Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| in vitro study of the antibacterial activity of ofloxacin against recent clinical isolates. | the in vitro activity of ofloxacin, a new broad-spectrum antimicrobial agent, was studied by a standardized single disc method. a total of 990 clinical isolates were tested, including 20 strains of anaerobic bacteria. ofloxacin was highly active against 683 strains (70.41%), had intermediate activity against 109 (11.23%) and had no activity against 178 (18.35%). ofloxacin was highly active against e. coli, klebsiella sp., citrobacter sp., proteus mirabilis, proteus morganii, salmonella sp., camp ... | 1987 | 3476290 |
| efficacy and tolerance of oral ofloxacin in treating various infections. | 66 patients were given daily doses of ofloxacin between 400 and 800 mg for 10 days to 6 months. they were suffering from exacerbation of chronic bronchitis (15), soft tissue phlegmon (11), complicated urinary tract infections (7), bronchopneumonia (7), chronic osteomyelitis in exacerbation (8), chronic prostatitis in exacerbation (5), lower urinary tract infections (3), chronic otitis media (3), acute otitis (3), acute bronchitis (1), lung abscess (2) or liver abscess (1). pathogens included pse ... | 1987 | 3481312 |
| inducible expression of an aminoglycoside-acetylating enzyme in providencia stuartii. | strains of providencia stuartii were collected from a chronic-care geriatric ward of a large veteran's administration hospital. two strains of p. stuartii, and one of escherichia coli isolated from the same ward, were transferred five times in the presence of gentamicin or netilmicin. at the fifth transfer the mics of both gentamicin and netilmicin for the two p. stuartii strains had increased at least ten-fold. the mics for the e. coli remained essentially unchanged. enzyme assay demonstrated i ... | 1987 | 3549668 |
| diversity of the phosphoenolpyruvate/glucose phosphotransferase system in the enterobacteriaceae. | the presence of the phosphoenolpyruvate glucose phosphotransferase entry routes was studied in 97 genospecies of enterobacteriaceae. phosphoenolpyruvate(pep)-dependent phosphorylation of alpha-methyl-d-glucoside and 2-deoxyglucose was evidenced in 72 species (group i organisms), suggesting the presence of both the iiglc (formerly ii-bglc/iiiglc) and iiman (formerly ii-b/ii-aman) entry routes. erwinia amylovora, budvicia aquatica and all species of leminorella and proteus (as defined by dna relat ... | 1987 | 3606872 |
| genetic and biochemical diversity of ureases of proteus, providencia, and morganella species isolated from urinary tract infection. | bacterial urease, particularly from proteus mirabilis, has been implicated as a contributing factor in the formation of urinary and kidney stones, obstruction of urinary catheters, and pyelonephritis. weekly urine specimens (n = 1,135) from 32 patients, residing at two chronic-care facilities, with urinary catheters in place for greater than or equal to 30 days yielded 5,088 phenotypically and serotypically diverse bacterial isolates at greater than or equal to 10(5) cfu/ml. a total of 86% of sp ... | 1987 | 3623698 |
| gram-negative septicemia caused by providencia stuartii. | the role of urologic disease and manipulation of the genito-urinary tract in the pathogenesis of gram-negative bacteremia has been long recognized. among these organisms, species of providencia genus have been increasingly reported. we describe a 17-year-old male paraplegic who developed septic shock due to providencia stuartii following urinary tract manipulation and responding to medical therapy. this is unusual as most cases with septic shock from providencia species will succumb. it is impor ... | 1987 | 3654064 |
| fractionation of the providencia stuartii cell envelope. | cell envelopes (i.e. unfractionated inner and outer membranes) were obtained from providencia stuartii by following procedures previously applied to the isolation of envelopes from escherichia coli. the p. stuartii envelopes contained known inner membrane enzymes that included a variety of dehydrogenases and atpase. the catalytic activity of the atpase depended upon the concentration of magnesium ions, the substrate (atp) level and the ratio of magnesium ions to atp. cell envelopes from p. stuar ... | 1987 | 3668499 |
| properties of equine anti-lipopolysaccharide hyperimmune plasma: binding to lipopolysaccharide and bactericidal activity against gram-negative bacteria. | anti-lipopolysaccharide equine hyperimmune plasma (anti-lps), which has been used successfully to treat lps (endotoxin)-mediated disorders, has been further characterised. igg present in anti-lps had the highest affinity for lps prepared from salmonella typhimurium, s. typhi, s. abortus equi and shigella flexneri and intermediate affinity for escherichia coli o55:b5, e. coli o127:b8 and s. enteritidis. anti-lps destroyed by means of complement activation a wide range of gram-negative bacteria, i ... | 1987 | 3669052 |
| [isolation and properties of aminocaprolactam hydrolase from providencia alcalifaciens]. | l-alpha-aminocaprolactam hydrolase possessing the l-lysinamidase activity was isolated and purified from providencia alcalifaciens. the purification procedure of enzymes included cell destruction on usdl-1, fractionation by ammonium sulfate, gel-chromatography on g-100, ion exchange chromatography on deae-cellulose. the purification resulted in a homogeneous enzyme which possessed the both activities. the enzyme molecular weight (180 kda) was estimated by gel chromatography on sephadex g-200. km ... | 1987 | 3810885 |
| rapid catalase supplemental test for identification of members of the family enterobacteriaceae. | a simple, rapid, semiquantitative slide catalase test useful for differentiating members of the family enterobacteriaceae is described. judging by the time required for appearance of oxygen bubbles in 3% hydrogen peroxide, the immediate catalase reactors were yersinia, serratia, proteus, morganella, providencia, cedecea, and hafnia spp. the delayed catalase reactors were escherichia, shigella, klebsiella, enterobacter, salmonella, citrobacter, edwardsiella, kluyvera, and tatumella spp. this info ... | 1987 | 3818934 |
| uropathogenicity in rats and mice of providencia stuartii from long-term catheterized patients. | providencia stuartii, a frequent and persistent isolate from the urinary tract of chronically catheterized elderly patients, is multiply antibiotic resistant and may cause fatal bacteremia in those patients. we studied p. stuartii strains in rats and mice to determine differences in uropathogenicity. strains studied varied in expression of factors which contribute to pathogenicity of other bacterial species. urinary tract responses following challenge with p. stuartii strain ho (factors expresse ... | 1987 | 3625871 |
| [high mortality of the nile tilapia oreochromis niloticus caused by providencia rettgeri]. | 1987 | 3632601 | |
| identification of porins in outer membrane of proteus, morganella, and providencia spp. and their role in outer membrane permeation of beta-lactams. | proteus mirabilis, proteus vulgaris, morganella morganii, providencia rettgeri, and providencia alcalifaciens, which were once classified into the same genus, proteus, were studied. cefoxitin-resistant mutants from these species were isolated, and it was confirmed that the resistance was attributed to the lack of an outer membrane protein, resulting in a significant decrease in the penetration of hydrophilic cephalosporins through the outer membrane. comparison of the mutant strains with their p ... | 1987 | 3034144 |
