Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| a single oral administration of theaflavins increases energy expenditure and the expression of metabolic genes. | theaflavins are polyphenols found in black tea, whose physiological activities are not well understood. this study on mice evaluated the influence of a single oral administration of theaflavins on energy metabolism by monitoring the initial metabolic changess in skeletal muscle and brown adipose tissue (bat). oxygen consumption (vo2) and energy expenditure (ee) were increased significantly in mice treated with theaflavin rich fraction (tf) compared with the group administered vehicle alone. ther ... | 2015 | 26375960 |
| pyrrolizidine alkaloids in food and feed on the belgian market. | pyrrolizidine alkaloids (pas) are widely distributed plant toxins with species dependent hepatotoxic, carcinogenic, genotoxic and pneumotoxic risks. in a recent european food safety authority (efsa) opinion, only two data sets from one european country were received for honey, while one feed data set was included. no data are available for food or feed samples from the belgian market. we developed an lc-ms/ms method, which allowed the detection and quantification of 16 pas in a broad range of ma ... | 2015 | 26373269 |
| transcriptome analysis reveals key flavonoid 3'-hydroxylase and flavonoid 3',5'-hydroxylase genes in affecting the ratio of dihydroxylated to trihydroxylated catechins in camellia sinensis. | the ratio of dihydroxylated to trihydroxylated catechins (rdtc) is an important indicator of tea quality and biochemical marker for the study of genetic diversity. it is reported to be under genetic control but the underlying mechanism is not well understood. flavonoid 3'-hydroxylase (f3'h) and flavonoid 3',5'-hydroxylase (f3'5'h) are key enzymes involved in the formation of dihydroxylated and trihydroxylated catechins. the transcriptome and hplc analysis of tea samples from longjing43 and zhong ... | 2015 | 26367395 |
| pyrrolizidine and tropane alkaloids in teas and the herbal teas peppermint, rooibos and chamomile in the israeli market. | dehydro pyrrolizidine alkaloids (dehydro pas) are carcinogenic phytotoxins prevalent in the boraginaceae, asteraceae and fabaceae families. dehydro pas enter the food and feed chain by co-harvesting of crops intended for human and animal consumption as well as by carry-over into animal-based products such as milk, eggs and honey. recently the occurrence of dehydro pas in teas and herbal teas has gained increasing attention from the eu, due to the high levels of dehydro pas found in commercially ... | 2015 | 26365752 |
| estimation of flavonoid intake in older australians: secondary data analysis of the blue mountains eye study. | flavonoids, consumed in plant-based foods, have been linked to risk reduction of cancers, cardiovascular, and neurodegenerative diseases. the paucity of information on dietary sources and quantities of flavonoid intake in older adults limits interpretation of epidemiological studies that link flavonoid intake with health outcomes in this population. it was our aim to describe total flavonoid intake, including flavonoid subclasses, in older australians and to identify rich and commonly consumed s ... | 2015 | 26571356 |
| regulation of formation of volatile compounds of tea (camellia sinensis) leaves by single light wavelength. | regulation of plant growth and development by light wavelength has been extensively studied. less attention has been paid to effect of light wavelength on formation of plant metabolites. the objective of this study was to investigate whether formation of volatiles in preharvest and postharvest tea (camellia sinensis) leaves can be regulated by light wavelength. in the present study, in contrast to the natural light or dark treatment, blue light (470 nm) and red light (660 nm) significantly incre ... | 2015 | 26567525 |
| [aging process of puer black tea studied by ftir spectroscopy combined with curve-fitting analysis]. | for better determination of the chemical components in the puer black tea, fourier transform infrared spectroscopy was used for obtaining vibrational spectra of puer black tea at different aging time. fourier transform infrared (ftir) spectra indicated that the chemical components had change in puer black tea at different aging time. the leaf of puer black tea was a complex system, its fourier transform infrared spectrum showed a total overlap of each absorption spectrum of various components. e ... | 2015 | 26717740 |
| antioxidant activity and phenolic content of leaf infusions of myrtaceae species from cerrado (brazilian savanna). | abstractthere is considerable interest in identifying new antioxidants from plant materials. several studies have emphasized the antioxidant activity of species belonging to the myrtaceae family. however, there are few reports on these species from the cerrado (brazilian savanna). in this study, the antioxidant activity and phenolic content of 12 native myrtaceae species from the cerrado were evaluated (blepharocalyx salicifolius, eugenia bimarginata, eugenia dysenterica, eugenia klotzschiana, h ... | 2015 | 26560669 |
| isolation and expression analysis of 18 csbzip genes implicated in abiotic stress responses in the tea plant (camellia sinensis). | basic leucine zipper (bzip) transcription factors (tfs) play essential roles in regulating stress processes in plants. despite the economic importance of this woody crop, there is little information about bzip tfs in tea plants. in this study, 18 bzip genes were isolated from the tea plant (camellia sinensis) and named sequentially from csbzip1 to csbzip18. according to the phylogenetic classification as in arabidopsis, the csbzip genes spanned ten subgroups (group a, b, c, d, e, f, h, i, s and ... | 2015 | 26555901 |
| topical lipophilic epigallocatechin-3-gallate on herpes labialis: a phase ii clinical trial of averteax formula. | previous in vitro and in vivo studies indicated that catechins from the tea plant (camellia sinensis) have a therapeutic effect on herpes simplex virus infections. the aim of this study was to clinically evaluate a topical proprietary formulation containing lipophilic catechins (averteax, camellix, llc, evans, ga, usa) on recurrent herpes labialis. | 2015 | 26548726 |
| genome-wide identification of genes probably relevant to the uniqueness of tea plant (camellia sinensis) and its cultivars. | tea (camellia sinensis) is a popular beverage all over the world and a number of studies have focused on the genetic uniqueness of tea and its cultivars. however, molecular mechanisms underlying these phenomena are largely undefined. in this report, based on expression data available from public databases, we performed a series of analyses to identify genes probably relevant to the uniqueness of c. sinensis and two of its cultivars (lj43 and zh2). evolutionary analyses showed that the evolutiona ... | 2015 | 26543846 |
| new sample preparation method for quantification of phenolic compounds of tea (camellia sinensis l. kuntze): a polyphenol rich plant. | chemical analysis of the sri lankan tea (camellia sinensis, l.) germplasm would immensely contribute to the success of the tea breeding programme. however, the polyphenols, particularly catechins (flavan-3-ols), are readily prone to oxidation in the conventional method of sample preparation. therefore, optimization of the present sample preparation methodology for the profiling of metabolites is much important. two sample preparation methodologies were compared, fresh leaves (as in the conventio ... | 2015 | 26543665 |
