Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| experimental mycobacteriosis in striped bass morone saxatilis. | striped bass morone saxatilis were infected intraperitoneally with approximately 10(5) mycobacterium marinum, m. shottsii sp. nov., or m. gordonae. infected fish were maintained in a flow-through freshwater system at 18 to 21 degrees c, and were examined histologically and bacteriologically at 2, 4, 6, 8, 17, 26, 36 and 45 wk post-infection (p.i.). m. marinum caused acute peritonitis, followed by extensive granuloma development in the mesenteries, spleen and anterior kidney. granulomas in these ... | 2003 | 12747636 |
| drosophila melanogaster is a genetically tractable model host for mycobacterium marinum. | mycobacterium marinum is a pathogenic mycobacterial species that is closely related to mycobacterium tuberculosis and causes tuberculosis-like disease in fish and frogs. we infected the fruit fly drosophila melanogaster with m. marinum. this bacterium caused a lethal infection in the fly, with a 50% lethal dose (ld(50)) of 5 cfu. death was accompanied by widespread tissue damage. m. marinum initially proliferated inside the phagocytes of the fly; later in infection, bacteria were found both insi ... | 2003 | 12761139 |
| intracellular replication of mycobacterium marinum within dictyostelium discoideum: efficient replication in the absence of host coronin. | mycobacterium marinum causes tuberculosis-like disease in fish and amphibians and has been used as a model mycobacterial species because of its rapid growth and less stringent containment requirements relative to other mycobacterial species. we demonstrate here that m. marinum grows within dictyostelium discoideum cells, allowing the genetic analysis of host factors that may modulate the replication of mycobacterial species. intracellular growth of m. marinum was shown to mimic the properties pr ... | 2003 | 12761143 |
| [bothersome nodules on the fingers of a musician]. | 2003 | 12762204 | |
| [cutaneous nodules to an aquarist]. | 2003 | 12763180 | |
| mycobacterium marinum infections of the distal upper extremities: clinical course and imaging findings in two cases with delayed diagnosis. | mycobacterium marinum infections cause tenosynovitis of the distal upper extremities and develop as a consequence of skin abrasions acquired in contaminated water. we report on two patients whose mr imaging studies showed tenosynovitis of the distal upper extremity secondary to m. marinum. in one patient sequential mr imaging showed development of bony erosions. appropriate treatment was delayed in both patients because the diagnosis was not considered. we report on and discuss the clinical cour ... | 2003 | 12774175 |
| decolorization of malachite green and crystal violet by waterborne pathogenic mycobacteria. | mycobacterium avium, mycobacterium intracellulare, mycobacterium scrofulaceum, mycobacterium marinum, and mycobacterium chelonae tolerate high concentrations of the dyes malachite green and crystal violet. cells of strains of those species decolorized (reduced) both malachite green and crystal violet. because decolorized malachite green lacked antimicrobial activity, the resistance of these mycobacteria could be due, in part, to their ability to decolorize the dyes. small amounts of malachite gr ... | 2003 | 12821489 |
| [tropical fish salesmen's knowledge and behaviour concerning "fish tank granuloma"]. | mycobacterium marinum is responsible for "fish tank granuloma", a chronic and sometimes disabling skin infection, which in france would be the most frequent "atypical" cutaneous mycobacteriosis. tropical fish salesmen are concerned about this disease because they might sell contaminated fish and be infected themselves. a review of the literature indicated that one quarter of the patients were aquarium workers. this original study tested the salesmen's knowledge and behaviour regarding "fish tank ... | 2003 | 12843853 |
| [wrong diagnosis in the case of skin nodules in a musician?]. | 2003 | 12868364 | |
| [granulomatous skin disease after an exotic injury]. | piranhas are feared freshwater fishes commonly found in the waters of southern venezuela to the north of argentina. at present this species is a favourite domesticated article of our aquarists. the authors describe the histopathologic picture of a cutaneous lesion of the right hand thumb of a 60-year old piranha keeper who was bitten by this predatory fish. a firm node with increasing soreness gradually developed in the area of the lesion, and after 7 months the symptoms of the carpal tunnel syn ... | 2003 | 12874906 |
| a prolonged case of mycobacterium marinum flexor tenosynovitis: radiographic and histological correlation, and review of the literature. | we report on a 30-year-old man with prolonged mycobacterium marinum flexor tenosynovitis. due to low clinical suspicion, diagnosis was not made until 8 years after initial presentation. the history and magnetic resonance and tissue examination findings are consistent with mycobacterial tenosynovitis. these findings are presented, together with a review of the literature. | 2003 | 12879295 |
| fish tank exposure and cutaneous infections due to mycobacterium marinum: tuberculin skin testing, treatment, and prevention. | in the present study, 8 patients with soft tissue infection due to mycobacterium marinum are described, and contemporary data on treatment are reviewed. six patients had positive cultures, all patients had cutaneous exposure to fish tanks, 7 had sporotrichoid lesions, and 2 had deep infection. all 7 tested patients had tuberculin skin test reactions > or =10 mm. six patients with disease limited to the skin were successfully treated with 2-drug combination therapy, including clarithromycin, etha ... | 2003 | 12884164 |
| biofilm formation and biocide susceptibility testing of mycobacterium fortuitum and mycobacterium marinum. | the ability of non-tuberculous mycobacteria to form biofilms may allow for their increased resistance to currently used biocides in medical and industrial settings. this study examines the biofilm growth of mycobacterium fortuitum and mycobacterium marinum, using the mbec trade mark assay system, and compares the susceptibility of planktonic and biofilm cells to commercially available biocides. with scanning electron microscopy, both m. fortuitum and m. marinum form biofilms that are morphologic ... | 2003 | 12432460 |
