Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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gender-specific improvements in outcome 1 and 2 years after major trauma. | the study aim was to evaluate patient progress over time, given the limited knowledge available on gender-dependent longer-term outcomes after major trauma. | 2019 | 30691830 |
equestrian-related injuries, predictors of fatalities, and the impact on the public health system in sweden. | horse riding is a popular activity but has also been found to lead to many injuries and even fatalities. no reduction in the numbers of those being admitted to hospital for equestrian-related injuries have been seen in sweden in recent years. the aim of this work was to examine injuries, fatalities, and predictors of fatalities in equestrian-related activities and to investigate the cost of these injuries to the public health system. | 2019 | 30690221 |
economic evaluation of combining pharmaco- and behavioral therapies for smoking cessation in an occupational medicine setting. | to estimate the budget impact (bi) of funding pharmaco+behavioral therapies for smoking cessation from an employer perspective. | 2019 | 30688765 |
hospitalisations with burns in children younger than five years in portugal, 2011-2015. | paediatric population still represents a high burden of hospitalisations among burns inpatients. children under five years old have a distinct aetiology distribution comparing to other age groups, representing in portugal a fifth of all hospitalisations with burns. we aimed to describe the demographic and clinical burden of burns requiring hospitalization, as well as hospitalization charges, among this age group in portugal. | 2019 | 30686698 |
lung effects of 7- and 28-day inhalation exposure of rats to emissions from 1st and 2nd generation biodiesel fuels with and without particle filter - the fuelhealth project. | increased use of 1st and 2nd generation biofuels raises concerns about health effects of new emissions. we analyzed cellular and molecular lung effects in fisher 344 rats exposed to diesel engine exhaust emissions (dee) from a euro 5-classified diesel engine running on b7: petrodiesel fuel containing 7% fatty acid methyl esters (fame), or shb20 (synthetic hydrocarbon biofuel): petrodiesel fuel containing 7% fame and 13% hydrogenated vegetable oil. the fisher 344 rats were exposed for 7 consecuti ... | 2019 | 30685595 |
comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the united kingdom, italy, and denmark. | the objective of this study was to estimate the cost impact of neodymium-doped yttrium aluminum garnet (nd:yag) laser capsulotomy and its complications due to single-piece acrylic monofocal intraocular lenses (iols) in the healthcare setting of united kingdom, italy, and denmark. | 2019 | 30679902 |
environmental public health risks in european metropolitan areas within the euro-healthy project. | urban areas in europe are facing a range of environmental public health challenges, such as air pollution, traffic noise and road injuries. the identification and quantification of the public health risks associated with exposure to environmental conditions is important for prioritising policies and interventions that aim to diminish the risks and improve the health of the population. with this purpose in mind, the euro-healthy project used a consistent approach to assess the impact of key envir ... | 2019 | 30678019 |
cost-effectiveness analysis of the sapien 3 tavi valve compared with surgery in intermediate-risk patients. | transcatheter aortic valve implantation (tavi) has become the therapy of choice for treating severe aortic stenosis in patients at high-risk for surgery or where it is considered too risky to attempt. this uptake varies across geographies however, and its cost or value has frequently been cited as the reason for this. we sought to evaluate the potential cost and clinical impact of tavi in intermediate risk patients from a french collective perspective. | 2019 | 30547704 |
economic evaluation of trifluridine and tipiracil hydrochloride in the treatment of metastatic colorectal cancer in greece. | to evaluate the cost-effectiveness of trifluridine and tipiracil hydrochloride (ftd/tpi) compared with best supportive care (bsc) or regorafenib for the treatment of patients with metastatic colorectal cancer who have been previously treated with or are not considered candidates for available therapies including fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapies, anti-vegf agents and anti-egfr agents in greece. | 2019 | 30547679 |
