Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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quality of life in the treatment of chronic kidney disease: a challenge. | 2018 | 29319757 | |
the relationship between humidity, light and the activity pattern of a velvet worm, epiperipatus sp. (onychophora: peripatidae), from bahía drake, south pacific of costa rica. | even though the onychophora represent a whole phylum, observations of their activity pattern in nature are almost non-existent. here we report on the relationship between humidity and light and activity pattern of a new species of velvet worm, genus epiperipatus, from four years of field observations in the south pacific of costa rica. we found that most activity occurs during the driest and darkest nights of the year, in contrast with theoretical predictions. | 2018 | 29319749 |
short version of the "instrument for assessment of stress in nursing students" in the brazilian reality. | validate a short version of the instrument for assessment of stress in nursing students in the brazilian reality. | 2018 | 29319745 |
urinary incontinence in hospital patients: prevalence and associated factors. | to analyze the prevalence of urinary incontinence and its associated factors in hospital patients. | 2018 | 29319744 |
[18f]pbr111 pet imaging in healthy controls and schizophrenia: test - retest reproducibility and quantification of neuroinflammation. | activated microglia express the translocator protein (tspo) on the outer mitochondrial membrane. 18f-pbr111 is a second-generation positron emission tomography (pet) ligand that specifically binds the tspo, allowing in-vivo visualization and quantification of neuroinflammation. the aim of this study is to evaluate if the test-retest variability of 18f-pbr111 in healthy controls is acceptable to detect a psychosis-associated neuroinflammatory signal in schizophrenia. methods: dynamic 90-min 18f-p ... | 2018 | 29326362 |
draft genome sequence of chryseobacterium mucoviscidosis sp. nov. strain vt16-26, isolated from the bronchoalveolar lavage fluid of a patient with cystic fibrosis. | we report here the draft genome sequence of chryseobacterium mucoviscidosis vt16-26, a novel bacterium isolated from the lungs of a patient with cystic fibrosis. the genome was composed of 4,403,956 bp and had 36.2% g+c content. we detected 4,048 genes with predicted protein-coding functions, including those associated with antibiotic resistance and virulence. | 2018 | 29326226 |
complete genome sequence of thermoanaerobacterium sp. strain rbiitd, a butyrate- and butanol-producing thermophile. | thermoanaerobacterium sp. strain rbiitd was isolated from contaminated rich growth medium at 55°c in an anaerobic chamber. it primarily produces butyrate as a fermentation product from plant biomass-derived sugars. the whole-genome sequence of the strain is 3.4 mbp, with 3,444 genes and 32.48% gc content. | 2018 | 29326212 |
draft whole-genome sequence of deinococcus sp. ur1, a putative novel species isolated from an external stainless steel surface in the canadian prairies. | deinococcus sp. strain ur1, a resilient bacterium isolated from the surface of a stainless steel sign located on the university of regina campus in saskatchewan, canada, was sequenced to 56-fold coverage to produce 73 contigs with a consensus length of 4,472,838 bp and a g+c content of 69.37%. | 2018 | 29326211 |
complete genome sequencing of acinetobacter sp. strain logew2-3, isolated from the pellet of a white stork, reveals a novel class d beta-lactamase gene. | whole-genome sequencing of acinetobacter sp. strain logew2-3, isolated from the pellet of a white stork (ciconia ciconia), reveals the presence of a plasmid of 179,399 bp encoding a crispr-cas (clustered regularly interspaced short palindromic repeats and associated genes) system of the i-f type, and the chromosomally encoded novel class d beta-lactamase oxa-568. | 2018 | 29326210 |
draft genome sequence of the filamentous fungus hypoxylon pulicicidum atcc 74245. | hypoxylon pulicicidum strain mf5954 (atcc 74245) (formerly classified as nodulisporium sp.) is a filamentous fungal species known for its production of the secondary metabolite nodulisporic acid a. we present here the 41.5-mb draft genome sequence for this organism. | 2018 | 29326208 |
round robin study to evaluate the reconstructed human epidermis (rhe) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts. | 2018 | 29326048 | |
outcomes of more than 1,000 percutaneous nephrolithotomies and validation of guy's stone score. | to present the experience with percutaneous nephrolithotomy (pcnl) at a high-volume brazilian centre and to evaluate guy's stone score (gss) as a predictor of success and complications in pcnl. | 2018 | 29322602 |
a pure 21q22.3 deletion identified in a patient with mild phenotypic features. | partial deletions at the chromosome 21 have been rarely reported and in the majority of descriptions are associated with ring chromosome 21, resulting in terminal deletions of 21q22.3 and a large phenotypic variability (roberson et al.,2011). | 2018 | 29322562 |
structural integrity of synechocystis sp. pcc 6803 phycobilisomes evaluated by means of differential scanning calorimetry. | phycobilisomes (pbss) are supramolecular pigment-protein complexes that serve as light-harvesting antennae in cyanobacteria. they are built up by phycobiliproteins assembled into allophycocyanin core cylinders (ensuring the physical interaction with the photosystems) and phycocyanin rods (protruding from the cores and having light-harvesting function), the whole pbss structure being maintained by linker proteins. pbss play major role in light-harvesting optimization in cyanobacteria; therefore, ... | 2018 | 29322483 |
the genus coccidella hambleton (hemiptera: rhizoecidae) with description of two new species. | a study was conducted on the neotropical scale insect genus coccidella hambleton (hemiptera: coccomorpha: rhizoecidae) based on soil sample material deposited at the hungarian natural history museum. descriptions of the adult females of two new coccidella species, i.e., coccidella hexapora kaydan & konczné benedicty, sp. n. and coccidella kozari kaydan & szita, sp. n., are provided, plus a redescription and illustration of adult female of coccidella kissbalazsi konczné benedicty & kozár. an iden ... | 2018 | 29322381 |
detection of β-lactamase encoding genes in feces, soil and water from a brazilian pig farm. | β-lactam antibiotics are widely used for the treatment of different types of infections worldwide and the resistance to these antibiotics has grown sharply, which is of great concern. resistance to β-lactams in gram-negative bacteria is mainly due to the production of β-lactamases, which are classified according to their functional activities. the aim of this study was to verify the presence of β-lactamases encoding genes in feces, soil, and water from a brazilian pig farm. different β-lactamase ... | 2018 | 29322334 |
