Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| nonpolar components of the latex of euphorbia peplus. | the less polar fractions of the latex of euphorbia peplus were found to contain obtusifoliol, cycloartenol, 24-methylenecycloartanol, lanosterol, and 24-methylenelanosterol in the free and esterified triterpene alcohol fractions; 9-cis-tricosene as the major component of the hydrocarbon fraction; and a new acyclic triterpene alcohol named peplusol (1). the structure of 1 was determined as the r-isomer of (all-e)-2-(5,9-dimethyl-1-methylene-4,8-decadienyl)-5,9, 13-trimethyl-4,8,12-tetradecatrien- ... | 2000 | 10691725 |
| inhibitory effect of euphol, a triterpene alcohol from the roots of euphorbia kansui, on tumour promotion by 12-o-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. | the anti-inflammatory activity of euphol, twelve other triterpene alcohols and sitosterol-beta-d-glucopyranoside, isolated from the dichloromethane extract of the roots of euphorbia kansui, has been evaluated in mice with inflammation induced by 12-o-tetradecanoylphorbol-13-acetate (tpa). tpa (1.7 nmol; 1.0 microg/ear) was dissolved in acetone and 10 microl delivered to the inner and outer surfaces of the right ear of icr mice. a triterpene alcohol, sterol glucoside or vehicle (20 microl; chloro ... | 2000 | 10716613 |
| polycyclic diterpenoids from euphorbia characias. | in addition to widespread flavonoids, a collection of euphorbia characias from sardinia afforded 13 oxygenated diterpenoids of the atisane, abietane, pimarane, and kaurane type. four of these compounds (1, 3a, 7a,b) are new. the accumulation of substantial amounts of biologically active diterpenoids of limited availability, like ent-atisanes endowed with anti-hiv activity and ent-abietanolides active on the central nervous system, makes e. characias an interesting source of lead compounds for bi ... | 2000 | 10727809 |
| cucumisin-like protease from the latex of euphorbia supina. | a protease has been purified from the latex of euphorbia supina rafin by two steps of chromatography. the mr was estimated by sds-page to be 80 kda. its activity was inhibited strongly by diisopropyl fluorophosphate, but not by edta, pepstatin, or cysteine protease inhibitors, indicating that the enzyme is a serine protease. the specificity of the protease is broad, but the preferential cleavage sites were c-terminal sites of hydrophobic amino acid residues. the n-terminal sequence of the first ... | 2000 | 10746875 |
| molluscicidal activity of some saudi arabian euphorbiales against the snail biomphalaria pfeifferi. | the comparative susceptibility of the snail vector of intestinal schistosomiasis, biomphalaria pfeifferi to the action of extracts from saudi arabian euphorbiales has been determined. methanol and chloroform extracts of the plants tested (jatropha glauca, euphorbia helioscopia and euphorbia schimperiana) were the most promising from the molluscicidal point of view with ld(50) values in the range 10-100 ppm. | 2000 | 10771201 |
| antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in kinshasa, congo. | three major extracts from some traditional preparations, based on medicinal plants, used as antidiarrhoeal agents were investigated for their putative antiamoebic and spasmolytic activities in vitro. results indicated that both biological activities are concentrated in the polyphenolic fraction, and not in the saponin or alkaloid containing fractions. the most active polyphenolic extracts were those from euphorbia hirta whole plant, leaves of alchornea cordifolia, crossopteryx febrifuga, nauclea ... | 2000 | 10782488 |
| a phylogenetic study of tribe euphorbieae (euphorbiaceae). | a phylogenetic investigation of a monophyletic lineage of spurge plants, tribe euphorbieae, was conducted to elucidate evolutionary relationships, to clarify biogeographic patterns, and to reexamine the previous classification of euphorbieae. cladistic analyses of the 52 morphological characters of 61 species resulted in 2922 equally most parsimonious trees of 193 steps with a consistency index of 0.34. the strict consensus tree indicates genus anthostema of subtribe anthosteminae as a likely si ... | 2000 | 10817978 |
| microstructure of purified rubber particles. | purified rubber particles from hevea brasiliensis (brazilian rubber tree), parthenium argentatum (guayule), ficus elastica (indian rubber tree), and euphorbia lactiflua were examined and compared using conventional scanning electron microscopy (sem), field-emission sem, cryo-sem, and transmission electron microscopy (tem). rubber particles of all four species were spherical; they varied in size and had a uniform homogeneous material, the rubber core, surrounded by a contiguous monolayer (half-un ... | 2000 | 10817979 |
| constituents and bioactivity of the tubers of euphorbia sessiliflora. | the diterpene ent-12-hydroxy-12[r]-abieta-8(14),13(15)-dien-16,12-olide was isolated from the tubers of euphorbia sessiliflora roxb., together with four known ent-abietadienolides, four known cycloartane triterpenes and ellagic acid-beta-d-glucopyranoside. two of these metabolates displayed moderate antibacterial activities. | 2000 | 10820809 |
| diterpenoids from euphorbia peplus. | from a pro-inflammatory active extract of euphorbia peplus, two new diterpene polyesters based on the pepluane and jatrophane skeletons were isolated, together with four known ingenane and jatrophane diterpenes. the structures were determined on the basis of extensive nmr studies. ingenol 3-angelate, which was obtained for the first time from this plant, is an irritant toxin with high activity. | 2000 | 10821064 |
| sequence analysis and genome organisation of poinsettia mosaic virus (pnmv) reveal closer relationship to marafiviruses than to tymoviruses. | sequence comparison and genome organisation of poinsettia mosaic virus (pnmv), a putative member of the tymoviruses, revealed a closer relationship to marafiviruses. the complete nucleotide sequence of pnmv was determined. the 6099-nt rna genome encodes a putative 221-kda polyprotein that lacks a stop codon between the replicase and the coat protein genes, as in most tymovirus rnas. the genomic rna has a poly(a) tail at its 3'-terminus in contrast to the trna-like structure found in the rna of m ... | 2000 | 10860883 |
| an economic comparison of biological and conventional control strategies for whiteflies (homoptera: aleyrodidae) in greenhouse poinsettias. | the objective of this study was to evaluate the costs of biologically controlling infestations of silverleaf whitefly, bemisia argentifolii bellows & perring, in new england greenhouse operations on poinsettia, euphorbia pulcherrima wild, ex koltz, using the parasitic wasp encarsia formosa gahan (nile delta strain). partial budget analysis was used to compare costs for conventional verses biological control regimens. four alternative whitefly control budgets are developed; two conventional chemi ... | 2000 | 10902307 |