| cs-mir156 is involved in the nitrogen form regulation of catechins accumulation in tea plant (camellia sinensis l.). | the nitrogen source affects the growth of tea plants and regulates the accumulation of catechins in the leaves. in this report, we assessed the influences of nh4(+) and no3(-) on plant growth, catechins accumulation and associated gene expression. compared with the preferential nitrogen source nh4(+), when no3(-) was supplied as the sole nitrogen source, tea plants showed similar symptoms with the nitrogen-free treatments and showed lower nitrogen, free amino acid accumulation, chlorophyll conte ... | 2015 | 26520678 |
| analysis of stereochemistry and biosynthesis of epicatechin in tea plants by chiral phase high performance liquid chromatography. | tea (camellia sinensis) is rich in flavan-3-ols (catechins), especially epicatechin (ec), which is the predominant extension unit of polymeric proanthocyanidins (pas). however, studies assessing ec's stereochemistry are scarce. here, a high performance liquid chromatography column using amylose tris-(3, 5-dimethylphenylcarbamate) immobilized on silica-gel as chiral stationary phases (csps) was applied to explore its stereochemistry and biosynthetic pathway in tea plants. the results revealed (-) ... | 2015 | 26519617 |
| erratum: relationship between gene expression and the accumulation of catechin during spring and autumn in tea plants (camellia sinensis l.). | [this corrects the article doi: 10.1038/hortres.2015.11.][this corrects the article doi: 10.1038/hortres.2015.11.]. | 2015 | 26506527 |
| relationship between gene expression and the accumulation of catechin during spring and autumn in tea plants (camellia sinensis l.). | the tea plant (camellia sinensis l.) is an important commercial crop with remarkably high catechin concentrations. tea is popular worldwide given the plant's health benefits. catechins are the main astringent substance in tea and are synthesized mainly via the phenylpropanoid pathway. in this study, eight cultivars of tea plants harvested both in spring and autumn were used to investigate differences in catechin concentrations by using high-performance liquid chromatography. the expression level ... | 2015 | 26504566 |
| nontargeted analysis using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry uncovers the effects of harvest season on the metabolites and taste quality of tea (camellia sinensis l.). | the chemical composition and taste quality of tea fluctuate seasonally. however, the compounds responsible for the seasonal variation of metabolic pattern and taste quality are far from clear. this study compared the metabolite profiles of green teas of nine varieties that were plucked in spring, summer, and autumn by using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry (uplc-q-tof/ms) on a reversed phase column. a multivariate analysis indicated distinct diff ... | 2015 | 26494158 |
| molecular cloning and characterization of spermine synthesis gene associated with cold tolerance in tea plant (camellia sinensis). | spermine synthase (spms, ec 2.5.1.22), enzyme of spermine (spm) biosynthesis, has been shown to be related to stress response. in this study, attempts were made to clone and characterize a gene encoding spms from tea plant (camellia sinensis). the effect of exogenous application of spm in c. sinensis subjected to low-temperature stress was also investigated. a full-length spms complementary dna (cdna) (csspms) with an open reading frame of 1113 bp was cloned using reverse transcription-pcr and r ... | 2015 | 26276446 |
| a study on quality components and sleep-promoting effects of gaba black tea. | the aims of this study were to analyze the changes in quality components of gamma (γ)-aminobutyric acid (gaba) black tea during processing, and to investigate the effect of three dosages of gaba black tea on sleep improvement. the results showed that the gaba content was increased significantly up to 2.70 mg g(-1) after vacuum anaerobic and aerobic treatment. in addition, the content of gaba after drying reached 2.34 mg g(-1), which achieved the standard of gaba tea. during the entire processing ... | 2015 | 26290415 |
| effect of brewing duration on the antioxidant and hepatoprotective abilities of tea phenolic and alkaloid compounds in a t-bhp oxidative stress-induced rat hepatocyte model. | tea is an interesting source of antioxidants capable of counteracting the oxidative stress implicated in liver diseases. we investigated the impact of antioxidant molecules provided by a mixture of teas' leaves (green, oolong, pu-erh) after different infusion durations in the prevention of oxidative stress in isolated rat hepatocytes, by comparison with pure epigallocatechin-3-gallate (egcg), the main representative of tea catechins. dried aqueous tea extracts (ate) obtained after 5, 15 and 30 m ... | 2015 | 26287152 |
| pantoea theicola sp. nov., isolated from black tea. | a gram-negative, facultatively anaerobic strain was isolated from black tea. on the basis of 16s rrna gene sequence similarity comparisons, strain qc88-366t was grouped into the genus pantoea, being related most closely to the type strains of pantoea gaviniae (98.5 %) and pantoea calida (98.3 %); sequence similarities were ≤ 97.0 % to the type strains of other species of the genus pantoea. multilocus sequence analysis based on partial sequences of the gyrb, rpob, infb and atpd genes also reveale ... | 2015 | 26297578 |
| re: randomized clinical trial of brewed green and black tea in men with prostate cancer prior to prostatectomy. | 2015 | 26292860 | |
| the acute effects of green tea and carbohydrate coingestion on systemic inflammation and oxidative stress during sprint cycling. | green tea (camellia sinensis) has anti-oxidative and anti-inflammatory effects, which may be beneficial to athletes performing high-intensity exercise. this study investigated the effects of carbohydrate and green tea coingestion on sprint cycling performance and associated oxidative stress and immunoendocrine responses to exercise. in a crossover design, 9 well-trained male cyclists completed 3 sets of 8 repetitions of 100-m uphill sprint cycling while ingesting green tea and carbohydrate (tea) ... | 2015 | 26319564 |
| ca(2+) and cam are involved in al(3+) pretreatment-promoted fluoride accumulation in tea plants (camellia sinesis l.). | tea plant (camellia sinensis (l.) o. kuntze) is known to be a fluoride (f) and aluminum (al(3+)) hyper-accumulator. previous study showed that pre-treatment of al(3+) caused a significant increase of f accumulation in tea plants. however, less is known about the intricate network of al(3+) promoted f accumulation in tea plants. in this study, the involvement of endogenous ca(2+) and cam in al(3+) pretreatment-promoted f accumulation in tea plants was investigated. our results showed that al(3+) ... | 2015 | 26318146 |
