Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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anti-eosinophilic effect of lafoensia pacari in toxocariasis. | we previously reported the anti-inflammatory activity of lafoensia pacari extract in toxocara canis infection, a model of systemic il-5-dependent eosinophil migration. in the present study, we describe the kinetics of the anti-inflammatory activity of l. pacari extract and compare it with dexamethasone. t. canis-infected mice were submitted to different treatment protocols and the cells present in bronchoalveolar space and peritoneal cavity were collected at the end of each treatment period. the ... | 2008 | 17949961 |
decontamination by anaerobic stabilisation of the environment contaminated with enteronematode eggs toxocara canis and ascaris suum. | investigations were carried out under operating conditions of field composting factory in brezno (slovak republic) to determine the effect of anaerobic stabilization of organic wastes from public areas on the survival of model helminth toxocara canis and ascaris suum eggs. due to anaerobic conditions, low temperature, low c:n ratio and changes in physical and chemical properties of organic waste, less than 64% of a. suum eggs remained viable after 150 days of stabilisation. the anaerobic stabili ... | 2008 | 17976979 |
comment on "epilepsy and seropositivity rates of toxocara canis and toxoplasma gondii". | 2008 | 17977752 | |
efficacy of eprinomectin against toxacara canis in dogs. | this study was made to investigate efficacy of eprinomectin against to toxocara canis in dogs. in the study, 20 stray dogs naturally infected with t. canis were divided into two groups as treatment (ten dogs) and control (ten dogs). eprinomectin (100 microg/kg, eprinex 250 ml) was given to treatment group dogs orally, and eggs per gram were determined in the faeces on the day of pre-treatment and the second, fourth, sixth, eighth and tenth days of post-treatment. no side effects associated with ... | 2008 | 17992540 |
anti-inflammatory effects of lafoensia pacari and ellagic acid in a murine model of asthma. | we have shown that the ethanolic extract of lafoensia pacari inhibits eosinophilic inflammation induced by toxocara canis infection, and that ellagic acid is the secondary metabolite responsible for the anti-eosinophilic activity seen in a model of beta-glucan peritonitis. in the present study, we investigated the preventive and curative effects of l. pacari extract and ellagic acid on allergic lung inflammation using a murine model of ovalbumin-induced asthma. in bronchoalveolar lavage fluid, p ... | 2008 | 18021768 |
epidemiology of intestinal helminth parasites of dogs in ibadan, nigeria. | an epidemiological study of gastrointestinal helminths of dogs (canis familiaris) in two veterinary clinics in ibadan, nigeria, was conducted between january 2001 and december 2002. faecal samples collected from 959 dogs were processed by modified kato-katz technique and then examined for helminth eggs. the results of the study showed that 237 (24.7%) of the dogs examined were infected with different types of helminths. the prevalences for the various helminth eggs observed were: toxocara canis ... | 2008 | 18053301 |
experimental infection of the cockroach periplaneta americana with toxocara canis and the establishment of patent infections in pups. | the possible role of the cockroach periplaneta americana in the transmission of toxocara canis eggs and larvae via faeces and tissue migration was studied. cockroaches fed with 3 x 105 and 5 x 105 embryonated eggs were found to harbour viable eggs and larvae from days 1 to 5 post-infection (dpi). at necropsy on 5 dpi, eggs and larvae were also recovered from the rectal contents but not from the tissues of cockroaches. in addition patent infections were established in pups fed on infected faeces ... | 2008 | 18053303 |
identification of stage-specific proteins of angiostrongylus vasorum (baillet, 1866) kamensky. | sera of ten dogs infected with angiostrongylus vasorum were analyzed by immunoblotting proteins of first stage larvae (l1) and adult parasites. the molecular weights (m.w.) of the principal l1 proteins identified by igg, igm, iga, and ige were 18-118 kda and those of the adult parasite were 28-209 kda. the l1 proteins had not been recognized by igg, igm, and iga antibodies in sera of dogs naturally infected with toxocara canis, ancylostoma caninum, and dipylidium caninum, although only weakly by ... | 2008 | 18060430 |
diagnosis of ocular toxocariasis by establishing intraocular antibody production. | to investigate the role of toxocara canis in posterior uveitis of undetermined origin. | 2008 | 18061138 |
epilepsy and toxocariasis: a case-control study in italy. | to assess the relationship between epilepsy and toxocariasis in adult subjects by means of a case-control study in catania, italy. | 2008 | 18031545 |
inducible nitric oxide synthase inhibition influenced granuloma formation with suppressed collagen expression in myositis caused by toxocara canis in mice. | the role of nitric oxide (no) in granuloma pathology is largely unclear to date. we investigated the role of no in fibrotic granuloma development in the musculature of mice infected with toxocara canis from 1 day (dpi) to 8 weeks post-infection (wpi) using the no synthase (nos) inhibitors, l-nil (l-n6-1-iminoethyl lysine). in infected mice, elevated serum no concentrations were seen at 1 dpi (204.1 +/- 0.2 microm) and 1 wpi (145.1 +/- 0.2 microm); it declined drastically from 4 wpi onwards (57.0 ... | 2008 | 18034265 |
pcdna-il-12 vaccination blocks eosinophilic inflammation but not airway hyperresponsiveness following murine toxocara canis infection. | we have investigated the effect of pcdna3-cpg and pcdna-il-12, delivered by intradermal gene gun administration, on the blood/lung eosinophilia, airway hyperresponsiveness as well as the immune response in a murine model of toxocariasis. our results demonstrated that pcdna-il-12 but not pcdna3-cpg vaccination led to a persistent lower blood/bronchoalveolar eosinophilia following toxocara canis infection, as pcdna3-cpg led only to an early transient blockage of eosinophil transmigration into bron ... | 2008 | 18083279 |
experimental toxocariosis in balb/c mice: effect of the inoculation dose on brain and eye involvement. | ocular toxocarosis (ot) is a well-established disease. however, our understanding of the migratory route, time and circumstances that produce ocular invasion are not clear. to improve our knowledge of factors related to ocular invasion, balb/c mice were inoculated with simple doses (sd) of 6, 12, 50, 100, 200 and 1000 embryonated eggs (ee) and multiple doses (md) of 200 and 1000 ee. brains and eyes were studied for the presence of larvae in animals sacrificed on days 3, 5, 7, 9, 11, 13, 15, 17, ... | 2008 | 18093569 |