| preliminary studies on the effect of glutathione s-transferase from providencia stuartii on the antimicrobial activity of different antibiotics. | glutathione s-transferase has been isolated and purified from a providencia stuartii ch 114 strain. the effect of the enzyme on the antimicrobial activity of amikacin, cefotaxime, cephalexin, ampicillin, nalidixic acid, and ofloxacin was tested. the efficiency of all antibiotics tested, except nalidixic acid and ofloxacin, is relevantly decreased by the presence of glutathione s-transferase in the medium culture, as proved by the increased value of mic. the effect of glutathione s-transferase on ... | 1987 | 3427694 |
| urease activity of proteus penneri. | ten strains of proteus penneri isolated from geographically diverse laboratories were tested for urease activity. cell lysates from urea-induced cells had a mean activity of 4.9 +/- 4.1 mumol of nh3 per min per mg of protein. on nondenaturing 6% polyacrylamide activity gels, the enzymes of p. penneri had very similar electrophoretic mobilities within species and within the proteus genus but were distinct from the ureases of providencia and morganella species. on lower-percentage polyacrylamide, ... | 1987 | 3429622 |
| comparative in vitro activities of 13 antimicrobial agents against morganella-proteus-providencia group bacteria from urinary tract infections. | we examined 741 urinary tract isolates of the morganella-proteus-providencia group, including the recently defined species proteus penneri, for susceptibilities to aminoglycosides, semisynthetic penicillins, and cephalosporins. the data emphasize the importance of identification to the species level on the basis of marked species differences in patterns of susceptibility. | 1987 | 3435110 |
| numerical analysis of electrophoretic protein patterns of providencia rustigianii strains from human diarrhoea and other sources. | twenty strains of providencia rustigianii (including the type strain of prov. friedericiana) have been characterized by one-dimensional sds-page of cellular proteins. they comprised 12 strains (almost exclusively associated with the intestinal tract) from humans, plus eight largely from the intestinal tract of pig, penguin and environmental sources. the protein patterns, which contained 45-50 discrete bands, were highly reproducible and were used as the basis for two numerical analyses. in the f ... | 1987 | 3436856 |
| nosocomial infectious balanoposthitis in neutropenic patients. | we have reported balanoposthitis as a source of fever and bacteremia in two neutropenic uncircumcised patients. the etiologic organisms were pseudomonas aeruginosa in one case and providencia stuartii in the other. in one patient, the diagnosis was delayed by the presence of a condom catheter. this emphasizes the importance of personal hygiene in uncircumcised men about to undergo immunosuppressive therapy, and the need for judicious use of condom catheters in such patients. | 1987 | 3110971 |
| [study of the sensitivity to pipemidic acid, pefloxacin and norfloxacin of 444 bacterial strains isolated at a general hospital]. | after one year of use of pefloxacin in the intensive care unit, medicine unit and surgery unit and the following recent commercialization without prescription of norfloxacin, we studied for a period of two months (april and may 1986) the susceptibility to pipemidic acid, to pefloxacin and norfloxacin of 444 bacteria strains isolated obtained from clinical specimens. the antibiotic susceptibility is determined by disk diffusion test. we obtained the following results: susceptible methicillin stap ... | 1987 | 3112705 |
| disk diffusion susceptibility testing and broth microdilution quality control guidelines for bmy-28100, a new orally administered cephalosporin. | the bmy-28100 30-micrograms-disk test was evaluated by using 615 clinical isolates. regression analyses and error rates were determined, leading to the recommendation of greater than or equal to 18-mm zone diameters (mic correlate, greater than or equal to 8.0 micrograms/ml) for susceptibility and less than or equal to 14-mm zone diameters (mic correlate, greater than or equal to 32 micrograms/ml) for resistance. nearly all false-susceptible disk test results were among the providencia spp. and ... | 1987 | 3121667 |
| assessment of antiseptic bladder washout procedures using a physical model of the catheterised bladder. | a simple physical model of the catheterised bladder has been used to assess the activities of antiseptic agents that have been recommended as bladder instillations in the treatment of urinary tract infections in patients with indwelling catheters. the activities of povidone-iodine, phenoxyethanol, chlorhexidine, chlorhexidine supplemented with edta + tris, noxythiolin and neomycin were examined against selected species of uropathogens. except for phenoxyethanol against pv. stuartii and possibly ... | 1987 | 3122868 |
| comparative antibacterial activity of a new oral cephalosporin, bmy-28100. | bmy-28100 is a new oral cephalosporin which had in vitro activity superior to that of cephalexin and cefaclor against staphylococci, beta-hemolytic streptococcal species, and streptococcus pneumoniae. it inhibited beta-lactamase-producing haemophilus influenzae, neisseria gonorrhoeae, 50% of streptococcus faecalis isolates, listeria monocytogenes, and 50 to 75% of escherichia coli and klebsiella species at less than or equal to 8 micrograms/ml, but high producers of beta-lactamase were resistant ... | 1987 | 3495236 |
| in vitro activity and beta-lactamase stability of a new penem, cgp 31608. | the in vitro activity of cgp 31608, a new penem, against aerobic and anaerobic organisms was evaluated and compared with those of other beta-lactams. cgp 31608 inhibited escherichia coli, klebsiella pneumoniae, k. oxytoca, proteus mirabilis, citrobacter diversus, and salmonella, shigella, aeromonas, and yersinia spp. with mics for 50% of the strains (mic50s) of 2 to 4 micrograms/ml and mic90s of 4 micrograms/ml, compared with cefotaxime, ceftazidime, aztreonam, and imipenem mics of less than 0.2 ... | 1987 | 3496845 |
| in vitro activity of cefixime and six other agents against nosocomial pathogens of the enterobacteriaceae family. | cefixime, a broad-spectrum, orally active cephalosporin, was more active in vitro than ampicillin, cefaclor, cephalothin, and trimethoprim/sulfamethoxazole against 194 nosocomial pathogens of the family enterobacteriaceae. activity was especially good against klebsiella spp, proteus spp, serratia spp, and providencia stuartii. although gentamicin had equivalent or better activity against citrobacter spp, enterobacter spp, escherichia coli, and morganella morganii, all 23 of the gentamicin-resist ... | 1987 | 3498702 |
| [in vitro comparison of the beta lactamase-inhibitory action of clavulanic acid and sulbactam in ampicillin-resistant enterobacteria]. | comparative in vitro studies of the beta-lactamase inhibitory effects of clavulanic acid and sulbactam on ampicillin-resistant enterobacteria. clavulanic acid and sulbactam alone are infective against pseudomonas and enterococci. staphylococci and enterobacteriaceae are inhibited by high concentrations not attainable under clinical conditions. strains of acinetobacter, especially a. lwoffii are susceptible to clavulanic acid and highly susceptible to sulbactam. the sulbactam-ampicillin combinati ... | 1987 | 3501722 |
