Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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control of root-knot nematodes on tomato in stone wool substrate with biological nematicides. | the efficacy of four biological nematicides on root-galling, root-knot nematode (meloidogyne incognita) reproduction, and shoot weight of tomato (solanum lycopersicum) grown in stone wool substrate or in pots with sandy soil was compared to an oxamyl treatment and a non-treated control. in stone wool grown tomato, avid® (a.i. abamectin) was highly effective when applied as a drench at time of nematode inoculation. it strongly reduced root-galling and nematode reproduction, and prevented a reduct ... | 2011 | 22791920 |
foliar residue dynamics of azadirachtins following direct stem injection into white and green ash trees for control of emerald ash borer. | azadirachtins are natural insecticides derived from the neem tree. the emerald ash borer (eab) is an exotic invasive insect pest that infests various ash tree species and has the potential for significant economic, aesthetic and ecological impacts throughout north america. the initial translocation and foliar residue dynamics of azadirachtins were examined following direct injection into white and green ash trees growing in urban scenarios as a potential control for eab. | 2011 | 21567888 |
environmental safety to decomposer invertebrates of azadirachtin (neem) as a systemic insecticide in trees to control emerald ash borer. | the non-target effects of an azadirachtin-based systemic insecticide used for control of wood-boring insect pests in trees were assessed on litter-dwelling earthworms, leaf-shredding aquatic insects, and microbial communities in terrestrial and aquatic microcosms. the insecticide was injected into the trunks of ash trees at a rate of 0.2 gazadirachtin cm(-1) tree diameter in early summer. at the time of senescence, foliar concentrations in most (65%) leaves where at or below detection (<0.01 mg ... | 2011 | 21531021 |
thrombolytic potential of ocimum sanctum l., curcuma longa l., azadirachta indica l. and anacardium occidentale l. | atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed xin blood vessels. thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. herbal preparations have been used since ancient times for the treatment of several diseases. the aim of this study was to investigate whether herbal preparations possess thromb ... | 2011 | 24826011 |
status of carbohydrate, protein and lipid profile in the mosquito larvae treated with certain phytoextracts. | to investigate the impact of the most potent petroleum ether extract of artemisia annua (a. annua) and azadirachta indica (az. indica) on total carbohydrate, lipid and protein level of anopheles stephensi and culex quinquefasciatus larvae. | 2011 | 21771474 |
the neem [azadirachta indica a. juss (meliaceae)] oil reduction in the in vitro production of zearalenone by fusarium graminearum. | zearalenone, a mycotoxin produced by fungi of the genus fusarium, including f. graminearum, triggers reproduction disorders in certain animals and hyperestrogen syndromes in humans. current research investigates three concentrations of neem oil extract (0.1, 0.25 and 0.5%) in reducing the production of zearalenone. neem oil extract decreased zearalenone amount in the three concentrations but highest inhibition (59.05%) occurred at 0.1%. | 2011 | 24031683 |
indian culinary plants enhance glucose-induced insulin secretion and glucose consumption in ins-1 β-cells and 3t3-l1 adipocytes. | six indian plants, commonly used as culinary plants, herbs or spices (kikar; jamun; neem; harad; fenugreek; bitter gourd), were screened and compared for their antidiabetic potential in vitro. aqueous plant extracts were prepared and assessed for their effect on the insulin secretion activity of rat pancreatic ins-1 β-cells and glucose consumption in mouse 3t3-l1 adipocytes in order to study their specific mechanisms of action. the effect of the plant extract concentration (25-1000μg/ml) on insu ... | 2011 | 25212346 |
increasing the prosthodontic awareness of an aging indian rural population. | the aged are prone to biological, social, and psychological problems, especially those residing in the rural areas. the rural aging population in contrast to their urban counterparts is illiterate, poor, and ignorant; cumulative is the fact that the youth are leaving rural areas for money and better opportunity to urban areas. an educational and motivational program to increase prosthodontic awareness was therefore undertaken and it was studied whether this translated into an increased demand fo ... | 2011 | 22048572 |
role of chloroplastidial proteases in leaf senescence. | in this report the effect of hydrogen peroxide (h2o2) on peroxidase (pod) activity during leaf senescence was studied with and without phenylmethylsulfonyl fluoride (pmsf) pre-treatment in detached neem (azadirachta indica a. juss) leaf chloroplasts. increased pod activity was detected in natural and h2o2-promoted senescent leaf chloroplasts compared to untreated control mature green leaf chloroplasts. however, under h2o2 pod activity markedly increased at 1 day, and then significantly decreased ... | 2011 | 22024830 |
assessment of genetic diversity of 12 populations of azadirachta indica a. juss from three different locations in lagos state, nigeria using rapd markers. | the beneficial effects of plant materials typically result from the combination of secondary products present in the plant. neem tree is a common source of natural products for development of medicines against various diseases. | 2011 | 21913540 |
effect of marble dust on plants around vishwakarma industrial area (vkia) in jaipur, india. | the paper describes the effect of marble dust on plants in and around vishwakarma industrial area (vkia) jaipur, rajasthan (india). trees species growing in and around vkia area were selected and various morphological characteristics were studied such as leaf area dry weight ratio (ladwr), dust retaining capacity (drc) and chlorophyll content. in the study the effects of marble dust on selected tree species was observed. ladwr was recorded maximunm 217.90 cm2 g(-1) dry wt. in polyalthia longifol ... | 2011 | 21882657 |
standardization of some herbal antidiabetic drugs in polyherbal formulation. | ayurvedic formulations are used to treat a wide variety of diseases including diabetes mellitus standardization of herbal formulation is essential in order to assess the quality of drugs. the present paper reports standardization of eight herbal anti-diabetic drugs-momordica charantia (seeds), syzigium cumini (seeds), trigonella foenum (seeds), azadirachta indica (leaves), emblica offi cinalis (fruits), curcuma longa (rhizomes), gymnema sylvestre (leaves), pterocarpus marsupium (heart-wood) indi ... | 2011 | 21731396 |
is a combine therapy of aqueous extract of azadirachta indica leaf (neem leaf) and chloroquine sulphate toxic to the histology of the rabbit cerebellum? | herbal medication is commonly employed in treatment of diseases. aqueous extract of azadirachta indica leaf (a. indica) is commonly used in treatment of malaria by nigerians. most often, aqueous extract of a. indica leaf is taken in combination with chloroquine in order to cure malaria infection without knowledge of the side effect especially by the rural dwellers in nigeria. | 2011 | 23209976 |
