Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| lipases production by bacillus circulans under mesophilic and osmophilic conditions. factors affecting lipases production. | a facultative osmophilic bacterium able to produce lipases (isolated from bee honey) was identified as bacillus circulans. factors affecting lipases production by such isolate were studied. dox's liquid medium supplied with 2 and/or 30% sucrose was used as a basal medium, under static culture condition, for such a purpose. results have showed that the optimal sucrose concentration at which the isolate produced its maximal yield of lipases was 30% after an incubation period of 24 hours at 40 degr ... | 1983 | 6681018 |
| bu-2470, a new peptide antibiotic complex. i. production, isolation and properties of bu-2470 a, b1 and b2. | a strain of bacillus circulans produced a complex of basic peptide antibiotics designated bu-2470, which was found to contain four active components, a, b1, b2a and b2b. bu-2470 a specifically inhibited various pseudomonas species including p. aeruginosa, p. maltophilia and p. putida, but otherwise its antibacterial spectrum was limited to certain gram-negative organisms. bu-2470 b1 and b2 (b2a + b2b) showed broad antibiotic activity against gram-positive and gram-negative bacteria including pse ... | 1983 | 6874583 |
| aerobic mesophilic and psychrotrophic sporeforming bacteria in buffalo milk. | seasonal variation of the population of aerobic sporeformers in raw milk was higher in summer than in other seasons. least variation was in fall, but variation in winter and spring was similar. aerobic mesophilic sporeformers in raw milk consisted mainly of bacillus subtilis (42.5%) and bacillus megaterium (34.8%), followed by bacillus circulans (4.9%), bacillus cereus (4.6%), bacillus pumilus (2.9%), bacillus polymyxa (2.8%), bacillus licheniformis (1.9%), bacillus badius (1.5%), bacillus brevi ... | 1983 | 6886164 |
| the sequence of an antibiotic resistance gene from an antibiotic-producing bacterium. homologies with transposon genes. | the aph gene of a butirosin-producing bacillus circulans has been cloned and sequenced; a comparison of the translated protein sequence with those from tn5 and tn903 indicates that they may have a common origin. | 1983 | 6193008 |
| bu-2743e, a leucine aminopeptidase inhibitor, produced by bacillus circulans. | 1983 | 6643284 | |
| [taxonomy of bacillus circulans]. | four strains of bacillus circulans sensu stricto (atcc 4513 (type strain), 4515, 4516, and 4530) were subjected to 236 morphological, biochemical and physiological tests, including 162 carbon source utilization tests. b. circulans s. s. is a species of facultative anaerobes able to ferment carbohydrates. many carbohydrates and a few aliphatic acids were used as sole carbon and energy sources, but amino acids were not. the guanine-plus-cytosine content of dna (four strains studied) was 37.2 +/- 0 ... | 1983 | 6651128 |
| effects of nitric oxide and nitrogen dioxide on bacterial growth. | the effects of low concentrations of nitric oxide (no) and nitrogen dioxide (no2) on actively dividing cultures of staphylococcus aureus, micrococcus luteus, micrococcus roseus, serratia marcescens, bacillus subtilis, bacillus circulans, bacillus megaterium, and bacillus cereus were studied. fresh cultures of each organism were incubated for 24 h at 25 degrees c on both nutrient agar and mineral salts glucose agar plates under atmospheres containing various low concentrations of no in air (0 to ... | 1983 | 6351744 |
| a plasmid which does not encode the aminoglycoside phosphotransferase in the butirosin-producing strain of bacillus circulans. | bacillus circulans nrrl b-3312 produces the aminoglycoside antibiotic butirosin and encodes an aminoglycoside 3'-phosphotransferase. we detected a 48 kilobase plasmid, pip850, in this strain; this was analyzed by agarose gel electrophoresis following digestion with ecori restriction endonuclease and by nucleic acid hybridization. the results obtained indicate that plasmid pip850 does not carry the structural gene for the aminoglycoside modifying enzyme. | 1982 | 6179916 |