| green tea component egcg, insulin and igf-1 promote nuclear efflux of atrophy-associated transcription factor foxo1 in skeletal muscle fibers. | prevention and slowing of skeletal muscle atrophy with nutritional approaches offers the potential to provide far-reaching improvements in the quality of life for our increasingly aging population. here we show that polyphenol flavonoid epigallocatechin 3-gallate (egcg), found in the popular beverage green tea (camellia sinensis), demonstrates similar effects to the endogenous hormones insulin-like growth factor 1 (igf-1) and insulin in the ability to suppress action of the atrophy-promoting tra ... | 2015 | 26344776 |
| micronutrients (b, co, cu, fe, mn, mo and zn) content in made tea (camellia sinensis l.) and tea infusion with health prospect: a critical review. | tea (camellia sinensis l.) is a perennial acidophilic crop, and known to be a non-alcoholic stimulating beverage that is most widely consumed after water. the aim of this review paper is to provide a detailed documentation of selected micronutrient contents, viz. boron (b), cobalt (co), copper (cu), iron (fe), manganese (mn), molybdenum (mo) and zinc (zn) in made tea and tea infusion. available data from the literature were used to calculate human health aspect associated with the consumption of ... | 2015 | 26478953 |
| transcriptome-based discovery of ap2/erf transcription factors related to temperature stress in tea plant (camellia sinensis). | tea plant (camellia sinensis) is an important natural resource for the global supply of non-alcoholic beverage production. the extension of tea plant cultivation is challenged by biotic and abiotic stresses. transcription factors (tfs) of the apetala 2 (ap2)/ethylene-responsive factor (erf) family are involved in growth and anti-stresses through multifaceted transcriptional regulation in plants. this study comprehensively analyzed ap2/erf family tfs from c. sinensis on the basis of the transcrip ... | 2015 | 26233577 |
| extraction kinetics of phytochemicals and antioxidant activity during black tea (camellia sinensis l.) brewing. | tea is the most consumed beverage in the world which is second only to water. tea contains a broad spectrum of active ingredients which are responsible for its health benefits. the composition of constituents extracted to the tea brew depends on the method of preparation for its consumption. the objective of this study was to investigate the extraction kinetics of phenolic compounds, gallic acid, caffeine and catechins and the variation of antioxidant activity with time after tea brew is made. | 2015 | 26226943 |
| global transcriptome and gene regulation network for secondary metabolite biosynthesis of tea plant (camellia sinensis). | major secondary metabolites, including flavonoids, caffeine, and theanine, are important components of tea products and are closely related to the taste, flavor, and health benefits of tea. secondary metabolite biosynthesis in camellia sinensis is differentially regulated in different tissues during growth and development. until now, little was known about the expression patterns of genes involved in secondary metabolic pathways or their regulatory mechanisms. this study aimed to generate expres ... | 2015 | 26220550 |
| does enzymatic hydrolysis of glycosidically bound volatile compounds really contribute to the formation of volatile compounds during the oolong tea manufacturing process? | it was generally thought that aroma of oolong tea resulted from hydrolysis of glycosidically bound volatiles (gbvs). in this study, most gbvs showed no reduction during the oolong tea manufacturing process. β-glycosidases either at protein or gene level were not activated during the manufacturing process. subcellular localization of β-primeverosidase provided evidence that β-primeverosidase was located in the leaf cell wall. the cell wall remained intact during the enzyme-active manufacturing pr ... | 2015 | 26212085 |
| identification and quantification of 1,3-dimethylbutylamine (dmba) from camellia sinensis tea leaves and dietary supplements. | 1,3-dimethylbutylamine (dmba), is a cns stimulant, which has recently been identified in multiple dietary supplements and sometimes labeled as a natural constituent of pouchung tea. dmba is an homologue of 1,3-dimethylamylamine (dmaa) which the us food and drug administration has attempted to remove from all dietary supplements after dmaa consumption was linked to strokes, heart disease, and sudden death. to address questions concerning the natural origin of dmba, three independent analytical me ... | 2015 | 26209774 |
| determinations for pesticides on black, green, oolong, and white teas by gas chromatography triple-quadrupole mass spectrometry. | black, green, white, and oolong teas, all derived from leaves of camellia sinensis, are widely consumed throughout the world and represent a significant part of the beverages consumed by americans. a gas chromatography-triple quadrupole-based method, previously validated for pesticides on dried botanical dietary supplements, including green tea, was used to measure pesticides fortified into black and green teas at 10, 25, 100, and 500 μg/kg. teas from 18 vendors of tea products were then surveye ... | 2015 | 26209005 |
| tea consumption and mortality of all cancers, cvd and all causes: a meta-analysis of eighteen prospective cohort studies. | epidemiological studies have demonstrated inconsistent associations between tea consumption and mortality of all cancers, cvd and all causes. to obtain quantitative overall estimates, we conducted a dose-response meta-analysis of prospective cohort studies. a literature search in pubmed and embase up to april 2015 was conducted for all relevant papers published. random-effects models were used to calculate pooled relative risks (rr) with 95 % ci. in eighteen prospective studies, there were 12 22 ... | 2015 | 26202661 |
| purple tea and its extract suppress diet-induced fat accumulation in mice and human subjects by inhibiting fat absorption and enhancing hepatic carnitine palmitoyltransferase expression. | a number of clinical trials have been completed using green tea and black tea to investigate their effect in controlling weight in overweight adults. the results of these investigations, however, have often been contradictory, with some trials reporting positive effects of tea supplementation and some trials reporting no effect. as a result, the use of these teas for weight loss is controversial. purple tea is a variety of green tea developed in kenya (called trfk306), which in addition to certa ... | 2015 | 26199579 |
| separation of polyphenols and caffeine from the acetone extract of fermented tea leaves (camellia sinensis) using high-performance countercurrent chromatography. | leaves from camellia sienensis are a popular natural source of various beverage worldwide, and contain caffeine and polyphenols derived from catechin analogues. in the current study, caffeine (caf, 1) and three tea polyphenols including (-)-epigallocatechin 3-o-gallate (egcg, 2), (-)-gallocatechin 3-o-gallate (gcg, 3), and (-)-epicatechin 3-o-gallate (ecg, 4) were isolated and purified by flow-rate gradient high-performance countercurrent chromatography (hpccc) using a two-phase solvent system c ... | 2015 | 26197310 |
| effects of cinnamon, cardamom, saffron, and ginger consumption on markers of glycemic control, lipid profile, oxidative stress, and inflammation in type 2 diabetes patients. | type 2 diabetes (t2d) may be caused by elevated oxidative stress, inflammation, and hyperglycemia. the phytochemicals in several herbal medicines are reported to effectively improve diabetes and to ameliorate diabetic complications. the aim of the present study was to determine the effects of cinnamon, cardamom, saffron, and ginger as supplementary remedies in t2d. | 2015 | 26177486 |
