Publications

[parenteral use of a therapeutic vaccine in acute dysentery].		1979	377515
[analysis of merodiploid strains of sh. flexneri that have lost virulence].	episome f'13 introduced into the genome of a virulent sh. flexneri strain brought about changes in a number of properties of the recipient strain. the expression of these properties was not connected with the chromosome area allelic to the plasmid genome. these changes seem to be induced by the mobilization of the chromosome genes of e. coli. the loss of virulence in sh. flexneri strains carrying episome f'13 seemed to be the consequence of two reasons: the overlapping of kcpa gene by its domina ...	1979	377868
[search for host specificity systems in shigella using dd-series phages].	a total of 712 shigella strains were studied with the use of dysentery diagnostic phages dd ii, dd vi and dd vii in order to reveal the systems of host dna specificity. the study comprised 4 tests: mass screening by the intensity of phagolytic reaction of phages in various strains; and the determination of the parameters of adsorption. as a result, an effective modification and restriction systems were revealed in sh. sonnei 311 with the use of phage dd ii. bacteriophage dd vii was effectively r ...	1979	377869
[dynamics of the change in sensitivity of shigellae to gentamycin and cephaloridine in vitro].	the dynamics of the changes in the shigella sensitivity to gentamicin and cephaloridin was studied in vitro using liquid nutrient media with gradually increasing concentrations of the drugs. 50 passages were performed. it was found that shigella flexner and sonnei decreased their sensitivity to gentamicin to a little extent and remained middle sensitive. sensitivity of shigella flexner to cephaloridin also changed to a little extent, while shigella sonnei became moderately resistant.	1979	378113
[level and nature of the drug resistance of shigella flexneri].	characteristics of antibiotic resistance of 300 strains of shigella flexner 2a isolated from patients within 1976--1977 in the regions where these bacteria were very rare for a long period of time were studied. it was shown that most of the isolates were resistant to chloramphenicol (88.1 per cent), tetracycline (94.8 per cent), streptomycin (89.1 per cent), polymyxin m (82.4 per cent) and others. 46.5--61.6 per cent of the isolates were resistant to neomycin antibiotics. a high level of the res ...	1979	378114
vivo clearance of enteric bacteria from the hemolymph of the hard clam and the american oyster.	american oysters, crassostrea virginica, and hard clams, mercenaria mercenaria, were experimentally contaminated with escherichia coli, salmonella typhimurium, and shigella flexneri either by intracardial injection or via the natural route of ingestion. bacterial inactivation in the hemolymph was monitored for 72 h after exposure to these enteric pathogens at 20 and 6 degrees c. at 6 degrees c, both mean bacterial uptake by ingestion and subsequent clearance was singificantly lower that at 20 de ...	1979	378127
infectious mononucleosis associated with fatal beta hemolytic streptococcal infection.		1979	378507
enzyme-linked immunosorbent assay for immunoglobulin g and immunoglobulin a antibodies to shigella flexneri antigens.	an enzyme-linked immunosorbent assay has been developed to detect class-specific antibodies to shigella flexneri lipopolysaccharide antigens. this enzyme-linked immunosorbent assay system has been used to measure antibodies present in serum or intestinal secretions without further purification. it is considerably more sensitive than passive hemagglutination, allowing detection of as little as 1.3 ng of specific immunoglobulin g antibody per ml in immune sera. optimal conditions for this assay ar ...	1979	378853
molecular characterization of plasmids from virulent and spontaneously occurring avirulent colonial variants of shigella flexneri.	spontaneous transition of shigella flexneri from t- to o-type colonies with concomitant loss of virulence dose not appear to be accompanied by a change in any of the four plasmic species found in the virulent parent.	1979	378861
monocyte function in psoriasis.	monocytes derived from the peripheral blood of psoriatic patients demonstrated a significantly higher phagocytic capacity (36 to 40%) for both 125i-labeled shigella flexneri and 125i-labeled staphylococcus albus compared with monocytes from healthy subjects. monocytes from psoriatic patients showed a 2-to-4fold increase in bactericidal capacity against s. albus when compared with normal monocytes. however, the bactericidal capacity of monocytes from diphylline-treated patients did not differ fro ...	1979	379240
[a dysentery epidemic among tunisia travelers].		1979	379657