artificial neural network and multiple regression model for nickel(ii) adsorption on powdered activated carbons. | nickel removal efficiency of powered activated carbons of coconut oilcake, neem oilcake and commercial carbon was investigated by using artificial neural network. the effective parameters for the removal of nickel (%r) by adsorption process, which included the ph, contact time (t), distinctiveness of activated carbon (cn), amount of activated carbon (cw) and initial concentration of nickel (co) were investigated. levenberg-marquardt (lm) back-propagation algorithm is used to train the network. t ... | 2011 | 23029923 |
scalable synthesis of aligned carbon nanotubes bundles using green natural precursor: neem oil. | practical application of aligned carbon nanotubes (acnts) would have to be determined by a matter of its economical and large-scale preparation. in this study, neem oil (also named margoaa oil, extracted from the seeds of the neem--azadirachta indica) was used as carbon source to fabricate the bundles of acnts. acnts have been synthesized by spray pyrolysis of neem oil and ferrocene mixture at 825°c. the major components of neem oil are hydrocarbon with less amount of oxygen, which provided the ... | 2011 | 21711585 |
increased production of azadirachtin from an improved method of androgenic cultures of a medicinal tree azadirachta indica a. juss. | present report is the first direct evidence of azadirachtin production in androgenic haploid cultures of azadirachta indica, a woody medicinal tree. anther cultures at early-late-uninucleate stage of microspores were established on ms medium with bap (5 μm), 2,4-d (1 μm) and naa (1 μm) containing 12% sucrose. the calli, induced, were further multiplied on 2,4-d and kinetin media. shoots, differentiated on bap (2.2 μm) + naa (0.05 μm) medium, were elongated on ms + bap (0.5 μm) and multiplied on ... | 2011 | 21701249 |
cytotoxic triterpenoids from azadirachta indica. | two new tirucallane triterpenoids, 24,25-epoxy-3 β-hydroxy-20-oxo-7-tirucallene (1) and 22,23;24,25-diepoxy-3 β-hydroxy-7-tirucallene (2), and a new tetranortriterpenoid, 4 α-hydroperoxy-6- o-acetylnimbandiol (3), along with eight known compounds, were isolated from the branches and leaves of azadirachta indica. their structures were elucidated through spectroscopic and chemical methods. the cytotoxic assay showed that the abundant constituent nimbolide (8) had obvious cytotoxic activities again ... | 2011 | 21674442 |
efficacy of selected pesticides against synanthropic mites under laboratory assay. | the efficacies of organophosphate pesticides, single-compound versus multicompound pyrethroid formulations and relatively novel unclassified insecticides/acaricides were compared to find the lowest dosage and highest efficacy for the control of dermatophagoides farina (hughes), d. pteronyssinus (trouessart) and tyrophagus putrescentiae (schrank). formulated active ingredients (ais) were diluted in water and applied onto filter paper in experimental chambers with ten unsexed adult mites in six re ... | 2011 | 21264998 |
effect of azadirachta indica (neem), sodium thiosulphate and calcium chloride on changes in nitrogen transformations and inhibition of nitrification in soil incubated under laboratory conditions. | a laboratory experiment was conducted to examine the effects of nitrification inhibitors (nis) neem seed-cake (azadirachta indica) (nsc), sodium thiosulphate (na₂s₂o₃) and calcium chloride (cacl₂) on changes in nh₄(+)⁻n, inhibition of nitrification and recovery of applied nitrogen (n) in soil. surface soil samples of 0-15 cm were collected from an arable field, amended with urea n (un) at the rate 200 mg n kg⁻¹, un+nsc, un+na₂s₂o₃ and un+cacl₂ and incubated at 22°c periodically over 50 d. soil w ... | 2011 | 21146192 |
an acidic phospholipase a(2) (rvva-pla(2)-i) purified from daboia russelli venom exerts its anticoagulant activity by enzymatic hydrolysis of plasma phospholipids and by non-enzymatic inhibition of factor xa in a phospholipids/ca(2+) independent manner. | a homodimeric acidic pla(2) (rvva-pla(2)-i) of 58.0 kda molecular weight purified from russell's viper (daboia russelli) venom demonstrated dose-dependent catalytic, strong anticoagulant and indirect hemolytic activities and inhibited blood coagulation cascade in both enzymatic and non-enzymatic mechanisms. in in vitro condition, rvva-pla(2)-i showed preferential hydrolysis of phosphatidylcholine with a k(m) and v(max) values of 0.65 mm and 28.9 μmol min(-1), respectively. biochemical study and ... | 2011 | 21356226 |
a comprehensive study on characterization of elite neem chemotypes through mycofloral, tissue-cultural, ecomorphological and molecular analyses using azadirachtin-a as a biomarker. | azadirachtin-a (aza-a), a tetranortriterpenoid, found in minuscule amounts in the neem seed-kernels, has proved to be a potent biopesticide. given the vast biodiversity of azadirachta indica (neem) in india, this study is an overview of four main aspects that corroborate with each other in identifying elite neem chemotypes based on their aza-a content. these biomarkers included mycofloral, tissue-cultural, ecomorphometrical and molecular analyses on accessions from five ecogeographically differe ... | 2011 | 23572995 |
neem leaf glycoprotein partially rectifies suppressed dendritic cell functions and associated t cell efficacy in patients with stage iiib cervical cancer. | myeloid-derived dendritic cells (dcs) generated from monocytes obtained from stage iiib cervical cancer (cacx iiib) patients show dysfunctional maturation; thus, antitumor t cell functions are dysregulated. in an objective to optimize these dysregulated immune functions, the present study is focused on the ability of neem leaf glycoprotein (nlgp), a nontoxic preparation of the neem leaf, to induce optimum maturation of dendritic cells from cacx iiib patients. in vitro nlgp treatment of immature ... | 2011 | 21307275 |
induction of apoptosis and inhibition of pi3k/akt pathway in pc-3 and lncap prostate cancer cells by ethanolic neem leaf extract. | the present study is aimed to delineate the effect of ethanolic neem leaf extract on pi3k/akt and apoptotic pathway in prostate cancer cell lines (pc-3 and lncap). | 2011 | 21277364 |
antidiabetic properties of azardiracta indica and bougainvillea spectabilis: in vivo studies in murine diabetes model. | diabetes mellitus is a metabolic syndrome characterized by an increase in the blood glucose level. treatment of diabetes is complicated due to multifactorial nature of the disease. azadirachta indica adr. juss and bougainvillea spectabilis are reported to have medicinal values including antidiabetic properties. in the present study using invivo diabetic murine model, a. indica and b. spectabilis chloroform, methanolic and aqueous extracts were investigated for the biochemical parameters importan ... | 2011 | 19389871 |
antidiabetic indian plants: a good source of potent amylase inhibitors. | diabetes is known as a multifactorial disease. the treatment of diabetes (type ii) is complicated due to the inherent patho-physiological factors related to this disease. one of the complications of diabetes is post-prandial hyperglycemia (pphg). glucosidase inhibitors, particularly α-amylase inhibitors are a class of compounds that helps in managing pphg. six ethno-botanically known plants having antidiabetic property namely, azadirachta indica adr. juss.; murraya koenigii (l.) sprengel; ocimum ... | 2011 | 18955350 |
