Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| treatment of bacterial vaginosis: a comparison of oral metronidazole, metronidazole vaginal gel, and clindamycin vaginal cream. | treatment options for bacterial vaginosis are numerous. the purpose of this study was to compare the efficacy of oral metronidazole, metronidazole vaginal gel, and clindamycin vaginal cream for the treatment of bacterial vaginosis using traditional clinical and laboratory methods, as well as a new dna probe test. we also determined the percentage of patients receiving each treatment who developed posttreatment vaginal candidiasis, a potential complication of treating bacterial vaginosis. | 1995 | 7595261 |
| [gardnerella vaginalis infection in heterosexual couples. ultrastructural study of desquamation cells of the stratified epithelium]. | bacterial vaginosis is one of the most frequent infections during the woman's reproductive age. lactobacilli normal flora is substituted by relatively elevated gardnerella vaginalis (gv), anaerobic bacteroids, mobiluncus and mycoplasma. the purpose of this study is to perform a morphological analysis of possible mechanisms for adhesion and penetration of gv in the heterosexual couple, in squamous epithelium at vaginal wall, as well as in seminal fluid. ten couples with positive gv culture with t ... | 1995 | 7768469 |
| the genital flora of women with intraamniotic infection. vaginal infection and prematurity study group. | the relationship of genital flora assessed at the end of the second trimester of pregnancy and intraamniotic infection diagnosed by clinical signs and symptoms during labor was evaluated. women were enrolled at 23-26 weeks of gestation and followed through delivery in the multi-center vaginal infections and prematurity study (1984-1989). among the cohort of 11,989 followed through delivery, 286 (2.4%) developed intraamniotic infection. the recovery of gardnerella vaginalis (relative risk [rr] = ... | 1995 | 7769281 |
| [bacterial vaginosis during chemotherapy for gynecological neoplasms. a therapeutic proposal]. | bacterial vaginosis (bv) is a well characterized disease, defined amsel's criteria, whose incidence is significantly increased during chemotherapy for gynecologic malignancies, as previously reported by the authors. nine patients out of 14 (64%) who were receiving adjuvant chemotherapy for gynecologic tumors showed a clinical and laboratory evidence of bacterial vaginosis and were treated with cetyltrimethilammonium naproxenate vaginal douches. results were analyzed up to the completion of oncol ... | 1995 | 7770150 |
| metronidazole during pregnancy. | 1995 | 7781879 | |
| [gardnerella vaginalis biotypes: modification of a proposed system]. | a modified scheme is proposed for biotyping gardnerella vaginalis based on detection of hippurate hydrolysis, beta-galactosidase (onpg) and lipase, and fermentation of arabinose, galactose and xylose. thirty three biotypes were found among 140 strains from women with and without bacterial vaginosis (non-specific vaginitis). the distribution of biotypes were found to be significantly different, being more predominant the biotypes 1a; 5g; 7a; 7d and 7g in women with vaginosis and the biotypes 5g a ... | 1995 | 7784728 |
| [the isolation of streptococcus morbillorum from vaginal exudates]. | we have tested 195 vaginal secretions sent by gynecology service of this hospital between the years 1988-1990. we achieved positive culture for streptococci in 58 (30%) of these cultures, 26 (44.8%) corresponding to streptococcus morbillorum 9 (15.5%), to gardnerella vaginalis 5 (8.6%), to enterococcus faecalis-durans and to streptococcus agalactiae, 3 (5.1%) to streptococcus mitis and milleri 2 (3.4%), to streptococcus bovis and cremoris, and 1 (1.7%) to streptococcus salivarius, equinus and sa ... | 1995 | 7716323 |
| [a new zoonosis--investigation of gardnerella vaginalis disease of fox. i. causative agent isolation and artificial infection]. | it is the first time that this paper reports on using improved rabbit blood agar culture medium to isolate 145 strains gardnerella vaginalis from the foxes and their abortion fortus organs of main fox farms. among the strains, 26 strains were isolated from the abortion foetus organs, isolation rate was 92.86%; 118 strains were isolated from the vaginal exeretion of the abortion and empty foxes, isolation rate was 34.01%; 1 strain was isolated from inguinal lymph node of the pelted positive fox, ... | 1995 | 7725679 |
| [a new zoonosis--investigation of gardnerella vaginalis disease of fox. ii. identification of pathogenic bacteria]. | 16 strains isolated from aborted foetus and vaginal exeretions of foxes were used for examination of cell morphology including fine structure of the cell wall and septa, test for homolysis, biochemical reactions and analysis of g+c content of the bacterial dna. the cells are pleomorphic bacilli and coccobacilli, gram stain reaction appear positive to variable, catalse and oxidase-negative, with a fermentative type of glucose metabolism, giving acetic and lactic acid as the major end products of ... | 1995 | 7725680 |
| genital ulcer disease in women infected with human immunodeficiency virus. | the purpose of this study was to determine the prevalence and microbiologic characteristics of genital ulcer disease in a population of human immunodeficiency virus-infected women. | 1995 | 7856685 |
| sterility of the uterine cavity. | in a prospective open study the sterility of the uterine cavity was evaluated in 99 women admitted for hysterectomy. the indications for hysterectomy were in most cases persistent irregular vaginal bleeding and fibromyomas of the uterus. samples for both aerobic and anaerobic bacteria, chlamydia trachomatis, yeasts and viruses were taken preoperatively from the apex of the vagina and cervical os. immediately after hysterectomy the uterus was opened under sterile conditions and samples obtained f ... | 1995 | 7900526 |
| in-vitro activity of purpuromycin and mdl 63,604 against microorganisms that cause vaginitis and vaginosis. | purpuromycin and its semi-synthetic derivative mdl 63,604 had in-vitro activity similar to that of amphotericin b against isolates of candida albicans. mdl 63,604 had activity similar to that of metronidazole against trichomonas vaginalis. both compounds were very active against most species of gram-positive and gram-negative anaerobes and against gardnerella vaginalis. mdl 63,604 had significantly lower mics than purpuromycin against t. vaginalis and most of the bacteria, probably due to antago ... | 1995 | 8821607 |