[effect of metabolism products of shigella sonnei, sh. flexneri and sh. shigae on proteolytic activity of the organism connective tissue].	the activity of proteolytic enzymes, neutral proteinases and cathepsins e+d, was determined in homogenates from the tissues of capsules formed around diffusion chambers with shigella (shigella sonnei, sh. flexneri, sh. shigae) 1, 2, 3, 5 and 10 days after their implantation to the abdominal cavity of rabbits. the specific proteolytic activity in the capsule tissues in the experimental variants is higher in all the studied periods than in the control and its singularities depend on the microbe sp ...	1979	380094
[sh. flexneri population heterogeneity according to the cellular fatty acid makeup].	the composition of fatty acids in the cells of 100 clones of sh. flexneri, strain 9054, isolated from a dysentery patient was studied by the method of gas chromatography. fatty acid composition in 75 clones was similar to the fatty acid composition of the initial culture: 25 clones differed to a variable degree from the prevailing group of clones in the content of unsaturated and cyclopropane fatty acids and, to a considerably lesser extent, in the content of palmitic acid and a number of other ...	1979	380239
[data to substantiate the early immunological diagnosis of dysentery].	the interaction of the whole blood from patients with dysentery and gastrointestinal diseases of non-dysenteric etiology, with the causative agents of dysentery, sh. sonnei and sh. flexneri, and saprophytic, staphylococci labeled with radioactive isotopes was studied in vitro. in dysentery an increase in the capacity of the blood for shigella fixation was observed from the beginning of the disease. during the 1st week of the disease this reaction was strictly specific and accompanied by a decre ...	1979	380241
[course of dysentery and the specific alteration of the neutrophils in children in the use of monomycin and a diet with an increased protein content].	acute dysentery mainly due to shigella sonnei and dynamics of the neutrophil damage index (ndi) of the blood were studied in 80 children at the age of 1 to 14. 20 children (group 1) were treated with monomycin under conditions of a diet with an excessive content of protein (by 25% higher than the physiological norm). 60 children or 3 groups of 20 children each were not subject to such conditions and were considered as control groups. reduction in the time of recovery (by 4 days) and bacteriologi ...	1979	380456
study on the possible entry of bacterial endotoxin and prostaglandin e2 into the central nervous system from the blood.	1 a study has been made of the possible entry of 51cr-bacterial endotoxin and [5,6,8,11,12,14,15(n)-3h]-prostaglandin e2 ([3h5-pge2) into the cns of the anaesthetized cat. 2 no radioactivity was detected in perfusates of the preoptic-anterior hypothalamus or in the cerebrospinal fluid (c.s.f.) in vivo, or in brain tissue post mortem following intracarotid infusion of 51cr-bacterial endotoxin. 3 intracarotid administration of [3h]-pge2 resulted in the entry of radioactivity into the cns of endoto ...	1979	380709
age-dependent macrophage functions in new zealand black mice.		1979	380820
somatic antigens of shigella. the structure of the specific polysaccharide of shigella newcastle (sh. flexneri type 6) lipopolysaccharide.	the specific polysaccharide was obtained from the lipopolysaccharide of shigella newcastle by mild acid hydrolysis and further purified by permeation chromatography on sephadex g-50. it was found to consist of l-rhamnose, 2-acetamido-2-deoxy-d-galactose, d-galacturonic acid residues and o-acetyl groups in the molar ratios of 2:1:1:1. on the basis of 1h and 13c nuclear magnetic resonance spectroscopy, methylation analysis, partial acid hydrolysis, smith degradation, and chromium trioxide oxidatio ...	1979	381001
shigella infection of henle intestinal epithelial cells: role of the bacterium.	epithelial cell infection by shigella flexneri 2a was studied in an in vitro model system. using the henle 407 human intestinal epithelial cell line as host cells, a standardized experimental protocol which allowed quantitative measurement of infection was developed. intravellular residence of infecting organisms was confirmed by indirect fluorescent-antibody staining of unfixed and methanol-fixed (henle 407) cells and by quantitative bacteriological culture of disrupted host cells after infecti ...	1979	381204
[diagnosis of acute appendicitis in patients suffering from diarrhea].		1979	382628
mitomycin c stimulates production of a toxin in shigella species that causes morphological changes in chinese hamster ovary cells.	shigella dysenteriae produced a toxin that caused morphological changes in chinese hamster ovary cells which was different from the neurotoxin (y. takeda, k. okamoto, and t. miwatani, infect. immun. 18:546--548, 1977). it was found that the toxin was produced not only by s. dysenteriae but also by s. flexneri, s. boydii, and s. sonnei. the production of the toxin was stimulated by the addition of 1 microgram of mitomycin c per ml to the culture in the early logarithmic growth phase.	1979	370009