to evaluate the antigingivitis and antipalque effect of an azadirachta indica (neem) mouthrinse on plaque induced gingivitis: a double-blind, randomized, controlled trial. | azadirachta indica (neem), a meliaceae family tree, has been used in india for several decades for the treatment of several diseases in medicine and dentistry. neem has been considered to have antiseptic activity, but still its use for the treatment of gingivitis and periodontitis is not very clear. hence, the purpose of the present study was to assess the efficacy of neem based mouth rinse regarding its antigingivitis effect. | 2011 | 22368367 |
comparison of the effectiveness of a commercially available herbal mouthrinse with chlorhexidine gluconate at the clinical and patient level. | the key to good oral health is hidden in nature. natural herbs like neem, tulsi, pudina, clove oil, ajwain, triphala and many more has been used since ages either as a whole single herb or as a combination against various oral health problems like bleeding gums, halitosis, mouth ulcers and preventing tooth decay. the aim of the study was to compare the efficacy of a commercially available herbal mouthrinse (herboral) with that of chlorhexidine gluconate which is considered to be a gold standard ... | 2011 | 22368358 |
organic matrix based slow release fertilizer enhances plant growth, nitrate assimilation and seed yield of indian mustard (brassica juncea l.). | field experiments were conducted to study the effect of organic matrix based slow release fertilizers (srfs) on plant growth, nitrate assimilation and seed yield of brassica juncea l. cv, pusa bold. the agro-waste materials like cow dung, clay soil, neem leaves and rice bran were mixed together in 2:2:1:1 ratio and used as organic matrix for the immobilization of chemical fertilizer nutrients with commercial grade saresh (acacia gum, 15% solution) as binder. different fertilizer treatments were ... | 2011 | 22319878 |
prevalence and pattern of use of indigenous medicines in diabetic patients attending a tertiary care centre. | the aim of the study was to see the pattern of use of indigenous medicines in diabetic patients and to find out its correlation with various demographic variables in patients of type 2 diabetes. a sample of 113 patients with diabetes (type 1 and type 2) was interviewed using a structured questionnaire by trained medical personnel about the intake of indigenous medicines. correlation of intake of indigenous medicines with various demographic variables was assessed using appropriate statistical te ... | 2011 | 22315837 |
purification of azadirachta indica seed cake and its impact on nutritional and antinutritional factors. | azadirachta indica juss. (family meliaceae) is a vital plant with multiple agricultural and medicinal utilities. the seed cake after oil extraction can be a good source of nutrition in animal feed. the limitation to its use is the presence of azadirachtin, salannin, and other bitter constituents. to make it palatable for use as a source of animal nutrition it was detoxified using 50 and 80% methanol and was analyzed for contents of azadirachtin, salannin, and nutritional contents such as total c ... | 2010 | 20218605 |
development of a new controlled pesticide delivery system based on neem leaf powder. | in order to minimize the agro-environmental pollution and health hazards caused by pesticides, in the present study, the neem leaf powder "(nlp)", a bio-pesticide, has been exploited to develop the pesticide delivery devices. the presence of neem in the formulations along with the pesticide may enhance the potential of these systems due to its inherent pesticidal activity. we have prepared the nlp and alginate based beads by using cacl(2) as crosslinker. to study the effect of composition of the ... | 2010 | 20042287 |
efficacy of some oils and chemical compounds on insignorthezia insignis (browne) (hemiptera: ortheziidae) infesting lantana camara in alexandria, egypt. | field and laboratory experiments were conducted in march, 2008 in el-nouzha garden, alexandria governorate. pre-and post treatment inspections of the insects were examined and recorded before and after (2,4,8, and 12 weeks). spraying was applied to evaluate the efficiency of the tested compounds, [mineral oils (kz oil and star oil); igrs (chlorfluazuron, lufenuron and pyriproxyfen); neem oil; emamectin benzoate and thiamethoxam]. percentages of reduction were calculated. the ensign scale insects ... | 2010 | 21539253 |
detection of a related difference in efficacy of azadirachtin treatments for the control of whiteflies on gerbera jamesonii by testing for interactions in generalised linear models. | within a project cluster, systemical effects of two neem treatments (neem azal u and neem pellet) on the number of trialeurodes vaporariorum (westw.) in gerbera jamesonii flori line maxi were investigated. in order to minimise adverse ecological effects of a product, a new plant protection product can be declared as superior to a reference if it shows the same or a higher effect at a lower dosage. | 2010 | 19924680 |
toothbrush contamination by candida spp. and efficacy of mouthrinse spray for their disinfection. | the aim of the study was to evaluate toothbrush contamination in vivo by candida spp. and the efficacy of periogard and neem sattiva, in spray, in the disinfection of these toothbrushes. this study was performed in three phases in which mouthrinses and sterile distilled water (control group) were sprayed six times on toothbrush bristles used by 61 university students. toothbrushes were then submitted to microbiological processing for the isolation and identification of candida species. fifty-nin ... | 2010 | 19774487 |
biological detection and analysis of toxicity of organophosphate- and azadirachtin-based insecticides in lathyrus sativus l. | in this study, attention was paid to investigate the effect of organophosphate insecticides, profenofos 40% ec, methyl parathion (metacid) 50% ec, and neem-based product nimbecidine 0.03% ec (from azadirachta indica) on somatic chromosomal behavior, level of leaf protein, and activity of antioxidant enzymes in lathyrus sativus l., the leguminous herb. the experiments on somatic chromosomes of root tip cells of l. sativus l. revealed that most common type of abnormalities were anaphase bridge, ch ... | 2010 | 19618265 |
azadirachtin poisoning: a case report. | the use of neem-based products is widespread in the indian subcontinent. neem-based pesticides obtained from neem kernels are considered natural and safe. the toxic effects of ingestion and overdose of this pesticide in adults have not been described in this literature. we report the case of a 35-year-old lady who had consumed azadirachtin in an attempt of deliberate self-harm. the patient had features of neurotoxicity because of azadirachtin requiring intensive medical care with mechanical vent ... | 2010 | 20932102 |
air pollution tolerance index (apti) of some tree species growing near rail roads of madurai, tamil nadu (india). | biological monitoring and assessment studies due to urban--rail road pollutants were carried out using air pollution tolerance index (apti) of plants. four plant (leaf) parameters--namely ascorbic acid, total chlorophyll, relative water content and leaf extract ph were combined together in a formulation signifying the apti of plants. apti was calculated for five different species such as azadirachta indica, delonix regia, ficus religiosa, pongamia pinnata and polyalthia longifolia growing in two ... | 2010 | 22312796 |
