Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| cost-utility analysis of focal high-intensity focussed ultrasound vs active surveillance for low- to intermediate-risk prostate cancer using a markov multi-state model. | to estimate the relative cost-effectiveness of focal high-intensity focussed ultrasound (f-hifu) compared to active surveillance (as) in patients with low- to intermediate-risk prostate cancer, in france. | 2019 | 31298775 |
| dynamics of puumala hantavirus outbreak in black sea region, turkey. | some of the hantavirus species in euro-asia cause haemorrhagic fever with renal syndrome (hfrs) in humans. the first documented human hantavirus infection in turkey was diagnosed in 2009. this report describes the dynamics of the first hantavirus outbreak that emerged in humans in the western black sea region of turkey. | 2019 | 31293096 |
| authors' correction for euro surveill. 2012;17(22). | 2019 | 31290389 | |
| the economic burden of adult attention deficit hyperactivity disorder: a sibling comparison cost analysis. | attention deficit hyperactivity disorder (adhd) is a lifespan disorder associated with considerable economic cost. while the economic burden of adhd has been widely estimated, there is considerable variation in reported costs between studies, which typically focus on health outcomes only, lack adequate control and fail to correct for the influence of genetic and shared environmental factors. the aim of this study is to overcome these limitations to reach a fuller understanding of the economic bu ... | 2019 | 31288209 |
| denitrification and anammox: understanding nitrogen loss from yangtze estuary to the east china sea (ecs). | the yangtze river, which is the largest in euro-asian, receives tremendous anthropogenic nitrogen input and is typically characterized by severe eutrophication and hypoxia. two major processes, denitrification and anaerobic ammonium oxidation (anammox), play vital roles for removing nitrogen global in nitrogen cycling. in the current study, sediment samples were collected from both latitudinal and longitudinal transects along the coastal yangtze river and the east china sea (ecs). we investigate ... | 2019 | 31284208 |
| [the challenges of surgical tourism in the field of aesthetic surgery]. | surgical tourism is a growing phenomenon, causing a surge demand for the management of its complications. in this study, we aimed to evaluate complications that occur after cosmetic breast surgery abroad; and their costs for the public health system. | 2019 | 31280881 |
| the impact of low to high waste cooking oil-based biodiesel blends on toxic organic pollutant emissions from heavy-duty diesel engines. | as yet, the effect of biodiesels on the emissions of polycyclic aromatic hydrocarbons (pahs) and polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdd/fs) from heavy-duty diesel engines (hddes) has only been studied using limited fuel blend ratios. to clarify the influence of using higher fractions of biodiesel on the emissions of toxic organic pollutants from diesel engines, in this research, the emissions of pm, pahs, and persistent organic pollutants (pops) from euro iv and euro iii hddes ... | 2019 | 31279123 |
| offensive transitions in high-performance football: differences between uefa euro 2008 and uefa euro 2016. | coaches, footballers and researchers agree that offensive transitions are one of the most important moments in football today. in a sport where defense over attack dominates, with low scores on the scoreboard, the importance of these actions from the offensive point of view becomes very important. despite this, scientific literature is still very limited on this topic. therefore, the objectives set out in the present investigation have been two: first, by means of a proportion analysis and the a ... | 2019 | 31275190 |
| evaluating the feasibility of a software prototype supporting the management of multimorbid seniors: mixed methods study in general practices. | longitudinal, patient-centered care represents a challenge for general practices. decision support and reminder systems can offer targeted support. | 2019 | 31274115 |
| [assistance program in quitting tobacco use in navarra. 25 years on stage]. | in navarre, the smoking cessation program (paf) was launched in 1994, result of the collaboration between public health and primary care. in 2001 it was integrated into the tobacco regional action plan, together with the other two lines of action: prevention of smoking initiation and promotion of smoke-free spaces. paf includes two levels of intervention, a basic and an intensive one, with programmed educational support, individual and group. medications for smoking cessation have been intermitt ... | 2019 | 31273187 |
| longer treatment duration and history of osteoarticular symptoms predispose to tyrosine kinase inhibitor withdrawal syndrome. | the effectiveness of tyrosine kinase inhibitors (tkis) has made it possible to consider treatment discontinuation in chronic myeloid leukaemia (cml) patients that achieve an excellent response. however, a few of the patients included in the europe stop tyrosine kinase inhibitors (euro-ski) trial reported musculoskeletal pain shortly after stopping tkis, considered as a withdrawal syndrome (ws). to identify factors that may predispose to tki ws, we analysed the pharmacovigilance declarations for ... | 2019 | 31271217 |
| the economic impact of biosimilars in oncology and hematology: the case of trastuzumab and rituximab. | biosimilar agents are biologic products that have no clinically meaningful differences in terms of quality, efficacy, safety and immunogenicity compared to an already approved reference biological product, with the potential to reduce the costs of biologics. considering the increasing numbers of oncology biosimilars, it is important to calculate the economic impact of biosimilars in oncology and hemathology, considering trastuzumab and rituximab as examples, with their greatest budgetary impact ... | 2019 | 31262930 |
| perinatal health monitoring through a european lens: eight lessons from the euro-peristat report on 2015 births. | 2019 | 31260601 | |
| the 10th euro-guch/achd meeting. | 2019 | 31259375 | |
| national burden of the pharmaceutical cost of wet compresses and its cost predictors: nationwide cross-sectional study in japan. | although a high number of wet compresses are prescribed daily in medical institutions in japan, our understanding of the national burden of the cost of wet compresses and the details regarding their prescription is far from complete. we investigated the national burden of the annual pharmaceutical cost of wet compresses prescribed in japan and estimated the predictors of this cost using nationwide health insurance claims data. | 2019 | 31256264 |