| neuroprotective properties of the standardized extract from camellia sinensis (green tea) and its main bioactive components, epicatechin and epigallocatechin gallate, in the 6-ohda model of parkinson's disease. | camellia sinensis (green tea) is largely consumed, mainly in asia. it possesses several biological effects such as antioxidant and anti-inflammatory properties. the objectives were to investigate the neuroprotective actions of the standardized extract (cs), epicatechin (ec) and epigallocatechin gallate (egcg), on a model of parkinson's disease. male wistar rats were divided into so (sham-operated controls), untreated 6-ohda-lesioned and 6-ohda-lesioned treated for 2 weeks with cs (25, 50, or 100 ... | 2015 | 26167188 |
| synergistic anticancer activity of biologicals from green and black tea on du 145 human prostate cancer cells. | there is considerable interest in the potential of botanicals in preventing and/or alleviating chronic ailments. among the most studied botanicals are compounds present in green and black teas. nontoxic tea polyphenols are potent antioxidants, and they also modulate several signalling pathways and inhibit proteins such as mmp-9 or protein plasminogen activator system, making them very attractive potential therapeutics. one criticism of the prophylactic or therapeutic use of green or black tea po ... | 2015 | 26155176 |
| green tea yogurt: major phenolic compounds and microbial growth. | the purpose of this study was to evaluate fermentation of milk in the presence of green tea (camellia sinensis) with respect to changes in antioxidant activity, phenolic compounds and the growth of lactic acid bacteria. pasteurized full fat cow's milk and starter culture were incubated at 41 °c in the presence of two different types of green tea extracts. the yogurts formed were refrigerated (4 °c) for further analysis. the total phenolic content was highest (p < 0.05) in air-dried green tea-yog ... | 2015 | 26139940 |
| evaluation of antioxidant interactions in combined extracts of green tea (camellia sinensis), rosemary (rosmarinus officinalis) and oak fruit (quercus branti). | green tea (camellia sinensis), rosemary (rosmarinus officinalis) and oak fruit (quercus branti) are of known medicinal plants used in traditional medicine. they provide substantial antioxidant activities but the possible antioxidant interaction between them has not been studied. in the present study first the bioactive compounds from these three plants were first extracted and thereafter assayed for total phenols, 2, 2-diphenyl-1- picrylhydrazyl (dpph) radical scavenging activity, total antioxid ... | 2015 | 26139926 |
| myocardial potency of bio-tea against isoproterenol induced myocardial damage in rats. | kombucha (bio-tea) is a beverage produced by the fermentation of sugared black tea using a symbiotic association of bacteria and yeasts. traditional claims about kombucha report beneficial effects such as antibiotic properties, gastric regulation, relief from joint rheumatism and positive influence on the cholesterol level, arteriosclerosis, diabetes, and aging problems. the present investigation was carried out to understand the preventive effect of kombucha on heart weight, blood glucose, tota ... | 2015 | 26139916 |
| high-throughput screening of vitamins and natural antioxidants in nutraceuticals from green tea extracts by liquid chromatography coupled to quadrupole orbitrap mass spectrometry. | a new analytical method was developed and validated for simultaneous analysis of 52 vitamins and natural antioxidants in nutraceutical products obtained from green tea (camellia sinensis) extracts. the automated extraction procedure was achieved in a simple disposable pipet extraction. ultra-high performance liquid chromatography and electrospray ionization quadrupole-orbitrap high-resolution mass spectrometry (uhplc q-orbitrap) was used for the separation and detection of all the analytes. the ... | 2015 | 26138600 |
| determination of polycyclic aromatic hydrocarbons in dry tea. | twenty-eight different tea samples sold in the united states were evaluated using high-performance liquid chromatography (hplc) with fluorescence detection (fld) for their contamination with polycyclic aromatic hydrocarbons (pahs). many pahs exhibit carcinogenic, mutagenic, and teratogenic properties and have been related to several kinds of cancer in man and experimental animals. the presence of pahs in environmental samples such as water, sediments, and particulate air has been extensively stu ... | 2015 | 26065515 |
| occurrence, biosynthesis and metabolism of theanine (γ-glutamyl-l-ethylamide) in plants: a comprehensive review. | theanine (γ-glutamyl-l-ethylamide) is the most abundant non-protein amino acid in tea leaves. in addition to camellia sinensis, theanine occurs in several plants belonging to the ericales. biosynthesis of theanine from glutamic acid and ethylamine by theanine synthetase is present in all organs of tea seedlings, but roots are the major site of theanine biosynthesis in adult tea trees. theanine is transported from roots to young leaves via the xylem sap. theanine is hydrolysed to glutamic acid an ... | 2015 | 26058162 |
| occurrence and de novo biosynthesis of caffeine and theanine in seedlings of tea (camellia sinensis). | caffeine (1,3,7-trimethyl xanthine) and theanine (γ-glutamyl-l-ethylamide) are the major nitrogen-containing secondary metabolites in tea leaves. the aim of the present study was to elucidate the relative concentration and amounts of these compounds and the de novo biosynthetic activity in different parts of tea seedlings grown for 27-, 106- and 205 days. the results indicated that caffeine and its biosynthetic activity occur only in leaves and stems, while theanine is distributed in all organs, ... | 2015 | 26058139 |
| chemopreventive opportunities to control basal cell carcinoma: current perspectives. | basal cell carcinoma (bcc) is a major health problem with approximately 2.8 million new cases diagnosed each year in the united states. bcc incidences have continued to rise due to lack of effective chemopreventive options. one of the key molecular characteristics of bcc is the sustained activation of hedgehog signaling through inactivating mutations in the tumor suppressor gene patch (ptch) or activating mutations in smoothened. in the past, several studies have addressed targeting the activate ... | 2015 | 26053157 |
| effects of temperature change and beverage on mechanical and tribological properties of dental restorative composites. | the aim of this study was to investigate the effects of temperature change and immersion in two common beverages on the mechanical and tribological properties for three different types of dental restorative materials. thermocycling procedure was performed for simulating temperature changes in oral conditions. black tea and soft drink were considered for beverages. universal composite, universal nanohybrid composite and universal nanofilled composite, were used as dental materials. the nanoindent ... | 2015 | 26046269 |