comparison of neem or oregano with thiram on organic matter decomposition of a sand loam soil amended with compost, and on soil biological activity. | oregano essential oil and neem have been reported to be effective against soil-borne pathogens and nematodes. the possibility of having an effect on soil properties was the aim of this investigation. moreover, thiram, a common widely used chemical pesticide, was used for comparison. | 2010 | 20355044 |
regenerative potential of aqueous extract of neem azadirachta indica on the stomach and ileum following ethanol-induced mucosa lesion in adult wistar rats. | the aim of this study was to examine whether neem azadirachta indica possesses regenerative potential on the stomach and ileum at 500 mg/kg dose given every 12 hours after mucosa lesion was brought by the administration of 1 ml of 50% ethanol for 21 consecutive days in adult wistar rats. | 2010 | 27956991 |
removal of free fatty acid in azadirachta indica (neem) seed oil using phosphoric acid modified mordenite for biodiesel production. | in this study free fatty acids present in azadirachta indica (neem) oil were esterified with our synthesized phosphoric acid modified catalyst. during the esterification, the acid value was reduced from 24.4 to 1.8 mg koh/g oil. synthesized catalyst was characterized by nh(3) tpd, xrd, sem, ftir and tga analysis. during phosphoric acid modification hydrophobic character and weak acid sites of the mordenite were increased, which lead to better esterification when compared to h-mordenite. a kineti ... | 2010 | 20346652 |
modification of cysteine 179 of ikappabalpha kinase by nimbolide leads to down-regulation of nf-kappab-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents. | reverse pharmacology, also called the "bedside to bench" approach, that deals with new uses for a well known molecular entity has been used extensively in cancer drug development to identify novel compounds and delineate their mechanisms of action. here, we show that nimbolide, a triterpenoid isolated from azadirachta indica, enhanced the apoptosis induced by inflammatory cytokines and chemotherapeutic agents in tumor cells. this limonoid abrogated the expression of proteins associated with cell ... | 2010 | 20829362 |
effect of pest controlling neem and mata-raton leaf extracts on greenhouse gas emissions from urea-amended soil cultivated with beans: a greenhouse experiment. | in a previous laboratory experiment, extracts of neem (azadirachta indica a. juss.) and gliricidia sepium jacquin, locally known as mata-raton, used to control pests on crops, inhibited emissions of co(2) from a urea-amended soil, but not nitrification and n(2)o emissions. we investigated if these extracts when applied to beans (phaseolus vulgaris l.) affected their development, soil characteristics and emissions of carbon dioxide (co(2)) and nitrous oxide (n(2)o) in a greenhouse environment. un ... | 2010 | 20692019 |
antiplasmodial triterpenoids from the fruits of neem, azadirachta indica. | eight known and two new triterpenoid derivatives, neemfruitins a (9) and b (10), have been isolated from the fruits of neem, azadirachta indica, a traditional antimalarial plant used by asian and african populations. in vitro antiplasmodial tests evidenced a significant activity of the known gedunin and azadirone and the new neemfruitin a and provided useful information about the structure-antimalarial activity relationships in the limonoid class. | 2010 | 20669933 |
acute and reproductive effects of align, an insecticide containing azadirachtin, on the grape berry moth, lobesia botrana. | azadirachtin, derived from the neem tree, azadirachta indica a. juss (sapindales: meliaceae), seems promising for use in integrated pest management programs to control a variety of pest species. a commercial formulation of azadirachtin, align, has been evaluated against different developmental stages of the european grape berry moth, lobesia botrana denis and schiffermüller (lepidoptera: tortricidae). when administered orally, align reduced the fecundity and fertility of adults treated with 1, 5 ... | 2010 | 20578954 |
mr imaging findings of neem oil poisoning. | 2010 | 20448012 | |
development of controlled release formulations of azadirachtin-a employing poly(ethylene glycol) based amphiphilic copolymers. | controlled release (cr) formulations of azadirachtin-a, a bioactive constituent derived from the seed of azadirachta indica a. juss (meliaceae), have been prepared using commercially available polyvinyl chloride, polyethylene glycol (peg) and laboratory synthesized poly ethylene glycol-based amphiphilic copolymers. copolymers of polyethylene glycol and various dimethyl esters, which self assemble into nano micellar aggregates in aqueous media, have been synthesized. the kinetics of azadirachtin- ... | 2010 | 20401782 |
role of honey (madhu) in the management of wounds (dushta vrana). | application of madhu (honey) is one among the shashthi upakrama (sixty treatment modalities) described by sushruta. clinical observation has shown its effectiveness in treatment of dushta vrana (chronic wounds). we report a case of dushta vrana on the anterior aspect of the right leg that was treated successfully with local application of madhu and neem (azadirachata indica) bark decoction. | 2010 | 21455457 |
toxic effects of neem cake extracts on aedes albopictus (skuse) larvae. | in order to investigate its insecticide potential, the neem cake methanol extract was first analyzed and then separated by different solvents. the high-performance liquid chromatography analysis showed that the neem cake methanol extract still contained relevant quantities of nortriterpenes. fractions of increasing polarity were obtained from the separation process: hexane fraction (hp), etoac fraction (ep), n-buoh fraction (bp), and aqueous fraction (wp). the activity of the fractions on aedes ... | 2010 | 20352448 |
mass attenuation coefficients of x-rays in different medicinal plants. | the mass attenuation coefficients of specific parts of several plants, (fruits, leaves, stem and seeds) often used as medicines in the indian herbal system, have been measured employing nai (ti)) detector. the electronic setup used is a nai (ti) detector, which is coupled to mca for analysis of the spectrum. a source of (241)am is used to get x-rays in the energy range 8-32kev from cu, rb, mo, ag and ba targets. in the present study, the measured mass attenuation coefficient of ocimum sanctum, c ... | 2010 | 19910203 |
sunlight decreased genotoxicity of azadirachtin on root tip cells of allium cepa and eucrosia bicolor. | utilization of neem plant (azadirachta indica a. juss) extract for pest control in agriculture has raised concerns over contamination by the residues to the environment. such residues, particularly azadirachtin (aza), may cause deleterious effect to non-target organisms. this investigation was conducted to find out if aza could be inactivated through exposures to sunlight. activity of aza was assessed as its ability to cause cytotoxic and genotoxic effects in the forms of nuclei abnormality and ... | 2010 | 20452021 |
nematicidal natural products from the aerial parts of buddleja crispa. | studies on the aerial parts of buddleja crispa yielded 13 known compounds, nonyl benzoate, hexyl p-hydroxy-cinnamate, ginipin, gardiol, 1-heptacosanol, steroidal galactoside (22 r)-stigmasta-7,9 (11)-dien-22 beta-ol-3beta-o-beta-d-galactopyranoside, 3-methoxy benzoic acid, beta-sitosterol and ursolic acid. besides this two iridoid galactosides buddlejosides a, buddlejosides b and a benzofuran-type sesquiterpene buddlejone have been isolated from the etoac fraction of b. crispa. together with the ... | 2010 | 20461624 |
