Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| diagnostic performance of the molecular bcr-abl1 monitoring system may impact on inclusion of cml patients in stopping trials. | in chronic myeloid leukemia (cml), the duration of deep molecular response (mr) before treatment cessation (mr4 or deeper, corresponding to bcr-abl1 ≤ 0.01% on the international scale (is)) is considered as a prognostic factor for treatment free remission in stopping trials. mr level determination is dependent on the sensitivity of the monitoring technique. here, we compared a newly established taqman (tm) and our so far routinely used lightcycler (lc) quantitative reverse transcription (qrt)-pc ... | 2019 | 30897165 |
| easy diagnosis of jaundice: a smartphone-based nanosensor bioplatform using photoluminescent bacterial nanopaper for point-of-care diagnosis of hyperbilirubinemia. | one of the concerns of parents in the first days of their baby's birth is the baby's risk of jaundice/hyperbilirubinemia. this is because more than 60% of babies are born with jaundice that, if not timely diagnosed and subsequently treated, can lead to serious damage to their health. on the other hand, despite recent progress in sensor technology for clinical applications, the development of easy-to-use, cost-effective, sensitive, specific, and portable diagnostic devices, which use nontoxic and ... | 2019 | 30896150 |
| a cross-sectional study on the correlation between physical activity levels and health-related quality of life in community-dwelling middle-aged and older adults. | this study aimed to evaluate the association between physical activity level and health-related quality of life in community-dwelling middle aged and older adults in egypt. between may and august 2017, a cross-sectional study of 184 middle-aged and older adults between the ages of 55 and 64 years old (129 males and 55 females) with a mean age of 58 ± 4.3 years old participated in this study. study participants were classified into 3 groups based on their level of physical activity (walking durat ... | 2019 | 30882705 |
| [implementation of the world physical activity day in catalonia]. | even though physical activity (pa) has multiple benefits, 30% of the population is inacti- ve. catalonia impulse the world physical activity day (wpad), as a part of a broader strategy of pa promotion. the objetive of this work was to present the implementation and evolution of wpad from 2010 to 2016. | 2019 | 30880793 |
| the closer the better: does better access to outpatient care prevent hospitalization? | in 2010-2012, new outpatient service locations were established in poor hungarian micro-regions. we exploit this quasi-experiment to estimate the extent of substitution between outpatient and inpatient care. fixed-effects poisson models on individual-level panel data for years 2008-2015 show that the number of outpatient visits increased by 19% and the number of inpatient stays decreased by 1.6% as a result, driven by a marked reduction of potentially avoidable hospitalization (pah) (5%). in our ... | 2019 | 30877400 |
| a tale of two cities: is air pollution improving in paris and london? | paris and london are europe's two megacities and both experience poor air quality with systemic breaches of the no2 limit value. policy initiatives have been taken to address this: some european-wide (e.g. euro emission standards); others local (e.g. low emission zone, lez). trends in nox, no2 and particulate matter (pm10, pm2.5) for 2005-2016 in background and roadside locations; and trends in traffic increments were calculated in both cities to address their impact. trends in traffic counts an ... | 2019 | 30875529 |
| cost-effectiveness of second-line diagnostic investigations in patients included in the dante trial: a randomized controlled trial of lung cancer screening with low-dose computed tomography. | the aim of this study was to analyze the economic efficiency of second-line diagnostic investigations in patients with undetermined lung nodules. | 2019 | 30875336 |
| evaluation of real-world gaseous emissions performance of selective catalytic reduction and diesel particulate filter bus retrofits. | this study reports on the results of gaseous pollutants emission measurements of double-decker buses in an urban road network, using portable emission measurement systems (pems). measured vehicles were tested by following in-service buses on regular routes. six euro ii and euro iii buses were retrofitted with diesel particulate filters (dpf) and selective catalytic reduction (scr) or a combined scr+dpf (scrt) device. substantial and statistically significant technology impacts were observed for ... | 2019 | 30875207 |
| comparative study reveals insights of sheepgrass (leymus chinensis) coping with phosphate-deprived stress condition. | sheepgrass [leymus chinensis (trin.) tzvel] is a valuable forage plant highly significant to the grassland productivity of euro-asia steppes. growth of above-ground tissues of l. chinensis is the major component contributing to the grass yield. although it is generally known that this species is sensitive to ecosystem disturbance and adverse environments, detailed information of how l. chinensis coping with various nutrient deficiency especially phosphate deprivation (-pi) is still limited. here ... | 2019 | 30873190 |
| pilot study on the cost of some oncohematology diseases in bulgaria. | the goal of the current study is to perform a pilot study of the cost of some oncohematology diseases in bulgaria. this is a pilot broader burden of disease research. the official report of the national health insurance fund provided information about the total expenditures paid for medicines, ambulatory services, and hospitalizations in 2015 and 2016. to evaluate the costs from a patient perspective, an internet inquiry was organized with the support of the patient organization. the inquiry con ... | 2019 | 30984734 |
| periprosthetic hip and knee infections: comparison of etiology, perioperative management and costs. | we compared two series of patients treated at our hospital for periprosthetic hip and knee infections (phi; pki), in order to evaluate etiology, perioperative management (duration of spacer, antibiotic therapy, quality of life during the treatment), length of hospital stay, and costs. | 2019 | 30977889 |