structural studies on the hexose region of the enterobacteriaceae type r3 core polysaccharide.	the structure of the hexose region of the enterobacteriaceae type r3 core polysaccharide, which is the common core in shigella flexneri and some escherichia coli lipopolysaccharides (lps), has been investigated. the principal method used in these studies involved methylation analysis of the original and modified materials. the polysaccharide was modified by n-deacetylation-deamination and by smith degradation. as a result of these studies, the following structure is proposed: alpha-d-glcp-(1 lea ...	1979	371805
the effect of endotoxin-induced intraocular inflammation on the rat lens epithelium.	intraocular inflammation induced by an intravitreal injection of shigella endotoxin into the rat eye produces early changes in the number of dividing cells of the lens epithelium and affects the organization of the meridional rows. a depression in mitotic activity in the germinative zone is observed during the first 24 hr after injection. at 48 hr, despite the continued mitotic inhibition in the germinative zone, an increase in cell division occurs in the central zone. by 72 hr, the germinative ...	1979	372124
[shigellosis].		1979	372830
[chimpanzee as a pet: cause of a shigella infection].		1979	372831
[properties of the r plasmids of sh. flexneri strains isolated in bulgaria].	the study of 3,237 sh. flexneri strains isolated in bulgaria revealed that 50.72% of them were resistant to antibiotics. 95.88% of the antibiotic-resistant strains were found to have r factor of incompatibility groups f, i or n. the plasmids of incompatibility group f had the property fin+, and the plasmids of groups i and n had the property fin-. r plasmids were divided into 4 groups by their ability for phage restriction.	1979	373338
[comparative evaluation of different globulin preparations and of the means for blood sensitization in obtaining antibody erythrocytic diagnostica].	in comparing the hemosensitizing activity of various immunoglobulin preparations with different methods of erythrocyte loading the greatest activity and specificity was revealed in igg isolated by means of deae-sephadex a-50. the method of erythrocyte sensitization with the use of alizarin blue indicator was more advantageous in respect to sensitivity and specificity of sh. sonnei and newcastle indication over boyden's, jandl and simmons', bing's methods.	1979	373342
[antibiotic resistance of shigella in different regions of the ussr].	shigella were most sensitive to polymyxin ceporin, ampicillin, neomycin and furazolidone and resistant to chloramphenicol, tetracycline and streptomycin. shigella resistant simultaneously to two or three drugs mainly to tetracycline + chloramphenicol, tetracycline + streptomycin and tetracycline + chloramphenicol + streptomycin were most frequent. the frequency of the shigella strains carrying r-plasmids increased from 28 per cent in 1969--1970 to 72.6 per cent in 1977. the shigella strains isol ...	1979	373617
the enzymes of the galactose cluster in saccharomyces cerevisiae. purification and characterization of galactose-1-phosphate uridylyltransferase.		1979	387754
synthesis and properties of fluorescent nucleotide substrates for dna-dependent rna polymerases.	a new class of fluorescent nucleotide analogs which contain the fluorophore 1-aminonaphthalene-5-sulfonate attached via a gamma-phosphoamidate bond has been synthesized. both the purine and pyrimidine analogs have fluorescence emission maxima at 460 nm. cleavage of the alpha-beta-phosphoryl bond produces change in both the absorption and fluorescence emission spectra. the fluorescence of the pyrimidine analogs is quenched; cleavage of the alpha-beta-phosphoryl bond of the utp analog produces abo ...	1979	387781
api and minitek systems in identification of clinical isolates of anaerobic gram-negative bacilli and clostridium species.	a comparison of the api and minitek methods of biochemical testing was made on a variety of anaerobic bacteria. although api and minitek results were not compared to more standardized or conventional procedures of identification, multiple repeat testing of the two systems was done on routine clinical isolates and known organisms to determine (i) whether the reactions were reliably consistent, (ii) the ease of reading the two systems with respect to the frequency of questionable results, and (iii ...	1979	387809
characterization of plasmids from antibiotic-resistant shigella isolates by agarose gell electrophoresis.	gel electrophoresis of dna from 95 clinical isolates of shigella sonnei and shigella flexneri resistant to antibiotics revealed a heterogeneous plasmid population. most of the plasmids were smaller than 6 megadaltons (mdal). six s. sonnei isolates with the most common antibiotic resistance pattern were characterized. they had two plasmids in common: one was a self-transmissible fi+ plasmid of 46 mdal encoding resistance to streptomycin and sulphafurazole. in addition, several cryptic plasmids ra ...	1979	387914
[clinical and pathogenetic comparisons with allergization in flexner and sonne dysentery].		1979	388063
[comparative characteristics of the clinical course of flexner and sonne dysenteries during the warm and cold periods of the year].		1979	388064
