Publications

[use of the coagglutination reaction for identifying shigella flexneri].	the data on the use of the coagglutination test for the identification of sh. flexneri are presented. the influence of different methods for the treatment of antisera on their heterologous reactions was studied and the advantage of coagglutinating reagents was revealed. 9 variants of coagglutinating preparations were obtained; their use made it possible to reduce the consumption of antisera and in some cases avoid their absorption. the problem of sh. flexneri classification is discussed.	1983	6194634
[quantitative determination of the soluble antigens of intestinal bacteria using a method of immunoenzyme analysis. i. processing of the parameters of the method].	the parameters of the assay based on the quantitative evaluation of the neutralization of specific antibodies by the antigen under study and the subsequent detection of free antibodies on the fixed reference antigen with the aim of the quantitative determination of the specific o-antigens of salmonella, groups d, b, c1, as well as those of shigella sonnei and shigella flexneri, have been developed. the proposed method makes it possible to detect the o-antigen of the causative agent at concentrat ...	1983	6195847
monoclonal antibodies specific for o-antigenic polysaccharides of shigella flexneri: clones binding to ii, ii:3,4, and 7,8 epitopes.	hybrid cells producing monoclonal antibodies against the o-antigens of shigella flexneri were obtained by polyethylene glycol-mediated fusion of myeloma cells and lymphocytes from balb/c mice immunized with whole heat-killed s. flexneri bacteria of serotypes 2a and 2b. clones were selected for their binding specificity to structurally defined s. flexneri lipopolysaccharides (lps). the following three groups were identified as recognizing three different epitopes: monoclonal antibodies binding to ...	1983	6196376
genetic transfer of a mucosal adherence factor (r1) from an enteropathogenic escherichia coli strain into a shigella flexneri strain and the phenotypic suppression of this adherence factor.	escherichia coli strain rdec-1 avidly adheres to rabbit ileal brush borders. two separate experiments were designed to determine whether pili promote this adherence. (1) adherence of strain rdec-1 was phenotypically suppressed by changing the culture medium. loss of adherence was correlated with the absence of pili. thus, growth of strain rdec-1 in penassay broth (difco laboratories, detroit, mich.) promoted both adherence and expression of pili on greater than or equal to 90% of organisms, wher ...	1983	6132950
antigenic relationship among virulent enteroinvasive escherichia coli, shigella flexneri, and shigella sonnei detected by elisa.		1983	6134933
immunologic observations in macaques with shigella-associated periodontal disease.		1983	6135769
changes in phage-sensitivity of shigella flexneri strains. ii. the f-like character of ms2-sensitive variants.	variants sensitive to male specific phage ms2 appeared among ms2 non-sensitive shigella flexneri cultures in the course of liquid medium passages. sensitivity to ms2 was lost on acridine orange treatment and was transferable into ms2 non-sensitive variants. the ms2 sensitive variants had fimbrial antigen. electron microscopy showed that ms2 phages were adsorbed on the f-like fimbriae of these variants. it was assumed that f-like plasmids determining f-like fimbrial antigen were carried by these ...	1983	6140808
an outbreak of campylobacter enteritis--a rheumatological followup survey.	one hundred and thirty individuals with bacteriologically proven campylobacter jejuni enteric infection in a single outbreak were studied. eighty-eight patients had gastrointestinal symptoms. one probable example of reactive arthritis was found. this is a frequency similar to that found in other comparable series of salmonella typhimurium and shigella flexneri infections, suggesting a common pathogenesis for the reactive arthritis associated with these 3 infections.	1983	6842468
rhodanese activity: a simple and reliable taxonomic tool for gram-negative bacteria.	the thiosulphate: cyanide sulphurtransferase (rhodanese) test of vandenbergh, bawdon and berk (1979) has been simplified and 2469 strains from a wide variety of sources representing different biochemical, serological or phage-pattern entities were tested. the percentages of rhondanese-producing strains were: escherichia coli 98%, shigella flexneri serovars 1-5%, x and y 0%, other shigellae 73-100%, yersinia spp. 0%, salmonella subgenera i-iv 0%, citrobacter freundi 16%, klebsiella 37%, enterobac ...	1982	6958873