| estimating contributions of vehicular emissions to pm2.5 in a roadside environment: a multiple approach study. | vehicular emissions (ve) are among the major sources of airborne fine particulate matter (pm2.5) in urban atmospheres, which adversely impact the environment and public health. receptor models are widely used for estimating pm2.5 source contributions from ve (pmvehicle), but often give inconsistent results due to different modelling principles and assumptions. during december 2015-may 2017, we collected nine-months of hourly organic carbon (oc) and elemental carbon (ec) data, as well as 24-h pm2 ... | 2019 | 30974367 |
| seizures as a complication of recreational drug use: analysis of the euro-den plus data-set. | seizures are a recognized and potentially serious complication of recreational drug use. this study examined a large international data set of presentations to emergency departments with acute recreational drug toxicity, the european drug emergencies plus (euro-den plus) network, to compare presentations with and without seizures and estimate incidence and associated drugs. amongst 23,947 presentations between january 2014 and december 2017, there were 1013 (4.2%) with reported seizures. clinica ... | 2019 | 30974132 |
| influence of cell configuration and long-term operation on electrochemical phosphorus recovery from domestic wastewater. | phosphorus (p) is an important, scarce, and irreplaceable element, and therefore its recovery and recycling are essential for the sustainability of the modern world. we previously demonstrated the possibility of p recovery by electrochemically induced calcium phosphate precipitation. in this article, we further investigated the influence of cell configuration and long-term operation on the removal of p and coremoved calcium (ca), magnesium (mg), and inorganic carbon. the results indicated that t ... | 2019 | 30972262 |
| erratum for euro surveill. 2019;24(13). | 2019 | 30968826 | |
| an economical viable tokamak fusion reactor based on the iter experience. | this is my personal vision and outlook towards a fusion reactor based on my extensive experience from being part of the iter design, and now construction, as well as leading the largest fusion technology program worldwide (kit-karlsruhe institute of technology) for 7 years. in particular, i want to discuss how a fusion reactor can be economically viable without employing too advanced physics and technology. it certainly will be a pulsed machine (approx. 20 000 s pulses) with thermal energy stora ... | 2019 | 30967048 |
| [what do mri and ct scan provide us in patients with vertigo and dizziness? a cost-utility analysis]. | vertigo and dizziness are symptoms with a significant burden in the hospital and involve several specialties. there are few guidelines of radiological tests for these symptoms. | 2019 | 30963529 |
| hospitalization cost reduction with sacubitril-valsartan implementation in a cohort of patients from the daunia heart failure registry. | aim of this study was to assess the impact of the introduction of new class of drugs (arni: angiotensin receptor-neprilysin inhibitor) on hospital related costs in a real world cohort of patients with chronic heart failure (chf). | 2019 | 30963090 |
| healthcare-associated infections due to multidrug-resistant organisms: a surveillance study on extra hospital stay and direct costs. | the increasing antimicrobial resistance poses a challenge to surveillance systems and raises concerns about the impact of multidrug-resistant organisms on patient safety. | 2019 | 30961489 |
| the esc-eorp euro-endo (european infective endocarditis) registry. | the european society of cardiology (esc) eurobservational research programme (eorp) european endocarditis (euro-endo) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (ie) and compare findings with recommendations from the 2015 esc clinical practice guidelines for the management of ie and data from the 2001 euro heart survey. | 2019 | 30957862 |
| blocking representation in the era-interim driven euro-cordex rcms. | while regional climate models (rcms) have been shown to yield improved simulations compared to general circulation model (gcm), their representation of large-scale phenomena like atmospheric blocking has been hardly addressed. here, we evaluate the ability of rcms to simulate blocking situations present in their reanalysis driving data and analyse the associated impacts on anomalies and biases of european 2-m air temperature (tas) and precipitation rate (pr). five rcm runs stem from the euro-cor ... | 2019 | 30956409 |
| patient and caregiver productivity loss and indirect costs associated with cardiovascular events in europe. | the aim of this study was to estimate patient and caregiver productivity loss and indirect costs following an acute coronary syndrome (acs) or a stroke in europe. | 2019 | 30955367 |
| assessment of pm2.5 and pah content in pm2.5 emitted from mobile source gasoline-fueled vehicles in concomitant with the vehicle model and mileages. | this study investigates the pm2.5 emission and analyses the pahs content in pm2.5 emitted from gasoline-fueled vehicles. outflow from the vehicles appear to be the ultimate source of pahs in metro urban communities since the emission from gasoline vehicle increases the wellbeing hazard due to contiguity of exposure to gasoline exhaust. in this study, fifteen vehicles were randomly taken for sampling, where sixteen priority pahs concentration were investigated. the study was performed on the vehi ... | 2019 | 30953895 |
| phylogenetic analysis of mycobacterium tuberculosis strains in wales by use of core genome multilocus sequence typing to analyze whole-genome sequencing data. | an inability to standardize the bioinformatic data produced by whole-genome sequencing (wgs) has been a barrier to its widespread use in tuberculosis phylogenetics. the aim of this study was to carry out a phylogenetic analysis of tuberculosis in wales, united kingdom, using ridom seqsphere software for core genome multilocus sequence typing (cgmlst) analysis of whole-genome sequencing data. the phylogenetics of tuberculosis in wales have not previously been studied. sixty-six mycobacterium tube ... | 2019 | 30944195 |
| how to harness big data for the benefit of patients. | imi is a large public private partnership which has committed euro 5 billion from the european commission, the european pharmaceutical sector and other partners, to enable and accelerate bringing medical innovation to patients. imi is now 10 years old and already has changed the ecosystem and way of working in developing innovative medicines across the public/private divide. big data represents a significant piece of this investment and projects in this area are attempting to provide solutions t ... | 2019 | 30942701 |