| imidacloprid applications by subirrigation for control of silverleaf whitefly (homoptera: aleyrodidae) on poinsettia. | the objective of this study was to determine whether silverleaf whiteflies, bemisia argentifolii bellows & perring, on poinsettia, euphorbia pulcherrima willdenow ex klotsch, can be controlled with imidacloprid applied by subirrigation. different amounts of imidacloprid uptake by the growing medium were obtained by not watering the subirrigated plants for 0, 1, 2, or 4 d before the imidacloprid application. these treatments resulted in absorption of 12-175 ml of imidacloprid solution by the grow ... | 2000 | 10902335 |
| toxicity of euphorbia milii latex and niclosamide to snails and nontarget aquatic species. | the toxicity of euphorbia milii molluscicidal latex and niclosamide (ncl) to target snails (biomphalaria glabrata and biomphalaria tenagophila) and nontarget aquatic organisms is evaluated. planorbidae snails were killed by very low concentrations of lyophilized latex (48-h lc(50), mg/l: b. glabrata, 0.12; b. tenagophila, 0.09; helisoma duryi, 0.10). latex was less toxic (48-h lc(50) or ec(50), mg/l) to oligochaeta (tubifex tubifex, 0.31), planktonic crustacea (daphnia similis, 0.38; c. dubia, 1 ... | 2000 | 10903832 |
| the laticifer system of chamaesyce thymifolia: a closed host environment for plant trypanosomatids. | specimens of chamaesyce thymifolia (euphorbiaceae) infected and uninfected by phytomonas sp., a parasite of the trypanosomatidae family, were anatomically and ultrastructurally analyzed with special emphasis on the laticifer system. c. thymifolia presents branched non-articulated laticifers and was heavily infected by phytomonas sp. in all collection sites. infection was often observed in the initial stages inside the vacuole, when the latex particles could be seen. in intermediary stages of lat ... | 2000 | 10979610 |
| ultrastructural analysis of phytomonas species from euphorbia pinea reveals trans-cytoplasmic filaments 10 nm in diameter. | phytomonas sp. derived from euphorbia pinea are digenetic plant trypanosomes that are transmitted by the squashbug stenocephalus agilis and exist exclusively as promastigotes. the stable sub-pellicular microtubular array, the flagellar axoneme and the paraflagellar rod represent the major cytoskeletal components common to all trypanosomes. the work described in this paper examines in detail the ultrastructural morphology of the organism and highlights a number of novel structural features, and i ... | 2000 | 11068818 |
| anti-inflammatory activity of the hydrosoluble fraction of euphorbia royleana latex. | the hydrosoluble fraction of euphorbia royleana latex (aer), administered by gavage at doses of 50-200 mg/kg, showed dose-dependent anti-inflammatory and anti-arthritic effects in different acute and chronic test models in rats and mice. it reduced the exudate volume and the migration of leukocytes and showed a poor inhibitory effect on the granuloma formation induced by cotton pellets, while it had a low ulcerogenic score. the oral ld(50) was more than 1500 mg/kg in both rats and mice. | 2000 | 11077172 |
| an expeditious procedure for the isolation of ingenol from the seeds of euphorbia lathyris | a short and practical process for the isolation of ingenol (1a) from an agricultural commodity (the seeds of euphorbia lathyris) is described. macrocyclic diterpene esters are obtained as byproducts, and the esterification pattern of the euphorbia factors l2 (3), l3 (4a), and l8 (4b) was established by 2d nmr measurements. full spectroscopic data for these compounds are reported. | 1999 | 9917286 |
| isolation and structure revision of pepluane diterpenoids from euphorbia peplus | a new pepluane diterpene polyester (2) was isolated from a ch2cl2 extract of the whole, undried plant of euphorbia peplus, together with the known compound 1. the structures were established by high-field spectroscopic methods, including 2d nmr techniques, and by x-ray crystallography, and the stereostructure of the first member of the pepluane diterpenoids (1) was revised. | 1999 | 9917293 |
| isoterracinolides a and b, novel bishomoditerpene lactones from euphorbia terracina | an extract of euphorbia terracina l. has yielded six acylated polyhydroxy terpenoid lactones (1-6), which all display the c22 17-ethyljatrophane carbon framework. four of these (1-4) are delta lactones belonging to the previously described terracinolide type, and two of them (2, 3) are new. two further new compounds have been named isoterracinolides a (5) and b (6) and exhibit an eight-membered lactone ring. another isolated new compound is the jolkinolide-type, ent-abietane gamma lactone (7). | 1999 | 9917294 |
| a novel lathyrane diterpenoid from the roots of euphorbia lathyris | a new lathyrane diterpene (1) has been isolated and characterized from a ch2cl2 extract of the roots of euphorbia lathyris. detailed spectral analysis revealed that the structure of 1, including relative stereochemistry, is that of a diester of a hitherto unknown, polyfunctional diterpene parent alcohol. | 1999 | 9917314 |
| a search for anti-viral properties in panamanian medicinal plants. the effects on hiv and its essential enzymes. | aqueous and methanolic extracts of 39 panamanian medicinal plants were tested for anti-human immunodeficiency virus (hiv) effects. the extracts were tested for the inhibition of hiv-induced cytopathic effects in cultured cells, hiv-reverse transcriptase (rt) and hiv-protease (pr) enzymes. the water extract of the branches of jatropha curcas (euphorbiaceae) inhibited strongly the hiv-induced cytopathic effects with low cytotoxicity. on the other hand, the water extracts of the whole plant of cham ... | 1999 | 10075118 |
| inhibitory effects of sudanese plant extracts on hiv-1 replication and hiv-1 protease. | forty-eight methanol and aqueous extracts from sudanese plants were screened for their inhibitory activity on viral replication. nineteen extracts showed inhibitory effects on hiv-induced cytopathic effects (cpe) on mt-4 cells. the extracts were further screened against hiv-1 protease (pr) using an hplc assay method. of the tested extracts, the methanol extracts of acacia nilotica (bark and pods), euphorbia granulata (leaves), maytenus senegalensis (stem-bark) and aqueous extracts of a. nilotica ... | 1999 | 10189947 |
| biological screening of traditional preparations from some medicinal plants used as antidiarrhoeal in kinshasa, congo. | forty six aqueous extracts from 38 medicinal plant species belonging to different families were selected on the basis of their traditional medicinal use as antidiarrhoeic agents. they were submitted in a broad biological screening including antibacterial, antiamoebic and antispasmodic activities. the results of the testing have indicated that 37 extracts (80.43%), 33 (71.74%) and 32 (69.54%) exhibited some level of antibacterial, antiamoebic and antispasmodic activity respectively. only 8 plant ... | 1999 | 10228613 |