| cost effectiveness of interval cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in stage iii ovarian cancer on the basis of a randomized phase iii trial. | in the randomized open-label phase iii ovhipec trial, the addition of hyperthermic intraperitoneal chemotherapy (hipec) to interval cytoreductive surgery (crs) improved recurrence-free and overall survival in patients with stage iii ovarian cancer. we studied the cost effectiveness of the addition of hipec to interval crs in patients with ovarian cancer. | 2019 | 31251694 |
| infectivity and stability of hepatitis c virus in different perfusion solutions. | owing to organ shortage, transplantation of organs from hcv (hepatitis c virus) viremic donors into hcv negative individuals is getting more and more accepted. however, transmission of hcv to the host is nearly universal. until now it is unknown if preservation solutions (ps) might alter infectivity and stability of hcv in the transplant setting. therefore, seven different preservation solutions (ps) with variable composition were tested in vitro for their direct anti- and proviral effects on hc ... | 2019 | 31246353 |
| cost-effectiveness analysis of baricitinib versus adalimumab for the treatment of moderate-to-severe rheumatoid arthritis in spain. | background: baricitinib is an oral janus kinase inhibitor for the treatment of rheumatoid arthritis (ra) and is approved in europe for use in adults with moderately-to-severely active ra and an inadequate response or intolerance to conventional synthetic disease-modifying antirheumatic drug (csdmard) therapy. to date, no economic evaluations have assessed the cost-effectiveness of baricitinib in the spanish setting. objectives: to evaluate the cost-effectiveness of baricitinib versus adalimumab ... | 2019 | 31239736 |
| prospective randomized comparison of fractional flow reserve versus optical coherence tomography to guide revascularization of intermediate coronary stenoses: one-month results. | background fractional flow reserve (ffr) and optical coherence tomography (oct) may help both in assessment and in percutaneous coronary intervention optimization of angiographically intermediate coronary lesions. we designed a prospective trial comparing the clinical and economic outcomes associated with ffr or oct in angiographically intermediate coronary lesions. methods and results three hundred fifty patients with angiographically intermediate coronary lesions (n=446) were randomized to ffr ... | 2019 | 31331219 |
| incidence and costs of hip fractures in elderly italian population: first regional-based assessment. | we analyzed for the first-time hospitalizations and costs for hip fractures in the elderly italian population at the regional level from 2007 to 2014. the number of fractures and the overall costs increased, mainly due to people aged > 85 in all the italian regions, although at different rates. | 2019 | 31342284 |
| authors' correction for euro surveill. 2019;24(27). | 2019 | 31339097 | |
| chronically ill patients' preferences for a financial incentive in a lifestyle intervention. results of a discrete choice experiment. | the preferences of diabetes type 2 patients and cardiovascular disease patients for a financial incentive added to a specified combined lifestyle intervention were investigated. | 2019 | 31344135 |
| joint banknote recognition and counterfeit detection using explainable artificial intelligence. | we investigated machine learning-based joint banknote recognition and counterfeit detection method. unlike existing methods, since the proposed method simultaneously recognize banknote type and detect counterfeit detection, it is significantly faster than existing serial banknote recognition and counterfeit detection methods. furthermore, we propose an explainable artificial intelligence method for visualizing regions that contributed to the recognition and detection. using the visualization, it ... | 2019 | 31430971 |
| gene expression and immunohistochemical analyses identify sox2 as major risk factor for overall survival and relapse in ewing sarcoma patients. | up to 30-40% of ewing sarcoma (ews) patients with non-metastatic disease develop local or metastatic relapse within a time span of 2-10 years. this is in part caused by the absence of prognostic biomarkers that can identify high-risk patients and thus assign them to risk-adapted monitoring and treatment regimens. since cancer stemness has been associated with tumour relapse and poor patient outcomes, we investigated in the current study the prognostic potential sox2 (sex determining region y box ... | 2019 | 31427232 |
| [compression therapy in patients with leg ulcers - which costs do really occur?] | patients with leg ulcers often have severe edema of the lower extremities, which should be treated as part of a successful wound treatment. today in germany the necessary compression therapies are often performed with very error-prone and time-consuming short-stretch bandages only. multicomponent systems, adaptive compression bandages and leg ulcer stocking systems are newer, much less error-prone treatment options. in addition to the often lacking knowledge, the fears of high costs are also men ... | 2019 | 31416099 |
| burden of diabetes mellitus in patients with acromegaly treated with second-line pharmacotherapy in spain. | to evaluate the burden of diabetes mellitus (dm) in adult patients with acromegaly treated with second-line pharmacotherapy, from the perspective of the spanish national health system (nhs). | 2019 | 31413609 |
| clinical and economic burden of head and neck cancer: a nationwide retrospective cohort study from france. | to evaluate the clinical and economic burden of head and neck squamous cell carcinoma (hnscc) in france. | 2019 | 31413607 |
| studying human exposure to vehicular emissions using computational fluid dynamics and an urban mobility simulator: the effect of sidewalk residence time, vehicular technologies and a traffic-calming device. | a computational system consisting of an urban mobility simulator, validated fluid dynamics and an integral exposure model, is proposed to obtain cyclist and pedestrian exposure to pmx and nox. pedestrian activities in the urban anthroposphere include walking and running. the computational experiments take place in a computer-generated urban canyon, subject to emissions from diesel and gasoline euro 5 and euro 6 vehicular technologies, in continuous and stop-and-go traffic scenarios, and three wi ... | 2019 | 31412475 |