| dna probe technology for detection of haemophilus influenzae. | a 5 kb haemophilus influenzae dna fragment involved in penicillin-binding proteins expression was used as a probe for specific detection of h. influenzae strains. the 32p-labeled probe specificity was assessed by hybridization to bacterial dots and 75 strains were tested. all h. influenzae (18) and h. aegyptius (1) strains reacted very strongly with the probe. the h. influenzae serotypes tested (a, b, and non-typable strains) did not differ in their hybridization. some hybridization was also fou ... | 1987 | 3502611 |
| in vitro activity and beta-lactamase stability of a new monobactam, b0-1165. | b0-1165 is a 1-carboxy-1-cyclopropoxyamino,4-fluoromethyl monobactam. it inhibited the majority of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, citrobacter diversus, aeromonas hydrophila, proteus mirabilis, proteus vulgaris, providencia rettgeri, providencia stuartii, yersinia enterocolitica, haemophilus influenzae, neisseria gonorrhoeae, and salmonella and shigella species at less than or equal to 0.125 microgram/ml. overall, its in vitro activity was similar to that of aztreona ... | 1987 | 3300528 |
| [antibacterial activity of enoxacin in vitro and in urine]. | minimal inhibitory concentrations (mic) of enoxacin (eno) were evaluated by agar dilution, in comparison with mic of nalidixic acid (nal), pipemidic acid (pip), oxolinic acid (oxo), pefloxacin (pef), norfloxacin (nor), ofloxacin (ofl) and ciprofloxacin (cip), for eleven enterobacteriaceae reference strains chosen as a function of sensitivity and level of resistance to nal. in the four strains susceptible to nal, mic of eno (0.06 to 0.25 micrograms/ml) were similar to those for pef and nor, 2 to ... | 1987 | 3302849 |
| in vitro and in vivo antibacterial activities of cs-807, a new oral cephalosporin. | cs-807 is a new oral prodrug of r-3746, a cephalosporin derivative, with potent in vitro and in vivo antibacterial activity against both gram-positive and gram-negative bacteria. the susceptibility of about 1,200 clinical isolates to r-3746 was determined by the agar dilution method. ninety percent or more of pathogens such as staphylococcus aureus, streptococci, escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, indole-positive and indole-negative proteus spp., providencia rettgeri, a ... | 1987 | 3310868 |
| ceforanide. a review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. | ceforanide is a 'second generation' cephalosporin administered intravenously or intramuscularly. it is similar to cefamandole and cefonicid in its in vitro superiority to 'first generation' cephalosporins against several species of enterobacteriaceae as well as its activity against haemophilus influenzae, including beta-lactamase-producing strains. its activity against staphylococcus aureus is less than that of cefamandole, cefuroxime and first generation cephalosporins. the in vitro activity ag ... | 1987 | 3315624 |
| [drug resistance of proteus vulgaris, proteus morganii and providencia rettgeri isolated from diagnostic specimens]. | 1987 | 3324173 | |
| microbiological perspectives of co-trimoxazole. | trimethoprim-sulfamethoxazole in vitro activity was compared with ampicillin, tetracycline, sulfonamide and trimethoprim against isolates of 24 gram-negative and 11 gram-positive species. the incidence of more than 10% of strains with minimal inhibitory concentrations above 32 mg/l was restricted to escherichia coli, shigella spp., klebsiella pneumoniae, providencia rettgeri, morganella morganii, methicillin-resistant staphylococcus aureus and staphylococcus epidermidis. occasionally, streptococ ... | 1987 | 3325434 |
| [the antimicrobial activity of sisomicin against fresh clinical isolates]. | antimicrobial activities of sisomicin (siso) against clinical isolates obtained in the second half of 1986 were investigated together with other 4 aminoglycosides (ags) (gentamicin (gm), tobramycin (tob), dibekacin (dkb), amikacin (amk] and 2 cephems (cefotiam, cefotaxime), and were compared to the results reported in the period of late 1970's through early 1980's in japan. 1. the incidence of siso-resistant staphylococcus aureus in the present study was 18% and is comparable to that of the othe ... | 1987 | 3327965 |
| investigation of a providencia rettgeri strain that has enterobacterial common antigen in the immunogenic state. | antigenic material obtained by phenol-water extraction from providencia rettgeri strains, escherichia coli o:14 strains, and mutants of the e. coli o:14 strain were examined by the passive (indirect) hemagglutination technique, by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and by immune blotting (lipopolysaccharide (lps) blotting). providencia rettgeri 965, like e. coli o:14, was demonstrated to have an enterobacterial common antigen (eca) in the immunogenic form but, unlike e. c ... | 1987 | 3328641 |
| the organization and control of expression of the pst i restriction-modification system. | 1987 | 3333366 | |
| inhibition of providencia stuartii cell envelope enzymes by chlorhexidine. | the possibility that chlorhexidine is a specific inhibitor of membrane bound bacterial adenosine triphosphatase (atpase) was addressed. the in-vitro susceptibilities of several providencia stuartii cell envelope enzymes, including atpase, to chlorhexidine were compared. the following concentrations of chlorhexidine were required to cause 50% inhibition of enzyme activity in preparations from chlorhexidine-sensitive strains (mic 50 mg chlorhexidine/l): atpase (160 mg/l), succinic dehydrogenase (g ... | 1987 | 2956230 |
| survey of multiply resistant providencia stuartii in a chronic care unit. | providencia stuartii was cultured over a 4-year period from the urinary tract, throat, perineum, axilla and stools of patients in a long-term chronic care unit, the most common site of colonization being the urinary tract. a total of 17 patients had prov. stuartii bacteraemia and manipulation of the urinary tract preceded bacteraemia in 10 cases. eighty-two per cent of the patients had long-term urinary tract colonization from 1 month to 4 years. although most isolates were resistant to all amin ... | 1987 | 2883227 |
| the resistance of urinary tract pathogens to chlorhexidine bladder washouts. | isolates of providencia stuartii, pseudomonas aeruginosa, proteus mirabilis, klebsiella pneumoniae and streptococcus faecalis from urinary-tract infections in spinally-injured patients together with escherichia coli 10418 were challenged with chlorhexidine (200 mg l-1) in a model of a catheterized bladder under conditions which simulate the bladder washout technique. all species survived the antiseptic. organisms growing on the wall of the bladder model appeared to be particularly resistant and ... | 1987 | 2888808 |
| modifications of dna-gyrase and of permeability in a norfloxacin-resistant clinical isolate of providencia stuartii. | we obtained a clinical isolate of providencia stuartii showing a high level of resistance to norfloxacin and to other 4-quinolones, whose target is the enzyme dna-gyrase. this strain showed resistance also to beta-lactam and aminoglycoside antibiotics. in order to detect modification of dna-gyrase, we performed supercoiling assays in vitro in presence of norfloxacin and ciprofloxacin. furthermore, outer membrane proteins, which are involved in permeability mechanisms, were analyzed on sds-polyac ... | 1987 | 2826973 |