| euphorbia hirta leaf extracts increase urine output and electrolytes in rats. | euphorbia hirta is locally used in africa and australia to treat numerous diseases, including hypertension and edema. the diuretic effect of the e. hirta leaf extracts were assessed in rats using acetazolamide and furosemide as standard diuretic drugs. the water and ethanol extracts (50 and 100 mg/kg) of the plant produced time-dependent increase in urine output. electrolyte excretion was also significantly affected by the plant extracts. the water extract increased the urine excretion of na+, k ... | 1999 | 10350369 |
| tumor promoting diterpenes from euphorbia leuconeura l. | diterpene esters of the phorbol and ingenol types are known to be highly active tumor promoting agents that typically occur in members of the euphorbiaceae. in the present work, euphorbia leuconeura, a rare indoor plant, is analyzed for its tumor promoting potential. latex as well as total leaf extracts exhibited epstein-barr-virus (ebv) inducing activity comparable to 12-o-tetradecanoyl-phorbol-13-o-acetate, a well known tumor promoter. the activity of individual fractions correlated with their ... | 1999 | 10365450 |
| [terpenoids and steroids from several euphorbiaceae and pinaceae plants]. | during the course of a search for biologically active constituents from unexamined plant sources, several biogenetically interesting new di- and tri-terpenes and steroids were isolated from several weeds and shrubs of euphorbiaceae and the bark, leaves and cones of several pinaceae trees which had been treated as wastes in the forestry industry. euphorbia supina contained 3,4-seco-5 alpha- and 5 beta-adian-4(23)-ene-3,5-diols and related oxides, oxygenated fern-8-en-3 beta-ols named supinenolone ... | 1999 | 10375995 |
| jatrophane diterpenoids from euphorbia peplus. | from the pro-inflammatory active extract of euphorbia peplus, a new diterpene polyester (1) based on the jatrophane skeleton was isolated together with the known compounds 2-5. the irritant activities of some jatrophane diterpenes (2, 3 and 6-9) were also investigated: only compound 2 was found to exert a weak pro-inflammatory activity on mouse ear. | 1999 | 10392470 |
| new diterpenoids from euphorbia teheranica | two novel pentacyclic diterpenoid esters of the cyclomyrsinane type (1, 2), and one tetracyclic diterpenoid ester of the myrsinane type (3) were isolated from the aerial parts of the plant euphorbia teheranica. the structures of the novel compounds were determined by spectral data interpretation. | 1999 | 10425130 |
| piceatannol, a stilbene phytochemical, inhibits mitochondrial f0f1-atpase activity by targeting the f1 complex. | piceatannol is a stilbene phytochemical from the seeds of euphorbia lagascae, previously identified as an antileukemic principle. piceatannol is considered an inhibitor of several tyrosine kinases. we recently reported that resveratrol, another stilbene phytoalexin from grape seeds, was an inhibitor of atp synthase. here, we demonstrated that piceatannol potently inhibited the rat brain mitochondrial f0f1-atpase activity in both solubilized and submitochondrial preparations (ic50 of 8-9 microm), ... | 1999 | 10425214 |
| the influence of environmental factors on the molluscicidal activity of euphorbia milii latex. | the present study was undertaken to investigate the influence of biotic (snail size and presence of food during the test) and abiotic factors (temperature, water hardness and concentration of organic materials) on the molluscicidal activity of euphorbia milii latex. bioassays were conducted with b. glabrata (10 snails per concentration) and snail lethality was evaluated after 24 hr and 48 hr of exposure to lyophilized latex solutions. neither the degree of water hardness, nor the presence of foo ... | 1999 | 10507917 |
| [dermatitis and conjunctivitis after contact with euphorbia myrsinites (wolf's milk extract)--a case report]. | fresh sap of euphorbiaceae leads to a toxic burn of the skin and the eyes. since years the sap of euphorbiaceae has been used in the treatment of different kinds of verrucas. | 1999 | 10528288 |
| diterpenoids from euphorbia pithyusa subsp. cupanii | the aerial parts of euphorbia pithyusa subsp. cupanii collected in sardinia afforded eleven novel diterpenoids belonging to the lathyrane (1a), premyrsinane (4a-g), and tigliane (5a-c) types. compounds 4a-g and 5a are esters of two new parent alcohols, named premyrsinol and 4,12,20-trideoxyphorbol, respectively. structures were elucidated by spectroscopic and chemical methods. puzzling differences between the nmr data of lathyrol (1c) and its esters were rationalized in terms of flipping of the ... | 1999 | 10543901 |
| rubber particles from four different species, examined by transmission electron microscopy and electron-paramagnetic-resonance spin labeling, are found to consist of a homogeneous rubber core enclosed by a contiguous, monolayer biomembrane | the physical characteristics of rubber particles from the four rubber (cis-1,4-polyisoprene) producing species euphorbia lactiflua phil., ficus elastica roxb., hevea brasiliensis mull. arg., and parthenium argentatum gray, were investigated using transmission electron microscopy (tem) and electron-paramagnetic-resonance (epr) spin labeling spectroscopy. transmission electron microscopy showed the rubber particles to be composed of a spherical, homogeneous, core of rubber enclosed by a contiguous ... | 1999 | 10592036 |
| antimalarial activity of 20 crude extracts from nine african medicinal plants used in kinshasa, congo. | twenty extracts including ten etoh and ten ch2cl2 from different parts of nine african medicinal plants used in congolese traditional medicine for the treatment of malaria, were submitted to a pharmacological test in order to evaluate their effect on p. falciparum growth in vitro. of these plant species, 14 (70%) extracts including etoh and ch2cl2 from cassia occidentalis leaves, cryptolepis sanguinolenta root bark, euphorbia hirta whole plant, garcinia kola stem bark and seeds, morinda lucida l ... | 1999 | 10624878 |
| [antitumor activity of the root of euphorbia helioscopic in vitro]. | antitumor activity of the aquatic extract the root of euphorbia helioscopia l (ewe) in vitro were studied. viable cells count, mtt staining and colonal formation assays of three kinds of cancer cells were used to assess the antitumor activity. determined by viable cells count, the ic50 values of ewe against 7721, hela, mkn-45 cells were 1.26, 1.98, 1.72 mg/ml respectively (72 h). determined mtt staining, the ic50 values ewe against 7721, hela, mkn-45 cells were 1.43, 1.67, 0.97 mg/ml. determined ... | 1999 | 12575050 |