preliminary evidence of nitazoxanide activity on toxocara canis in a mouse model. | 2008 | 18093807 | |
infection with the roundworm toxocara canis leads to exacerbation of experimental allergic airway inflammation. | epidemiological studies performed in developing as well as in western countries suggest that infection with toxocara canis contributes to the development of atopic diseases. | 2008 | 18167123 |
enhanced expression of transforming growth factor-beta 1 in inflammatory cells, alpha-smooth muscle actin in stellate cells, and collagen accumulation in experimental granulomatous hepatitis caused by toxocara canis in mice. | although toxocaral granulomatous hepatitis (tgh) characterized with a dominant-th2 type immune response is a self-limiting disease, little is known concerning the role of fibrosis-related cytokine transforming growth factor-beta 1 (tgf-beta 1) in pathogenesis of tgh. a detailed histological and quantitatively immunohistochemical analysis of tgf-beta 1, alpha-smooth muscle actins (alpha-sma), and collagen was performed on the liver tissues from mice infected with toxocara canis as assessed betwee ... | 2008 | 18178169 |
determination of the relative avidity of the specific igg antibodies in human toxocariasis. | human toxocariasis is a zoonosis caused by infection with larvae of the ascarid nematode toxocara canis and, less frequently, t. cati. our study developed a method for distinguishing distant from recent human toxocariasis by assessing the avidity of the igg antibodies. the avidity of specific antibodies increases with time after antigen challenge and assessment of the degree of avidity can be used to discriminate between recent and distant infections. the relative avidity was measured in 150 ser ... | 2008 | 18179629 |
patent toxocara canis infections in previously exposed and in helminth-free dogs after infection with low numbers of embryonated eggs. | the outcome of toxocara canis infections in the canine host depends on the migratory pathway of parasite larvae (somatic or tracheal) which is considered to be related to the host's age and its immune status. however, field studies attest high prevalences of patent t. canis infections in adult animals. the controlled induction of patent infections with low doses of embryonated eggs was investigated in 18 beagles in a 7-month study until their 16th life month. the animals were assigned to three g ... | 2008 | 18201825 |
the investigation of toxocara canis eggs in coats of different dog breeds as a potential transmission route in human toxocariasis. | this study was undertaken to determine the prevalence of toxocara canis eggs on the coats of dogs (a potential etiological factor for human toxocariasis) and to see if there were mainly a dog breed and coat type effects for the presence of eggs on the coat. hair samples were collected from the different breeds of 51 domestic pet dogs and examined for the presence of t. canis eggs. a total of 62 t. canis eggs (all viable) were found in 21.56% of the dogs. forty-nine (79.03%) of the eggs recovered ... | 2008 | 18207641 |
seroepidemiological survey for toxocara canis infection in the northwestern part of turkey. | in this study, an elisa with toxocara canis antigen was used for the determination of sero-epidemiological survey of toxocara canis infection in urban and rural areas of northwestern part of turkey. toxocara seroprevalance was detected among randomly selected 430 children in the rural areas and 141 children in the urban areas. total seroprevalence rate of toxocara antibodies was found as 12.95% in both groups. while significant levels of anti-toxocara antibodies were detected in 73 out of 430 (1 ... | 2007 | 18224618 |
[frequency of the antibody anti-toxocara canis in a community along the uatumã river, state of amazonas]. | a cross-sectional study was carried out in the waimiri and atroari settlements in balbina, between july and october 2006, with the aims of estimating the frequency of the antibody anti-toxocara canis of the igg class and studying the epidemiological and sociocultural variables. thirty-four families were studied and 100 individuals were included, corresponding to 5% (100/2000) of the population of the settlements. the age range was 0-76 years (mean = 22.9; standard deviation = 18). the gender dis ... | 2007 | 18200421 |
ocular toxocariasis in a child: a case report from kashmir, north india. | toxocariasis is an important zoonotic disease caused by the second stage larva of toxocara canis or toxocara cati . the typical clinical syndromes of toxocariasis in humans are visceral and ocular toxocariasis. ocular toxocariasis may presents as peripheral inflammatory mass, posterior pole granuloma and endophthalmitis. we report a serologically confirmed case of ocular toxocariasis in 12-year-old female. the diagnosis was confirmed by detection of anti- toxocara antibodies in aqueous and vitre ... | 2007 | 18087098 |
[historical review on the development of medical parasitology in china during the years of 1871-2006]. | the present review deals with the representative research papers on human parasites and parasitic diseases in china over the past hundred years (1871-2006). as the views focused on the development of the medical parasitology, the historical background and progressive characters in the period of fermentation, origination, and expansion have been discussed. the check list of the first cases of human parasitic diseases reported in china during 1871-2006 contained 128 species of parasitic pathogens, ... | 2007 | 18038794 |
prevalence of zoonotic nematode species in dogs in lancashire. | 2007 | 18065815 | |
[a comparison of soil contamination with toxocara canis and toxocara cati eggs in rural and urban areas of wielkopolska district in 2000-2005]. | the aim of the studies was to compare the degree of soil contamination with toxocara canis and t. cati eggs in rural and urban areas depending on time of sampling and type of places examined. material and methods. over 2000-2005 a total of 538 soil samples from 3 villages and 368 from poznaĆ city (poland) areas were examined for toxocara spp. eggs. in spring 418 samples in rural areas and 184 samples in urban areas were collected and in autumn 120 and 184 respectively. the samples were examined ... | 2007 | 18075154 |
