Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| dengue virus reduces agpat1 expression to alter phospholipids and enhance infection in aedes aegypti. | more than half of the world population is at risk of dengue virus (denv) infection because of the global distribution of its mosquito vectors. denv is an envelope virus that relies on host lipid membranes for its life-cycle. here, we characterized how denv hijacks the mosquito lipidome to identify targets for novel transmission-blocking interventions. to describe metabolic changes throughout the mosquito denv cycle, we deployed a liquid chromatography-high resolution mass spectrometry (lc-hrms) ... | 2019 | 31815960 |
| genetic diversity of laboratory strains and implications for research: the case of aedes aegypti. | the yellow fever mosquito (aedes aegypti), is the primary vector of dengue, zika, and chikungunya fever, among other arboviral diseases. it is also a popular laboratory model in vector biology due to its ease of rearing and manipulation in the lab. established laboratory strains have been used worldwide in thousands of studies for decades. laboratory evolution of reference strains and contamination among strains are potential severe problems that could dramatically change experimental outcomes a ... | 2019 | 31815934 |
| glopid-r report on chikungunya, o'nyong-nyong and mayaro virus, part 5: entomological aspects. | the glopid-r (global research collaboration for infectious disease preparedness) chikungunya (chikv), o'nyong-nyong (onnv) and mayaro virus (mayv) working group has been established to investigate natural history, epidemiology and clinical aspects of infection by these viruses. here, we present a report dedicated to entomological aspects of chikv, onnv and mayv. recent global expansion of chikungunya virus has been possible because chikv established a transmission cycle in urban settings using a ... | 2019 | 31812638 |
| cryo-electron microscopy reveals that sperm modification coincides with female fertility in the mosquito aedes aegypti. | manipulating mosquito reproduction is a promising approach to reducing mosquito populations and the burden of diseases they carry. a thorough understanding of reproductive processes is necessary to develop such strategies, but little is known about how sperm are processed and prepared for fertilization within female mosquitoes. by employing cryo-electron microscopy for the first time to study sperm of the mosquito aedes aegypti, we reveal that sperm shed their entire outer coat, the glycocalyx, ... | 2019 | 31811199 |
| assessment of aedes aegypti (diptera: culicidae) males flight ability for sit application: effect of device design, duration of test, and male age. | the sterile insect technique (sit) is a pest control method where large numbers of sterile males are released to induce sterility in wild populations. since a successful sit application depends on the released sterile males being competitive with wild males, standard quality control tests are a necessary component of any sit program. flight ability (ability to fly out from a device) is a reliable indicator of insect quality. based on previous studies, we developed four new tubular devices constr ... | 2019 | 31808821 |
| malaria and dengue mosquito vectors from lao pdr show a lack of the rdl mutant allele responsible for cyclodiene insecticide resistance. | the gamma-aminobutyric acid (gaba) receptor, rdl, plays important roles in neuronal signaling and is the target of highly effective insecticides. a mutation in rdl, commonly a296s, underlies resistance to several insecticides such as cyclodienes. even though the use of cyclodienes has been banned, the occurrence of mutations substituting a296 is notably high in mosquitoes from several countries. here, we report a survey investigating the prevalence of the rdl mutant allele in mosquitoes from lao ... | 2019 | 31807752 |
| the consequences of brugia malayi infection on the flight and energy resources of aedes aegypti mosquitoes. | evidence from experimental infection studies has shown that infected mosquitoes exhibit altered host-seeking behaviours, with suppression and activation of behaviours dependent on the parasite's development stage. the mechanisms are poorly characterised; however, infections can impact mosquito energy reserves, thereby influencing key life-history traits and behaviours. in addition, filarial infection is likely detrimental to flight due to damage caused by developing worms. this study aimed to ev ... | 2019 | 31804546 |
| finding the sweet spot: what levels of larval mortality lead to compensation or overcompensation in adult production? | extrinsic mortality impinging on negatively density-dependent populations can result in no change in the number of survivors (compensation) or an increase (overcompensation) by releasing the population from density-dependent effects on survivorship. the relationship between the level of extrinsic mortality (i.e., percentage of mortality) and the level and likelihood of overcompensation is theoretically important, but rarely investigated. we tested the hypothesis that overcompensation occurs belo ... | 2019 | 31803516 |
| diterpenes and their derivatives as promising agents against dengue virus and dengue vectors: a literature-based review. | dengue, a mosquito-borne viral disease, causes about 100 million cases of infection annually. it is a major public concern, and if left untreated or improperly diagnosed, may cause serious health problems or even death. historically, dengue has not considered priorities for pharmaceutical companies made the available treatment options. therefore, medicinal scientists are revealing new insights and enabling novel interventions and approaches to dengue prevention and control. diterpenes, a class o ... | 2019 | 31802573 |
| [river boats as a means of expansion of aedes aegypti towards border zones of the peruvian amazon]. | to assess the entomological risk of aedes aegypti in boats traversing border river routes in loreto. | 2019 | 31800930 |
| investigating male aedes aegypti (diptera: culicidae) attraction to different oviposition containers using various configurations of the sound gravid aedes trap. | aedes aegypti (linnaeus), the primary vectors of the arboviruses dengue virus and zika virus, continue to expand their global distributions. in efforts to better control such species, several mosquito control programs are investigating the efficacy of rearing and releasing millions of altered male aedes throughout landscapes to reduce populations and disease transmission risk. unfortunately, little is known about ae. aegypti, especially male, dispersal behaviors within urban habitats. we deploye ... | 2019 | 31799614 |
| drug repurposing of bromodomain inhibitors as potential novel therapeutic leads for lymphatic filariasis guided by multispecies transcriptomics. | to better understand the transcriptomic interplay of organisms associated with lymphatic filariasis, we conducted multispecies transcriptome sequencing (rna-seq) on the filarial nematode brugia malayi, its wolbachia endosymbiont wbm, and its laboratory vector aedes aegypti across the entire b. malayi life cycle. in wbm, transcription of the noncoding 6s rna suggests that it may be a regulator of bacterial cell growth, as its transcript levels correlate with bacterial replication rates. for a. ae ... | 2019 | 31796568 |