| black tea extract improves anti-oxidant profile in experimental diabetic rats. | the purpose of this study was to investigate the in vivo anti-oxidant effect of black tea extract (bte) supplemented to normal and alloxan-induced diabetic rats. | 2015 | 26120044 |
| quantification of total polyphenols, catechin, caffeine, l-theanine, determination of antioxidant activity and effect on antileishmanial drugs of ethiopian tea leaves extracts. | in this study four tea samples gumero black, wushwush black and wushwush green from agri- ceft plc and east africa black tea leaves from east african agribusiness plc were investigated for total polyphenols, caffeine, catechin and l-theanine content. | 2015 | 26109792 |
| a comparative proteomic analysis of the buds and the young expanding leaves of the tea plant (camellia sinensis l.). | tea (camellia sinensis l.) is a perennial woody plant that is widely cultivated to produce a popular non-alcoholic beverage; this beverage has received much attention due to its pleasant flavor and bioactive ingredients, particularly several important secondary metabolites. due to the significant changes in the metabolite contents of the buds and the young expanding leaves of tea plants, high-performance liquid chromatography (hplc) analysis and isobaric tags for relative and absolute quantitati ... | 2015 | 26096006 |
| tea polyphenols in parkinson's disease. | parkinson's disease (pd) is a common motor neurodegenerative disorder with multifactorial etiology that is an increasing burden on our aging society. pd is characterized by nigrostriatal degeneration which might involve oxidative stress, α-synuclein (αs) aggregation, dysregulation of redox metal homeostasis and neurotoxicity. although the exact cause remains unknown, both genetic and environmental factors have been implicated. among the various environmental factors tea consumption has attracted ... | 2015 | 26092629 |
| association between dietary pattern and risk of cardiovascular disease among adults in the middle east and north africa region: a systematic review. | this paper reviews the evidence related to the association of dietary pattern with coronary heart disease (chd), strokes, and the associated risk factors among adults in the middle east and north africa (mena) region. | 2015 | 26088003 |
| determination of aluminum and zinc in infusion tea cultivated in north of iran. | to determine aluminum and zinc levels in black tea cultivated in north of iran, 105 black tea samples were collected from the tea growing regions of guilan and mazandaran provinces and were analyzed for al and zn concentration of tea infusion. contents of all elements were analyzed three times separately by using an inductively coupled plasma atomic emission spectrometry (icp - aes). the solubility of al and zn in infusions at 5, 15 and 60 min with boiling water showed that the mean level of al ... | 2015 | 26085934 |
| influence of the interactions between tea (camellia sinensis) extracts and ascorbic acid on their antioxidant activity: analysis with interaction indexes and isobolograms. | products containing natural additives, including antioxidants, are usually perceived by consumers as safer than those with synthetic ones. natural antioxidants, besides having a preservative activity, may exert beneficial health effects. interactions between antioxidants may significantly change their antioxidant activity, thus in designing functional foods or food/cosmetic ingredients knowledge about the type of interactions could be useful. in the present study, the interactions between ascorb ... | 2015 | 26035225 |
| efficient extraction strategies of tea (camellia sinensis) biomolecules. | tea is a popular daily beverage worldwide. modulation and modifications of its basic components like catechins, alkaloids, proteins and carbohydrate during fermentation or extraction process changes organoleptic, gustatory and medicinal properties of tea. through these processes increase or decrease in yield of desired components are evident. considering the varied impacts of parameters in tea production, storage and processes that affect the yield, extraction of tea biomolecules at optimized co ... | 2015 | 26028699 |
| effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials. | tea has been proposed as an antihypertensive agent for individuals with elevated blood pressure, yet the evidence for this has not been systematically reviewed to date. | 2015 | 26024546 |
| impact of tea drinking upon tuberculosis: a neglected issue. | tuberculosis (tb) is a global public health issue posing serious harm to the human health. many studies have suggested that smoking and excessive alcohol consumption are risk factors for tb. laboratory evidence suggests that egcg in tea leaves can arrest the growth of tubercle bacillus. can drinking tea lead to decreased susceptibility of tb in humans? | 2015 | 26021567 |
| the impact of green tea consumption on the prevention of hemorrhagic stroke. | different types of tea may have varying effects on the risk of hemorrhagic stroke, but previous studies have generated inconsistent results. we performed a nationwide, multi-center, case-control study to evaluate the association between the consumption of tea and the risk of hemorrhagic stroke. | 2015 | 26021303 |
| work-related symptoms among workers exposed to black tea dust. | tea may be classified as unfermented green, semi-ferinented oolong and fermented black. all of these types are derived from camellia sinensis, the tea plant, which contains the low molecular weight (lmw) agent epigallocatechin gallate (egcg), probably responsible for allergic reactions. the aim of our study was to asses the work-related allergic symptoms and ige-mediated sensitivity among black tea packers. | 2015 | 26016041 |
| the combined use of camellia sinensis and metronomic zoledronate in 4t1 mouse carcinoma against tumor growth and metastasis. | in previous studies, we demonstrated that the green tea camellia sinensis (cs) water extract had potent antitumor and antimetastatic effects on 4t1 breast cancer. the metronomic regimen (0.0125 mg/kg twice a week for 4 weeks) of zoledronate (zol) was found to be effective in decreasing tumor burden and metastasis as compared with conventional regimen. the aim of the present study was to investigate the antitumor, antimetastatic and anti-osteolytic effects of the combined use of cs water extract ... | 2015 | 25998578 |
| tea consumption and endometrial cancer risk: meta-analysis of prospective cohort studies. | several lines of evidence suggest that tea consumption may reduce the risk of endometrial cancer due to antioxidant properties of tea, but the results of prospective data to date are inconsistent. we thus conducted a meta-analysis of prospective cohort studies to examine the relationship between tea consumption and endometrial cancer risk, using a random-effects model. we identified 5 eligible cohort studies, which included 231,870 female participants and 1831 cases for endometrial cancer. the p ... | 2015 | 25996185 |
| effect of black tea and black tea pomace polyphenols on α-glucosidase and α-amylase inhibition, relevant to type 2 diabetes prevention. | this study evaluates the potential mechanism of action and bioactivity of black tea and black tea pomace for type 2 diabetes prevention via inhibition of carbohydrate hydrolyzing enzymes. black tea leaves were extracted in hot water and black tea pomace was extracted in 70% acetone. the phenolic content of the water extract (wbt) and pomace acetone extracts (aobt) were 5.77 and 8.9 mg/ml, respectively, both based on the same concentration of solid tea in the extract. the water extract was subjec ... | 2015 | 25988132 |