eosinophilic cholecystitis as a rare manifestation of visceral larva migrans. | eosinophilic cholecystitis is an infrequent form of cholecystitis. the etiology of eosinophilic cholecystitis is still obscure, and it is sometimes accompanied with several complications, but a simultaneous onset with pericarditis is very rare. we would like to make an alternative interpretation of our recent report "kaji k, yoshiji h, yoshikawa m, yamazaki m, ikenaka y, noguchi r, sawai m, ishikawa m, mashitani t, kitade m, kawaratani h, uemura m, yamao j, fujimoto m, mitoro a, toyohara m, yosh ... | 2007 | 18023114 |
neurotoxocarosis. | infection of humans with embryonated eggs of toxocara canis (larva migrans) remains asymptomatic, or results in covert or common toxocarosis, visceral larva migrans syndrome, or ophthalmologic and neurologic impairment. though neurological manifestations of toxocara canis larvae are rare, toxocarosis remains an important differential diagnosis of various neurological disorders. manifestations of the central nervous system are dementia, meningo-encephalitis, myelitis, cerebral vasculitis, epileps ... | 2007 | 18026633 |
an unusual case of toxocara canis of the ascending colon. | a 52-year-old cypriot woman was admitted to the surgical department of larnaca general hospital complaining of diarrhea and pain in the right upper and lower quadrants, which was reproduced by clinical examination. a palpable mass was also felt in the region. the white blood cell count was 8420/mul: 73.9% neutrophils, 13.3% lymphocytes and 6.9% eosinophils. erythrocyte sedimentation rate was 80 mm/h. parasitic examination of the stools was negative. a colonoscopy located a small mass near the il ... | 2007 | 17998843 |
prevalence and intensity of toxocara canis (werner, 1782) in dogs and its potential public health significance in ile-ife, nigeria. | a study on the prevalence and intensity of toxocara canis (werner, 1782) in dogs was carried out in ile-ife, nigeria. faecal samples were collected from 269 dogs between january and december 2004, processed by the kato-katz technique and then examined for t. canis eggs. the prevalence of t. canis obtained was 33.8%. the intensity of infection, measured as mean egg count per gram of faeces ( +/- sem) was 393.8 +/- 83.4. the prevalence and intensity of t. canis in dogs aged 0-6 months were signifi ... | 2007 | 18005468 |
the immune response to toxocariasis does not modify susceptibility to mycobacterium tuberculosis infection in balb/c mice. | mycobacterium tuberculosis and helminth infections coincide geographically and are classically described as th1 and th2 pathologies. there is much interest in exploring how concurrent worm infections might alter immune responses to mycobacterial infection. to explore this issue, mice were infected with toxocara canis and co-infected with m. tuberculosis. mice infected with m. tuberculosis had high numbers of neutrophils and mononuclear cells within the alveolar spaces, with increased parenchymal ... | 2007 | 17978073 |
echinococcosis in dogs in urban and rural areas in dakahlia governorate, egypt. | a sample of one hundred and ninety stray dogs was captured from mansoura city (urban) and three hundreds and fifty stray dogs were captured from meet el-korama, mansheit el-badawy villages (rural). the total prevalence of e. granulosus was 5%, with a worm burden ranging from 4 to 1010 (mean = 421). the significant prevalence was 6% in the rural area and 3.2% in the urban one. e. granulosus showed higher prevalence in young than old dogs and in males than females but without significant differenc ... | 2007 | 17985582 |
echinococcosis granulosus in stray dogs and echino-ihat in the hunters in cairo, egypt. | a total of fifty stray dogs of both sex and of different ages were examined for natural infection with echinococcus granulosus after post-mortem. three main intestinal helminthes were recovered. these were in descending order of abundance dipylidium caninum, toxocara canis and e. granulosus. the latter worm was demonstrated in eight of them (16%). the sera of three out of 21 dog-hunters (14.3%) showed positive echino-ihat. two of the hunters suffered enterobius vermicularis and one of them had t ... | 2007 | 17985585 |
western blot antibody determination in sera from patients diagnosed with anisakis sensitization with different antigenic fractions of anisakis simplex purified by affinity chromatography. | using western blot techniques, the specificities of crude and purified (pak and pas) anisakis simplex antigens were compared against 24 sera from patients diagnosed with anisakis sensitization. all patients recognized a 60 kda protein against the a. simplex crude extract, while 37.5% and 12.5% reacted with proteins of 40 and 25 kda, respectively, when igg was tested. in the case of ige determination, 41.6% of sera were negative, while 12.5% and 20.8% appeared to cross-react against toxocara cani ... | 2007 | 17974043 |
a comparison of the protein constituents of the major body compartments of the dog roundworm, toxocara canis. | an analysis of the protein profiles of intact worms and isolated tissues of adult male and female toxocara canis worms was conducted. soluble proteins recovered from homogenized whole specimens and dissected tissues (body wall, reproductive tract, esophagus and intestine) of t. canis adults from several different canine hosts were separated by size using gradient sodium dodecyl sulfate electrophoresis (sds-page) and visualized with silver staining. sds-page profiles of worms from different hosts ... | 2007 | 17949909 |
[toxocara canis myelitis]. | 2007 | 17305066 | |
toxocariasis in japan. | toxocariasis has long been considered a parasitic disease affecting pet owners and children who often play in sandboxes at public parks. recent cases of this animal-borne infection, however, indicate that its clinical manifestations and etiologies are changing. in this article, we will describe the critical characteristic features of toxocariasis alongside the contributions of japanese researchers to a better understanding of the disease. | 2007 | 17317275 |
[experimental ocular larva migrans infection in mice]. | to characterize the histologic alterations in the ocular globe of mice infected with eggs of toxocara canis, during both the acute and chronic stages of the infection. | 2007 | 17323248 |
echinococcus multilocularis and toxocara canis in urban red foxes (vulpes vulpes) in brussels, belgium. | during the last decades, european red foxes (vulpes vulpes) have been implicated in the transmission of several viral or parasitic pathogenic agents to domestic animals and humans. in urban areas, risks of zoonoses transmission are likely to increase as a result of a higher rate of intra- and inter-species contacts. foxes occur on 35% of the brussels-capital region area and local densities reach up to 4 family groups per square kilometre. according to the directive 2003/99/ecc, a first survey fo ... | 2007 | 17324480 |