a new microsporidium fibrillaspora daphniae g. n. sp. n. infecting daphnia magna (crustacea: cladocera) in siberia and its taxonomic placing within a new family fibrillasporidae and new superfamily tubulinosematoidea (opisthosporidia: microsporidia). | infection with a new microsporidium, fibrillaspora daphniae g. n. sp. n., was found in a local daphnia magna population in tomsk region (western siberia, russia) at the prevalence rate of 52%. histological sections showed parasite cells entirely encompassing the host haemocoel. methanol-fixed spores were elongate, oval, 4.8 ± 0.3 μm × 2.3 ± 0.2 μm in size. all developmental stages were in direct contact with the host cell cytoplasm, with single nuclei, and division by binary fission. the sporont ... | 2018 | 29322298 |
a novel passerivirus (family picornaviridae) in an outbreak of enteritis with high mortality in estrildid finches (uraeginthus sp.). | an enteric outbreak with high mortality (34/52, 65.4%) was recorded in 2014 in home-reared estrildid finches (estrildidae) in hungary. a novel passerivirus was identified in a diseased violet-eared waxbill using viral metagenomics and confirmed by rt-(q)pcr. the complete genome of finch picornavirus strain waxbill/db01/hun/2014 (mf977321) showed the highest amino acid sequence identity of 38.9%, 61.6%, 69.6% in p1cap, 2chel and 3cprodpol, respectively, to passerivirus a1 (gu182406). a high viral ... | 2018 | 29322272 |
halorubrum depositum sp. nov., a novel halophilic archaeon isolated from a salt deposit. | a non-motile, pleomorphic rod-shaped or oval, red-pigmented (nearly scarlet), extremely halophilic archaeon, strain y78t, was isolated from a salt deposit of yunnan salt mine, china. analysis of the 16s rrna gene sequence showed that it was phylogenetically related to species of the genus halorubrum, with a close relationship to halorubrum rutilum yj-18-s1t (98.6%), halorubrum yunnanense q85t (98.3%), and halorubrum lipolyticum 9-3t (98.1%). the temperature, nacl, and ph ranges for growth were 2 ... | 2018 | 29322241 |
migration of paraburkholderia terrae bs001 along old fungal hyphae in soil at various ph levels. | the movement of bacterial cells along with fungal hyphae in soil (the mycosphere) has been reported in several previous studies. however, how local soil conditions affect bacterial migration direction in the mycosphere has not been extensively studied. here, we investigated the influence of two soil parameters, ph and soil moisture content, on the migration, and survival, of paraburkholderia terrae bs001 in the mycosphere of lyophyllum sp. strain karsten in microcosms containing a loamy sand soi ... | 2018 | 29322230 |
exploring physical and chemical properties in new multifunctional indium-, bismuth-, and zinc-based 1d and 2d coordination polymers. | main group element coordination polymers (mge-cps) are important compounds for the development of multifunctional materials. however, there has been a shortage of studies regarding their structural, optical, catalytic, mechanical, and antibacterial properties. this work presents an exhaustive study of a set of crystalline mge-cps obtained from bismuth and indium metals and iminodiacetate, 1,2,4,5-benzenetetracarboxylate, and 2,2'-bipyridine as building blocks. an in-depth topological analysis of ... | 2018 | 29322149 |
mixotrophic transition induced lipid productivity in chlorella pyrenoidosa under stress conditions for biodiesel production. | influence of mixotrophic mode and its transition to various trophic modes under stress conditions was assessed during two stage cultivation of chlorella pyrenoidosa. significant lipid productivity was triggered under low light intensity, glucose + bicarbonate supplementation and nitrogen starvation. the association between biomass and lipid productivity, fatty acid composition during mixotrophic transition was critically evaluated. biomass in growth phase (gp) and stress phase (sp) was 6.14 g/l ... | 2018 | 29322110 |
high-fat/high-sucrose diet results in higher bone mass in aged rats. | intake of high-fat/high-sucrose (hfs) diet or high fat diet influences bone metabolism in young rodents, but its effects on bone properties of aged rodents still remain unclear. this study aimed to examine the effects of hfs diet intake on trabecular bone architecture (tba) and cortical bone geometry (cbg) in aged rats. fifteen male wistar rats over 1 year were randomly divided into two groups. one group was fed a standard laboratory diet (sld) and the other group was fed a hfs diet for six mont ... | 2018 | 29322073 |
noncontiguous finished genome sequence and description of mediterranea massiliensis gen. nov., sp. nov., a new member of the bacteroidaceae family isolated from human colon. | strain marseille-p2645t was isolated in a colon sample from a frenchwoman who underwent a colonoscopy. bacterial cells were gram negative, non-spore forming, mobile and strictly anaerobic. the genome of strain marseille-p2645t is 3 950 441 bp long and contains 3374 protein-coding genes. the dna g+c content is of 51.66 mol%. strain marseille-p2645t exhibited a 92.9% sequence similarity with bacteroides helcogenes strain p36-108t (genbank accession no. cp002352), the phylogenetically closest speci ... | 2018 | 29321938 |
reevaluation of the dentary structures of caenagnathid oviraptorosaurs (dinosauria, theropoda). | among the characters of caenagnathid oviraptorosaurians, the lateral occlusal grooves and ridges on the occlusal surface of the jaw bones often receive special attention. recent studies demonstrated that ontogenetic edentulism is present in caenagnathids, and therefore the lateral occlusal grooves and ridges are vestigial alveoli and interdental septa, respectively. in the present paper, the dentary structures of caenagnathids were reevaluated based on ct images of caenagnathiasia sp. ivpp v2037 ... | 2018 | 29321606 |
microbial habitability of europa sustained by radioactive sources. | there is an increasing interest in the icy moons of the solar system due to their potential habitability and as targets for future exploratory missions, which include astrobiological goals. several studies have reported new results describing the details of these moons' geological settings; however, there is still a lack of information regarding the deep subsurface environment of the moons. the purpose of this article is to evaluate the microbial habitability of europa constrained by terrestrial ... | 2018 | 29321597 |
phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture. | the fundamental question of whether different microbial species will co-exist or compete in a given environment depends on context, composition and environmental constraints. model microbial systems can yield some general principles related to this question. in this study we employed a naturally occurring co-culture composed of heterotrophic bacteria, halomonas sp. hl-48 and marinobacter sp. hl-58, to ask two fundamental scientific questions: 1) how do the phenotypes of two naturally co-existing ... | 2018 | 29321512 |
the effect of nutritional intervention on the lipid profile and dietary intake of adolescents with juvenile systemic lupus erythematosus: a randomized, controlled trial. | objective this study sought to evaluate the effects of a nutritional intervention on the lipid metabolism biomarkers associated with cardiovascular risk, and their variation over time, in juvenile systemic lupus erythematosus (jsle) patients. this study also investigated the relationships between these biomarkers and dietary intake, nutritional status, disease variables, and medication used. methods a total of 31 10- to 19-year-old female adolescents with jsle for at least six months were analyz ... | 2018 | 29320971 |
