Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [diagnosis and treatment of hepatic hematomas in pre-eclampsia]. | 2013 | 3736165 | |
| the solubility controversy of paired helical filaments: a commentary. | 2013 | 3574590 | |
| effects of different insulin administration modalities on vitamin d metabolism of insulin-dependent diabetic patients. | 2013 | 3551545 | |
| [a longitudinal study of dental caries prevalence of "h" primary school children in choong-chung-book-do]. | 2013 | 3869191 | |
| inspissated bile in a neonate with cystic fibrosis. | 2013 | 3520008 | |
| bacteroides thetaiotaomicron and faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent. | the intestinal mucus layer plays a key role in the maintenance of host-microbiota homeostasis. to document the crosstalk between the host and microbiota, we used gnotobiotic models to study the influence of two major commensal bacteria, bacteroides thetaiotaomicron and faecalibacterium prausnitzii, on this intestinal mucus layer. b. thetaiotaomicron is known to use polysaccharides from mucus, but its effect on goblet cells has not been addressed so far. f. prausnitzii is of particular physiologi ... | 2013 | 23692866 |
| future for probiotic science in functional food and dietary supplement development. | the purpose of this study is to provide an update of probiotic science evolving from classical approaches to the development of next-generation probiotics, parallel to advances in the understanding of the complexity of the gut microbiome and its role in human health. | 2013 | 24071779 |
| faecalibacterium prausnitzii upregulates regulatory t cells and anti-inflammatory cytokines in treating tnbs-induced colitis. | faecalibacterium prausnitzii (f. prausnitzii) is a common anaerobic bacteria colonized in the human gut and inflammatory bowel disease (ibd) patients are usually lack of f. prausnitzii. the aims of this study were to evaluate the anti-inflammatory and immunomodulatory capacity of f. prausnitzii by comparing it with bifidobacterium longum (b. longum) in both cellular and animal experiments. | 2013 | 23643066 |
| decreased abundance of faecalibacterium prausnitzii in the gut microbiota of crohn's disease. | dysbiosis is thought to be relevant to the etiology and pathogenesis of crohn's disease (cd). in this study, we investigated the abundance of faecalibacterium prausnitzii, as well as bilophila wadsworthia, in the gut microbiota of japanese cd patients. | 2013 | 23216550 |
| temporal bacterial community dynamics vary among ulcerative colitis patients after fecal microbiota transplantation. | fecal microbiota transplantation (fmt) from healthy donors, which is an effective alternative for treatment of clostridium difficile-associated disease, is being considered for several disorders such as inflammatory bowel disease, irritable bowel syndrome, and metabolic syndrome. disease remission upon fmt is thought to be facilitated by an efficient colonization of healthy donor microbiota, but knowledge of the composition and temporal stability of patient microbiota after fmt is lacking. | 2013 | 24060759 |
| insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women. | to highlight the contribution of the gut microbiota to the modulation of host metabolism by dietary inulin-type fructans (itf prebiotics) in obese women. | 2013 | 23135760 |
| xylo-oligosaccharides and inulin affect genotoxicity and bacterial populations differently in a human colonic simulator challenged with soy protein. | high dietary intakes of some protein sources, including soy protein, can increase colonic dna damage in animals, whereas some carbohydrates attenuate this. we investigated whether inulin and xylo-oligosaccharides (xos) could be protective against dna strand breaks by adding them to a human colonic simulator consisting of a proximal vessel (pv) (ph 5.5) and a distal vessel (dv) (ph 6.8) inoculated with human faeces and media containing soy protein. genotoxicity of the liquid phase and microbial p ... | 2013 | 24064573 |
| metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters. | roux-en-y gastric bypass (rygb) has become a prominent therapeutic option for long-term treatment of morbid obesity and type 2 diabetes mellitus (t2d). cross talk and pathogenetic consequences of rygb-induced profound effects on metabolism and gut microbiome are poorly understood. the aim of the present study therefore was to characterize intra-individual changes of gut microbial composition before and 3 months after rygb by metagenomic sequencing in morbidly obese patients (body mass index (bmi ... | 2013 | 23032991 |