prevalence of toxocara-induced liver granulomas, detected by immunohistochemistry, in a series of autopsies at a children's reference hospital in vitoria, es, brazil. | the aim of this investigation was to study the frequency of visceral larva migrans (vlm) granulomas in autopsies at a children's reference hospital in vitoria, es brazil, where anti-toxocara antibodies are frequently detected in the serum of children admitted at the hospital. two liver fragments from 310 autopsies of children aged between 1 and 15 years were paraffin embedded, and sections were stained with hematoxylin and eosin and submitted to detection of toxocara antigens using a rabbit anti ... | 2007 | 17333262 |
small animal deworming protocols, client education, and veterinarian perception of zoonotic parasites in western canada. | questionnaires were mailed to veterinarians in western canada to determine dog and cat deworming protocols and the association between perceived zoonotic risk and perceived prevalence of endoparasites and deworming protocols. of the responding veterinarians (545), 13% and 39% recommended deworming protocols consistent with established guidelines for puppies and kittens, respectively. mixed animal practitioners and high-perceived prevalence of toxocara cati were associated with increased appropri ... | 2007 | 17436903 |
a simple and inexpensive in vitro method for retrieving fertilized toxocara canis eggs. | the erratic migration of nematode larvae is potentially deleterious for humans, especially those produced by toxocara roundworms. diagnosis of human toxocariosis: visceral larva migrans depends on antibody detection against excretions-secretions (e/s) from toxocara larvae by enzyme-linked immunosorbent assay. in the present work, we wish to propose a simple and cheap culture procedure for keeping t. canis female worms alive. we removed living worms from the small intestine of euthanized puppies ... | 2007 | 17473936 |
pars plana vitrectomy revealed toxocara canis organism. | the toxocara organism may cause direct injury to the eye, but most commonly, host inflammatory reactions are responsible for the resulting compromise. the inflammatory response created by the ocular involvement may result in epiretinal membrane formation, tractional or combined tractional-rhegmatogenous retinal detachment. the treatment of choice is pars plana vitrectomy (ppv), which also has diagnostic significance. | 2007 | 17486297 |
epilepsy and toxocariasis: a case-control study in burundi. | a case-control study to assess the relationship between epilepsy and toxocariasis was carried out in the kiremba population, burundi. | 2007 | 17508999 |
toxocara canis: proteinases in perivitelline fluid from hatching eggs. | developing larvae of toxocara canis may secrete several kinds of enzymes within the egg perivitelline fluid (epf) prior to and during hatching. in particular, proteinases in epf could play a role in larval emergence within the host gastrointestinal lumen but its presence and nature is unknown. in this work, proteolytic activities in hatching fluid of t. canis were identified and analysed by substrate gel electrophoresis at different ph values and by using type specific protease inhibitors. three ... | 2007 | 17517477 |
pcr tools for the verification of the specific identity of ascaridoid nematodes from dogs and cats. | based on the sequences of the internal transcribed spacers (its-1 and its-2) of nuclear ribosomal dna (rdna) of toxocara canis, toxocara cati, toxocara malaysiensis and toxascaris leonina, specific forward primers were designed in the its-1 or its-2 for each of the four ascaridoid species of dogs and cats. these primers were used individually together with a conserved primer in the large subunit of rdna to amplify partial its-1 and/or its-2 of rdna from 107 dna samples from ascaridoids from dogs ... | 2007 | 17532185 |
canine parasitic zoonoses in bangkok temples. | fecal samples were collected from 204 humans and 229 dogs from 20 different temples in bangkok, as well as communities in the surrounding temple ground areas. human and dog stool samples were examined for intestinal parasites including giardia using zinc sulfate flotation and microscopy. hookworms were the most common parasite in dogs (58.1%) followed by trichuris (20.5%), isospora (10%), giardia (7.9%), toxocara (7.4%), dipylidium caninum (4.4%) and spirometra (3.1%). blastocystis hominis (5.9% ... | 2007 | 17539273 |
epidemiological study of non-systemic parasitism in dogs in southeast mediterranean spain assessed by coprological and post-mortem examination. | the prevalence and risk factors of non-systemic canine ecto- and endoparasitism and anthelminthic use in murcia located at the centre of the spanish mediterranean coastal arch, was investigated by coprology and necropsy in up to 275 pet, city shelter and stray dogs in 2001-2004. faecal parasite stages were detected in 25% of dogs. species frequency was 6-10% for toxocara canis, ancylostomatidae spp., toxascaris leonina and isospora canis, and 0.4-1% for trichuris vulpis, giardia lamblia, and dip ... | 2007 | 17542962 |
[a case of visceral larva migrans due to toxocara canis showing varied manifestations]. | a 21-year-old woman admitted for a low-grade fever, dry cough, polyarthralgia, and general fatigue was found to have elevateal accustomed to eating raw meat and cattle liver peripheral blood eosinophil counts and serum ige. chest x-ray imaging and computed tomography (ct) showed multiple small nodules in both lung fields. a multiple dot-elisa assay of her serum showed that she had visceral larva migrans caused by ascaris suum or toxocara canis. following treatment with albendazole, she developed ... | 2007 | 17564121 |
gastrointestinal parasites of shepherd and hunting dogs in the serres prefecture, northern greece. | a total of 281 faecal samples from owned shepherd and hunting dogs were collected in the serres prefecture, northern greece and were examined for the presence of intestinal parasites. the overall prevalence of parasitism was 26% and the 11 species found were: toxocara canis (12.8%), trichuris vulpis (9.6%), giardia spp. (4.3%), isospora (cystoisospora) spp. (3.9%), ancylostoma/uncinaria spp. (2.8%), cryptosporidium spp. (2.8%), alaria alata (2.5%), strongyloides stercoralis (1.8%), angiostrongyl ... | 2007 | 17573197 |