| in vitro ability of the group b streptococci to inhibit gram-positive and gram-variable constituents of the bacterial flora of the female genital tract. | the purpose of this study was to analyze the ability of septicemic and nonsepticemic isolates of group b streptococci (gbs) to inhibit in vitro the principal bacterial groups found in the normal bacterial flora of the female genital tract. | 1995 | 18476028 |
| vaginal candidiasis and other types of vaginitis. | the causes, diagnosis, treatment options, and recent research findings of vaginal infections in hiv-infected women are discussed. three common types of vaginitis are addressed: vaginal candidiasis, bacterial vaginosis, and trichomoniasis. the prevalence of candidiasis is an important indicator of hiv disease severity and data is provided that shows its frequency, compared to other genital infections, in hiv-positive women. | 1995 | 11362888 |
| virulence attributes of low-virulence organisms. | the vast majority of infections involving female pelvic structures arise from organisms that are members of the normal flora. in addition, exogenous organisms that invade through the lower genital tract must interact with organisms that are part of the host's flora. in contrast to the concept that the normal flora is entirely innocuous, recent research has begun to identify what appear to be virulence attributes among these ordinarily low-virulence organisms. most of our understanding of virulen ... | 1994 | 18475373 |
| microbiological patterns in vaginitis. | to determine the incidence and microbial aetiology of vaginitis, and the usefulness of gram staining of vaginal fluid in detecting the aetiology of vaginitis in sri lankan women. | 1994 | 7923459 |
| in vitro adhesiveness of gardnerella vaginalis strains in relation to the occurrence of clue cells in vaginal discharge. | g. vaginalis was isolated from 52.4 per cent patients with non-specific vaginitis. the haemagglutinating activity of g. vaginalis was strongest with human 'o' red cells and weaker reactions were observed with sheep and chick erythrocytes. haemagglutinating activity of g. vaginalis with human 'o' cells (1:16 titre) could be correlated with clue cells in vaginal discharge in 73 per cent patients while in lower titres, this correlation was not observed. | 1994 | 7927556 |
| [gardnerella vaginalis as urinary pathogen]. | to study the significance of gardnerella vaginalis in urine by comparing urine culture results, leucocytes count and clinical findings. | 1994 | 7948115 |
| expanded polytetrafluoroethylene patch versus braided polyester tape for the repair of incompetent cervix. | this study was done to evaluate pregnant patients with cervical incompetence using an expanded polytetrafluoroethylene (eptfe) patch versus the commonly used braided polyester tape, comparing the rate of local tissue reaction or onset of contractions, or both. | 1994 | 7952453 |
| study on treatment of bacterial vaginosis with oral administration of metronidazole or cefdinir. | bacterial vaginosis (bv) is considered to be one of the most common vaginal infections in women. fifteen symptomatic women with bv were enrolled in this study. ten patients with the diagnosis of bv were treated with 10 days oral administration of metronidazole (mtn), 500 mg twice a day, and five patients with cefdinir (cfdn), 300 mg three times a day. in the mtn therapy, the rate of abnormal vaginal discharge subjectively decreased from 100 to 60%, the rate of abnormal vaginal discharges objecti ... | 1994 | 7956461 |
| evaluation of api coryne system for identifying coryneform bacteria. | to identify rapidly and accurately coryneform bacteria, using a commercial strip system. | 1994 | 7962633 |
| a wet smear criterion for bacterial vaginosis. | to evaluate a simpler criterion for bacterial vaginosis than the recommended criterion of amsel. | 1994 | 7863139 |
| effects of cetyltrimethylammonium naproxenate on the adherence of gardnerella vaginalis, mobiluncus curtisii, and lactobacillus acidophilus to vaginal epithelial cells. | a decreased concentration or total disappearance of lactobacillus acidophilus in the vagina constitutes a frequent observation in bacterial vaginosis. | 1994 | 7871448 |
| [bacterial vaginosis. prevention of recurrence]. | bacterial vaginosis (bv) is the main cause of vaginitis. the condition is characterised by an abundant and odorous vaginal loss, but more than half the patients with demonstrable signs of bv do not report symptoms at all. gardnerella vaginalis (gv) is often associated with bv, but it is not the sole factor responsible, as is shown by the fact that it can be isolated in the vagina of women withbv. in 1992 and 1993, 2630 patients, 1460 of them gynaecological and 1170 obstetric, were admitted to th ... | 1994 | 7885610 |
| bacterial vaginosis: drugs versus alternative treatment. | bacterial vaginosis is one of the most common infectious disorders affecting women. it is caused by several microorganisms, including gardnerella vaginalis, bacteroides, beta-streptococci and mobiluncus/falcivibrio sp. bacterial vaginosis is thought to occur as a result of a change in vaginal ph mediated by the metabolic activity of anaerobic bacteria. this rise in vaginal ph interferes with the activity of vaginal lactobacilli which maintain vaginal acidity. several types of antibiotics have be ... | 1994 | 7885656 |
| studies on the anaerobic (bacterial) vaginosis among the bangladeshi women of reproductive age group. | vaginal swab from 190 patients aged between 15 to 45 years with the complaint of excessive and foul smelling vaginal discharge and 50 healthy controls of comparable age were studied. different diagnostic techniques used for the detection of g.vaginalis were compared. antibiogram of isolated g.vaginalis was also performed to determine the drug sensitivity pattern. g. vaginalis were isolated from 74 patients (38.9%) and from 6 controls (12%). the rate of isolation of g. vaginalis in the vaginal sw ... | 1994 | 7748151 |