[epidemiology and prevention of dysentery].		1982	7047217
[effect of b group vitamins on dysentery bacteria activity during stab culture].	the addition of the vitamin b complex into the culture medium enhances the productivity of the process ensuring the yield of biomass. the presence of the vitamins of this complex in the culture media intensifies the synthesis of some macromolecular compounds and prolongs the period of the physiological activity of the population.	1982	7048820
plasmid-mediated invasiveness of "shigella-like" escherichia coli.	invasive escherichia coli is a "shigella-like" microorganism which causes a dysenteric syndrome through invasion of the human colonic epithelium. representative strains of different serotypes were studied in order to determine whether plasmids are involved in their virulence. all invasive e. coli strains, irrespective of serotype, were found to harbour a large plasmid of approximately 140 mdal. spontaneous variants of serotypes o143 and o124 had lost this plasmid and had become avirulent, i.e. c ...	1982	7049041
shigella species from addis ababa: frequency of isolation and in vitro drug sensitivity.	one hundred and five shigella isolates from addis ababa were studied to determine serogroup frequency and in vitro antibacterial drug sensitivity. about 70% of the isolates were shigella flexneri followed by sh. dysenteriae (15%), sh. boydii (10%) and sh. sonnei (5%). all or most of the strains were susceptible to cephalothin, gentamicin, kanamycin, polymyxin b and trimethoprim-sulphamethoxazole. frequencies of susceptibility to ampicillin, carbenicillin and chloramphenicol were, respectively, 7 ...	1982	7057026
antibacterial substance from carica papaya fruit extract.	ripe and unripe carica papaya fruits (epicarp, endocarp, seeds and leaves) were extracted separately and purified. all the extracts except that of leaves produced very significant antibacterial activity on staphylococcus aureus, bacillus cereus, escherichia coli, pseudomonas aeruginosa and shigella flexneri. the mic of the substance was small (0.2-0.3 mg/ml) for gram-positive bacteria and large (1.5-4 mg/ml) for gram-negative bacteria. the substance was bactericidal and showed properties of a pr ...	1982	7097295
direct demonstration in intestinal secretions of an iga memory response to orally administered shigella flexneri antigens.		1982	7033378
[increased effectiveness of antibiotic therapy with adaptogens in dysentery and proteus infection in children].	the course of the disease and the host immunological reactivity (iga, igm, igg, cphi, igg and igm antibody titers in the hit, blood bactericidic properties) were studied in 258 children aged 0 to 14 year suffering from acute dysentery caused by shigella sonnei and flexneri and enterocolitis of the proteus etiology. 157 patients were treated with monomycin and kanamycin in combination with adaptogens, such as eleuterococcus and echinopanax elatum nakai l. and 101 patients were treated with the an ...	1982	7036851
adherence of shigella flexneri to guinea pig intestinal cells is mediated by a mucosal adhesion.	guinea pig colonic epithelial cells released by treating sections of the colon with solutions containing edta, dithiothreitol, and citrate avidly adhered shigella flexneri bacteria. separation of the intestinal cells from nonbound bacteria was achieved by differential sedimentation on a percoll gradient. adherence of s. flexneri to the colonic cells was ca2+ (1 mm) and time dependent. the ph optimum was ph 6.2, and almost no attachment (less than 5%) was observed at low temperature (4 degrees c) ...	1982	7040246
shigella enterocolitis and acute renal failure.	although acute renal failure secondary to infections is relatively common in adult patients, uremia requiring dialysis has not previously been reported in an adult patient with shigella enterocolitis. our patient, infected with s flexneri, had severe renal failure without any evidence of sepsis, rhabdomyolysis, or the hemolytic-uremic syndrome. antibiotic therapy with trimethoprim-sulfamethoxazole appeared to play a role in his eventual recovery.	1982	7041284
[local immunity in acute dysentery. ii. the content of antibody-forming cells in the large intestine mucosa in acute flexner dysentery in the dynamics of the disease].	antibody-forming cells were detected in the large intestine of patients with acute flexner's dysentery by means of the modified jerne - nordin method of hemolysis in agar. this method allowed one to determine the classes of immunoglobulins produced by the cells contained in tissue microspecimens obtained by the biopsy of the intestinal mucosa. the maximum amount of antibody-containing cells could be detected on days 7-12 of the disease. the content of antibody-forming cells was shown to depend o ...	1982	7043970