toxocara canis: molecular cloning, characterization, expression and comparison of the kinetics of cdna-derived arginine kinase. | arginine kinase (ak) is a member of a highly conserved family of phosphagen kinases. we determined the cdna sequence of toxocara canis ak, cloned it in pmal plasmid and expressed it in escherichia coli as a fusion protein with maltose-binding protein. the protein has a theoretical molecular mass of 45,376 da and an estimated isoelectric point (pi) of 8.38. alignment of the cdna-derived amino acid sequence of t. canis ak with other phosphagen kinase sequences showed high amino acid identity with ... | 2007 | 17574244 |
toxocariasis presenting with multiple effusions in the pericardial space, thoracic cavity, and morrison's pouch. | 2007 | 17575389 | |
echinococcosis (zoonotic hydatidosis) in street dogs in urban and rural areas, dakahlia governorate, egypt. | a total of one hundred and ninety street dogs were captured from urban area, mansoura district and three hundreds and fifty from rural area, met el-korama and adjacent villages (manshet el-badawy, talka center). the overall prevalence of echinoccocus granulosus was 5%, with a worm burden ranging from 4 to 1010 (mean = 421). the prevalence was 6% in rural locality and 3.2% in urban locality. e. granulosus in dogs was significantly higher in rural areas but, without significant difference in puppi ... | 2007 | 17580584 |
[nematophagous fungi of toxocara canis eggs in a public park of la plata, argentina]. | fungi have showed a great potential for the biological control of nematodes. however, they have not been evaluated for the control of animal and/or human parasites transmitted by egg contaminated soils. environmental contamination with toxocara spp. eggs is a public health problem. accidental swallowing of toxocara canis eggs (a nematode of dogs) usually results on a zoonotic infection (toxocarosis). the objectives of this research were: 1) to test the presence of antagonistic fungi against t. c ... | 2007 | 17592887 |
gastrointestinal nematodes in dogs from debre zeit, ethiopia. | the study was conducted during the period between january 2005 and june 2006 to determine the frequency of gastrointestinal (gi) nematode infections of dogs in and around debre zeit, using qualitative and quantitative coprological (n = 100) and postmortem examinations (n = 20). by coproscopy 51% dogs were positive for different types of nematodal eggs, out of which 23.5% were with mixed infections. on necropsy 95% animals were found positive for adult parasites, of which 31.6% were showing more ... | 2007 | 17614203 |
prevalence of campylobacter and four endoparasites in dog populations associated with hearing dogs. | this study established the prevalence of four gastrointestinal parasites (isopora species, giardia species, uncinaria stenocephala, toxocara canis) and one bacterial infection (campylobacter jejuni/coli) in dogs associated with the charity hearing dogs for deaf people. | 2007 | 17617160 |
from the archives of the afip: pediatric orbit tumors and tumorlike lesions: neuroepithelial lesions of the ocular globe and optic nerve. | tumors and tumorlike lesions of the globe and optic nerve in children represent a different histologic spectrum than in adults; the imaging appearances of these lesions reflect their pathologic features. retinoblastoma is a tumor of infancy and the most common intraocular tumor in children. there are heritable and nonheritable forms. the most common clinical finding is leukocoria. the differential diagnoses of this sign include several nonneoplastic lesions: persistent hyperplastic primary vitre ... | 2007 | 17620473 |
[children enteroparasitosis in north east argentine urban area]. | the aim of the present investigation was to evaluate the importance of enteroparasitosis in a young urban population. the relationship between enteroparasitosis in this population and biological and environmental conditions was established for 113 infants between 0 and 14 years. serial stool samples were analyzed and graham tests were performed in each infant. the degree of nutrition of each infant was also assessed. environmental data were collected via semi-structured surveys. soil samples wer ... | 2007 | 17628910 |
[new data on anisakiasis]. | acute anisakiasis is generally due to the third-stage larvae of anisakis simplex, and occasionally to other anisakidae. human infection occurs through consumption of raw seafish, and especially herring, hake, black plaice and cod. patients sensitized by prior consumption of parasitized fish develop, within a few hours, violent abdominal pain and an allergic reaction. anisakis-induced urticaria is seen in about one in five cases. preventive measures have reduced the number of cases. in france for ... | 2007 | 17645107 |
seropositivity rates for bartonella henselae, toxocara canis and toxoplasma gondii in new zealand blood donors. | bartonella henselae, toxocara canis and toxoplasma gondii organisms can all cause vision-threatening posterior segment disease. diagnosis relies heavily on clinical findings, but detection of antibodies in the patient's serum may be helpful in some cases. the significance of a positive serology result depends on the seroprevalence in the general population. seroprevalence rates for these organisms vary widely around the world and this study aimed to determine the rates for a new zealand populati ... | 2007 | 17362453 |
catastrophic aortic thrombosis due to toxocara infection. | toxocariasis, a common helminthozoonosis with a worldwide prevalence, usually manifests as 'visceral larva migrans' (vlm). among its wide range of clinical presentations, large vessel thrombosis has never been described before. we report a case of aortic thrombosis caused by toxocara canis infection in a young male who was successfully treated with albendazole. | 2007 | 17366070 |
characterization of a toxocara canis species-specific excretory-secretory antigen (tces-57) and development of a double sandwich elisa for diagnosis of visceral larva migrans. | this study describes the isolation of a toxocara canis species-specific excretory-secretory (es) antigen and the development of an enzyme-linked immunosorbent assay (elisa) based on this antigen. analysis of the es antigens of t. canis, toxocara vitulorum, ascaris lumbricoides and necator americanus larval antigen was performed by sds-page followed by western blotting. a 57 kda t. canis-specific antibody fraction (tces-57) was identified by western blotting and labelling with anti-toxocara antib ... | 2007 | 17374974 |
migration behaviour and pathogenesis of five ascarid nematode species in the mongolian gerbil meriones unguiculatus. | to understand the characteristic features of the mongolian gerbil, meriones unguiculatus, as an animal model of ascarid infections, the migration behaviour and pathogenesis of larvae were investigated in experimentally infected gerbils. embryonated eggs from each of toxocara canis, baylisascaris procyonis, b. transfuga, ascaris suum, and a. lumbricoides were orally inoculated into gerbils and larvae were recovered from various organs at designated periods. in t. canis-infected gerbils, larvae we ... | 2007 | 17381866 |