the profiles of soluble adhesion molecules in the "great obstetrical syndromes". | the objective of this study was to determine the profiles of maternal plasma soluble adhesion molecules in patients with preeclampsia, small-for-gestational-age (sga) fetuses, acute pyelonephritis, preterm labor with intact membranes (ptl), preterm prelabor rupture of the membranes (preterm prom), and fetal death. | 2018 | 29320948 |
second-order raman scattering in exfoliated black phosphorus. | second-order raman scattering has been extensively studied in carbon-based nanomaterials, for example, nanotube and graphene, because it activates normally forbidden raman modes that are sensitive to crystal disorder, such as defects, dopants, strain, and so forth. the sp2-hybridized carbon systems are, however, the exception among nanomaterials, where first-order raman processes usually dominate. here we report the identification of four second-order raman modes, named d1, d1', d2 and d2', in e ... | 2018 | 29320856 |
high-co2 requirement as a mechanism for the containment of genetically modified cyanobacteria. | as researchers engineer cyanobacteria for biotechnological applications, we must consider potential environmental release of these organisms. previous theoretical work has considered cyanobacterial containment through elimination of the co2-concentrating mechanism (ccm) to impose a high-co2 requirement (hcr), which could be provided in the cultivation environment but not in the surroundings. in this work, we experimentally implemented an hcr containment mechanism in synechococcus sp. pcc7002 (pc ... | 2018 | 29320853 |
antioxidant and anti-freezing peptides from salmon collagen hydrolysate prepared by bacterial extracellular protease. | extracted salmon skin collagen was hydrolysed with the free or immobilized extracellular protease of vibrio sp. sqs2-3. the hydrolysate exhibited anti-freezing activity (>3 kda) and antioxidant activity (<3000 da) after ultrafiltration. the antioxidant peptide was further purified by size-exclusion chromatography and found to scavenge dpph (73.29 ± 1.03%), oh (72.73 ± 3.34%,), and intracellular ros in huvecs; protect dna against oxidation-induced damage; and have an orac of 2.78 ± 0.28 mmol te/g ... | 2018 | 29329864 |
the effect of continuous positive airway pressure on spectral encephalogram characteristics in stroke patients with obstructive sleep apnea. | to evaluate if treatment with continuous positive airway pressure (cpap) compared to usual care in stroke patients with obstructive sleep apnea (osa) over one month reduces delta and alpha oscillations on quantitative electroencephalography (eeg) in association with improvements in cognitive or functional outcomes. | 2018 | 29329819 |
nanobiostructure of fibrous-like alumina functionalized with an analog of the bp100 peptide: synthesis, characterization and biological applications. | the functionalization of alumina nanoparticles of specific morphology with antimicrobial peptides (amp) can be a promising strategy for modeling medical devices and packaging materials for cosmetics, medicines or food, since the contamination by pathogens could be reduced. in this paper, we show the synthesis of a fibrous-like alumina nanobiostructure, as well as its functionalization with the peptide eaaa-bp100, an analog of the antimicrobial peptide bp100. the antibacterial activity of the obt ... | 2018 | 29329073 |
association of comorbid personality disorders with clinical characteristics and outcome in a randomized controlled trial comparing two psychotherapies for early-onset persistent depressive disorder. | persistent depressive disorder (pdd) is associated with high rates of comorbid personality disorders (pd). the association of comorbid pd and clinical characteristics has not been systematically studied in pdd. results regarding effects on treatment outcome are heterogeneous. | 2018 | 29329058 |
cantilever nanobiosensor using tyrosinase to detect atrazine in liquid medium. | the aim of this study was to develop a cantilever nanobiosensor for atrazine detection in liquid medium by immobilising the biological recognition element (tyrosinase vegetal extract) on its surface with self-assembled monolayers using gold, 16-mercaptohexadecanoic acid, 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride/n-hydroxysuccinimide. cantilever nanobiosensors presented a surface compression tension increase when atrazine concentrations were increased, with a limit of detection ... | 2018 | 29319411 |
ruthenium(ii)-catalyzed c-h (hetero)arylation of alkenylic 1,n-diazines (n = 2, 3, and 4): scope, mechanism, and application in tandem hydrogenations. | a general ruthenium(ii)-catalyzed methodology enabling the (hetero)arylation of alkenylic c-h bonds utilizing a series of synthetically appealing diazines as directing groups is presented. despite the presence of additional nitrogen lone pairs remote from the c-h bond activation site, which could eventually poison the catalyst, the reaction times are short (3 h), thus being suitable for selective double c-h bond arylation. mixtures of e:z isomeric products were observed in some cases, which were ... | 2018 | 29319315 |
drug-induced micelle-to-vesicle transition of a cationic gemini surfactant: potential applications in drug delivery. | the impetus for the sustained interest in the formation of vesicles is their potential application as efficient drug delivery systems. a simple approach for ionic surfactants is to add a vesicle-inducing drug of opposite charge. in ionic gemini surfactants (gs) two molecules are covalently linked with a "spacer". considering drug-delivery, gs are more attractive candidates than their single-chain counterparts because of their high surface activity and the effect on the physico-chemical propertie ... | 2018 | 29319220 |
shape dependent physical mutilation and lethal effects of silver nanoparticles on bacteria. | in this report, spherical silver nanoparticle (agnp-sp) and rod-shaped silver nanoparticle (agnr) were prepared by chemical reduction method and their antibacterial activity against various gram-positive and gram-negative bacteria had been evaluated for their efficiency. minimal inhibitory concentration (mic) tests were conducted to study the antibacterial properties, and substantiated with killing kinetics of silver nanoparticles (agnps). the study revealed that both agnp-sp and agnrs are good ... | 2018 | 29317760 |
microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases. | the recently discovered histone post-translational modification crotonylation connects cellular metabolism to gene regulation. its regulation and tissue-specific functions are poorly understood. we characterize histone crotonylation in intestinal epithelia and find that histone h3 crotonylation at lysine 18 is a surprisingly abundant modification in the small intestine crypt and colon, and is linked to gene regulation. we show that this modification is highly dynamic and regulated during the cel ... | 2018 | 29317660 |