| [genital microbial flora in a population of high obstetrical risk]. | there is increasing evidence showing the association between maternal genital infection, prematurity and neonatal or maternal morbidity. to know the genital flora of women attending a high risk pregnancy service, 73 consecutive pregnant women attending the high risk pregnancy service at the hospital san borja-arriarán from may to august 1992 were included in this study, 75.3% of the vaginal discharges corresponded to fluids of normal appearance and 24.7% were altered. the microorganisms most fre ... | 1994 | 7809430 |
| recurrent bacterial vaginosis unresponsive to metronidazole: successful treatment with oral clindamycin. | 1994 | 7810359 | |
| genital flora in pregnancy and its association with intrauterine growth retardation. | a study of risk factors for intrauterine growth retardation (iugr) was conducted among a cohort of 13,914 pregnant women enrolled in the multicenter vaginal infections and prematurity study. from 23 through 26 weeks of gestational age, cultures of specimens from the vagina and cervix were done for group b streptococci, neisseria gonorrhoeae, chlamydia trachomatis, trichomonas vaginalis, candida albicans, gardnerella vaginalis, mycoplasma hominis, ureaplasma urealyticum, and anaerobic gram-negati ... | 1994 | 7814541 |
| [value of the score for gram strains in the diagnosis of bacterial vaginosis]. | the interpretation of gram-stained slides of vaginal swab specimens is evaluated for the diagnosis of bacterial vaginosis and correlated with the isolation bacteria and clinical signs: thin homogeneous vaginal discharge, ph > or = 4.7, amine odor and presence of clue cells. gram stained smears were scored following a morphotype classification: (a)-lactobacillus morphotypes (scored 4 to 0), (b)-small gram negative (g. vaginalis, scored 0 to 4), (c)-curved gram variable rods (mobiluncus morphotype ... | 1994 | 7824329 |
| transhymenal cultures for sexually transmissible organisms. | vaginal swabs were examined for sexually transmissible organisms in 238 girls seen over a 36 month period from july 1989 to june 1992 inclusive. three groups were seen (age range 1.5-16.1 years), 165 in group 1 in whom there had been a disclosure of sexual abuse, 35 in group 2 where there was a strong suspicion of sexual abuse, and 38 with vulvovaginitis who formed group 3. the isolation of recognised sexually transmitted organisms was low; however, of group 1 19% were colonised with gardnerella ... | 1994 | 7826112 |
| a longitudinal study of bacterial vaginosis during pregnancy. | to determine the longitudinal changes in the incidence of vaginosis in pregnancy. | 1994 | 7826957 |
| sexually transmitted diseases. | 1994 | 7838609 | |
| prevalence of vaginitis, syphilis and hiv infection in women in the orange free state. | to determine the prevalence of vaginitis, syphilis and hiv infection in women in the orange free state. | 1994 | 7839281 |
| bacterial vaginosis in a district genitourinary medicine department: significance of vaginal microbiology and anaerobes. | the aim of this study was to correlate the significance of vaginal microbiology, in particular its anaerobic component, to the presence of bacterial vaginosis (bv), and to review the clinical criteria used in the diagnosis of this condition. ninety-two female patients who received routine std screening were studied. after routine history, presence and character of vaginal discharge and vaginal ph were noted, an amine test performed, and a wet stain observed microscopically. routine gram stain sm ... | 1994 | 7849117 |
| [perinatal infections. infection as etiological factor of preterm labor]. | on the ground of contemporary medical literature and our own observations, we have tried to estimate the participation of microorganism infection in preterm labor. in this article, we present mechanism, currently recognized as the most probable, that are leading to preterm labor under condition of perinatal infections. one of them seems to be the production of enzymes by pathological strains. those enzymes are considered to stimulate decidual and amniotic cells to arachidonic acid metabolism and ... | 1994 | 7597173 |
| determination of gardnerella vaginalis genome size by pulsed-field gel electrophoresis. | the chromosomal dna of four strains of gardnerella vaginalis were digested with rare cutting restriction enzymes and analyzed by pulsed-field gel electrophoresis (pfge). the four strains studied were two clinical isolates (gvp 004 & gvp 007) and two american type culture collection strains (atcc 14018 & atcc 14019). the restriction enzyme sfii generated two dna fragments of about 0.6 mb and 1.1 mb in all four strains giving a g. vaginalis genome size of about 1.7 mb. a similar genome size was ca ... | 1994 | 7584037 |
| pcr primers and probes for the 16s rrna gene of most species of pathogenic bacteria, including bacteria found in cerebrospinal fluid. | a set of broad-range pcr primers for the 16s rrna gene in bacteria were tested, along with three series of oligonucleotide probes to detect the pcr product. the first series of probes is broad in range and consists of a universal bacterial probe, a gram-positive probe, a bacteroides-flavobacterium probe, and two probes for other gram-negative species. the second series was designed to detect pcr products from seven major bacterial species or groups frequently causing meningitis: neisseria mening ... | 1994 | 7512093 |
| evaluation of the etest for antimicrobial spectrum and potency determinations of anaerobes associated with bacterial vaginosis and peritonitis. | one hundred ninety-seven anaerobic organisms (24 gardnerella vaginalis, 16 mobiluncus spp., 19 peptostreptococcus spp., 20 lactobacillus spp., 20 prevotella bivia/disiens, 81 bacteroides fragilis group, 12 clostridium spp., and five fusobacterium spp.) were processed by the etest (ab biodisk, solna, sweden) and a reference (brucella blood agar) method against 10 antimicrobial agents. for the bacterial vaginosis-associated pathogens, the etest was more reproducible and correlated acceptably with ... | 1994 | 7705035 |
| lea's shield, a new barrier contraceptive preliminary clinical evaluations three-day tolerance study. | in this study the lea's shield was evaluated for its tolerance by women who wore the device for three consecutive days. ten women who wore the lea's shield for 72 hours completed the tolerance study without adverse effects. examination of the cervix and vagina revealed that the device did not provoke any significant cellular or microbial changes among the wearers. no major changes in the appearance or prevalence of vaginal flora occurred in the women after three days of wearing the device. a gra ... | 1994 | 7705097 |