nematicidal natural products from the aerial parts of rubus niveus. | studies on the aerial parts of rubus niveus yielded six known compounds, 3,5-dihydroxy benzoic acid c(7)h(6)o(4), (1), gallic acid c(7)h(6)o(5) (2), ethyl galactoside (3), oleanolic acid (4), beta-sitosterol (5) and 3-o-[beta-d-galactopyranosyl-(12)-d-glucopyranoside (6). besides this, a gallic acid derivative with methyl substitution was synthesised as tetramethyl gallate (3). together with this derivative, compounds 1, 2, the alcohol soluble, chloroform soluble and petroleum ether soluble extr ... | 2010 | 20306362 |
anti-plasmodial effects of azadirachta indica in experimental cerebral malaria: apoptosis of cerebellar purkinje cells of mice as a marker. | malaria is a major public health problem in the world, but treatment of malaria is becoming more difficult due to increasing drug resistance. therefore, the need for alternative drugs is acute. | 2010 | 22558559 |
biofabrication of anisotropic gold nanotriangles using extract of endophytic aspergillus clavatus as a dual functional reductant and stabilizer. | biosynthesis of metal and semiconductor nanoparticles using microorganisms has emerged as a more eco-friendly, simpler and reproducible alternative to the chemical synthesis, allowing the generation of rare forms such as nanotriangles and prisms. here, we report the endophytic fungus aspergillus clavatus, isolated from surface sterilized stem tissues of azadirachta indica a. juss., when incubated with an aqueous solution of chloroaurate ions produces a diverse mixture of intracellular gold nanop ... | 2010 | 27502640 |
new antitrypanosomal tetranotriterpenoids from azadirachta indica. | organic extracts of the leaves of azadirachta indica a. juss. yielded ten antitrypanosomal terpenoids. three of these (1-3), are novel and are derivatives of nimbolide and nimbin. they were extracted from chloroform fraction of methanol extract. these compounds were found to exhibit strong antitrypanosomal activities against trypanosoma brucei rhodesiense with mic values ranging of 6.9, 15.6 and 7.8 µg/ml respectively and were more active than cymerlarsan (a standard drug), which had an mic valu ... | 2010 | 21461147 |
antimicrobial activities of skincare preparations from plant extracts. | in this study, tithonia diversifolia helms. (a gray), aloe secundiflora (miller) and azadirachta indica (a. juss) plant extracts were used to make herbal soaps while thevetia peruviana (schum) seed oil was used to make a herbal lotion for skincare. the soaps were tested for the growth inhibition of escherichia coli, and candida albicans. the lotion was evaluated against staphylococcus aureus and e.coli. although tithonia diversifolia soap exhibited the highest inhibitory effect on the test bacte ... | 2010 | 21461148 |
effects of azadirachta indica on certain hematological parameters during benzo(a)pyrene induced murine forestomach tumorigenesis. | exposure to environmental toxicants/carcinogens, the process of carcinogenesis itself and cancer treatments lead to several secondary pathologies including hematological complications. considering versatile pharmacological potentials of azadirachta indica (a. indica), the present study was designed to evaluate its effects on certain hematological parameters in benzo(a)pyrene [b(a)p] induced murine forestomach tumorigenesis bioassay protocol. | 2010 | 21375139 |
an extract of neem leaves reduces anxiety without causing motor side effects in an experimental model. | anxiety modulation often requires pharmaceutical intervention, and though effective in the short-term, benzodiazepines may cause impaired motor function. as a potential alternative, anxiety-modulating effects of a neem leaf (azadirachta indica, a juss) extract were investigated using ethological analysis of rat behaviour on an elevated x maze and compared with diazepam treatment. sexually immature female sprague-dawley rats received 0.07 or 7 mg/kg neem leaf steroidal extract, a sham injection, ... | 2010 | 21291100 |
[selection of isolates of entomopathogenic fungi for controlling tuta absoluta (meyrick) (lepidoptera: gelechiidae) and their compatibility with insecticides used in tomato crop]. | the activity of metarhizium anisopliae and beauveria bassiana towards eggs and larvae of tuta absoluta (meyrick) was evaluated. our data showed that the isolates were pathogenic to both developmental stages tested and the eggs were more susceptible than the 1st instars. the isolates urpe-6 and urpe-19 of m. anisopliae were more pathogenic to eggs and larvae, respectively. the compatibility of these two isolates with the insecticides chlorfenapyr, spinosad, indoxacarb, abamectin, and neem were ev ... | 2010 | 21271067 |
water-extracted polysaccharides from azadirachta indica leaves: structural features, chemical modification and anti-bovine herpesvirus type 1 (bohv-1) activity. | in this study, we have analyzed the pectic arabinogalactan isolated from azadirachta indica and its chemically sulfated derivative. the native polysaccharide had an apparent molecular mass of 80 kda and is made up of (1→5)-/(1→3,5)-linked α-l-arabinosyl, (1→3)-/(1→6)-/(1→3,6)-linked β-d-galactosyl, and terminal-rhamnosyl and α-l-arabinosyl residues. these macromolecules showed activity against bovine herpesvirus type-1. their inhibitory concentration 50% values ranging from 31.12 to 105.25 μg/ml ... | 2010 | 20732349 |
the preparation of neem oil microemulsion (azadirachta indica) and the comparison of acaricidal time between neem oil microemulsion and other formulations in vitro. | the preparation of neem oil microemulsion and its acaricidal activity in vitro was developed in this study. in these systems, the mixture of tween-80 and the sodium dodecyl benzene sulfonate (sdbs) (4:1, by weight) was used as compound surfactant; the mixture of compound surfactant and hexyl alcohol (4:1, by weight) was used as emulsifier system; the mixture of neem oil, emulsifier system and water (1:3.5:5.5, by weight) was used as neem oil microemulsion. all the mixtures were stired in 800 rpm ... | 2010 | 20304561 |
alternative control of tetranychus evansi baker & pritchard (acari: tetranychidae) on tomato plants grown in greenhouses. | tetranychus evansi baker & pritchard is an important pest of solanaceous plants, including tomatoes. this mite is characterized by a high reproductive rate, which leads to high population growth in a short period of time causing important economic damage. control of t. evansi is mainly through synthetic acaricides. in searching for environmentally friendly control measures, we evaluated the efficiency of alternative products to control t. evansi on tomato plants under greenhouse conditions. the ... | 2010 | 20878004 |
identification of a sulfonoquinovosyldiacylglyceride from azadirachta indica and studies on its cytotoxic activity and dna binding properties. | chromatographic separation of the methanolic extract of the leaves of azadirachta indica led to the isolation of a sulfonoglycolipid characterized as a sulfonoquinovosyldiacylglyceride (sqdg), by extensive 2d nmr and mass spectral analysis. sqdg induces apoptosis in a dose dependent manner with ic(50) 8.3 μm against acute lymphoblastic leukemia (all) molt-4 cell lines. the compound showed significant dna binding properties as evidenced by the enhancement of melting temperature and perturbation o ... | 2010 | 20932749 |