| predictors and burden of hospital readmission with recurrent clostridioides difficile infection: a french nation-wide inception cohort study. | to investigate the predictors and burden of hospital readmission with recurrent clostridioides difficile infection (rcdi) in a large european healthcare system with a low prevalence of hyper-virulent c. difficile clones. we conducted an inception cohort study based on an exhaustive health insurance database and including all survivors of a first hospital stay with cdi over a one-year period (2015) in france. readmissions with rcdi were defined as a novel hospital stay with cdi within 12 weeks fo ... | 2019 | 30941532 |
| healthcare resource utilisation and cost associated with elevated potassium levels: a danish population-based cohort study. | to investigate healthcare costs associated with hyperkalaemia (hk) among patients with chronic kidney disease (ckd), heart failure (hf) or diabetes. | 2019 | 30940761 |
| cyclosporine in resistant systemic arthritis - a cheaper alternative to biologics. | to assess the efficacy of cyclosporine (csa) in patients of oral steroid unresponsive or steroid dependent systemic juvenile idiopathic arthritis (sjia); to evaluate the optimum dosage and blood level of csa to achieve and maintain remission and to observe for side-effects on prolonged usage. | 2019 | 30937723 |
| early unplanned reoperations after gastrectomy for gastric cancer are different between laparoscopic surgery and open surgery. | to compare the differences in occurrence rates, time intervals, main causes, and management strategies of early unplanned reoperations (euros) after gastrectomy for gastric cancer (gc) between laparoscopic and open surgery. | 2019 | 30937616 |
| possession in football: more than a quantitative aspect - a mixed method study. | the aim of the present study was to identify and differentiate the factors that determine the possession times of successful and unsuccessful elite football teams, with the purpose of identifying a more effective possession model. for this, match corresponding to the round of eighth-finals, quarter-finals, semi-finals and final of the 2016 uefa euro france in which 2,636 offensive sequences occurred, were analyzed. video recordings of matches were analyzed and coded post-event using systematic o ... | 2019 | 30936844 |
| cost-effectiveness of the copd patient management european trial home-based disease management program. | efficient management of copd represents an international challenge. effective management strategies within the means of limited health care budgets are urgently required. this analysis aimed to evaluate the cost-effectiveness of a home-based disease management (dm) intervention vs usual management (um) in patients from the copd patient management european trial (comet). | 2019 | 30936689 |
| a statistical model of cleavage fracture toughness of ferritic steel din 22nimocr37 at different temperatures. | it is a conventional practice to adopt weibull statistics with a modulus of 4 for characterizing the statistical distribution of cleavage fracture toughness of ferritic steels, albeit based on a rather weak physical justification. in this study, a statistical model for cleavage fracture toughness of ferritic steels is proposed according to a new local approach model. the model suggests that there exists a unique correlation of the cumulative failure probability, fracture toughness and yield stre ... | 2019 | 30934560 |
| vertigo and dizziness cause considerable more health care resource use and costs: results from the kora ff4 study. | vertigo is a common reason for primary care consultations, and its diagnosis and treatment consume considerable medical resources. however, limited information on the specific cost of vertigo is currently available. the aim of this study is to analyse the health care costs of vertigo and examine which individual characteristics would affect these costs. | 2019 | 31119449 |
| dental extractions for patients on oral antiplatelet: a within-person randomised controlled trial comparing haemostatic plugs, advanced-platelet-rich fibrin (a-prf+) plugs, leukocyte- and platelet-rich fibrin (l-prf) plugs and suturing alone. | to compare the outcome of tooth extractions in patients taking oral antithrombotic without reducing their dose. four different interventions were compared within the same patient: suturing alone (control group), suturing plus a haemostatic plug, suturing plus advanced-platelet-rich fibrin (a-prf+) plug, and suturing plus leukocyte- and platelet-rich fibrin (l-prf) plug into the socket. | 2019 | 31116189 |
| the economic value of time of informal care and its determinants (the cuidarse study). | the main aims of this paper are to analyse the monetary value of informal care time using different techniques and to identify significant variables associated with the number of caregiving hours. | 2019 | 31112587 |
| depression and incidence of frailty in older people from six latin american countries. | frailty and depression are highly comorbid conditions, but the casual direction is unclear and has not been explored in low- and middle-income countries. the aim of this study was to investigate the potential impact of depression on incident frailty in older people living in latin america. | 2019 | 31109899 |
| a forward collision avoidance algorithm based on driver braking behavior. | measuring risk is critical for collision avoidance. the paper aims to develop an online risk level classification algorithm for forward collision avoidance systems. assuming risk levels are reflected by braking profiles, deceleration curves from critical evasive braking events from the virginia "100-car" database were first extracted. the curves are then clustered into different risk levels based on spectrum clustering, using curve distance and curve changing rate as dissimilarity metrics among ... | 2019 | 31103877 |
| 1st enmc european meeting: the euro-nmd pathology working group recommended standards for muscle pathology amsterdam, the netherlands, 7 december 2018. | 2019 | 31101462 | |
| "i worry if i will have food tomorrow": a study on food insecurity among asylum seekers living in norway. | high prevalence of food insecurity has been observed among asylum seekers resettled in high-income countries. economic constraints, lack of knowledge about new foods, difficulties with shopping, challenges with language, as well as problems complying with various religious food rules are associated with the occurrence and severity of food insecurity. however, no data on food security among asylum seekers in norway currently exist. thus, the aim of the study was to assess food security among asyl ... | 2019 | 31101092 |