| changes in vaginal flora during pregnancy and association with preterm birth. | a prospective study of the vaginal flora changes between midtrimester and labor was undertaken in 560 women; 337 had intact membranes and were in labor when swabs were taken. of these, 45 delivered preterm. gardnerella vaginalis, ureaplasma urealyticum (both associated with preterm birth when present in midtrimester), and mycoplasma hominis commonly persisted between midtrimester and labor, particularly in the preterm cohort (24 [65%] of 37 midtrimester isolates), and these organisms were seldom ... | 1994 | 8077737 |
| variability of polymerase chain reaction-based detection of human papillomavirus dna is associated with the composition of vaginal microbial flora. | the results of repeated human papillomavirus (hpv) dna testing were compared to changes in cervical pathology and the composition of vaginal microorganisms. a cohort of 19 women with hpv cervical infections in the absence of cervical intraepithelial neoplasia at enrollment was reexamined on average at 7.3-month intervals over a 2-year period. at each follow-up visit, cytological and colposcopic examinations were done and vaginal microorganisms were assessed quantitatively by gram staining of sec ... | 1994 | 8083669 |
| [biocenosis of the vagina and infection with chlamydia trachomatis]. | the authors have examined 379 women for infection by chlamydia trachomatis, performing vaginal smears and routine bacterial cultures. c. trachomatis was discovered in 33.2% of the women, most frequently accompanied by erosion of the collum, cervicitis and cin-ca. women with c. trachomatis had the following levels of vaginal purity: 1-44.4%, 2-23.0%, 3 and 4-29.4%, 3.2% -leukocytes only. leukocytes were present in significantly more women with level 1 of vaginal purity than in the control group. ... | 1994 | 7967934 |
| patient education. diagnosis and treatment of bacterial vaginosis. | this paper continues our series looking at some of the information patients may require with regard to common health problems. providing information that is comprehensible is an important part of the nurse's role. it is vital that information, usually provided for particular specialties, is made available to all health-care workers and patients. | 1994 | 7971311 |
| [the use of eubiotics for the treatment of bacterial vaginosis]. | the study was concerned with the problem of the treatment of bacterial vaginosis. to correct the dysbiotic condition in the vagina, a two-stage procedure was applied. the first stage was aimed at the provision of the normal physiological condition of the vaginal medium and mucosa and the second stage was aimed at the provision of the normal microbiocenosis. at the second stage biological preparations such as lactobacterin, acylact, bifidumbacterin and bifidin were used. the recovery was stated i ... | 1994 | 7979792 |
| [vulvo-cervico-vaginal inflammatory pathologies in childhood and adolescence. our experience]. | one hundred and twenty-seven pediatric and adolescent patients suffering from vulvo-vaginitis underwent clinical and instrumental tests. the results of bacterioscopic and cultural test were negative in 39 (31.7%) patients due to the probable intervention of local hormonal, allergic and/or irritative factors. the tests used by the authors revealed phlogosis in 88 patients (68.3%) which was aspecific in 58 cases (65.9%) and specific in 30 (34.1%). while aspecific phlogosis were basically caused by ... | 1994 | 7984324 |
| sexually transmitted diseases in children: non viral including bacterial vaginosis, gardnerella vaginalis, mycoplasmas, trichomonas vaginalis, candida albicans, scabies and pubic lice. | 1994 | 8039788 | |
| [urethro-adnexitis in the man and acute urethral syndrome in the woman. microbiological and immunologic studies of etiologic classification]. | both common pathogens and unconventional, fastidious bacteria, viruses, parasites, and fungi are causative agents in male urethro-adnexitis and in female acute urethral syndrome. uropathogens, neisseria gonorrhoeae, treponema pallidum, mycobacterium tuberculosis, chlamydia trachomatis, mycoplasma spp., haemophilus ducreyi, calymmatobacterium granulomatis, gardnerella vaginalis, anaerobic bacteria, herpes simplex virus type ii (hsv ii), papillomaviruses (hpv), trichomonas vaginalis and candida sp ... | 1994 | 8053087 |
| bacteremia due to gardnerella vaginalis: report of two cases. | 1994 | 8054429 | |
| cytopathologic changes associated with intrauterine contraceptive devices. a review of cervico-vaginal smears in 350 women. | cervico-vaginal smears from 350 iucd users were analysed to ascertain the range of abnormalities induced in the genital tract of these women. alteration of the microbial environment, inflammatory, degenerative, reparative and proplastic epithelial changes were the salient cytological findings. the clinical implications of these are briefly discussed. | 1994 | 8057995 |
| bacterial vaginosis in pregnancy and efficacy of short-course oral metronidazole treatment: a randomized controlled trial. | to characterize the natural history of bacterial vaginosis in pregnancy and to assess the efficacy of short courses of oral metronidazole therapy for long-term suppression of bacterial vaginosis flora. | 1994 | 8058228 |
| carriage of gardnerella vaginalis in the urethra of indian men. | a total of 310 consecutive sexually active men attending sexually transmitted disease clinic of the nehru hospital, chandigarh, were studied to assess the prevalence of g vaginalis. non-gonococcal urethritis (ngu) was diagnosed in 53, acute gonococcal urethritis (agu) in 20, psychosomatic disorders in 50 and genital ulcer disease in 187 patients. g. vaginalis was isolated in 11 patients (3.5%) only. of these 11 isolates, 4(7.5%) were from patients with ngu, 2(10.0%) from men diagnosed to have ag ... | 1994 | 8088884 |
| [gardnerella vaginalis: transport, microscopy, testing resistance]. | g. vaginalis is an important pathogen in the aetiology of bacterial vaginosis. therefore, we investigated the influence of transport systems in isolation, a scoring system for gram stains, and susceptibility to antimicrobial agents. the comparison between a simple (transwab) and a sophisticated (port-a-cul) system showed no differences with regard to for instance enterococcus faecalis or escherichia coli; however, isolation of g. vaginalis, a fastidious microorganism, was significantly higher (a ... | 1994 | 8719002 |