primary tuberculosis of oral cavity: a rare entity revisited. | oral lesions of tuberculosis though uncommon, are seen both in the primary as well as the secondary stages of the disease. in secondary tuberculosis, the oral manifestations are accompanied by lesions in the lung, lymph nodes, or any other organ system of the body. this can be detected by the usual clinical history and systemic examination. primary oral tuberculosis may thus present as a diagnostic challenge to the clinician. amongst the oral lesions also, tongue is the usual site for tubercular ... | 2010 | 21063810 |
leishmania donovani: assessment of leishmanicidal effects of herbal extracts obtained from plants in the visceral leishmaniasis endemic area of bihar, india. | one obstacle faced in the effective control of visceral leishmaniasis (vl) is the limited number of available treatment options. furthermore, control efforts have been hindered further by the emergence of leishmania resistance to many of the available drugs. in this study, we investigated the anti-leishmanial properties of 30 medicinally important plants from the vl endemic area of bihar, india and compared them to two available anti-leishmanial drugs (sodium antimony gluconate and amphotericin ... | 2010 | 21070771 |
the effects of different plant extracts on nematodes. | the anthelminthic efficacy of some differently obtained extracts of several plants was tested in vivo in laboratory animals and in vitro. the extracts were obtained by ethanolic, methanolic, aqueous, or chloroform, respectively, acetonitrile polyethylenglycol (peg) and/or propylencarbonate (pc) elution at room temperature or at 37°c. the plants used were bulbs of onions, garlic, chives, coconut, birch tree, ananas, cistrose, banana, chicory, date palm fruit, fig, pumpkin, and neem tree seeds. th ... | 2010 | 21110041 |
[effects of tomato genotypes and aqueous extracts of melia azedarach leaves and azadirachta indica seeds on tuta absoluta (meyrick) (lepidoptera: gelechiidae)]. | insecticide plants are an important tool among the new alternatives for pest control in ipm systems because they reduce the use of synthetic insecticides, preserving human health and the environment. we investigated the effects of aqueous extracts of melia azedarach leaves and azadirachta indica seeds and three tomato genotypes, 'santa clara', 'ipa-5'--solanum lycopersicum (=lycopersicon esculentum mill), and la444-1--s. peruvianum (=l. peruvianum), on the development, reproduction and longevity ... | 2010 | 21120389 |
azadirachtin interacts with retinoic acid receptors and inhibits retinoic acid-mediated biological responses. | considering the role of retinoids in regulation of more than 500 genes involved in cell cycle and growth arrest, a detailed understanding of the mechanism and its regulation is useful for therapy. the extract of the medicinal plant neem (azadirachta indica) is used against several ailments especially for anti-inflammatory, anti-itching, spermicidal, anticancer, and insecticidal activities. in this report we prove the detailed mechanism on the regulation of retinoic acid-mediated cell signaling b ... | 2010 | 21127062 |
comparative repellent activities of some plant extracts against simulium damnosum complex. | abstract the root and leaf extracts of four plants, occimum gratissimum, azadirachta indica, pterocarpus santalinoides, and pistia hyptis, were studied for repellent activities against the adults of simulium damnosum sensu lato. the leaves and roots were extracted with 95% ethanol and the stocks were diluted with paraffin. the repellent activities of the extracts were investigated using human baits along the banks of river oyan and river ogun in southwestern nigeria. the results showed that the ... | 2010 | 21142952 |
traditional herbal medicine in far-west nepal: a pharmacological appraisal. | plant species have long been used as principal ingredients of traditional medicine in far-west nepal. the medicinal plants with ethnomedicinal values are currently being screened for their therapeutic potential but their data and information are inadequately compared and analyzed with the ayurveda and the phytochemical findings. | 2010 | 21144003 |
efficacy evaluation of a commercial neem cake for control of haematobia irritans on nelore cattle. | much attention has been given to the development of botanical insecticides to provide effective natural control of cattle ectoparasites without harming animals, consumers, and environment. this study evaluated the efficacy of a commercial neem cake in controlling haematobia irritans infestation on cattle. the study was conducted at the embrapa southeast cattle research center (cppse), in são carlos, sp, brazil, from april to july 2008. the neem cake mixed in mineral salt in a 2% concentration wa ... | 2010 | 21184697 |
effect of neem extract against the bacteria isolated from marine fish. | marine ornamental fishes are exceedingly valuable due to their high demand in domestic and international markets. there is a growing global interest to rear the fishes in captivity. but problem due to bacteria and fungi are the major hitch in captive condition. since, the use of antibiotics is banned, an attempt was made to ascertain in vitro assay of the neem leaves extract against the bacterial pathogens isolated from infected fishes. bacterial strains isolated from infected regions of the clo ... | 2010 | 21186711 |
effect of treatment with neem (azadirachta indica) compared with baycox drug on the caecum of chicken experimentally infected with eimeria tenella. | the study evaluated the therapeutic efficacy of neem herb in chicken experimentally infected with e. tenella compared to baycox as a reference anticoccidial drug. 120 broiler chicks were enrolled, randomly divided to 4 groups, (a, b, c & d) non-infected non-treated (naïve control), (b) infected with 10(4) e. tenella oocysts (infected control), (c) infected and treated with baycox (7 mg/kg b.w. for 2 days) and (d) infected and treated with neem leaves water extract (100 mg/kg b.w. for 9 days). ev ... | 2010 | 20503590 |
fecal glucocorticoids as indicators of metabolic stress in female sykes' monkeys (cercopithecus mitis albogularis). | because of their mediating role in the stress response and potential effects on fitness, glucocorticoid (gc) hormones are increasingly used to assess the physiological costs of environmental and behavioral variation among wild vertebrates. identifying the proximate causes of gc variation, however, is complicated by simultaneous exposure to multiple potentially stressful stimuli. here, we use data from a partially provisioned social group of sykes' monkeys to evaluate the effects of potential psy ... | 2010 | 20540944 |
light and scanning electron microscopic investigations on mitestop-treated poultry red mites. | recent studies of the neem seed product mitestop showed that it has a good acaricidal effect against all developmental stages of the poultry red mite, dermanyssus gallinae. in vitro tests proved an efficacy at direct contact, as well as by fumigant toxicity. light and scanning electron microscopic (sem) investigations showed no clear, morphologically visible signs of an effect caused by fumigant toxicity. direct contact with the neem product, however, seemed to be of great impact. chicken mites ... | 2010 | 20563823 |
selective effects of natural and synthetic insecticides on mortality of spodoptera frugiperda (lepidoptera: noctuidae) and its predator eriopis connexa (coleoptera: coccinellidae). | spodoptera frugiperda smith (lepidoptera: noctuidae) is a serious pest of corn in several american countries. it is mainly controlled with synthetic insecticides. the objectives of this study were to evaluate the effects of the natural products, neem oil and pyroligneous extract, and the synthetic insecticide, lufenuron, at 2.50 ml water (0.25%) on the mortality of 2-, 4- and 6-day-old caterpillars of s. frugiperda, and their selectivities against fourth instar larvae of eriopis connnexa germar ... | 2010 | 20603748 |