cost-effectiveness of second-line treatments for metastatic renal-cell carcinoma. | to assess the pharmacologic costs of second-line treatments for metastatic renal-cell cancer (mrcc). | 2019 | 30545674 |
increasing potency and price of cannabis in europe, 2006-16. | to quantify changes in (i) potency (concentration of δ9 -tetrahydrocannabinol; %thc), (ii) price (euros/g of cannabis) and (iii) value (mg thc/euro) of cannabis resin and herbal cannabis in europe. | 2019 | 30597667 |
assessing the influence of boundary conditions, driving behavior and data analysis methods on real driving co2 and nox emissions. | the need to verify vehicle emissions in real world operation led to the implementation of real driving emissions (rde) test procedures, effective since september 2017 for new euro 6 cars following the commission regulation (eu) 2016/427, which defines the rde test conditions and data analysis methods to allow representative results. main factors addressed by the regulation include the share of driving operation, ambient temperature range, altitude and elevation difference. however, rde is still ... | 2019 | 30583183 |
non-leukemic pediatric mixed phenotype acute leukemia/lymphoma: genomic characterization and clinical outcome in a prospective trial for pediatric lymphoblastic lymphoma. | rare cases of hematological precursor neoplasms fulfill the diagnostic criteria of mixed phenotype acute leukemia (mpal), characterized by expression patterns of at least two hematopoietic lineages, for which a highly aggressive behavior was reported. we present a series of 11 pediatric non-leukemic mpal identified among 146 precursor lymphoblastic lymphomas included in the prospective trial euro-lbl 02. paraffin-embedded biopsies of 10 cases were suitable for molecular analyses using oncoscan a ... | 2019 | 30578714 |
the future of healthcare has arrived: who dares take up the challenge? | according to the euro health consumer index, the dutch healthcare system is the champion of europe. yet we are living for longer, prosperity is increasing and the population is growing. if we do not continue to adjust our healthcare system to these trends, medical expenses in the netherlands will double to € 174 billion (in 2040). we are also facing job market difficulties in healthcare. we risk a shortfall of 125 thousand employees in 2022. it is therefore time to restructure healthcare. not to ... | 2019 | 30536147 |
once-weekly semaglutide versus once-daily liraglutide for the treatment of type 2 diabetes: a long-term cost-effectiveness analysis in estonia. | once-weekly semaglutide is a novel glucagon-like peptide-1 (glp-1) analogue for the treatment of type 2 diabetes that was associated with greater reductions in glycated hemoglobin (hba1c) and body mass index (bmi) versus once-daily glp-1 analogue liraglutide in a recent network meta-analysis (nma). the aim of the present study was to assess the long-term cost-effectiveness of once-weekly semaglutide 1 mg versus liraglutide 1.2 mg in estonia. | 2019 | 30535837 |
mortality in the visegrad countries from the perspective of socioeconomic inequalities. | large socioeconomic inequalities in health are still present in the central europe. the aim was to explore socioeconomic inequalities in mortality in visegrad countries-the czech republic, hungary, poland and slovakia (v4), by three different socioeconomic indicators (unemployment, risk of poverty/social exclusion, education). the study was conducted within the h2020 euro-healthy project. | 2019 | 30535783 |
responses of a resistive soot sensor to different mono-disperse soot aerosols. | since 2011, the euro 5b european standard limits the particle number (pn) emissions in addition to the particulate mass (pm) emissions. new thermal engine equipped vehicles also have to auto-diagnose their own particulate filter (diesel particulate filter or gasoil particulate filter) using on-board diagnostic (obd) sensors. accumulative resistive soot sensors seem to be good candidates for pm measurements. the aim of this study is to bring more comprehension about soot microstructures construct ... | 2019 | 30744083 |
influence of strategic planning on product marketing and health service orientation of community pharmacies-a national survey in finland. | the aim of this study was to explore pharmacy owners' views on the strategic development of community pharmacies, particularly how strategic planning at the pharmacy level influences on product marketing and health service orientation of individual community pharmacies. the study was carried out as a national cross-sectional e-mail survey sent to all privately-owned finnish community pharmacies (n = 581) in march 2013 (response rate 34%, n = 198). the pharmacy owners were asked about their strat ... | 2019 | 30808534 |