| [responses of rhizosphere nitrogen and phosphorus transformations to different acid rain intensities in a hilly red soil tea plantation]. | tea (camellia sinensis) plantation in hilly red soil region has been long impacted by acid deposition, however its effects on nitrogen (n) and phosphorus (p) transformations in rhizosphere soils remain unclear. a 25-year old tea plantation in a typical hilly red soil region was selected for an in situ simulation experiment treated by ph 4.5, ph 3.5, ph 2.5 and control. rhizosihere and bulk soils were collected in the third year from the simulated acid deposition experiment. soil mineral n, avail ... | 2015 | 25985647 |
| polymorphism and evolution of ribosomal dna in tea (camellia sinensis, theaceae). | ribosomal dna (rdna) repeats often exhibit a high level of within-species homogeneity, but intra-individual polymorphism of rdna has been found in camellia species. in order to reveal the evolutionary pattern of rdna repeats in tea [camellia sinensis (l.) o. kuntze], we identified the 45s rdna loci, estimated their copy number, and cloned partial regions of them from different pcr products and from digested genomic dna. the results show that there are 3 loci (6 sites) containing 45s rdna in the ... | 2015 | 25871774 |
| heterozygosities and genetic relationship of tea cultivars revealed by simple sequence repeat markers and implications for breeding and genetic mapping programs. | genetic maps are essential tools for quantitative trait locus analysis and marker-assisted selection breeding. in order to select parents that are highly heterozygous for genetic mapping, the heterozygosity (hs) of 24 tea cultivars (camellia sinensis) was analyzed with 72 simple sequence repeat markers. in total, 359 alleles were obtained with an average of 4.99 per marker. the hs varied greatly from 37.5 to 71.0% with an average of 51.3%. on average, tea cultivars from fujian province showed a ... | 2015 | 25867299 |
| multiresidue pesticide analysis in nutraceuticals from green tea extracts by comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry. | a new analytical method was developed and validated for simultaneous analysis of 423 pesticides, isomers, and pesticide metabolites in nutraceutical products obtained from green tea (camellia sinensis) extract. response surface methodology was employed to optimize a generic extraction method. the automated extraction procedure was achieved in a simple disposable pipet extraction. comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry was used for the separation an ... | 2015 | 25865796 |
| determination of flavonol glycosides in green tea, oolong tea and black tea by uhplc compared to hplc. | an uhplc method for the determination of flavonol glycosides (fog) from green and oolong tea vs. black tea has been developed for the first time. sample clean-up method by means of polyamide column chromatography was optimized with multiple-step elution. using uhplc and hplc with gradient elution and photodiode array detection, eighteen fog compounds were determined with the aid of electrospray tandem mass spectrometry. these fog compounds were qualified on both uhplc and hplc, and this uhplc me ... | 2015 | 25863606 |
| protective effect of kombucha on rats fed a hypercholesterolemic diet is mediated by its antioxidant activity. | kombucha (kt) is claimed to have various beneficial effects on human health, but there is very little scientific evidence available in the literature. | 2015 | 25856715 |
| decaffeinated green tea and voluntary exercise induce gene changes related to beige adipocyte formation in high fat-fed obese mice. | we have previously reported that decaffeinated green tea extract (gte) in combination with voluntary exercise (ex) reduces metabolic syndrome in high fat-fed c57bl/6j mice. here, we examined for the first time the effect of treatment with 77 mg/g gte, ex, or both (gte + ex) on genes related to the conversion of white adipose tissue (wat) to brown fat-like adipose tissue (blat) in this model. gte+ex induced genes related to lipolysis (hormone sensitive lipase [3.0-fold] and patatin-like phospholi ... | 2015 | 25844091 |
| epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing mapk mediated inflammatory responses and oxidative stress. | green tea (camellia sinensis) is an extremely popular beverage worldwide. epigallocatechin-3-gallate (egcg) is one of the major catechins isolated from green tea and contributes to its beneficial therapeutic functions including antioxidant, anti-inflammatory and anti-cancer effects. however, the effect of egcg on mastitis is not yet known. this study was to investigate the protective potential of egcg against mastitis in rats. the rat mastitis model was induced by injecting lipopolysaccharide (l ... | 2015 | 25840281 |
| structure characterization of an arabinogalactan from green tea and its anti-diabetic effect. | a water-soluble polysaccharide, 7wa, with an average molecular mass of 7.1×10(4)da, was isolated from the leaves of green tea. monosaccharide composition analysis indicated that 7wa mainly contained arabinose and galactose in the molar ratio of 1.0:0.96. by using the methods of methylation analysis, partial hydrolysis, and nmr, 7wa was characterized to possess a backbone consisting of 1,3- and 1,6-linked galactopyranosyl residues, with branches attached to o-3 of 1,6-linked galactose residues, a ... | 2015 | 25839799 |
| anticancer effect of black tea extract in human cancer cell lines. | in this study we investigated effects of natural extract from the black tea camellia sinensis (bte) against human colon carcinoma cell line ht-29, human breast carcinoma cell line mcf-7, human alveolar carcinoma cell line a549 and healthy cell line nih-3t3. we identified concentration range for cytotoxic/antiproliferative effects using mtt assay and the trypan blue assay, gel electrophoresis we employed to determine the type of cell death induced by bte and dna damage we determined by comet assa ... | 2015 | 25825685 |
| assessing biochemical changes during standardization of fermentation time and temperature for manufacturing quality black tea. | in black tea manufacturing, one of the most important steps is fermentation which influences the quality of tea. the macerated tea leaves were fermented at various temperatures (20, 25, 30, 35 °c) for different duration. changes in polyphenoloxidase and peroxidase activities, depletion patterns of individual catechins, differences in individual theaflavin levels and formation of thearubigins were measured in leaves during fermentation. higher stability of polyphenoloxidase and peroxidase enzymes ... | 2015 | 25825546 |
| consumption of black and green teas as a dietary source of polyphenols in polish inhabitants of the mazovian region. | tea is a very popular drink throughout many parts of the world, that includes poland. the tea infusion (cup of tea) itself contains phenolic compounds with anti-oxidant properties that constitute 30% of the dry mass of tea leaves responsible for a health promoting effect on the human body. | 2015 | 25813071 |