restoration of dysregulated cc chemokine signaling for monocyte/macrophage chemotaxis in head and neck squamous cell carcinoma patients by neem leaf glycoprotein maximizes tumor cell cytotoxicity. | previous studies have shown that the cc chemokine receptor ccr5 is downregulated on monocyte/macrophage (mo/mphi) surfaces in head and neck squamous cell carcinoma (hnscc) patients (stage iiib). ligands (rantes, mip-1alpha and mip-1beta) of this chemokine receptor were also secreted in lesser quantity from mo/mphi of hnscc patients in comparison with healthy individuals. in an aim to restore this dysregulated receptor-ligand signaling, we have used neem leaf glycoprotein (nlgp), a novel immunomo ... | 2010 | 20622890 |
anti-clastogenic activity of azadirachta indica against benzo(a)pyrene in murine forestomach tumorigenesis bioassay. | abstract: present study evaluated the anti-clastogenic efficacy of azadirchta indica (a. indica) against benzo(a)pyrene [b(a)p] in murine forestomach tumorigenesis bioassay protocol. female balb/c mice were divided into four groups (n = 8). each mouse from b(a)p and b(a)p + a. indica groups received intragastric instillations of b(a)p at a dose of 40 mg/kg b. w. in 0.2 ml olive oil twice a week, starting from 3rd week to the end of 6th week of the experiment. mice of control and a. indica groups ... | 2010 | 20635534 |
deoxygedunin, a natural product with potent neurotrophic activity in mice. | gedunin, a family of natural products from the indian neem tree, possess a variety of biological activities. here we report the discovery of deoxygedunin, which activates the mouse trkb receptor and its downstream signaling cascades. deoxygedunin is orally available and activates trkb in mouse brain in a bdnf-independent way. strikingly, it prevents the degeneration of vestibular ganglion in bdnf -/- pups. moreover, deoxygedunin robustly protects rat neurons from cell death in a trkb-dependent m ... | 2010 | 20644624 |
deleterious activity of natural products on postures of spodoptera frugiperda (lepidoptera: noctuidae) and diatraea saccharalis (lepidoptera: pyralidae). | the control of lepidoptera pests should be carried out before hatching of their caterpillars to avoid damage to the crops. the aim of this work was to assess the activity of neem (trade name: natuneem, producer: base fértil, chapadão do sul, brazil) and pyroligneous extracts (trade name: biopirol 7m, producer: biocarbo, itabirito, brazil) at 10 ml/l (1%) and 20 ml/l (2%) contents on egg masses of different ages of spodoptera frugiperda smith (lepidoptera: noctuidae) and of diatraea saccharalis f ... | 2010 | 20653245 |
azadirachta indica a. juss (neem) induced morphological changes on oocytes of rhipicephalus sanguineus (latreille, 1806) (acari: ixodidae) tick females. | many studies have been conducted with plants whose extracts have the potential to be used for pest control. one of these plants is azadirachta indica (neem), whose main active ingredient is azadirachtin, a compound shown to have acaricide and insecticide activity. rhipicephalus sanguineus (brown dog tick) is currently considered to be an "urban pest," because of its high levels of infestation and its ability to attack humans. in the present study partially and fully engorged r. sanguineus female ... | 2010 | 20685201 |
utilisation of priority traditional medicinal plants and local people's knowledge on their conservation status in arid lands of kenya (mwingi district). | mwingi district lies within the kenyan arid and semiarid lands (asals) in eastern province. although some ethnobotanical surveys have been undertaken in some arid and semiarid areas of kenya, limited studies have documented priority medicinal plants as well as local people's awareness of conservation needs of these plants. this study sought to establish the priority traditional medicinal plants used for human, livestock healthcare, and those used for protecting stored grains against pest infesta ... | 2010 | 20712897 |
management of corm-rot disease of gladiolus by plant extracts. | a pot experiment was conducted to evaluate the efficacy of aqueous extracts of six plant species, namely azadirachta indica a. juss. (neem), alstonia scholaris (l.) r. br., lawsonia alba lam., allium cepa l., a. sativum l. and zingiber officinale roscoe, and a systemic fungicide carbendazim 50% (w/w) wp, to manage the corm-rot disease of gladiolus (gladiolus grandiflorus l.) caused by a fungal pathogen fusarium oxysporum f.sp. gladioli (massey) snyd. & hans. fusarium inoculation showed 80% disea ... | 2010 | 19557652 |
the neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral oncogenesis. | limonoids from the neem tree (azadirachta indica) have attracted considerable research attention for their cytotoxicity against human cancer cell lines. however, the antiproliferative and apoptosis inducing effects of neem limonoids have not been tested in animal tumour models. the present study was therefore designed to evaluate the relative chemopreventive potential of the neem limonoids azadirachtin and nimbolide in the hamster buccal pouch (hbp) carcinogenesis model by analyzing the expressi ... | 2010 | 19458912 |
microbacterium azadirachtae sp. nov., a plant-growth-promoting actinobacterium isolated from the rhizoplane of neem seedlings. | microbacterium strain ai-s262(t) was isolated from the rhizoplane of neem seedlings in the botanical garden of tamilnadu agricultural university, coimbatore, india, and subjected to phenotypic, chemotaxonomic and genetic characterization. cells of this strain were gram-stain-positive, motile, non-spore-forming, short rods and formed light-yellow-pigmented colonies on nutrient agar. strain ai-s262(t) contained mk-12 and mk-13 as the main respiratory quinones, anteiso-c(15 : 0), anteiso-c(17 : 0) ... | 2010 | 19734284 |
laboratory and field evaluation of neem (azadirachta indica a. juss) and chinaberry (melia azedarach l.) oils as repellents against phlebotomus orientalis and p. bergeroti (diptera: psychodidae) in ethiopia. | the study evaluated the efficacy of neem (azadirachta indica a. juss.) and chinaberry (melia azedarach l.) seed oils as repellents against laboratory and field populations of some sandflies in ethiopia. in the laboratory, concentrations of 2% and 5% neem oil in coconut oil tested against phlebotomus orientalis (vector of visceral leishmaniasis) provided 96.28% (95% ci=95.60-96.97) protection up to a mean time of 7h and 20 min and 98.26% (95% ci=93.46-104. 07) protection up to 9h, respectively. s ... | 2010 | 19854142 |
in vivo anthelmintic activity of azadirachta indica a. juss seeds against gastrointestinal nematodes of sheep. | this paper describes the in vivo anthelmintic activity of azadirachta indica seeds to justify their use in south-asia by traditional animal healers. seeds of a. indica were administered as crude powder (cp), crude aqueous (cae) and crude methanolic extracts (cme) at the doses of 1 and 3g/kg of body weight to sheep naturally infected with mixed species of gastrointestinal nematodes. the study design also included untreated as well as treated controls. faecal egg count reduction and larval counts ... | 2010 | 19963323 |