| biosynthetic pathway of 2-deoxystreptamine. | four 2-deoxystreptamine (dos) related compounds including s-11-p, isolated as an intermediate of dos biosynthesis, were supplemented to the culture of a dos- mutant of bacillus circulans. among the tested aminocyclitol compounds, s-11-p alone was converted to dos. addition of other aminocyclitols neither produced antibiotic nor inhibited the incorporation of s-11-p and dos into butirosins. by these facts, s-11-p was confirmed clearly to be an intermediate of dos biosynthesis. | 1981 | 7251504 |
| isolation of an intermediate of 2-deoxystreptamine biosynthesis from a mutant of bacillus circulans. | eight 2-deoxystreptamine-negative (dos-) mutants were isolated from various strains of bacillus circulans, normally producing butirosin, xylostasin and ribostamycin. these mutants were classified into two groups (converter and secretor) by the simple method of cosynthesis using agar plate culture. one of the cosynthetic pairs, strain s-11, an intermediate of dos biosynthesis, s-11-p, was isolated. this compound was converted to butirosin (btn) effectively by strain 236. the structure of s-11-p w ... | 1980 | 7429985 |
| structure elucidation of an intermediate of 2-deoxystreptamine biosynthesis. | the structure of a 2-deoxystreptamine (dos) precursor named s-11-p, which was isolated by using a dos negative mutant derived from a xylostasin-producing strain of bacillus circulans b15m, has been elucidated as (1 l)-1,3,5/2,4,-5-aminocyclohexanetetrol by comparison with an authentic specimen, which was synthesized from kanamycin a. | 1980 | 7429986 |
| production of a new aminoglycoside antibiotic by a mutant of bacillus circulans. | a new aminoglycoside antibiotic, s-11-a, was isolated from the fermentation broth of the 2-deoxystreptamine negative (dos-) mutant of bacillus circulans s-11. the structure of s-11-a was elucidated as 1-deamino-1-hydroxyxylostasin, which contains an intermediate of dos biosynthesis (s-11-p) and has resistance to some aminoglycoside-inactivating enzymes. this is the first finding of antibiotic production by a dos- mutant without any supplementation of dos or a dos analog, and could be described a ... | 1980 | 7429987 |
| the structure of permetin a, a new polypeptin type antibiotic produced by bacillus circulans. | the structure of permetin a(i), an antibiotic substance produced by bacillus circulans aj 3902, has been elucidated as a cyclic acyl peptide by means of the mass and nuclear magnetic resonance spectroscopic techniques. (formula: see text.) the structure was found to be the same as polypeptin a(ii) except that l-thr in ii is replaced by l-ser in i. details of the structural determination are given for the permetin a itself as well as for the hydrolyzed permetin a. (formula: see text.) | 1979 | 438100 |
| isolation of a new peptide antibiotic, permetin a, from bacillus circulans. | permetin a was purified from the culture filtrate of bacillus circulans aj 3902 by extraction with n-butanol, precipitation with sodium helianthate, cm-cellulose column chromatography and sephadex lh-20 column chromatography. the compound was found to be a new peptide antibiotic containing 2,4-diaminobutyric acid (dab), leucine, isoleucine, phenylalanine, valine, serine (in a molar ratio of 3:2:1:1:1:1) and a fatty acid. this antibiotic showed activity in vitro against gram-negative, gram-positi ... | 1979 | 438099 |
| susceptibility to butirosin and neomycin b in bacillus circulans, the butirosin-producing organism. | butirosin, an aminoglycoside antibiotic, is produced by bacillus circulans b-3312. experiments using recombined ribosomal and supernatant fractions from this strain and from b. megaterium km have shown that the ribosome of both are sensitive to butirosin. the aminoglycoside 3'-phosphotransferase present in b. circulans modifies butirosin and neomycin in vitro but confers resistance only to the former in vivo. the phosphotransferase does not modifya detectable amount of extracellular butirosin wh ... | 1979 | 93616 |