| mycobacteriosis in two captive florida manatees (trichechus manatus latirostris). | two male florida manatees (trichechus manatus latirostris) died at the marine aquarium in inagi city, tokyo, japan. acid-fast bacteria were demonstrated in tuberculoid nodules in the lungs from both manatees. mycobacterium marinum and m. fortuitum were isolated from one manatee; m. marinum and m. kansasii were cultured from the second animal. this report confirms the pathogenicity and potentially fatal outcome of mycobacterial infection in manatees. in addition, the pathologic response to infect ... | 2003 | 12885137 |
| requirement for kasb in mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy. | mycobacterium tuberculosis infects one-third of the world's population and causes two million deaths annually. the unusually low permeability of its cell wall contributes to the ability of m. tuberculosis to grow within host macrophages, a property required for pathogenesis of infection. mycobacterium marinum is an established model for discovering genes involved in mycobacterial infection. mycobacterium marinum mutants with transposon insertions in the beta-ketoacyl-acyl carrier protein synthas ... | 2003 | 12950920 |
| zebrafish-mycobacterium marinum model for mycobacterial pathogenesis. | we report here the development of a pathogenesis model utilizing mycobacterium marinum infection of zebrafish (danio rerio) for the study of mycobacterial disease. the zebrafish model mimics certain aspects of human tuberculosis, such as the formation of granuloma-like lesions and the ability to establish either an acute or a chronic infection based upon inoculum. this model allows the genetics of mycobacterial disease to be studied in both pathogen and host. | 2003 | 12951238 |
| mycobacterium marinum infection in connecticut: report of four cases. | mycobacterium marinum is emerging as an important human pathogen in the united states. we report four cases incidentally diagnosed from culture of biopsy specimens of wrist lesions at a connecticut inner city hospital between 1996 and 1999. there was no clear association with aquatic exposure and only one patient recalled prior trauma. all were successfully treated with ethambutol and rifampicin. the current literature on the epidemiology, clinical characteristics and management of mycobacterium ... | 2003 | 12956043 |
| transforming growth factor-beta response to mycobacterial infection in striped bass morone saxatilis and hybrid tilapia oreochromis spp. | striped bass (morone saxatilis) and hybrid tilapia (oreochromis spp.) were experimentally infected with mycobacterium marinum. splenic mononuclear cell transforming growth factor-beta (tgf-beta) mrna was measured by reverse transcription quantitative-competitive pcr (rt-qcpcr). in histologic sections of liver and anterior kidney, the area of each section that was occupied by granulomas and the total area of each section were measured by computer-assisted image analysis and compared as a proporti ... | 2003 | 12963276 |
| a recombinant vaccine expressing a mammalian mycobacterium sp. antigen is immunostimulatory but not protective in striped bass. | a recombinant vaccine was constructed for piscine mycobacteriosis utilizing a brucella abortus strain rb51 vector expressing a mammalian mycobacterium sp. 85a antigen. juvenile striped bass were inoculated with the resulting construct at doses equivalent to 10(6), 10(7), 10(8), 10(9), and 10(10) colony-forming units/fish. blood and tissue samples from these fish demonstrated significant specific humoral and cell-mediated immune responses towards the 85a antigen in a dose-dependent manner. howeve ... | 2003 | 12969635 |
| skin tuberculosis with atypical mycobacteria 8 years after combined pancreas-kidney transplantation. | we report on a mycobacterium marinum infection in a diabetic woman 8 years after undergoing a combined pancreas-kidney transplantation. this is, to our knowledge, the first case report on an isolated skin infection with atypical mycobacteria after simultaneous pancreas-kidney transplantation. a genetic probe categorization revealed an infection with m. marinum. skin tuberculosis caused by m. marinum is an uncommon complication in kidney or pancreas-kidney transplant recipients, hence the diagnos ... | 2002 | 12381960 |
| strain variation in mycobacterium marinum fish isolates. | a molecular characterization of two mycobacterium marinum genes, 16s rrna and hsp65, was carried out with a total of 21 isolates from various species of fish from both marine and freshwater environments of israel, europe, and the far east. the nucleotide sequences of both genes revealed that all m. marinum isolates from fish in israel belonged to two different strains, one infecting marine (cultured and wild) fish and the other infecting freshwater (cultured) fish. a restriction enzyme map based ... | 2002 | 12406715 |
| tuberculin skin testing and in vitro t cell responses to esat-6 and culture filtrate protein 10 after infection with mycobacterium marinum or m. kansasii. | t cell responses to esat-6 and culture filtrate protein 10 (cfp-10), antigens expressed by mycobacterium tuberculosis but not by m. bovis bacille calmette-guérin (bcg), were found to discriminate reliably between infection with m. tuberculosis and bcg vaccination. because the esat-6 and cfp-10 genes occur in m. kansasii and m. marinum, t cell responses to esat-6 and cfp-10 were investigated in patients infected with m. kansasii or m. marinum, persons intensively exposed to environmental mycobact ... | 2002 | 12447766 |
| disseminated cutaneous mycobacterium marinum infection in a patient with non-hodgkin's lymphoma. | a 60-year-old woman with non-hodgkin's lymphoma was admitted to the hospital because of extensive subcutaneous abscesses developing on all limbs. the patient had an aquarium and kept tropical fish as pets. after repeated investigations, the diagnosis of mycobacterium marinum was established from skin biopsy by pcr and culture. long-term therapy with several drugs regimens had only a limited efficacy and was accompanied by severe adverse reactions. this report highlights the therapeutic problems ... | 2002 | 12478331 |