| [pharmacognostical studies on the roots of euphorbia soongarica]. | morphological and microscopical characters of the roots of euphorbia soongarica boiss. used as one of the origins of the chinese medicine daji in xinjiang autonomous region of china were described and illustrated with line drawings. tlc and hplc analysis of the above drug was also undertaken. these studies provide referencial informations for clinics, quality control, development and identification of this crude drug. | 1999 | 12575074 |
| [pharmacognostical studies on the roots of euphorbia prolifera]. | morphological and histological characters of the roots of euphorbia prolifera buch.-han., a traditional chinese medicine, were described and illustrated with line drawings. tlc analysis of the above drug was also undertaken. these studies provide referencial informations for clinics, quality control, development and identification of this crude drug. | 1999 | 12575093 |
| [studies on chemical constituents of euphorbia ebracteolata ilayata]. | to search for the effective anti-epilepsiy components from the chinese folk drug langdu, the root of euphorbia ebracteolata. | 1999 | 12205948 |
| triterpenoids and a diterpene from euphorbia iberica. | from the aerial parts of euphorbia iberica, an ingenane diterpene ester, ingenol 20-eicosanoate, and three ursanetype triterpenoids, 3beta-acetoxy-urs-12-ene-1beta,11alpha-diol, 3beta-( e)-coumaroyloxy-urs-12-ene, and 3beta-( z)-coumaroyloxy-urs-12-ene have been isolated together with known cylcoartane-type triterpenes, a flavone, and coumarins. the first four compounds are new and their structures were determined by spectroscopic methods. | 1999 | 17260273 |
| a new lanostane-type triterpenoid from chamaesyce prostrata. | a new triterpenoid, namely, lanost-25-en-3-beta-ol, and two known flavonoids (kaempferol-3,6-dimethyl ether and kaempferol 7- o-glucoside) were isolated from the aerial parts of chamaesyce prostrate (euphorbiaceae). the structure of the new compound was established based on spectral evidences. | 1999 | 17260274 |
| three tricyclic diterpenoids from euphorbia decipiens. | three new diterpene esters with a tricyclic lathyraneor myrsinol-type skeleton have been isolated from euphorbia decipiens boiss & buhse. the structures have been elucidated by different spectroscopic methods including 1d and 2d nmr spectroscopy techniques. | 1998 | 17253318 |
| fungal pathogens of euphorbia heterophylla and e. hirta in brazil and their potential as weed biocontrol agents. | a two-year survey of the fungi associated with two important congeneric pantropical weeds, euphorbia heterophylla and e. hirta, was conducted in part of their native range in southern brazil. sampling was concentrated mainly in rio de janeiro state and ten species were identified as pathogens of these weeds. two taxa, botrytis ricini and uromyces euphorbiae, were common to both weed hosts. alternaria euphorbiicola, bipolaris euphorbiae, melampsora sp., oidium sp. and sphaceloma poinsettiae were ... | 1998 | 16284862 |
| [studies on diterpenoids from the roots of euphorbia ebracteolata]. | euphorbia ebractolata has been used as insecticide and tuberculocide. four crystalline compounds were isolated from the root of this plant. they were characterized by their physico-chemical properties and spectral data as: 3-acety alpha-amyrin (i), jolkinolide b (ii), ebracteolatanolide a (iii) and ebracteolatanolide b (iv). i and ii were isolated for the first time from e. ebracteolata hayata. iii and iv are new compounds. | 1998 | 11938948 |
| euphorbia hirta leaves and musa sapientum fruits in culture media for fungi. | two plant products, euphorbia hirta leaves and fruits of musa sapientum, were evaluated as principal ingredients for selective cultivation of fungi. sapientum glucose agar supported the growth of both dermatophytic, yeast-like, and saprophytic fungi; growth on this medium compared favourably with growth on sabouraud glucose agar, a standard mycological medium. sporulation and pigment formation were stronger on sapientum glucose agar than on sabouraud glucose agar, although fungal growth on the l ... | 1998 | 9919898 |
| effects of euphorbia milii latex on schistosoma mansoni eggs, miracidia and cercariae. | 1998 | 9921358 | |
| cytotoxicity and antiviral activity of the compounds from euphorbia kansui. | eleven compounds including four triterpenes, one sterol, and six diterpenes from e kansui had been assayed for their cytotoxicity and activiral activity. the relations between structures and bioactivities have also been noted. | 1998 | 9933994 |
| recent advances on bioactive natural products from chinese medicinal plants. | china has accumulated a rich body of empirical knowledge of the use of medicinal plants for the treatment of various diseases throughout its long history. chemical studies on chinese medicinal plants provide a valuable material base for the discovery and development of new drugs of natural origin. in this article recent chemical work on various chinese medicinal plants is reviewed, including mussaenda pubescens (rubiaceae), isatis indigotica (cruciferae), euphorbia fischeriana, and e. ebracteola ... | 1998 | 9828038 |
| botanical briefs: leafy spurge--euphorbia esula l. | 1998 | 9836052 | |
| in vitro inhibitory effects of dna topoisomerase ii by fernane-type triterpenoids isolated from a euphorbia genus. | several kinds of naturally occurring fernane-type triterpenoids isolated from a euphorbia genus were tested on the inhibitory effects of dna topoisomerases i (topo i) and ii (topo ii) activities. a-ring cleaved 3,4-seco-8 beta h-ferna-4(23),9(11)-dien-3-oic acid and its 3-hydroxyl derivative were found to be selective inhibitors of topo ii activity without the stabilization of a dna/topo ii cleavable complex. | 1998 | 9873631 |
| the molluscicidal activity of crown of christ (euphorbia splendens var. hislopii) latex on snails acting as intermediate hosts of schistosoma mansoni and schistosoma haematobium. | the present study describes the action of the latex of euphorbia splendens var. hislopii (e. milli) on species of the genus bulinus and on biomphalaria pfeifferi, intermediate hosts of schistosomiasis in africa, and the brazilian snails b. glabrata, b. tenagophila, and b. straminea, intermediate hosts of schistosomiasis in brazil. the impact of the latex on the egg masses and embryos of b. glabrata was also evaluated. using the standardized methodology of the world health organization for testin ... | 1998 | 9452283 |
| contact dermatitis due to euphorbia pulcherrima willd, simulating a phototoxic reaction. | 1998 | 9506231 | |