| arabinogalactan and fructo-oligosaccharides have a different fermentation profile in the simulator of the human intestinal microbial ecosystem (shime ®). | current prebiotics, such as fructo-oligosaccharides (fos), are limited in their persistence in the distal colon and are predominantly fermented in the proximal colon. in order to identify a potential alternative, the differences in the fermentation profile of arabinogalactan (ag) and fos have been assessed in the simulator of the human intestinal microbial ecosystem. the effect of each product on the composition and activity of the microbial community was analysed during a 3-week treatment perio ... | 2013 | 23864575 |
| a gene-targeted approach to investigate the intestinal butyrate-producing bacterial community. | butyrate, which is produced by the human microbiome, is essential for a well-functioning colon. bacteria that produce butyrate are phylogenetically diverse, which hinders their accurate detection based on conventional phylogenetic markers. as a result, reliable information on this important bacterial group is often lacking in microbiome research. | 2013 | 24451334 |
| faecalibacterium prausnitzii supernatant improves intestinal barrier function in mice dss colitis. | objective. the intestinal microbiota plays a substantial role in the pathogenesis of inflammatory bowel disease (ibd). faecalibacterium prausnitzii (fp) is underrepresented in ibd patients and have been suggested to have anti-inflammatory effects in mice. increased intestinal permeability is common in ibd but the relationship between fp and intestinal barrier function has not been investigated. our aim was to study treatment with fp supernatant on intestinal barrier function in a dextran sodium ... | 2013 | 23971882 |
| cystic fibrosis transmembrane conductance regulator (cftr) allelic variants relate to shifts in faecal microbiota of cystic fibrosis patients. | in this study we investigated the effects of the cystic fibrosis transmembrane conductance regulator (cftr) gene variants on the composition of faecal microbiota, in patients affected by cystic fibrosis (cf). cftr mutations (f508del is the most common) lead to a decreased secretion of chloride/water, and to mucus sticky secretions, in pancreas, respiratory and gastrointestinal tracts. intestinal manifestations are underestimated in cf, leading to ileum meconium at birth, or small bowel bacterial ... | 2013 | 23613805 |
| a diet high in resistant starch modulates microbiota composition, scfa concentrations, and gene expression in pig intestine. | resistant starch (rs) is highly fermentable by microbiota in the colon, resulting in the production of scfas. rs is thought to mediate a large proportion of its health benefits, including increased satiety, through the actions of scfas. the aim of this study was to investigate the effects of a diet high in rs on luminal microbiota composition, luminal scfa concentrations, and the expression of host genes involved in scfa uptake, scfa signaling, and satiety regulation in mucosal tissue obtained f ... | 2013 | 23325922 |
| starch structure modulates metabolic activity and gut microbiota profile. | normal maize starch and high amylose maize starch (has) either in native or thermally treated forms were used to investigate the effect of starch structure on the production of metabolites and gut microbiota profile using an anaerobic in vitro system. the changes in starch structure during fermentation were investigated using scanning electron microscopy (sem), high-performance liquid chromatography (hplc) and fourier transform infra-red spectroscopy (ftir). the native normal starch showed a por ... | 2013 | 24113693 |
| faecalibacterium prausnitzii and human intestinal health. | faecalibacterium prausnitzii is the most abundant bacterium in the human intestinal microbiota of healthy adults, representing more than 5% of the total bacterial population. over the past five years, an increasing number of studies have clearly described the importance of this highly metabolically active commensal bacterium as a component of the healthy human microbiota. changes in the abundance of f. prausnitzii have been linked to dysbiosis in several human disorders. administration of f. pra ... | 2013 | 23831042 |
| faecalibacterium prausnitzii and crohn's disease - is there any connection? | the aim of the study was evaluation of the correlation between the level of clinical activity of crohn's disease (cd) and the number of faecalibacterium prausnitzii, total number of bacteria and the concentration of selected short chain fatty acids (scfa) in stool. 34 individuals diagnosed with crohn's disease participated in this study in 2011. the disease activity was determined according to the crohn disease activity index (cdai). the number of faecalibacterium prausnitzii and total number of ... | 2013 | 23829084 |