[comparative effectiveness of the treatment of acute dysentery].		1979	388065
shigella dysenteriae, sh flexneri, and sh boydii infections in england and wales: the importance of foreign travel.		1979	389342
macrophage functions in high and low cancer incidence strains of mice. a comparative study.		1979	389688
[structure of drug resistant bacilli (author's transl)].		1979	390191
human plasma angiotensinogen: a review of purification procedures.	the current status of the purification and characterization of human angiotensinogen is reviewed. one problem encountered in the past has been the copurification of a protein with similar porperties. this protein has tentatively been designated alanine-protein. an efficient separation of angiotensinogen and alanine-protein was obtained on a zinc chelate column. alanine-protein has been purified and its amino acid and carbohydrate composition determined. the cooh-terminal amino acid and the nh2-t ...	1979	390363
[cyclical nature and the prediction of the dynamics of the epidemic process in different types of dysentery].		1979	390937
patterns of shigella species and serotypes in east africa.		1979	391541
[intestinal flora and bile acids metabolism -- influence of bile acids on rejection of shigella flexneri 2a from the intestine (author's transl)].		1979	392126
[effect of intercurrent pathology on the immune response of the child's body in dysentery].		1979	392428
[characteristics of the outbreak and control of an epidemic of bacillary dysentery of hydric origin].	in december 1978, an unexpected outbreak of acute gastroenteritis occurred in a shoe factory. the clinical, epidemiological and laboratory investigations established the hydric origin of the dysentery due to shigella flexneri 3 a, caused by the illicit communication of the drinking water and industrial water mains. the antiepidemic measures promptly taken arrested the outbreak in three days ; there were no secondary, contact cases.	1979	394270
[studies concerning dysenteric infections in a closed children's community before and after antidysenteric vaccination. i. epidemiological considerations on acute intestinal infections].	in the closed children's community studied between 1 jan. 1976 and 13 june 1977, a high proportion (54%) of the total number of acute intestinal infections was of dysenteric etiology, i.e. 46,9% in the 0--1 year age-group and 21,1% in the 1--3 years age-group, the dominant shigella subtype being represented by shigella flexneri 2a (25.1%). as only 37.2% of the total number of dysentery cases were manifested by enterocolitis and a high proportion (33.3%) ran a chronic course, the disease was not ...	1979	394271
lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate.	rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (ippv) for 60 min. tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. the quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. immature animals with low lung-thorax complianc ...	1979	394314
[shigellosis in tananarive (madagascar). ii : bacteriologic and therapeutic features (author's transl)].	in acute dysenteries or diarrhoeas shigellae are the bacterial organisms which are the most frequently isolated from coprocultures. the most frequent sub-group is sub-group b (s. flexniri). in vitro, shigellae are sensible to all antibiotics but often resistant to sulfamids. treatment is not difficult.	1979	395407
relationship between blood flow velocity in the choroid and intraocular pressure in rabbits.	by using thermistors for calorimetry to monitor blood flow velocity in the choroid of the anaesthetized rabbit, it was found that an elevation of intraocular pressure reduced the choroidal blood flow. the relationship between the ratio of perfusion pressure to intraocular tension (x) and the reciprocal value of the percentage of blood flow velocity (l/y) showed a curve convex towards the pressure axis. on a log-lin scale the graph was linear. a significant linear correlation with a coefficient o ...	1979	419976
skeletal changes in the condylar cartilage of the neonate mouse mandible.	histological and histochemical qualitative and quantitative determinations are provided concerning the skeletal changes taking place in the growth center of the mandibular condyle in the neonatal icr mouse. this study followed the changes in both the major matrical components (collagen, acidic glycosaminoglycans and glycolipids) as well as in the various cartilage cells throughout the maturational period of the neonatal condyle. it was found that the transformation of neonatal condylar cartilage ...	1979	420892
projection from the vestibular nuclei to the inferior olive in the cat: an autoradiographic and horseradish peroxidase study.	injections of horseradish peroxidase (hrp) in the inferior olive of 13 cats resulted in the labeling of neurons in the medial (mvn) and descending vestibular nuclei (dvn) as well as in subgroups g, p.h., s.v., x and z. the contribution of groups p.h. and z. could not be definitively established. injections of triated leucine in the vestibular nuclei and adjacent reticular formation in 4 cats indicated that the previously identified vestibular nuclei and subgroups project bilaterally to the dorso ...	1979	421137