patient-reported outcomes of adults with congenital heart disease from eight european countries: scrutinising the association with healthcare system performance. | inter-country variation in patient-reported outcomes of adults with congenital heart disease has been observed. country-specific characteristics may play a role. a previous study found an association between healthcare system performance and patient-reported outcomes. however, it remains unknown which specific components of the countries' healthcare system performance are of importance for patient-reported outcomes. | 2019 | 30808198 |
a study on the co2 and nox emissions performance of euro 6 diesel vehicles under various chassis dynamometer and on-road conditions including latest regulatory provisions. | the current study presents a detailed analysis of the gaseous emissions, focusing on co2 and nox, of diesel vehicles under several operating conditions. an assessment is also made on the impact and effectiveness of the real driving emissions (rde) test, which is mandatory by the european union (eu) type approval regulation for passenger cars since september 2017. the method followed comprises emissions measurement tests on three euro 6 diesel vehicles, under laboratory and various on-road operat ... | 2019 | 30798242 |
"in the street they're real, in a picture they're not": constructions of children and childhood among users of online child sexual exploitation material. | research about online child sexual exploitation material (csem) users focuses on psychological assessments, demographics, motivations, and offending rates. little is known about their understandings of children in csem. | 2019 | 30797119 |
numerical simulation of dynamic mechanical properties of concrete under uniaxial compression. | based on the base force element method (bfem), the dynamic mechanical behavior of concrete under uniaxial compression loading at different strain rates is investigated. the concrete can be considered as a three-phase composite material composed of aggregate, cement mortar, and interfacial transition zone (itz) on the meso-level. a two-dimensional random aggregate model is generated by the monte carlo method. a multi-linear two-dimensional damage model is applied to describe the damage properties ... | 2019 | 30791665 |
bunias erucago l.: glucosinolate profile and in vitro biological potential. | bunias erucago belongs to the brassicaceae family, which represents a forgotten crop of the euro-mediterranean area. the aim of the present study was to determine the glucosinolate profile in different plant parts and biological properties (antioxidant, anticholinesterase, and cytotoxic activities) of the isolates containing glucosinolate breakdown products. the chemical profiles were determined by using hplc-pda-ms/ms of desulfoglucosinolates and gc-ms of glucosinolate degradation products. the ... | 2019 | 30791395 |
high-resolution characterization of 12 classical and non-classical hla loci in southern brazilians. | the human leukocyte antigen (hla) are the most polymorphic genes in the human genome. because of their importance for antigen recognition, hla molecules play a central role in host defense and graft rejection upon transplantation. the aim of this study was to characterize allelic diversity of the classical hla genes hla-a, -b, -c, -dra, -drb1, -dqa1, -dqb1, -dpa1, -dpb1, and the non-classical class i genes hla-e, -f and -g at high-resolution for a population of predominantly european ancestry fr ... | 2019 | 30740929 |
impact of post-traumatic stress symptoms on the health-related quality of life in a cohort study with chronically critically ill patients and their partners: age matters. | survivors of an acute critical illness with continuing organ dysfunction and uncontrolled inflammatory responses are prone to become chronically critically ill. as mental sequelae, a post-traumatic stress disorder and an associated decrease in the health-related quality of life (qol) may occur, not only in the patients but also in their partners. currently, research on long-term mental distress in chronically critically ill patient-partner dyads, using appropriate dyadic analysis strategies (pat ... | 2019 | 30736830 |
cost-effectiveness of continuous subcutaneous insulin infusion versus multiple daily injections in patients with poorly controlled type 2 diabetes in finland. | although primarily utilized in type 1 diabetes, continuous subcutaneous insulin infusion (csii) represents a useful treatment alternative for patients with type 2 diabetes who are unable to achieve good glycemic control despite optimization of multiple daily injections (mdi). the aim of the analysis reported here was to investigate the long-term cost-effectiveness of csii versus mdi in type 2 diabetes patients with poor glycemic control in finland. | 2019 | 30730036 |