| intestinal microbiota: a source of novel biomarkers in inflammatory bowel diseases? | the human intestine harbours a complex microbial ecosystem that performs manifold functions important to the nutrition and health of its host. extensive study has revealed that the composition of the intestinal microbiota is altered in individuals with inflammatory bowel disease (ibd). the ibd associated intestinal microbiota generally has reduced species richness and diversity, lower temporal stability, and disruption of the secreted mucus layer structure. multiple studies have identified certa ... | 2013 | 23768552 |
| colonisation by faecalibacterium prausnitzii and maintenance of clinical remission in patients with ulcerative colitis. | although incrimination of the intestinal microbiota in the pathogenesis of ibd is widely accepted, few data are available about the role of specific bacteria. potentially, faecalibacterium prausnitzii, bacteria with anti-inflammatory properties, might be deficient in ulcerative colitis (uc). | 2013 | 23725320 |
| fecal microbial diversity in pre-weaned dairy calves as described by pyrosequencing of metagenomic 16s rdna. associations of faecalibacterium species with health and growth. | in this study, we use barcoded pyrosequencing of the 16s rrna gene to characterize the fecal microbiota of neonatal calves and identify possible relationships of certain microbiota profiles with health and weight gain. fecal samples were obtained weekly from 61 calves from birth until weaning (seventh week of the calves' life). firmicutes was the most prevalent phylum, with a prevalence ranging from 63.84% to 81.90%, followed by bacteroidetes (8.36% to 23.93%), proteobacteria (3.72% to 9.75%), f ... | 2013 | 23646192 |
| the more the merrier: faecalibacterium prausnitzii in crohn's disease. | 2013 | 23614339 | |
| effect of lactobacillus salivarius ls-33 on fecal microbiota in obese adolescents. | this study is a part of the clinical trials with probiotic bacterium lactobacillus salivarius ls-33 conducted in obese adolescents. previously reported clinical studies showed no effect of ls-33 consumption on the metabolic syndrome in the subject group. the aim of the study was to investigate the impact of l. salivarius ls-33 on fecal microbiota in obese adolescents. | 2013 | 23510724 |
| clostridium leptum group bacteria abundance and diversity in the fecal microbiota of patients with inflammatory bowel disease: a case-control study in india. | alterations in the fecal bacterial flora occur in inflammatory bowel disease (ibd). we examined the abundance and diversity of clostridium leptum group, an important group of carbohydrate-fermenting bacteria, in the feces of patients with ibd and compared them with healthy controls. | 2013 | 23351032 |
| in vitro fermentation of commercial α-gluco-oligosaccharide by faecal microbiota from lean and obese human subjects. | the fermentation selectivity of a commercial source of a-gluco-oligosaccharides (bioecolians; solabia) was investigated in vitro. fermentation by faecal bacteria from four lean and four obese healthy adults was determined in anaerobic, ph-controlled faecal batch cultures. inulin was used as a positive prebiotic control. samples were obtained at 0, 10, 24 and 36 h for bacterial enumeration by fluorescent in situ hybridisation and scfa analyses. gas production during fermentation was investigated ... | 2013 | 23116939 |
| resistant starch induces catabolic but suppresses immune and cell division pathways and changes the microbiome in the proximal colon of male pigs. | consumption of resistant starch (rs) has been associated with various intestinal health benefits, but knowledge of its effects on global gene expression in the colon is limited. the main objective of the current study was to identify genes affected by rs in the proximal colon to infer which biologic pathways were modulated. ten 17-wk-old male pigs, fitted with a cannula in the proximal colon for repeated collection of tissue biopsy samples and luminal content, were fed a digestible starch (ds) d ... | 2013 | 24132577 |