baroreflex stimulation attenuates central but not peripheral inflammation in conscious endotoxemic rats. | we previously reported that activation of the baroreflex, a critical physiological mechanism controlling cardiovascular homeostasis, through electrical stimulation of the aortic depressor nerve attenuates joint inflammation in experimental arthritis. however, it is unknown whether baroreflex activation can control systemic inflammation. here, we investigate whether baroreflex activation controls systemic inflammation in conscious endotoxemic rats. animals underwent sham or electrical aortic depr ... | 2018 | 29317289 |
nandrolone combined with strenuous resistance training reduces vascular nitric oxide bioavailability and impairs endothelium-dependent vasodilation. | anabolic androgenic steroids (aass) misuse has increased among adolescents and recreational athletes due to their potential effects on muscle hypertrophy. on the other hand, aas might induce alterations on cardiovascular system, although some controversies regarding aas on vascular properties remain unknown. to address this question, we aimed to investigate the effects of high doses of nandrolone combined with strenuous resistance training (rt) on function and structure of thoracic aorta. rats w ... | 2018 | 29317256 |
influence of artemisia annua l. on toll-like receptor expression in brain of mice infected with acanthamoeba sp. | the treatment of acanthamoebiasis is a still a problem. our previous studies showed that the application of extracts from artemisia annua l. significantly prolonged the survival of mice infected by acanthamoeba. this plant has medicinal properties in the treatment of human parasitic diseases. the aim of this study was to evaluate the effects of a. annua on expression of toll-like receptors (tlrs) 2 and 4 in brain of mice with acanthamoeba infection. mice were infected with acanthamoeba sp. strai ... | 2018 | 29317241 |
molecular identification of blastocystis sp. subtypes in water samples collected from black sea, turkey. | the aim of this study was to identify the subtypes of blastocystis sp. and complete a phylogenetic analysis of 268 water samples that were collected from the samsun, amasya and sinop provinces of the black sea in turkey, between the years 2011 and 2014. blastocystis sp. was investigated in 48 uncultured sea water samples that were collected from 4 sites within the sinop province. a total of 100 river water samples were collected from 37 sites in the samsun province and 120 river water samples we ... | 2018 | 29317171 |
[reversal of neuromuscular block with sugammadex in five heart transplant pediatric recipients]. | heart transplantation is a frequent procedure in the treatment of end-stage cardiac dysfunction. therefore, these patient populations will also be more frequent exposed to other more common surgical procedures after their transplantation. anesthesiologist should be aware in their assessment of these patients, especially regarding some specific issues related to patients with a history of heart transplantation, like reversal of neuromuscular block. several reports described that cholinesterase in ... | 2018 | 29317084 |
dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface-the protective role for bdnf. | the consumption of large amounts of dietary fats activates an inflammatory response in the hypothalamus, damaging key neurons involved in the regulation of caloric intake and energy expenditure. it is currently unknown why the mediobasal hypothalamus is the main target of diet-induced brain inflammation. we hypothesized that dietary fats can damage the median eminence blood/spinal fluid interface. | 2018 | 29316939 |
molecular identification of sulfadoxine-pyrimethamine resistance in malaria infected women who received intermittent preventive treatment in the democratic republic of congo. | point mutations in plasmodium falciparum dihydrofolate reductase (pfdhfr) and dihydropteroate synthase (pfdhps) genes which confer resistance to sulfadoxine-pyrimethamine (sp) occur at increasing rates. the present study aimed to identify pfdhfr and pfdhps mutations in p. falciparum isolates recovered from women who received two doses of sp during pregnancy in bandundu, the democratic republic of congo (drc). | 2018 | 29316929 |
risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. | glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (pmr) and giant cell arteritis (gca). however, fracture risk in these conditions has not been previously quantified. the aim of this study was to quantify the risk of fracture among patients with pmr and gca. | 2018 | 29316928 |
comparative assessment of probiotics and monensin in the prophylaxis of acute ruminal lactic acidosis in sheep. | acute ruminal lactic acidosis (arla) is a major nutritional and metabolic disorder usually characterized by excessive or non-adapted intake of diets rich in nonstructural carbohydrates. feed additives that regulate the ruminal environment have been used to prevent arla, such as ionophores and, more recently, yeast culture. thus, we aimed to compare the efficacy of a yeast-based culture (saccharomyces cerevisiae) with that of monensin sodium in the prevention of arla in sheep. eighteen male, cros ... | 2018 | 29316923 |
in silico epitope mapping and experimental evaluation of the merozoite adhesive erythrocytic binding protein (maebl) as a malaria vaccine candidate. | technical limitations for culturing the human malaria parasite plasmodium vivax have impaired the discovery of vaccine candidates, challenging the malaria eradication agenda. the immunogenicity of the m2 domain of the merozoite adhesive erythrocytic binding protein (maebl) antigen cloned from the plasmodium yoelii murine parasite, has been previously demonstrated. | 2018 | 29316918 |
flocculation effect of alkaline electrolyzed water(aew) on harvesting of marine microalgae tetraselmis sp. | microalgae hold promise as a renewable energy source for the production of biofuel, as they can convert light energy into chemical energy through photosynthesis. however, cost-efficient harvest of microalgae remains a major challenge to commercial-scale algal biofuel production. we firstly investigated the potential of electrolytic water as a flocculantfor harvesting tetraselmis sp.alkaline electrolytic water (aew) is produced at cathode through water electrolysis.it contains mineral ions such a ... | 2018 | 29316738 |
novel synthesis of slightly fluorinated graphene quantum dots with luminescent and paramagnetic properties through thermal cutting of fluorinated graphene. | a novel approach has been developed to synthesize slightly fluorinated graphene quantum dots (gqds-f) through thermal cutting of highly fluorinated graphene. the fluorinated graphene with substantial structure defects is fragile and is readily attacked. the direct evaporation of abundant cfn (n = 2, 3) groups near structure defects lead to the loss of adjacent skelton c atoms, and the fluorinated graphene can be thermally cut into gqds-f with a relatively uniform nanosize in pyrolysis at 810 k. ... | 2018 | 29316730 |