| lovastatin in lactone and hydroxy acid forms and citrinin in red yeast rice powders analyzed by hptlc-uv/fld. | for the analysis of pigment-rich red yeast rice products, a fast quantitative high-performance thin-layer chromatography (hptlc) method was newly developed and validated. the active ingredient lovastatin, present in lactone (ll) and hydroxy acid forms (lh), as well as the mycotoxin citrinin were analyzed in 19 red yeast rice products, including powders, dietary supplements, and chinese proprietary medicines (xuezhikang and zhibituo). the hptlc method including sample preparation allows a high th ... | 2019 | 31410535 |
| diesel engine emissions: are they no longer tolerable? | emissions from diesel engines contain several hundred chemical compounds, which are emitted partly as gas and partly as particles. the composition of diesel exhaust and its concentrations in air has changed significantly over time, to the extent that now there is a distinction between "traditional" and "new technology" diesel emissions. new technology diesel engines comply with emissions from euro 3 vehicles and higher. starting with euro 5, a significant further reduction of particle emissions ... | 2019 | 31410529 |
| perception of illness among patients with heart failure is related to their general health independently of their mood and functional capacity. | to explore the relationship between illness perceptions and self-reported general health of patients with chronic heart disease, using some core elements from the common sense model. | 2019 | 31420775 |
| cost-effectiveness of a high-intensity versus a low-intensity smoking cessation intervention in a dental setting: long-term follow-up. | the aim of this study was to conduct a cost-effectiveness analysis (cea) of a high-intensity and a low-intensity smoking cessation treatment programme (hit and lit) using long-term follow-up effectiveness data and to validate the cost-effectiveness results based on short-term follow-up. | 2019 | 31420398 |
| trends in governmental expenditure on vaccination programmes in the netherlands, a historical analysis. | health economic evaluations are often required before implementing a vaccination programme. such evaluations rarely consider the historical context of a vaccination programme. we review the financial history of vaccination programmes in the netherlands, and compare these to demographic and macroeconomic developments as well as avoided mortality burden. | 2019 | 31420172 |
| low-dose in situ perfusion with euro-collins solution is effective for the procurement of marginal kidney grafts from donation after circulatory death donors. | we have adopted a modified method to resuscitate kidneys from donation after circulatory death (dcd) donors with the use of euro-collins (ec) solution instead of university of wisconsin solution. this study aimed to evaluate kidney transplantation (ktx) outcomes of dcd procured with low-dose in situ perfusion using ec solution. | 2019 | 31395361 |
| recombinant zoster vaccine significantly reduces the impact on quality of life caused by herpes zoster in adult autologous hematopoietic stem cell transplant recipients: a randomized placebo-controlled trial (zoe-hsct). | herpes zoster (hz) can have a substantial impact on quality of life (qol). the vaccine efficacy (ve) of a recombinant zoster vaccine (rzv) was 68.2% (95% confidence interval [ci], 55.6% to 77.5%) in a phase 3 study in adult autologous hematopoietic stem cell transplant (hsct) recipients (nct01610414). herein, we report the impact of rzv on patients' qol. autologous hsct recipients were randomized 1:1 to receive 2 doses of rzv or placebo, given 1 to 2 months apart. qol was measured by the short f ... | 2019 | 31394276 |
| evaluation of data availability on population health indicators at the regional level across the european union. | the ability to measure regional health inequalities across europe and to build adequate population health indices depends significantly on the availability of reliable and comparable data at the regional level. within the scope of the eu-funded project euro-healthy, a population health index (phi) was built. this model aggregates 39 indicators considered relevant by experts and stakeholders to evaluate and monitor population health on the regional level within the european union (269 regions). t ... | 2019 | 31391120 |
| potential impact and cost-effectiveness of future etec and shigella vaccines in 79 low- and lower middle-income countries. | while diarrhea mortality in children has declined over the last two decades, there has been a slower decline in diarrheal episodes. repeated diarrheal episodes are associated with childhood stunting, which leads to increased mortality risk from infectious diseases. vaccine candidates are under development for enterotoxigenic escherichia coli [etec] and shigella, important enteric pathogens in children in low income countries. these future vaccines could significantly reduce diarrheal burden, pre ... | 2019 | 31384741 |
| quantifying trends and uncertainty in prehistoric forest composition in the upper midwestern united states. | forest ecosystems in eastern north america have been in flux for the last several thousand years, well before euro-american land clearance and the 20th-century onset of anthropogenic climate change. however, the magnitude and uncertainty of prehistoric vegetation change have been difficult to quantify because of the multiple ecological, dispersal, and sedimentary processes that govern the relationship between forest composition and fossil pollen assemblages. here we extend stepps, a bayesian hie ... | 2019 | 31381148 |
| the effect of reinsuring a deductible on pharmaceutical spending: a dutch case study on low-income people. | many countries have cost sharing schemes in health insurance to control health care expenditures. the dutch basic health insurance includes a mandatory deductible of currently 385 euros per adult per year. to avoid affordability problems, several municipalities offer a group contract for low-income people in which the mandatory deductible is 'reinsured'. more specifically, this means that out-of-pocket spending under the deductible is covered by supplementary insurance. by comparing groups with ... | 2019 | 31378537 |
| on-road emissions of passenger cars beyond the boundary conditions of the real-driving emissions test. | passenger cars are an important source of air pollution, especially in urban areas. recently, real-driving emissions (rde) test procedures have been introduced in the eu aiming to evaluate nitrogen oxides (nox) and particulate number (pn) emissions from passenger cars during on-road operation. although rde accounts for a large variety of real-world driving, it excludes certain driving situations by setting boundary conditions (e.g., in relation to altitude, temperature or dynamic driving). the p ... | 2019 | 31377567 |