| cdte-gsh as luminescent biomarker for labeling the larvicidal action of wsmol lectin in aedes aegypti larvae. | mosquito-borne arboviruses compromise human health worldwide. due to resistance to chemical insecticides, natural compounds have been studied to combat mosquitoes. previous works have demonstrated a larvicidal activity of the water-soluble moringa oleifera lectin (wsmol) against aedes aegypti, suggesting a mechanism of action based on the interaction between lectin and chitin present in the larvae's peritrophic matrix. in this work, it was investigated the wsmol activity against aedes aegypti la ... | 2019 | 31796242 |
| genome sequences of chikungunya virus isolates from an outbreak in southwest bangkok in 2018. | an outbreak of chikungunya virus (chikv) infection occurred in southwest bangkok during the 2018 rainy season. the envelope glycoprotein e1 gene sequence of the infecting strain belonged to an east/central/south african lineage with alanine at residue 226. mutations in the predicted e1 (k211e) and e2 (v264a) proteins of chikv were identified in chikv-infected patients and in an aedes aegypti mosquito. analysis of the complete genome sequences showed marked differences from the strains causing pr ... | 2019 | 31834526 |
| distribution of insecticide resistance and mechanisms involved in the arbovirus vector aedes aegypti in laos and implication for vector control. | the yellow fever mosquito aedes aegypti is the major vector of dengue, yellow fever, zika, and chikungunya viruses. worldwide vector control is largely based on insecticide treatments but, unfortunately, vector control programs are facing operational challenges due to mosquitoes becoming resistant to commonly used insecticides. in southeast asia, resistance of ae. aegypti to chemical insecticides has been documented in several countries but no data regarding insecticide resistance has been repor ... | 2019 | 31830027 |
| effects of larval diets and temperature regimes on life history traits, energy reserves and temperature tolerance of male aedes aegypti (diptera: culicidae): optimizing rearing techniques for the sterile insect programmes. | producing high quality sterile males is vital in aedes aegypti rear-and-release birth control strategies. larval diets, rearing temperatures, and their interactions determine the accumulation rates of essential nutrients in larvae, but these factors have been understudied in relation to mass-rearing techniques for producing eminent males. | 2019 | 31823817 |
| social capital is associated with lower mosquito vector indices: secondary analysis from a cluster randomised controlled trial of community mobilisation for dengue prevention in mexico. | control of the aedes aegypti mosquito is central to reducing the risk of dengue, zika, chikungunya, and yellow fever. randomised controlled trials, including the camino verde trial in mexico and nicaragua, demonstrate the convincing impact of community mobilisation interventions on vector indices. these interventions might work through building social capital but little is known about the relationship between social capital and vector indices. | 2019 | 31823786 |
| zika virus: a possible emerging threat for bangladesh! | zika virus, a member of flaviviridae is the etiology of zika or zika fever or zika virus (zikv) disease characterized by mild symptoms similar to very mild form of dengue or chikungunya. the virus transmits through aedes mosquitoes, particularly by aedes aegypti. the most dangerous effect of zikv infection is the ability of the virus to cause microcephaly and congenital malformation to the newborn baby if the mother is infected. the neurological disorders including guillain-barré syndrome might ... | 2019 | 31819889 |
| successive blood meals enhance virus dissemination within mosquitoes and increase transmission potential. | the recent zika virus (zikv) and chikungunya virus epidemics highlight the explosive nature of arthropod-borne viruses (arboviruses) transmitted by aedes spp. mosquitoes1,2. vector competence and the extrinsic incubation period (eip) are two key entomological parameters used to assess the public health risk posed by arboviruses3. these are typically measured empirically by offering mosquitoes an infectious blood meal and temporally sampling mosquitoes to determine the infection and transmission ... | 2019 | 31819213 |
| natural infection of aedes aegypti by chikungunya and dengue type 2 virus in a transition area of north-northeast brazil. | dengue fever, chikungunya, and zika are diseases caused by viruses transmitted by aedes aegypti and aedes albopictus. in brazil, the number of human infections is high, but few studies are performed in mosquito vectors. this study aimed to investigate the presence of zika, dengue and chikungunya viruses in ae. aegypti and ae. albopictus from the municipalities of alto alegre, caxias, codó, and são mateus do maranhão, located in the state of maranhão, northeast brazil. the mosquitoes were collect ... | 2019 | 31817553 |
| age- and sex-related abc transporter expression in pyrethroid-susceptible and -resistant aedes aegypti. | resistance mechanisms to synthetic insecticides often include point mutations and increased expression of genes encoding detoxification enzymes. since pyrethroids are the main adulticides used against aedes aegypti, which vectors pathogens such as zika virus, understanding resistance to this insecticide class is of significant relevance. we focused on adenosine triphosphate (atp)-binding cassette (abc) transporters in the pyrethroid-resistant puerto rico (pr) strain of ae. aegypti. we investigat ... | 2019 | 31862982 |
| leptolegnia chapmanii como alternativa biológica para el control de aedes aegypti | leptolegnia chapmanii is a facultative pathogen of many species of mosquitoes, among which species of the genus aedes, culex and anopheles stand out for their medical and sanitary importance. the potential of l. chapmanii as an alternative to control lies in its virulence, pathogenicity and specificity against the larval stages of mosquitoes, and because of its harmlessness to non-target species such as fish and amphibians, among others. the natural presence of l. chapmanii had been reported in ... | 2019 | 31860189 |
| the first characterization of a cystatin and a cathepsin l-like peptidase from aedes aegypti and their possible role in denv infection by the modulation of apoptosis. | recently, a salivary gland transcriptome study demonstrated that the transcripts of a putative cystatin gene (seqid aael013287; aacystatins) from aedes aegypti were increased in denv2-infected mosquitoes and that silencing of the aacystatin gene resulted in an increase in denv titres. in this work, aacystatin was biochemically characterized; the purified recombinant inhibitor was able to inhibit typical cysteine proteases with a ki in the nm range. pulldown assays using aag2 cell extracts identi ... | 2019 | 31857170 |
| insecticide resistance in culex quinquefasciatus say, 1823 in brazil: a review. | culex quinquefasciatus is a successful invasive species broadly distributed in subtropical regions, including brazil. it is an extremely annoying mosquito due to its nocturnal biting behavior, in high-density populations and it is a potential bridge between sylvatic arbovirus from birds to man in urban territories. herein, we present a review concerning the methods of chemical control employed against cx. quinquefasciatus in brazil since the 1950's and insecticide resistance data registered in t ... | 2019 | 31852489 |
| deducing the role of virus genome-derived piwi-associated rnas in the mosquito-arbovirus arms race. | the p-element-induced wimpy testis (piwi)-associated rna (pirna) pathway is known for its role in the protection of genome integrity in the germline of drosophila melanogaster by silencing transposable elements. the pirnas that target transposons originate from pirna clusters in transposon-rich regions of the drosophila genome and are processed by three piwi family proteins. in aedes aegypti and aedes albopictus mosquitoes, which are two of the most important vectors of arthropod-borne viruses ( ... | 2019 | 31850054 |