the canine eye: the vessels of aqueous drainage.	lumenal castings of canine vessels of aqueous drainage, prepared by microvascular injection of room-temperature vulcanizing silicone or batson's methacrylate corrosion compound no. 17, were viewed with a stereo dissecting microscope and by scanning electron microscopy. the pathways for aqueous drainage in the dog appear to extend radially from the interstices of the filtering meshwork, through the deep intrascleral venous plexus, to the midscleral venous circle of hovius, which also serves choro ...	1979	422328
high pressure liquid chromatographic determination of nitrofurazone in milk.	a rapid high pressure liquid chromatographic (hplc) screening method for the quantitative determination of nitrofurazone in milk has been developed. the drug is extracted with ethyl acetate from a 2.0 ml milk serum sample, the organic layer is evaporated to dryness, and the residue is dissolved in the mobile phase and injected into the liquid chromatogarph. a reverse phase mubondapak c18 column is used with monitoring at 365 nm. the detection limit is 5 ppb and recoveries are 57--67%. mass spect ...	1979	422501
comparison of the membrane composition of spiroplasma citri and the corn stunt spiroplasma.	components of membranes isolated from spiroplasma citri and corn stunt spiroplasma grown at 28 degrees c were analyzed. on a protein basis, lipid phosphorus was lower and cholesterol was higher in s. citri. only minor differences between the two species were found in fatty acid composition, reduced nicotinamide adenine dinucleotide diaphorase, and adenosine triphosphatase.	1979	422510
incidence and pathological features of spontaneous tumors in athymic nude mice.	systematic observation of 1141 nude mice (swiss background [corrected] strain) that received human tumor transplants revealed 24 spontaneous tumors, 18 of lymphoreticular origin and 6 pulmonary adenomas. spontaneous tumors were seen at an average age of 9.1 months, and 22 of the tumors were seen only in that fraction of our group (324 mice) surviving for 5 months or more (22 of 324 x 100 = 6.8%). transplantation of these tumors to other nude mice was successful in three of five cases. mice trans ...	1979	427772
multi-element analysis of the rat hippocampus by proton induced x-ray emission spectroscopy (phosphorus, sulphur, chlorine, potassium, calcium, iron, zinc, copper, lead, bromine, and rubidium).	a technique for multi-element analysis of brain tissue by proton induced x-ray emission spectroscopy (pixe) is described and data from analysis of fixed and unfixed samples from rat hippocampus, neocortex, amygdala, and spinal cord is presented and commented on. the atoms present in the tissue are bombarded with protons which causes the ejection of electrons from the inner shells. when the "holes" are refilled with electrons from outer shells, x-ray quanta characteristic for each element are emi ...	1979	429203
contribution of adrenal medulla, spleen and lymph, to the plasma levels of dopamine beta-hydroxylase and catecholamines induced by hemorrhagic hypotension in dogs.		1979	438992
the problem of interaction of shigella with epithelial cells.	a review and analysis of data on the investigation of factors concerning the initial events of interaction of shigella with epithelial cells: attachment of penetration are presented. in the experiments with 3h-labeled bacteria it was shown that although common pili confer adhesive properties to bacteria but the penetration of shigella into the cell is not increased. it was stated that lps of shigella o antigen plays an important role not only in interaction with cellular and humoral factors of t ...	1979	442880
carcinogenic hydrocarbons increase the acceptance of transfer ribonucleic acid for methionine.		1979	444273
thermodynamics and kinetics of the interaction of copper (ii) ions with native dna.		1979	444636
dissociations between the effects of lsd on behavior and raphe unit activity in freely moving cats.	the hypothesis that the action of hallucinogenic drugs is mediated by a depression of the activity of brain serotonergic (raphe) neurons was tested by examining the behavioral effects of d-lysergic acid diethylamide (lsd) while studying the activity of raphe neurons in freely moving cats. although the results provide general support for the hypothesis, there were several important dissociations. (i) low doses of lsd produced only small decreases in raphe unit activity but significant behavoiral ...	1979	451617
studies on conformational changes in f-actin of glycerinated muscle fibers during relaxation by means of polarized ultraviolet fluorescence microscopy.	by means of polarized ultraviolet fluorescence microscopy the conformational changes of f-actin occuring in glycerinated muscle fibers of rabbit and barnacle (balanus rostratus hock.) under the influence of adenosine triphosphate in the presence of ethylene glycol bis(beta-amino-ethyl ether)-n,n'-tetraacetic acid were discovered. these changes seem to be located near the surface of the globules thus hampering the penetration of univalent iones and neutral molecules into the f-actin macromolecule ...	1979	470613