| economic impact of contagious caprine pleuropneumonia and cost-benefit analysis of the vaccination programmes based on a one-year continuous monitoring of flocks in the arid and semi-arid lands of kenya. | in kenya and east africa, contagious caprine pleuropneumonia (ccpp) is one of the most prevalent infectious diseases affecting small ruminants in pastoral areas with adverse consequences on livelihoods. this is so despite the implementation of bi-annual vaccination campaigns. unfortunately, the impact of the disease and the cost-effectiveness of its prevention and control in a pastoral context have been difficult to assess due to a lack of reliable data. the dynamic of flock population, high ill ... | 2019 | 31376342 |
| cycling of people with a lower limb amputation in thailand. | to investigate cycling participation and barriers, and facilitators in adults with a lower limb amputation in thailand. | 2019 | 31374098 |
| the impact of the ambiguous definition of "month" on pharmacotherapy. | the gregorian calendar divides a common year into 12 months of irregular length. as a result, whenever time is measured in months, an unavoidable degree of inaccuracy exists. we hypothesize that the use of this unprecise measure of time has profound implications for the field of pharmacotherapy from practical and drug safety issues, to variations in drug budgets, and pharmacoepidemiological, industrial and drug regulatory considerations, such as price-fixing policies. in this paper, we have trie ... | 2019 | 31371075 |
| [decrease in foetal and neonatal mortality in the netherlands; comparison with other euro-peristat countries in 2004, 2010 and 2015]. | to compare changes in foetal, neonatal and perinatal mortality in the netherlands in 2015, relative to 2004 and 2010, with changes in other european countries and regions. | 2019 | 31361412 |
| wolfram syndrome: a rare case report. | we present an autopsy case of a 19 year old male admitted for breathlessness and oliguria. he was diabetic since 7 years of age and was on insulin. patient was on testosterone and anti hypertensives. he was diagnosed of hypocontractile bladder and congenital bilateral megaureter with vesico-ureteric reflux 2 years back. history of hemiparesis 2 years back. ct scan of the brain showed a right fronto- parietal healed infarct. at autopsy, bilateral kidneys showed coarse granularity and scarring. pe ... | 2019 | 31361246 |
| integration of cta in the diagnostic workup of new onset chest pain in clinical practice. | recently, nice guidelines recommend the use of computed tomographic angiography (cta) as the first line of investigation for new onset chest pain. we sought to evaluate the impact of the integration of cta in the diagnostic workup, as either a first- or second-line of investigation, in the clinical practice for patients presenting with new onset chest pain, with suspicion that it may be due to coronary artery disease (cad). | 2019 | 31360708 |
| atlantic origin of asynchronous european interdecadal hydroclimate variability. | discharge time series of major large-catchment european rivers are known to display significant decadal and interdecadal fluctuations. however, the hydroclimate variability causing such fluctuations remains poorly understood, particularly due to a lack of a spatio-temporal integrated assessment. here, we demonstrate for the first time that european hydroclimate variability is dominated by a meridional delayed oscillation characterized by a lag of approximately 5 years in interdecadal discharge f ... | 2019 | 31358832 |
| foodborne parasites in europe: present status and future trends. | although foodborne parasites (fbps) are becoming recognized as important foodborne pathogens, they remain neglected compared with bacterial and viral foodborne pathogens. as drivers for infection with fbps are variable, it is often unclear for funding bodies where research should be prioritized. through a cost action (euro-fbp; fa1408), we harnessed europe-wide expertise to address these questions, using an expert knowledge elicitation approach. eating habits, lack of food-chain control, lack of ... | 2019 | 31358427 |
| evaluation of phenolic compounds, antioxidant and antiproliferative activities of 31 grape cultivars with different genotypes. | this study evaluated the total phenolic content, phenolic composition, antioxidant and in vitro antiproliferative properties of seeds and skins of 31 different grape cultivars. these properties of seeds and skins varied greatly among grape cultivars. european grapes had the highest values of phenolic compounds, antioxidant properties in seeds followed by muscadine > american grapes > oriental grapes. european grape seed extracts also were the strongest in inhibiting the growth of hepg2 cell, fol ... | 2019 | 31353617 |
| systematic assessment of critical factors for the economic performance of landfill mining in europe: what drives the economy of landfill mining? | landfill mining (lfm) is a strategy to mitigate environmental impacts associated with landfills, while simultaneously recovering dormant materials, energy carriers, and land resources. although several case study assessments on the economy of lfm exist, a broader understanding of the driving factors is still lacking. this study aims at identifying generically important factors for the economy of lfm in europe and understanding their role in developing economically feasible projects in view of di ... | 2019 | 31351655 |
| the effects of copayment in primary health care: evidence from a natural experiment. | evaluate the effects of the 'euro per prescription' on primary health care services (number of doctor visits), through a retrospective cohort study of health care users in catalonia (spain). this policy, implemented in catalonia on 23 june 2012, only lasted 6 months. this policy was introduced to improve budgetary imbalances in spain and boost the regional and national governments' budgets. | 2019 | 31350623 |
| how much does saving femoral head cost after acetabular fracture? comparison between orif and tha. | we performed a prospective study on patients with acetabular fractures treated either with internal fixation either with arthroplasty comparing clinical outcomes, quality of life, economic resources and cost efficacy in the first five years after surgery. demographic data, diagnosis, index treatment, costs and subsequent surgeries were recorded. patients were requested to fulfill merle d'aubigné and eq-5d-5l questionnaires. clinical differences between treatments are significant only in discharg ... | 2019 | 32374241 |
