Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| optimum designs for non-linear mixed effects models in the presence of covariates. | in this article, we present a new method for optimizing designs of experiments for non-linear mixed effects models, where a categorical factor with covariate information is a design variable combined with another design factor. the work is motivated by the need to efficiently design preclinical experiments in enzyme kinetics for a set of human liver microsomes. however, the results are general and can be applied to other experimental situations where the variation in the response due to a catego ... | 2017 | 28131108 |
| sexual and marital dysfunction in women with gynecologic cancer. | sexual dysfunction can be a long-term issue for women with gynecologic cancer. this study assesses the extent of sexual and marital dysfunction women face following treatment of a gynecologic cancer. | 2017 | 28129243 |
| sports-related emergency preparedness in oregon high schools. | best practice recommendations for sports-related emergency preparation include implementation of venue-specific emergency action plans (eaps), access to early defibrillation, and first responders-specifically coaches-trained in cardiopulmonary resuscitation and automated external defibrillator (aed) use. the objective was to determine whether high schools had implemented these 3 recommendations and whether schools with a certified athletic trainer (at) were more likely to have done so. | 2017 | 28129072 |
| [comparing the activity of multiple sclerosis (ms) at the minute and at 20 minutes of gadolinium application in magnetic resonance imaging (mri) of the brain?] | the aim was to compare active disease in patients diagnosed with multiple sclerosis, brain by mri after gadolinium application at one minute and 20 minutes. a longitudinal, prospective, observational, analytical and comparative study was conducted in 18 patients over 18 years of age diagnosed with multiple sclerosis (ms). an analysis was made for each patient, watching for inflammatory activity in ms lesions, comparing the results to one minute and 20 minutes after the application of gadolinium. ... | 2017 | 28128810 |
| correlation-based linear discriminant classification for gene expression data. | microarray gene expression technology provides a systematic approach to patient classification. however, microarray data pose a great computational challenge owing to their large dimensionality, small sample sizes, and potential correlations among genes. a recent study has shown that gene-gene correlations have a positive effect on the accuracy of classification models, in contrast to some previous results. in this study, a recently developed correlation-based classifier, the ensemble of random ... | 2017 | 28128419 |
| ehtic study: evaluation of a new hemostatic agent based on tissue factor in skin grafting procedures. | excessive bleeding is a major concern in scar debridement and grafting procedures. tt-173 is a new topical hemostatic agent based on recombinant human tissue factor that has shown promising results in patients who underwent tooth extraction. ehtic study sought to evaluate the efficacy and safety of tt-173 to reduce the bleeding in donor sites of skin grafting procedures. | 2017 | 28126447 |
| measurement of clozapine, norclozapine, and amisulpride in plasma and in oral fluid obtained using 2 different sampling systems. | there is a poor correlation between total concentrations of proton-accepting compounds (most basic drugs) in unstimulated oral fluid and in plasma. the aim of this study was to compare clozapine, norclozapine, and amisulpride concentrations in plasma and in oral fluid collected using commercially available collection devices [thermo fisher scientific oral-eze and greiner bio-one (gbo)]. | 2017 | 28125503 |
| translationally-controlled tumor protein activates the transcription of oct-4 in kidney-derived stem cells. | the molecular mechanisms underlying translationally-controlled tumor protein (tctp) in the activation of octamer-binding transcription factor 4 (oct-4) in kidney-derived stem cells have not been characterized. the aim of the present study was to identify the transcriptional activation of oct-4 by tctp in kidney-derived stem cells. homology-directed repair cdna inserted into fisher 344 transgenic (tg) rats and the mouse strain 129/svj were used for the experiments. diphtheria toxin (dt; 10 ng/kg) ... | 2017 | 28123502 |
| protective effect of phosphates and fluoride on the dissolution of hydroxyapatite and their interactions with saliva. | this study aimed to investigate the effect of phosphates and fluoride, alone or in combination, and the influence of salivary pellicle on hydroxyapatite (ha) dissolution. the baseline dissolution rate of ha discs was measured using a ph-stat system (0.3% citric acid, ph 3.2). in the first series of experiments, ha discs (n = 8/group) were treated with: a placebo solution (pla, deionised water); sodium trimetaphosphate (tmp), sodium tripolyphosphate (tri) and sodium pyrophosphate (pyro) at 1 or 8 ... | 2017 | 28122365 |
| prevalence and risk factors for atherosclerotic carotid stenosis and plaque: a population-based screening study. | atherosclerotic carotid stenosis (acs) is a major cause of ischemic stroke. screening for asymptomatic acs is important to identify the patients who require longitudinal surveillance, medication, or endovascular surgery. the aim of this study was to assess the prevalence and risk factors for acs and carotid plaque (cp) in korea using a population-based screening study.we recruited participants during visits to several community welfare centers in korea. the baseline characteristics of the study ... | 2017 | 28121957 |
| does navigation improve pedicle screw placement accuracy? comparison between navigated and non-navigated percutaneous and open fixations. | the aim of our study was to assess how a preoperative computed tomography (ct)-based navigation system affected the correctness and safety of transpedicular screw insertion, compared with standard techniques. | 2017 | 28120086 |