| ribostamycin production by a mutant of butirosin producing bacteria. | by the use of our improved colony selection technique, xylostasin and ribostamycin producing mutants were isolated from nitrosoguanidine treated bacillus circulans b15m, a producer of butirosins a and b. among these structurally related aminoglycosides, ribostamycin is the well-known product of a steptomyces and has not been isolated as a bacterial metabolite. a selected mutant of strain 306, which produces xylostasin and ribostamycin, was futher mutagenized in expectation of getting an improved ... | 1978 | 81827 |
| mutational biosynthesis of butirosin analogs. iii. 6'-n-methylbutirosins and 3', 4'-dideoxy-6'-c-methylbutirosins, new semisynthetic aminoglycosides. | two pairs of butirosin analogs were isolated from the fermentation broths obtained by cultivating a neamine-negative mutant of the butirosin-producing organism bacillus circulans in the medium supplemented with 6'-n-methylneamine and gentamine c2, respectively. these amtibiotics were characterized as 6'-n-mentylbutirosins a and b (nmb-a & nmb-b), and 3', 4'-dideoxy-6'-c-methylbutirosins a and b (dcb-a & dcb-b), respectively, by chemical and spectroscopic studies. nmb-a and nmb-b exhibited broad- ... | 1978 | 81824 |
| mutational biosynthesis of butirosin analogs. ii. 3', 4'-dideoxy-6'-n-methylbutirosins, new semisynthetic aminoglycosides. | a pair of new butirosin analogs was isolated from the fermentation broth obtained by cultivating a neamine-negative mutant of the butirosin-producing organism bacillus circulans in the medium supplemented with 6'-n-methylgentamine c1a. these antibiotics were characterized and elucidated as 3', 4'-dideoxy-6'-n-methylbutirosins a and b (dmb-a & dmb-b), by chemical and spectroscopic studies. dmb-a and dmb-b exhibited broad-spectrum antibacterial activities with in vitro potency similar to or slight ... | 1978 | 81823 |
| mutational biosynthesis of butirosin analogs. i. conversion of neamine analogs into butirosin analogs by mutants of bacillus circulans. | by n-methyl-n'-nitro-n-nitrosoguanidine treatment, neamine-negative mutants which required neamine for biosynthesis of butirosins were obtained from a butirosin-producing organism bacillus circulans. these mutants also produced butirosins from paromamine and could be divided into two types i and ii. mutants of type i could not produce butirosins from 2-deoxystreptamine, whereas those of type ii could. two typical mutants mcrl 5003 (type i) and mcrl 5004 (type ii) could produce butirosin analogs, ... | 1978 | 81822 |
| simple method for the isolation of astaxanthin from the basidiomycetous yeast phaffia rhodozyma. | a method is described for the quantitative and, possibly, large-scale extraction of astaxanthin from the yeast phaffia rhodozyma. the method utilizes extracellular enzymes produced by the bacterium bacillus circulans wl-12, which partially digests the yeast cell wall and renders the carotenoid pigments extractable by acetone or ethanol. complete recovery of astaxanthin from heat-killed p. rhodozyma cells was obtained after growing b. circulans wl-12 on these yeast cells for 26 h and then extract ... | 1978 | 28079 |
| aminoglycoside 3'-phosphotransferase in bacillus circulans producing butirosins. | 1977 | 69624 | |
| the enzymic degradation of an alkali-soluble glucan from the cell walls of saccharomyces cerevisiae. | an alkali-soluble glucan from the cell walls of saccharomyces cerevisiae ncyc1109 has been hydrolysed with a purified endo-(1 leads to 3)-beta-d-glucanase and an endo-(1 leads to 6)-beta-d-glucanase from bacillus circulans wl-12. the products of enzyme action include various oligosaccharide and polysaccharide fractions which have been separated by gel filtration and characterized, giving new information on the fine structure of the glucan. the isolated cell walls have also been subjected to enzy ... | 1977 | 323412 |