| quality of life among patients with left ventricular assist device: comparison of two populations. | this study aims to evaluate quality of life among patients with an implanted left ventricular assist device in two different populations. | 2019 | 32551161 |
| ino therapy in patients with congenital diaphragmatic hernia - discrepancy between widespread use and therapeutic effects. | despite recent studies failing to prove beneficial effects of ino therapy in patients with cdh, its use is still widespread. the aim of this work was to analyze ino use in a retrospective cohort focusing on outcome parameters. patients 378 cdh patients born and treated in mannheim university medical center, department for neonatology, between 2010 and 2017 constituted our cohort. therapy was based on the standardized protocol of the cdh euro consortium. | 2019 | 31466085 |
| 7th euro evo devo meeting: report on the "evolution of regeneration in metazoa" symposium. | regeneration, the ability to restore lost parts of the body, is a widespread phenomenon in animals. while this ability is somehow limited in classical developmental model organisms, a variety of animals are able to regenerate complex structures such as limbs or important parts of their body, upon injury. despite the recent emergence of regenerative studies using a large variety of metazoans, we still lack a general view of the evolution of animal regeneration. in the context of the 7th evodevo m ... | 2019 | 31461214 |
| the economic burden of constipation therapy. | constipation is a widespread condition that requires adequate therapy. given the large use of laxatives, it is important to know the burden of the treatment of this condition on the healthcare budget. | 2019 | 31460507 |
| effect of low ambient temperature on emissions and electric range of plug-in hybrid electric vehicles. | plug-in hybrid electrical vehicles (phevs) are generally considered to be a cleaner alternative to conventional passenger cars. however, there is still very limited information available regarding criteria pollutant emissions from these vehicles. this paper shows, for the first time, the emissions of criteria pollutants, unregulated pollutants, and co2 and also electric range from two very different phevs, one euro 6 parallel plug-in hybrid and one range-extended battery electric vehicle (bevx), ... | 2019 | 31459533 |
| authors' correction for euro surveill. 2019;24(33). | 2019 | 31456561 | |
| comparison of hydrogenated vegetable oil and biodiesel effects on combustion, unregulated and regulated gaseous pollutants and dpf regeneration procedure in a euro6 car. | the effects of traditional biodiesel (fatty acid methyl-esters, fame) and a hydrotreated vegetable oil (hvo) were comprehensively investigated on a production euro 6 diesel car, including fuel injection rate and timing, combustion analysis, emissions of regulated and unregulated pollutants, and regeneration of the diesel particle filter. the use of both biofuels is a part of the efforts to reduce emissions of greenhouse gases and health-relevant pollutants and to improve energy security and sust ... | 2019 | 31454607 |
| soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells. | as global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. using human airway epithelial cells obtained from young children, we compared the effects of exposure to exhaust generated by a diesel engine with euro v/vi emission controls running on conventional diesel (ultra-low-sulfur mineral diesel, ulsd), soy biodiesel (b100), o ... | 2019 | 31453689 |
| characterization of gas and particulate phase organic emissions (c9-c37) from a diesel engine and the effect of abatement devices. | particulate and vapor phase emissions in the diluted exhaust of a light-duty diesel engine designed for euro 5 application have been sampled. the engine was operated in three modes, and samples were collected from the exhaust without aftertreatment but also with aftertreatment by an exhaust oxidation catalyst and particle filter. the samples were analyzed by two-dimensional gas chromatography with time-of-flight mass spectral detection. the results show overall removal efficiencies for the organ ... | 2019 | 31452363 |
| gluten-free products: from dietary necessity to premium price extraction tool. | every year, the italian national health service (nhs) provides about 200,000 celiac people (based on 2017 data) living in italy with financial support of about 250 million euro to cover the cost of their specific dietary constrains. the existence of gluten-free products of high quality and affordable price is very important for the quality of life of celiac people and the sustainability of public support. over the last decade, the market for gluten-free products has experienced a dramatic surge, ... | 2019 | 31450806 |
| a clustering approach to developing car-to-two-wheeler test scenarios for the assessment of automated emergency braking in china using in-depth chinese crash data. | two-wheeled vehicles (motorized and non-motorized, referred to as tws) are an important part of the transport system in china. they also represent an important challenge for road safety, with many tw user fatalities and injuries every year. recently, active safety systems for cars, such as automated emergency braking (aeb), promise to reduce road traffic fatalities and injuries. for these systems to work effectively, it is necessary to understand and define the complex traffic scenarios to be ad ... | 2019 | 31446097 |
| a case of orbital langerhans cell histiocytosis in an adult. | langerhans cell histiocytosis remains an enigmatic disease with a very heterogeneous presentation. we describe a rare case of orbital langerhans cell histiocytosis in a 39-year-old female patient who presented right orbital pain and edema of the upper right eyelid. surgery showed a friable lesion and underlying bone irregularity. morphological aspects and immunohistochemical profile favored the diagnosis of langerhans cell histiocytosis, which was confirmed with evidence of langerin expression. ... | 2019 | 31493367 |
| the relationship between early life urbanicity and depression in late adulthood: evidence from the survey of health, ageing and retirement in europe. | we aimed to study the association of childhood urbanicity with depressive symptoms in late adulthood. | 2019 | 31492779 |