| radiology reports with hyperlinks improve target lesion selection and measurement concordance in cancer trials. | radiology reports often lack the measurements of target lesions that are needed for oncology clinical trials. when available, the measurements in the radiology reports often do not match those in the records used to calculate therapeutic response. this study assessed the clinical value of hyperlinked tumor measurements in multimedia-enhanced radiology reports in the pacs and the inclusion of a radiologist assistant in the process of assessing tumor burden. | 2017 | 28112557 |
| causes of poor outcome in patients admitted with good-grade subarachnoid haemorrhage. | surgical risk in patients with unruptured aneurysms is well known. the relative impact of surgery and natural history of subarachnoid haemorrhage (sah) on patients in good clinical condition (world federation of neurological surgeons [wfns] grades 1 and 2) is less well quantified. the aim of this study was to determine causes of poor outcome in patients admitted in good grade sah. | 2017 | 28108855 |
| nonsupersymmetric dualities from mirror symmetry. | we study supersymmetry breaking perturbations of the simplest dual pair of (2+1)-dimensional n=2 supersymmetric field theories-the free chiral multiplet and n=2 super qed with a single flavor. we find dual descriptions of a phase diagram containing four distinct massive phases. the equivalence of the intervening critical theories gives rise to several nonsupersymmetric avatars of mirror symmetry: we find dualities relating scalar qed to a free fermion and wilson-fisher theories to both scalar an ... | 2017 | 28106458 |
| implementing a structured reporting initiative using a collaborative multistep approach. | to describe the successful implementation of a structured reporting initiative in a large urban academic radiology department. | 2017 | 28104315 |
| tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing - a case report. | endometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer may be very challenging but is essential for prognostic and therapeutic considerations. | 2017 | 28103826 |
| sustained-release delivery system of a slow hydrogen sulfide donor, gyy 4137, for potential application in glaucoma. | hydrogen sulfide (h2s) targets both underlying factors in glaucoma pathogenesis by reducing elevated intraocular pressure (iop) and providing retinal neuroprotection, whereas the current clinical approaches targets only reducing iop. therefore, h2s could be a potential superior candidate for glaucoma pharmacotherapy. however, h2s could be toxic in a concentration greater than 200 μm and its donors are unstable in water. therefore, this study investigated the preparation and characterization of a ... | 2017 | 28101725 |
| comparison of intubating laryngeal mask airway and fiberoptic bronchoscopy for endotracheal intubation in patients undergoing cervical discectomy. | direct laryngoscopy is hazardous in patients with cervical posterior intervertebral disc prolapse (pivd) as it may worsen the existing cord compression. to achieve smooth intubation, many adjuncts such as fiberoptic bronchoscope (fob), video laryngoscopes, lighted stylets, and intubating laryngeal mask airways (ilmas) are available. however, there is a paucity of literature comparing ilma with fiberoptic intubation in patients with pivd. hence, this study was designed to compare the effectivenes ... | 2017 | 28096586 |
| the future is here, but there is no reason to fear. | nicole fisher, mpp, phd, is the founder and chief executive officer at hhr strategies, a health care and human rights focused advising firm. additionally, she is a senior policy advisor and expert on health economics, technology, and reform, specifically as they affect vulnerable populations. nicole runs a health innovation and policy page at forbes, highlighting and advising companies, ideas, and people that are changing the health landscape. she also is currently pursuing her phd at the univer ... | 2017 | 28096037 |
| pathologic subtypes of ampullary adenocarcinoma: value of ampullary mdct for noninvasive preoperative differentiation. | the purpose of this study was to evaluate the utility of ampullary mdct in the noninvasive, preoperative differentiation of pancreatobiliary and intestinal subtypes of ampullary adenocarcinoma. | 2017 | 28095024 |
| sonographic alteration of substantia nigra is related to parkinsonism-predominant course of x-linked dystonia-parkinsonism. | x-linked recessive dystonia-parkinsonism (xdp, dyt3) is highly prevalent in the philippines and manifests with varying phenotype. we sought to evaluate the significance of transcranial brain sonography as a biomarker for parkinsonism-predominant phenotype. | 2017 | 28094105 |
| involvement of p53 and bcl-2 in sensory cell degeneration in aging rat cochleae. | p53 and bcl-2 (b-cell lymphoma 2) are involved in the process of sensory cell degeneration in aging cochleae. | 2017 | 28093932 |
| therapeutic complement inhibition: a promising approach for treatment of neuroimmunological diseases. | autoimmunity is an important cause of disease both in the central and peripheral nervous systems. aetiologies and clinical manifestations are complex and heterogeneous. inappropriate control of complement activation at inappropriate sites has been recognized as a major determinant in several neurological conditions, including guillain-barré syndrome and neuromyelitis optica. in each case pathogenesis is thought to be associated with generation of autoantibodies which upon binding guide activatio ... | 2017 | 28092989 |
| problem internet use and internet gaming disorder: a survey of health literacy among psychiatrists from australia and new zealand. | research is limited on psychiatrists' opinions on the concepts of internet gaming disorder (igd) and problematic internet use (piu). we aimed to assess health literacy among psychiatrists on igd/piu. | 2017 | 28092969 |
| moments of von mises and fisher distributions and applications. | the von mises and fisher distributions are spherical analogues to the normal distribution on the unit circle and unit sphere, respectively. the computation of their moments, and in particular the second moment, usually involves solving tedious trigonometric integrals. here we present a new method to compute the moments of spherical distributions, based on the divergence theorem. this method allows a clear derivation of the second moments and can be easily generalized to higher dimensions. in par ... | 2017 | 28092958 |