| real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos. | infection of vertebrate hosts with pathogenic mycobacteria, the agents of tuberculosis, produces granulomas, highly organized structures containing differentiated macrophages and lymphocytes, that sequester the pathogen. adult zebrafish are naturally susceptible to tuberculosis caused by mycobacterium marinum. here, we exploit the optical transparency of zebrafish embryos to image the events of m. marinum infection in vivo. despite the fact that the embryos do not yet have lymphocytes, infection ... | 2002 | 12479816 |
| mycobacterium lacus sp. nov., a novel slowly growing, non-chromogenic clinical isolate. | a strain of a novel non-chromogenic mycobacterium was isolated from synovial tissue from a 68-year-old female with bursitis of her right elbow. the slowly growing strain had a unique pcr-restriction enzyme analysis (pra) profile of the hsp65 gene and 16s rrna gene sequence in comparison with other mycobacterium species. the most closely related species, as determined by 16s rrna gene sequence analysis, are mycobacterium malmoense, mycobacterium marinum, mycobacterium ulcerans and members of the ... | 2002 | 12508880 |
| mycobacterial infection in farmed turbot scophthalmus maximus. | mycobacteriosis (piscine tuberculosis) has been reported to affect a wide range of freshwater and marine fish species; however, this is the first report describing mycobacterial infections in turbot scophthalmus maximus. high numbers of granulomas were initially observed in the organs of moribund farmed turbot. bacteriological analysis of organs with granulomas led to the isolation of mycobacterium marinum. further analysis, to determine the prevalence of the infection in the farm and to identif ... | 2002 | 12517009 |
| [mycobacterium marinum infection]. | 2002 | 12522903 | |
| efficacy of oral minocycline and hyperthermic treatment in a case of atypical mycobacterial skin infection by mycobacterium marinum. | we report a case of atypical mycobacterial dermal infection caused by m. marinum, which was effectively treated with oral administration of minocycline and local hyperthermic treatment using chemical pocket warmers. a daily oral dose of 200 mg of minocycline was given, and local hyperthermic treatment was applied every evening for 5-6 hours with a disposable chemical pocket warmer. after 2.5 months of therapy, the lesion healed completely with scar formation. at 24 months after the completion of ... | 2002 | 12532049 |
| [pulmonary mycobacterioses--frequency of occurrence, clinical spectrum and predisposing factors]. | various types of non-tuberculous mycobacteria can be the aetiologic factors of chronic lung infections especially in patients with underlying chronic lung diseases. the aim of this study is to present the cases of pulmonary mycobacterioses observed in institute of tuberculosis and lung diseases in the years 1995-2001. there were 23 patients, 12 men and 11 women in the age between 35-77 years, mean 56 years. 16 out of 23 patients had underlying respiratory problems, mainly healed tuberculosis (7) ... | 2002 | 12884564 |
| in vitro activity of 11 antimicrobial agents, including gatifloxacin and gar936, tested against clinical isolates of mycobacterium marinum. | in vitro activities of 11 antimicrobial agents were determined using etest (ab biodisk, solna, sweden) against 37 clinical isolates of mycobacterium marinum. the most potent agent (mic(50,) 0.047 microg/ml) was trimethoprim/sulfamethoxazole, but only 91.9% would be categorized as susceptible. several agents had a complete spectrum of activity including gatifloxacin (mic(90,) 0.38 microg/ml), minocycline (mic(90,) 2 microg/ml), tetracycline (mic(90,) 2 microg/ml) and amikacin (mic(90,) 3 microg/m ... | 2002 | 11858912 |
| complex pattern of mycobacterium marinum gene expression during long-term granulomatous infection. | during latent infection of humans with mycobacterium tuberculosis, bacteria persist in the asymptomatic host within granulomas, organized collections of differentiated macrophages, and other immune cells. the mechanisms for persistence remain poorly understood, as is the metabolic and replicative state of the microbes within granulomas. we analyzed the gene expression profile of mycobacterium marinum, the cause of fish and amphibian tuberculosis, during its persistence in granulomas. we identifi ... | 2002 | 11891270 |
| susceptibilities of mycobacterium marinum to gatifloxacin, gemifloxacin, levofloxacin, linezolid, moxifloxacin, telithromycin, and quinupristin-dalfopristin (synercid) compared to its susceptibilities to reference macrolides and quinolones. | the susceptibility pattern of mycobacterium marinum was determined. quinupristin-dalfopristin and telithromycin were less active than clarithromycin. linezolid showed good antimicrobial activity at clinically achievable concentrations. gatifloxacin, levofloxacin, and moxifloxacin displayed activities similar to those of ciprofloxacin. gemifloxacin was less active. the etest method showed variable agreement with the reference method. | 2002 | 11897601 |
| [skin nodules and ulcers of the limbs in a patient with rheumatoid arthritis]. | while being treated with corticosteroids and methotrexate for rheumatoid arthritis, a 63-year-old man developed livid nodules on his lower arms, hands and feet, as well as fever, necrotizing skin ulcers and rupture of a finger extensor tendon. | 2002 | 11935470 |
| mycobacterium marinum infection in taiwan. | mycobacterium marinum often causes skin infections, tenosynovitis, arthritis, and osteomyelitis, and occasionally results in severe disseminated infections in immunocompromised patients. in this study, the clinical features of 14 cases of m. marinum infection were retrospectively analyzed. one patient had septic arthritis, the other 13 had skin infections and/or tenosynovitis. it usually took 2 months or longer for a definite diagnosis to be made in these patients. three of the 14 patients were ... | 2002 | 11950119 |