| [return to work after temporary disability pension]. | in germany, there are no statistics available that reveal how many temporary disability pensioners return to work. the aim of this study was to analyse how many persons to whom a temporary disability pension was granted in 2006 returned to work. their socio-demographic, health-related and vocational characteristics were examined. | 2019 | 31100762 |
| effectiveness and safety/tolerability of eslicarbazepine acetate in epilepsy patients aged ≥ 60 versus < 60 years: a subanalysis from the euro-esli study. | clinical practice studies help guide antiepileptic drug (aed) therapy in patient groups routinely excluded from clinical trials, such as the elderly. the euro-esli study investigated the effectiveness and safety/tolerability of eslicarbazepine acetate (esl) when used in everyday clinical practice in europe. a subanalysis of data from elderly patients (≥ 60 years) included in the euro-esli study was conducted to assess these aspects of esl use in this population. | 2019 | 31098888 |
| european commission kills billion-euro flagship concept. | 2019 | 31097646 | |
| cost-effectiveness of intrapleural use of tissue plasminogen activator and dnase in pleural infection: evidence from the mist2 randomised controlled trial. | the mist2 (second multicentre intrapleural sepsis trial) trial showed that combined intrapleural use of tissue plasminogen activator (t-pa) and recombinant human dnase was effective when compared with single agents or placebo. however, the treatment costs are significant and overall cost-effectiveness of combined therapy remains unclear.an economic evaluation of the mist2 trial was performed to assess the cost-effectiveness of combined therapy. costs included were those related to study medicati ... | 2019 | 31097519 |
| the "heart valve clinic" pathway for the management of frail patients with valvular heart disease: from "one for all" to "all for one". | valvular heart disease (vhd) is frequently diagnosed in old patients with clinical evidence of heart failure. this elderly population typically presents a high prevalence of frailty and comorbidities, which are associated with increased operative risk for surgical and percutaneous procedures. recently, the euro heart survey reported a clear gap between treatment guidelines and their application in the "real world". a more realistic approach to the treatment of older vhd patients treatment, mostl ... | 2019 | 31094730 |
| strong temperature dependence for light-duty diesel vehicle no x emissions. | diesel-powered road vehicles are important sources for nitrogen oxide (no x) emissions, and the european passenger fleet is highly dieselised, which has resulted in many european roadside environments being noncompliant with legal air quality standards for nitrogen dioxide (no2). on the basis of vehicle emission remote sensing data for 300000 light-duty vehicles across the united kingdom, light-duty diesel no x emissions were found to be highly dependent on ambient temperature with low temperatu ... | 2019 | 31094196 |
| indications for percutaneous coronary intervention (pci) in chronic total occlusion (cto): have we reached a decision or do we continue to explore after euro-cto? | a coronary chronic total occlusion (cto) is a common finding during coronary angiography and is associated with increased mortality and poorer cardiovascular prognosis. technological developments in percutaneous strategies for revascularisation have resulted in increased interest in this area. however, until recently, there has been a paucity of robust scientific randomised data comparing the efficacy of medical management with percutaneous strategies. both observational data, and to a lesser ex ... | 2019 | 31078427 |
| out-of-pocket payments, vertical equity and unmet medical needs in france: a national multicenter prospective study on lymphedema. | out-of-pocket payments might threaten the vertical equity of financing and generate unmet medical needs. the main objective was to assess the vertical equity of outpatient out-of-pocket payments for lymphedema patients in france. twenty-seven centres, among which 11 secondary care hospitals and 16 primary care practices participated in this prospective national multicenter study. we measured the lymphedema-specific outpatient out-of-pocket payments over 6 months. the vertical equity of out-of-po ... | 2019 | 31067244 |
| an eight-year epidemiologic study of head and neck tuberculosis in texas, usa. | head and neck tuberculosis (hntb) especially cervical lymphadenopathy are the most common extrapulmonary indications of tb, but remain a diagnostic challenge. in this study, we describe and analyze the epidemiologic characteristics of hntb on a population-level. | 2019 | 31060959 |
| safety of intradiscal delivery of triamcinolone acetonide by a poly(esteramide) microsphere platform in a large animal model of intervertebral disc degeneration. | local corticosteroids have been used to relieve symptoms of chronic low back pain, although treatment effects have been shown to wear off relatively fast. prolonging corticosteroid presence by controlled release from biomaterials may allow for longer pain relief while circumventing adverse effects such as high bolus dosages. | 2019 | 31056104 |
| family-based activity settings of children in a low-income african context. | there has been an overwhelming call to improve the understanding of how children develop within an african context as euro-american definitions of competence have been uncritically adopted as the norm for children in africa. the activities that children engage in within the family setting are seen as important to understand how children develop within context. the use of activity settings is closely aligned with a strengths-based perspective of family-centred practice and contributes to improved ... | 2019 | 31049305 |
| the sustainable impact of an educational approach to improve the appropriateness of laboratory test orders in the icu. | few studies described strategies to improve the use of diagnostic tests in intensive care units (icu). no study assessed whether their impact was sustained or not. in this study, we assessed whether a multi-faceted intervention for more appropriate use of laboratory testing can decrease the number of tests, is sustainable, is not associated with additional morbidity and represents a potential cost saving. | 2019 | 31042718 |