| differences in peripheral blood lymphocytes between brand-name and generic tacrolimus used in stable liver transplant recipients. | in this study, peripheral blood lymphocytes were compared between a brand-name and a generic tacrolimus group in stable liver transplant recipients. | 2017 | 28092916 |
| determination of the edge of criticality in echo state networks through fisher information maximization. | it is a widely accepted fact that the computational capability of recurrent neural networks (rnns) is maximized on the so-called "edge of criticality." once the network operates in this configuration, it performs efficiently on a specific application both in terms of: 1) low prediction error and 2) high short-term memory capacity. since the behavior of recurrent networks is strongly influenced by the particular input signal driving the dynamics, a universal, application-independent method for de ... | 2017 | 28092580 |
| compositional model based fisher vector coding for image classification. | deriving from the gradient vector of a generative model of local features, fisher vector coding (fvc) has been identified as an effective coding method for image classification. most, if not all, fvc implementations employ the gaussian mixture model (gmm) as the generative model for local features. however, the representative power of a gmm can be limited because it essentially assumes that local features can be characterized by a fixed number of feature prototypes, and the number of prototypes ... | 2017 | 28092518 |
| nocturnal enuresis in school-aged children with sickle-cell anemia: any relationship with hyposthenuria? | reports show that children with sickle-cell anemia (sca) have a tendency for nocturnal enuresis when compared with their counterparts with normal hemoglobin. although nocturnal enuresis in sca has been attributed to several factors including tubular and even bladder dysfunction, its relationship with hyposthenuria has been questioned in some studies. | 2017 | 28091440 |
| more fishers and fewer martens due to cumulative effects of forest management and climate change as evidenced from local knowledge. | monitoring of fur-bearing species populations is relatively rare due to their low densities. in addition to catch data, trappers' experience provides information on the ecology and status of the harvested species. fisher (pekania pennanti) and american marten (martes americana) are mustelids that are sensitive to forest management and therefore considered to be ecological indicators of forest health. fisher populations have increased in eastern north america since the early 2000s and this could ... | 2017 | 28882186 |
| white matter changes in microstructure associated with a maladaptive response to stress in rats. | in today's society, every individual is subjected to stressful stimuli with different intensities and duration. this exposure can be a key trigger in several mental illnesses greatly affecting one's quality of life. yet not all subjects respond equally to the same stimulus and some are able to better adapt to them delaying the onset of its negative consequences. the neural specificities of this adaptation can be essential to understand the true dynamics of stress as well as to design new approac ... | 2017 | 28117841 |
| comorbid psychiatric disorders in children and adolescents with nocturnal enuresis. | the present study was conducted with the aim of identifying the frequency of comorbid psychiatricdisorders in children and adolescents with nocturnal enuresis (ne). | 2017 | 28116741 |
| using actigraphy and mhealth systems for an objective analysis of sleep quality on systemic lupus erythematosus patients. | although sleep alterations can be an important factor contributing to the clinical state of systemic lupus erythematosus, there are no studies to adequately assess sleep quality in this type of disease. | 2017 | 28116413 |
| risk of secondary osteoporosis due to lobular cholestasis in non-cirrhotic primary biliary cholangitis. | it remains unclear whether primary biliary cholangitis (pbc) represents a risk factor for secondary osteoporosis. | 2017 | 28114749 |
| improving large-scale image retrieval through robust aggregation of local descriptors. | visual search and image retrieval underpin numerous applications, however the task is still challenging predominantly due to the variability of object appearance and ever increasing size of the databases, often exceeding billions of images. prior art methods rely on aggregation of local scale-invariant descriptors, such as sift, via mechanisms including bag of visual words (bow), vector of locally aggregated descriptors (vlad) and fisher vectors (fv). however, their performance is still short of ... | 2017 | 28114059 |
| fast threshold image segmentation based on 2d fuzzy fisher and random local optimized qpso. | in the paper, a real-time segmentation method that separates the target signal from the navigation image is proposed. in the approaching docking stage, the navigation image is composed of target and non-target signal, which are separately bright spot and space vehicle itself. since the non-target signals is the main part of the navigation image, the traditional entropy-related criterions and ostu-related criterions will bring inadequate segmentation, while the mere 2d fisher criterion will cause ... | 2017 | 28113762 |
| a case of miller fisher syndrome, thromboembolic disease, and angioedema: association or coincidence? | background miller fisher syndrome is characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia, and is considered to be a variant of guillain-barre syndrome. miller fisher syndrome is observed in approximately 1-5% of all guillain-barre cases in western countries. patients with miller fisher syndrome usually have good recovery without residual deficits. venous thromboembolism is a common complication of guillain-barre syndrome and has also been reported in miller fisher syndr ... | 2017 | 28090073 |
| hydrogel spacer distribution within the perirectal space in patients undergoing radiotherapy for prostate cancer: impact of spacer symmetry on rectal dose reduction and the clinical consequences of hydrogel infiltration into the rectal wall. | hydrogel prostate-rectum spacers, biomaterials placed between the prostate and rectum, continue to gain interest as a method to reduce or limit rectal dose during dose escalated prostate cancer radiation therapy. because the spacer is initially injected into the perirectal space as a liquid, the final distribution can vary. the purpose of this study was to evaluate hydrogel spacer (spaceoar system) implantation and distribution from a recent prospective randomized control trial and correlate spa ... | 2017 | 28089528 |