| pulmonary mycobacteriosis caused by mycobacterium haemophilum and m. marinum in a royal python. | an adult female royal python was referred with an 18-month history of chronic respiratory tract disease. anemia and moderate leukocytosis with heterophilia and monocytosis were detected and interpreted as evidence of a chronic inflammatory condition. evaluation of lateral and dorsoventral radiographic views revealed multiple soft-tissue opacities within the cranial lung fields. endoscopic evaluation revealed that the normal reticulated pattern on the surface of the lung had been largely replaced ... | 2002 | 12051506 |
| characterization of an unusual mycobacterium: a possible missing link between mycobacterium marinum and mycobacterium ulcerans. | in an attempt to characterize an unusual mycobacterial isolate from a 44-year-old patient living in france, we applied phenotypic characterizations and various previously described molecular methods for the taxonomic classification of mycobacteria. the results of the investigations were compared to those obtained in a previous study with a set of temporally and geographically diverse mycobacterium ulcerans (n = 29) and mycobacterium marinum (n = 29) isolates (k. chemlal, g. huys, p.-a. fonteyne, ... | 2002 | 12089250 |
| diverse bacteria are pathogens of caenorhabditis elegans. | practically and ethically attractive as model systems, invertebrate organisms are increasingly recognized as relevant for the study of bacterial pathogenesis. we show here that the nematode caenorhabditis elegans is susceptible to a surprisingly broad range of bacteria and may constitute a useful model for the study of both pathogens and symbionts. | 2002 | 12117988 |
| sixty-three cases of mycobacterium marinum infection: clinical features, treatment, and antibiotic susceptibility of causative isolates. | mycobacterium marinum is a nontuberculous mycobacterium responsible for skin infections. although cases have been seldom reported, no series of m marinum infection has been recently reported and the treatment is not standardized. | 2002 | 12153378 |
| strain variation in mediterranean and red sea mycobacterium marinum isolates. | four different pcr fingerprinting techniques were tested to distinguish possible strain variations in fourteen mycobacterium marinum isolates, thirteen from mediterranean and red sea fishes and one from a patient in sardinia, italy. pcr ribotyping and eric (enterobacterial repetitive consensus sequences)-pcr were found to be non-discriminative, whereas is (insertion sequences)-pcr and gtg (gtg sequences repeats)-pcr could distinguish the clinical isolate from the piscine isolates, two italian pi ... | 2002 | 12173779 |
| persistent ulcers on the hand of an aquarium owner. | we present a patient with skin ulcers that did not respond to a 3-week course of treatment with amoxicillin-clavulanic acid. as the patient maintained a fish aquarium, mycobacterial infection was suspected. indeed, reassessment of histopathology revealed acid-fast bacilli, and mycobacterial cultures at 30 degrees c grew mycobacterium marinum. eventually, surgical reconstruction of the tendons was needed. | 2002 | 12238586 |
| nostril infection due to mycobacterium marinum in an immunocompetent host. | mycobacterium marinum infection developed in the nostril of an immunocompetent host whose only risk factors were infrequent swimming and cleaning of a small fish bowl on a single occasion. the lesion relapsed after 2 surgical excisions but resolved slowly with a 9-month course of trimethoprim/sulfa therapy. | 2002 | 12587630 |
| mycobacterium marinum tenosynovitis in a patient on etanercept therapy for rheumatoid arthritis. | opportunistic infections are a theoretical concern with the use of tumor necrosis factor antagonists, as these agents can impair host immunity. a 61-year-old man with rheumatoid arthritis being treated with only etanercept (soluble tumor necrosis factor receptor) and in remission from the rheumatoid arthritis presented with dorsal tenosynovitis of his right wrist. the synovitis was not improved by a local corticosteroid injection. surgical exploration showed granulomatous inflammation, and cultu ... | 2002 | 17041383 |
| [lymphocutaneous syndrome due to mycobacterium marinum in a young aquarium enthusiast]. | 2001 | 11844463 | |
| case report--slowly enlarging mass of the dorsal right hand in a pregnant woman. | 2001 | 11965202 | |
| [nontuberculous mycobacterial infections]. | 2001 | 11977501 | |
| detection of a new mycobacterium species in wild striped bass in the chesapeake bay. | investigation into recent declines in striped bass health in the chesapeake bay in maryland resulted in the isolation of a putative new species of mycobacterium. this isolate was obtained from fish showing skin ulcers and internal granulomas in various organs. the isolate was slow growing at 28 degrees c; was nonchromogenic; showed no activities of nitrate reduction, catalase activity, tween 80 hydrolysis, tellurite reduction, or arylsulfatase reduction; grew best at low salt concentrations; and ... | 2001 | 11158132 |
| production of a species specific monoclonal antibody against a 56-kda mycobacterium marinum antigen which is potentially useful in culture identification. | a monoclonal antibody (moab) designated 1h11 has been produced against a 56-kda antigen from mycobacterium marinum. this moab has been shown to be species specific by both enzyme-linked immunosorbent assay and western blot. the relationship of this 56 kda to other known mycobacterial antigens is currently under investigation. moab 1h11 recognised bacilli taken from cultures by both immunofluorescence and immunoperoxidase staining. this moab 1h11 may provide a simple method for rapid identificati ... | 2001 | 11172985 |