| cross-cultural affective neuroscience. | panksepp, the father of affective neuroscience, dedicated his life to demonstrate that foundations of mental life and consciousness lay in the archaic layers of the brain. he had an evolutionary perspective emphasizing that the subcortical affective systems come prior to cortical cognitive systems. based on his life-long work, the affective neuroscience personality scales (anps) was constructed, and a new neurodevelopmental approach to personality was started. the new approach suggested that per ... | 2019 | 31037064 |
| health outcomes and unmet needs in patients with long-standing rheumatoid arthritis attending tertiary care in greece: a cohort study. | no previous studies have characterized a patient's experience of rheumatoid arthritis (ra) management in greece and unmet needs may exist despite a broad range of available treatments. therefore, we assessed quality of life (qol), functional ability, and healthcare resource utilization in patients with established ra and receiving treatment in a tertiary care setting in greece. | 2019 | 31036012 |
| how anesthetic, analgesic and other non-surgical techniques during cancer surgery might affect postoperative oncologic outcomes: a summary of current state of evidence. | the question of whether anesthetic, analgesic or other perioperative intervention during cancer resection surgery might influence long-term oncologic outcomes has generated much attention over the past 13 years. a wealth of experimental and observational clinical data have been published, but the results of prospective, randomized clinical trials are awaited. the european union supports a pan-european network of researchers, clinicians and industry partners engaged in this question (cost action ... | 2019 | 31035321 |
| particle emissions of euro vi, eev and retrofitted eev city buses in real traffic. | exhaust emissions from traffic significantly affect urban air quality. in this study, in-traffic emissions of diesel-fueled city buses meeting enhanced environmentally friendly vehicle (eev) and euro vi emission limits and the effects of retrofitting of eev buses were studied on-road by chasing the buses with a mobile laboratory in the helsinki region, finland. the average emission factors of particle number (pn), particle mass (pm1) and black carbon mass (bc) were 0.86·1015 1/kgfuel, 0.20 g/kgf ... | 2019 | 31035153 |
| cultural perspectives on positive responses to extreme adversity: a playing field for metaphors. | in euro-american societies, "resilience" and "post-traumatic growth" are commonly used metaphorical terms for positive responses to extreme adversity. however, research on illness narratives has demonstrated that other cultures may have different metaphorical concepts that act as vehicles for shared beliefs about how to overcome extreme adversity or traumatic experiences. the purpose of this article is to identify metaphors used in various cultures to describe positive responses to extreme adver ... | 2019 | 31027474 |
| fluoroquinolone-related adverse events resulting in health service use and costs: a systematic review. | adverse events (aes) associated with the use of fluoroquinolone antimicrobials include clostridium difficile associated diarrhea (cdad), liver injury and seizures. yet, the economic impact of these aes is seldom acknowledged. the aim of this review was to identify health service use and subsequent costs associated with ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin -related aes. | 2019 | 31026286 |
| molecular detection of mycobacterium tuberculosis sensitivity to rifampicin and isoniazid in south gondar zone, northwest ethiopia. | drug resistant tuberculosis (tb) has become a persistent health threat in ethiopia. in this respect, baseline data are scarce in many parts of high tb burden regions including the different zones of ethiopia. | 2019 | 31023267 |
| predicting hydrologic flows under climate change: the tâmega basin as an analog for the mediterranean region. | the potential effects of climate change on the hydrology of the tâmega river basin, northern portugal, are assessed by comparing simulated hydrologic scenarios derived from both observational climate databases for a recent past period (1950-2015) and euro-cordex model simulations for the future (2021-2100). future climate change scenarios are based on an ensemble of five climate model chain experiments and on two representative concentration pathways (rcp4.5 and rcp8.5). basin-mean annual temper ... | 2019 | 31018443 |
| author's correction for euro surveill. 2019;24(14). | 2019 | 31017085 | |
| the management of type 2 diabetes with once-weekly semaglutide versus dulaglutide: a long-term cost-effectiveness analysis in slovakia. | glucagon-like peptide-1 (glp-1) receptor agonists represent a class of treatments for type 2 diabetes that offer multifactorial benefits, including glycemic control, weight loss and low hypoglycemia risk. once-weekly semaglutide is a novel glp-1 analog that has been associated with improved glycemic control and reduced body mass index (bmi) versus once-weekly glp-1 receptor agonist dulaglutide in sustain 7, which is reimbursed in patients with a bmi > 35 kg/m2 in slovakia. the aim of the present ... | 2019 | 31168765 |
| conceptual assessment of energy input-output analysis and data envelopment analysis of greenhouse crops in crete island, greece. | the current study observes the input/output energy quantities and its associated financial value, in vegetable greenhouses on crete, greece, for the 2015-2016 cropping seasons. the utilized data was taken in regular direct basis for the implementation of energy input-output analysis and data envelopment analysis. for input data analysis, four crop practices were used tomato, pepper, cucumber, and eggplant. the outcomes of the expended majority of energy input-output analysis showed that fertiliz ... | 2019 | 31168717 |
| pure stress urinary incontinence: analysis of prevalence, estimation of costs, and financial impact. | the prevalence of pure stress urinary incontinence (p-sui) and the role of urodynamic investigation (udi) prior to surgery for stress urinary incontinence (sui) is debated. since the exact prevalence of p-sui is not clear, its clinical and economic impact is not well defined. the aims of this study were to evaluate the prevalence of p-sui in a population of women who underwent udi for urinary incontinence (ui), also assessing: 1) the correspondence between clinical diagnosis of p-sui and urodyna ... | 2019 | 31164133 |