| human disruption of coral reef trophic structure. | the distribution of biomass among trophic levels provides a theoretical basis for understanding energy flow and the hierarchical structure of animal communities. in the absence of energy subsidies [1], bottom-heavy trophic pyramids are expected to predominate, based on energy transfer efficiency [2] and empirical evidence from multiple ecosystems [3]. however, the predicted pyramid of biomass distribution among trophic levels may be disrupted through trophic replacement by alternative organisms ... | 2017 | 28089513 |
| limiting fitness distributions in evolutionary dynamics. | natural selection works on variation in fitness, but how should we measure "variation" to predict the rate of future evolution? fisher's fundamental theorem of natural selection provides the short-run answer: the instantaneous rate of growth of a population's mean fitness is its variance in fitness. this identity captures an important feature of the evolutionary process, but, because it does not specify how the variance itself evolves in time, it cannot be used to predict evolutionary dynamics i ... | 2017 | 28069447 |
| prediction of lymphatic dissemination in endometrioid endometrial cancer: comparison of three risk-stratification models in a single-institution cohort. | to compare the performance characteristics of 3 risk-stratification models, referred to as mayo, helsinki and milwaukee models, in predicting lymphatic dissemination in endometrial cancer. | 2017 | 28069268 |
| differences in types and incidence of neoplasms in wistar han and sprague-dawley rats. | a substantial quantity of data on sprague-dawley (sd) and hannover wistar rats strains have been published concerning their source, diet, and housing conditions, as well as the incidences of nonneoplastic lesions and neoplasms observed in different laboratories. differences between the commonly used rat strains provided by different breeders (i.e., cd (sd) vs. harlan sprague-dawley strain or crl: wi(han) vs. wistar hannover (han)-derived strain, continued breeding by rcc ltd., switzerland, there ... | 2017 | 28068893 |
| patterns of relapse in high-risk neuroblastoma patients treated with and without total body irradiation. | external beam radiation therapy to initial sites of disease may influence relapse patterns in high-risk neuroblastoma. however, the effect of systemic irradiation by use of total body irradiation (tbi) on anatomic patterns of relapse has not previously been investigated. | 2017 | 28068235 |
| association between obesity and perioperative morbidity in open versus laparoscopic sacrocolpopexy. | the aim of this study was to compare differences in 30-day perioperative morbidity and mortality for women undergoing open sacrocolpopexy (oscp) versus laparoscopic sacrocolpopexy (lscp) across all body mass index (bmi) groups and between patients of ideal versus elevated bmi (includes overweight, obese, and morbidly obese). | 2017 | 28067749 |
| levator ani muscle defects in patients with surgical failure. | the objective of the study was to use a well-described system of measuring levator ani (la) muscle defects from magnetic resonance images to evaluate whether major defects are correlated to an increased risk of surgical failure. | 2017 | 28067748 |
| schwann cells are activated by atp released from neurons in an in vitro cellular model of miller fisher syndrome. | the neuromuscular junction is exposed to different types of insult, including mechanical trauma, toxins and autoimmune antibodies and, accordingly, has retained through evolution a remarkable ability to regenerate. regeneration is driven by multiple signals that are exchanged among the cellular components of the junction. these signals are largely unknown. miller fisher syndrome is a variant of guillain-barré syndrome caused by autoimmune antibodies specific for epitopes of peripheral axon termi ... | 2017 | 28067631 |
| the effects of vacuum fluctuations on teleportation of quantum fisher information. | the teleported quantum fisher information of the phase parameter of atomic state is studied in consideration of vacuum fluctuations. our results show that the teleported information is determined by the wavelength of the atoms as well as the distance of teleportation. when the wavelength of the atoms is much smaller than the teleportation distance, the teleported information decays with time and the decay rates are determined by the spontaneous emission rate of the atoms. however, when the wavel ... | 2017 | 28067291 |
| venous thromboembolism in pediatric trauma patients: ten-year experience and long-term follow-up in a tertiary care center. | pediatric trauma patients are at high risk for development of venous thromboembolism (vte). our objective is to describe incidence, risk factors, and timing of development of vte, anticoagulation complications, and long-term vte outcomes in a critically injured pediatric population. | 2017 | 28067012 |
| [influence of postcode on paediatric admissions in seville]. | the postcode (where the home is situated) is an indicator of socioeconomic status and is associated with morbidity, mortality, and the use of health services. the aim of this study was to analyse its effects on paediatric admissions and to determine the rates of the most common causes of paediatric admissions in seville. | 2017 | 28063821 |
| incidence and risk factors for post-ercp pancreatitis in chronic pancreatitis. | almost all studies on post-ercp pancreatitis (pep) have mainly involved patients with biliary diseases rather than chronic pancreatitis (cp), and the concept that cp seems to be a protective factor associated with pep has not been studied in detail. the aim of this study was to determine the incidence of pep in patients with cp at different clinical stages and to identify the predictive and protective factors of pep in a large cohort. | 2017 | 28062312 |