| mechanisms of transport of h+, na+ and k+, across the distal gastric caecum of larval aedes aegypti. | measured changes in ion fluxes, transepithelial potential (tep) and basolateral membrane potential (vb) in response to ion transporter inhibitors were used to assess the mechanisms of transport of h+, na+ and k+, across the distal gastric caecum of larval aedes aegypti, a vector of yellow fever. preparations were stimulated with 5-hydroxytryptamine (5-ht, 10-6 m) in order to maintain stable rates of h+, na+, and k+ transport across the distal caecum. transepithelial potential (tep), basolateral ... | 2019 | 31846613 |
| effect of wolbachia walbb on a positive-sense rna negev-like virus: a novel virus persistently infecting aedes albopictus mosquitoes and cells. | the aedes aegypti mosquito is the primary vector of several medically important arboviruses. the endosymbiotic bacterium, wolbachia pipientis, has emerged as a means of blocking transmission of arboviruses such as dengue and zika viruses. one wolbachia strain that has shown potential in field trials is walbb, a naturally occurring wolbachia strain of the asian tiger mosquito aedes albopictus. when transinfected into ae. aegypti, walbb exhibits strong virus inhibition. in addition to modulating a ... | 2019 | 31846415 |
| antidengue potential of leaf extracts of pavetta tomentosa and tarenna asiatica (rubiaceae) against dengue virus and its vector aedes aegypti (diptera: culicidae). | the aim of the present study was to screen the anti-dengue potential of crude leaf extracts of two plants from pavetta tomentosa and tarenna asiatica. for larvicidal assay, the acetone extract of both plants showed maximum effects, with the least lc50 and lc90 values (p. tomentosa (5.968 and 7.493 μg/ml) and t. asiatica (1.288 and 1.992 μg/ml)) and the same extract of both plants exhibited better pupicidal potency. the adulticidal activity of both plants (0-60 min interval periods) recorded best ... | 2019 | 31844692 |
| author correction: cartography of odor chemicals in the dengue vector mosquito (aedes aegypti l., diptera/culicidae). | an amendment to this paper has been published and can be accessed via a link at the top of the paper. | 2019 | 31844083 |
| nano-emulsification enhances the larvicidal potential of the essential oil of siparuna guianensis (laurales: siparunaceae) against aedes (stegomyia) aegypti (diptera: culicidae). | siparuna guianensis (laurales: siparunaceae) has a terpene-rich essential oil with great potential for larvicides. the poor water miscibility of their compounds makes nano-emulsions of great interest for novel bioactive systems, including for control of aedes aegypti (diptera: culicidae). this species is adapted to urban environments with important role in the epidemiology of some arboviruses such as dengue, chikungunya fever, zika, and urban yellow fever. the aim of the present study was to eva ... | 2019 | 31840745 |
| could land cover influence aedes aegypti mosquito populations? | aedes aegypti is mainly found in urban environments, where human activity guarantees the permanent availability of potential larval habitats. the present study aimed to test for a possible association between ae. aegypti infestation and land cover classes. from 23 february to 22 may 2015, immature mosquitoes (except eggs) were sampled in artificial containers identified in dwellings in córdoba city, argentina. the proportion of each land cover class was determined by spot-5 (satellites pour 1'ob ... | 2019 | 31840284 |
| co-occurrence of v1016i and f1534c mutations in the voltage-gated sodium channel and resistance to pyrethroids in aedes aegypti (l.) from the colombian caribbean region. | knockdown resistance is conferred primarily by non-synonymous mutations that reduce pyrethroids binding to voltage-gated sodium channels. in 2014, kdr mutation v1016i in aedes aegypti populations resistant to pyrethroids was reported for the first time in colombiα, in 2016 another kdr mutation, f1534c, and in 2018 the mutation v419l. nine populations of a. aegypti, previously characterized as being resistant to λ-cyhalothrin, deltamethrin, cyfluthrin and permethrin, were used for this study. gen ... | 2019 | 30520256 |
| volatile composition and biological activities of the leaf essential oil from zanthoxylum limoncello grown in oaxaca, méxico. | zanthoxylum limoncello is a native plant from southern mexico which is used as a timber source, condiment and as a traditional medicine. herein, we report on the volatile content of the leaf essential oil and its biological activities. the annual essential oils (2015-2018) contained volatile organic compounds which exhibited a moderate growth inhibitory activity against h. pylori atcc 53504 (mic 121.4-139.7 μg ml-1 ), 26695 (mic 85.5-94.9 μg ml-1 ) and j99 (mic 94.7-110.4 μg ml-1 ). these hydrod ... | 2019 | 30512233 |
| coinfection of chikungunya and dengue viruses: a serological study from north western region of punjab, india. | dengue and chikungunya (chik) infections appear to be increasing in all parts of india. aedes aegypti mosquitoes are common vectors for dengue virus (denv) and chik virus (chikv). in areas where both viruses cocirculate, they can be transmitted together. there are very few studies discussing the dengue-chik coinfection from punjab region of india. the present study was undertaken to study the clinical features of dengue-chik coinfection and compare with monoinfection. | 2019 | 30498319 |
| autocidal gravid ovitrap incorporation with attractants for control of gravid and host-seeking aedes aegypti (diptera: culicidae). | aedes aegypti linnaeus (diptera: culicidae) is a primary vector of multiple arboviruses including zika, dengue, chikungunya, and yellow fever. after incorporating bg lure or bg lure + octenol, the cdc's autocidal gravid ovitrap (ago) was more effective at collecting and controlling host-seeking female ae. aegypti than gravid female mosquitoes. the addition of octenol to the ago did not increase the number of female mosquitoes captured by the ago, compared with the ago alone. the ago baited with ... | 2019 | 30462293 |
| monitoring insecticide resistance profiles of aedes aegypti (diptera: culicidae) in the sunda islands of indonesia based on diagnostic doses of larvicides. | this study was conducted to monitor the susceptibility status of aedes aegypti (linnaeus) larvae in the sunda islands of indonesia against various organophosphates and organochlorines. larval bioassay was performed in accordance with the world health organization standard protocol. field-collected and reference strains of ae. aegypti larvae were tested against diagnostic doses of eight larvicides belonging to organophosphates and organochlorines, namely bromophos (0.050 mg/liter), chlopyrifos (0 ... | 2019 | 30462258 |
| past, present and future of aedes aegypti in its south american southern distribution fringe: what do temperature and population tell us? | aedes aegypti (diptera: culicidae) (linnaeus) is currently the major threat among arbovirus vectors in the americas. we examined its past, present, and future distribution patterns in the south american fringe in association with environmental and demographic variables at two spatial scales. we updated the database of the occurrence of ae. aegypti per locality and modelled by glmm the past occurrence (until 2000) and its expansion (2001-2017) as a function of air temperature, precipitation, alti ... | 2019 | 30458122 |