cost-effectiveness of trans-nasal endoscopic sphenopalatine artery ligation vs arterial embolisation for intractable epistaxis: long-term analyses. | trans-nasal endoscopic sphenopalatine artery ligation (tespal) and endovascular arterial embolisation both provide excellent success rates for intractable epistaxis. recent economic models suggest that tespal could be a cost-saving strategy. our main aim was to perform cost-effectiveness analyses on tespal compared with embolisation to treat patients with epistaxis. | 2019 | 30720918 |
a report on the marrakech international women's cancer days: dialogs and implications. | the marrakechinternational women's cancer days showcased a first-time international meeting of healthcare professionals worldwide to discuss, over the course of 3 days, aspects of public health, prevention, and treatment of gynecological cancers in the arabic region. the focus was particularly on promoting globally sustainable research initiatives. the event was a joint initiative organized by the gynecological cancer intergroup and the pan-arabian research society of gynecological oncology. the ... | 2019 | 30718317 |
economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using markov models. | to determine the economic impact of three drugs commonly involved in potentially inappropriate prescribing (pip) in adults aged ≥65 years, including their adverse effects (aes): long-term use of non-steroidal anti-inflammatory drugs (nsaids), benzodiazepines and proton pump inhibitors (ppis) at maximal dose; to assess cost-effectiveness of potential interventions to reduce pip of each drug. | 2019 | 30705233 |
anorexia is independently associated with decreased muscle mass and strength in community dwelling older adults. | we aimed to investigate the association between anorexia and sarcopenia in community dwelling older adults. | 2019 | 30697631 |
epidemiology, clinical features and management of patients presenting to european emergency departments with acute cocaine toxicity: comparison between powder cocaine and crack cocaine cases. | objective: to analyse the epidemiology, clinical picture and emergency department (ed) management of a large series of patients who presented to european eds after cocaine consumption, comparing data from powder (c1 group) and crack (c2 group) consumers. methods: between october 2013 and december 2016, the euro-den plus registry recorded 17,371 consecutive acute recreational drug toxicity presentations to 22 eds in 14 european countries. epidemiological and demographic data, co-ingestion of alco ... | 2019 | 30696283 |
erratum for euro surveill. 2019;24(1). | 2019 | 30670141 | |
effectiveness and cost-effectiveness of a yoga-based cardiac rehabilitation (yoga-care) program following acute myocardial infarction: study rationale and design of a multi-center randomized controlled trial. | cardiac rehabilitation (cr) is a standard treatment for secondary prevention of acute myocardial infarction (ami) in high income countries (hics), but it is inaccessible to most patients in india due to high costs and skills required for multidisciplinary cr teams. we developed a low-cost and scalable cr program based on culturally-acceptable practice of yoga (yoga-care). in this paper, we report the rationale and design for evaluation of its effectiveness and cost-effectiveness. | 2019 | 30661847 |
fetal fibronectin test for threatened preterm delivery 48h after admission: cost-effectiveness study. | the aim of this work was to assess the cost-effectiveness of the fetal fibronectin (ffn) test at 48 h after admission for threatened preterm delivery to promote early discharge. | 2019 | 30660942 |
abc (atrial fibrillation better care) pathway and healthcare costs in atrial fibrillation: the athero-af study. | the atrial fibrillation better care (abc) pathway has been proposed to streamline patient management in an integrated, holistic manner. compliance to abc resulted in lower incidence of cardiovascular events, but its impact on health-related costs has not been evaluated. | 2019 | 30659810 |
can mentorship improve laboratory quality? a case study from influenza diagnostic laboratories in southeast europe. | strengthening the quality of laboratory diagnostics is a key part of building global health capacity. in 2015, the centers for disease control and prevention (cdc), the southeast european center for surveillance and control of infectious diseases (secid), who european regional office (who euro) and american public health laboratories (aphl) collaborated to address laboratory quality training needs in southeast europe. together, they developed a quality assurance (qa) mentorship program for six n ... | 2019 | 30658627 |