| a pre-miocene irano-turanian cradle: origin and diversification of the species-rich monocot genus gagea (liliaceae). | the irano-turanian (it) floristic region is considered an important center of origin for many taxa. however, there is a lack of studies dealing with typical it genera that also occur in neighboring areas. the species-rich monocot genus gagea salisb. shows a center of diversity in it region and a distribution in adjacent regions, therefore representing a good study object to investigate spatial and temporal relationships among it region and its neighboring areas (east asia, euro-siberia, himalaya ... | 2019 | 31161005 |
| re: "associations of electric shock and extremely low-frequency magnetic field exposure with the risk of amyotrophic lateral sclerosis: the euro-motor project". | 2019 | 31150043 | |
| medical assessment of potential concussion in elite football: video analysis of the 2016 uefa european championship. | the objective is to determine if suspected concussions in elite football are medically assessed according to the international conferences on concussion in sport consensus statement recommendations. | 2019 | 31147360 |
| targeted temperature management in patients undergoing extracorporeal life support after out-of-hospital cardiac arrest: an euro-elso 2018 annual conference survey. | targeted temperature management and extracorporeal life support, particularly extracorporeal membrane oxygenation in patients undergoing cardiopulmonary resuscitation, represent outcome-enhancing strategies for patients following in- and out-of-hospital cardiac arrest. although targeted temperature management with hypothermia between 32°c and 34°c and extracorporeal cardiopulmonary resuscitation bear separate potentials to improve outcome after out-of-hospital cardiac arrest, each is associated ... | 2019 | 31146629 |
| characterisation of diesel vehicle emissions and determination of remote sensing cutpoints for diesel high-emitters. | diesel vehicles are a major source of air pollutants in cities and have caused significant health risks to the public globally. this study used both on-road remote sensing and transient chassis dynamometer to characterise emissions of diesel light goods vehicles. a large sample size of 183 diesel vans were tested on a transient chassis dynamometer to evaluate the emission levels of in-service diesel vehicles and to determine a set of remote sensing cutpoints for diesel high-emitters. the results ... | 2019 | 31146236 |
| pelvic floor sensations after the first vaginal delivery: a qualitative study. | current validated instruments to screen for pelvic organ prolapse and its sequelae address bulge symptoms, bowel and bladder changes, and sexual intimacy. however, sensitivity is lower in younger women, and there is no instrument specifically designed to screen in postpartum, primiparous women for early changes, that is, changes that may be noticed before the symptom of a bulge or signs of pelvic organ prolapse occur. our goal was to elucidate early sensations of pelvic floor support changes in ... | 2019 | 31145228 |
| [long-term health effects of earthquakes: outlining the features of an epidemiological surveillance system in italy.] | the major earthquakes occurred in italy in the past 10 years (l'aquila, emilia and amatrice) have resulted in 679 death, displacement of more than 120,000 people and economic losses for more than 20 billion euros. in a recent review, we found that earthquakes are associated to multiple health conditions in the long term. because of italy's high seismic risk, it is likely that establishing a post-earthquake surveillance system would enable early detection of many deleterious effects and mitigatio ... | 2019 | 31140451 |
| eslicarbazepine acetate in epilepsy patients with psychiatric comorbidities and intellectual disability: clinical practice findings from the euro-esli study. | psychiatric and intellectual comorbidities are common in patients with epilepsy. however, data on the use of antiepileptic drugs in these patients are still lacking. this study assessed the real-world effectiveness and safety/tolerability of eslicarbazepine acetate (esl) in patients with intellectual disability and psychiatric comorbidities, including a separate analysis specifically in those with depression, using data from the euro-esli study. effectiveness measures included responder and seiz ... | 2019 | 31128460 |
| addendum for euro surveill. 2019;24(22). | 2019 | 31186077 | |
| cost of hospital care for the older adults according to their level of frailty. a cohort study in the lazio region, italy. | the increasing burden of chronic diseases associated with the ageing of the european population constitutes one of the main challenges for the welfare systems in developed western countries, especially through its impact on the use of hospital services and the cost of care. this study aims at evaluating the cost of hospital care for older adults living in the lazio region, italy, according to their level of frailty. | 2019 | 31185033 |
| real-time automatic calculation of euro coins and banknotes in a cash drawer. | a very interesting and useful complement to classical cash-registers is presented in this paper, coming up with a real-time auto-counting solution for the money inside a cash drawer. the system allows knowing not only the total amount of money but also how many coins and banknotes there are of each value. the embedded solution developed has been intended to become a low-cost solution, allowing better control over the money and helping both owners and workers in the establishments. by using this ... | 2019 | 31181860 |
| important outcomes of moral case deliberation: a euro-mcd field survey of healthcare professionals' priorities. | there is a lack of empirical research regarding the outcomes of such clinical ethics support methods as moral case deliberation (mcd). empirical research in how healthcare professionals perceive potential outcomes is needed in order to evaluate the value and effectiveness of ethics support; and help to design future outcomes research. the aim was to use the european moral case deliberation outcome instrument (euro-mcd) instrument to examine the importance of various mcd outcomes, according to he ... | 2019 | 31320403 |