early colonic lesions in experimental shigella infection in rhesus monkeys: revisited.	rhesus monkeys (macaca mulatta), given 3 x 10(8) to 5 x 10(10) shigella flexneri 2a orally, developed signs of acute shigellosis within 24 hours. a diffuse acute colitis was well established at 48 hours. the inflammatory reaction was confined to the mucosa. the submucosa showed only edema. the shigellae were found predominantly in the columnar cells of the surface epithelium, less frequently in those of the crypt, and least frequently in the lamina propria. shigella bacilli invaded the columnar ...	1982	6153000
[obtaining dysentery and salmonellosis diagnostica for the coagglutination reaction in lyophilized form and the elaboration of a rapid system].		1982	6182376
[immunoelectrophoresis analysis of the antigenic composition of e. coli k12 hybrids which acquired the serological specificity of s. newcastle and s. flexneri].	genetic and immunoelectrophoretic studies confirm earlier data on the presence of 2 specific antigens of acidic nature in s. newcastle; one of them is a specific thermolabile k-antigen responsible for type iv specificity of these bacteria. the data concerning the differences in the genetic determinants controlling the synthesis of o- and k-antigens in s. newcastle have been obtained. s. newcastle o- and k-antigens did not react with s. flexneri in the group serum system 3, 4, which indicates tha ...	1982	6184914
[characteristics and trends in the development of an epidemic process of sonne and flexner dysentery among preschool children].	the results of studies indicate that the morbidity rates of dysentery among children attending preschool institutions and children brought up at home converged in recent years. this phenomenon was most pronounced among children of the kindergarten age group. at the same time dysentery caused by sh. sonnei and sh. flexnery produced a higher morbidity rate among children attending nursery in comparison with that among children of the same age group brought up at home. group infections in preschool ...	1982	6211010
[manifestations of the cyclic nature of the epidemic process in dysentery].	different forms of dysentery, especially those caused by sh. sonnei and sh. flexneri, have been found to differ considerably in their cyclic recurrence. the development cycles of the epidemic processes of dysentery have an objective character, occur in the presence of any tendencies in the morbidity rate, and depend on the natural factors. thus, the cycles of increase and decrease in morbidity are 3, 6, 9, 12 years for dysentery caused by sh. sonnei and 6, 7, 8 years for dysentery caused by sh. ...	1982	6213120
lipopolysaccharide receptor on rabbit peritoneal macrophages. i. binding characteristics.	the bordetella pertussis endotoxin, labeled with tritium ((3h)-lps), bound irreversibly and nonspecifically to rabbit lung macrophages, but bound reversibly and specifically to both resident and elicited rabbit peritoneal macrophages. the specific binding capacity of the macrophages was saturated with about 3 x 10(4) lps molecules per cell. the binding was inhibited with the homologous unlabeled endotoxin, but not at all with endotoxin from proteus mirabilis, thus assessing ligand specificity. e ...	1982	6278022
involvement of a plasmid in the invasive ability of shigella flexneri.	representative shigella flexneri strains were studied to determine whether plasmids are involved in their virulence. all invasive s. flexneri strains, irrespective of serotype, were found to harbor a large plasmid of approximately 140 megadaltons in size, although some strains carried additional plasmid species. spontaneous variants of strains of serotypes 1, 2, and 5 had lost this 140-megadalton plasmid and had concomitantly become avirulent, i.e., could neither invade hela cell monolayers nor ...	1982	6279518
attachment and ingestion of bacteria by trophozoites of entamoeba histolytica.	entamoeba histolytica trophozoites were found to be very selective in their interactions with bacteria. two principal mechanisms were shown to be responsible for these interactions. certain bacteria, such as a number of escherichia coli and serratia marcescens strains which are known to contain mannose-binding components on their cell surface, bound to mannose receptors on the amoeba membrane. this attachment was markedly inhibited by alpha-methylmannoside (0.5%), especially when the incubations ...	1982	6281192