| [antibacterial activity of a number of preparations and their combination with a proteolytic enzyme against the microflora of burn and surgical wounds]. | antibacterial activity of antibiotics (azlocillin, tobramycin and piperacillin), antiseptics (metacid, chlorhexidine and quinosoline) and some other drugs (dioxidine and mafenide acetate) against the main representatives of the burn and surgical wound microflora, i. e. staphylococcus, p. aeruginosa, proteus, providencia, serratia, klebsiella and e. coli was studied. tobramycin and piperacillin were highly active against p. aeruginosa, staphylococcus and proteus. it was shown that in the presence ... | 1986 | 2425729 |
| providencia stuartii: a common cause of antibiotic-resistant bacteriuria in patients with long-term indwelling catheters. | the long-term-catheterized urinary tract may offer a particular niche to providencia stuartii, which is otherwise an uncommon clinical isolate. published accounts of bacteriuria in patients catheterized for long periods indicate that p. stuartii has often been found as frequently as familiar uropathogens such as escherichia coli, proteus mirabilis, enterococcus, and pseudomonas aeruginosa. as in most nosocomial infections, the frequency of isolation of a given species has commonly differed among ... | 1986 | 3081988 |
| distribution of bacteria and yeasts within the 10-ml isolator during the processing of seeded blood samples. | forty-five organisms consisting of stock cultures and clinical isolates of bacteria and yeast were separately inoculated into outdated blood bank blood to achieve a concentration of approximately 100 cfu/ml. blood with each organism was introduced into groups of four isolators (e. i. du pont de nemours & co., inc., wilmington, del.), which were then processed according to the isostat instructions of the manufacturer. the supernatant, sediment, and wash (material removed from the surface of the s ... | 1986 | 3084546 |
| [antibacterial activity of (+)-negamycin prepared by a new method]. | antibacterial activity of (+)-negamycin (ngm) prepared by a new method was investigated for some bacteria. the results demonstrated that this antibacterial activity of synthesized ngm was almost the same as compared to that of naturally obtained ngm, and was also effective to pseudomonas aeruginosa harboring multiple drug resistant plasmid kr102. | 1986 | 3084829 |
| in vitro evaluation of a-56619 (difloxacin) and a-56620: new aryl-fluoroquinolones. | the in vitro antibacterial potencies of a-56619 and a-56620, two new aryl-fluoroquinolones, were compared with the potency of norfloxacin against a broad spectrum of organisms. cefotaxime, aztreonam, piperacillin, imipenem, penicillin, and gentamicin were also tested for reference purposes. the mics required to inhibit at least 90% of the strains tested ranged from 0.25 to 4 micrograms/ml for a-56619 and from 0.06 to 0.5 microgram/ml for a-56620 for members of the enterobacteriaceae. a-56619 was ... | 1986 | 3087274 |
| survey of aminoglycoside resistance patterns. | we studied the susceptibility of 545 gram-negative clinical isolates to six aminoglycosides: gentamicin, tobramycin, netilmicin, amikacin, 2'-n-ethylnetilmicin, and 6'-n-ethylnetilmicin. the resistant strains (359) have been classified into aminoglycoside resistance (patterns) phenotypes (agrps) corresponding to known resistance mechanisms. the results clearly demonstrated that most strains of proteus spp., klebsiella spp., escherichia coli and pseudomonas aeruginosa appeared to be able to adeny ... | 1986 | 3087636 |
| resistance of providencia stuartii to chlorhexidine: a consideration of the role of the inner membrane. | spheroplasts of three strains of providencia stuartii (one sensitive, one moderately sensitive and one resistant to chlorhexidine) were induced by cefoxitin, glycine or a lysozyme-tris-edta combination, and their susceptibility to chlorhexidine-induced lysis investigated. maximum lysis of spheroplasts occurred at a low (2.5-5 micrograms/ml) concentration of chlorhexidine and was greatest with the most sensitive strain, pv2. the possible role of the inner membrane in chlorhexidine resistance is c ... | 1986 | 3087933 |
| in vitro activity of aztreonam against gram negative bacteria from clinical specimens and its comparison with other commonly used antibiotics. | a total of 755 gram negative bacteria isolated from clinical specimens were tested against aztreonam by the disc agar diffusion test. the strains of bacteria used in this study consisted of escherichia coli (314), enterobacter aerogenes (30), e. agglomerans (7), e. cloacae, (39), citrobacter diversus (9), c. freundii (13), hafnia alvei (3), acinetobacter calcoaceticus (10), klebsiella oxytoca (6), k. ozaenae (5), k. pneumoniae (107), morganella morganii (3), moraxella sp. (10), pasteurella multo ... | 1986 | 3088346 |
| aminoglycosides plus beta-lactams against gram-negative organisms. evaluation of in vitro synergy and chemical interactions. | combination antibiotic therapy has been used mainly to broaden the antibacterial spectrum and prevent the development of resistance. antibiotic combinations proven to be synergistic in vitro are associated with a significantly better in vivo response, particularly in the compromised host in whom traditional treatment combines an antipseudomonal penicillin plus an aminoglycoside. several investigators have examined combining new agents, such as the third-generation cephalosporins (cefotaxime, cef ... | 1986 | 3088998 |
| review of epidemic aminoglycoside resistance worldwide. | epidemic aminoglycoside resistance may be caused by the spread of a species with distinctive chromosomal genes (e.g., pseudomonas aeruginosa), or it may be due to the dissemination of plasmids or transposons between genera. although strains of p. aeruginosa resistant to aminoglycosides because of impermeability may cause nosocomial outbreaks, most of the acute increases in aminoglycoside resistance are due to the spread of inactivating enzymes by plasmids. the index species for intergeneric outb ... | 1986 | 3089005 |
| comparison of bacteria in the tympanic cavity and the mastoid antrum in chronic otitis media. | materials collected from the tympanic cavity before operation and from the mastoid antrum during operation of 58 discharging ears of patients with chronic otitis media were cultured, and the bacteria in these two cavities were compared. staphylococcus aureus was the commonest organism in the tympanic cavity, and s epidermidis in the mastoid antrum. anaerobic bacteria were found only in the mastoid antrum of patient with cholesteatoma. in 32 (55 per cent) of the 58 ears examined, bacteria were de ... | 1986 | 3092687 |
| do clinical microbiology laboratories report complete bacteriology in urine from patients with long-term urinary catheters? | bacteriuria associated with long-term urinary catheters (those in place for greater than or equal to 30 days) appears to be the most common nosocomial infection in u.s. medical care facilities. this bacteriuria is polymicrobial and dynamic and accompanied by fevers, catheter obstructions, bacteremias, and deaths. we compared the reporting by our research laboratory of bacteria present in urine from long-term-catheterized nursing home patients with that by two commercial laboratories. the commerc ... | 1986 | 3093528 |
| [in-vitro activity of cefonicid on hospital bacteria. regression line and proposal for critical values]. | antimicrobial activity of cefonicid, a new second generation cephalosporin, against 315 hospital isolates (4th trimester 1984) was investigated. e. coli and proteus mirabilis were the most susceptible species. all e. coli strains except one were inhibited at 8 mg/l (modal mic: 0.5); mics of all indole + proteus were 8 mg/l (modal mic: 0.06). another group was moderately susceptible: mics of klebsiella and citrobacter ranged from 0.12 to 128 mg/l, but mics of 50% of these strains were less than o ... | 1986 | 3095773 |