| how does mental health stigma get under the skin? cross-sectional analysis using the health survey for england. | despite increased awareness of mental health problems, stigma persists. little research has examined potential health and wellbeing outcomes associated with stigma. the aim of this study was to investigate relationships between mental health stigma, metabolic and cardiovascular biomarkers, as well as wellbeing and quality of life among people with no mental disorder, common mental disorders and severe mental illness. data were taken from adults aged 16 + years participating in the health survey ... | 2019 | 31312714 |
| scenarios for population health inequalities in 2030 in europe: the euro-healthy project experience. | health inequalities have been consistently reported across and within european countries and continue to pose major challenges to policy-making. the development of scenarios regarding what could affect population health (ph) inequalities across europe in the future is considered critical. scenarios can help policy-makers prepare and better cope with fast evolving challenges. | 2019 | 31238946 |
| genomic characterization of mdr/xdr-tb in kazakhstan by a combination of high-throughput methods predominantly shows the ongoing transmission of l2/beijing 94-32 central asian/russian clusters. | kazakhstan remains a high-burden tb prevalence country with a concomitent high-burden of multi-drug resistant tuberculosis. for this reason, we performed an in depth genetic diversity and population structure characterization of mycobacterium tuberculosis complex (mtc) genetic diversity in kazakhstan with both patient and community benefit. | 2019 | 31234780 |
| genetic diversity and drug susceptibility profiles of mycobacterium tuberculosis obtained from saint peter's tb specialized hospital, ethiopia. | tuberculosis (tb) is one of the major public health problems in ethiopia. data on genetic diversity and resistance profile of circulating tb strains is critical for informing the national tb control program. | 2019 | 31233535 |
| impact of clinical ethics support on daily practice-first-line managers' experiences in the euro-mcd project. | to explore first-line managers' experiences of what moral case deliberation has meant for daily practice, to describe perceptions of context influence and responsibility to manage ethically difficult situations. | 2019 | 31220384 |
| the impact of medication review with version 2 stopp (screening tool of older person's prescriptions) and start (screening tool to alert doctors to right treatment) criteria in a french nursing home: a 3-month follow-up study. | improving medication appropriateness is a priority of french national campaigns in nursing homes. a pilot study was conducted to evaluate the impact of a medication review in a french nursing home with a 3-month follow up. | 2019 | 31217947 |
| long term cost-minimization analysis of robot-assisted hysterectomy versus conventional laparoscopic hysterectomy. | the aim of this study is to carry out the economic evaluation, in term of a cost-minimization analysis that considers healthcare costs and indirect costs, of robot-assisted hysterectomy (rah) compared with conventional laparoscopic hysterectomy (clh) in female adults scheduled for total laparoscopic hysterectomy for benign conditions. | 2019 | 31214891 |
| unveiling the diversity of immunoglobulin heavy constant gamma (ighg) gene segments in brazilian populations reveals 28 novel alleles and evidence of gene conversion and natural selection. | even though immunoglobulins are critical for immune responses and human survival, the diversity of the immunoglobulin heavy chain gene (igh) is poorly known and mostly characterized only by serological methods. moreover, this genomic region is not well-covered in genomic databases and genome-wide association studies due to particularities that impose technical difficulties for its analysis. therefore, the igh gene has never been systematically sequenced across populations. here, we deliver an un ... | 2019 | 31214166 |
| a rapid viability and drug-susceptibility assay utilizing mycobacteriophage as an indicator of drug susceptibilities of anti-tb drugs against mycobacterium smegmatis mc2 155. | a rapid in-house tm4 mycobacteriophage-based assay, to identify multidrug resistance against various anti-tuberculosis drugs, using the fast-growing mycobacterium smegmatis mc2 155 in a microtiter plate format was evaluated, based on phage viability assays. | 2019 | 31210153 |
| daimondna: a portable, low-cost loop-mediated isothermal amplification platform for naked-eye detection of genetically modified organisms in resource-limited settings. | the steady increase in commercialization of genetically modified organisms (gmos) demands low-cost, rapid and portable gmo-detection methods that are technically and economically sustainable. traditional nucleic acid detection platforms are still expensive, immobile and generate complex read-outs to be analyzed by experienced personal. herein, we report the development of a portable, rapid and user-friendly gmo-detection biosensor, daimondna. the system specifically amplifies the target dna usin ... | 2019 | 31207569 |
| cost effectiveness of lifelong therapy with pcsk9 inhibitors for lowering cardiovascular events in patients with stable coronary artery disease: insights from the ludwigshafen risk and cardiovascular health cohort. | proprotein convertase subtilisin/kexin type 9 inhibitors (pcsk9i) reduce cardiovascular events in coronary artery disease (cad). their costs exceed that of established oral lipid-lowering agents. previous cost-effectiveness assessments have been inconsistent. markov cohort state transitions models for stable cad patients were calculated using information from 1530 participants of the ludwigshafen risk and cardiovascular health study (luric) with known causes of deaths. non-fatal to fatal event r ... | 2019 | 31207358 |
| the orthotospovirus nonstructural protein nss suppresses plant myc-regulated jasmonate signaling leading to enhanced vector attraction and performance. | pandemics of vector-borne human and plant diseases often depend on the behaviors of their arthropod vectors. arboviruses, including many bunyaviruses, manipulate vector behavior to accelerate their own transmission to vertebrates, birds, insects, and plants. however, the molecular mechanism underlying this manipulation remains elusive. here, we report that the non-structural protein nss of tomato spotted wilt orthotospovirus, a prototype of the tospoviridae family and the orthotospovirus genus, ... | 2019 | 31206553 |