neem leaf glycoprotein matures myeloid derived dendritic cells and optimizes anti-tumor t cell functions. | in an objective to find out an effective, nontoxic dendritic cell (dc) maturating agent for human use, cd14(+) monocytes were differentiated with gmcsf/il-4 and matured with neem leaf glycoprotein (nlgp). nlgp matured dcs (nlgp-dcs) show upregulated expression of cd83, cd80, cd86, cd40 and mhcs, in a comparable extent of control, lps. nlgp-dcs secrete high amount of il-12p70 with low il-10. nlgp upregulates the expression of crucial transcription factor, ikaros, indicating maturation towards dc1 ... | 2010 | 19969119 |
azadirachtin interacts with the tumor necrosis factor (tnf) binding domain of its receptors and inhibits tnf-induced biological responses. | the role of azadirachtin, an active component of a medicinal plant neem (azadirachta indica), on tnf-induced cell signaling in human cell lines was investigated. azadirachtin blocks tnf-induced activation of nuclear factor kappab (nf-kappab) and also expression of nf-kappab-dependent genes such as adhesion molecules and cyclooxygenase 2. azadirachtin inhibits the inhibitory subunit of nf-kappab (ikappab alpha) phosphorylation and thereby its degradation and rela (p65) nuclear translocation. it b ... | 2010 | 20018848 |
biosynthesis of antimicrobial silver nanoparticles by the endophytic fungus aspergillus clavatus. | to induce the biosynthesis of silver nanoparticles (agnps) using aspergillus clavatus and evaluate their antimicrobial potential. | 2010 | 20025462 |
in vitro antiviral activity of neem (azardirachta indica l.) bark extract against herpes simplex virus type-1 infection. | herpes simplex virus type 1 (hsv-1) causes significant health problems from periodical skin and corneal lesions to encephalitis. we report here that an aqueous extract preparation from the barks of neem plant azardirachta indica acts as a potent entry inhibitor against hsv-1 infection into natural target cells. the neem bark extract (nbe) significantly blocked hsv-1 entry into cells at concentrations ranging from 50 to 100 microg/ml. the blocking activity of nbe was observed when the extract was ... | 2010 | 20041417 |
toxicity and potential anti-trypanosomal activity of ethanolic extract of azadirachta indica (maliacea) stem bark: an in vivo and in vitro approach using trypanosoma brucei. | to determine the toxicity and anti-trypanosomal activity of the ethanolic extract of azadirachta indica (maliacea) stem bark, through in vivo and in vitro approach using trypanosoma brucei brucei. | 2010 | 20079420 |
phytotherapy of ulcerative dermatitis induced by aeromonas hydrophila infection in goldfish ( carassius auratus ). | goldfish ( carassius auratus ) weighing 13 +/- 2 g were administered intramuscularly a sublethal dose (1.8 x 10 3 cfu/ml) of aeromonas hydrophila to induce ulcerative dermatitis. on day 3 and day 6 after infection the fish were dip-treated (for 5 min/day) with a tri-herbal concoction of curcuma longa, ocimum sanctum and azadirachta indica (1%). the ld 50 value was recorded at a concentration of 2.3 x 10 4 between 30 and 36 days after infection. in the infected untreated group the cumulative mort ... | 2010 | 20159736 |
transmission blocking activity of a standardized neem (azadirachta indica) seed extract on the rodent malaria parasite plasmodium berghei in its vector anopheles stephensi. | the wide use of gametocytocidal artemisinin-based combination therapy (act) lead to a reduction of plasmodium falciparum transmission in several african endemic settings. an increased impact on malaria burden may be achieved through the development of improved transmission-blocking formulations, including molecules complementing the gametocytocidal effects of artemisinin derivatives and/or acting on plasmodium stages developing in the vector. azadirachtin, a limonoid (tetranortriterpenoid) abund ... | 2010 | 20196858 |
ethnomedicinal and ethnopharmaco-statistical studies of eastern rajasthan, india. | the study was conducted in eastern parts of rajasthan from march 2008 to february 2009 to identify the important species used; determine the relative importance of the species surveyed and calculate the informant consensus factor (icf) in relation to medicinal plant use. methodology or material and methods: a total of 844 villagers (486 men and 358 women) were interviewed using specimen display method and a forest walk with interviewee and a semi-structured questionnaire was used to elicit the k ... | 2010 | 20214972 |
isolation and identification of the antibacterial active compound from petroleum ether extract of neem oil. | from a petroleum ether extract of neem oil (azadirachta indica a. juss) the new tetrahydrofuranyl diester 1 was isolated as an anti-bacterial constituent. 1 showed significant activities against three standard bacterial strains, including staphylococcus aureus atcc 25923, escherichia coli atcc 25922 and salmonella enteritidis cmcc (b) 50041. | 2010 | 20362038 |
[action of extract and oil neem in the control of rhipicephalus (boophilus) microplus (canestrini, 1887) (acari: ixodidae) in laboratory]. | organic plant extracts and emulsified oil of azadirachta indica a. juss (meliaceae) (neem) were studied to evaluate its effects in control of engorged females of rhipicephalus (boophilus) microplus (canestrini, 1887) in the laboratory. hexane and alcoholic organic extracts, 2% (weight/volume) were used in tests of immersion for 5 minutes, prepared with seeds, solubilized in dimethylsulfoxide (dmso) to 1%. the experiment was entirely randomized, consisting of 6 treatments and 5 replicates, each r ... | 2010 | 20385059 |
heavy metal bioaccumulation in selected medicinal plants collected from khetri copper mines and comparison with those collected from fertile soil in haridwar, india. | heavy metal distribution in medicinal plants is gaining importance not only as an alternative medicine, but also for possible concern due to effects of metal toxicity. the present study has been focused on emphasizing the heavy metal status and bioaccumulation factors of v, mn, fe, co, cu, zn, se (essential metals) and cr, ni, cd, as and pb (potentially toxic metals) in medicinal plants grown under two different environmental conditions e.g., near to khetri copper mine and those in fertile soils ... | 2010 | 20390948 |
in vitro and field studies on the contact and fumigant toxicity of a neem-product (mite-stop) against the developmental stages of the poultry red mite dermanyssus gallinae. | the acaricidal activity of the neem product mitestop was investigated for its potential use as a botanical acaricide for the control of the poultry red mite dermanyssus gallinae. this neem product is a special formulation of an extract of the seeds of the neem tree azadirachta indica a. juss. the efficacy was tested under laboratory conditions as well as in poultry houses. four different methods of application were used in a filter paper bioassay to evaluate contact and vapour phase toxicity tes ... | 2010 | 20424858 |
assessment of antioxidant capacity and cytotoxicity of selected malaysian plants. | thirteen malaysian plants; artocarpus champeden, azadirachta indica, fragaria x ananassa, garcinia mangostana, lawsonia inermis, mangifera indica, nephelium lappaceum, nephelium mutobile, peltophorum pterocarpum, psidium guajava and syzygium aqueum, selected for their use in traditional medicine, were subjected to a variety of assays. antioxidant capability, total phenolic content, elemental composition, as well as it cytotoxity to several cell lines of the aqueous and ethanolic extracts from di ... | 2010 | 20428033 |