| [a clinical bacteriological efficacy study on a fosfomycin otic solution]. | fosfomycin (fom) otic solution was administered to 587 patients with suppurative otitis media infections including 190 patients in the dose-establishment test, 126 patients in the open clinical trial and 271 patients in the double blind test. various bacteria were detected in the 549 cases in which bacteriological investigation was possible. main bacteria detected from the above cases were s. aureus (261 strains, 47.5%), p. aeruginosa (93 strains, 16.9%), coagulase negative staphylococci (cns) ( ... | 1986 | 3099028 |
| reversal of the surface effects of chlorhexidine diacetate on cells of providencia stuartii. | chlorhexidine diacetate (cha) increased the hydrophobicity of the cell surface of cells of three strains of providencia stuartii. removal of at least some of the cha from the cells by washing them with an appropriate antidote partially reversed the hydrophobicity-increasing action of the biguanide. the effects of other treatments on cell surface hydrophobicity were examined with these strains and, for comparison, with two strains each of escherichia coli and pseudomonas aeruginosa: ethylenediami ... | 1986 | 3100485 |
| antibacterial properties of imipenem with special reference to the activity against methicillin-resistant staphylococci, cefotaxime-resistant enterobacteriaceae and pseudomonas aeruginosa. | imipenem was examined with standardized agar dilution procedures against a wide range of bacteria. geometric mean mics against the genera escherichia, klebsiella, enterobacter, citrobacter and serratia were 0.1-0.4 mg/l, and proteus and providencia spp. were inhibited by 0.25-4 mg/l. acinetobacter calcoaceticus var. anitratum strains were inhibited by concentrations ranging from 0.12-0.5 mg/l. methicillin-susceptible staphylococci were highly susceptible to the drug (mics: less than or equal to ... | 1986 | 3102452 |
| rare occurrence of proteus vulgaris in faeces: a reason for its rare association with urinary tract infections. | the faecal carriage rates of different species of proteeae were assessed in studies with 220 faecal isolates from 219 individuals of whom approximately one-third were well and the remainder had gastro-enteritis. as a result of the development of new media that allowed replacement of the phenylalanine deaminase test with the tryptophan deaminase test and made it possible to combine tests for indole and urease production and for hydrogen sulphide and ornithine decarboxylase formation in two single ... | 1986 | 3512839 |
| occurrence and pathogenic role of morganella-proteus-providencia group bacteria in human feces. | a total of 2,693 fecal specimens, with 1,422 from healthy persons and 1,271 from patients suffering from enteric diseases, was investigated to isolate species of the morganella-proteus-providencia group and to evaluate the role of these bacteria in intestinal disorders. most strains were isolated from two media, i.e., blood agar and tryptophan agar. two of the species were more frequently found in diarrheal cases than in healthy controls. these species were morganella morganii and proteus mirabi ... | 1986 | 3517057 |
| effect of inoculum size on ampicillin and amoxycillin susceptibility determined by gas-liquid chromatography for members of the family enterobacteriaceae. | inoculum size had only a small effect on the results for ampicillin and amoxycillin susceptibility testing of escherichia coli. in contrast, a difference in inoculum size from 10(6) to 10(8) cfu/ml profoundly affected the results for ampicillin and amoxycillin susceptibility testing of proteus mirabilis, causing a change from susceptibility to complete resistance. these different effects of inoculum size were observed both when susceptibility was determined by the suppression of a characteristic ... | 1986 | 3517063 |
| lipopolysaccharide of providencia rettgeri. chemical studies and taxonomical implications. | the chemical constitutional analysis of the lipopolysaccharide (lps) isolated from providencia rettgeri was carried out. polyacrylamide gel electrophoresis using sodium dodecylsulfate or sodium deoxycholate showed that the lipopolysaccharide mostly consisted of short sugar chains. the lipid a was precipitated out after mild acid hydrolysis of lps. from the supernatant degraded polysaccharide and unsubstituted core fractions were isolated. compositional analysis of the core material revealed the ... | 1986 | 3524498 |
| ferric ammonium citrate decomposition--a taxonomic tool for gram-negative bacteria. | the iron uptake test of szabó and vandra has been modified and used for the differentiation of gram-negative bacteria. nutrient agar containing 20 g per litre of ferric ammonium citrate was distributed into narrow tubes and solidified so as to form butts and slants. considering the localization of the rusty-brown coloration produced after seeding and incubation, 2367 strains were classified into four groups. (1) unchanged medium: escherichia coli, shigella spp., yersinia spp., hafnia alvei and m ... | 1986 | 3529797 |
| [multicenter study of ofloxacin activity on bacteria isolated from a hospital environment]. | minimal inhibitory concentrations (mics) of ofloxacin were evaluated by agar dilution for 1508 bacterial strains isolated in five hospitals. for enterobacteriaceae sensitive to nalidixic acid, mics ranged from 0.008 to 1 microgram/ml (mode mic: 0.12); the different species of enterobacteriaceae exhibited similar mode mics (0.12) with the exception of e. coli (0.06-0.12), p. mirabilis (0.5) and providencia (0.25). among strains intermediate and resistant to nalidixic acid, most of which were serr ... | 1986 | 3534711 |
| [clinical evaluation of timentin in intensive care]. | 16 patients admitted to a micu were treated with timentin (ticarcillin + clavulanic acid) for bacterial infections: 11 cases of pulmonary infection, 3 cases of urinary tract infection, 2 septic shocks, 3 septicemias and 1 case of multifocal infection. the pathogens considered as a firmly established cause of infection were: 5 acinetobacter, 12 pseudomonas, 3 serratia, 4 klebsiella, 1 e. coli, 2 proteus, 1 providencia, 1 staphylococcus aureus, 1 staphylococcus epidermidis, 1 streptococcus d and 1 ... | 1986 | 3534719 |
| [urinary tract infections in general medical practice. a study of clinical findings, of the distribution of causative microbial species and their sensitivity to 16 antibiotics]. | from april to july 1984, all of the strains recovered by 10 private laboratories in upper-normandy region (france) from urine samples from outpatients seen in office practices (public and private hospitals excluded) were preserved. a total of 829 strains were collected, identified and tested against antibiotics using disk diffusion techniques. these investigations, together with a synthesis of clinical findings, were carried out by the laboratory of bacteriology of the rouen university hospital. ... | 1986 | 3534727 |
| [in vitro activity of carumonam (ro 17-2301) on hospital bacteria]. | minimal inhibitory concentrations (mics) of carumonam (ro 17-2301), a new synthetic antibacterial agent of the monobactam group, were evaluated by agar dilution for 399 hospital isolates. ro 17-2301 was inactive against gram positive and anaerobic bacteria. most enterobacteriaceae were inhibited by concentrations less than 1 microgram/ml, with mode mics approximating 0.03 micrograms/ml except for providencia (0.016), citrobacter (0.06), serratia (0.06) and enterobacter (0.12). a few strains, mos ... | 1986 | 3534745 |