chemical characterization of a renoprotective metabolite from termite-associated streptomyces sp. rb1 against cisplatin-induced cytotoxicity. | platinum-based anticancer drug therapies can cause renal damage and apoptotic kidney cell damage. the development of reno- and kidney-protective molecules is therefore urgently required. to address this challenge, we explored secondary metabolites of termite-associated streptomyces sp. rb1 isolated from the cuticle of the south african termite, macrotermes natalensis for their renoprotective ability using bioassay-guided fractionation and llc-pk1 cells. chemical investigation of the meoh extract ... | 2018 | 29316657 |
effects of early neglect experience on recognition and processing of facial expressions: a systematic review. | background: child neglect is highly prevalent and associated with a series of biological and social consequences. early neglect may alter the recognition of emotional faces, but its precise impact remains unclear. we aim to review and analyze data from recent literature about recognition and processing of facial expressions in individuals with history of childhood neglect. methods: we conducted a systematic review using pubmed, psycinfo, scielo and embase databases in the search of studies for t ... | 2018 | 29316648 |
enlarged basal ganglia perivascular spaces are associated with pulsatile components of blood pressure. | pathogenetic mechanisms involved in enlargement of basal ganglia perivascular spaces (bg-pvss) are controversial. here, we assessed whether pulsatile or steady components of blood pressure (bp) are associated with enlarged bg-pvs. | 2018 | 29316559 |
discovery of potent and orally bioavailable dihydropyrazole gpr40 agonists. | g protein-coupled receptor 40 (gpr40) has become an attractive target for the treatment of diabetes since it was shown clinically to promote glucose-stimulated insulin secretion. herein, we report our efforts to develop highly selective and potent gpr40 agonists with a dual mechanism of action, promoting both glucose-dependent insulin and incretin secretion. employing strategies to increase polarity and the ratio of sp3/sp2 character of the chemotype, we identified bms-986118 (compound 4), which ... | 2018 | 29316397 |
fully anharmonic vibrational resonance raman spectrum of diatomic systems. | a study is presented on the resonance raman (rr) spectrum based on fully anharmonic wave functions and energies obtained from ab initio multireference potential energy curves of diatomic systems. the vibrational problem is numerically solved using a variational stochastic method or the cooley-numerov method, as implemented in le roy's level program. anharmonic franck-condon and herzberg-teller integrals are numerically evaluated, and the rr polarizability is calculated within the time-independen ... | 2018 | 29316391 |
protein profile in aspergillus nidulans recombinant strains overproducing heterologous enzymes. | filamentous fungi are robust cell factories and have been used for the production of large quantities of industrially relevant enzymes. however, the production levels of heterologous proteins still need to be improved. therefore, this article aimed to investigate the global proteome profiling of aspergillus nidulans recombinant strains in order to understand the bottlenecks of heterologous enzymes production. about 250, 441 and 424 intracellular proteins were identified in the control strain ani ... | 2018 | 29316319 |
probiotic lactobacillus sp. inhibit growth, biofilm formation and gene expression of caries-inducing streptococcus mutans. | streptococcus mutans contributes significantly to dental caries, which arises from homoeostasic imbalance between host and microbiota. we hypothesized that lactobacillus sp. inhibits growth, biofilm formation and gene expression of streptococcus mutans. antibacterial (agar diffusion method) and antibiofilm (crystal violet assay) characteristics of probiotic lactobacillus sp. against streptococcus mutans (atcc 25175) were evaluated. we investigated whether lactobacillus casei (atcc 393), lactobac ... | 2018 | 29316223 |
cellular stress induces cancer stem-like cells through expression of dnajb8 by activation of hsf1. | in a previous study, we found that dnajb8, a heat shock protein (hsp) 40 family member is expressed in kidney cancer stem-like cells (cscs)/cancer-initiating cells (cics) and that it has a role in the maintenance of kidney cscs/cics. heat shock factor (hsf) 1 is a key transcription factor for responses to stress including heat shock, and it induces hsp family expression through activation by phosphorylation. in this study, we therefore examined whether heat shock (hs) induces cscs/cics. we treat ... | 2018 | 29316077 |
effect of euk-134 on akt-mtor signaling in the rat soleus during 7 days of mechanical unloading. | mechanical unloading stimulates rapid changes in skeletal muscle morphology, characterized by atrophy of muscle fiber cross-sectional area (csa) and a partial fiber-type shift from slow to fast-twitch. recent studies revealed that oxidative stress contributes to activation of foxo3a, proteolytic signaling and unloading-induced muscle atrophy via translocation of the mu-splice variant of neuronal nitric oxide synthase (nnosμ) and activation of foxo3a. yet, there is limited understanding of the ro ... | 2018 | 29315934 |
does the choice of the crystal structure influence the results of the periodic dft calculations? a case of glycine alpha polymorph gipaw nmr parameters computations. | glycine is a common amino acid with relatively complex chemistry in solid state. although several polymorphs (α, β, δ, γ, ε) of crystalline glycine are known, for nmr spectroscopy the most important is a polymorph, which is used as a standard for calibration of spectrometer performance and therefore it is intensively studied by both experimental methods and theoretical computation. the great scientific interest in a glycine results in a large number of crystallographic information files (cifs) d ... | 2018 | 29315751 |
errata of candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a japanese hospital. | candida auris, which we described in 2009 (1), has become a global health threat (2). due to the increasing interest in c. auris, we have received a number of questions regarding this topic. on re-examining the data to respond to these queries, a single important error was found in our manuscript. therefore, we have issued an erratum. | 2018 | 29315744 |
fractional excretion of urea: a simple tool for the differential diagnosis of acute kidney injury in cirrhosis. | current approaches to determine the cause of acute kidney injury (aki) in patients with cirrhosis are suboptimal. the aim of this study was to determine the utility of fractional excretion of urea (feurea) for the differential diagnosis of aki in cirrhotic patients. a retrospective analysis was performed in patients (n=50) with cirrhosis and ascites admitted with aki. using adjudicated etiology assessment as the reference standard, receiver operating curves (roc) and optimal cutoff, sensitivity ... | 2018 | 29315697 |