| dietary and demographical risk factors for oesophageal squamous cell carcinoma in the eastern anatolian region of turkey where upper gastrointestinal cancers are endemic. | oesophageal squamous cell carcinoma (escc) is endemic in the eastern anatolian region of turkey. the present study was performed to identify risk factors for escc that specifically reflect the demography and nutritional habits of individuals living in this region. | 2015 | 25773844 |
| maternal total caffeine intake, mainly from japanese and chinese tea, during pregnancy was associated with risk of preterm birth: the osaka maternal and child health study. | the relation of maternal caffeine intake with birth outcomes is still inconclusive and has not been examined in japan, where the sources of caffeine intake are different from those in western countries. we hypothesized that maternal consumption of total caffeine and culture-specific major sources of caffeine would be associated with birth outcomes among japanese pregnant. the study subjects were 858 japanese women who delivered singleton infants. maternal diet during pregnancy was assessed using ... | 2015 | 25773355 |
| enhanced resistance to blister blight in transgenic tea (camellia sinensis [l.] o. kuntze) by overexpression of class i chitinase gene from potato (solanum tuberosum). | tea is the second most consumed beverage in the world. a crop loss of up to 43 % has been reported due to blister blight disease of tea caused by a fungus, exobasidium vexans. thus, it directly affects the tea industry qualitatively and quantitatively. solanum tuberosum class i chitinase gene (af153195) is a plant pathogenesis-related gene. it was introduced into tea genome via agrobacterium-mediated transformation with hygromycin phosphotransferase (hpt) gene conferring hygromycin resistance as ... | 2015 | 25772466 |
| model system-based mechanistic studies of black tea thearubigin formation. | thearubigins are the most abundant pigments found in black tea, comprising polyphenolic oxidation products, whose composition and chemical nature have remained unresolved until recently. in the course of studying the mechanism of thearubigin formation from green tea flavan-3-ols, a model system, based on electrochemical oxidation of one of the main tea flavan-3-ol substrates, epigallocatechin gallate (egcg), was employed. reaction intermediates and products were subsequently analysed using mass ... | 2015 | 25766828 |
| fermented green tea extract alleviates obesity and related complications and alters gut microbiota composition in diet-induced obese mice. | obesity is caused by an imbalance between caloric intake and energy expenditure and accumulation of excess lipids in adipose tissues. recent studies have demonstrated that green tea and its processed products (e.g., oolong and black tea) are introduced to exert beneficial effects on lipid metabolism. here, we propose that fermented green tea (fgt) extract, as a novel processed green tea, exhibits antiobesity effects. fgt reduced body weight gain and fat mass without modifying food intake. mrna e ... | 2015 | 25764354 |
| selected tea and tea pomace extracts inhibit intestinal α-glucosidase activity in vitro and postprandial hyperglycemia in vivo. | type 2 diabetes mellitus (t2dm) is a metabolic disorder characterized by postprandial hyperglycemia, which is an early defect of t2dm and thus a primary target for anti-diabetic drugs. a therapeutic approach is to inhibit intestinal α-glucosidase, the key enzyme for dietary carbohydrate digestion, resulting in delayed rate of glucose absorption. although tea extracts have been reported to have anti-diabetic effects, the potential bioactivity of tea pomace, the main bio waste of tea beverage proc ... | 2015 | 25906471 |
| integrated rna-seq and srna-seq analysis identifies chilling and freezing responsive key molecular players and pathways in tea plant (camellia sinensis). | tea [camellia sinensis (l) o. kuntze, theaceae] is one of the most popular non-alcoholic beverages worldwide. cold stress is one of the most severe abiotic stresses that limit tea plants' growth, survival and geographical distribution. however, the genetic regulatory network and signaling pathways involved in cold stress responses in tea plants remain unearthed. using rna-seq, dge and srna-seq technologies, we performed an integrative analysis of mirna and mrna expression profiling and their reg ... | 2015 | 25901577 |
| molecular cloning of a dehydration-responsive protein gene (mrd22) from mulberry, and determination of abiotic stress patterns of mrd22 gene expression. | a full-length cdna sequence coding for dehydration-responsive protein gene of mulberry tree, which we designated was mrd22 (genbank accession number: jq804833) was cloned based on mulberry expressed sequence tags (ests). mrd22 is 1503 bp long, contains a 334 bp 5'-utr (untranslated region) and a 563 bp 3'-utr, encodes 201 amino acids with a predicted molecular weight of 54.28 kda and an isoelectric point of 9.35. phylogenetic analysis based on mrd22 sequences from different species showed that m ... | 2015 | 25895340 |
| analysis of accumulation patterns and preliminary study on the condensation mechanism of proanthocyanidins in the tea plant [camellia sinensis]. | in the present study, proanthocyanidins were qualitatively and quantitatively identified using hydrolysis and thiolysis assays, np-hplc, hplc-esi-ms, maldi-tof-ms, (1)h-nmr, and (13)c-nmr techniques in different organs of tea plants. the results showed that in leaves, the tri-hydroxyl, cis- and galloylated flavan-3-ols were the main monomeric catechins units, and (epi)catechin was found to be the major unit of polymeric flavan-3-ols when the degree of polymerization was greater than five. in roo ... | 2015 | 25735226 |
| beverage habits and mortality in chinese adults. | there is limited research examining beverage habits, one of the most habitual dietary behaviors, with mortality risk. | 2015 | 25733477 |
| black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress. | hypertensive patients have been found to be associated with elevated levels of homocysteine, known as hyperhomocysteinemia. homocysteine (hcy) can induce endoplasmic reticulum (er) stress in endothelial cells. this study aims to investigate whether black tea (bt) protects against hypertension-associated endothelial dysfunction through alleviation of er stress. rat aortae and cultured rat aortic endothelial cells were treated with hcy, bt extract, and theaflavin-3,3'-digallate (tf3). male sprague ... | 2015 | 25976123 |
| hepatotoxicity of green tea: an update. | green tea (gt), obtained from the leaves of camellia sinensis (l.) kuntze (fam. theaceae), is largely used for its potential health benefits such as reduction in risk of cardiovascular diseases and weight loss. nevertheless, it is suspected to induce liver damage. present work reviews the hepatic adverse reactions associated with gt-based herbal supplements, published by the end of 2008 to march 2015. a systematic research was carried out on pubmed, medlineplus, scopus and google scholar databas ... | 2015 | 25975988 |