| water channel activity of putative aquaporin-6 present in aedes aegypti. | aquaporins (aqps) are integral membrane channels that facilitate the bidirectional transport of water and sometimes other small solutes across biological membranes. aqps are important in mediating environmental adaptations in mosquitoes and are considered as a novel target for the development of effective insecticides against mosquitoes. here, we expressed aedes aegypti aqp6 ( aaaqp6) in human embryonic kidney (hek) 293 cells and analyzed the water permeability by a conventional swelling assay, ... | 2019 | 30456765 |
| going viral 2019: zika, chikungunya, and dengue. | chikungunya and zika virus infections are emerging diseases in the americas, and dengue continues to be the most prevalent arthropod-borne virus in the world. these arbovirus diseases may spread by endemic transmission or as travel-related infections and have rapidly expanded their geographic distribution secondary to vector spread. all 3 share a similar clinical picture that includes a maculopapular rash. zika is characterized by pruritic rash, low-grade fever, and arthralgia. congenital nervou ... | 2019 | 30466692 |
| aedes aegypti vector competence studies: a review. | aedes aegypti is the primary transmitter of the four viruses that have had the greatest impact on human health, the viruses causing yellow fever, dengue fever, chikungunya, and zika fever. because this mosquito is easy to rear in the laboratory and these viruses grow in laboratory tissue culture cells, many studies have been performed testing the relative competence of different populations of the mosquito to transmit many different strains of viruses. we review here this large literature includ ... | 2019 | 30465912 |
| saccharomyces cerevisiae (baker's yeast) as an interfering rna expression and delivery system. | the broad application of rna interference for disease prevention is dependent upon the production of dsrna in an economically feasible, scalable, and sustainable fashion, as well as the identification of safe and effective methods for rna delivery. current research has sparked interest in the use of saccharomyces cerevisiae for these applications. this review examines the potential for commercial development of yeast interfering rna expression and delivery systems. s. cerevisiae is a genetic mod ... | 2019 | 30474529 |
| ecotoxicity response of chlorpyrifos in aedes aegypti larvae and lactuca sativa seeds after uv/h2o2 and uvc oxidation. | chlorpyrifos (cp) is an organophosphate pesticide widely used in agriculture known to cause neurological and immunological effects in addition to interfering in the reproduction and development of organisms. in this study, cp degradation by uv/h2o2 process and uvc radiation was investigated, and the ecotoxicity and phytotoxicity was evaluated using bioassays of aedes aegypti larvae and lactuca sativa seeds. cp degradation was monitored by hplc-dad, and kinetic parameters were calculated for all ... | 2019 | 30471582 |
| bioassay and molecular study for detection of insecticide resistance dengue causing mosquito vectors. | nowadays, dengue infection creates a major problem across the country. the vector species carrying dengue infection has progressively started to developed resistance against most of the currently used insecticides. hence, a study was carried out in dengue-endemic areas of assam and arunachal pradesh to find the current situation of insecticide susceptibility status of dengue vectors. based on the previous history of dengue incidence, aedes mosquitoes were collected from dibrugarh, kamrup, sivasa ... | 2019 | 30429402 |
| isolation and growth inhibition potential of entomopathogenic nematodes against three public health important mosquito vectors. | the prevalence of mosquito vector borne diseases and the resistance of mosquitoes to conventional pesticides have been of important public concern to the mosquito endemic countries. present study was conducted to identify the native bio-larvicidal potential of the entomopathogenic nematodes; steinernema siamkayai (kpr-4) heterohabditis indica (kpr-8), steinernema glaseri and steinernema abbasi. the isolated nematodes were subsequently cultured and evaluated their larvicidal potential against the ... | 2019 | 30414843 |
| preparation and use of a yeast shrna delivery system for gene silencing in mosquito larvae. | the mosquito genome projects facilitated research in new facets of mosquito biology, including functional genetic studies in the dengue and zika virus vector aedes aegypti and the primary african malaria vector anopheles gambiae. rna interference (rnai) has facilitated gene silencing experiments in both of these disease vector mosquito species and could one day be applied as a new method of vector control. here, we describe a procedure for the genetic engineering of saccharomyces cerevisiae (bak ... | 2019 | 30414120 |
| a statewide survey of container aedes mosquitoes (diptera: culicidae) in north carolina, 2016: a multiagency surveillance response to zika using ovitraps. | native and invasive container-inhabiting aedes mosquitoes (diptera: culicidae) play important roles in the transmission of endemic and traveler-introduced arboviruses in the united states. in response to the emergence of zika virus into the americas, we surveyed the distribution of container aedes spp. of public health importance within north carolina during 2016 using ovitraps. a seasonal survey was conducted in 18 counties from the mountains to the coast to identify species incriminated in the ... | 2019 | 30380070 |
| inhibition of sodium-hydrogen antiport by antibodies to nha1 in brush border membrane vesicles from whole aedes aegypti larvae. | the present research report describes na+/h+ antiport by brush border membrane vesicles isolated from whole larvae of aedes aegypti (aebbmvw). our hypothesis is that acid quenching of acridine orange by aebbmvw is predominantly mediated by na+/h+ antiport via the nha1 component of the aebbmvw in the absence of amino acids and atp. aenha1 is a na+/h+ antiporter that has been postulated to exchange na+ and h+ across the apical plasma membrane in posterior midgut of a. aegypti larvae. its principal ... | 2019 | 30392010 |
| the combinatory effect of cyt1aa flexibility and specificity against dipteran larvae improves the toxicity of bacillus thuringensis kurstaki toxins. | cyt1a98 is a novel cytolytic protein, from bupm98 bacillus thuringiensis strain, characterized by its synergistic activity with b. thuringiensis kurstaki toxins against lepidopteran larvae. in this study, we evidenced that cyt1a98 improves the toxicity of b. thuringiensis kurstaki toxins against aedes aegypti larvae. in fact, the strain bns3phtcyt1a98 exhibited a larvicidal activity of about 849-fold of that of bns3phtblue against a. aegypti. the molecular and biochemical characterizations, of c ... | 2019 | 30391590 |
| host blood-meal source has a strong impact on gut microbiota of aedes aegypti. | gut microbial communities of mosquitoes can influence vector susceptibility to pathogens, yet the factors that govern their composition remain poorly understood. we investigated the impact of host blood-meal source on gut microbiota of aedes aegypti l. adult mosquitoes were fed on human, rabbit or chicken blood and their gut microbiota compared to those of sugar-fed and newly emerged adults. microbial diversity was significantly reduced in blood-fed and sugar-fed mosquitoes but was restored to t ... | 2019 | 30357406 |