| sporotrichoid lymphocutaneous infections: etiology, diagnosis and therapy. | sporotrichoid lymphocutaneous infection is an uncommon syndrome that is often misdiagnosed and improperly treated. of the several hundred cases seen each year in the united states, the majority are caused by sporothrix schenckii, nocardia brasiliensis, mycobacterium marinum or leishmania brasiliensis. the "sporotrichoid" disease begins at a site of distal inoculation and leads to the development of nodular lymphangitis. systemic symptoms are characteristically absent. by recognizing the distinct ... | 2001 | 11201697 |
| mycobacterium marinum hand infection. | 2001 | 11207141 | |
| multicenter study of incidence of mycobacterium marinum in humans in spain. | a retrospective survey was carried out on the epidemiological monitoring of the isolation incidence of mycobacterium marinum in 21 laboratories, in an attempt to gain an insight into the frequency of its isolation in spain. from 1991 to 1998, 39 cases (22 male and 17 female) of bacteriologically confirmed m. marinum infection were accumulated. the majority of the cases (35) were fish related. the clinical presentation usually suggested sporotrichosis, with the majority of skin eruptions appearin ... | 2001 | 11258515 |
| mycobacterial infections in domestic and wild animals due to mycobacterium marinum, m. fortuitum, m. chelonae, m. porcinum, m. farcinogenes, m. smegmatis, m. scrofulaceum, m. xenopi, m. kansasii, m. simiae and m. genavense. | the epidemiology and the natural distribution of mycobacterium marinum, m. fortuitum, m. chelonae, m. porcinum, m. farcinogenes, m. smegmatis, m. scrofulaceum, m. xenopi, m. kansasii, m. simiae and m. genavense are described. in addition to the bacteriological, biochemical and genetic characteristics, the authors review the pathology of these species, including the natural and experimental diseases and the accompanying lesions, diagnosis, antibiotic sensitivities and treatment of animal infectio ... | 2001 | 11288516 |
| mycobacterium marinum infection in a lung transplant recipient. | we report a case of mycobacterium marinum infection in a lung transplant recipient who presented with nodules on the hand and forearm following exposure to fish-tank water of a superficial hand burn. skin biopsy revealed granulomatous inflammation and fibrosis. tissue culture grew mycobacterium marinum. the patient underwent surgical excision of the lesions and treatment with ethambutol and azithromycin for 12 months and experienced complete resolution of the infection. transplant recipients who ... | 2001 | 11295588 |
| a case of disseminated mycobacterium marinum infection following systemic steroid therapy. | we describe the dissemination of mycobacterium marinum infection from the right middle finger to the whole extremity and two legs, with the involvement of tendons and joints, in a patient who was treated with a steroid when mycobacterium marinum infection was not suspected. the patient was successfully treated with a combined surgical and medical approach. | 2001 | 11303818 |
| unusual and memorable. a tender swelling of the dorsum of a hand in a middle aged woman. | 2001 | 11350842 | |
| sporotrichoid lymphangitis due to group a streptococcus. | we describe what is, to our knowledge, the first case of sporotrichoid lymphangitis caused solely by group a streptococcus in an otherwise healthy patient. infection with pyogenic pathogens, such as streptococci and staphylococci, as well as with the most common causes of sporotrichoid lymphangitis (i.e., sporothrix schenkii, nocardia brasiliensis, mycobacterium marinum, and leishmania species) should be considered in differential diagnosis for some patients. | 2001 | 11360227 |
| identification of mycobacterium marinum in sea-urchin granulomas. | sea-urchin granuloma is a chronic granulomatous reaction arising after injury with sea-urchin spines. classified as an allergic foreign-body type of granuloma, it is believed to be a delayed-type reaction to an as yet unidentified antigen. in a clinicopathological study, 50 biopsy specimens from 35 patients diagnosed as having sea-urchin granuloma caused by paracentrotus lividus, we found different inflammatory patterns that in some cases suggested a mycobacterial infection. | 2001 | 11453918 |
| the use of is2404 restriction fragment length polymorphisms suggests the diversity of mycobacterium ulcerans from different geographical areas. | buruli ulcer, caused by mycobacterium ulcerans, has been reported in five continents: africa, asia, australia, and north and south america. in the present study, restriction fragment length polymorphism with the recently described m. ulcerans specific insertion sequence is2404 as a probe, was applied to mycobacterium shinshuense, mycobacterium marinum, and 14 clinical m. ulcerans isolates originating from six geographic areas: africa (n = 6), australia (n = 2), mexico (n = 1), south asia (n = 2) ... | 2001 | 11463115 |
| antimicrobial susceptibility of mycobacterium marinum determined by e-test and agar dilution. | mycobacterium marinum is recognized as a cutaneous pathogen requiring antibiotic treatment. we compared the e-test with a reference agar dilution method for susceptibility testing of m. marinum to amikacin, ciprofloxacin, clarithromycin, doxycycline, rifampicin, trimethoprim-sulfamethoxazole and ethambutol. mics obtained after 6 d showed agreement between the e-test and agar dilution within +/- 2 dilutions in 95% of all cases for amikacin, ciprofloxacin, doxycycline and rifampicin. inhibitory co ... | 2001 | 11525351 |
| evaluation of pcr-restriction profile analysis and is2404 restriction fragment length polymorphism and amplified fragment length polymorphism fingerprinting for identification and typing of mycobacterium ulcerans and m. marinum. | mycobacterium ulcerans and m. marinum are emerging necrotizing mycobacterial pathogens that reside in common reservoirs of infection and exhibit striking pathophysiological similarities. furthermore, the interspecific taxonomic relationship between the two species is not clear as a result of the very high phylogenetic relatedness (i.e., >99.8% 16s rrna sequence similarity), in contrast to only 25 to 47% dna relatedness. to help understand the genotypic affiliation between these two closely relat ... | 2001 | 11526162 |