| identification and weighting of kidney allocation criteria: a novel multi-expert fuzzy method. | kidney allocation is a multi-criteria and complex decision-making problem, which should also consider ethical issues in addition to the medical aspects. leading countries in this field use a point scoring system to allocate kidneys. hence, the purpose of this study is to identify and weight the kidney allocation criteria considering the balance between utility and equity. | 2019 | 31492132 |
| haemophilia a: health and economic burden of a rare disease in portugal. | haemophilia a is a hereditary bleeding disorder, which has been considered rare and chronic. the burden of this disease in portugal remains unknown. the aim of this study was to estimate the annualized cost and health burden of haemophilia a in portugal. | 2019 | 31484564 |
| prevalence of braf gene mutation in samples of primary and metastatic colorectal cancer: a meta-analysis. | understanding the prevalence and biology of braf gene can improve the treatment methods of cancerous patients. this study aims to estimate the prevalence of braf gene mutation in samples of primary and metastatic colorectal cancer using meta-analysis method. | 2019 | 31482595 |
| delay of transfer from the intensive care unit: a prospective observational analysis on economic effects of delayed in-house transfer. | intensive care unit (icu) capacity is a scant and precious resource in hospitals. therefore, an optimal occupancy rate as well as detailed occupation planning is of great importance. most literature deals with admission to the icu, while only few discuss discharge from the icu. specifically, a delay of transfer from the icu can cause a shortness of beds, jeopardize urgent patient treatment and lead to a decrease in treatment quality as well as economic downsides. this study examined the incidenc ... | 2019 | 31481124 |
| advantage of proton-radiotherapy for pediatric patients and adolescents with hodgkin's disease. | radiotherapy is frequently used in the therapy of lymphoma. since lymphoma, for example hodgkin's disease, frequently affect rather young patients, the induction of secondary cancer or other long-term adverse effects after irradiation are important issues to deal with. especially for mediastinal manifestations numerous organs and substructures at risk play a role. the heart, its coronary vessels and cardiac valves, the lungs, the thyroid and, for female patients, the breast tissue are only the m ... | 2019 | 31477141 |
| affective perception of euro banknotes: cognitive factors and interindividual differences. | money can be a tool to achieve a wide range of goals in everyday life. different studies have reported that both the mere exposure to money and its use as a reward can determine cognitive and social effects. nevertheless, little is known about the basic affective perception of euro banknotes. thus, in the present study we aim to assess differences in valence, arousal and familiarity evaluations of banknote pictures (from 5 to 500€) by taking into account gender, socioeconomic status and love of ... | 2019 | 31473804 |
| cost-effectiveness of extracorporeal cardiopulmonary resuscitation after in-hospital cardiac arrest: a markov decision model. | this study aimed to estimate the cost-effectiveness of extracorporeal cardiopulmonary resuscitation (ecpr) for in-hospital cardiac arrest treatment. | 2019 | 31473264 |
| clinical presentation, aetiology and outcome of infective endocarditis. results of the esc-eorp euro-endo (european infective endocarditis) registry: a prospective cohort study. | the euro-endo registry aimed to study the management and outcomes of patients with infective endocarditis (ie). | 2019 | 31504413 |
| economic evaluation of a home-based programme to reduce concerns about falls in frail, independently-living older people. | background: concerns about falls, or fear of falling, are frequently reported by older people and can have serious consequences. aim of this study was to evaluate the cost-effectiveness of a home-based, cognitive behavioral programme for independently-living, frail older people in comparison with usual care from a societal perspective. methods: this economic evaluation was embedded in a randomized-controlled trial with a follow-up of 12-months. in the trial 389 people aged 70 years or older were ... | 2019 | 31502897 |
| selective intracoronary hypothermia in patients with st-elevation myocardial infarction. rationale and design of the euro-ice trial. | 2019 | 31498112 | |
| prevalence and clinical correlates of dissociative subtype of posttraumatic stress disorder at an outpatient trauma clinic in south korea. | background: previous studies on of the dissociative subtype of posttraumatic stress disorder (d-ptsd) have relied on specialized statistical methods (i.e. profile or class analyses) for diagnosis than clinical rating available to clinicians. objective: this study investigated the prevalence and covariates of d-ptsd diagnosed by a semi-structured interview in a cohort of outpatients with dsm-iv ptsd in a specialized trauma clinic in south korea. method: data from 249 patients with civilian ptsd w ... | 2019 | 31528271 |
| fortification of preservation solution with nitroprusside does not alter lung allograft survival in clinical human lung transplantation. | background: nitric oxide improves gas exchange following primary lung allograft dysfunction. nitroprusside, a potent nitric oxide donor, has reduced reperfusion injury and improved oxygenation in experimental lung transplantation. methods: we sought to study the effect on lung allograft outcomes of fortifying the preservation solution with nitroprusside. we conducted a single-center clinical study of 46 consecutive lung recipients between 1998 and 2000: 24 patients received donor organs preserve ... | 2019 | 31528134 |
| use of non-hiv medication among people living with hiv and receiving antiretroviral treatment in côte d'ivoire, west africa: a cross-sectional study. | in côte d'ivoire, people living with hiv (plhiv) have free access to antiretroviral therapy (art) and cotrimoxazole. yet, they may use other medications to treat non-hiv diseases. scarce data are available regarding the use of non-hiv medications in africa. this study describes the use of non-hiv medications and identifies the factors associated with their use by plhiv on art in côte d'ivoire. | 2019 | 31525222 |