suppression of a single bahd gene in setaria viridis causes large, stable decreases in cell wall feruloylation and increases biomass digestibility. | feruloylation of arabinoxylan (ax) in grass cell walls is a key determinant of recalcitrance to enzyme attack, making it a target for improvement of grass crops, and of interest in grass evolution. definitive evidence on the genes responsible is lacking so we studied a candidate gene that we identified within the bahd acyl-coa transferase family. we used rna interference (rnai) silencing of orthologs in the model grasses setaria viridis (svbahd01) and brachypodium distachyon (bdbahd01) and deter ... | 2018 | 29315591 |
comparisons of electron transfer reactions in a cyanobacterial tetrameric and trimeric photosystem i complexes. | photosystem i (psi) is a type-i reaction center and the largest photosynthetic complex to be characterized. in cyanobacteria, psi is organized as a trimer with a three-fold axis of symmetry. recently, a tetrameric form of psi has been identified in cyanobacteria. plastids in plants and algae only contain monomeric psi, suggesting that tetrameric psi may be key in the transition from ancestral cyanobacterial trimeric psi to plant/algal monomeric psi. we have investigated the kinetics of e- transf ... | 2018 | 29315587 |
isoaaptamine induces t-47d cells apoptosis and autophagy via oxidative stress. | aaptos is a genus of marine sponge which belongs to suberitidae and is distributed in tropical and subtropical oceans. bioactivity-guided fractionation of aaptos sp. methanolic extract resulted in the isolation of aaptamine, demethyloxyaaptamine, and isoaaptamine. the cytotoxic activity of the isolated compounds was evaluated revealing that isoaaptamine exhibited potent cytotoxic activity against breast cancer t-47d cells. in a concentration-dependent manner, isoaaptamine inhibited the growth of ... | 2018 | 29315210 |
the bioactive extract of pinnigorgia sp. induces apoptosis of hepatic stellate cells via ros-erk/jnk-caspase-3 signaling. | the activation of hepatic stellate cells (hscs) is a significant phenomenon during the pathogenesis of liver disorders, including liver cirrhosis and fibrosis. here, we identified that the extract from a gorgonian coral pinnigorgia sp. (pin) induced apoptosis of hsc-t6 cells. pin inhibited the viability of hsc-t6 cells and increased their subg1 population, dna fragmentation, caspase-3 activation, and reactive oxygen species (ros) production in a concentration-dependent manner. the pin-induced ro ... | 2018 | 29315209 |
prolinimines: n-amino-l-pro-methyl ester (hydrazine) schiff bases from a fish gastrointestinal tract-derived fungus, trichoderma sp. cmb-f563. | a rice cultivation of a fish gastrointestinal tract-derived fungus, trichoderma sp. cmb-f563, yielded natural products incorporating a rare hydrazine moiety, embedded within a schiff base. structures inclusive of absolute configurations were assigned to prolinimines a-d (1-4) on the basis of detailed spectroscopic and c3 marfey's analysis, as well as biosynthetic considerations, biomimetic total synthesis, and chemical transformations. of note, monomeric 1 proved to be acid labile and, during is ... | 2018 | 29314856 |
gpsit: an automated method for evolutionary analysis of nonculturable ciliated microeukaryotes. | microeukaryotes are among the most important components of the microbial food web in almost all aquatic and terrestrial ecosystems worldwide. in order to gain a better understanding their roles and functions in ecosystems, sequencing coupled with phylogenomic analyses of entire genomes or transcriptomes are increasingly used to reconstruct the evolutionary history and classification of these microeukaryotes and thus provide a more robust framework for determining their systematics and diversity. ... | 2018 | 29314766 |
molecular processes underlying synergistic linuron mineralization in a triple-species bacterial consortium biofilm revealed by differential transcriptomics. | the proteobacteria variovorax sp. wdl1, comamonas testosteroni wdl7, and hyphomicrobium sulfonivorans wdl6 compose a triple-species consortium that synergistically degrades and grows on the phenylurea herbicide linuron. to acquire a better insight into the interactions between the consortium members and the underlying molecular mechanisms, we compared the transcriptomes of the key biodegrading strains wdl7 and wdl1 grown as biofilms in either isolation or consortium conditions by differential rn ... | 2018 | 29314727 |
novel large-pore lightweight polypropylene mesh has better biocompatibility for rat model of hernia. | abdominal wall hernias are repaired with tension-free prosthetic materials but there remains a foreign body response (fbr) to commonly used polypropylene mesh. thus, we should optimize mesh materials to improve the patient outcomes after surgery. a polypropylene mesh was developed with wrap knitting technique. the physical, mechanical and biocompatible characteristics were tested in a rat abdominal hernia model and compared to ultrapro and easy prosthesis. polypropylene mesh of two pore sizes wa ... | 2018 | 29314586 |
polyhydroxyalkanoates (pha) production in bacterial co-culture using glucose and volatile fatty acids as carbon source. | mixed bacterial cultures are increasingly being used in the production of polyhydroxyalkanoates (phas), as they have the potential to be more cost effective than axenic pure cultures. the purpose of this study was to use pure cultures in combination to identify their potential of pha production. in this work we used volatile fatty acids (vfas) and glucose as carbon source to check the ability of selected strains st2 (pseudomonas sp.) and cs8 (bacillus sp.) as co-culture. the production of pha in ... | 2018 | 29314110 |
semiclassical transport properties of irga<sub>3</sub>: a promising thermoelectric material. | irga3 is an intermetallic compound which is expected to be a metal, but a study on the electronic properties of this material to confirm its metallic character is not available in the literature. in this work, we report for the first time a first-principles density functional theory and semiclassical boltzmann theory study of the structural, electronic and transport properties of this material. the inclusion of the spin-orbit coupling term is crucial to calculate accurately the electronic proper ... | 2018 | 29313827 |
metal-free one-pot synthesis of 3-phosphinoylbenzofurans via phospha-michael addition/cyclization of h-phosphine oxides and in situ generated ortho-quinone methides. | a novel metal-free one-pot protocol for the effective and efficient synthesis of 3-phosphinoylbenzofurans via a phospha-michael addition/cyclization of h-phosphine oxides and in situ generated ortho-quinone methides is described. based on the expeditious construction of c(sp2)-p bonds, asymmetric synthesis of optically pure 3-phosphinoylbenzofurans containing chiral p-stereogenic center has also been probed by using chiral rp-(-)-menthyl phenylphosphine oxide. | 2018 | 29313691 |