| walter reed at camp lazear: a paradigm for contemporary clinical research. | throughout the time of the early settlement and development of north america, there were frequent epidemics of yellow fever. it is thought that ships transporting captured africans likely conveyed both major vectors, the aedes aegypti mosquito and the rna yellow fever virus from africa to north america. infected ships landing in port cities resulted in epidemics that proved impossible to control with conventional interventions. walter reed and the u.s. army commission solved the mystery of the m ... | 2019 | 30327122 |
| vector competence analysis of two aedes aegypti lineages from bello, colombia, reveals that they are affected similarly by dengue-2 virus infection. | dengue is the second most prevalent vector-borne disease after malaria in colombia. it is caused by dengue virus, an arbovirus that exhibits high epidemic power, which is evidenced by its occurrence in more than 80% of the country, largely because of the extensive dispersion of the mosquito vector aedes aegypti. the existence of two lineages of ae. aegypti has been proposed based on genetic differences at the mitochondrial level, and they have been reported to circulate in similar proportions in ... | 2019 | 30298277 |
| enhanced mortality in deltamethrin-resistant aedes aegypti in thailand using a piperonyl butoxide synergist. | aedes aegypti is the primary vector of dengue viruses in thailand. control of this mosquito continues to rely heavily on use of insecticides in various forms and applications. the synergistic effect of piperonyl butoxide (pbo), combined with deltamethrin against eight populations of ae. aegypti collected from different regions in thailand is presented. the standard who adult contact bioassays found all populations with low to moderate levels of resistance to deltamethrin alone (using a 0.05% dis ... | 2019 | 30287252 |
| seasonal and spatial distribution of aedes aegypti and aedes albopictus in a municipal urban park in são paulo, sp, brazil. | dengue, yellow fever, chikungunya and zika are important arboviruses present in various countries of the world, the etiological agents of which are transmitted to human-beings by the bite of infected females of aedes aegypti and aedes albopictus. biological aspects of these vectors, such as their distribution and abundance, are influenced by climatic variables such as rainfall and temperature. we assess the spatial and seasonal distribution of ae. aegypti and ae. albopictus, during spring 2014 a ... | 2019 | 30282003 |
| vaccination and immunization strategies to design aedes aegypti salivary protein based subunit vaccine tackling flavivirus infection. | flavivirus causes arthropod-borne severe diseases that sometimes lead to the death. the flavivirus species including dengue virus, zika virus and yellow fever virus are transmitted by the bite of aedes mosquitoes. all these viral species target the people living in their respective endemic zone causing a high mortality rate. recent studies show that immune factors present in the ae. aegypti saliva is the hidden culprit promoting blood meal collection, suppressing host immune molecules and promot ... | 2019 | 30219509 |
| hypometabolic strategy and glucose metabolism maintenance of aedes aegypti egg desiccation. | the mosquito aedes aegypti is vector of several viruses including yellow fever virus, dengue virus chikungunya virus and zika virus. one of the major problems involving these diseases transmission is that a. aegypti embryos are resistant to desiccation at the end of embryogenesis, surviving and remaining viable for several months inside the egg. therefore, a fine metabolism control is essential to support these organisms throughout this period of resistance. the carbohydrate metabolism has been ... | 2019 | 30266630 |
| the intrinsically disordered c-terminal f domain of the ecdysteroid receptor from aedes aegypti exhibits metal ion-binding ability. | the dominant vector of dengue and zika diseases is a female aedes aegypti mosquito. its reproduction is controlled by the formation of an active heterodimer complex of the 20-hydroxyecdysone receptor (ecr) and ultraspiracle protein (usp). although ecr exhibits a structural and functional organization typical of nuclear receptors (nrs), the ecr c-terminus has an additional f domain (aafecr) that is rarely present in the nrs superfamily. the presence of f domains is evolutionarily not well conserv ... | 2019 | 30243841 |
| [first evidence of aedes aegypti in the arequipa region, perú 2016]. | 2019 | 30183928 | |
| susceptibility and vectorial capacity of american aedes albopictus and aedes aegypti (diptera: culicidae) to american zika virus strains. | the rapid expansion of zika virus (zikv), following the recent outbreaks of chikungunya virus, overwhelmed the public health infrastructure in many countries and alarmed many in the scientific community. aedes aegypti (l.) (diptera: culicidae) and aedes albopictus (skuse) (diptera: culicidae) have previously been incriminated as the vectors of these pathogens in addition to dengue virus. in our study, we challenged low generation ae. aegypti (chiapas, mexico) and ae. albopictus (north carolina, ... | 2019 | 30102327 |
| characterization of tolypocladium cylindrosporum (hypocreales, ophiocordycipitaceae) isolates from brazil and their efficacy against aedes aegypti (diptera, culicidae). | to survey and to characterize entomopathogenic fungi as natural enemies of mosquitoes in central brazil. | 2019 | 30160316 |
| pan-american league of associations for rheumatology-central american, caribbean and andean rheumatology association consensus-conference endorsements and recommendations on the diagnosis and treatment of chikungunya-related inflammatory arthropathies in latin america. | although mortality rates related with chikungunya (chik) outbreaks in latin america's (la's) dengue-endemic rural and new urban regions are low, dealing with symptoms and sequelae can both produce a significant burden of disease and diminish quality of life-from many months to years-after the acute phase of the infection, with a significant impact on public and individual health.the aim of this work was to establish pan-american league of associations for rheumatology-central american, caribbean ... | 2019 | 30028809 |
| encapsulation of piper aduncum and piper hispidinervum essential oils in gelatin nanoparticles: a possible sustainable control tool of aedes aegypti, tetranychus urticae and cerataphis lataniae. | the encapsulated essential oils (eos) of piper aduncum l. and piper hispidinervum c. dc. in gelatin nanoparticles were evaluated against aedes aegypti linn., tetranychus urticae koch and cerataphis lataniae boisd. | 2019 | 29971785 |
| human blood as the only source of aedes aegypti in churches from merida, yucatan, mexico. | 2019 | 29916450 | |
| lippia gracilis essential oil in β-cyclodextrin inclusion complexes: an environmentally safe formulation to control aedes aegypti larvae. | one of the most efficient ways to prevent arboviruses, such as dengue fever, yellow fever, chikungunya and zika, is by controlling their vector, the aedes aegypti. because this vector is becoming resistant to most larvicides used, the development of new larvicides should be considered. β-cyclodextrin (β-cd) complexes have been investigated as an interesting way of enabling the use of essential oils in water as larvicides. this study comprised the development of lippia gracilis essential oil (lge ... | 2019 | 29998608 |