[biomass accumulation by polyploid forms of candida guilliermondii yeasts].	under the action of a mitotic poison (acenaphthene), the haploid culture of candida guilliermondii assimilating n-alkanes yielded a polyploid form whose cells were four times larger, on the average, than in the haploid culture. when the pure culture was grown under stationary conditions in media with glucose, the economical coefficient, i. e. the ratio between the assimilated glucose and the accumulated biomass, was by 16, 47 and 157% higher in the polyploid culture than in the haploid one after ...	1979	470627
[exopolysaccharide and proteolytic enzyme synthesis by m-, s- and r-forms of mycobacterium lacticolum].	the composition of exocellular polysaccharides was studied in the m, s and r variants of mycobacterium lacticolum 104. the exoglycans of the m and s variants were found to be rather similar but differ considerably from the exoglycan of the r form. the polysaccharides of the m and s cells contained glucose, mannose, galactose, and pyruvic acid; the exoglycan of the r cells contained also the fourth sugar arabinose, but lacked pyruvic acid. the specific rotation of the polysaccharides from the m, ...	1979	470628
an xyy man.	this case report describes a young man with a 47, xyy karyotype who was convicted of arson. he suffered from a cardiac disorder which may well have been part of the xyy syndrome rather than a chance association. his abnormal karyotype was disclosed in court and used by the defence in a plea in mitigation.	1979	497632
cellular aspects of muscle growth: myogenic cell proliferation.		1979	500507
purification and chemical characterization of antigens from sheep erythrocytes.	a mixture of glycoproteins and glycolipids was solubilized from sheep erythrocytes membranes under the effect of high ionic strength (2 m nacl, 0.5 m tris). several antigenic fractions could be purified from the mixture using gel filtration on sephadex g-200 and block electrophoresis on pevikon c870; two fractions were found to raise antibodies in a primary reaction and these antibodies effectively sensitized erythrocytes to lysis by complement. the majority of other fractions elicited a weaker ...	1979	511033
the preoptic region of the merino sheep.		1979	511043
[first results obtained in man with ethinyl estradiol sulfonate given for various indications (proceedings)].		1979	515140
[serum enzymatic activity in acute injury to the renal parenchyma].	studied was the activity of the serum enzymes lap, ce, aph, sph, and guanase as well as the isoenzymes of the unspecific esterases and aph in guinea pigs treated with potassium bichromate. morphologically and histopathologically, an acute injury of the kidney parenchyma was found, being in close correlation with the size of lesions and these enzymes' activity. the activity of aph, sph, and ce rose, and that of lap and guanase did not change. these enzymes proved to form an appropriate constallat ...	1979	516440
[allergenic and anaphylactoid properties of carcinostatic compounds of platinum].	different effects of platinum salts on the organism were studied comparatively. the toxic effect was estimated by ld50; the carcinogenic one--by the action on ehrlich ascites tumor; the anaphylactoid effect was evaluated by the degree of the arterial pressure fall, the development of bronchospasm and an increased blood histamine level in cats under intravenous injection of platinum salts. the sensitization action of platinum salts was assessed on guinea pigs. all these effects are found to be de ...	1979	516565
[assimilation of certain amino acids administered to animals of different ages].	changes in the content of some amino acids (tryptophane, lysine, histidine and arginine) in blood plasma were studied in young and old rabbits administered lysine, arginine and urea into the stomach. a decrease in utilization rate of the test amino acids in old animals, their interdependence and the effect of urea administration on the lysine level in blood serum at a relatively stable content of tryptophane and histidine were established. a conclusion is drawn about the necessity of taking into ...	1979	516594
[dry adapting additive and its use in dairy products for approximating the composition of human milk].	the paper concerns a procedure for a new product, dry adapting additive (daa), designed for manufacture of liquid substitutes of breast milk under industrial conditions. the chemical composition of adapted milk mixtures is compared to that of breast milk. procedures for adapted mixtures to be manufactured at city milk kitchens, food concentrate factories and under domestic conditions have been developed, with the mixtures being widely tried on clinical basis.	1979	516610