| phospho-akt overexpression is prognostic and can be used to tailor the synergistic interaction of akt inhibitors with gemcitabine in pancreatic cancer. | there is increasing evidence of a constitutive activation of akt in pancreatic ductal adenocarcinoma (pdac), associated with poor prognosis and chemoresistance. therefore, we evaluated the expression of phospho-akt in pdac tissues and cells, and investigated molecular mechanisms influencing the therapeutic potential of akt inhibition in combination with gemcitabine. | 2017 | 28061880 |
| a novel method to promote physical activity among older adults in residential care: an exploratory field study on implicit social norms. | physical activity (pa) levels of older adults living in a care setting are known to be very low. this is a significant health(care) problem, as regular pa has many health benefits also at advanced age. research on automatic processes underlying pa behaviour in physically inactive older adults is yet non-existing. since people are unconsciously influenced by people around them (i.e. by 'social norms') automatic processes could be used to promote pa. we developed an explorative intervention method ... | 2017 | 28061756 |
| effects of circadian rhythms and treatment times on the response of radiotherapy for painful bone metastases. | previous studies have observed how the time of radiotherapy delivery can impact toxicities and outcomes. the goal of this study was to determine whether treatment time influenced radiotherapy response for bone metastases. | 2017 | 28061531 |
| morphological distribution of the anterior inferior iliac spine in patients with and without hip impingement: reliability, validity, and relationship to the intraoperative assessment. | subspinous impingement of the anterior inferior iliac spine (aiis) on the femoral head-neck junction is increasingly recognized as a source of hip impingement. a classification system of aiis morphology has previously been proposed that correlates with reduced hip motion and may predispose patients to subspinous hip impingement. | 2017 | 28060533 |
| catechol-o-methyltransferase genotypes and parenting influence on long-term executive functioning after moderate to severe early childhood traumatic brain injury: an exploratory study. | to examine catechol-o-methyltransferase (comt) rs4680 genotypes as moderators of the effects of parenting style on postinjury changes in parent behavior ratings of executive dysfunction following moderate to severe early childhood traumatic brain injury. | 2017 | 28060209 |
| sustainable theory of a logistic model - fisher information approach. | information theory provides a useful tool to understand the evolution of complex nonlinear systems and their sustainability. in particular, fisher information has been evoked as a useful measure of sustainability and the variability of dynamical systems including self-organising systems. by utilising fisher information, we investigate the sustainability of the logistic model for different perturbations in the positive and/or negative feedback. specifically, we consider different oscillatory modu ... | 2017 | 28057457 |
| retention prediction of low molecular weight anions in ion chromatography based on quantitative structure-retention relationships applied to the linear solvent strength model. | quantitative structure-retention relationships (qsrrs) represent a popular technique to predict the retention times of analytes, based on molecular descriptors encoding the chemical structures of the analytes. the linear solvent strength (lss) model relating the retention factor, k to the eluent concentration (log k=a-blog [eluent]), is a well-known and accurate retention model in ion chromatography (ic). in this work, qsrrs for inorganic and small organic anions were used to predict the regress ... | 2017 | 28057331 |
| marine reserve targets to sustain and rebuild unregulated fisheries. | overfishing threatens the sustainability of coastal marine biodiversity, especially in tropical developing countries. to counter this problem, about 200 governments worldwide have committed to protecting 10%-20% of national coastal marine areas. however, associated impacts on fisheries productivity are unclear and could weaken the food security of hundreds of millions of people who depend on diverse and largely unregulated fishing activities. here, we present a systematic theoretic analysis of t ... | 2017 | 28056064 |
| a stable finite-difference scheme for population growth and diffusion on a map. | we describe a general godunov-type splitting for numerical simulations of the fisher-kolmogorov-petrovski-piskunov growth and diffusion equation on a world map with neumann boundary conditions. the procedure is semi-implicit, hence quite stable. our principal application for this solver is modeling human population dispersal over geographical maps with changing paleovegetation and paleoclimate in the late pleistocene. as a proxy for carrying capacity we use net primary productivity (npp) to pred ... | 2017 | 28085882 |
| two-incision laparoscopic cholecystectomy in children. | to evaluate two-incision laparoscopic cholecystectomy (2i-lc) in children, and compare outcomes with four-port laparoscopic cholecystectomy (4p-lc). | 2017 | 28085557 |
| study of behavioural disorders in children with primary enuresis. | enuresis results in behavioural disorder in children. this study investigated the behavioural disorders in children possessing primary enuresis. | 2017 | 28084151 |
| error analysis in newborn screening: can quotients support the absolute values? | newborn screening is performed using modern tandem mass spectrometry, which can simultaneously detect a variety of analytes, including several amino acids and fatty acids. tandem mass spectrometry measures the diagnostic parameters as absolute concentrations and produces fragments which are used as markers of specific substances. several prominent quotients can also be derived, which are quotients of two absolute measured concentrations. in this study, we determined the precision of both the abs ... | 2017 | 28083661 |
| super normal vector for human activity recognition with depth cameras. | the advent of cost-effectiveness and easy-operation depth cameras has facilitated a variety of visual recognition tasks including human activity recognition. this paper presents a novel framework for recognizing human activities from video sequences captured by depth cameras. we extend the surface normal to polynormal by assembling local neighboring hypersurface normals from a depth sequence to jointly characterize local motion and shape information. we then propose a general scheme of super nor ... | 2017 | 28113701 |
