours. the data obtained showed that both compounds decreased cell growth. this effect depends on the concentration and on the time of cell exposition to the insecticides. these compounds also decreased the levels of cellular protein, rna and dna. the degrees of changes with aldrin were less than with ddt. | 1979 | 95479 |
| [morphological and histoenzymatic changes in the white rat testis after long-term administration of low doses of lindan and trichlorfon (author's transl)]. | 1979 | 95555 | |
| a receptor for polymerized human and chimpanzee albumins on hepatitis b virus particles co-occurring with hbeag. | a receptor for polymerized human serum albumin was demonstrated on dane particles as well as on 20-nm hepatitis b surface antigen particles, isolated from asymptomatic carriers of hepatitis b virus who were positive for hbeag. in contrast, such receptor was not born by 20-nm hepatitis b surface antigen particles obtained from carriers positive for antibody to hbeag. hepatitis b surface antigen particles with the receptor were heavier than those without, and when treated with pronase, they became ... | 1979 | 103774 |
| shigellosis and escherichia coli diarrhea: relative importance of invasive and toxigenic mechanisms. | shigellae and dysentery-like escherichia coli must invade the epithelium of the colon to cause disease which can present as dysentery, diarrhea, or both. this paper addresses the possible role of a shigella dysenteriae-like (shiga-like) toxin in the pathogenesis of shigellosis and e. coli diarrheal diseases. the possibility for such a role is suggested by the following observations: 1) diarrhea, considered to be a result of secretion of water by the small bowel, is frequently observed in shigell ... | 1979 | 104615 |
| quantitative determination of trinitroglycerin in human plasma. | we developed a simplified method for quantitative measurement of trinitroglycerin in human plasma using hexane extraction and analysis by gas-liquid chromatography with electron-capture detection. this assay was linear from 0.5-60 ng/ml. sensitivity and reproducibility were +/- 0.5 ng/ml. we used this assay to evaluate the pharmacodynamics of trinitroglycerin in 14 patients. maximum plasma levels were similar with trinitroglycerin given by constant intravenous infusion (1.6 +/- 0.4 ng/ml (sem)), ... | 1979 | 104804 |
| production of antivenom against detoxified taipoxin and immunochemical analysis of the alpha, beta and gamma subunits. | 1979 | 105431 | |
| [multiple molecular forms of erythrocyte carbonic anhydrase of sheep (author's transl)]. | three major forms ci, cii and cx and the minor component ci1v of ovine erythrocyte carbonic anhydrase have been identified in the ethanol chloroform extract of the hemolysate by electrophoresis on cellulose acetate and isoelectrofocusing. isolation of the four forms was achieved by chromatography on deae-sephadex a-50. comparative studies suggest that: (1) form ci1v is a modified form of ci, (2) form cx is ci plus glutathione and (3) forms ci and cii are isoenzymes which differ in their primary ... | 1979 | 106895 |