degradation of intestinal glycoproteins by pathogenic shigella flexneri.	intestinal mucin glycoproteins were examined for their ability to sustain growth of pathogenic shigella. inoculation of germfree cecal mucin glycoproteins with shigella flexneri 4b resulted at 48 h in a 940-fold increase in the enteropathogen concentration. investigation in vitro of enzymatic degradation by the pathogen led to the identification of a blood group b-degrading glycosidase produced by the bacteria. in in vivo experiments, fecal supernatants of mice monocontaminated with s. flexneri ...	1982	6282754
[characteristics of the pkmr plasmids found in shigella flexneri].	the clinical isolate of sh. flexneri 1b, resistant to 5 antibiotics and sulfonamides, has been studied by the method of conjugation and found to have a group of transfer-suppressed pkmr-plasmids: pkmr 204-1 (ap sm tc cm km su), pkmr 204-2 (sm km su), pkmr 204-5 (km su) and pkmr 204-7 (sm tc cm km su), whose molecular weight was 99, 71.2, 73.8 and 59.5 md respectively. the treatment of the plasmids with restriction endonuclease bamhi has revealed that plasmids pkmr 204-2 and pkmr 204-5 are defini ...	1982	6285647
periodontal disease associated with shigella flexneri in rhesus monkeys. clinical, microbiologic and histopathologic findings.		1982	6124590
early colonic lesions in experimental shigella infection in rhesus monkeys: revisited.	rhesus monkeys (macaca mulatta), given 3 x 10(8) to 5 x 10(10) shigella flexneri 2a orally, developed signs of acute shigellosis within 24 hours. a diffuse acute colitis was well established at 48 hours. the inflammatory reaction was confined to the mucosa. the submucosa showed only edema. the shigellae were found predominantly in the columnar cells of the surface epithelium, less frequently in those of the crypt, and least frequently in the lamina propria. shigella bacilli invaded the columnar ...	1982	6755871
[fiéssinger-leroy-reiter syndrome. critical review propos of a case].		1982	6757850
[l-transforming effect of furazolidone on shigella flexneri cells].	the capacity of furazolidone for l-transformation of shigella flexneri was studied with its incubation on 1.3 per cent placenta serum salt difco agar. it was found that a single exposure of shigella cells to 0.05 microgram/ml of furazolidone resulted in transformation of some of them to the elements characteristic of the l-forms, i.e. spherical and granular forms capable of reproduction on routine nutrient media and possessing pronounced sensitivity to penicillin.	1982	6753734
[uptake of metals into the cadmium and zinc resistant shigella flexneri].		1982	6755006
[bacillary dysentery - 1980].		1982	6755564
[reiter's syndrome during shigella flexneri infection].		1982	6750449
[increased sensitivity of immune macrophages to the cytotoxic action of virulent shigellae].	the in vitro interaction of live bacteria belonging to virulent and avirulent shigella and salmonella strains with peritoneal macrophages obtained from mice immunized by the intragastric administration of these bacteria has been studied. in contrast to salmonella-activated macrophages capable of resisting the intracellular proliferation and the cytopathic action of homologous bacteria, shigella-activated macrophages become more sensitive to the cytopathic action of virulent shigellae. the abilit ...	1982	6750996
[effect of vaccination on the kinetics of the metabolism of radioactive iodine].		1982	6760245
new provisional serovar of shigella boydii.	ten bacterial strains are described that give biochemical reactions characteristic of the genus shigella but do not belong to any of the established or provisional serovars. the strains ferment mannitol and are antigenically indistinguishable. they do not possess any of the group antigens of shigella flexneri, and it is therefore proposed that they be regarded as members of a new provisional serovar of shigella boydii. strain e16553 is designated as the test strain for the new serovar.	1982	6761353
[biological properties of revertant l forms of shigella flexneri].		1982	6763383
gram-negative broth (hajna) for enrichment and isolation of yersinia enterocolitica.		1982	6763428
efficiency of immunoprophylaxis and immunotherapy by live dysentery vaccine administration in children and adults collectivities.		1982	6763515
bacillary dysentery in children below five years of age at the general hospital, manado.		1982	6763669
[antibacterial activity of 2 trimethoprim analogs (methioprim, brodimoprim) on recently isolated shigella].		1982	6764800