| semisupervised feature selection based on relevance and redundancy criteria. | feature selection aims to gain relevant features for improved classification performance and remove redundant features for reduced computational cost. how to balance these two factors is a problem especially when the categorical labels are costly to obtain. in this paper, we address this problem using semisupervised learning method and propose a max-relevance and min-redundancy criterion based on pearson's correlation (rrpc) coefficient. this new method uses the incremental search technique to s ... | 2017 | 28113443 |
| carotenoid profiling of the leaves of selected african eggplant accessions subjected to drought stress. | african eggplants (solanum aethiopicum and s. macrocarpon) are among the most economically important and valuable vegetable and fruit crops. they are a major source of biologically active nutritional substances and metabolites which are essential for plant growth, development, stress adaptation and defense. among these metabolites are the carotenoids which act as accessory pigments for photosynthesis and precursor to plant hormones. though african eggplants are known to be resistant to various a ... | 2017 | 28070322 |
| higher rates of sex evolve during adaptation to more complex environments. | a leading hypothesis for the evolutionary maintenance of sexual reproduction proposes that sex is advantageous because it facilitates adaptation. changes in the environment stimulate adaptation but not all changes are equivalent; a change may occur along one or multiple environmental dimensions. in two evolution experiments with the facultatively sexual rotifer brachionus calyciflorus, we test how environmental complexity affects the evolution of sex by adapting replicate populations to various ... | 2017 | 28053226 |
| reasons for chemotherapy refusal or acceptance in older adults with cancer. | the majority of americans diagnosed as having cancer are older than 65 years. they are, however, less likely than younger patients to receive chemotherapy. our study aimed to better understand the specific reasons for acceptance or refusal of chemotherapy in older adults with cancer. | 2017 | 28052175 |
| refining prognosis for intracerebral hemorrhage by early reassessment. | prognostic assessments, which are crucial for decision-making in critical illnesses, have shown unsatisfactory reliability. we compared the accuracy of a widely used prognostic score against a model derived from clinical data obtained 5 days after admission for patients with intracerebral hemorrhage (ich), a condition for which prognostication has proven notoriously challenging and prone to bias. | 2017 | 28049196 |
| efficacy and safety of duloxetine in chinese patients with chronic pain due to osteoarthritis: a randomized, double-blind, placebo-controlled study. | we assessed the efficacy and safety of duloxetine (60 mg, once daily), compared with placebo, during a 13-week treatment period in chinese patients with chronic pain due to osteoarthritis (oa). | 2017 | 28043937 |
| similar efficacies of endoscopic ultrasound gallbladder drainage with a lumen-apposing metal stent versus percutaneous transhepatic gallbladder drainage for acute cholecystitis. | acute cholecystitis in patients who are not candidates for surgery is often managed with percutaneous transhepatic gallbladder drainage (pt-gbd). endoscopic ultrasound-guided gallbladder drainage (eus-gbd) with a lumen-apposing metal stent (lams) is an effective alternative to pt-gbd. we compared the technical success of eus-gbd versus pt-gbd, and patient outcomes, numbers of adverse events (aes), length of hospital stay, pain scores, and repeat interventions. | 2017 | 28043931 |
| serum uric acid level in relation to severity of the disease and mortality of critically ill patients. | this study was conducted to evaluate the validity of serum uric acid (ua) in prediction of mortality among patients in the emergency department. | 2017 | 28042216 |
| an alternative derivation of the stationary distribution of the multivariate neutral wright-fisher model for low mutation rates with a view to mutation rate estimation from site frequency data. | recently, burden and tang (2016) provided an analytical expression for the stationary distribution of the multivariate neutral wright-fisher model with low mutation rates. in this paper we present a simple, alternative derivation that illustrates the approximation. our proof is based on the discrete multivariate boundary mutation model which has three key ingredients. first, the decoupled moran model is used to describe genetic drift. second, low mutation rates are assumed by limiting mutations ... | 2017 | 28041892 |
| takotsubo cardiomyopathy associated with miller-fisher syndrome. | 51-year-old female who presented with progressive paresthesia, numbness of the lower extremities, double vision, and trouble walking. physical exam was remarkable for areflexia, and ptosis. her initial ekg showed nonspecific st segment changes and her troponin t was elevated to 0.41ng/ml which peaked at 0.66ng/ml. echocardiogram showed a depressed left ventricular ejection fraction to 35% with severely hypokinetic anterior wall and left ventricular apex was severely hypokinetic. emg nerve conduc ... | 2017 | 28040387 |
| high frequency of programmed death-ligand 1 expression in emphysematous bullae-associated lung adenocarcinomas. | emphysematous bullae (eb) are known to be associated with a high incidence of lung cancer; however, the reason for this has yet to be elucidated. the objective of the present study was to clarify the prevalence of programmed death-ligand-1 (pd-l1) expression in eb-associated lung adenocarcinomas. | 2017 | 28038981 |
| failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta. | failure of physiologic transformation of spiral arteries has been reported in preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact or ruptured membranes. spiral arteries with failure of physiologic transformation are prone to develop atherosclerotic-like lesions of atherosis. there are striking parallels between preeclampsia and atherosclerotic disease, and between lesions of atherosis and atherosclerosis. endothelial activation, identified by intercellu ... | 2017 | 28034657 |