utilizing a polymerase chain reaction method for the detection of toxocara canis and t. cati eggs in soil. | a polymerase chain reaction (pcr) technique has been used for the differentiation of t. canis and t. cati eggs isolated from soil and previously identified from microscopical observations. the method, using specific primers for the identification of the two toxocara species, was assessed in both the field and laboratory. successful results were obtained when only a single or large numbers of eggs were recovered from 40 g soil samples. the method is sensitive, allows analysis of material independ ... | 2007 | 17381871 |
impact of mk886 on eosinophil counts and phenotypic features in toxocariasis. | experimental toxocariasis was used as a model of eosinophil migration. mice inoculated with 200 toxocara canis eggs were treated with the leukotriene inhibitor mk886 (1 mg/kg/day). eosinophils were counted in peripheral blood (pb), peritoneal cavity (pc) and bronchoalveolar lavage fluid (balf) samples on post-infection days 3, 6, 12, 18, 24 and 36. eosinophil expression of mac-1 and vla-4 was analysed in pb and pc samples. we found that t. canis infection induced systemic eosinophilia from post- ... | 2007 | 17386025 |
influence of urbanization on the epidemiology of intestinal helminths of the red fox (vulpes vulpes) in geneva, switzerland. | dixenous helminths that depend on rodent intermediate hosts are supposed to be negatively affected by urbanization due to lower supply of rodents in urbanized environments. prevalence rates of dixenous, non-strictly monoxenous, and monoxenous helminths in 228 red foxes (vulpes vulpes) along a gradient of increasing urbanization were assessed by morphological parasite identification in the city of geneva, switzerland. multivariate analyses for the five most prevalent helminth species or genera re ... | 2007 | 17393184 |
ultrasonographic appearance of intestinal roundworms in a dog and a cat. | 2007 | 17693631 | |
toxocariasis of the cns simulating acute disseminated encephalomyelitis. | 2007 | 17709716 | |
oral treatment with a potential probiotic (enterococcus faecalis cect 7121) appears to reduce the parasite burden of mice infected with toxocara canis. | 2007 | 17716442 | |
[presentation of cerebral toxocariasis with mental confusion in an adult: case report and review of the literature]. | toxocariasis is usually responsible for visceral larva migrans syndroms. nervous system involvement is a rare complication. in this report, we describe one case of meningoencephalitis due to toxocara canis in a 73-year-old man presenting with mental confusion. the diagnosis of cerebral toxocariasis was confirmed by immunodiagnosis in both serum and cerebro-spinal fluid. cerebral toxocariasis may be suspected in patients presenting with some neurological patterns including: confusion, meningitis, ... | 2007 | 17727029 |
seroprevalence of zoonoses in a cree community (canada). | cree trappers and hunters are at risk for contracting infectious diseases conveyed by wildlife. we performed a study in a cree community (canada) to determine the seroprevalence of 8 zoonotic infections among hunters and trappers for evidence of exposure to trichinella sp., toxoplasma gondii, toxocara canis, echinococcus granulosus, leptospira sp., coxiella burnetii, francisella tularensis, and sin nombre virus. a total of 50 participants (28 women and 22 men) were included in this study. result ... | 2007 | 17878068 |
vasoproliferative tumors of the retina secondary to ocular toxocariasis. | 2007 | 17891207 | |
[a case of hepatic abscess caused by toxocara]. | toxocariasis is a helminozoonosis caused by the infection of a human host by the larva of toxocara canis and toxocara catis, which are common nematodes in dogs and cats, and occurs more frequently in school age children. toxocariasis shows variable clinical manifestations including hepatomegaly, bronchial asthma, uveitis, central nervous system symptoms with peripheral eosinophilia and an increased total serum ige level. however a hepatic abscess caused by toxocara infection in adults is rare. w ... | 2007 | 17898557 |
visceral larva migrans presenting as multiple intracranial and intraspinal abscesses. | involvement of nervous system by toxocariasis is rare and can produce a spectrum of pathology that includes eosinophillic meningoencephalitis, meningomyelitis, space occupying lesions, vasculitis causing seizures or behavioral abnormalities posing diagnostic dilemmas. we describe a 38-year-old man who presented with multiple intracranial and intramedullary abscesses caused by visceral larva migrans. neurohelminthiasis as a cause of multiple abscesses, though rare, should be entertained as a diff ... | 2007 | 17899691 |
changes to plasminogen activators and matrix metalloproteinase-9 in dogs with toxocarosis. | the relationship between proteolytic enzymes and hematological response to infection was studied in five 1-month-old dogs inoculated experimentally with 2000 eggs of toxocara canis. moderate leukocytosis and marked eosinophilia occurred 14 days post-infection with t. canis. plasminogen activators (pas) and matrix metalloproteinase-9 (mmp-9) activity in serum was significantly different in dogs infected with t. canis, compared with controls. urokinase-type pa (upa) activity was positively correla ... | 2007 | 17913363 |
evaluation of follow-up of therapy with fenbendazole incorporated into stabilized liposomes and immunomodulator glucan in mice infected with toxocara canis larvae. | anthelmintic activity of benzimidazole carbamate anthelmintics is low against dormant toxocara canis larvae during late infections in paratenic hosts. the present study was conducted to examine the efficacy of pure fenbendazole, or drug incorporated into sterically stabilized liposomes (sl-fbz) administered to t. canis-infected mice alone and after its co-administration with the immunomodulator (1-->3)-beta-d-glucan against larvae localized in muscles and brains. therapy with either drug forms ( ... | 2007 | 17915186 |
[the occurrence of gastrointestinal cestode and nematode infections in stray dogs in afyonkarahisar and eskisehir provinces]. | this study was carried out to determine the prevalence of cestode and nematode infections in stray dogs in afyonkarahisar and eskisehir provinces. a total of 287 dogs (n=150 from afyonkarahisar and n=137 from eskisehir) of different ages and sexes living in animal shelters were used in this study. after the coprological examination, dogs were found to be infected with various gastrointestinal cestode and nematode species. it was found that rates of infection were 46% (69 out of 150) in afyonkara ... | 2007 | 17918061 |