| human gut microbiota changes reveal the progression of glucose intolerance. | to explore the relationship of gut microbiota with the development of type 2 diabetes (t2dm), we analyzed 121 subjects who were divided into 3 groups based on their glucose intolerance status: normal glucose tolerance (ngt; n = 44), prediabetes (pre-dm; n = 64), or newly diagnosed t2dm (n = 13). gut microbiota characterizations were determined with 16s rdna-based high-throughput sequencing. t2dm-related dysbiosis was observed, including the separation of microbial communities and a change of alp ... | 2013 | 24013136 |
| commentary: is faecalibacterium prausnitzii a potential treatment for maintaining remission in ulcerative colitis? | 2013 | 23937459 | |
| the type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome 'at-risk' population. | an obese-type human microbiota with an increased firmicutes:bacteroidetes ratio has been described that may link the gut microbiome with obesity and metabolic syndrome (mets) development. dietary fat and carbohydrate are modifiable risk factors that may impact on mets by altering the human microbiome composition. we determined the effect of the amount and type of dietary fat and carbohydrate on faecal bacteria and short chain fatty acid (scfa) concentrations in people 'at risk' of mets. | 2013 | 22410962 |
| the gut anaerobe faecalibacterium prausnitzii uses an extracellular electron shuttle to grow at oxic-anoxic interphases. | faecalibacterium prausnitzii is one of the most abundant bacteria in the human gut ecosystem and it is an important supplier of butyrate to the colonic epithelium. low numbers of faecalibacteria have been associated with inflammatory bowel disease. despite being extremely oxygen sensitive, f. prausnitzii is found adherent to the gut mucosa where oxygen diffuses from epithelial cells. this paradox is now explained on the basis of gas tube experiments, flavin-dependent reduction of 5,5'-dithiobis- ... | 2012 | 22357539 |
| changes of gut bacteria and immune parameters in liver transplant recipients. | liver transplantation is one of the most effective therapeutic options for patients with end-stage liver diseases, and gut microbiota is actively involved in potential infections in pretransplant and posttransplant patients. however, the diversity of gut microbiota and its relationship with the immune parameter of liver transplantation recipients are not well understood. | 2012 | 22251469 |
| microbiota of de-novo pediatric ibd: increased faecalibacterium prausnitzii and reduced bacterial diversity in crohn's but not in ulcerative colitis. | the gastrointestinal microbiota is considered important in inflammatory bowel disease (ibd) pathogenesis. discoveries from established disease cohorts report reduced bacterial diversity, changes in bacterial composition, and a protective role for faecalibacterium prausnitzii in crohn's disease (cd). the majority of studies to date are however potentially confounded by the effect of treatment and a reliance on established rather than de-novo disease. | 2012 | 23044767 |
| inflammatory bowel diseases phenotype, c. difficile and nod2 genotype are associated with shifts in human ileum associated microbial composition. | we tested the hypothesis that crohn's disease (cd)-related genetic polymorphisms involved in host innate immunity are associated with shifts in human ileum-associated microbial composition in a cross-sectional analysis of human ileal samples. sanger sequencing of the bacterial 16s ribosomal rna (rrna) gene and 454 sequencing of 16s rrna gene hypervariable regions (v1-v3 and v3-v5), were conducted on macroscopically disease-unaffected ileal biopsies collected from 52 ileal cd, 58 ulcerative colit ... | 2012 | 22719818 |
| unbalance of intestinal microbiota in atopic children. | playing a strategic role in the host immune function, the intestinal microbiota has been recently hypothesized to be involved in the etiology of atopy. in order to investigate the gastrointestinal microbial ecology of atopic disease, here we performed a pilot comparative molecular analysis of the faecal microbiota in atopic children and healthy controls. | 2012 | 22672413 |
| 454 pyrosequencing reveals a shift in fecal microbiota of healthy adult men consuming polydextrose or soluble corn fiber. | the relative contribution of novel fibers such as polydextrose and soluble corn fiber (scf) to the human gut microbiome and its association with host physiology has not been well studied. this study was conducted to test the impact of polydextrose and scf on the composition of the human gut microbiota using 454 pyrosequencing and to identify associations among fecal microbiota and fermentative end-products. healthy adult men (n = 20) with a mean dietary fiber (df) intake of 14 g/d were enrolled ... | 2012 | 22649263 |