| sample size determination for the fluctuation experiment. | the luria-delbrück fluctuation experiment protocol is increasingly employed to determine microbial mutation rates in the laboratory. an important question raised at the planning stage is "how many cultures are needed?" for over 70 years sample sizes have been determined either by intuition or by following published examples where sample sizes were chosen intuitively. this paper proposes a practical method for determining the sample size. the proposed method relies on existing algorithms for comp ... | 2017 | 28033535 |
| vitamin d status among long-term survivors of testicular cancer. | a correlation between disturbances in hormone levels and the onset of metabolic disorders has been reported in long-term survivors of testicular cancer (tc).we evaluated serum vitamin d levels and other biological parameters in a consecutive series of 61 long-term (≥3 years) unilateral tc survivors with a median a follow-up of 4 years and in a cohort of healthy males. deficient vitamin d levels were observed in 10 (17%) of the 58 long-term unilateral tc survivors but were not reported in healthy ... | 2017 | 28030821 |
| healthy exercise habits are associated with lower risk of burnout and higher quality of life among u.s. medical students. | although burnout and low quality of life (qol) are common among medical students, little remains known about personal fitness habits of medical students that may promote well-being. | 2017 | 28030419 |
| clinical value of neutrophil to lymphocyte and platelet to lymphocyte ratio after aneurysmal subarachnoid hemorrhage. | inflammation and thrombosis are associated with the pathogenesis of aneurysmal subarachnoid hemorrhage (asah) and neutrophil to lymphocyte ratio (nlr) and platelet to lymphocyte ratio (plr) are emerging as novel inflammatory markers in stroke. we aimed to identify the association of nlr and plr with delayed cerebral ischemia (dci) and 3-month outcome after asah. | 2017 | 28028791 |
| comprehensive two-dimensional gas chromatographic profiling and chemometric interpretation of the volatile profiles of sweat in knit fabrics. | human axillary sweat is a poorly explored biofluid within the context of metabolomics when compared to other fluids such as blood and urine. in this paper, we explore the volatile organic compounds emitted from two different types of fabric samples (cotton and polyester) which had been worn repeatedly during exercise by participants. headspace solid-phase microextraction (spme) and comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (gc×gc-tofms) were employed to pr ... | 2017 | 28028595 |
| impact of industry collaboration on randomised controlled trials in oncology. | industry funders can simply provide money or collaborate in trial design, analysis or reporting of clinical trials. our aim was to assess the impact of industry collaboration on trial methodology and results of randomised controlled trials (rct). | 2017 | 28027518 |
| the prevalence and risk factors associated with osteoradionecrosis of the jaw in oral and oropharyngeal cancer patients treated with intensity-modulated radiation therapy (imrt): the memorial sloan kettering cancer center experience. | to determine the prevalence and correlation of various risk factors [radiation dose, periodontal status, alcohol and smoking] to the development of osteoradionecrosis (orn). | 2017 | 28024723 |
| survey evaluating the practice of children's hospitals having pharmacist collaborative drug therapy management protocols. | objectives: the purpose of this study is to determine how frequently children's hospitals in the united states are using pharmacist-physician collaborative drug therapy management (cdtm), and to characterize their use in this population. methods: a phone survey was created to collect data regarding the use of pharmacist-physician cdtm at children's hospitals. children's hospitals were called between february 2014 and april 2014. data were collected from either a clinical pharmacist or pharmacy d ... | 2017 | 28018151 |
| spheno-orbital meningiomas: a 16-year surgical experience. | to examine the efficacy of spheno-orbital meningioma (som) resection aimed at symptomatic improvement, rather than gross total resection, followed by radiation therapy for recurrence. | 2017 | 28017748 |
| perspectives of patients and family members regarding psychological support using intensive care diaries: an exploratory mixed methods study. | diaries summarizing intensive care are routine practice in some countries, although evidence to support diary use is limited. the purpose of this study was to identify whether distress post-intensive care influences patients' and relatives' choice as to whether they would like to receive a diary and what information delivery method is preferred. | 2017 | 28011420 |
| common femoral artery access on youtube: what practices are being shown and who is delivering the message? | novice learners are increasingly turning to youtube as a learning resource for surgical procedures. one example of such a procedure is common femoral artery puncture and sheath placement. practitioners in several specialties perform this procedure to access the arterial system for angiography and intervention. we set forth to compare the techniques demonstrated on youtube by the various specialists, as well as compare each specialty׳s prevalence on this website. | 2017 | 28011261 |
| urine culture guided antibiotic interventions: a pharmacist driven antimicrobial stewardship effort in the ed. | antibiotics are overprescribed for abnormal urine tests including asymptomatic bacteriuria (ab), contributing to rising antimicrobial resistance rates. pharmacists reviewed urine cultures daily from emergency department (ed) encounters to assess antibiotic appropriateness. we studied antibiotic prescribing practices and assessed compliance to national guidelines, correlations with urine analysis (ua) components, and opportunities for antimicrobial stewardship in the ed. | 2017 | 28010959 |