| diterpene polyesters from euphorbia seguieriana | an me2co extract of euphorbia seguieriana (euphorbiaceae) afforded seven new diterpene polyesters (1-7). five of them (1-5), having a new parent alcohol that was named 17-hydroxymyrsinol, were structurally related to myrsinol. the other two compounds (6, 7) were new derivatives of the known parent alcohols cyclomyrsinol and lathyrane. the structure elucidations of the new compounds by highfield spectroscopic methods, including 1d and 2d nmr techniques, are described. | 1998 | 9784151 |
| inhibitors of plant copper amine oxidases. | in this review, inhibitors of plant copper amine oxidases from lens esculenta seedlings, pisum sativum seedlings, and euphorbia characias latex are described. reversible competitive inhibitors and non-competitive inhibitors, irreversible active-site directed inhibitors and mechanism-based inactivators are reviewed in regard to their mechanisms of action. | 1998 | 9793836 |
| immediate skin and mucosal symptoms from pot plants and vegetables in gardeners and greenhouse workers. | short-lived occupational skin symptoms of irritant or urticarial nature were commonly reported among 253 attendants in a clinical study on occupational dermatitis in danish gardeners and greenhouse workers. aimed prick or scratch-patch testing for immediate skin and mucosal symptoms was performed in 105 persons with plants as is. 35 persons (33%) had at least 1 positive reaction and a family history of, or personal, atopy was significantly more prevalent among these compared to attendants with n ... | 1998 | 9817221 |
| intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord diseases. | resiniferatoxin (rtx), a substance isolated from some species of euphorbia, a cactus-like plant, shows pharmacological effects similar to those of capsaicin. we have studied the possibility of treating detrusor hyperreflexia refractory to intravesical capsaicin in patients with chronic spinal cord injuries, thereby providing insight into the mechanism of action of rtx on sensory neurons and its possible future pharmacological and clinical use. | 1998 | 9825395 |
| comparative analysis of the vascular actions of diterpenes isolated from euphorbia canariensis. | we have analysed the effects of 2,3-diepiingol 7,12-diacetate-8-isobutyrate (compound 1), ingenol-3-angelate-17-benzoate (compound 2), ingenol-3-angelate-17-benzoate-20-acetate (compound 3) and 3,5,7,8,9,15-hexahydroxyjatropha-6(17),11-dien-14-one-5,8-bi s(2-methylbutyrate)-7-(2-methylpropionate) (compound 4), four diterpenes isolated from e. canariensis, on the isometric tension developed by isolated rabbit basilar and carotid arteries. concentration-response curves to these compounds were obta ... | 1998 | 9580339 |
| screening of australian medicinal plants for antiviral activity. | extracts of 40 different plant species used in the traditional medicine of the australian aboriginal people have been investigated for antiviral activity. the extracts have been tested for activity against one dna virus, human cytomegalovirus (hcmv) and two rna viruses, ross river virus (rrv) and poliovirus type 1, at non-cytotoxic concentrations. the most active extracts were the aerial parts of pterocaulon sphacelatum (asteraceae) and roots of dianella longifolia var. grandis (liliaceae), whic ... | 1998 | 9582007 |
| dietary cancer risk conditional cancerogens in produce of livestock fed on species of spurge (euphorbiaceae). i. skin irritant and tumor-promoting ingenane-type diterpene esters in e. peplus, one of several herbaceous euphorbia species contaminating fodder of livestock. | the hypothesis was proposed that there is a risk of dietary cancer from conditional cancerogens in produce of livestock polluted with irritants of the diterpene ester type, picked up by feeding on species of euphorbiaceae (spurge). to challenge this, several herbaceous plants of the genus euphorbia, widespread as weeds and contaminants of livestock fodder, were identified botanically and extracts of their aerial parts were tested for irritancy on the mouse ear. as compared to a standard probe of ... | 1998 | 9619738 |
| dietary cancer risk from conditional cancerogens in produce of livestock fed on species of spurge (euphorbiaceae). ii. pathophysiological investigations in lactating goats fed on the skin irritant herb euphorbia peplus and in their milk-raised kids. | lactating goats were fed on aerial parts of the herb euphorbia peplus l. admixed with their usual green fodder. during the experimental feeding period they showed symptoms of general poisoning. in necropsy the main toxic effects were seen in the heart, lung and liver. histopathological examinations revealed that the primary toxic effects originated from degenerative changes in parenchymal and endothelial cells. adverse symptoms in the liver and kidney were also reflected in an alteration of the ... | 1998 | 9619744 |
| macrocyclic diterpenoids from euphorbia semiperfoliata. | in addition to known compounds, the aerial parts of e. semiperfoliata afforded an abietanolide (3), 13 jatrophane polyesters (4-9, 12, 14-19), two 4-deoxyphorbol diesters (23, 24), and a pair of epimeric diterpenes (21, 22) with a novel carbon skeleton, which was named euphoperfoliane. structures were determined by spectroscopic analysis, and the main conformational features of jatropha-6(17),11-dienes are discussed in detail. the obtained isolation yield of several jatrophanes was unprecedented ... | 1998 | 9644058 |
| study of the anti-hyperglycemic effect of plants used as antidiabetics. | the purpose of this research was to study the anti-hyperglycemic effect of 28 medicinal plants used in the treatment of diabetes mellitus. each plant was processed in the traditional way and intragastrically administered to temporarily hyperglycemic rabbits. the results showed that eight out of the 28 studied plants significantly decrease the hyperglycemic peak and/or the area under the glucose tolerance curve. these plants were: guazuma ulmifolia, tournefortia hirsutissima, lepechinia caulescen ... | 1998 | 9683340 |
| dietary cancer risk from conditional cancerogens in produce of livestock fed on species of spurge (euphorbiaceae). iii. milk of lactating goats fed on the skin irritant herb euphorbia peplus is polluted by tumor promoters of the ingenane diterpene ester type. | special procedures were developed to investigate poisonous milk of lactating goats fed experimentally on aerial parts of the herb euphorbia peplus l. in extracts of the milk, weakly irritant in the mouse-ear assay, three diterpene ester toxins were detected by techniques of high-performance liquid chromatography. they are of the ingenane structural type: euphorbia factor pel (ingenol 20-acetate 3-angelate), euphorbia factor pe2 (20-deoxyingenol 3-angelate) and euphorbia factor pe4 (20-deoxyingen ... | 1998 | 9692836 |