| prevalence of colonization with antibiotic resistant gram-negative bacilli in a nursing home care unit: the importance of cross-colonization as documented by plasmid analysis. | a prevalence study was carried out on a 100-bed veterans administration nursing home care unit to determine the extent of colonization with gentamicin-resistant gram-negative bacilli (grgnb). hand cultures of 12 employees and 17 environmental cultures were negative. twenty-six of 86 (30%) patients were colonized with 49 grgnb. sixteen patients (19%) had urinary colonization. multivariate analysis revealed significant associations between rectal or perineal colonization (p less than 0.01), and th ... | 1986 | 3536783 |
| two-dimensional thin-layer chromatography for simultaneous detection of bacterial beta-lactam acylases and beta-lactamases. | a rapid and specific procedure was developed for the simultaneous detection of bacterial acylases and beta-lactamases, using ampicillin and cephalexin as substrates. bacterial suspensions from agar plates were incubated separately with each beta-lactam substrate for 1 h at 37 degrees c. the supernatant of the reaction mixture was dansylated, and the dansyl derivatives were separated by two-dimensional thin-layer chromatography on polyamide sheets. the end products resulting from acylase hydrolys ... | 1986 | 3539008 |
| speciation, serotyping, antimicrobial sensitivity and plasmid content of proteeae from the environment of calf-rearing units in south west england. | a survey was undertaken of the occurrence, serotype, antimicrobial sensitivity and plasmid content of members of the tribe proteeae in the environment of two calf-rearing units in the county of avon in south west england. examples of the following species were found: proteus mirabilis, prot. vulgaris, prot. vulgaris biogroup 2, morganella morganii, providencia stuartii, prov. alcalifaciens and prov. rettgeri. a wide range of serotypes was found, many having been previously reported from nosocomi ... | 1986 | 3540110 |
| ciprofloxacin therapy in complicated urinary tract infections caused by pseudomonas aeruginosa and other resistant bacteria. | thirty courses of ciprofloxacin were given to 28 patients with complicated urinary tract infections mainly caused by pseudomonas aeruginosa. all patients had severe underlying abnormalities and infection usually followed urethral catheterization. the infecting organisms were eradicated from the urine of all patients during therapy and 89% were still clear five to nine days after treatment. at one month follow up the cure rate had fallen to 64%. an increase in resistance to ciprofloxacin was seen ... | 1986 | 3542943 |
| comparative activities of the beta-lactamase inhibitors ytr 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant enterobacteriaceae and pseudomonads. | the in-vitro synergistic activity of ytr 830, a new beta-lactamase inhibitor, combined with four extended-spectrum penicillins (ticarcillin, piperacillin, mezlocillin and apalcillin) against ticarcillin-resistant clinical isolates of gram-negative enteric bacilli was compared with that of clavulanate and sulbactam. synergy testing was performed with fixed concentrations of beta-lactamase inhibitors (8 mg/l) combined with doubling dilutions of beta-lactams in microdilution trays. synergy was defi ... | 1986 | 3019984 |
| induction/inhibition of chromosomal beta-lactamases by beta-lactamase inhibitors. | many species of gram-negative bacteria produce chromosomal beta-lactamases that can be induced to high-level expression by exposure to beta-lactam antibiotics. fifty-four strains of escherichia coli, enterobacter, proteus, citrobacter, and morganella were examined for beta-lactamase inducibility by clavulanic acid, sulbactam, ytr 830, ampicillin, and cefoxitin. cefoxitin proved to be the most potent inducer, affecting most of the strains of enterobacter and morganella. clavulanic acid induced 30 ... | 1986 | 3026004 |
| antimicrobial activity of imipenem against 1386 clinical isolates. | 1386 isolates from clinical specimens were tested against imipenem by disc agar diffusion. the bacteria used in this study consisted of escherichia coli, enterobacter aerogenes, e. agglomerans, e. cloacae, klebsiella pneumoniae, k. oxytoca, k. ozanae, proteus mirabilis, p. vulgaris, providencia stuartii, p. rettgeri, acinetobacter calcoaceticus, citrobacter diversus, c. freundii, morganella morganii, serratia liquefaciens, s. marcescens, hafnia alvei, aeromonas hydrophila, pseudomonas aeruginosa ... | 1986 | 3468319 |
| susceptibility of ticarcillin-resistant gram-negative bacilli to different combinations of ticarcillin and clavulanic acid. | the susceptibility of ticarcillin-resistant and of ticarcillin-susceptible gram-negative bacilli to different combinations of ticarcillin and clavulanic acid has been investigated. susceptibility to ticarcillin has been restored in ticarcillin-resistant isolates in proportion to the amount of clavulanic acid in the combination and depending upon the species. the decrease in the mics of ticarcillin was excellent to good in proteus, morganella, providencia, escherichia coli and klebsiella, moderat ... | 1986 | 3636338 |
| effects of environment on infection in burn patients. | burn patients in an early cohort (n = 173) treated in an intensive care ward without separate enclosures were compared with a later cohort (n = 213) treated in a renovated unit with separate bed enclosures. the number of patients developing infection was significantly reduced in the late group. observed mortality was compared with mortality predicted on the basis of burn size and age alone. reduction in observed compared with predicted mortality, inapparent in the early group, was seen in the la ... | 1986 | 3942497 |
| selective and differential medium for the primary isolation of members of the proteeae. | a new differential and selective medium for the isolation of members of the proteeae, pim (proteeae isolation medium) agar, was developed and evaluated. the medium relies on the ability of all members of the proteeae (with the exception of a very few morganella morganii strains) to produce a dark brown pigment in medium containing dl-tryptophan. an additional differential property, tyrosine degradation, was also demonstrated by the medium. members of the proteeae appeared as dark brown colonies ... | 1986 | 3958148 |
| antibiotic resistance and conjugative r plasmids in clinical isolates of enterobacteriaceae in peninsular malaysia. | twenty-five strains of enterobacteria, isolated from man in peninsular malaysia and consisting of seven enterobacter spp., five escherichia coli, five salmonella spp., four klebsiella spp., two shigella spp., one proteus sp. and and one providencia sp., were tested for antibiotic resistance and conjugative r plasmids. they were all sensitive to nalidixic acid and resistant to at least three antibiotics. the number of resistances ranged from 3 to 11 antibiotics, including cefoperazone and sisomic ... | 1986 | 3726978 |