| cell wall studies of histoplasma capsulatum and blastomyces dermatitidis using autologous and heterologous enzymes. | enzymes capable of hydrolyzing cell walls of blastomyces dermatitidis and chemotypes i and ii of histoplasma capsulatum were prepared in the laboratory or obtained from commercial sources. they included chitinases, beta-1,3-glucanases, beta-1,6-glucanase, and pronase. monosaccharides and disaccharides of glucose released from the cell walls by the enzymes were determined qualitatively by paper and gas-liquid chromatography, and monosaccharides were quantitated by the latter technique as well. an ... | 1977 | 870437 |
| aminoglycoside-modifying enzyme of an antibiotic-producing bacterium acts as a determinant of antibiotic resistance in escherichia coli. | bacillus circulans nrrl b-3312, a nonpathogenic bacterium that produces the aminoglycoside antibiotic butirosin, is known to contain an aminoglycoside phosphotransferase that is similar to the neomycin phosphotransferases of clinically isolated antibiotic-resistant bacteria. purified dnas from b. circulans and the plasmid cole1-apr were digested with ecori endonuclease and the resulting fragments covalently joined with polynucleotide ligase. the recombined dna was used to transform e. coli and a ... | 1977 | 322154 |
| lysis of yeast cell walls. lytic beta-(1 leads to 6)-glucanase from bacillus circulans wl-12. | when grown in a mineral medium with yeast cell walls or yeast glucan as the sole carbon source, bacillus circulans wl-12 produces wall-lytic enzymes in addition to non-lytic beta-(1 leads to 3) and beta-(1 leads to 6)-glucananases. the lytic enzymes were isolated from the culture liquid by adsorption on insoluble yeast glucan in batch operation. after digestion of the glucan, the mixture of enzymes was chromatographed on hydroxylapatite on which the lytic activity could be resolved into one lyti ... | 1976 | 4309 |
| isolation of a new antibiotic 333-25, related to antibiotic em 49. (studies on antibiotics from the genus bacillus. xi). | a new antibiotic, 333-25, active against gram-positive and gram-negative bacteria, was isolated from the culture broth of bacillus circulans 333-25. the antibiotic is a basic acylpeptide containing 2,4-diaminobutyric acid (5), leucine (2), phenylalanine (1) and a fatty acid. it is closely related to antibiotic em 49, but can be differentiated by chromatographic behaviour. | 1976 | 956039 |
| peptidoglutaminase (bacillus circulans). | 1976 | 1012012 | |
| isolation of a new peptide antibiotic complex, b-43 (studies on antibiotics from the genus bacillus. xv). | a new peptide antibiotic complex b-43, active against gram-positive and gram-negative bacteria, was isolated from a strain of bacillus circulans. this antibiotic contains aspartic acid, valine, isoleucine, leucine, phenylalanine and 2,4-diaminobutyric acid. it seems to be related to polypeptin and antibiotic complex 4205, but differs in that it contains aspartic acid residue. | 1976 | 993119 |
| microorganism capable of decomposing n-acetylglucosaminyl ribitol teichoic acid of staphylococcus aureus. | enzyme(s) capable of decomposing n-acetylglucosaminyl ribitol teichoic acid prepared from the cell wall of staphylococcus aureus fda 209 p was obtained from the culture supernatant of a gram-negative, rod-shaped, spore-forming soil bacterium. properties of the bacterium were very similar to those of bacillus circulans. | 1976 | 948143 |