common evolutionary origin of chromosomal beta-lactamase genes in enterobacteria.	a 32p-labeled fragment of dna, encoding the major part of the chromosomal ampc beta-lactamase gene of escherichia coli k-12, was used as a hybridization probe for homologous dna sequences in colonies of neisseria gonorrhoeae, pseudomonas aeruginosa, and different enterobacterial species. the ampc probe detected the presence of homologous dna sequences in clinical isolates of e. coli, shigella flexneri, shigella sonnei, klebsiella pneumoniae, salmonella typhimurium, serratia marcescens, and p. ae ...	1982	6802795
[growth dyssymmetry of shigella flexneri 6(762 s) cells].	dyssymmetry in the growth of the initial and secondary shigella cells at early stages of the formation of microcolonies has been revealed by the method of dynamic morphometry in serial photographs obtained by time-lapse microfilming. electron-microscopic autoradiography has allowed revealing dyssymmetry in the assimilation of exogenous h3-thymidine, h3-threonine, h3-asparaginic acid by different halves of shigella cells in the process of their growth and preparation for mytosis. these results su ...	1982	6805178
experimental model of dysentery.	a method of producing experimental dysentery in rabbits has been developed. a prerequisite for this model is the fact that microscopic fungi eliminating biologically active substances are regularly found in the large intestine of man. using a rubber probe, the large intestine of rabbits was preliminarily irrigated with the filtrate of the aspergillus flavus fungus and subsequently, the suspension of a 24-hour culture of dysentery bacteria shigella flexneri was administered. a specific pathologic ...	1982	6806355
laboratory-acquired shigellosis.		1982	6809196
[studies on phagocytosis of shigella flexneri by peritoneal macrophages (author's transl)].		1982	6809853
[tropical diseases treated at the infection observation department of the un armed forces hospital in the middle east during the first and the last (xii) troop change].		1982	6817387
[case of vulvovaginitis due to shigella flexneri 2a].		1982	6818298
[diagnosis and treatment of reticulosarcomas of the stomach].		1982	351273
bender gestalt signs as indicants of conceptual impulsivity.	sixty children were individually administered the matching familiar figures test and the bender gestalt test. the mean age of the subjects was 10 years, 11 months. a significant relationship was found between errors on the bender gestalt test and impulsivity. more specifically, increased or decreased loops (figure four or six), change in angulation, loops for circles and circles for dots or dots for circles were all significantly related to children's impulsivity.	1982	351161
paul revere.		1982	351231
[hundred year anniversary of dentistry; past, present and future].		1981	351442
cell-mediated immune responses of synovial mononuclear cells to sexually transmitted, enteric and mumps antigens in patients with reiter's syndrome, rheumatoid arthritis and ankylosing spondylitis.	3h-thymidine uptake responses by synovial mononuclear cells to stimulation with sexually transmitted, enteric and mumps antigens were studied in 12 patients with "sexually transmitted reiter's syndrome", 5 with "enteric reiter's syndrome", 5 with rheumatoid arthritis, 4 with ankylosing spondylitis and 10 with "indolent arthritis of one knee." the "sexually transmitted" and salmonella cases were distinguishable by the responses. synovial responses were sometimes marked when peripheral blood respo ...	1981	6785434
[antibacterial properties of amniotic fluid in relation to selected bacterial strains].		1981	6788654
increase in drug resistance among shigella dysenteriae, sh flexneri, and sh boydii.	two thousand three hundred and seventy strains of shigella dysenteriae, sh flexneri, and sh boydii isolated in england and wales from 1974 to 1978 were tested for resistance to 12 antimicrobial drugs. eighty per cent of strains were resistant to one or more drugs, with sulphonamide resistance occurring most frequently. resistance to streptomycin, tetracycline, ampicillin, and chloramphenicol increased during the period, as did the incidence of multiple resistance. most infections due to sh dysen ...	1981	6790085
endotoxin inhibition of macrophage-mediated bone resorption.		1981	6791790