histologic diagnosis of diseases of malabsorption.	the diagnoses which may be arrived at by examination of peroral small bowel mucosal biopsy specimens are presented. celiac sprue, unclassified sprue (refractory sprue), infectious gastroenterititis, stasis syndrome and kwashiorkor have a severe mucosal lesion. other clinical conditions are required to establish the diagnosis in these diseases. a number of diseases have specific diagnostic features. included are whipple's disease, abetalipoproteinemia, collagenous sprue, primary intestinal lympho ...	1979	517556
the kidney and ochratoxin a.		1979	520974
competition among hexoses for hepatocellular uptake in the perfused liver of rat [proceedings].		1979	521922
[on the stiffness of human tibialis anterior muscle during voluntary contraction (author's transl)].		1979	522295
the mast cell: iii. distribution and maturation in various organs of the young rat.	the changing population-density of mast cells in various organs was plotted for rats aged 1/2 to 90 days and correlated with histochemical studies on the stage of maturation of cells. mast cells are present at birth in liver and spleen and are particularly associated with foci of haemopoiesis. in bone marrow mast cells are absent at birth but become progressively more numerous with increasing age of the animal. the association of mast cells firstly with foci of extramedullary haemopoiesis and se ...	1979	523184
[receptors of human red blood cells for anti-tah and anti-ahp in the course of intravascular aging].	human o-erythrocytes aged in situ do not expose free receptors for anti-t agglutinin of arachis hypogea. new receptors for concentrated anti-a agglutinin of helix pomatia are manifested but are lost again in the course of further ageing of the cells in situ. a remasking of exposed receptors for anti-tah and anti-ahp byautologous, strongly binding globulins is supposed. these globulins could constitute the decisive signal for the autologous phagocytosis of senescent red blood cells.	1979	525143
reticulo-rumen motility in the chronically vagotomized sheep [proceedings].		1979	529098
adrenergic responses to transmural electrical stimulation of the guinea-pig gall-bladder [proceedings].		1979	529152
lipid metabolism in rats fed a diet with high citrus pectin content.		1979	532387
[lodgement of the intraventricular catheter into cerebral parenchima in infantile hydrocephalus (author's transl)].	ten cases of hydrocephalus of diverse ethiology, treated with ventriculo-peritoneal shunt are presented. in following controls it was observed that extreme of the catheter was located in cerebral parenchima. these features were followed of minimal clinics alterations and electroencephalographic focal manifestations. the pathogenesis of the complication due to the findings in the computerized axial tomography (cat) and the real value in the diagnosis of this complication are analized.	1979	533055
identification of a new allele of es-i segregating in an inbred strain of mice.	a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation.	1979	540008
effect of sodium hydroxide upon protein binding to filter paper disks and its significance in the determination of protein in colorimetric and radioisotopic assays.		1979	543545
restoration of metabolic cooperation in heterokaryons between hgprt-deficient mouse a9 fibroblasts and chick embryo erythrocytes.	genetic determinants of metabolic cooperation were studied by fusing chick erythrocytes to hgprt- mammalian cells. heterokaryons were then tested for their ability to incorporate [3h]hypoxanthine and to transfer radioactive material to hgprt- recipient cells. chick erythrocytes (ce) have nuclei which are inactive but contain the hgprt gene and some cytoplasmic hgprt enzyme activity. they are unable, however, to cooperate with hgprt- cells. of the two mammalian cell lines used, the human gm29 lin ...	1979	545717
convergence of human age-sex distributions to an equilibrium-state age-sex distribution.		1979	545730
beta-[1-phenyl-5-bis(beta-chloroethyl)-amino-benzimidazolyl-(2)]-dl-alanine (zimet 3164): an immunosuppressant without marked anti-cancer effect.	zimet 3164 inhibited the growth of sarcoma 180 p, sarcoma 180 g, and walker 256 carcinosarcoma, but was unable to prolong the survival time of mice bearing ehrlich ascites carcinoma or the leukaemias l 1210 and laj i to a worthwhile extent. the primary and secondarantly suppressed in mice. the drug exerted maximum effect when given on days--2 to +2 relative to antigenic stimulus. administration exclusively prior to immunization induced only moderate immunosuppression while injection afterwards f ...	1979	546175
some chemical and nutritional properties of acylated fish protein.		1979	546957