| structure of the peptide antibiotic polypeptin. | polypeptin, a basic peptide antibiotic isolated from bacillus circulans, was separated into two components by countercurrent distribution. the two components, polypeptin a and polypeptin b, had identical amino acid compositions but varied in the structure of the hydroxy acid constituent attached to the alpha-amino group of the peptide chain. polypeptin a contained 3-hydrosy-4-methylhexanoic acid and polypeptin b contained 3-hydrosy-5-methylhexanoic acid. t-he sterochemistry of these hydroxy acid ... | 1976 | 186604 |
| antibiotics derived from a mutant of bacillus circulans. | a mutant of bacillus circulans, which produces butirosins only when 2-deoxystreptamine is added to the fermentation medium, was employed in the biosynthesis of antibiotics containing modified aminocyclitols. the blocked mutant converted 2,5-dideoxystreptamine into 5-deoxybutirosamine. streptamine was incorporated into a complex differing from butirosin by an additional hydroryl at c-2. | 1976 | 60328 |
| lysis of yeast cell walls. lytic beta-(1 leads to 3)-glucanases from bacillus circulans wl-12. | bacillus circulans wl-12 when grown in a mineral medium with yeast cell walls or yeast glucan as the soli carbon source, produced five beta-glucanases. two beta-(1 leads to 3)-glucanases (i and ii), which are lytic to yeast cell walls, were isolated from the culture liquid by batch adsorption on yeast glucan, and separated by chromatography on hydroxylapatite. lytic beta-(1 leads to 3)-glucanase i was further purified by carboxymethylcellulose chromatography. the specific activity of lytic beta- ... | 1976 | 4310 |
| chemical and physical properties of peptidoglutaminase i and ii from bacillus circulans. | some chemical and physical properties of peptidoglutaminase i and ii have been determined. for example, molecular weight, isoelectric point, intrinsic viscosity, partial specific volume, sedimentation and diffusion coefficient were 89 000 and 105 000, ph = 4.1 and 4.0, 0.042 and 0.065 dl/g, 0.733 and 0.728 ml/g, 5.85 and 5.3 s, 5.32 and 4.57-10(-7) cm2-s-1, respectively. their amino acid compositions were also determined. between them, peptidoglutaminanse ii was a glycoprotein containing 2 mol o ... | 1976 | 816382 |
| fine structure and distribution of extracellular polymer surrounding selected aerobic bacteria. | the structure and distribution of extracellular polymer surrounding bacillus circulans, diplococcus (streptococcus) pneumoniae, streptococcus salivarius, staphylococcus aureus, klebsiella pneumoniae, pseudomonas aeruginosa, herella vaginacola (acinetobacter calcoaceticus), and agrobacterium tumefaciens were studied by electron microscopy. a modified ruthenium red staining procedure was used to examine the fine structure of capsule and slime. freeze-etching and critical-point drying were used to ... | 1975 | 46774 |
| lysis of yeast cell walls: glucanases from bacillus circulans wl-12. | endo-beta-(1 --> 3)- and endo-beta-(1 --> 6)-glucanases are produced in high concentration in the culture fluid of bacillus circulans wl-12 when grown in a mineral medium with bakers' yeast cell walls as the sole carbon source. much lower enzyme levels were found when laminarin, pustulan, or mannitol was the substrate. the two enzyme activities were well separated during sephadex g-100 chromatography. the endo-beta-(1 --> 3)-glucanase was further purified by diethylaminoethyl-cellulose and hydro ... | 1974 | 4407251 |
| demonstration of a fibrillar component in the cell wall of the yeast saccharomyces cerevisiae and its chemical nature. | the ultrastructure of isolated cell walls of saccharomyces cerevisiae from the log and stationary phases of growth was studied after treatment with the following enzymes: purified endo-beta-(1 --> 3)-glucanase and endo-beta-(1 --> 6)-glucanase produced by bacillus circulans; purified exo-beta-glucanase and endo-beta-(1 --> 3)-glucanase produced by schizosaccharomyces versatilis; commercial pronase. while exo-beta-glucanase from s. versatilis had no electron microscopically detectable effect on t ... | 1974 | 4135002 |