| simultaneous ability and difficulty estimation via the linear discriminant function. | in this paper, parameter estimation of the dichotomous rasch model (rasch, 1960) using the linear discriminant function (fisher, 1936) is presented. this is accomplished by considering the scored item responses to be distinct groups and using a design matrix that is identical to one used in logistic regression for joint maximum likelihood estimation. the real dataset that was examined was the fraction subtraction dataset from tatsuoka (1984). through simulation parameter estimation accuracy usin ... | 2017 | 28009590 |
| detecting spatial regimes in ecosystems. | research on early warning indicators has generally focused on assessing temporal transitions with limited application of these methods to detecting spatial regimes. traditional spatial boundary detection procedures that result in ecoregion maps are typically based on ecological potential (i.e. potential vegetation), and often fail to account for ongoing changes due to stressors such as land use change and climate change and their effects on plant and animal communities. we use fisher information ... | 2017 | 28000431 |
| mixed-valence nickel bis(azamacrocycle) compounds with ghost-leg-type sheets. | the fabrication of so-called ghost-leg sheets and their electronic properties is reported. this unique sheet structure is composed of one-dimensional mixed-valence nickel chains, which are linked with one another by bis(azamacrocycle) ligands. they are also topologically unique ni(ii) /ni(iii) mixed-valence complexes, as confirmed by x-ray and optical measurements. moreover, their magnetic susceptibilities indicated two-dimensional antiferromagnetic behavior following the fisher 1d chain model w ... | 2017 | 28000324 |
| topical oral cavity chemoprophylaxis using isotretinoin rinse: a 15-year experience. | to determine the utility of isotretinoin oral rinses as a method of chemoprevention for recurrent oral cavity squamous cell carcinoma (scc), carcinoma in situ, and dysplasia. | 2017 | 28000225 |
| what is important for confirming negative margins when resecting mandibular ameloblastomas? | the purpose of this study was to assess the utility of intraoperative radiographs and frozen sections in achieving negative margins and preventing recurrence of mandibular ameloblastomas. | 2017 | 27998738 |
| the relationship between polyethylene wear and periprosthetic osteolysis in total hip arthroplasty at 12 years in a randomized controlled trial cohort. | polyethylene acetabular components are common in hip arthroplasty. highly cross-linked polyethylene (hxlpe) has lower wear than ultra-high molecular weight polyethylene (uhmwpe). evidence suggests that wear particles induce inflammation causing periprosthetic osteolysis contributing to implant loosening with wear rates of 0.05 mm/y were considered safe. we aimed to compare incidence and volume of periacetabular osteolysis between hxlpe and uhmwpe using computed tomography. | 2017 | 27998657 |
| basalit trial: double-blind placebo-controlled allergen immunotherapy with rbet v 1-fv in birch-related soya allergy. | conflicting results exist on the effect of allergen immunotherapy (ait) on pollen-related food allergy. we aimed to investigate the efficacy of one-year ait with the folding variant (fv) of recombinant (r) bet v 1 on birch-related soya allergy. | 2017 | 27998002 |
| existence of traveling waves for the generalized f-kpp equation. | variation in genotypes may be responsible for differences in dispersal rates, directional biases, and growth rates of individuals. these traits may favor certain genotypes and enhance their spatiotemporal spreading into areas occupied by the less advantageous genotypes. we study how these factors influence the speed of spreading in the case of two competing genotypes under the assumption that spatial variation of the total population is small compared to the spatial variation of the frequencies ... | 2017 | 28008475 |
| flow diversion in ruptured intracranial aneurysms: a meta-analysis. | flow diversion is now an established technique to treat unruptured intracranial aneurysms not readily amenable to endovascular coil embolization or open microsurgical occlusion. the role of flow-diverting devices in treating ruptured aneurysms is less clear. | 2017 | 28007770 |
| everolimus tdm using thermo fisher qms immunoassay on indiko, beckman dxc, au680, and au5800 analyzers. | everolimus (evr), a mtor inhibitor immunosuppressant approved for renal, liver and cardiac transplants. this study established the appropriate tdm performances of the thermo scientific qms evr assay by using the beckman dxc, followed by comparison to the thermo scientific indiko and a previously published lc-ms/ms assay, and beckman au680 and au5800 analyzers. | 2017 | 27988326 |
| association between axl, hippo transducers, and survival outcomes in male breast cancer. | male breast cancer (mbc) is an uncommon malignancy. we have previously reported that the expression of the hippo transducers taz/yap and their target ctgf was associated with inferior survival in mbc patients. preclinical evidence demonstrated that axl is a transcriptional target of taz/yap. thus, we herein assessed axl expression to further investigate the significance of active taz/yap-driven transcription in mbc. for this study, 255 mbc samples represented in tissue microarrays were screened ... | 2017 | 27987320 |
| sex differences in mortality and morbidity following repair of intact abdominal aortic aneurysms. | medicare studies have shown increased perioperative mortality in women compared with men following endovascular and open abdominal aortic aneurysm (aaa) repair. however, a recent regional study of high-volume centers, adjusting for anatomy but limited in sample size, did not show sex to be predictive of worse outcomes. this study aimed to evaluate sex differences after intact aaa repair in a national clinical registry. | 2017 | 27986477 |
| measuring changes in the optic nerve sheath diameter in patients with idiopathic normal-pressure hydrocephalus: a useful diagnostic supplement to spinal tap tests. | cerebrospinal fluid (csf) removal improves clinical symptoms of many patients with idiopathic normal-pressure hydrocephalus (inph). the aim of this study was to investigate the correlation of changes in the optic nerve sheath diameter (onsd) with patient responses to csf removal. | 2017 | 27981690 |