survey of intestinal parasites in stray dogs in the madrid area and comparison of the efficacy of three anthelmintics in naturally infected dogs. | using routine coprological methods, 1161 faecal samples from animal shelters located in madrid (spain) were analysed, showing a 28% prevalence for different intestinal parasites: giardia duodenalis (7%), cystoisopora spp. (3.8%), toxocara canis (7.8%), toxascaris leonina (6.3%), ancylostomidae (4%), trichuris vulpis (3.3%), taenidae (2.9%) and dipylidium caninum (0.9%). the therapeutic efficacies of mebendazole at a dose of 22 mg/kg once daily for 3 days, fenbendazole at a dose of 50 mg/kg once ... | 2007 | 16915389 |
estimation of canine intestinal parasites in córdoba (spain) and their risk to public health. | the prevalence of gastrointestinal parasites in dogs was studied in the province of córdoba (southern spain), with special attention to those parasites that can be transmitted to man. the experiment was completed with the examination of soil samples from public parks and city gardens. the study was carried out over a population of 1800 animals entered in the control animal centre (ceca) by coprological methods, and within this group, 300 dogs were sacrificed and necropsied. the prevalence of any ... | 2007 | 16971046 |
o-methylated glycans from toxocara are specific targets for antibody binding in human and animal infections. | the parasitic helminth toxocara canis is a widely distributed nematode of mammals. larval parasites, which infect a wide range of hosts including mice and humans, export glycosylated macromolecules bearing novel methylated oligosaccharide structures, similar to the mammalian blood group antigen h but bearing one or two o-methylated substitutions on the terminal fucose and subterminal galactose residues. we have studied the reactivity of synthetic forms of these glycans to parasite-specific antib ... | 2007 | 17087964 |
protein profile analysis from advanced third-stage larvae (advl3) and adult worms of gnathostoma binucleatum (nematoda: spirurida). | proteins from crude extracts of advanced third-stage larvae and adult gnathostoma binucleatum nematode worms showed protein profiles in sds-page analysis similar to echinococcus granulosus, trichinella spiralis, dipylidium caninum, ancylostoma caninum, ascaris lumbricoides and toxocara canis. the immunoblot analysis of the human serum infected or suspected to be infected with g. binucleatum using the total larvae extract recognized the 40, 60, 80 and 115 kda proteins and using the total adult wo ... | 2007 | 17096141 |
toxocara canis: effect of inoculum size on pulmonary pathology and cytokine expression in balb/c mice. | infection of mice with toxocara canis results in pulmonary inflammation and the induction of a th2 type of immune response. the aim of this study was to determine whether the effect of infection with this nematode depends on the inoculum size. results indicate that mice infected with either a high or a low inoculum size showed, in a dose-dependent manner, pulmonary inflammation with eosinophil infiltration, increased levels of total ige, and toxocara-specific igg1 that persisted up to 60 days p. ... | 2007 | 16908022 |
the prevalence of intestinal parasites in dogs from prague, rural areas, and shelters of the czech republic. | the prevalence of intestinal parasites was evaluated by examination of dog faecal samples in the prague city centre, agricultural areas, and two shelters. the overall prevalence of parasites (i.e., protozoa and helminths, mentioned below) in prague was 17.6%. toxocara canis was the most common parasite, and was recovered from 6.2% of dogs, followed by cystoisospora spp. (2.4%), cryptosporidium spp. (1.4%), trichuris sp. (1.1%), taenia-type (1.0%), giardia spp. (0.1%), toxascaris sp. (0.9%), dipy ... | 2007 | 17169492 |
field evaluation of the efficacy and the safety of a combination of oxantel/pyrantel/praziquantel in the treatment of naturally acquired gastrointestinal nematode and/or cestode infestations in dogs in europe. | in five multicentre field trials, the efficacy and safety of a combination of oxantel/pyrantel/praziquantel (dolpac), vetoquinol sa) in the treatment of naturally acquired gastrointestinal nematode and/or cestode infestation in dogs was evaluated in northern and southern europe. forty-eight investigators from france, belgium, germany, italy and spain enrolled 329 dogs to be treated with the tested combination; 235 of these dogs complied with the inclusion criteria of the protocol and had a teste ... | 2007 | 17184919 |
evaluation of immunodiagnostics for toxocarosis in experimental porcine cysticercosis. | we assessed whether immunodiagnostic tests for cysticercosis can cross-react with the currently available immunodiagnostic tests for toxocara canis in an established animal model for cysticercosis infection in pigs, known host for toxocara. we examined by tes-enzyme-linked immunosorbent test and immunoblot assay for toxocarosis and cysticercosis the baseline and final follow-up sera of 10 pigs, before and after (3 months) infection with taenia solium. after successful cysticercosis infection, th ... | 2007 | 17207154 |
[ocular toxocariasis. from biology to therapy]. | ocular toxocariasis represents an organ manifestation of the systemic infection with the nematode larva toxocara canis. the infection can provoke very different changes in the eye. especially posterior uveitis, vitreous body infiltrates, epiretinal membranes and suberetinal granulomas can occur. the diagnosis of these changes can be difficult due to the variety of the symptoms and on the other side by the absence of characteristic specific changes. moreover unclear findings can occur when only s ... | 2007 | 17219180 |
a rare case of toxocara canis cerebral vasculitis. | 2007 | 17222098 | |
epilepsy and seropositivity rates of toxocara canis and toxoplasma gondii. | increased seropositivity for toxoplasma gondii and toxocara canis have been observed in epileptic patients. our aim is to determine whether there is any relationship between these agents and epilepsy in our cryptogenic epilepsy group. | 2007 | 17239629 |