| evaluation of affirm vp microbial identification test for gardnerella vaginalis and trichomonas vaginalis. | a commercial system (affirm vp microbial identification test; microprobe corp.) for detection of vaginal pathogens was evaluated with 176 consecutive women attending a sexually transmitted disease clinic for genital complaints. vaginal swab specimens were used for culture of gardnerella vaginalis and trichomonas vaginalis, preparation of a vaginal smear for gram stain interpretation, and wet mount evaluation. an additional swab was used to evaluate the 30-min nonisotopic oligonucleotide probe te ... | 1994 | 8126171 |
| bacterial vaginosis and vaginal microorganisms in idiopathic premature labor and association with pregnancy outcome. | the vaginal microflora of 49 women in idiopathic preterm labor was compared with that of 38 term controls to determine whether the presence of bacterial vaginosis (bv) and/or specific microorganisms would influence the rate of preterm delivery. demographic factors, pregnancy outcome, and reproductive history were also studied. bv, as defined by the presence of clue cells in a vaginal wet mount and characteristic microbial findings in a stained vaginal smear and vaginal culture, was more common i ... | 1994 | 8126176 |
| bacterial vaginosis is associated with prematurity and vaginal fluid mucinase and sialidase: results of a controlled trial of topical clindamycin cream. | the pathogenesis of preterm birth and other adverse pregnancy outcomes linked with reproductive tract infection remains poorly understood. mucolytic enzymes, including mucinases and sialidases (neuraminidase), are recognized virulence factors among enteropathogens and bacteria that cause periodontal infection. perturbation of maternal cervicovaginal mucosa membrane host defenses by such enzyme-producing microorganisms may increase the risk of subclinical intrauterine infection during pregnancy a ... | 1994 | 8166188 |
| in vitro antibacterial activity of fk037, a new parenteral broad-spectrum cephalosporin, against recent clinical isolates in the fields of obstetrics and gynecology. | the antibacterial activity of a new parenteral cephalosporin, fk037 was assessed against recent aerobic and anaerobic strains isolated from patients in the fields of obstetrics and gynecology during the period between january 1992 and june 1993. the mics of fk037 for 90% of the clinical isolates tested were 0.10 microgram/ml for escherichia coli and klebsiella pneumoniae, 0.20 microgram/ml for streptococcus agalactiae, 0.39 microgram/ml for gardnerella vaginalis, 0.78 microgram/ml for staphyloco ... | 1994 | 8205934 |
| ionic factors regulating the interaction of gardnerella vaginalis hemolysin with red blood cells. | we have studied the hemolytic properties of an exotoxin released by gardnerella vaginalis (gvh). we found that hemolysis induced by gvh is modulated by the composition of the isotonic buffer in which the red cells are suspended. in particular, low ph enhances its lytic activity, whereas low ionic strength and divalent cations diminish it. the inhibitory effects of reduced salt concentration and divalent cations occur despite normal binding of the toxin to the cells. this suggests that some post- ... | 1993 | 8241250 |
| internal bacterial flora of solid uterine cervical cancer. | twenty-five patients with uterine cervical cancer (two cases stage o; four cases stage ia; five cases stage ib; one case stage iia; ten cases stage iib; two cases stage iiia; one case stage iva) served as the subjects. the bacterial flora inside the cervical cancers was investigated using the optimal technique. there was mixed abnormal aerobic and anaerobic bacterial flora in all subjects. the average number of bacterial species isolated from inside the cervical cancers was 6.3. the predominant ... | 1993 | 8270797 |
| treatment of post-cesarean section endometritis with ampicillin and sulbactam or clindamycin and gentamicin. | seventy-seven patients were prospectively enrolled in a randomized clinical trial to compare two antimicrobial regimens for the treatment of post-cesarean section endometritis. the two groups were not significantly different with respect to age, race, gravidity, parity, hours in labor, cesarean section indication, preoperative or postoperative hemoglobin/hematocrit, pretreatment white blood cell count or pretreatment temperature. pretreatment urine, blood and endometrial cultures were obtained. ... | 1993 | 8277478 |
| [vaginitis and vaginosis. comparison of two periods]. | vaginitis is the most frequent gynecological disease. it is characterized by objective and subjective signs of inflammation and differs from bacterial vaginosis (bv) which is an abnormal condition of the vaginal ecosystem caused by the excessive growth of aerobic and anaerobic flora normally present in the vagina with an increased risk of pelvic inflammatory disease (pid). the authors report the results of a study carried out at the centre for gynecological infections at the clinic of obstetrics ... | 1993 | 8278079 |
| [anaerobic bacteria and gynecologic infections]. | the normal vaginal flora consists of a wide variety of bacteria and the composition of this microflora is influenced by hormonal, metabolic and pharmacological factors. an increased concentration of a mixed anaerobic flora (mobiluncus, prevotellae, peptostreptococci and gardnerella vaginalis) appears to be an early stage in the development of bacterial vaginosis or in the infection of the upper genital tract. women with bacterial vaginosis are at increased risk of bartholinitis, skenitis, pelvic ... | 1993 | 8290794 |
| [prevalence of 4 agents of sexually transmitted diseases in leukorrhea in abidjan (ivory coast)]. | 6,603 women with vaginal discharges were investigated for genital infection with four sexually transmitted diseases. germs of vaginitis were isolated with prevalence as following: c. albicans 25%, g. vaginalis 17.4%, t. vaginalis 8.2%. cervicitis with n. gonorrhoeae represented 3.2% of cases. | 1993 | 8292912 |