adsorption of dicamba herbicide onto a carbon replica obtained from a layered double hydroxide. | in this work, a carbon replica derived from a vinylbenzenesulfonate-intercalated layered double hydroxide (cr-ldh) was applied to remove the dicamba organochlorine herbicide from aqueous solution. the samples were characterized by several experimental techniques such as x-ray diffraction (xrd), thermogravimetric analysis coupled with differential scanning calorimetry and mass spectrometry (tga-dsc-ms), x-ray photoelectron spectroscopy (xps), scanning electron microscopy (sem), raman spectroscopy ... | 2018 | 29313540 |
microcystin-lr degradation utilizing a novel effective indigenous bacterial community yfmcd1 from lake taihu. | microcystins (mc) produced by species of cyanobacteria including microcystis, anabaena, and aphanizomenon are a group of monocyclic hepatotoxins posing serious threat to public health. microcystin-lr (mc-lr) is the most toxic and frequently encountered microcystin variant in the environment, and thus removal of this toxin using bacteria was shown to be a reliable, efficient, and cost-effective method that avoids utilization of chemicals that may produce potentially harmful by-products. the aim o ... | 2018 | 29313451 |
biosynthesis of silver nanoparticles using novel bacillus sp. sbt8. | biosynthesis of silver nanoparticles (agnps) using microorganisms is an important application of nano-biotechnology and green chemistry because of interest by pharmaceutical and food manufacturers. in this study, biosynthesis of agnps by a novel bacillus strain isolated from a soil sample from sakarya district in turkey was investigated. biosynthesis was performed using cell-free supernatant of the bacterium following 24 h growth. effects of varying agno3 concentration (1-10 mm), ph (5-10), and ... | 2018 | 29313428 |
protuboxepin c and protuboxepin d from the sponge-derived fungus aspergillus sp scsio xws02f40. | two new diketopiperazine alkaloids, named protuboxepin c (1) and protuboxepin d (2), which contain d-phe residue and oxepin ring, were isolated from etoac extract of sponge-derived fungus aspergillus sp scsio xws02f40. their structures were elucidated by 1d, 2d nmr and hresims dates, and their absolute configurations were confirmed by single crystal x-ray diffraction experiments and cd analyses. the in vitro cytotoxicity of these two new compounds was further evaluated using a549 and hela cell l ... | 2018 | 29313378 |
theoretical study of the effects of substituents (f, cl, br, ch3, and cn) on the aromaticity of borazine. | this paper presents a theoretical study of the effects of substituents (f, cl, br, ch3, and cn) on the aromaticity of borazine (b3n3h6), using density functional theory (dft) and the hartree-fock (hf) method. the calculations to optimize the geometries, structural properties, and vibrational frequencies were performed using the same 6-311g(d,p) and 6-311++g(d,p) basis sets, comparing the methods with experimental results. in the analysis of the nicszz values, it was found that that replacing the ... | 2018 | 29313144 |
photoacidity as a tool to rationalize excited state intramolecular proton transfer reactivity in flavonols. | this work presents the determination of acidic strengths at the electronic ground and excited states (pka and ) of three flavonol derivatives using electronic absorption and fluorescence emission spectroscopy. the differences of the pka and values were successfully correlated with the molecular structures according to the substitution pattern at the flavonol structure (hydrogen, diethylamino or fluoro moieties). in order to obtain more information about the observed photoacidity of these superac ... | 2018 | 29313047 |
fluorescent imaging analysis for distribution of fluorescent dye labeled- or encapsulated- liposome in monocrotaline-induced pulmonary hypertension model rat. | pulmonary hypertension (ph) is a life-threatening lung disease. despite the availability of several approved drugs, the development of a new treatment method is needed because of poor prognosis. tissue selective drug delivery systems can avoid the adverse effects of current therapy and enhance efficacy. we evaluated the possibility of delivering drugs to the lungs of a ph rat model using fluorescence dye-labeled nanosized liposomes. to evaluate the tissue distribution following systemic exposure ... | 2018 | 29311495 |
high prevalence of hepatitis b subgenotype d4 in northeast brazil: an ancient relic from african continent? | hepatitis b virus (hbv) infection leads to a chronic liver disease that is distributed worldwide. the characterization of hbv into genotypes/subgenotypes is not only a mere procedure for distinguishing different hbv strains around the world because determining their geographic distribution is crucial to understanding their spread across the world. | 2018 | 29311410 |
immobilization of β-1,3-1,4-glucanase from bacillus sp. on porous silica for production of β-glucooligosaccharides. | (1,3)(1,4)-β-d-glucan has been determined to have various beneficial effects due to its unique structure. β-glucooligosaccharides (β-gos), which are hydrolysates of barley (1,3)(1,4)-β-d-glucan, provide a useful prebiotic material for selective growth of probiotic bacteria. in this study, recombinant β-1,3-1,4-glucanase (bg1314) from bacillus sp. sj-10 (kccm 90078) was immobilized on porous silica using glutaraldehyde as a crosslinking reagent to achieve efficient production of β-gos. we investi ... | 2018 | 29310853 |
[sedation using dexmedetomidine and remifentanil with local anesthesia for intraoperative speech monitoring: a case report]. | some surgical procedures such as laryngoplasty require patients to remain conscious during the intraoperative phase in order to enable speech monitoring. dexmedetomidine and remifentanil were used in this study, since they promote appropriate patient collaboration with facilitated awakening, and are rapidly eliminated. | 2018 | 29310828 |
photobiomodulation using low-level laser therapy (lllt) for patients with chronic traumatic brain injury: a randomized controlled trial study protocol. | photobiomodulation using low-level laser therapy (lllt) has been tested as a new technique to optimize recovery of patients with traumatic brain injury (tbi). the aim of this study is to evaluate inhibitory attentional control after 18 sessions of active lllt and compare with the placebo group (sham lllt). our exploratory analysis will evaluate the efficacy of the active lllt on verbal and visuospatial episodic memory, executive functions (working memory, verbal and visuospatial fluency, attenti ... | 2018 | 29310710 |
correction to: towards a consensus definition of maternal sepsis: results of a systematic review and expert consultation. | after publication of the original article [1], it came to the authors' attention that the acknowledgements section was not completed correctly. the acknowledgements of the article should have been as follows. | 2018 | 29310684 |
failure to shorten the diagnostic delay in two ultra-orphan diseases (mucopolysaccharidosis types i and iii): potential causes and implications. | rare diseases are often un- or misdiagnosed for extended periods, resulting in a long diagnostic delay that may significantly add to the burden of the disease. an early diagnosis is particularly essential if a disease-modifying treatment is available. the purpose of this study was to assess the extent of the diagnostic delay in the two ultra-rare diseases, i.e., mucopolysaccharidosis i (mps i) and iii (mps iii), both of which are lysosomal storage disorders with different phenotypic severities ( ... | 2018 | 29310675 |