[immunoglobulins a and g in the intestinal secretions of rats in different microbiologic conditions].	experiments were made with 3 groups of inbred cdf (f344) crl rats: 30 germ-free, 30 conventional and 18 germ-free animals infected orally with shigella flexneri 2an 516. secretory iga (s-iga) was isolated from gut secretion of the conventional rats to obtain rabbit antiserum against it. the levels of s-iga, iga and igg in blood serum and gut secretion were determined. it was shown that gut secretion of the germ-free rats contained no less s-iga than that from the conventional rats, at the same t ...	1981	6794663
[antagonism between virulent and avirulent shigella or escherichia coli (author's transl)].		1981	6798142
[use of the indirect hemagglutination test for the diagnosis and epidemiological analysis of acute intestinal diseases].		1981	6764969
[efficacy of using the indirect hemagglutination test and tsuverkalov's test in the diagnosis of dysentery].		1981	6764972
[use of the indirect hemagglutination and antibody neutralization reactions in the epidemiological investigation of diseases of dysenteric etiology].		1981	6764973
shigella flexneri bacteremia: a case report.		1981	6753357
bacteriological and epidemiological approach to prophylaxis for enteric infection. effects of peritoneal cells from immunized animals on the infectivity of shigella bacillus to hela cells.		1981	6759764
[effect of mutations imparting resistance to antibiotics having different mechanisms of action on the virulence of shigella flexneri].	the study of the interaction between mutants of sh. flexneri 2a and epithelial hela cells has revealed that in all cases the loss of virulence in the studied groups of mutants, resistant to antibiotics with different mechanisms of action (polymyxin m, mecillinam and neamin) was linked with the loss of the ability of bacteria to penetrate into epithelial cells. these changes are probably the result of disturbances in the structure of external membrane in polymyxin-resistant mutants, in the regula ...	1981	6269334
serological analysis of core oligosaccharides of shigella flexneri serotype 6 and its r mutants lipopolysaccharides.	the core oligosaccharides originating from shigella flexneri 6 s strains and r mutants were examined by the complement fixation inhibition and passive hemolysis inhibition tests using antisera against the complete and partially degraded core regions. strong cross reactivity between shigella flexneri 6, shigella sonnei phase ii and e. coli c core fractions which all are of r1 type was observed. terminal beta-d-glucosyl groups and alpha-d-galactosyl-1,2-alpha-d-galactosyl sequences are essential e ...	1981	6181755
[properties of shigellae relevant to food hygiene].		1981	7044337
[shigellosis in pediatric wards].		1981	7042492
[etiological factors in bacillary dysentery in poland 1965-1979].		1981	7041196
[participation of cyclic nucleotides, ca ions and gastrin in the pathogenesis of the diarrheal syndrome in acute dysentery].		1981	7038902
[separation of shigella toxins into fractions differing in biological activity and characteristics of the fractions inducing penetration in avirulent strains].	the results obtained in the study of the biological activity of the lysates of 14 sh. flexneri and sh. sonnei strains differing in their virulence are presented. in the lysates of the virulent cultures 2 kinds of biological activity corresponding to the fractions of peaks i and ii could be detected: one fraction possessed hela toxicity, the other fraction possessed enterotoxic activity. the avirulent nonpenetrating mutants had no hela toxicity, but retained their capacity for producing factors s ...	1981	7034411
[antigenic characteristics of a preparation obtained by a non-destructive method from shigella flexneri and shigella sonnei].		1981	7034415
[liver and kidney function after immunization with an enteral vaccine from shigella flexneri and shigella sonnei antigens (blood biochemical test data)].		1981	7034416
[physicochemical characteristics of transfer derepressed pkmr plasmids].	a group of transfer derepressed r factors (pkmr plasmids) was identified with the methods of conjugation and transformation in 2 antibiotic resistant strains of the dysentery bacillus, i. e. shigella flexneri 3c and sh. sonnei isolated from patients with acute dysentery. the antibiotic resistance in s. flexneri was controlled by plasmid pkmr 202-2 (sm tc cm km su) with a molecular weight of 59 md and that in sh. sonnei was controlled by 2 plasmids, i. e. pkmr 203-2 (ap sm tc cm km su) and pkmr 2 ...	1981	7034638