| [gardnerella vaginalis in infections of reproductive organs]. | the study was aimed at multidirectional studies on bacteria isolated from smears from vagina and cervix uteri in 226 patients with inflammatory states of their reproductive organs. most frequently isolated aerobic bacteria were gram-negative--27%, mainly e. coli, and enterococcus faecalis--in 18% of cases. anaerobic bacteria were isolated in 81% of cases: gardnerella vaginalis was isolated in 28% and lactobacillus in 53% of cases. other anaerobic bacteria were: peptococcus asaccharolyticus (15.5 ... | 1993 | 8309297 |
| the normal vaginal flora, h2o2-producing lactobacilli, and bacterial vaginosis in pregnant women. | in this study of the vaginal flora of 171 pregnant women in labor at term, the flora was categorized as normal (lactobacillus predominant), intermediate, or representative of bacterial vaginosis (bv) on the basis of a vaginal smear. bv was diagnosed in 39 women (23%); the vaginal flora was classified as normal in 50% of cases and as intermediate in 27%. h2o2-producing lactobacilli were recovered from 5% of women with bv, 37% of those with an intermediate flora, and 61% of those with a normal flo ... | 1993 | 8324131 |
| the vagina as an ecologic system. current understanding and clinical applications. | recent advances in understanding the mechanisms of dominance of the healthful microecology by lactobacillus acidophilus through microbicidal enzyme systems has led to renewed interest in ecologic approaches to vaginal health maintenance and treatment of vaginosis and vaginitis. review of pertinent research suggests that due to inadequate adherence of lactobacilli from dairy sources, contaminants in commercial sources, and lack of evidence of effectiveness in sparse clinical trials, intravaginal ... | 1993 | 8331425 |
| the microbiology of bacterial vaginosis. | a group of microorganisms are present concurrently in high concentrations in the vaginas of women with bacterial vaginosis. the major members of the group are gardnerella vaginalis, anaerobic gram-negative rods belonging to the genera prevotella, porphyromonas and bacteroides, peptostreptococcus species, mycoplasma hominis, ureaplasma urealyticum, and often mobiluncus species. facultative species of lactobacillus are present in lower concentrations and are less prevalent in bacterial vaginosis t ... | 1993 | 8357043 |
| diagnostic microbiology of bacterial vaginosis. | bacterial vaginosis is characterized microbiologically by replacement of the lactobacillus-predominant vaginal flora by gardnerella vaginalis, bacteroides species, mobiluncus species, and genital mycoplasmas. a standardized, laboratory-based diagnostic test for bacterial vaginosis is desirable in those instances in which a microscope is unavailable in the clinic or when the evaluator of the wet mount examination is inexperienced at recognizing clue cells. vaginal cultures have excellent sensitiv ... | 1993 | 8357044 |
| chorioamnionitis and bacterial vaginosis. | an improved understanding of bacterial vaginosis and of clinical intraamniotic infection and histologic chorioamnionitis has produced data showing strong associations among these conditions. it has recently been shown that the microorganisms in both bacterial vaginosis and clinical intraamniotic infection are similar, of which anaerobes, gardnerella vaginalis, and mycoplasma hominis are the predominant organisms in both. furthermore, in the amniotic fluid of women with intraamniotic infection, s ... | 1993 | 8357045 |
| historical review of the treatment of bacterial vaginosis. | the review of the treatment of bacterial vaginosis parallels the history of this syndrome. before the syndrome was defined, treatment was local and nonspecific. gardner and dukes defined nonspecific vaginitis in 1955 as an infection caused by haemophilus vaginalis. therapy was directed toward this aerobic "pathogen" and included oral tetracycline and a triple sulfa vaginal cream. subsequent studies indicated success with this regimen as well as with ampicillin, a drug with good aerobic activity. ... | 1993 | 8357049 |
| in vitro antimicrobial activity of tioconazole and its concentrations in vaginal fluids following topical (vagistat-1 6.5%) application. | in vitro assays demonstrated that clinical yeasts were significantly more inhibited by tioconazole (mic50, < or = 0.5 microgram/ml) than by fluconazole (mic50, 8 micrograms/ml). tioconazole also exhibited high potency against most molds (alterneria spp. and acremonium spp.). all candida tropicalis isolates had mics of 8 micrograms/ml, four-fold greater than any other candida spp. generally gram-negative bacteria were less susceptible to tioconazole. moraxella catarrhalis (mic90, 2 micrograms/ml) ... | 1993 | 8359005 |
| [isolation of gardnerella vaginalis from vaginal discharge specimens]. | in this study specimens taken from 93 patients who admitted to outpatient clinics of ssk ankara gynaecology and obstetrics hospital with vaginal discharge were examined for g. vaginalis, t. vaginalis, c. albicans and n. gonorrhoeae. we evaluated the smell, ph, direct microscopic examinations, stained preparations and specific culture results of the discharges which were taken from posterior fornix. we isolated g. vaginalis from 13 patients (13.9%), t. vaginalis from 5 patients (5.3%) and c. albi ... | 1993 | 8361406 |
| [quantitative study of vaginal flora during the menstrual cycle]. | the aerobic and facultatively anaerobic vaginal flora of 242 healthy women were examined during menstrual cycles. the most frequently isolated microorganisms at the first premenstrual examination were coagulase-negative staphylococci (61%), followed by enterococci (25%), gardnerella vaginalis (19%), diphtheroids (12%), group b streptococci (6.8%), escherichia coli (5.4%) and candida spp. (4%). the isolation rate of all species, except candida and gardnerella vaginalis increased during menstruati ... | 1993 | 8375634 |
| antimicrobial activity and spectrum of rifaximin, a new topical rifamycin derivative. | rifaximin, a rifamycin derivative, was evaluated in vitro to assess its spectrum and potency against a wide variety of bacteria, yeasts, viruses, and parasites. high concentrations of rifaximin were often used to reflect topically achieved levels since this compound is poorly absorbed by oral route. like rifampin, rifaximin possessed best activity against staphylococcus spp. (mic50 < or = 0.015 microgram/ml), streptococcus spp. (mic50s, < or = 0.03-0.12 microgram/ml), enterococcus spp. (mic50s, ... | 1993 | 8385592 |