| anti-inflammatory activity of green versus black tea aqueous extract in a rat model of human rheumatoid arthritis. | recently, there has been an increasing interest in tea (camellia sinensis) as a protective agent against inflammatory diseases. here, we evaluated/compared the anti-inflammatory activity of two different doses (0.5 and 1.0 g/kg body weight) of green tea aqueous extract (gte, rich in catechins) and black tea aqueous extract (bte, rich in theaflavins and thearubigins) in rat adjuvant-induced arthritis (aia). | 2015 | 25964045 |
| protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats. | liver cirrhosis is responsible for hepatic fibrosis resulting in high mortality and is also a risk factor for developing hepatocellular carcinoma (hcc), which is the fifth most common cancer in men and the seventh in women globally. several studies have found effective anti-cancer activities of theaflavins, the major black tea polyphenols. the objective of this study was to investigate the protective effects of theaflavin-enriched black tea extracts (tf-bte) on hepatic fibrosis induced by dimeth ... | 2015 | 25927469 |
| evaluation of the anti-inflammatory and analgesic effects of green tea (camellia sinensis) in mice. | to evaluate the anti-inflammatory and analgesic effects of green tea (camellia sinensis) in mice. | 2015 | 25923256 |
| volatile glycosylation in tea plants: sequential glycosylations for the biosynthesis of aroma β-primeverosides are catalyzed by two camellia sinensis glycosyltransferases. | tea plants (camellia sinensis) store volatile organic compounds (vocs; monoterpene, aromatic, and aliphatic alcohols) in the leaves in the form of water-soluble diglycosides, primarily as β-primeverosides (6-o-β-d-xylopyranosyl-β-d-glucopyranosides). these vocs play a critical role in plant defenses and tea aroma quality, yet little is known about their biosynthesis and physiological roles in planta. here, we identified two udp-glycosyltransferases (ugts) from c. sinensis, ugt85k11 (csgt1) and u ... | 2015 | 25922059 |
| a case-control study of stomach cancer in relation to camellia sinensis in china. | the purpose of our study was to investigate the association between green tea (camellia sinensis) drinking habits and risk of stomach cancer in china. | 2015 | 25920351 |
| [biochemical processes at the stage of withering during black tea production]. | we determined the molecular weight and some properties of multiple forms of phenol oxidase from tea leaves and four other perennial plants. it was shown that multiple high- and low-molecular forms of phenol oxidase differed in substrate specificity. low-molecular forms of the enzyme mostly demonstrated hydroxylase activity, while high-molecular forms showed catechol oxidase activity. it was revealed that the withering stage of black tea production is accompanied by the formation of only high-mol ... | 2015 | 25707121 |
| polyphenolic rich traditional plants and teas improve lipid stability in food test systems. | the deleterious effects of lipid autoxidation are of major concern to the food industry and can be prevented by food antioxidants. in this vein, the phenolic contents and antioxidant potential of traditional plants of mauritius such as p. betle l. (piperaceae), m. koenigii l. sprengel. (rutaceae), o. gratissimum l. (lamiaceae), o. tenuiflorum l. (lamiaceae), and commercially available mauritian green and black teas were evaluated. their ferric reducing antioxidant power (frap) were compared to t ... | 2015 | 25694685 |
| daily consumption of white tea (camellia sinensis (l.)) improves the cerebral cortex metabolic and oxidative profile in prediabetic wistar rats. | diabetes mellitus (dm) is a major public health problem and its incidence is rising dramatically. the brain, particularly the cerebral cortex, is very susceptible to glucose fluctuations and hyperglycaemia-induced oxidative stress. tea (camellia sinensis (l.)) is widely consumed; however, the antidiabetic properties of white tea remain largely unexplored. in the present study, we investigated the effects of daily consumption of white tea on the cerebral cortex of prediabetic rats. the cerebral c ... | 2015 | 25716141 |
| tea and flavonoid intake predict osteoporotic fracture risk in elderly australian women: a prospective study. | observational studies have linked tea drinking, a major source of dietary flavonoids, with higher bone density. however, there is a paucity of prospective studies examining the association of tea drinking and flavonoid intake with fracture risk. | 2015 | 26269364 |
| africa's oesophageal cancer corridor: do hot beverages contribute? | hot beverage consumption has been linked to oesophageal squamous cell cancer (ec), but its contribution to the poorly understood east african ec corridor is not known. | 2015 | 26245249 |
| application of quechers based method for the determination of pesticides in nutraceutical products (camellia sinensis) by liquid chromatography coupled to triple quadrupole tandem mass spectrometry. | a quechers (quick, easy, cheap, effective, rugged, and safe) based method has been evaluated and validated for the determination and quantification of approximately 100 lc-amenable pesticides in nutraceutical products obtained from green tea (camellia sinensis). extraction was performed with acidified acetonitrile (acetic acid 1% (v/v)), and additional clean-up steps were not necessary. pesticides determination was achieved using ultra high performance liquid chromatography coupled to triple qua ... | 2015 | 25660875 |
| black tea lowers blood pressure and wave reflections in fasted and postprandial conditions in hypertensive patients: a randomised study. | hypertension and arterial stiffening are independent predictors of cardiovascular mortality. flavonoids may exert some vascular protection. we investigated the effects of black tea on blood pressure (bp) and wave reflections before and after fat load in hypertensives. according to a randomized, double-blind, controlled, cross-over design, 19 patients were assigned to consume black tea (129 mg flavonoids) or placebo twice a day for eight days (13 day wash-out period). digital volume pulse and bp ... | 2015 | 25658240 |
| green tea polyphenol epigallocatechin-3-gallate attenuates tnf-α-induced intercellular adhesion molecule-1 expression and monocyte adhesion to retinal pigment epithelial cells. | epigallocatechin-3-gallate (egcg) is a major polyphenol component of green tea (camellia sinensis) and demonstrates anti-oxidant, anticancer and anti-inflammatory properties. egcg has been shown to protect retinal pigment epithelium (rpe) against oxidative stress-induced cell death. the pathogenesis of diseases in the retina is usually initiated by local inflammation at the rpe cell layer, and inflammation is mostly associated with leukocyte migration and the secretion of pro-inflammatory cytoki ... | 2015 | 25644976 |
| cloning of a caffeoyl-coenzyme a o-methyltransferase from camellia sinensis and analysis of its catalytic activity. | epigallocatechin-3-o-(3-o-methyl) gallate (egcg3"me) present in leaves of camellia sinensis has many beneficial biological activities for human health. however, egcg3"me occurs naturally in tea leaves in extremely limited quantities. finding an enzyme from c. sinensis to catalyze the synthesis of egcg3"me is an alternative method to make up for the scarcity of egcg3"me in natural situations. in the present study, a complementary dna (cdna) encoding region and genomic dna of the caffeoyl-coenzyme ... | 2015 | 25644465 |