towards serodiagnosis of serratia marcescens infections: examination of sera from noninfected patients and from experimentally infected rabbits for anti-h and anti-o antibodies; s. marcescens o-antigen cross-reactions with those of other enterobacteriaceae.	sera from 100 patients not infected with serratia marcescens at the time of hospital admission lacked detectable h-immobilizing antibodies against all 20 currently recognized h-antigens of this microorganism. however, various patient sera revealed elevated titers of o-agglutinins against several of the 20 o-antigens of s. marcescens, in a particular o-antigens, o1, o3, o4, o5, o7, o8, o10, o11, o16, o17, o18, o19, and o20. rabbit anti-shigella serogroup b immune serum cross-reacted with s. marce ...	1981	7036590
[an oral enteritis-vaccine composed of twelve heat-inactivated enterobacteriaceae 3. communication: studies on efficacy tests in mice protection tests (author's transl)].	the polyvalent vaccine consists of twelve heat-inactivated species of enterobacteriaceae (six strains of salmonellae, two strains of shigellae, four strains of dyspepsia coli). the above vaccine is administered orally (6) to man for prophylactic purposes against local infections. the present communication describes the efficacy results of the vaccine obtained for different parameters by the mouse protection test. for this purpose, seven different infection models were used: oral infection with a ...	1981	7036591
seroepidemiological studies with campylobacter fetus.	324 sera from unselected male and 581 sera from female patients as well as 268 sera from prostitutes were studied for antibodies against campylobacter fetus using the complement fixation test. antigen was campylobacter fetus subspecies intestinalis. 3.9% of the sera showed low but relevant antibody titers. statistically significant differences don't exist between the three population investigated. serological cross reactions could not be observed using salmonella typhimurium, shigella flexneri, ...	1981	7036594
[use of live flexner 2a 516m dysentery vaccine for the immunotherapy of acute and chronic dysentery].	live dysentery vaccine prepared from sh. flexneri 2a 516 m, a spontaneous mutant, was used for the treatment of 153 patients with acute and chronic dysentery. a single oral administration in a dose of 25 x 10(9) live microbial cells and 2 oral administrations in doses of 25 x 10(9) and 50 x 10(9) live microbial cells did not induce the clinical aggravation of the disease, greatly reduced the time of the reparation of the intestinal mucosa and reduced the frequency and duration of excretion of th ...	1981	7036601
proliferation of enteropathogens in oral rehydration solutions prepared with river water from honduras and surinam.	oral rehydration of infants with diarrhoea is an effective therapy that is becoming increasingly available in developing countries. to formulate judicious recommendations for preparation and storage of such solutions, we assessed the capability of recognized bacterial enteropathogens to survive and proliferate in solutions made either with sterile distilled or river water collected in two developing countries. shigella flexneri, an enteropathogen typically transmitted by faecal/oral contact rath ...	1981	7299876
reiter's syndrome following epidemic shigellosis.	to define the epidemiology of post-dysenteric reiter's syndrome (rs), 1,162 persons were questioned about compatible symptoms soon after 3 separate outbreaks of shigellosis. we diagnosed rs for 3 women of 204 persons ill during an outbreak of shigella flexneri 1b, for 3 women of 206 ill during an outbreak of s. flexneri 2a, and for none of 85 ill during an outbreak of s. sonnei. we found no rs among 667 persons without diarrhea. prospective controlled investigations in defined populations docume ...	1981	6948959
conjunctivitis and ethmoiditis due to shigella flexneri in an infant.		1981	7009020
splenic abscess and hepatic dysfunction caused by shigella flexneri.		1981	7009818
[shigella bacteremia. report of three cases].	shigella bacteremia is very uncommon, although it is known to occur in shigella infection. three cases of shigella flexneri bacteremia are reported, two of them diagnosed at the residencia ntra. sra. de aránzazu of san sebastián, and another at the ciudad sanitaria francisco franco of barcelona. in spite of the frequency of shigella infections in spain, no cases of shigella bacteriemia had been heretofore reported from our country. one of the patients was an alcoholic woman who died in coma and ...	1981	7010019
protein synthesis in hela or henle 407 cells infected with shigella dysenteriae 1, shigella flexneri 2a, or salmonella typhimurium w118.	the incorporation of [14c]leucine into protein was studied in two mammalian cell lines which had been infected with strains of shigella dysenteriae 1, shigella flexneri 2a, or salmonella typhimurium w118. these cell lines differed in susceptibility to the effects of exogenously applied shiga cytotoxin. all invasive shigella strains (which synthesize this toxin to a greater or lesser degree) were found to inhibit protein synthesis in both cell lines with equal efficiency. leucine accumulation con ...	1981	7012026