| phosphorylation and activation of the arachidonate-mobilizing phospholipase a2 in macrophages in response to bacteria. | the role of potential target enzymes in the protein-kinase-c-independent eicosanoid response triggered by certain bacteria in murine peritoneal macrophages [svensson, u., holst, e. & sundler, r. (1991) eur. j. biochem. 202, 699-705] has been investigated. the eicosanoid response was found to be due to an increase in the mobilization of arachidonate rather than to inhibition of arachidonate esterification or activation of the cyclooxygenase pathway and to be accompanied by a persistent increase i ... | 1993 | 8386632 |
| erythromycin versus metronidazole in the treatment of bacterial vaginosis. | of 101 women, 15-50 years of age, presenting with vaginal discharge, 34 had bacterial vaginosis and were randomly assigned to a seven-day course of oral treatment with either erythromycin (0.5 g b.i.d.) or metronidazole (0.4 g b.i.d.) in a single-blind, cross-over study. treatment failure (> or = three clinical signs of bacterial vaginosis) occurred in 13 (81%) of 16 patients given erythromycin, as compared with three (17%) of 18 women treated with metronidazole (p < 0.001). persistence of gardn ... | 1993 | 8394627 |
| perinatal effects of gardnerella vaginalis deciduitis in the rabbit. | we determined the effects of intrauterine infection with gardnerella vaginalis on maternal and fetal outcome in the rabbit. | 1993 | 8456914 |
| tumour necrosis factor alpha and interleukin 2 in normal and infected human seminal fluid. | the presence of cytokines such as the tumour necrosis factor alpha (tnf alpha) and interleukin 2 (il2) in human spermatozoa is still to be defined. the aim of this study was to measure the concentration of both soluble factors in seminal fluid. data from normal semen samples (n = 24) confirmed the presence of il2 (258 +/- 84 fmol/ml corresponding to 953 +/- 369 fmol/total volume of ejaculate) and tnf alpha (62.2 +/- 16.4 fmol/ml corresponding to 231.3 +/- 86 fmol/total volume of ejaculate). a si ... | 1993 | 8473457 |
| [how can reinfection by gardnerella vaginalis be prevented?]. | 1993 | 8479572 | |
| [the definition and epidemiology of bacterial vaginosis]. | bacterial vaginosis is a condition with a flora change in the vaginal where a lactobacilli-dominated flora is exchanged with an abundant complex flora dominated by strict and facultative anaerobic bacteria. the condition seldom occurs in prepubertal girls and post-menopausal women, suggesting an hormonal component in its etiology. recurrent episodes of bacterial vaginosis are frequent. three out of four criteria should be fulfilled for establishing the diagnosis of bacterial vaginosis, i.e., an ... | 1993 | 8484086 |
| [clinical and colposcopic aspects of bacterial vaginosis]. | bacterial vaginosis is characterized by an uniform, malodorous, white-grey discharge. the presenting symptom is generally the unpleasant smell of the vaginal discharge, particularly following the menses or intercourse. other functional signs, such as pruritus, dysuria and dyspareunia are rare. inflammatory signs are frequent, and can be revealed by colposcopy with the lugol test: this shows punctuate colpitis with small regular points corresponding histologically to an inflammatory focus in the ... | 1993 | 8484087 |
| [the bacteriologic diagnosis of bacterial vaginosis in an urban practice]. | the term "bacterial vaginosis" carries both bacteriologic and clinical connotations. indeed, it implies that the vagina is uninflamed (as shown by the absence of polymorphonuclear neutrophils), but that potential pathogens (particularly gardnerella vaginalis) are present. many studies conducted over the last 10 years have shown that a tentative diagnosis is simple to make, based on the sniff test, the aspect of the vaginal discharge, the presence of clue cells, and the absence of polymorphonucle ... | 1993 | 8484088 |
| [recent bacteriologic data: from physiopathology to treatment]. | bacterial vaginosis is characterized by a change in the vaginal ecosystem in which lactobacillus spp, the dominant members of the normal flora, are replaced by an association of various bacterial species including gardnerella vaginalis, anaerobes (bacteroides spp, prevotella spp, porphyromonas spp, peptostreptococcus spp and mobiluncus spp) and mycoplasma hominis. the reasons for this imbalance are unknown, although the loss of lactobacilli that produce hydrogen peroxide (which is toxic for g. v ... | 1993 | 8484089 |
| comparative susceptibility of the bacteroides fragilis group species and other anaerobic bacteria to meropenem, imipenem, piperacillin, cefoxitin, ampicillin/sulbactam, clindamycin and metronidazole. | the in-vitro activity of meropenem, imipenem, piperacillin, cefoxitin, ampicillin/sulbactam, clindamycin and metronidazole was determined against 395 strains of strict and facultative anaerobes, including gardnerella vaginalis, lactobacillus spp. and mobiluncus spp. the activities of meropenem and imipenem were within one dilution of their mic50 and mic90 values. one isolate of bacteroides fragilis, two of bacteroides distasonis, and two of bacteroides ovatus showed resistance or diminished susc ... | 1993 | 8486570 |
| efficacy of intravaginal 0.75% metronidazole gel for the treatment of bacterial vaginosis. | to assess the efficacy of 0.75% metronidazole vaginal gel, formulated at ph 4.0, for the treatment of bacterial vaginosis in a double-blind, placebo-controlled crossover trial. | 1993 | 8497364 |
| prevalence of cervical pathogens in women with and without inflammatory changes on smear testing. | to assess correlation between nonspecific cervicitis, inflammation, or exudate on cervical smears tests and confirmed presence of known cervical pathogens. | 1993 | 8499824 |
| in vitro activity of fk037, a new parenteral cephalosporin, against anaerobic bacteria. | the activity of fk037, a new parenteral cephalosporin, was compared with those of cefpirome, ceftazidime, and flomoxef against 322 recent clinical isolates of anaerobic bacteria. a fastidious facultative anaerobe, gardnerella vaginalis, was also studied. fk037 inhibited 90% of isolates of peptostreptococcus anaerobius, peptostreptococcus asaccharolyticus, clostridium perfringens, mobiluncus spp., g. vaginalis, and porphyromonas gingivalis at < or = 0.78 micrograms/ml. the mics of fk037 for 50 an ... | 1993 | 8517721 |