| characterization of euphorbia characias latex amine oxidase. | a copper-containing amine oxidase from the latex of euphorbia characias was purified to homogeneity and the copper-free enzyme obtained by a ligand-exchange procedure. the interactions of highly purified apo- and holoenzyme with several substrates, carbonyl reagents, and copper ligands were investigated by optical spectroscopy under both aerobic and anaerobic conditions. the extinction coefficients at 278 and 490 nm were determined as 3.78 x 10(5) m-1 cm-1 and 6000 m-1 cm-1, respectively. active ... | 1998 | 9701592 |
| [macrocyclic diterpene polyesters of the jatrophane type from euphorbia esula]. | three new jatrophane diterpenes, esulatin a, b and c (1-3) were isolated and characterized from the whole, undried plant of euphorbia esula. by means of spectral analysis, the structures were established as penta- and heptaesters of hitherto unknown, polyfunctional diterpene parent alcohols. esulatin a (1) and c (3) are the diterpenoids with the highest degree of esterification identified to date from the family euphorbiaceae. | 1998 | 9703704 |
| cloning and characterization of cold-regulated glycine-rich rna-binding protein genes from leafy spurge (euphorbia esula l.) and comparison to heterologous genomic clones. | leafy spurge (euphorbia esula) is a perennial weed which is capable of acclimating to sub-freezing temperatures. we have used the differential display technique to identify and clone a cdna for a cold-regulated gene (cor20) which hybridizes to mrnas that accumulate specifically during the cold acclamation process. the cor20 cdna was used to isolate two different genomic clones. both clones were similar but not identical to each other and the cdna. sequence analysis of the genomic clones indicate ... | 1998 | 9747799 |
| saprophytic and cycloheximide resistant fungi isolated from golden hamster. | healthy hair samples from golden hamsters were examined for the presence of dermatophytes and non-dermatophytes using baiting technique and direct inoculation. thirty-four species and 2 varieties attributed to 17 genera were recovered. paecilomyces variotii (isolated from 84.4% of the examined hair) and aspergillus niger (81.3%) were the more frequent isolates on sabouraud's dextrose agar (sda) without cycloheximide. our results have clearly demonstrated that the hair of hamster was free from tr ... | 1998 | 9768288 |
| distribution and diversity of geminiviruses in trinidad and tobago. | abstract seven crop and eight weed species from 12 agricultural locations in trinidad and tobago were assayed for the presence of whitefly-transmitted geminiviruses (wtgs) by using dot blot hybridization and polymerase chain reaction (pcr) amplification of the n-terminal coat protein sequence with degenerate primers. the amplified fragments were cloned and analyzed by restriction enzyme digestion to determine fragment length polymorphism among the cloned fragments. representative clones were the ... | 1998 | 18944827 |
| conidial germination, infection structure formation, and early colony development of powdery mildew on poinsettia. | abstract powdery mildew disease on poinsettias (euphorbia pulcherrima) growing in commercial greenhouses was first observed in the united states in 1990 and has become an economically significant problem for poinsettia growers in the midwest and northern united states since 1992. the temporal development of infection structures produced by conidial germ tubes of the pathogen (oidium sp.) and the effect of high temperature on their development were investigated using poinsettia leaf disks placed ... | 1998 | 18944978 |
| phytoplasma induced free-branching in commercial poinsettia cultivars. | free-branching poinsettia cultivars that produce numerous axillary shoots are essential for propagating desirable multi-flowered poinsettias (euphorbia pulcherrima wild. klotz). for more than a decade, a biological agent has been suspected to cause free-branching in poinsettias. attempts to identify the branching agent have failed. isolation of the pathogen was accomplished using a living host and it was concluded that an unculturable phytoplasma is the cause of free-branching in poinsettias. th ... | 1997 | 9035146 |
| euphorbium: modern research on its active principle, resiniferatoxin, revives an ancient medicine. | resiniferatoxin, an ultrapotent capsaicin analog present in the latex of euphorbia resinifera, interacts at a specific membrane recognition site (referred to as the vanilloid receptor), expressed by primary sensory neurons mediating pain perception as well as neurogenic inflammation. desensitization to resiniferatoxin is a promising approach to mitigate neuropathic pain and other pathological conditions in which sensory neuropeptides released from capsaicin-sensitive neurons play a crucial role. ... | 1997 | 9064473 |
| purification and characterisation of a novel iso-propanol dehydrogenase from phytomonas sp. | an alcohol dehydrogenase with two identical subunits and a subunit molecular mass of 40,000 was purified from phytomonas sp. isolated from the lactiferous tubes of euphorbia characias. digitonin titration and subcellular fractionation suggest that the enzyme is present in the mitochondrion. it utilises as substrates, primary and secondary alcohols, is specific for nad+ as coenzyme and is inhibited by hgcl(2). the ph optimum for the oxidation of ethanol is 9.5, and for the reverse reaction 8.5. t ... | 1997 | 9106194 |
| analysis of rabbit vascular responses to dbi, an ingol derivative isolated from euphorbia canariensis. | we have analysed the effects of 7,12-o-diacetyl-8-o-benzoil-2,3-diepiingol (dbi), an ingol derivative isolated from e. canariensis, on isometric tension developed by isolated rabbit basilar and carotid arteries. concentration-response curves to dbi (10(-8) - 3 x 10(-5) m) were obtained cumulatively in both arteries at resting tension and active tone (kci, 50 mm). at resting tension, dbi induced a concentration-dependent contraction, which was not inhibited in ca(2+)-free medium. h7 (1-(5-isoquin ... | 1997 | 9178197 |
| plant exposures ... a national profile of the most common plant genera. | plant exposures are the 4th most common cause of poisoning and 85% of those exposures involve the pediatric population. the large number of plant-related exposures and the lack of knowledge about plant toxicity has led to plant paranoia and considerable educational efforts to reduce the number of exposures. these efforts are often dictated by misconceptions and folklore. american association of poison control centers (aapcc) data on all plant exposures for the years 1985-1994 were electronically ... | 1997 | 9251180 |
| euphorbia sap keratouveitis. | 1997 | 9274425 | |