| dual control model in a cross-cultural context: role of sexual excitation in sexual response and behavior differences between chinese and euro-caucasian women in canada. | chinese women in western nations frequently report less engagement with sexuality, such as lower sexual response and behaviors, and more restrictive sexual attitudes, than their euro-caucasian peers. this difference is likely related to sexual conservatism within traditional chinese culture, though the mechanisms underlying how culture influences sexual responding are not well understood. the current study investigated if these differences were consistent with the dual control model, a well-esta ... | 2019 | 31520178 |
| a novel gc-fid analytical strategy reveals adulteration of fuels by vegetable oil. | background: adulteration of diesel fuel by the addition of vegetable oil is a problem that touches several countries around the world and bypasses the complexity of the specifications regarding the automotive diesel fuel distinguishing between customs, fiscal, and commercial-environmental specifications. at an international level, the adoption of the same analysis methods is important for the harmonization processes and the fluidity of the market. in this context, we assist to the diffusion of t ... | 2019 | 31533873 |
| [use of psychotherapy among adults with a history of suicide attempt: results form a large population-based study]. | the current study aims to identify the factors associated with the use of psychotherapy among adults with a history of suicide attempt. | 2019 | 31542213 |
| assessing sustainability performance in the educational sector. a high school case study. | this paper provides a detailed assessment of the environmental performance of a high school student in the city of madrid, as well as the associated external costs. life cycle assessment was used to evaluate the potential environmental impacts. environmental external costs were also estimated using a simplified application of the impact pathway approach. the inventory of environmental loads included the consumption of resources in the school building operation and maintenance (o&m) activities, i ... | 2019 | 31539963 |
| [the growing resistance of bacterial strains to antibiotics]. | understanding the mechanisms of bacterial resistance to antibiotics made it possible to divide this phenomenon into natural and acquired resistance. the natural resistance of the bacteria is related to the lack of antibiotic ability to penetrate into the interior of the bacteria and limit the ability of penetration through the cell wall, as well as the poor affinity of the drug for the receptor or the lack of such a receptor. the acquired bacterial resistance is related to the changes occurring ... | 2019 | 31557140 |
| cost-effectiveness of [18f] fluoroethyl-l-tyrosine for temozolomide therapy assessment in patients with glioblastoma. | background and purpose: glioblastomas are the most aggressive of all gliomas. the prognosis of these gliomas, which are classified as grade iv tumors by the world health organization (who), is poor. combination therapy, including surgery, radiotherapy, and chemotherapy has variable outcomes and is expensive. in light of rising healthcare costs, there are societal demands for the justification of medical expenses. therefore, we calculated the cost-effectiveness of follow-up [18f] fluoroethyl-l-ty ... | 2019 | 31555584 |
| pan-european groundwater to atmosphere terrestrial systems climatology from a physically consistent simulation. | applying the terrestrial systems modeling platform, tsmp, this study provides the first simulated long-term (1996-2018), high-resolution (~12.5 km) terrestrial system climatology over europe, which comprises variables from groundwater across the land surface to the top of the atmosphere (g2a). the data set offers an unprecedented opportunity to test hypotheses related to short- and long-range feedback processes in space and time between the different interacting compartments of the terrestrial s ... | 2019 | 31844064 |
| how to develop a sustainable telemedicine service? a pediatric telecardiology service 20 years on - an exploratory study. | telemedicine services are promoting more access to healthcare. portugal was an early adopter of telemedicine to overcome both its geological barriers and the shortage of healthcare professionals. the pediatric cardiology service (pcs) at coimbra university hospital centre (chuc) has been using telemedicine to increase access and coverage since 1998. their pediatric telecardiology service has been daily connecting chuc with 13 other portuguese national hospitals, and regularly connecting with por ... | 2019 | 31547824 |
| musculoskeletal ultrasound workshops in postgraduate physician training: a pre- and post-workshop survey of 156 participants. | use of ultrasonography has revolutionized diagnosis of musculoskeletal disorders. until now, few studies have investigated usefulness of a short-period workshop for musculoskeletal ultrasound (mskus) education. in this research, we attempted to explore (1) whether the physicians felt it useful to attend this type of courses for improving knowledge of sonoanatomy and scanning skills, (2) if the attendees' perceived confidence in musculoskeletal diagnoses by using ultrasound increased following th ... | 2019 | 31547816 |
| beyond the biological effect of a chemically characterized poplar propolis: antibacterial and antiviral activity and comparison with flurbiprofen in cytokines release by lps-stimulated human mononuclear cells. | bee propolis, especially euro-asian poplar propolis, is among the most well-known natural products traditionally used to treat pharyngitis and minor wounds. the aim of this research was to investigate the pharmacological properties responsible for poplar propolis effectiveness using, for the first time, different in vitro approaches applied to a chemically characterized sample. the anti-inflammatory activity was compared with flurbiprofen by determining pro-inflammatory cytokines released by lip ... | 2019 | 31546676 |
| educational icu antimicrobial stewardship model: the daily activities of the ams team over a 10-month period. | the emergence of antibiotic resistance as a consequence of inappropriate use results in higher mortality rates and has become a major public health challenge worldwide. antimicrobial stewardship programs (asps) aim to ensure proper use of antimicrobials and reduce health care costs. we assessed the impact of using a behavioral approach during a persuasive asp on antibiotic appropriateness, consumption and costs. we conducted a prospective interventional cohort before-and-after study in the inten ... | 2019 | 31545768 |