| antimicrobial susceptibilities of gardnerella vaginalis. | the in vitro susceptibilities of 93 clinical isolates of gardnerella vaginalis to 25 antimicrobial agents were determined by the agar dilution method. all isolates were susceptible to penicillin, ampicillin, erythromycin, clindamycin, chloramphenicol, and trimethoprim. activity was poor for vancomycin, ly146032, the cephalosporins, ciprofloxacin, and imipenem. some resistance was observed with tetracycline and minocycline. the mics of metronidazole paralleled those of tinidazole, with the hydrox ... | 1993 | 8109944 |
| [sexually transmitted diseases (stds) in a group of adolescents attending a perinatal care institute]. | to start an active sexual activity at an earlier age and with a larger number of partners, has arousen the frequency of sexually transmitted diseases (sts). the teenagers are a group particularly affected. the objective of this article is to report the etiology of std in a group of teenagers, out-patients at the instituto nacional de perinatologia (inper). the study includes 1360 patients at the clinic of std at the inper, 8.5 percent were less than 20 years old; 18.9 percent of them had previou ... | 1993 | 8063080 |
| [a trial of the use of diflucan (fluconazole) in patients with vaginal candidiasis]. | fifty females with vaginitis due to candida albicans were treated with fluconazol (diflucan) in a single dose of 150 mg administered per os. a complete elimination of the clinical signs in 42 out of 50 patients (84 per cent) and a significant improvement of the clinical picture in 4 out of 50 patients (8 per cent) were recorded. the cultures of the smears produced no fungal growth with respect to 31 out of 36 patients (86.1 per cent), while microscopically the presence of the fungus with the sig ... | 1993 | 8085908 |
| comparative in-vitro activities of the new quinolone, bay y 3118, and ciprofloxacin, sparfloxacin, tosufloxacin, ci-960 and ci-990. | the in-vitro activity of the new quinolone, bay y 3118, was compared with that of ciprofloxacin, tosufloxacin, sparfloxacin, ci-960 and ci-990 against 1640 isolates belonging to 117 bacterial species. against members of the enterobacteriaceae, bay y 3118 was as active as ci-960 and ci-990, up to four-fold more active than ciprofloxacin and tosufloxacin and up to 16-fold more active than sparfloxacin. the majority of enterobacteriaceae which were resistant to ciprofloxacin (mics > or = 2 mg/l) we ... | 1993 | 7605398 |
| isolation of chlamydia trachomatis among women with symptoms of lower genital tract infection. | isolation of chlamydia trachomatis from the endocervix using cyclohexamide-treated mccoy cells were done in order to estimate the prevalence rate of its infection among gynecologic out patients who had symptoms and/or signs of lower genital tract infection. there were 498 patients from may 1989 to july 1990. eighty-six per cent of these patients were 25 years old or older. most of them (63%) were agricultural employees. ninety-three per cent were married and 78 per cent had less than or equal to ... | 1993 | 7964252 |
| pore-forming and haemolytic properties of the gardnerella vaginalis cytolysin. | the pleomorphic bacterium gardnerella vaginalis releases in the culture broth a haemolytic exotoxin (gvh) which is probably a virulence determinant of this unique bacterium, implicated in gynaecological and urological disorders. this 59 kda cytolysin was purified to homogeneity in just one chromatographic step directly from the culture supernatant, a final specific activity up to 1.9 x 10(6) hu mg-1 being obtained. the toxin-induced lesion on human erythrocytes results from the formation of a po ... | 1993 | 7934928 |
| bacterial vaginosis associated with g vaginallis / mobiluncus sp: ultrastructural parameters. | physicians at the national institute of perinatology in mexico city, mexico used a carl-zeiss em 10c electron microscope to examine genital secretion samples from 10 pregnant women (15-38 weeks' gestation) who had been diagnosed with mobiluncus species and gardnerella vaginalis infections to illustrate the form and structure of bacteria responsible for bacterial vaginosis. they were concerned that these bacteria induce preterm labor and premature rupture of membranes (pl/prom). these bacteria ... | 1992 | 12317783 |
| isolation of gardnerella vaginalis from the genital tract of six mares. | 1992 | 17424118 | |
| the relationship of hydrogen peroxide-producing lactobacilli to bacterial vaginosis and genital microflora in pregnant women. | lactobacilli provide an important microbial defense against genital colonization by pathogens. the role of hydrogen peroxide (h2o2) in the control of genital microflora was explored in a cross-sectional study of 275 women in the second trimester of pregnancy. vaginal cultures were obtained for detection of h2o2-positive and h2o2-negative lactobacilli and other members of the genital microflora. compared with women with h2o2-negative lactobacilli, women colonized by h2o2-positive lactobacilli wer ... | 1992 | 1738516 |
| microbiological diagnosis of bacterial vaginosis. | 1992 | 1282150 | |
| the cervical papanicolaou smear: bacterial infection and the bethesda system. | 1992 | 1282151 | |
| [the use of the direct method for the diagnosis of gardnerella vaginalis vaginitis]. | a study was carried out on 200 patients divided in two groups of 100, labeled 1 and 2. they underwent vaginal secretion tests by the direct method in order to assess its appropriateness for gardnerella vaginalis presumptive diagnosis. this study was related with patients' symptoms, such as leukorrhea and fetidity prevailing in group 1 and lower abdomen pain prevailing in group 2, as well as the proportions of germs isolated and the association with this symptom for defining the microorganism rol ... | 1992 | 1295010 |
| antibacterial activity in vitro of cefpirome against clinical isolates causing sexually transmitted diseases. | the in-vitro activity of cefpirome was compared with other antibiotics against organisms causing sexually transmitted diseases (std). the excellent activity of cefpirome against neisseria gonorrhoeae (mic90 1.0 mg/l), haemophilus ducreyi (mic90 0.5 mg/l), and gardnerella vaginalis (mic90 1.0 mg/l) suggests that this agent might be useful in the empirical treatment of a variety of venereal diseases. | 1992 | 1318294 |