| characterisation of the two malate dehydrogenases from phytomonas sp. purification of the glycosomal isoenzyme. | two nad(h)-dependent malate dehydrogenase (mdh) isoenzymes were detected in phytomonas isolated from the lactiferous tubes of euphorbia characias. the total specific activity in crude extracts using oxaloacetate as substrate was 3.3 u mg-1 of protein. the two isoenzymes had isoelectric points of 6.0 and 7.2, respectively. the acidic isoform represented 80% of the total activity in the cell and was present in the glycosome. it was purified to homogeneity by a method involving hydrophobic interact ... | 1997 | 9297700 |
| urodynamic effects of intravesical resiniferatoxin in humans: preliminary results in stable and unstable detrusor. | resiniferatoxin, a substance isolated from some species of euphorbia, a cactus-like plant, presents pharmacological effects similar to those of capsaicin. we studied the urodynamic effects of intravesical resiniferatoxin* in normal subjects and patients with unstable detrusor contraction to provide insight into the action mechanism of the molecule on sensory neurons and possible future pharmacological and clinical use. | 1997 | 9366319 |
| microbiological screening of indian medicinal plants with special reference to enteropathogens. | the world health organisation (who) has recommended that all member states actively promote native medicines in their country. ten indian medicinal plants were screened for antibacterial activity specific to enteropathogens. diffusion and dilution methods were used to measure the antibacterial activity. allium sativum, camellia sinensis, and chamaesyce hirta showed higher activity when compared to the rest. they had a minimum bactericidal concentration (mbc) of < 100 micrograms/ml and gave inhib ... | 1997 | 9395690 |
| [application of phytotherapy in odontology: the case of euphorbia balsamifera. endodontic clinical trial]. | phytotherapy is a medicinal and ancestral practice in africa. it deals with all the fields of human pathology. we wanted to ascertain the efficacy of some plants used in odontology as euphorbia balsamifera traditionally used as antalgic treatment of acute dental pulpitis. the latex of the plant was caught and treated as to get enough stable paste. we used that paste in the same conditions we use arsenical nerve caustics, a pulpal devitalizer widely used in dental offices. the study carried out o ... | 1997 | 9827145 |
| study of the embryofeto-toxicity of crown-of-thorns (euphorbia milii) latex, a natural molluscicide. | the crude latex of crown-of-thorns (euphorbia milii var. hislopii) is a potent plant molluscicide and a promising alternative to the synthetic molluscicides used in schistosomiasis control. the present study was undertaken to investigate the embryofeto-toxic potential of e. milii latex. the study is part of a comprehensive safety evaluation of this plant molluscicide. lyophilized latex (0, 125, 250 and 500 mg/kg body weight) in corn oil was given by gavage to wistar rats (n = 100) from days 6 to ... | 1997 | 9532242 |
| photodegradation of the molluscicidal latex of "crown-of-thorns" (euphorbia milii var hislopii). | 1997 | 9566235 | |
| evaluation of the molluscicidal properties of euphorbia splendens var. hislopii (n.e.b.) latex: experimental test in an endemic area in the state of minas gerais, brazil. | following the positive results obtained regarding the molluscicidal properties of the latex of euphorbia splendens that were corroborated in laboratory and field tests under restricted conditions, a field study was conducted in experimental streams located in an endemic area. after recording the average annual fluctuations of vectors in three streams, a solution of e. splendens latex at 12 ppm was applied in stream a, a solution of niclosamide at 3 ppm that was applied in stream b and a third st ... | 1997 | 9566245 |
| [isolation and identification of terpenoides and anthraquinones from euphorbia fischeriana]. | in this paper, two terpenoides and one anthraquinone are isolated from the roots of euphorbia fischeriana. their structures are indentified by combination of physical constants and spectrum analysis as boehmerone (i), ent-16a, 17-dihydroxy-atisan-3-one (ii) and physcion (iii). they are found in the plant for the first time. | 1997 | 12572432 |
| terracinolides a and b, two bishomoditerpene lactones with a novel carbon framework from euphorbia terracina. | a methanolic extract of euphorbia terracina l. has been shown to contain two peracylated polyhydroxy terpenoid lactones with a novel c(22) carbon framework. these metabolites, which have been named terracinolides a (1) and b (2), are based on the same parent compound, but differ in the nature of one of the acyl residues. this novel skeletal system is formally derived from the jatrophane framework by addition of a two-carbon fragment on c-17 (jatrophane numbering). | 1996 | 11667040 |
| analyzing the light energy distribution in the photosynthetic apparatus of c4 plants using highly purified mesophyll and bundle-sheath thylakoids. | the chlorophyll fluorescence characteristics of mesophyll and bundle-sheath thylakoids from plant species with the c4 dicarboxylic acid pathway of photosynthesis were investigated using flow cytometry. ten species with the nadp-malic enzyme (nadp-me) biochemical type of c4 photosynthesis were tested: digitaria sanguinalis (l.) scop., euphorbia maculata l., portulaca grandiflora hooker, saccharum officinarum l., setaria viridis (l.) beauv., zea mays l., and four species of the genus flaveria. thi ... | 1996 | 12226432 |
| ingenane diterpenes from euphorbia petiolata. | from the whole plants of euphorbia petiolata, four new ingenane-type diterpenoids, 3,20-o-diacetylingenol 5-o-(2' e,4' z)-tetradecadienoate (1), 5,20-o-diacetylingenol 3- o-(2' e,4' z)-tetradecadienoate (2), ingenol 3-o-(2' e,4' z)-tetradecadienoate (3), and 5,20-o-isopropylidenylingenol 3-o-(2' e,4' z)-tetradecadienoate (4) were isolated. their structures were elucidated by spectroscopic methods and chemical transformations. | 1996 | 17252444 |
| a new flavonoid from euphorbia ebracteolata. | 1996 | 17252476 | |
| cytotoxic triterpenoids from the leaves of euphorbia pulcherrima. | two cytotoxic triterpenes have been isolated from euphorbia pulcherrima. their structures and stereochemistry have been established from nmr, ir, and ei-mass spectroscopy. the compounds were identified as 9,19-cycloart-23-ene-3 beta,25-diol and, 9,19-cycloart-25-ene-3 beta,24-diol. cytotoxicity evaluation was performed using ehrlich ascites tumor cells. while cycloartenol induced no cytotoxic activity against ehrlich ascites tumor cells, both isolated triterpenes exhibited cell inactivating effe ... | 1996 | 8792663 |