| how can faecalibacterium prausnitzii employ riboflavin for extracellular electron transfer? | faecalibacterium prausnitzii is one of the most abundant commensal microbes in the human gut. it is an important supplier of butyrate to the colonic epithelium, and low numbers of faecalibacteria have been associated with severe inflammatory bowel disease. previous studies revealed that f. prausnitzii shuttles electrons extracellularly to oxygen in systems containing flavins and thiols. since this electron shuttling to oxygen strongly stimulates growth, the present studies were aimed at elucidat ... | 2012 | 22607129 |
| molecular-phylogenetic characterization of the microbiota in ulcerated and non-ulcerated regions in the patients with crohn's disease. | the dysbiosis of intestinal microbiota has been established in crohn's disease (cd), but the molecular characterization of this dysbiosis in chinese subjects with cd remains unclear. this study aims to investigate the predominant bacterial composition of the faecal and mucosal-associated microbiota in chinese cd patients using culture-independent techniques. | 2012 | 22529960 |
| increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome. | irritable bowel syndrome (ibs) is a multifactorial disease for which a dysbiosis of the gut microbiota has been described. bile acids (ba) could play a role as they are endogenous laxatives and are metabolized by gut microbiota. we compared fecal ba profiles and microbiota in healthy subjects (hs) and patients with diarrhea-predominant ibs (ibs-d), and we searched for an association with symptoms. | 2012 | 22356587 |
| comparison of bacterial quantities in left and right colon biopsies and faeces. | to compare quantities of predominant and pathogenic bacteria in mucosal and faecal samples. | 2012 | 22969206 |
| sensitivity of pathogenic and commensal bacteria from the human colon to essential oils. | the microbiota of the intestinal tract plays an important role in colonic health, mediating many effects of dietary components on colonic health and during enteric infections. in the context of the increasing incidence of antibiotic resistance in gut bacteria, complementary therapies are required for the prevention and treatment of enteric infections. here we report the potential application of essential oils (eo) and pure eo compounds to improve human gut health. nerolidol, thymol, eugenol and ... | 2012 | 22878397 |
| the antimicrobial action of chitosan, low molar mass chitosan, and chitooligosaccharides on human colonic bacteria. | antibacterial effect of chitooligosaccharides (cos) and low molar mass chitosans (lmwc) is considered as one of the most important characteristics of chitosan (cs) hydrolysates. here, we show the in vitro effect of different cos, lmwc, and cs on representative anaerobic bacteria isolated from human colon as a possibility of targeting modification of colonic microflora composition by supplementation of dietary cs products by humans. specific growth rate of seven selected nonpathogenic anaerobic b ... | 2012 | 22528310 |
| [high dosage methotrexate--pharmacokinetic surveillance and role of the nursing team]. | 2012 | 3635240 | |
| [high dosage methotrexate--pharmacokinetic surveillance and role of the nursing team]. | 2012 | 3635240 | |
| america's health policy agenda. | 2012 | 3509130 | |
| [diagnosis and treatment of fibrosing alveolitis]. | 2012 | 3603396 | |
| [diagnosis and treatment of fibrosing alveolitis]. | 2012 | 3603396 | |
| the acromioclavicular joint cyst. an unusual presentation of a rotator cuff tear. | an unusual presentation of a full-thickness tear of the rotator cuff is the acromioclavicular (ac) joint cyst. this is formed when glenohumeral joint fluid leaks through the full-thickness cuff tear and into a diseased ac joint, eventually distending the superior capsule. often, communication between the cyst and the glenohumeral joint can be demonstrated on shoulder arthrogram. it is essential to recognize that the presenting cyst is usually indicative of an underlying full-thickness rotator cu ... | 2012 | 3955947 |
| the acromioclavicular joint cyst. an unusual presentation of a rotator cuff tear. | an unusual presentation of a full-thickness tear of the rotator cuff is the acromioclavicular (ac) joint cyst. this is formed when glenohumeral joint fluid leaks through the full-thickness cuff tear and into a diseased ac joint, eventually distending the superior capsule. often, communication between the cyst and the glenohumeral joint can be demonstrated on shoulder arthrogram. it is essential to recognize that the presenting cyst is usually indicative of an underlying full-thickness rotator cu ... | 2012 | 3955947 |