| efficacy of lysinibacillus sphaericus against mixed-cultures of field-collected and laboratory larvae of aedes aegypti and culex quinquefasciatus. | lysinibacillus sphaericus (bacillales: planococcaceae) is a spore-forming bacillus used for the biological control of mosquitoes (diptera: culicidae) due to its larvicidal activity determined by various toxins and s-layer protein produced either during sporulation or by the vegetative cell. aedes aegypti and culex quinquefasciatus are the vectors of arboviruses that cause tropical diseases representing a current public health problem. both species may coexist in the same larval development sites ... | 2019 | 29784071 |
| a comparison of mosquito densities, weather and infection rates of aedes aegypti during the first epidemics of chikungunya (2014) and zika (2016) in areas with and without vector control in puerto rico. | in puerto rico, the first records of the transmission of chikungunya (chikv) and zika (zikv) viruses were confirmed in may 2014 and december 2015, respectively. transmission of chikv peaked in september 2014, whereas that of zikv peaked in august 2016. the emergence of these mosquito-transmitted arboviruses in the context of a lack of human population immunity allowed observations of whether the outbreaks were associated with aedes aegypti (diptera: culicidae) densities and weather. mosquito den ... | 2019 | 30225842 |
| vertebrate hosts of aedes aegypti, aedes albopictus, and culex quinquefasciatus (diptera: culicidae) as potential vectors of zika virus in florida. | zika virus (zikv), once considered an obscure pathogen, spread rapidly from 2014 to 2016 to become an internationally notifiable condition of major public health concern. the relative importance of various culex and aedes species mosquitoes (diptera: culicidae) in zikv transmission is a topic of debate. quantifying host use is important in determining the vectorial capacity of a mosquito species for transmitting zikv in nature. in the united states, few data are available on host use of aedes ae ... | 2019 | 30165498 |
| overview of dengue and zika virus similarity, what can we learn from the saudi experience with dengue fever? | there is high public health alert in the kingdom of saudi arabia concerning zika virus infection. so far, there is no reported outbreak. so are we at risk of this disease? reviewing the literature of recent outbreaks of other infectious diseases in saudi arabia may clarify the situation. it is evident that there is some similarity between zika and dengue regarding vector (aedes aegypti) which is available in the kingdom of saudi arabia. furthermore, they have similar transmission process and the ... | 2019 | 29623022 |
| analysis of cluster-randomized test-negative designs: cluster-level methods. | intervention trials of vector control methods often require community level randomization with appropriate inferential methods. for many interventions, the possibility of confounding due to the effects of health-care seeking behavior on disease ascertainment remains a concern. the test-negative design, a variant of the case-control method, was introduced to mitigate this issue in the assessment of the efficacy of influenza vaccination (measured at an individual level) on influenza infection. her ... | 2019 | 29447357 |
| evaluation of aib and peg-polymer insect kinin analogs on mosquito and tick gpcrs identifies potent new pest management tools with potentially enhanced biostability and bioavailability. | insect kinins modulate aspects of diuresis, digestion, development, and sugar taste perception in tarsi and labellar sensilla in mosquitoes. they are, however, subject to rapid biological degradation by endogenous invertebrate peptidases. a series of α-aminoisobutyric (aib) acid-containing insect kinin analogs incorporating sequences native to the aedes aegypti mosquito aedeskinins were evaluated on two recombinant kinin invertebrate receptors stably expressed in cell lines, discovering a number ... | 2019 | 30107140 |
| [coinfection of dengue and chikungunya viruses. narrative review]. | dengue and chikungunya viruses are transmitted by the female aedes aegypti and aedes albopictus, which are widely distributed in tropical and subtropical areas, facilitating coinfection. | 2019 | 31095186 |
| zika virus disease. | the zika virus is an arbovirus belonging to the virus family flaviviridae. the virus was isolated in 1947 from a rhesus monkey in the zika forest of uganda. the virus causes sporadic mild human infections in africa and later in asia. however, by 2007 a major shift in its infection pattern was noticed and thousands of human infections were reported in the state of yap and federated states of micronesia. in the last 3 years, major outbreaks have continued to occur and the virus has spread to sever ... | 2019 | 30787745 |
| associations between household environmental factors and immature mosquito abundance in quetzaltenango, guatemala. | aedes aegypti-borne diseases are becoming major public health problems in tropical and sub-tropical regions. while socioeconomic status has been associated with larval mosquito abundance, the drivers or possible factors mediating this association, such as environmental factors, are yet to be identified. we examined possible associations between proximity to houses and roads and immature mosquito abundance, and assessed whether these factors and mosquito prevention measures mediated any associati ... | 2019 | 31870343 |
| compatibility between leptolegnia chapmanii and diflubenzuron and neem oil for the control of aedes aegypti. | leptolegnia chapmanii is pathogenic to mosquito larvae. the compatibility between l. chapmanii and two insect growth regulators (igr), diflubenzuron and neem oil, was evaluated. l. chapmanii was grown on culture media containing different concentrations of each igr. the mycelial growth was significantly reduced with the highest concentrations of igr (f6,98=268, p<0.05). however, the production of zoospores (f6,56=0.93, p>0.05) and the larval mortality of aedes aegypti (f6,56=0.95, p>0.05) were n ... | 2019 | 31866096 |
| a non-conformational qsar study for plant-derived larvicides against zika aedes aegypti l. vector. | a set of 263 plant-derived compounds with larvicidal activity against aedes aegypti l. (diptera: culicidae) vector is collected from the literature, and is studied by means of a non-conformational quantitative structure-activity relationships (qsar) approach. the balanced subsets method (bsm) is employed to split the complete dataset into training, validation and test sets. from 26,775 freely available molecular descriptors, the most relevant structural features of compounds affecting the bioact ... | 2019 | 31865579 |
| nix is a male-determining factor in the asian tiger mosquito aedes albopictus. | the initial signal that governs sex determination is highly variable among insects. a homolog of nix, the male-determining factor in aedes aegypti, was previously found in the asian tiger mosquito ae. albopictus. here we show that the ae. albopictus nix (aalnix) is more complex in gene structure and splice isoforms than its ae. aegypti homolog (aaenix). aalnix shows a similar transcription profile compared to aaenix. crispr/cas9-mediated knockouts of aalnix in vivo and in the ae. albopictus c6/3 ... | 2019 | 31901476 |
| hyalodendrins a and b, new decalin-type tetramic acid larvicides from the endophytic fungus hyalodendriella sp. ponipodef12. | two new decalin/tetramic acid hybrid metabolites, hyalodendrins a (1) and b (2) were isolated from plant endophytic fungus hyalodendriella sp. ponipodef12. the structures of the new compounds were elucidated by analysis of the spectroscopic data, including nmr, hrms and ecd, and by chemical conversion. compounds 1 and 2 were phomasetin analogues, and both showed potent larvicidal activity against the fourth-instar larvae of aedes aegypti with the median lethal dose (lc50) values of 10.31 and 5.9 ... | 2019 | 31892246 |