oxygen as a product of water radiolysis in high-let tracks. ii. radiobiological implications.		1981	7012902
role of antigen form in development of mucosal immunoglobin a response to shigella flexneri antigens.	one major stumbling block in the development of an effective means to immunize against shigellosis and other enteric diseases has been the lack of a means to assess sequential mucosal immune responses to different potential immunogens. in the present study, we compared the abilities of live invasive organisms, noninvasive organisms, and nonviable antigen preparations of shigella to elicit mucosal immune responses. whereas previous studies have found that effective immunity was produced best by v ...	1981	7014458
[effect of the products of the viral activities of shigellae on the physicochemical properties of blood plasma proteins in experimental animals].		1981	7015080
[severity of the clinical manifestations of sonnei an flexner dysentery].		1981	7015757
[study of enteric dysentery vaccines and their efficacy on a rabbit intestinal loop model. ii. changes in the mucosa of rabbit small intestine after oral immunization with live and chemical vaccines].	ten days after oral immunization of 3 groups of rabbits with live vaccine prepared from the mixture of streptomycin-dependent mutants of sh. flexneri 2a and sh. sonnei, with sh. flexneri and sh. sonnei tryptic lysate, or with boivin's extract of 6 sh. flexneri and sh. sonnei serotypes, a pronounced activation of the secretory and lysosomal apparatus was observed in ileac enterocytes. deteriorating bacteria or their antigenic material was observed in ileac enterocytes. deteriorating bacteria of t ...	1981	7015764
pattern of shigella flexneri serotypes and drug-resistance in dacca.		1981	7016755
shigella and shigellaemia.	two cases of bacteraemia with shigella flexneri 2a in children are described. they illustrate the wide variety of clinical manifestations of shigellosis, ranging from benign gastroenteritis to septicaemia associated with severe extra-intestinal manifestations.	1981	7017908
[obtaining shigella flexneri 2a mutants defective in utilization of certain carbon sources, their genetic and biological characteristics].	various methods, including selection by resistance to the antibiotic mecillinam have been used to obtain sh. flexneri mutants capable of utilizing mannitol and mannose as the sources of carbon. the mutation which determines this phenotype is localized in str-spc area and cotransduced with str a gene (28-33%). the appearance of this mutation in the initial sh. flexneri strain 516 led to a decrease in the virulence of this strain for guinea-pigs. the restoration of its properties and the partial r ...	1981	7018130
[etiologic structure of dysentery in cheliabinsk and its relation to the morbidity level and bacteriologic confirmation].		1981	7018138
[radiologic examination in shigellosis (author's transl)].		1981	7018357
salmonella and shigella surveillance in hungary, 1972-1976. ii. shigella surveillance.	shigellae were isolated from 32 399 persons in the bacteriological laboratories of the public health stations between 1972-1976. the number of isolations ranged between 5325 and 8237 yearly. as s. dysenteriae and s. boydii serotypes occurred only in about 1.5% of all isolations, the epidemiological situation was determined by the incidence of s. flexneri and s. sonnei. except in 1973, s. sonnei constituted the majority in every year. s. sonnei predominance, observed first in the western regions ...	1981	7020354
[effect of a pulsatile magnetic field on shigella flexneri].		1981	7023140
[oral intestinal vaccines and their effectiveness in the rabbit intestinal loop model. iii. effectiveness of oral immunization with live and chemical vaccines].	the effectiveness of the oral immunization of rabbits was manifested by a decrease in the number of virulent shigella penetrating enterocytes, by the limited proliferation of bacteria in the epithelium and by the less pronounced ulcerous inflammation of the mucous membrane in the intestinal loops even after infection with large doses (10(9) bacteria). in electron microscopy this was manifested by the destruction of shigella cells in heterophagosomes formed in enterocytes. the degree of fluid acc ...	1981	7023143
[transformation reaction study of e. coli competence].		1981	7023154