| amniotic fluid prolactin, decidual prolactin content and decidual prolactin secretion into hypo-, iso-, and sodium chloride hyperosmotic media in vitro in pregnant diabetics at term. | this study evaluated in pregnant women with diabetes mellitus (dm) the prolactin (prl) concentration in amniotic fluid (a-prl), the initial decidual prl content (d-prl), and the decidual prl secretion (d-prl-s) in vitro into isosmotic (315 mmol/kg), hyperosmotic (426 mmol/kg) and hyposmotic (252 mmol/kg) media. decidual tissue was collected at term from 18 normal pregnancies and from 23 women with dm (white's classification: 7 of class a (without insulin treatment) and 16 of the classes b-f. twe ... | 2012 | 3551426 |
| amniotic fluid prolactin, decidual prolactin content and decidual prolactin secretion into hypo-, iso-, and sodium chloride hyperosmotic media in vitro in pregnant diabetics at term. | this study evaluated in pregnant women with diabetes mellitus (dm) the prolactin (prl) concentration in amniotic fluid (a-prl), the initial decidual prl content (d-prl), and the decidual prl secretion (d-prl-s) in vitro into isosmotic (315 mmol/kg), hyperosmotic (426 mmol/kg) and hyposmotic (252 mmol/kg) media. decidual tissue was collected at term from 18 normal pregnancies and from 23 women with dm (white's classification: 7 of class a (without insulin treatment) and 16 of the classes b-f. twe ... | 2012 | 3551426 |
| irritable bowel syndrome. | 2012 | 3459033 | |
| 86rubidium uptake in mononuclear leucocytes from offspring of essential hypertensive patients. | 2012 | 3459241 | |
| the evolution of antibiotic production and public health problems. | antibiotic evolution is closely paralleled by the evolution of bacterial resistance. prior to wide usage of penicillin g, resistance to beta-lactam antibiotics as a consequence of beta-lactamase production had been recognized, and has been an increasing clinical problem ever since. discovery of antibiotics other than beta-lactams, such as macrolides, tetracyclines and aminoglycosides, has also resulted in the eventual selection of bacteria resistant to these agents. synthesis of novel beta-lacta ... | 2012 | 3496977 |
| [complete hypopharynx reconstruction by 2 myocutaneous pectoral flaps]. | 2012 | 3431319 | |
| assessment of the hemodynamic response to single passive head up tilt by non-invasive methods in normotensive subjects. | the hemodynamic response to passive upright tilt in thirty-five normal subjects was assessed by combined electrocardiography, differentiated electrical impedance cardiography, phonocardiography and non-invasive blood pressure measurement. the increase in transthoracic impedance and decrease in estimated stroke volume were accompanied by a cardio-acceleratory and vasopressor response. the increase in heart rate did not compensate for the decrease in estimated stroke volume and the estimated cardi ... | 2012 | 3762269 |
| [determination of circulating igg, iga, igm, complement and immune complexes in lichen planus, behcet's disease and recurrent aphthae]. | 2012 | 3463491 | |
| [fixation in surgical orthodontics]. | 2012 | 3463488 | |
| patellar component dissociation in total knee arthroplasty. a report of two cases. | dissociation of the polyethylene from the metal baseplate of the patellar component in total knee arthroplasty (tka) occurred in two patients. analysis of intraoperative and postoperative photographs of the specimens indicates that "cold flow" of the polyethylene precedes dissociation from the metal baseplate. the diagnosis can be made on the basis of a pathogonomic metallic crepitus. | 2012 | 3342563 |
| osha standards. | 2012 | 3374607 | |
| your ce topic this month (no. 29). an update on natural and artificial sweeteners. | 2012 | 3351767 | |
| limitations of radionuclide ventriculography in the non-invasive diagnosis of coronary artery disease. a correlation with right heart haemodynamic values during exercise. | a consecutive series of 56 patients with chest pain but no evidence of previous myocardial infarction was prospectively studied by radionuclide ventriculography to determine the value of global and regional radionuclide indices in detecting coronary artery disease. the results were correlated with the clinical judgment of chest pain, the results of the exercise electrocardiogram, and the right heart haemodynamic measurements during exercise. as a result of the criteria for entry, the study group ... | 2012 | 4005082 |