| co-occurrence of kdr mutations v1016i and f1534c and its association with phenotypic resistance to pyrethroids in aedes aegypti (diptera: culicidae) populations from costa rica. | aedes aegypti (linnaeus, 1762) is considered the most important mosquito vector species for several arboviruses (e.g., dengue, chikungunya, zika) in costa rica. the primary strategy for the control and prevention of aedes-borne diseases relies on insecticide-based vector control. however, the emergence of insecticide resistance in the mosquito populations presents a significant threat to these prevention actions. the characterization of the mechanisms driving the insecticide resistance in ae. ae ... | 2019 | 31891404 |
| risk of dengue in central africa: vector competence studies with aedes aegypti and aedes albopictus (diptera: culicidae) populations and dengue 2 virus. | dengue is the most important mosquito-borne diseases worldwide but was considered scarce in west-central africa. during the last decade, dengue outbreaks have increasingly been reported in urban foci in this region suggesting major epidemiological changes. however, in central africa where both vectors, aedes aegypti and aedes albopictus are well established, the role of each species in dengue transmission remains poorly investigated. | 2019 | 31887138 |
| diverse sensitivities of trpa1 from different mosquito species to thermal and chemical stimuli. | temperature and odors profoundly affect the behavior of animals. transient receptor potential channel, subfamily a, member 1 (trpa1) functions as a polymodal nociceptor for sensing both vital environmental cues in insects. mosquitoes are recognized as disease vectors, and many efforts have been devoted to investigations of their host-seeking behaviors and repellents. however, the physiological characteristics of mosquito trpa1 have not been systematically studied. we identified multiple alternat ... | 2019 | 31882848 |
| spatial risk distribution of dengue based on the ecological niche model of aedes aegypti (diptera: culicidae) in the central mexican highlands. | dengue is the most important viral disease transmitted by mosquitoes, predominantly aedes (stegomyia) aegypti (l.) (diptera:culicidae). forty percent of the world's population is at risk of contracting the disease, and a large area of mexico presents suitable environmental conditions for the life cycle of ae. aegypti. in particular, the central mexican highlands have a high population density, increasing the risk of transmission and propagation of dengue. in the present study, the potential dist ... | 2019 | 31880769 |
| effect of d-allethrin aerosol and coil to the mortality of mosquitoes. | commercial insecticides were widely used by communities to control the mosquito population in their houses. d-allethrin is one of insecticide ingredients widely distributed in two different concentrations namely 0.15% of aerosol and 0.3% of coil formulations. we aimed to understand the mortality of indoor mosquitoes after being exposed to d-allethrin 0.15% (aerosol) and 0.3% (coil) formulations. | 2019 | 31879666 |
| clustering of zika viruses originating from different geographical regions using computational sequence descriptors. | in this report we consider a data set, which consists of 310 zika virus genome sequences taken from different continents, africa, asia and south america. the sequences, which were compiled from genbank, were derived from the host cells of different mammalian species (simiiformes, aedes opok, aedes africanus, aedes luteocephalus, aedes dalzieli, aedes aegypti, and homo sapiens). for chemometrical treatment the sequences have been represented by sequence descriptors derived from their graphs or ne ... | 2019 | 31878862 |
| geographical distribution of aedes aegypti aegypti and aedes aegypti formosus (diptera: culicidae) in kenya and environmental factors related to their relative abundance. | the mosquito aedes aegypti (l.) is the primary vector of various infectious viruses and is typified by a polymorphic color and abundance of white scales on the body. it has been conventionally separated into two subspecies, ae. aeg. formosus (walker) (aaf) and ae. aeg. aegypti (l.) (aaa), with aaf considered a 'sylvan' form and aaa a 'domestic' form. because the two subspecies show different susceptibilities to dengue viruses it is important to understand their distribution. in this study, we co ... | 2019 | 31815285 |
| vgsc-interacting proteins are genetically associated with pyrethroid resistance in aedes aegypti. | association mapping of factors that condition pyrethroid resistance in aedes aegypti has consistently identified genes in multiple functional groups. toward better understanding of the mechanisms involved, we examined high throughput sequencing data (hts) from two aedes aegypti aegypti collections from merida, yucatan, mexico treated with either permethrin or deltamethrin. exome capture enrichment for coding regions and the aaegl5 annotation were used to identify genes statistically associated w ... | 2019 | 30695054 |
| susceptibility profile of aedes aegypti l. (diptera: culicidae) from montclair, california, to commonly used pesticides, with note on resistance to pyriproxyfen. | the peridomestic anthropophilic aedes aegypti l. (diptera: culicidae) is originated from the wild zoophilic subspecies aedes aegypti formosus in sub-saharan africa, and currently has a broad distribution in human-modified environments of the tropics and subtropics worldwide. in california, breeding populations were initially detected in 2013 in the cities of fresno, madera, and san mateo, and now can be found in 188 cities of 12 counties in the state. recent genetic studies suggest that this spe ... | 2019 | 30810751 |
| dirofilaria and wolbachia in mosquitoes (diptera: culicidae) in central european russia and on the black sea coast. | dirofilariasis is endemic in russia, as well as in many other european countries. the aim of this study was to assess the ability of mosquitoes to transfer dirofilaria immitis and dirofilaria repens in regions with temperate and subtropical climates. the possible impact of the symbiotic bacterium wolbachia on dirofilaria transmission was also investigated. 5333 female mosquitoes were collected at 11 points in central european russia and on the black sea coast during the period 2013-2017. out of ... | 2019 | 30644356 |
| lemongrass and cinnamon bark: plant essential oil blend as a spatial repellent for mosquitoes in a field setting. | plant essential oils (eos) have been considered as spatial repellents to help disrupt the pathogen transmission cycle of mosquitoes. our objective was to assess spatial repellency effects of eos on the tropical yellow fever mosquito, aedes aegypti (l.) (diptera: culicidae) and on local mosquito populations in coastal british columbia (canada). in laboratory experiments using protocols of the world health organization, three of the solitary eos tested proved repellent to ae. aegypti: cinnamon bar ... | 2019 | 31143941 |
| haemagogus leucocelaenus and haemagogus janthinomys are the primary vectors in the major yellow fever outbreak in brazil, 2016-2018. | the yellow fever virus (yfv) caused a severe outbreak in brazil in 2016-2018 that rapidly spread across the atlantic forest in its most populated region without viral circulation for almost 80 years. a comprehensive entomological survey combining analysis of distribution, abundance and yfv natural infection in mosquitoes captured before and during the outbreak was conducted in 44 municipalities of five brazilian states. in total, 17,662 mosquitoes of 89 species were collected. before evidence of ... | 2019 | 30866775 |