| prevalence and mechanisms of aminoglycoside resistance. a ten-year study. | aminoglycoside resistance was monitored at st. thomas' hospital from 1975 to 1984. gentamicin resistance had appeared in a number of species by 1975, but remained rare (less than 1 percent of isolates) in escherichia coli throughout the study period. gentamicin-resistant klebsielleae had become fairly common (8 percent of isolates) by 1977, but little change has subsequently occurred in their frequency of isolation. serratia species are not frequently isolated; gentamicin resistance in these org ... | 1986 | 3728534 |
| production and degradation of indole by gram-negative bacteria. | the indole reaction is performed in various modifications with regard both to the reagents and to the media used. especially the medium has hitherto attracted little attention and there are divergent recommendations for its composition. the comparison of some broths without and with addition of tryptophan after incubation with different indole-positive species revealed that tryptone without tryptophan yielded stronger reactions than with tryptophan added. other broths showed stronger reactions w ... | 1986 | 3754676 |
| cloning of urease gene sequences from providencia stuartii. | providencia stuartii was the most prevalent isolate recovered from urine specimens taken weekly over a 1-year period from 51 nursing home patients with urinary catheters in place. thirty percent of the isolates were urease positive. urease, which is implicated in renal stone formation, was shown to be transmissible on an 82-kilobase conjugative plasmid in one isolate. plasmid dna isolated from this strain was digested with ecori, ligated into the ecori site of pbr322, and used to transform esche ... | 1986 | 3759233 |
| adherence to uroepithelial cells of providencia stuartii isolated from the catheterized urinary tract. | the long-term catheterized urinary tract appears to offer a niche for providencia stuartii, otherwise an unusual clinical isolate. p. stuartii, the most frequent and persistent isolate from the urine of 51 long-term catheterized patients, was recovered from 761 of 1230 (62%) weekly urine specimens. to test the hypothesis that prevalence of this species may be due to adherence properties of the organism, 20 selected strains from 14 patients at two nursing homes, representing six distinct serotype ... | 1986 | 3625167 |
| synergy of fosfomycin with beta-lactam antibiotics against staphylococci and aerobic gram-negative bacilli. | fosfomycin inhibits bacterial cell wall synthesis at the initial stage. it can act synergistically with beta-lactams. the effect of the combination of fosfomycin and selected penicillins and cephalosporins against staphylococci, pseudomonas aeruginosa, pseudomonas cepacia and selected gram-negative bacteria was determined. synergy was determined by agar dilution and checkerboard titration methods; synergy was defined as an fic index less than or equal to 0.5 and partial synergy greater than 0.5 ... | 1986 | 3569007 |
| inducible type i beta-lactamases of gram-negative bacteria and resistance to beta-lactam antibiotics. | mutants, showing either constitutive (depressed) or non-inducible expression of chromosomally-mediated type i beta-lactamase were obtained from clinical isolates of enterobacter cloacae, ent. aerogenes, citrobacter freundii, providencia stuartii, morganella morganii, serratia marcescens and pseudomonas aeruginosa. the wild-type and mutant strains were compared for susceptibility to a range of beta-lactam antibiotics. derepression of beta-lactamase synthesis generally, but not always, resulted in ... | 1986 | 3485092 |
| the activity of bmy 28142 a new broad spectrum beta-lactamase stable cephalosporin. | the in-vitro activity of bmy 28142, an iminomethoxy, aminothiazolyl cephalosporin containing a methyl pyrrolidinio c-3 was compared with that of cefotaxime, ceftazidime, aztreonam, imipenem and tobramycin against various bacteria. bmy 28142 was the most active agent tested against the enterobacteriaceae inhibiting 90% at less than or equal to 1 mg/l. the in-vitro activity of bmy 28142 was equal to or superior to cefotaxime against the highly susceptible members of the enterobacteriaceae and seve ... | 1986 | 3486862 |
| in-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new beta-lactams. | the in-vitro activity of pefloxacin was compared with that of norfloxacin, enoxacin, nalidixic acid, gentamicin, cefotaxime, ceftazidime and, where appropriate, other beta-lactams against a total of 363 recent clinical isolates. an agar dilution procedure was used to determine mics and two inocula (10(4) and 10(6) cfu) were used throughout. pefloxacin inhibited 90% of isolates of escherichia coli, klebsiella pneumoniae, proteus mirabilis, indole-positive proteus spp., enterobacter spp., shigella ... | 1985 | 3156112 |
| production of brownish pigment by bacteria of the morganella-proteus-providencia group. | all bacteria of the morganella-proteus-providencia group tested produced a brownish pigment on agar containing l-forms of aromatic amino acids, i.e. histidine, phenylalanine, tryptophan, and tyrosine in the presence of iron ions under aerobic conditions. no pigment was observed without iron or when using d-forms of the amino acids. it is a melanin-like pigment with variable molecular weight under about 12000 d and an absorbance maximum between 330 and 410 nm depending on the concentration and th ... | 1985 | 3834717 |
| comparative studies on the structural gene for the ribosomal protein s1 in ten bacterial species. | by applying the southern blot technique we compared the structural gene rpsa for ribosomal protein s1 and its preceding sequence from escherichia coli with nine other bacterial species. we found high homology among the structural genes of e. coli and other gram-negative but not gram-positive bacteria. in contrast, the regulatory sequence preceding the structural gene was not highly conserved among the organisms studied. cloning and dna sequence analysis of a 1.2 kb fragment coding for most of th ... | 1985 | 3862932 |
| in-vitro activity and beta-lactamase stability and inhibitory properties of a new penem antibiotic, sch 34343. | sch 34343 is a new penem antibiotic. its in-vitro activity was determined against gram-positive and -negative aerobic and anaerobic isolates. sch 34343 inhibited 90% of strains of escherichia coli, klebsiella pneumoniae, proteus mirabilis, salmonella spp, citrobacter spp. and shigella spp. at less than 1 mg/1. ninety per cent of strains of enterobacter, morganella and providencia spp. were inhibited by less than 4 mg/1. sch 34343 did not inhibit pseudomonas spp., and it had slightly less activit ... | 1985 | 3875603 |
| multiple antibiotic resistance plasmids in enterobacteriaceae isolated from diarrhoeal specimens of hospitalized children in indonesia. | we studied the plasmid and antibiotic resistance characteristics of 35 strains of enterobacteriaceae recovered from faecal specimens of children with diarrhoea in central general hospital, bandung, indonesia. twenty three escherichia coli, three providencia, three proteus, three klebsiella, two enterobacter and one citrobacter were examined. all strains were multiply resistant, many carrying six to nine antibiotic resistances. most of these resistances were transferable to a laboratory e. coli s ... | 1985 | 3876328 |
| in-vitro activity of the combinations of ampicillin with mecillinam or with beta-lactamase inhibitors against strains resistant to ampicillin. | the in-vitro activity of ampicillin, of mecillinam and of combinations of ampicillin with mecillinam, clavulanic acid or 6 beta-bromopenicillanic acid has been studied against 126 enterobacteriaceae resistant to ampicillin. the combination of ampicillin with mecillinam showed synergy or addition in 60% of the combinations tested. synergy was seen especially when the strains were resistant to mecillinam, indifference when they were susceptible to mecillinam. the combination of ampicillin with mec ... | 1985 | 3879248 |