| steroids in third molar surgery: a review. | 2012 | 3327741 | |
| [united nations' decade of the woman and measures in the area of occupational health]. | 2012 | 4092964 | |
| heterogeneity in expression of the bcr-abl fusion transcript in cml blast crisis. | the 9;22 philadelphia chromosome translocation in chronic myelogenous leukemia (cml) generates a bcr-abl fusion gene which codes for an aberrant 8-kb bcr-abl hybrid message. cml blast crisis cell lines display enhanced in vitro expression of this aberrant bcr-abl transcript when compared with fresh cml chronic phase cells. we directly compared in fresh patient samples the level of expression of the bcr-abl transcript in cml blast crisis versus chronic phase cells. all chronic phase patients disp ... | 2012 | 3312834 |
| cns peptides and regulation of gastric acid secretion. | 2012 | 3288091 | |
| [clinical experience of contraception in women over 40]. | 2012 | 3601187 | |
| a surfeit of fluoride? | 2012 | 3975596 | |
| changing clinical and laboratory concepts in inherited epidermolysis bullosa. | 2012 | 3281594 | |
| a brighter outlook. | 2012 | 3270440 | |
| detection of lens subluxation in pseudoexfoliation. | 2012 | 3261163 | |
| autoimmune mrl/lpr mice sera contain igg with interleukin 3-like activity. | the spleen cells, thymocytes, and bone marrow cells of autoimmune mrl/mp-lpr/lpr (mrl/lpr) mice do not constitutively produce interleukin 3 (il-3), but these mice had il-3-like activity in their sera. mrl/lpr sera supported the growth of the il-3-dependent cell lines fdc-p2 and da-1 but not the growth of il-2-dependent t-572 cells. this il-3-like activity increased with age. biochemical analysis of the mrl/lpr sera by anion-exchange chromatography, gel filtration on a superose 12 column, the bin ... | 2012 | 3257242 |
| mucosa-associated bacteria in two middle-aged women diagnosed with collagenous colitis. | to characterize the colon microbiota in two women histologically diagnosed with collagenous colitis using a culture-independent method. | 2012 | 22529692 |
| radiographic appearance of diffuse splenic hemangiomatosis. | the evaluation of splenomegaly in a patient with a consumptive coagulopathy included a liver-spleen scan, an abdominal sonogram, and an abdominal computed tomographic scan, which demonstrated an enlarged spleen with a diffuse parenchymal textural abnormality. a diffuse hemangiomatous pattern was present on splenic angiography. a splenectomy was performed and splenic hemangiomatosis was confirmed. the radiographic findings in this rare entity are presented and discussed. | 2012 | 3533697 |
| radiographic appearance of diffuse splenic hemangiomatosis. | the evaluation of splenomegaly in a patient with a consumptive coagulopathy included a liver-spleen scan, an abdominal sonogram, and an abdominal computed tomographic scan, which demonstrated an enlarged spleen with a diffuse parenchymal textural abnormality. a diffuse hemangiomatous pattern was present on splenic angiography. a splenectomy was performed and splenic hemangiomatosis was confirmed. the radiographic findings in this rare entity are presented and discussed. | 2012 | 3533697 |
| kidney transplantation. | the current status of bone marrow transplantation is reviewed. the diseases that are treatable with marrow transplantation, the basic transplant procedure, and the potential complications of marrow transplantation are discussed in detail. the future application of marrow transplantation to additional disease processes is considered. | 2012 | 3520894 |
| [dosed physical exercise in the early detection of cor pulmonale in chronic bronchitis patients]. | a combined study of some indices of external respiratory function (vital capacity, air flow peak rate and derivative values), physical exercise tolerance, ecg signs of hypertrophy of the right ventricle and pulmonary hypertension, microcirculation of the bulbar conjunctiva was performed in 125 patients with chronic bronchitis prior to and after submaximum bicycle ergometric testing. all indices in nonobstructive chronic bronchitis slightly changed as compared to controls. most of the patients wi ... | 2012 | 3603393 |
| [dosed physical exercise in the early detection of cor pulmonale in chronic bronchitis patients]. | a combined study of some indices of external respiratory function (vital capacity, air flow peak rate and derivative values), physical exercise tolerance, ecg signs of hypertrophy of the right ventricle and pulmonary hypertension, microcirculation of the bulbar conjunctiva was performed in 125 patients with chronic bronchitis prior to and after submaximum bicycle ergometric testing. all indices in nonobstructive chronic bronchitis slightly changed as compared to controls. most of the patients wi ... | 2012 | 3603393 |