| bioefficacy of two nonpyrethroid insecticides for targeted indoor residual spraying against pyrethroid-resistant aedes aegypti. | we evaluated the efficacy of bendiocarb (ficam w® 80%) and pirimiphos-methyl (actellic 300cs® 28.16%), applied to different surfaces potentially sprayable within houses during the application of a targeted indoor residual spraying (tirs) against a field pyrethroid-resistant strain of aedes aegypti. bioassays with cones were performed on cement (walls), wood (doors), and textile (cloth) surfaces within typical houses in the mexican city of merida (n = 10). optimal residual efficacy (>80% of mean ... | 2019 | 31922939 |
| discriminating lethal concentrations for transfluthrin, a volatile pyrethroid compound for mosquito control in thailand. | pyrethroids are commonly used to control malaria and dengue vectors in thailand. the lack of specific lethal discriminating concentrations (dcs) for specific mosquito species has possibly compromised more accurate assessments of physiological susceptibility to various chemicals over time. previous studies have established dcs of various residual pyrethroids against specific mosquitoes in thailand. however, dcs for transfluthrin (tft), a highly volatile pyrethroid compound, against mosquito vecto ... | 2019 | 31922934 |
| vector competence of aedes bromeliae and aedes vitattus mosquito populations from kenya for chikungunya virus. | kenya has experienced outbreaks of chikungunya in the past years with the most recent outbreak occurring in mandera in the northern region in may 2016 and in mombasa in the coastal region from november 2017 to february 2018. despite the outbreaks in kenya, studies on vector competence have only been conducted on aedes aegypti. however, the role played by other mosquito species in transmission and maintenance of the virus in endemic areas remains unclear. this study sought to determine the possib ... | 2018 | 30321181 |
| bacillus wiedmannii biovar thuringiensis: a specialized mosquitocidal pathogen with plasmids from diverse origins. | bacillus cereus sensu lato also known as b. cereus group is composed of an ecologically diverse bacterial group with an increasing number of related species, some of which are medically or agriculturally important. numerous efforts have been undertaken to allow presumptive differentiation of b. cereus group species from one another. fcc41 is a bacillus sp. strain toxic against mosquito species like aedes aegypti, aedes (ochlerotatus) albifasciatus, culex pipiens, culex quinquefasciatus, and culex ... | 2018 | 30285095 |
| positional stable isotope tracer analysis reveals carbon routes during ammonia metabolism of aedes aegypti mosquitoes. | in aedes aegypti females, the ammonia released during blood meal digestion is partially metabolized to facilitate the disposal of excess nitrogen. in this study, we used low- and high-resolution liquid chromatography-mass spectrometry (lc/ms) techniques to investigate the role of glucose during ammonia detoxification. mosquitoes were fed a blood meal supplemented with [1,2-13c2]glucose, and downstream metabolites were measured for 24 h. quantification of [13c] amino acids in the entire mosquito ... | 2018 | 28970248 |
| using maldi-tof ms to identify mosquitoes collected in mali and their blood meals. | matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) has been recently described as an innovative and effective tool for identifying arthropods and mosquito blood meal sources. to test this approach in the context of an entomological survey in the field, mosquitoes were collected from five ecologically distinct areas of mali. we successfully analysed the blood meals from 651 mosquito abdomens crushed on whatman filter paper (wfps) in the field using maldi-t ... | 2018 | 29409547 |
| modulation of host learning in aedes aegypti mosquitoes. | how mosquitoes determine which individuals to bite has important epidemiological consequences. this choice is not random; most mosquitoes specialize in one or a few vertebrate host species, and some individuals in a host population are preferred over others. mosquitoes will also blood feed from other hosts when their preferred is no longer abundant, but the mechanisms mediating these shifts between hosts, and preferences for certain individuals within a host species, remain unclear. here, we sho ... | 2018 | 29395917 |
| the spatial and temporal scales of local dengue virus transmission in natural settings: a retrospective analysis. | dengue is a vector-borne disease caused by the dengue virus (denv). despite the crucial role of aedes mosquitoes in denv transmission, pure vector indices poorly correlate with human infections. therefore there is great need for a better understanding of the spatial and temporal scales of denv transmission between mosquitoes and humans. here, we have systematically monitored the circulation of denv in individual aedes spp. mosquitoes and human patients from caratinga, a dengue endemic city in th ... | 2018 | 29394906 |
| natural vertical transmission of dengue virus in aedes aegypti and aedes albopictus: a systematic review. | dengue is of great concern in various parts of the world, especially in tropical and subtropical countries where the mosquito vectors aedes aegypti and aedes albopictus are present. the transmission of this virus to humans, by what is known as horizontal transmission, occurs through the bite of infected females of one or other of the two mosquito species. furthermore, an infected female or male parent, by what is known as vertical transmission, can transfer this arbovirus to some part of their o ... | 2018 | 29391071 |
| altered vector competence in an experimental mosquito-mouse transmission model of zika infection. | few animal models of zika virus (zikv) infection have incorporated arthropod-borne transmission. here, we establish an aedes aegypti mosquito model of zikv infection of mice, and demonstrate altered vector competency among three strains, (orlando, orl, ho chi minh, hcm, and patilas, pat). all strains acquired zikv in their midguts after a blood meal from infected mice, but zikv transmission only occurred in mice fed upon by hcm, and to a lesser extent pat, but not orl, mosquitoes. this defect in ... | 2018 | 29505571 |
| effects of climate change on the spread of zika virus: a public health threat. | zika is a vector-borne viral disease transmitted to humans primarily by aedes aegypti mosquitoes. the increased climate instability has contributed to the emergence of infections carried by mosquitoes like dengue, chikungunya and zika. while infection with the zika virus is not new, the recent epidemic of microcephaly in brazil and other countries in south america resulting from the infection of pregnant women with the zika virus raise a number of serious public health concerns. these include th ... | 2018 | 29500926 |
| diurnal temperature range and chikungunya virus infection in invasive mosquito vectors. | climate strongly influences the geographic distribution and timing of mosquito-borne disease outbreaks. environmental temperature affects phenotypic traits of mosquitoes including vector competence for arboviruses mediated by changes in infection, extrinsic incubation period and in rates of transmission. most experiments, however, are done at constant temperatures. in nature, mosquitoes are more likely to experience daily fluctuations in temperature. here we compare disseminated infection (leg i ... | 2018 | 29040730 |