correlation between gross observations of tumors and neoplasms diagnosed microscopically in carcinogenesis bioassays in rats.	microscopic diagnoses of spontaneous and induced neoplasms in f344 rats in two carcinogenesis bioassays were correlated with the gross observations made at the time of necropsy. the results for a negative and a positive compound with reference to carcinogenicity, indicate that of the gross descriptions indicative of tumors, 37 percent and 24 percent respectively, were not diagnosed as neoplasms microscopically. however, some of the gross lesions were diagnosed histologically as nonneoplastic les ...	1979	547015
[lectins as reagents for the differentiation of serum enzymes. lectins as reagents, i. (author's transl)].	lectins from canavalia ensiformis, phaseolus vulgaris, and triticum vulgare react with arylamidase, alkaline phosphatase, gamma-glutamyltransferase, and cholinesterase of human sera by formation of enzymatically active, mostly insoluble complexes. arylamidase, alkaline phosphatase, and cholinesterase react more intensely in sera of healthy people than in sera of patients with liver and neoplastic diseases. arylesterase is bound to a distinct degree only by concanavalin a. the enzymes mentioned a ...	1979	547035
[electron microscopical evidence of spiroplasma citri in nucleus of infected testplants (author's transl)].	this is the first report for the evidence of mycoplasmas in an organelle of a plant cell. spiroplasma citri was detected by electron microscopy in the nucleus of a phloem parenchyma cell of chrysanthemum carinatum schousboe plants, inoculated experimentally by euscelis plebejus fall.	1979	549392
construction of haloaromatics utilising bacteria.		1979	551259
aspartame: assessment of developmental psychotoxicity of a new artificial sweetener.		1979	551307
postnatal behavioral changes in prenatally irradiated rats.	rats were exposed on gestational day 15 to 125 r x-irradiation, a treatment known to severely alter brain morphology. at 4-6 weeks of age the behavior of these animals was studied using two methods: (1) measurement of circadian locomotor activity, (2) photographic analysis of behavioral acts. the circadian locomotor activity of irradiated rats was similar to that of controls tested individually or as groups in a residential unit. after morphine sulfate, 2 mg/kg, the increase in locomotor activit ...	1979	551312
studies on the inhibitory effects of zinc heptanoate on microorganisms.	inhibitory effect of zinc heptanoate was observed on different cultures of bacteria and fungi. growth of all the bacteria was inhibited by the compound. greatest inhibition was seen in the case of staphylococcus albus, streptococcus pyogenes, shigella dysenteriae, shigella sonnei, shigella flexneri, salmonella typhi, s. paratyphi a, s. paratyphi b, vibrio cholerae, corynebacterium diphtheriae, and e. coli whereas least inhibition was found in the case of staphylococcus aureus. in triethanolamine ...	1979	553835
antigenic similarity of morphologic type ciii1 bacteriophages.		1979	397728
phagocyte functions in familial mediterranean fever.	monocytes derived from peripheral blood of patients with familial mediterranean fever (f.m.f.) demonstrated lower phagocytic capacity for shigella flexneri and depressed bactericidal activity against s. albus when compared to monocytes from healthy individuals. treatment of patients with colchicine did not alter these functions. on the other hand, chemokinesis of pmn of f.m.f. patients was enhanced especially during attacks. colchicine treatment decreased significantly the pmn chemotactic migrat ...	1979	397753
comparison of some shigella flexneri (escherichia coli) hybrids in cross agglutination and agglutinin absorption tests.	antigenic structure of lac+ hybrids selected from escherichia coli x shigella flexneri crosses was compared in the cross agglutination and absorption tests. identity of the hybrids from the recipients of serotype 2a and variant y was proved, as well as from serotypes 1b and 4b. the latter hybrids were coupled with shigella flexneri strains 3a, 3b and 3c. the hybrids appeared almost identical with serotype 3c.	1979	398206
histoautoradiographic investigation of the invasive dissemination of ehrlich ascites tumor cells through the organs of the mouse.	in this paper the attempt has been pursued to quantify by a well planned experimental technique the ability of the neoplastic cells to spread around in vivo through various organs of laboratory animals. by making use of the histoautoradiographic techniques the incorporation of 3h thymidine either by the normal and by the neoplastic cells has been investigated at many different anatomical sites in ehrlich ascites tumor-bearing mice. the method has been shown to be well suited also for the quantit ...	1979	398216
the intestinal flora and infant botulism.	the intestinal flora of experimental animals interferes with infection by species of salmonella and shigella. protection against infection with these organisms appears to be related to high concentrations of volatile acids, low ph, and low oxidation-reduction potential of the intestinal contents of animals with an intact flora. there are no data to show that the flora influences colonization of the intestine with clostridial species, but indirect evidence suggests that the intestinal flora may b ...	1979	399374