| production of selenomethionine-labelled proteins using simplified culture conditions and generally applicable host/vector systems. | the amino acid analogue selenomethionine (semet) is shown to be efficiently incorporated into recombinant proteins expressed in escherichia coli grown in a simple minimal medium without the addition of synthetic amino acids. furthermore, satisfactory semet incorporation is obtained with a methionine-prototrophic strain transformed with commonly used vector systems. as examples, purified tryparedoxin 1 from crithidia fasciculata, alkylhydroperoxide reductase (ahpc) from mycobacterium marinum and ... | 2001 | 11601620 |
| rapid identification of cutaneous infections by nontubercular mycobacteria by polymerase chain reaction-restriction analysis length polymorphism of the hsp65 gene. | nontubercular mycobacteria (ntm) may cause cutaneous infections which are difficult to interpret due to the variability of the clinical manifestations. this study involved eight patients (four men and four women) with primary cutaneous infections caused by ntm; the skin lesions included dermo-hypodermal abscesses, suppurative granulomas, and papulonodules localized on the legs, arms, hands, and face. the general condition of the patients was relatively good and they were not immunosuppressed. | 2001 | 11703519 |
| fish monocytes as a model for mycobacterial host-pathogen interactions. | mycobacterium marinum, a relatively rapid-growing fish and human pathogen, has become an important model for the investigation of mycobacterial pathogenesis. m. marinum is closely related to the mycobacterium tuberculosis complex and causes a disease in fish and amphibians with pathology similar to tuberculosis. we have developed an in vitro model for the study of m. marinum virulence mechanisms using the carp monocytic cell line clc (carp leukocyte culture). we found that fish monocytes can dif ... | 2001 | 11705902 |
| dynamic nature of host-pathogen interactions in mycobacterium marinum granulomas. | mycobacterium marinum causes long-term subclinical granulomatous infection in immunocompetent leopard frogs (rana pipiens). these granulomas, organized collections of activated macrophages, share many morphological features with persistent human tuberculous infection. we examined organs of frogs with chronic m. marinum infection using transmission electron microscopy in conjunction with immunohistochemistry and acid phosphatase cytochemistry to better define the bacterium-host interplay during p ... | 2001 | 11705964 |
| mycobacterium marinum dermatitis and panniculitis with chronic pleuritis in a captive white whale (delphinapterus leucas) with aortic rupture. | a 16-year-old female white whale, delphinapterus leucas, died after nearly 18 months of chronic lymphopenia and pyogranulomatous dermatitis. necropsy revealed rupture of the aorta with hemorrhage into the cranial mediastinum and between fascial planes of the ventral neck musculature. multiple foci of ulcerative dermatitis and panniculitis were present across the thorax and abdomen and surrounded the genital folds. in addition, there was a chronic proliferative pleuritis with over 20 liters of hi ... | 2001 | 11724146 |
| a unique mycobacterium species isolated from an epizootic of striped bass (morone saxatilis). | we isolated a mycobacterium sp. resembling mycobacterium marinum and m. ulcerans from diseased striped bass (morone saxatilis) during an epizootic of mycobacteriosis in the chesapeake bay. this isolate may represent an undescribed mycobacterium species, based on phenotypic characteristics and comparative 16s rrna gene sequence. | 2001 | 11747708 |
| mycobacterium marinum tenosynovitis in a patient with still's disease. | 2001 | 11752518 | |
| a promoter probe plasmid based on green fluorescent protein : a strategy for studying meningococcal gene expression. | many bacterial genes are regulated in an environment-responsive fashion, and from the perspective of a pathogen, the host represents just another environment. many genes that contribute to virulence are differentially expressed in response to host environments that they encounter during colonization and invasion (1). recognition of this has led to the development of selection or reporter systems that utilize the increased activity of promoters during growth in vivo to identify genes that are sel ... | 2001 | 21337172 |
| activation of cutaneous sarcoidosis following mycobacterium marinum infection of skin. | sarcoidosis has long been associated with mycobacterial infection, especially with mycobacterium tuberculosis, although a causal association has not been proven. atypical mycobacteria have also been implicated in causing sarcoidosis, but there is as yet no conclusive evidence. we report the activation of cutaneous sarcoidosis following infection with m. marinum, raising further questions about the role of these bacteria in causing this chronic granulomatous disorder. | 2000 | 11204520 |
| analysis by enzyme-linked immunosorbent assay and immunoblot of the antibody responses of patients infected with mycobacterium marinum. | the serum antibody responses of a total of 14 patients with active or recently cured mycobacterium marinum infections were analysed via a combination of enzyme-linked immunosorbent assay (elisa) and the immunodevelopment of western blots of m. marinum antigen. normal human sera and sera from patients with active pulmonary tuberculosis were also analysed as controls. the detectable igg response of m. marinum patients, as demonstrated by elisa, was highly variable and did not differ significantly ... | 2000 | 10683462 |
| transformation and transposition of the genome of mycobacterium marinum. | to develop and evaluate protocols for genetic manipulations (transformation and transposition) of the fish pathogen, mycobacterium marinum. | 2000 | 10685681 |
| [clinical presentation and therapy of mycobacterium marinum infection as seen in 12 cases]. | mycobacterium marinum (m.m.) is the causative pathogen of skin infections that have been called "swimming pool granulomas". an increasing number of reports that deep structures are involved in these infections was the reason for studying the clinical presentation and response of the infection to different therapeutic regimens. | 2000 | 10650818 |