| indium-111 leukocyte scanning for myocarditis. | 2012 | 3487222 | |
| evaluation of gait with multichannel electrical stimulation. | short, intensive multichannel electrical stimulation therapy was evaluated in 14 hemiplegics after stroke or head injury. the stimulation of the peroneal nerve, soleus, quadriceps, hamstring, gluteus maximus, and triceps brachii muscles with individually preprogrammed sequences was applied by surface electrodes at the beginning of gait rehabilitation. the patients started walking with the support of a therapist, gradually increased the walking distance and all reached independent ambulation with ... | 2012 | 3495792 |
| toward a rekindled professionalism. | 2012 | 3482501 | |
| subcellular localization of class i (a,b,c) and class ii (dr and dq) mhc antigens in jejunal epithelium of children with coeliac disease. | thin frozen sections of 11 jejunal biopsies from 10 children at different stages of coeliac disease were stained by immunofluorescence technique using a panel of anti-hla class i (a, b, c) and anti-hla class ii (dr and dq) monoclonal antibodies. on the epithelium of flattened mucosa, in contrast with control sections, the intensity of the labeling on the basolateral membranes with both anti-class i and class ii dr antibodies decreased strongly from the bottom to the upper part of the crypts, and ... | 2012 | 3540260 |
| infection control practices of state dental practitioners. | 2012 | 3474826 | |
| [clinical evaluation of famprofazone (apagan, liquid type) in oral surgery]. | 2012 | 3506950 | |
| [a case report of death from neuroleptic malignant syndrome]. | 2012 | 3411805 | |
| glass is detectable on plain radiographs. | 2012 | 3416265 | |
| the fluorescence properties of ortho aminobenzoate anesthetics in define solvents and phospholipid vesicles. | 2012 | 3406128 | |
| [longevity]. | 2012 | 3642160 | |
| sub-acute cutaneous lupus erythematosus and gluten sensitive enteropathy. | 2012 | 3395570 | |
| intravenous prostacyclin in acute nonhemorrhagic stroke: a placebo-controlled double-blind trial. | the therapeutic efficacy of prostacyclin in nonhemorrhagic cerebral infarction was assessed in a placebo-controlled double-blind trial. a total of 80 patients with stroke onset within 24 hours were randomized into placebo (37 patients) and prostacyclin (43 patients) groups. demographic data and risk factors were comparable. patients in the prostacyclin group received a continuous i.v. infusion of prostacyclin at an average rate of 8.5 ng/kg/min for an average of 64 hours. the placebo group recei ... | 2012 | 3551212 |
| intravenous prostacyclin in acute nonhemorrhagic stroke: a placebo-controlled double-blind trial. | the therapeutic efficacy of prostacyclin in nonhemorrhagic cerebral infarction was assessed in a placebo-controlled double-blind trial. a total of 80 patients with stroke onset within 24 hours were randomized into placebo (37 patients) and prostacyclin (43 patients) groups. demographic data and risk factors were comparable. patients in the prostacyclin group received a continuous i.v. infusion of prostacyclin at an average rate of 8.5 ng/kg/min for an average of 64 hours. the placebo group recei ... | 2012 | 3551212 |
| [a clinical study of the complete zygo-buccal-flange denture]. | 2012 | 3463487 | |
| right-handed longevity not so sinister after all? | 2012 | 3374611 | |
| [antinuclear antibodies in the blood of patients with otosclerosis]. | 2012 | 3487838 | |
| [progress in science and technology, medicine and the law]. | 2012 | 3363416 | |
| [therapy of sleep apnea with an evening dose of retard theophylline (euphylong)]. | 2012 | 3325963 | |
| total cholesterol and high density lipoprotein cholesterol levels in populations differing in fat and carbohydrate intake. | this paper reviews epidemiological studies on the relationship between diet and high density lipoproteins (hdl), with emphasis on the authors' studies of boys and men from different countries and with different dietary habits. sera were collected from boys (ages 7 to 9 years) and men (ages 33 to 48 years) in 20 countries, and these were analyzed in one standardized laboratory. in boys, total and hdl cholesterol changed in parallel, from low values in populations in developing countries with low- ... | 2012 | 3318781 |
| incidence and distribution of immunocytes in the murine oral mucosa. | 2012 | 3318288 |