| plant exposures: a state profile of the most common species. | plant exposures are the fourth most common cause of poisoning and 86% of those exposures involve the pediatric population. the large number of plant-related exposures and the lack of knowledge about plant toxicity has led to plant paranoia and considerable educational efforts to reduce the number of exposures. these efforts are often dictated by misconceptions and folklore. aapcc tess data on all plant exposures for the years 1985-1994 were electronically analyzed by plant species and state to e ... | 1996 | 8829350 |
| tumor promoter-like activity of the molluscicidal latex of 'crown-of-thorns' (euphorbia milii var. hislopii) in the v79 metabolic cooperation assay. | the latex of 'crown-of-thorns' (euphorbia milii var. hislopii, syn. e. splendens) has been shown to be a potent plant molluscicide that could be used against the snails which are intermediate hosts of schistosoma trematodes. however, a comprehensive toxicological evaluation of the latex is necessary before its large-scale use in schistosomiasis control becomes possible. in fact, one cause for concern is the presence of tumor-promoting phorbol esters in several plants of the euphorbiaceae family. ... | 1996 | 9196556 |
| [studies on chemical constituents of roots of euphorbia pekinensis]. | nine compounds were isolated from the roots of euphorbia pekinensis rupr., a traditional chinese medicine. by combination of chemical methods and spectral analyses, the structures of the compounds were identified as lanosterol (i), octadecanyl-3-methoxy-4-hydroxybenzeneacrylate (ii), beta-sitosterol (iii), 7-hydroxycoumarin (iv), 2, 2'-dimethoxy-3, 3'-dihydroxy-5, 5'-oxygen-6, 6'-biphenylformic anhydride (v), d-pinoresinol (vi), quercetin (vii), 3, 4-dimethoxybenzoic acid (viii) and 3, 4-dihydro ... | 1996 | 9772694 |
| selectively cytotoxic diterpenes from euphorbia poisonii. | bioactivity-guided fractionation of the latex of euphorbia poisonii pax. (euphorbiaceae) led to the isolation and characterization of a new tigliane diterpene, 12-deoxyphorbol 13-(9,10-methylene)undecanoate (3), together with five known diterpenes (1,2,4-6). when evaluated for cytotoxicity in a panel of six human solid tumor cell lines, the diterpene esters, 1-3, 5, and 6, were selectively cytotoxic for the human kidney carcinoma (a-498) cell line with potencies for 2 and 3 exceeding that of adr ... | 1996 | 8632402 |
| evaluation of the mutagenicity of the molluscicidal latex of christ's crown (euphorbia milii var. hislopii) in mammalian cells in vitro and in vivo. | the latex of christ's crown (euphorbia milii var. hislopii, syn. e. splendens var. hislopii) is a highly active plant molluscicide and could be used for snail control to reduce the prevalence of schistosomiasis in endemic areas. in the course of its toxicological evaluation, the mutagenicity of the latex of euphorbia milii was tested in mammalian cells in vitro and in vivo. latex was investigated for its capability of inducing gene mutations and chromosome aberrations in v79 cells in the absence ... | 1996 | 8637506 |
| aleppicatines a and b from euphorbia aleppica. | two new pentacyclic diterpene polyesters, aleppicatine a and b, have been isolated from the acetone extract of the whole plant of euphorbia aleppica, in addition to five known cycloartane-type triterpenes (24-methylenecycloartanol, cyclolaudenol cycloart-25-en-3 beta-ol-24-one, cycloart-22-en-3 beta,25-diol and cycloart-25-en-3 beta,24-diol), scopoletin, kaempferol and 4-hydroxybenzoic acid and its methyl ether. the structures of the new compounds and their hydrolysis products have been extensiv ... | 1996 | 8688177 |
| an investigation of some turkish herbal medicines in salmonella typhimurium and in the comet assay in human lymphocytes. | medicinal plants play a major role in the life of turkish people and of late medicinal plant usage has increased in many countries. green plants in general contain mutagenic and carcinogenic substances, but there is little information about the biological activities of herbal medicine. in the present study, therefore, various turkish medicinal herbs were investigated for their genotoxic potential in the salmonella typhimurium microsomal activation assay and the alkaline single cell gel electroph ... | 1996 | 8875742 |
| poinsettia exposures have good outcomes...just as we thought. | the poinsettia (euphorbia pulcherrima) is a much-maligned plant which is thought by the public and some health professionals to be extremely toxic. despite pronouncements by public health officials to the contrary, the poinsettia continues to be recognized as a poisonous plant. to determine if there was any validity to the toxicity claims, 849,575 plant exposures reported to the american association of poison control centers were electronically analyzed. poinsettia exposures accounted for 22,793 ... | 1996 | 8906768 |
| an m(r) 145,000 low-density lipoprotein (ldl)-binding protein is conserved throughout the kinetoplastida order. | in view of the importance of the low-density lipoprotein (ldl)-receptor in trypanosoma brucei, we have examined whether other bloodstream trypanosomes of medical and veterinary importance (t.b. rhodesiense, t. equiperdum, t. vivax, t. congolense), but also related parasites developing in mammalian (leishmania donovani) and non-mammalian hosts (crithidia luciliae and phytomonas sp. isolated from euphorbia), would possess an ldl-receptor of their own. (1) all these parasites specifically accumulat ... | 1996 | 8919994 |
| new 19-acetoxyingol diterpenes from the latex of euphorbia poisonii (euphorbiaceae). | the poisonous latex of euphorbia poisonii gave bioactive 3,12-diacetyl-8-nicotinyl-7-phenylacetyl 19-acetoxyingol (1) together with its less active congeners, 3,12-diacetyl-7-phenylacetyl 19-acetoxyingol (2) and 3-acetyl-7-phenylacetyl 19-acetoxyingol (3). the chemical structures of 1-3 were determined by spectroscopic methods including hrms, dept, hetcor, cosy, noesy, hmqc and hmbc. the absolute configurations of the hydroxylated carbons in 2 and 3 were provisionally suggested by the mosher est ... | 1996 | 8931937 |
| euphorbia sap keratopathy: four cases and a possible pathogenic mechanism. | to report four cases of euphorbia sap causing anterior segment toxicity. | 1996 | 8942380 |
| constituents from the stem wood of euphorbia quinquecostata with phorbol dibutyrate receptor-binding inhibitory activity. | bioassay-guided fractionation of an etoac extract of the stem wood of euphorbia quinquecostata using a phorbol dibutyrate receptor-binding assay system as a monitor yielded four inhibitory isolates (1-4), inclusive of one new compound, 17-hydroxyingenol 20-hexadecanoate (1), and three previously known compounds, ingenol 20-hexadecanoate (2), ent-16 alpha,17-dihydroxyatisan-3-one (3), and ent-3 beta,16 alpha,17-trihydroxyatisane (4). also isolated from this extract were 10 constituents inactive i ... | 1996 | 8946746 |