seasonal fluctuations in prevalence of dog intestinal parasites in public squares of mar del plata city, argentina and its risk for humans. | the aim of this work is to analyze whether there is a seasonal prevalence of parasites in dog feces from public squares in mar del plata city, argentina, and to evaluate the climatic conditions that promote the development of parasites and allow the transmission to people. the study was performed in 21 squares from june 2001 to may 2002. samples were processed by the willis technique. differences in prevalence of parasites were examined for significance by the chi-square test. climatic data were ... | 2007 | 18390156 |
[visceral and cutaneous larva migrans]. | the syndrome of visceral larva migrans was described for the first time in 1952 by beaver. he demonstrated that the presence of nematodes larvae, particularly in the liver, were those of toxocara canis and t. cati. baylisascaris procyonis, the common racoon ascarid in the u.s.a. can also cause serious diseases in human. digestive and respiratory clinical symptoms are usually moderate, however severe disease resulting from invasion of the myocardium or the brain has been reported. a blood hypereo ... | 2007 | 18326429 |
prevalence of echinococcosis in street dogs in tripole district, libya. | cystic echinococcosis due to e. granulosus is a serious public health and livestock economy problem in libya. kato thick smear examination of 50 street dogs stools showed that they had echinococcus granulosus (58%), taenia spp. (14%), diplydium caninum (16%), toxocara canis (121%) and 20% were parasite-free. the stool examination using kato thick smear was more sensitive and more specific that the indirect haemaggutination test. the results were discussed with general review of the disease in li ... | 2007 | 18383781 |
seroprevalence of toxocariasis in children aged 1-9 years in western islamic republic of iran, 2003. | we determined the seroprevalence of toxocara canis infection in 544 children under 10 years randomly selected from urban and rural areas of hamadan. an enzyme-linked immunosorbent assay was used for detection of antibodies to t. canis excretion-secretion antigens. using a questionnaire, epidemiological factors associated with infection were examined, including age, sex, residence. antibodies to t. canis were detected in 29 children (5.3%) and 19 children (3.5%) were categorized as borderline pos ... | 2007 | 18290400 |
helminth infections in faecal samples of wolves canis lupus l. from the western beskidy mountains in southern poland. | eighty-nine samples of grey wolf (canis lupus l.) faeces were collected between 2002 and 2004 from two areas in the western beskidy mts (south poland). helminth eggs were observed in 56.2% of faeces examined. these included: alaria alata (2.2%), taeniid eggs (11.2%), toxocara canis (5.6%), toxascaris leonina (1.1%), eucoleus aerophilus (14.6%), ancylostoma caninum (12.3%), uncinaria stenocephala (37%) and unidentified roundworm eggs of the family strongyloididae (1.1%). eucoleus aerophilus is re ... | 2007 | 18251025 |
frequency of toxocara infection in children attended by the health public service of maringá, south brazil. | the lack of specific laboratorial diagnosis methods and precise symptoms makes the toxocariasis a neglected disease in public health services. this study aims to determine the frequency of toxocara spp. infection in children attended by the health public service of hospital municipal de maringá, south brazil. to evaluate the association of epidemiological and clinical data, an observational and cross-section study was carried out. from 14,690 attended children/year aged from seven month to 12 ye ... | 2007 | 18157398 |
serodiagnosis of toxocara antibodies among infants and pregnant women suspected of ocular or visceral toxocariasis using two types elisa antigens. | the diagnosis of toxocariasis heavily depends on immunological tests because the number of parasites is usually few in infected tissues, unless they migrate into an organ such as eye. in general, patients with ocular toxocariasis have serum anti-t canis antibody titres that are significantly lower than those with visceral toxocariasis. | 2006 | 18685178 |
population dynamics and epidemiology of toxocara canis in danish red foxes. | toxocara canis, an intestinal helminth of canids with zoonotic potential, was found in 618 (59%) of 1,040 red foxes (vulpes vulpes) collected from all danish provinces (1997-2002). the prevalence and average worm burden were significantly higher for cubs than older foxes and in males than in females. a multiple logistic regression demonstrated that the prevalence was influenced significantly by sex and age of foxes in addition to location, season, and year of collection. the highest prevalence a ... | 2006 | 17304794 |
frequency of soil contamination by toxocara canis eggs in the south region of são paulo municipality (sp, brazil) in a 18 month period. | soil contamination by embryonic eggs of toxocara canis is the main source of human infection by this ascarid larvae resulting, sometimes, in the occurrence of visceral larva migrans syndrome. the objective of the present research is to determine the frequency of t. canis eggs in soil samples monthly collected in nine public places, located at the south region of são paulo municipality in a 18-month period, from february 2004 to july 2005. the soil samples collected were treated with a 30% antifo ... | 2006 | 17221127 |
[a case of toxocariasis with eosinophilic pleural effusion]. | a 76-year-old man admitted for general malaise with fever was found in clinical examination on admission to have eosinophilic pleural effusion, peripheral eosinophilia, and a slightly elevated inflammatory reaction. immunological examination, including microplate elisa, showed a high titer of specific antibody against toxocara canis in both the serum and pleural effusion. we started treatment using albendazole, and found inflammatory findings and serum ige were ameliorated. parasitic disease is ... | 2006 | 17176861 |
eosinophil cationic protein, specific ige and igg4 in human toxocariasis. | among 67 french patients presenting a toxocaral infection, various demographic, environmental, clinical and laboratory parameters (blood eosinophil count, eosinophil cationic protein (ecp), serum total ige, specific ige against common inhalant allergens, specific ige and igg4 against toxocara excretory-secretory antigens) were investigated. correlation studies and logistic regression analyses were conducted, testing elevated levels of ecp, specific anti-toxocara ige or igg4 as outcome variables ... | 2006 | 17125552 |
visceral larva migrans granulomas in liver and central nervous system of children who died of bacterial or viral meningitis. | 2006 | 17140159 | |
hepatic visceral larva migrans of toxocara canis: ct and sonographic findings. | the aim of this study was to describe the ct and sonographic findings of hepatic visceral larva migrans of toxocara canis. | 2006 | 17114516 |