| physical violence during pregnancy in france: frequency and impact on the health of expectant mothers and new-borns. | objectives even during pregnancy women may suffer from violence. we estimated the prevalence of physical abuse during pregnancy, we analyzed the main risk factors and described the relationship between physical violence, psychological wellbeing and pregnancy outcome. methods we used a national representative sample of births, in all public and private maternity units, in 2016 in france. women were interviewed after delivery, on their living conditions and occurrence of physical violence at least ... | 2019 | 31203524 |
| the eq-5d-5l in patients admitted to a hospital in japan with recent spinal cord injury: a descriptive study. | descriptive study. | 2019 | 31201371 |
| the economic value of mussel farming for uncertain nutrient removal in the baltic sea. | mussel farming has been recognised as a low cost option for mitigating damage caused by eutrophication in the baltic sea. however, uncertain nutrient removal owing to weather and environmental conditions at the mussel farm site has not been previously considered. the purpose of this study was to estimate whether mussel farming has cost advantages even in conditions of uncertainty. to this end, the replacement cost method was used for the valuation of ecosystem services and a numerical cost minim ... | 2019 | 31199831 |
| spatial risk adjustment between health insurances: using gwr in risk adjustment models to conserve incentives for service optimisation and reduce maup. | this paper presents a new approach to deal with spatial inequalities in risk adjustment between health insurances. the shortcomings of non-spatial and spatial fixed effects in risk adjustment models are analysed and opposed against spatial kernel estimators. theoretical and empirical evidence suggests that a reasonable choice of the spatial kernel could limit the spatial uncertainty of the modifiable area unit problem under heavy-tailed claims data, leading to more precise predictions and econom ... | 2019 | 31197612 |
| blood, race and indigenous peoples in twentieth century extreme physiology. | in the first half of the twentieth century the attention of american and european researchers was drawn to the area of 'extreme physiology', partly because of expeditions to the north and south poles, and to high altitude, but also by global conflicts which were fought for the first time with aircraft, and involved conflict in non-temperate zones, deserts, and at the freezing eastern front. in an attempt to help white euro-americans survive in extreme environments, physiologists, anthropologists ... | 2019 | 31197607 |
| exploring the "latin american mediterranean" family and the rdrio lineage in mycobacterium tuberculosis isolates from paraguay, argentina and venezuela. | the latin american & mediterranean (lam) spoligotype family is one of the most successful genotype of mycobacterium tuberculosis worldwide and particularly prevalent in south-america. within this family, a sublineage named region of difference rio (rdrio) was reported initially in brazil and is characterized by a genomic deletion of about 26.3 kb. this lineage seems to show a specific adaptation to the euro-latin american population. in this context, we sought to evaluate the lam family and the ... | 2019 | 31195979 |
| rejections in an non-purpose bred assistance dog population: reasons, consequences and methods for screening. | assistance dogs aid people with various impairments on a daily basis. to become an assistance dog, a strict selection procedure and intensive training period must be successfully completed. consequently, not every dog acquired for this purpose, becomes an assistance dog. the purpose of this study was to investigate reasons for failure and the financial consequences thereof for assistance dog associations that do not have a dedicated breeding program for their dogs. data were collected for a tota ... | 2019 | 31194832 |
| predictors of health-related quality of life among patients with type ii diabetes mellitus who are insulin users: a multidimensional model. | diabetes mellitus is a progressive, chronic and multifactorial endocrine disorder characterized by elevated serum glucose levels. it has a direct effect to social and health related quality of life. | 2019 | 31193026 |
| patient-centered involvement in decision-making: ethnic group and sex as indicators of patients' preferences and perceptions. | ideally, doctors ask each patient's current views about involvement in decision-making, but inquiries prove inconclusive with some inpatients. doctors may then need indirect indicators of those views. we, therefore, explored ethnic group and sex as cultural indicators of patients' current preferences and perceptions about such involvement. | 2019 | 31192891 |
| power dynamics in catholic parishes shared by latinos. | the national study of catholic parishes with hispanic ministry confirmed that most latino catholics share their parish with another cultural group, usually euro-american whites. the presence of multiple ethnic or racial groups in a single parish inevitably draws attention to the power relationships between those groups. data reveal an emerging majority of latino catholics in the united states, yet demographic status does not necessarily translate to increased influence in parishes. latino cathol ... | 2019 | 31307338 |
| cost-effectiveness analysis of erenumab versus onabotulinumtoxina for patients with chronic migraine attacks in greece. | migraine is a common, chronic neurovascular brain disorder with non-negligible multifaceted economic costs. existing preventive treatments involve the selective use of onabotulinumtoxina, which aims at migraine morbidity reduction for patients who have failed initial preventive treatment with oral agents. erenumab is a new preventive treatment for migraines. | 2019 | 31302899 |
| clinical relevance of ethanol coingestion in patients with ghb/gbl intoxication. | ethanol intake can increase the sedative effects of gamma-hydroxybutyrate/gamma-butyrolactone (ghb/gbl), although the real clinical impact is unknown. we studied the clinical impact of the co-ingestion of ethanol in patients presenting to the emergency department (ed) with acute toxicity related to ghb/gbl use. | 2019 | 31301370 |
| insight into genetic diversity of mycobacterium tuberculosis in kandy, sri lanka reveals predominance of the euro-american lineage. | sri lanka is a country where the molecular epidemiology of mycobacterium tuberculosis (mtb) is poorly explored. therefore, this study was performed to identify circulating lineages/sub-lineages of mtb and their transmission patterns. | 2019 | 31299365 |