| butirosin, a new aminoglycosidic antibiotic complex: bacterial origin and some microbiological studies. | butirosin, a new aminoglycosidic antibiotic complex, was produced by submerged fermentation with each of two strains of bacillus circulans. a paper-disc, agar-diffusion assay which employs escherichia coli (p-d 04863) as the test organism has been developed. shaken-flask and stirred-jar fermentations in a medium containing glycerol, soybean meal, meat peptone, ammonium chloride, and calcium carbonate reach titers of 500 to 700 mug of butirosin base per ml. butirosin is active against several gra ... | 1972 | 4207954 |
| [identification of 2 protein components in the flagella of bacillus circulans]. | 1972 | 4649778 | |
| butirosin, a new aminoglycosidic antibiotic complex: isolation and characterization. | butirosin, a new water-soluble aminoglycosidic antibiotic complex, active against gram-positive and gram-negative bacteria, has been isolated from fermentation filtrates of bacillus circulans by ion exchange. the complex has been resolved into isomeric a and b components, c(21)h(41)n(5)o(12), by means of dowex 1 x 1 or dowex 1 x 2 chromatography. properties of the free bases and the n, n', n'', n'''-tetraacetyl derivatives of butirosin a and b are given. | 1972 | 4670491 |
| purification of phosphomannanase and its action on the yeast cell wall. | an improved assay for phosphomannanase (an enzyme required for the preparation of yeast protoplasts) has been developed based on the release of mannan from yeast cell walls. a procedure for the growth of bacillus circulans on a large scale for maximal production of the enzyme is described. the culture medium containing the secreted enzyme was concentrated, and the enzyme was purified by protamine sulfate treatment, ammonium sulfate fractionation, gel filtration on p-100, and isoelectric density ... | 1970 | 4908677 |
| [demonstration of the nuclear structure of bacillus circulans by freeze etching]. | 1970 | 4918987 | |
| enzymatic hydrolysis of yeast cell walls. i. isolation of wall-decomposing organisms and separation and purification of lytic enzymes. | tanaka, hirosato (university of california, davis), and herman j. phaff. enzymatic hydrolysis of yeast cell walls. i. isolation of wall-decomposing organisms and separation and purification of lytic enzymes. j. bacteriol. 89:1570-1580. 1965.-a number of microorganisms, able to decompose and grow on yeast cell walls, were isolated from soil. these isolates demonstrated various types of attack on yeast walls. a bacterium, identified as bacillus circulans, and a species of streptomyces produced cle ... | 1965 | 14291597 |
| purification and properties of beta-1,3-glucanase from the "lytic enzyme" of bacillus circulans. | 1963 | 13961785 | |
| a strain of bacillus circulans capable of growing under highly alkaline conditions. | 1961 | 13693164 | |
| germination under alkaline conditions and transmission of alkali resistance by endospores of certain strains of bacillus cereus and bacillus circulans. | 1961 | 13693165 | |
| effect of lytic enzyme from bacillus circulans and chitinase from streptomyces sp. on aspergillus oryzae. | 1959 | 13622735 | |
| polypeptin, an antibiotic from a member of the bacillus circulans group. ii. purification, crystallization, and properties of polypeptin. | 1950 | 14794681 | |
| circulin an antibiotic from an organism resembling bacillus circulans. | 1949 | 16561679 | |
| on the naming of two antibiotics from members of the bacillus circulans group: circulin and polypeptin. | 1949 | 16561756 | |
| circulin, an antibiotic from an organism resembling bacillus circulans. | 1949 | 18116908 | |
| on the naming of two antibiotics from members of the bacillus circulans group; circulin and polypeptin. | 1949 | 18151943 | |
| circulin, an antibiotic from a member of the bacillus circulans group; bacteriological studies. | 1948 | 18101388 | |
| circulin, an antibiotic from a member of the bacillus circulans group: i. bacteriological studies. | 1948 | 16561627 |