simultaneous determination of six quality parameters of biodiesel through 1h nmr spectroscopy and partial least squares. | biodiesel quality is checked by determining several parameters. considering the large number of analyses in this verification, as well as the disadvantages of the use of toxic solvents and waste generation, multivariate calibration is suggested to reduce the number of tests. in this work, hydrogen nuclear magnetic resonance (1h nmr) spectra were used to build multivariate models, from partial least squares (pls), in order to perform simultaneous determination of six important quality parameters ... | 2018 | 29310312 |
a simple and fast method to determine water content in biodiesel by electrochemical impedance spectroscopy. | in this paper, a fast, simple and new alternative method for determination of water content (moisture) in biodiesel using electrochemical impedance spectroscopy (eis) is developed. the method is based on the sensitive variation of the charge transfer resistance (rct) of the biodiesel medium in the presence of different quantities of water. to obtain an accurate analytical measurement, a pre-treatment based on a simple dilution by acetonitrile is employed. the two identical pt electrodes are used ... | 2018 | 29310304 |
cai and sri molecules for iodine determination by high-resolution continuum source graphite furnace molecular absorption spectrometry: greener molecules for practical application. | a new method to determine iodine in drug samples by high-resolution continuum source graphite furnace molecular absorption spectrometry (hr-cs gf mas) has been developed. the method measures the molecular absorption of a diatomic molecule, cai or sri (less toxic molecule-forming reagents), at 638.904 or 677.692nm, respectively, and uses a mixture containing 5μg of pd and 0.5μg of mg as chemical modifier. the method employs pyrolysis temperatures of 1000 and 800°c and vaporization temperatures of ... | 2018 | 29310275 |
gold leaf: from gilding to the fabrication of disposable, wearable and low-cost electrodes. | gold is among the most used materials in electrocatalysis. despite this, this noble metal is still too expensive to be used in the fabrication of low cost and disposable devices. in the present work, gold-leaf sheets, usually employed in decorative crafts and wedding candies, is introduced as an inexpensive source of gold. planar-disc and nanoband gold electrodes were simply and easily manufactured by combining gold leaf and polyimide tape. the planar disc electrode exhibited electrochemical beh ... | 2018 | 29310267 |
real-time monitoring of a coffee roasting process with near infrared spectroscopy using multivariate statistical analysis: a feasibility study. | this work proposes the use of near infrared (nir) spectroscopy in diffuse reflectance mode and multivariate statistical process control (mspc) based on principal component analysis (pca) for real-time monitoring of the coffee roasting process. the main objective was the development of a mspc methodology able to early detect disturbances to the roasting process resourcing to real-time acquisition of nir spectra. a total of fifteen roasting batches were defined according to an experimental design ... | 2018 | 29310234 |
exploiting multivariate calibration for compensation of iron interference in the spectrophotometric flow-based catalytic determination of molybdenum. | multivariate calibration involving partial least squares was exploited in the flow-based spectrophotometric determination of molybdenum in river waters relying on the mo(vi)-catalyzed iodide oxidation by h2o2 under acidic conditions. two sample aliquots were simultaneously inserted into the carrier stream, and differential pumping was accountable for in-line addition of sulfuric acid to one of them. pronounced gradients (acidity and reagent concentrations) were established along the complex samp ... | 2018 | 29310215 |
a new and simple method for the simultaneous determination of amoxicillin and nimesulide using carbon black within a dihexadecylphosphate film as electrochemical sensor. | the first electroanalytical method for the simultaneous determination of an important antibiotic (amoxicillin - amx) and an anti-inflammatory drug (nimesulide -nim), widely used in combination, is here proposed. in this method, a glassy carbon (gc) substrate modified with carbon black (cb) immobilized within a dihexadecylphosphate (dhp) film is used as electrochemical sensor (cb-dhp/gc). the electrochemical activity of this sensor was assessed (comparatively to that of gc) by electrochemical imp ... | 2018 | 29310210 |
targeting cytokines in reduction of depressive symptoms: a comprehensive review. | heterogeneity in response to conventional antidepressants is a well-recognized limitation of evidence-based pharmacological treatments of major depressive disorder (mdd). abnormal activation of inflammatory pathways is postulated as one likely mechanism contributing to treatment resistance in mdd. in a subset of depressed patients, the balance between pro- and anti-inflammatory cytokines is thought to be altered, causing mood symptoms due to inflammation, as seen in co-morbid depression associat ... | 2018 | 29309829 |
combinations of laxatives and green banana biomass on the treatment of functional constipation in children and adolescents: a randomized study. | evaluate the effect of combinations of green banana biomass and laxatives in children and adolescents with chronic constipation. | 2018 | 29309737 |
impaired systemic oxygen extraction in treated exercise pulmonary hypertension: a new engine in an old car? | ambrisentan in 22 patients with pulmonary hypertension diagnosed during exercise (eph) improved pulmonary hemodynamics; however, there was only a trend toward increased maximum oxygen uptake (vo2max) secondary to decreased maximum exercise systemic oxygen extraction (ca-vo2). we speculate that improved pulmonary hemodynamics at maximum exercise "unmasked" a pre-existing skeletal muscle abnormality. | 2018 | 29309261 |
proanthocyanidin polymeric tannins from stryphnodendron adstringens are effective against fluconazole-resistant candida spp. and treat vaginal candidiasis. | the stem bark of stryphnodendron adstringens (mart.) coville is popularly used as anti-inflammatory, astringent and in the treatment of wounds and vaginal infections. several pharmacological activities have been scientifically proven by "in vitro" and "in vivo" experimental assays for antibacterial, antiviral, antiprotozoan, anti-inflammatory and antioxidant. | 2018 | 29325916 |
impact of the childhood vaccine discussion format over time on immunization status. | presumptive formats to initiate childhood vaccine discussions (e.g. "well we have to do some shots.") have been associated with increased vaccine acceptance after one visit compared to participatory formats (e.g. "how do you feel about vaccines?"). we characterize discussion format patterns over time and the impact of their repeated use on vaccine acceptance. | 2018 | 29325912 |