| [cutaneous sporotricoid infection by mycobacterium marinum]. | 2000 | 10721568 | |
| cutaneous infections due to nontuberculous mycobacteria: histopathological review of 28 cases. comparative study between lesions observed in immunosuppressed patients and normal hosts. | to evaluate the histopathological features observed in patients with cutaneous infections due to nontuberculous mycobacteria (ntm) and to compare the histopathological patterns observed in immunosuppressed patients and normal hosts. twenty-eight biopsy specimens corresponding to 27 patients with cutaneous infections due to ntm were reviewed. eighteen biopsies corresponded to normal hosts (14 mycobacterium marinum, 2 mycobacterium chelonae, 1 mycobacterium terrae and 1 mycobacterium gordonae) and ... | 2000 | 10728814 |
| mycobacteriosis in wild rabbitfish siganus rivulatus associated with cage farming in the gulf of eilat, red sea. | infection patterns of mycobacterium marinum were studied over a period of 3 yr in wild rabbitfish siganus nivulatus populations associated with commercial mariculture cages and inhabiting various sites along the israeli red sea coastline. mycobacteriosis was first recorded from the red sea in 1990 in farmed sea bass dicentrarchus labrax and is absent from records of studies on parasites and diseases of wild rabbitfish carried out in the 1970s and 1980s. a sharp increase in the prevalence of the ... | 2000 | 10768289 |
| granuloma-specific expression of mycobacterium virulence proteins from the glycine-rich pe-pgrs family. | pathogenic mycobacteria, including the agent of tuberculosis, mycobacterium tuberculosis, must replicate in macrophages for long-term persistence within their niche during chronic infection: organized collections of macrophages and lymphocytes called granulomas. we identified several genes preferentially expressed when mycobacterium marinum, the cause of fish and amphibian tuberculosis, resides in host granulomas and/or macrophages. two were homologs of m. tuberculosis pe/pe-pgrs genes, a family ... | 2000 | 10827956 |
| new clues to how the tb bacillus persists. | 2000 | 10847835 | |
| retrospective study of mycobacterium marinum skin infections. | although infection by mycobacterium marinum is well reported in the literature, there have been few epidemiologic studies. the purpose of this study was to review the epidemiology of patients with cutaneous m. marinum infection over a 3-year period at the national skin centre in singapore. | 2000 | 10849123 |
| [sporotrichoid infection with mycobacterium marinum: successful therapy with oral tetracycline administration]. | atypical mycobacterial infections of the skin present a diagnostic and therapeutic challenge to dermatologists in many instances. we report on a patient who was diagnosed with atypical mycobacteriosis in its rarer, sporotrichoid form. possible differential diagnoses are discussed. efficient therapy using minocycline is demonstrated. | 2000 | 10875074 |
| mycobacterium marinum hand infection: case reports and review of literature. | three patients with mycobacterium marinum infection are described. key elements in the diagnosis of this infection are a high index of suspicion, taking a history with an emphasis on exposure to tropical fish or other potential sources of m. marinum infection, and tissue biopsy for culture and histology. the microbiologist should be informed about the suspicion of m. marinum infection so that appropriate cultures can be performed. as m. marinum does not grow under routine culture conditions, the ... | 2000 | 10878841 |
| incubation period and sources of exposure for cutaneous mycobacterium marinum infection: case report and review of the literature. | the diagnosis of cutaneous mycobacterium marinum infection is often delayed for months after presentation, perhaps because important clinical clues in the patient's history are frequently overlooked. knowledge of the incubation period allows the clinician to target questions about the patient's history. prompted by a case with a prolonged incubation period, we sought to determine more precisely the incubation period of m. marinum infection. the medline database for the period 1966-1996 was searc ... | 2000 | 10987702 |
| [cutaneous nodular infection with hemopathy]. | a 36-year-old man with treated hairy cell leukemia developed a skin infection due to mycobacterium marinum. a spectrum of atypical cutaneous mycobacteriosis presentations with immunosuppression can be found. the recognition of the disease needs cutaneous biopsies for histopathology and its identification by specific laboratory methods to adapt treatment. | 2000 | 11015652 |
| antibiotic susceptibility pattern of mycobacterium marinum. | in vitro activities of 17 antibiotics against 53 clinical strains of mycobacterium marinum, an atypical mycobacterium responsible for cutaneous infections, were determined using the reference agar dilution method. rifampin and rifabutin were the most active drugs (mics at which 90% of the isolates tested were inhibited [mic(90)s], 0.5 and 0.6 microgram/ml, respectively). mics of minocycline (mic(90), 4 microgram/ml), doxycycline (mic(90), 16 microgram/ml), clarithromycin (mic(90), 4 microgram/ml ... | 2000 | 11036036 |
| applications of gene fusions to green fluorescent protein and flow cytometry to the study of bacterial gene expression in host cells. | 2000 | 11036634 | |
| skin disease and nontuberculous atypical mycobacteria. | 2000 | 11044189 | |
| comparative genetic analysis of mycobacterium ulcerans and mycobacterium marinum reveals evidence of recent divergence. | previous studies of the 16s rrna genes from mycobacterium ulcerans and mycobacterium marinum have suggested a very close genetic relationship between these species (99.6% identity). however, these organisms are phenotypically distinct and cause diseases with very different pathologies. to investigate this apparent paradox, we compared 3,306 nucleotides from the partial sequences of eight housekeeping and structural genes derived from 18 m. ulcerans strains and 22 m. marinum strains. this analysi ... | 2000 | 11053375 |