| [resource allocation effectiveness of indicator-based performance monitoring in hungarian primary care for adults]. | introduction: the indicator-based performance monitoring and pay-for-performance system for hungarian primary care was established in 2009, covering the whole country. it is based on a stable legal system and well operating information technology. although, the health insurance system is able to facilitate the performance improvement only by the financing for general medical practices, the many times modified present system does not take into consideration (apart from the geographical location o ... | 2019 | 31544494 |
| cooking up a transparent model following a dice recipe. | when a model is built, it tends to be an iterative process. the ideal model building process starts with constructing a top-level model (that works) and then digging deeper into the sections that need more details. a good model tends to have a long life and be both adapted and updated. a perfectly transparent first model (in whatever platform or programming language it might be) therefore tends to get increasingly convoluted. yet, it still needs to be submitted and reviewed since it will likely ... | 2019 | 31544217 |
| health implications of diverse visions of urban spaces: bridging the formal-informal divide. | in the past 200 years, urban spaces have been imagined as neatly laid out, well-planned, sanitised and civilised places of dense human habitation with regulated economic activity, where political power, financial capital, the frontiers of knowledge and technology thrive. this has been the urban planners dream, even while it does not reflect the full reality, whether of cities in the lmics or the hics. in the face of such homogenising visions arising from euro-american models, formal urban system ... | 2019 | 31544099 |
| characterization of laboratory and real driving emissions of individual euro 6 light-duty vehicles - fresh particles and secondary aerosol formation. | emissions from passenger cars are one of major sources that deteriorate urban air quality. this study presents characterization of real-drive emissions from three euro 6 emission level passenger cars (two gasoline and one diesel) in terms of fresh particles and secondary aerosol formation. the gasoline vehicles were also characterized by chassis dynamometer studies. in the real-drive study, the particle number emissions during regular driving were 1.1-12.7 times greater than observed in the labo ... | 2019 | 31542669 |
| ferric carboxymaltose for patients with heart failure and iron deficiency in italy: cost-effectiveness and budget impact. | aim: to evaluate the cost-effectiveness of intravenous ferric carboxymaltose (fcm) versus placebo for the management of iron deficiency in patients with chronic heart failure in the italian healthcare system and to estimate its impact on the national healthcare budget. materials & methods: a markov model was developed to project costs and health outcomes over 1 year, based on data from literature. healthcare resources consumption was derived from an e-survey administered to clinicians. costs wer ... | 2019 | 31580153 |
| machine learning-based fast banknote serial number recognition using knowledge distillation and bayesian optimization. | we investigated a machine-learning-based fast banknote serial number recognition method. unlike existing methods, the proposed method not only recognizes multi-digit serial numbers simultaneously but also detects the region of interest for the serial number automatically from the input image. furthermore, the proposed method uses knowledge distillation to compress a cumbersome deep-learning model into a simple model to achieve faster computation. to automatically decide hyperparameters for knowl ... | 2019 | 31569340 |
| idioms of distress, mental symptoms, syndromes, disorders and transdiagnostic approaches. | euro-american idioms of distress and their corresponding symptom clusters have been universalised as mental disorders and are now the gold standard for psychiatric diagnosis around the globe. this paper discusses issues related to mental disorder diagnosis from a cultural perspective. it argues that psychiatric diagnoses, while having good inter-rater reliability, lack external validity. it contends that psychiatric categories and labels are supported by the current political economy of health. ... | 2019 | 31568981 |
| associations between classification criteria items in systemic lupus erythematosus. | a project aimed at developing new classification criteria for systemic lupus erythematosus (sle) is based on weighted criteria that include both laboratory and clinical items. combinations of certain symptoms may occur commonly in sle, which provides an argument against independently counting these items. the current study was undertaken to evaluate the interrelationship between candidate criteria items in the international early sle cohort and in the euro-lupus cohort. | 2019 | 31560454 |
| cost, prevalence and correlates of cigarillo use in 28 european countries in 2017. | although manufactured cigarettes remain the most popular tobacco product worldwide, the use of other products, including little cigar and cigarillo, has been rising in recent years; however, there is a paucity of data on the correlates of current and ever use of cigarillos in europe. the aim of this study was to explore the extent and determinants of cigarillo use, as well as to describe the cost and affordability of cigarillos across the eu, in light of the current regulatory framework at a eur ... | 2019 | 31580551 |
| upper-tropospheric bridging of wintertime surface climate variability in the euro-atlantic region and northern asia. | a remarkable feature of interannual climate variability is a robust link of wintertime anomalies of surface air temperature (sat) in northern asia to pan-atlantic sat variations associated with the north atlantic oscillation (nao). here statistical analyses of data from the era of satellite observations (1979-2017) are used to show that about 80% of the variance of the winter (december-march) mean area-averaged sat anomalies in northern asia can be explained by the anomalous surface circulation ... | 2019 | 31601851 |
| the sensitivity of euro-atlantic regimes to model horizontal resolution. | there is growing evidence that the atmospheric dynamics of the euro-atlantic sector during winter is driven in part by the presence of quasi-persistent regimes. however, general circulation models typically struggle to simulate these with, for example, an overly weakly persistent blocking regime. previous studies have showed that increased horizontal resolution can improve the regime structure of a model but have so far only considered a single model with only one ensemble member at each resolut ... | 2019 | 31598020 |