| the activity of cefbuperazone, a 7 alpha-methoxy 7 beta acyl ureido cephalosporin. | the activity of cefbuperazone, a 7 alpha-methoxy ureido cephalosporin, was determined against 726 clinical isolates. ninety percent of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, citrobacter diversus, proteus mirabilis, enterobacter aerogenes, proteus vulgaris, morganella morganii, salmonella, and shigella species were inhibited by less than or equal to 6.3 micrograms/ml. cefbuperazone was more active than cefamandole, cefoxitin and piperacillin against these species. concentrat ... | 1985 | 3879464 |
| inducible xylitol dehydrogenases in enteric bacteria. | morganella morganii atcc 25829, providencia stuartii atcc 25827, serratia marcescens atcc 13880, and erwinia sp. strain 4d2p were found to induce a xylitol dehydrogenase when grown on a xylitol-containing medium. the xylitol dehydrogenases were partially purified from the four strains, and those from m. morganii atcc 25829, p. stuartii atcc 25827, and s. marcescens atcc 13880 were all found to oxidize xylitol to d-xylulose. these three enzymes had kms for xylitol of 7.1 to 16.4 mm and molecular ... | 1985 | 3886639 |
| in vitro evaluation of current disinfectants for leg bags. | an in vitro study was performed investigating the bactericidal ability of five common cleaning agents for leg bags against organisms frequently causing urinary tract infection in spinal cord injured (sci) patients. individual disposable uridrain leg bags were inoculated with urine containing greater than 10(5) colonies/ml of the selected organism. the organisms used were: pseudomonas aeruginosa, proteus mirabilis, providencia stuartii, klebsiella pneumoniae, serratia marcescens, herellea, and en ... | 1985 | 3886841 |
| gram-negative bacillary infections. pathogenic and pathophysiologic correlates. | gram-negative bacillary infections continue to be extremely important. escherichia coli is the single most frequently encountered pathogen, followed by organisms belonging to the tribe klebsiella-enterobacter-serratia and proteus-providencia. pseudomonas aeruginosa, although it receives considerable (perhaps excessive) attention, is found relatively less frequently, occurring principally in the hospitalized patient who is immunocompromised. many factors, both host and microbial, are responsible ... | 1985 | 3890536 |
| in vitro studies on the antibacterial activities of ym-13115, a new broad-spectrum cephalosporin. | the in vitro antibacterial activities of ym-13115, a new parenteral cephalosporin, were compared with those of ceftazidime, cefoperazone, and cefsulodin. the compound was highly active against the common members of the enterobacteriaceae and 2 to 256 times more active than cefoperazone. ym-13115 was as active as ceftazidime against citrobacter freundii, proteus vulgaris, and morganella morganii and two to four times more active than ceftazidime against escherichia coli, klebsiella pneumoniae, en ... | 1985 | 3890729 |
| clinical evaluation of temocillin in urinary tract infections. | a group of 27 female and 2 male urological patients, aged 19 to 80 years (mean 44 years), were treated with intravenous temocillin 500 mg twice daily for 5 to 7 days. the diagnoses were acute pyelonephritis (n = 20), acute cystitis (n = 6), and acute cystitis and pyelonephritis combined (3). the causative organisms were escherichia coli (n = 20). proteus species (n = 9). klebsiella species (n = 4). streptococcus faecalis (n = 2). staphylococcus epidermidis (n = 1), and providencia stuartii (n = ... | 1985 | 3896736 |
| [clinical evaluation of cefmenoxime in urinary tract and prostatic infections]. | cefmenoxime, a new cephalosporin, was given to fifty patients (28 male and 22 female) aged 15 to 86 years with infection of the urinary tract or prostate. urinary tract infections, i.e. cystitis in 20 cases and pyelonephritis in 21, were usually chronic and associated with urologic anomalies. nine patients had infection of the prostate. pathogens recovered from the urine were 26 e. coli, 8 klebsiella, 16 serratia, 5 proteus mirabilis or indole-positive proteus, 1 providencia, and 4 pseudomonas. ... | 1985 | 3897962 |
| resistance to chloramphenicol in proteus mirabilis by expression of a chromosomal gene for chloramphenicol acetyltransferase. | proteus mirabilis pm13 is a well-characterized chloramphenicol-sensitive isolate which spontaneously gives rise to resistant colonies on solid media containing chloramphenicol (50 micrograms ml-1) at a plating efficiency of 10(-4) to 10(-5). such chloramphenicol-resistant colonies exhibit a novel phenotype with respect to chloramphenicol resistance. when a single colony grown on chloramphenicol agar is transferred to liquid medium and grown in the absence of antibiotic for 150 generations, a pop ... | 1985 | 3900034 |
| [carbenicillin resistance of gram-negative bacteria: incidence, biochemical and genetic determinism]. | of nine hundred ampicillin resistant (amp-r) enterobacteria strains, isolated in hospital between july and december 1981, 73,7% are also carbenicillin-resistant (carb-r). this particular double resistance varies depending upon the species considered: indole positive proteus (23%), enterobacter cloacae (64%), citrobacter freundii (67%), acinetobacter calcoaceticus (73%), proteus mirabilis (75%), serratia marcescens (90%), escherichia coli (91%), providencia stuartii (96%) and klebsiella pneumonia ... | 1985 | 3903620 |
| ceftriaxone: a beta-lactamase-stable, broad-spectrum cephalosporin with an extended half-life. | ceftriaxone is an aminothiazolyl-oxyimino cephalosporin. it possesses the typical in vitro activity of a third-generation cephalosporin with excellent activity against many gram-negative aerobic bacilli: escherichia coli; species of proteus, klebsiella, morganella, providencia and citrobacter; and enterobacter agglomerans. ceftriaxone also has outstanding bactericidal action against pneumococci, group b streptococci, meningococci, gonococci and hemophilus influenzae. in healthy volunteers, it ha ... | 1985 | 3906584 |
| aztreonam therapy for complicated urinary tract infections caused by multidrug-resistant bacteria. | aztreonam was administered to 145 consecutive patients with complicated urinary tract infections caused by multidrug-resistant, aztreonam-sensitive bacteria. multidrug resistance was defined by disk diffusion testing as resistance to aminopenicillins and to first- and second-generation cephalosporins, with or without resistance to aminoglycosides. the first 40 assessable patients received 1 g of aztreonam intravenously three times daily for a median period of eight days; the remaining 95 assessa ... | 1985 | 3909335 |
| [multicenter study of the in vitro effect of imipenem (n-formimidoyl-thienamycin) on hospital bacteria]. | minimal inhibitory concentrations (mics) of imipenem were evaluated by agar dilution for 2 895 bacterial strains isolated in 9 hospitals. imipenem proved highly active against enterobacteriaceae, with an mic less than or equal to 0.25 for 63% of the 1 556 tested strains, less than or equal to 1 for 89.6% and less than or equal to 4 for 99%. the different groups of enterobacteriaceae exhibited similar mode mics (0.12 to 0.25), with the exception of serratia (0.25-0.5), p. mirabilis (0.5), indole- ... | 1985 | 3911142 |