| a case report of mycobacterium marinum infection of the hand. | we report a case of mycobacterium marinum infection of the hand presenting initially as triggering of the digits. we like to highlight the unusual source of the infection and difficulty of diagnosis in this case as well as the various treatment modalities. | 2000 | 11063172 |
| [aquariums and mycobacterioses]. | mycobacterium infections are increasingly reported in fish fanciers who keep an aquarium. inoculation occurs on abraded skin after an incubation period of 2 to 3 weeks. clinically papulo-nodules, ulcers or verrucous plaques develop. these may progress into sporotrichoid lesions or into deeper infections involving tendons and bone. cultural identification is obtained by biopsy specimen at low temperature (30-33 degrees c). faster identification may be performed by polymerase chain reaction. histo ... | 2000 | 11068476 |
| susceptibility testing for mycobacteria. | mycobacterial susceptibility testing is important for the management of patients with tuberculosis and those with disease caused by certain nontuberculous mycobacteria. to help standardize methods used in the clinical microbiology laboratory for testing susceptibility of mycobacteria, the national committee for clinical laboratory standards (nccls) recently updated nccls document m24-t (published in 1995), which is the tentative standard for antimycobacterial susceptibility testing of mycobacter ... | 2000 | 11073754 |
| [rapidly growing mycobacteria in human pathology]. | 2000 | 11075485 | |
| variable numbers of ttc repeats in mycobacterium leprae dna from leprosy patients and use in strain differentiation. | strain differentiation of mycobacterium leprae would be of great value for epidemiological investigation to identify the infectious sources of leprosy, to understand transmission patterns, and to distinguish between relapse and reinfection. from the m. leprae genome sequence database, ttc dna repeats were identified. primer sets designed to amplify the region flanking ttc repeats revealed pcr products of different sizes, indicating that the number of repeats at each locus may be variable among m ... | 2000 | 11101592 |
| [chronic paronychia and synovialitis of extensor tendons due to mycobacterium marinum. is diagnosis or treatment the problem?]. | most infections of the upper extremity are caused by staphylococcus or streptococcus and respond well to beta-lactam antibiotics. hand surgeons should be aware of the possible diagnosis of mycobacterium marinum infection: 90% of the lesions are found in the upper extremity. we present a case of a chronic, cutaneous lesion of the right middle finger with synovialitis of the extensor tendons observed in a 35-year-old woman. routine cultures from tissue of the infected finger led to the diagnosis o ... | 2000 | 11103693 |
| cutaneous blastomycosis in new brunswick: case report. | blastomycosis is a fungal infection of immunocompetent hosts. we present a case of cutaneous blastomycosis acquired in new brunswick, which provides evidence that this disease is endemic in atlantic canada. this case also demonstrates that the diagnosis of blastomycosis may be elusive. perseverance, a high index of clinical suspicion and close cooperation with the microbiology laboratory may be required to diagnose this uncommon condition. | 2000 | 11107468 |
| topically acquired bacterial zoonoses from fish: a review. | the main pathogens acquired topically from fish (through spine puncture or open wounds) are aeromonas hydrophila, edwardsiella tarda, erysipelothrix rhusiopathiae, mycobacterium marinum, streptococcus iniae, vibrio vulnificus and vibrio damsela. s. iniae has recently emerged as a public health hazard associated with aquaculture, and m. marinum often infects home aquarium hobbyists. with the expansion of aquaculture and popularity of recreational fishing in australia, medical practitioners can ex ... | 2000 | 11130351 |
| [mycobacterium marinum nodular lymphangitis]. | mycobacterium marinum has been recognized for some forty years. it generally occurs after trauma in a patient who manipulates tropical fish living in an aquarium. | 2000 | 11147048 |
| picture of the month. mycobacterium marinum facial abscess. | 1999 | 10323638 | |
| health and safety concerns in fisheries and aquaculture. | only 10% of all foodborne illnesses in the united states are attributed to seafood, making seafood a relatively safe food commodity. the implementation of hazard analysis and critical control points guidelines should make seafood consumption even safer. concerns include closed-loop, indoor, water-recirculating production systems; harmful algal blooms in marine environments, which can cause paralytic, neurologic, amnesic, and diarrhetic shellfish poisonings and ciguatera fish poisoning; bacteria ... | 1999 | 10329911 |
| atypical mycobacterial cutaneous infection. | 1999 | 10330598 | |
| the mycobacterium marinum g13 promoter is a strong sigma 70-like promoter that is expressed in escherichia coli and mycobacteria species. | a mycobacterium marinum promoter, designated g13, was isolated from a promoter-trap library as a constitutive producer of the mutant green fluorescent protein. sequence analysis, primer extension analysis, and computer promoter prediction analysis indicate that the g13 promoter is very similar to escherichia coli consensus sigma 70 promoters. expression of the green fluorescent protein from the g13 promoter in m. marinum is, however, up to 40 times higher than that seen from the mycobacterial hs ... | 1999 | 10361711 |
| mycobacterium marinum with associated bursitis. | mycobacterium marinum infections have been reported for over 50 years, mostly in association with trauma in the setting of water exposure. | 1999 | 10366400 |
| superoxide production in phagocytes obtained from mycobacterium marinum-stimulated goldfish (carassius auratus) that were exposed to copper. | to investigate the effects of copper exposure and recovery from copper toxicosis on the nonspecific immune response in mycobacterium marinum-inoculated goldfish. | 1999 | 10376889 |