do dutch dentists extract monopoly rents? | we exploit lottery-determined admission to dental school to estimate the payoffs to the study of dentistry in the netherlands. using data from up to 22 years after the lottery, we find that in most years after graduation dentists earn around 50,000 euros more than they would earn in their next-best profession. the payoff is larger for men than for women but does not vary with high school gpa. the large payoffs cannot be attributed to longer working hours, larger investments while studying (oppor ... | 2019 | 30658150 |
prevalence of abnormal alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three european memory clinic samples. | subjective cognitive decline (scd) in cognitively unimpaired older individuals has been recognized as an early clinical at-risk state for alzheimer's disease (ad) dementia and as a target population for future dementia prevention trials. currently, however, scd is heterogeneously defined across studies, potentially leading to variations in the prevalence of ad pathology. here, we compared the prevalence and identified common determinants of abnormal ad biomarkers in scd across three european mem ... | 2019 | 30654834 |
associations of electric shock and extremely low-frequency magnetic field exposure with the risk of amyotrophic lateral sclerosis. | we explored the associations of occupational exposure to extremely low-frequency magnetic fields (elf-mf) and electric shocks with the risk of amyotrophic lateral sclerosis (als) in a pooled case-control study (european multidisciplinary als network identification to cure motor neurone degeneration (euro-motor)) of data from 3 european countries. als patients and population-based controls were recruited in ireland, italy, and the netherlands between 2010 and 2015. lifetime occupational and lifes ... | 2019 | 30649156 |
authors' correction for euro surveill. 2018;23(50). | 2019 | 30646976 | |
discrimination between obstructive coronary artery disease and cardiac syndrome x in women with typical angina and positive exercise test; utility of cardiovascular risk calculators. | introduction: nearly 40% of women with typical angina and a positive exercise tolerance test (ett) have normal or near normal coronary angiography (cag) labeled as cardiac syndrome x (csx). objective: we performed this study to evaluate the power of common cardiovascular risk calculators to distinguish patients with csx from those with coronary artery disease (cad). methods: 559 women participated in the study. three risk scores, including (1) newly pooled cohort equation of american college of ... | 2019 | 30646563 |
a low-cost metal-free photocatalyst based on black phosphorus. | an efficient metal-free photocatalyst composed of black phosphorus (bp) and graphitic carbon nitride (cn) is prepared on a large scale by ball milling. using economical urea and red phosphorus (rp) as the raw materials, the estimated materials cost of bp/cn is 0.235 euro per gram. the bp/cn heterostructure shows efficient charge separation and possesses abundant active sites, giving rise to excellent photocatalytic h2 evolution and rhodamine b (rhb) degradation efficiency. without using a co-cat ... | 2019 | 30643723 |
chimeric vaccine strain of type o foot-and-mouth disease elicits a strong immune response in pigs against me-sa and sea topotypes. | foot-and-mouth disease (fmd) is an acute infectious disease occurring in cloven-hoofed animals. there are many variations of the virus, making it difficult to protect against the various strains with one virus vaccine. the immunogenicity has generally been evaluated in pigs using neutralizing antibodies to determine the protection level against foot-and-mouth disease virus type o. therefore, the vaccine from the chimeric vaccine strain of me-sa (vp4, vp2, and vp3) and sea (vp1) topotypes develop ... | 2019 | 30642587 |
[specific immunotherapies in the treatment of cancers]. | the offer of anti-cancer drugs has recently been disrupted by the introduction of checkpoint inhibitors on the market. currently, one anti-ctla-4, two anti-pd-1 and two anti-pd-l1 are authorized in the european union, in seven different types of cancer. the clinical development of these therapies is still in full swing: in july 2017, more than 1 500 clinical trials were evaluating anti-pd-1, anti-pd-l1 and anti-ctla-4 drugs in about twenty different locations and this number continues to increas ... | 2019 | 30638899 |
emergencies related to recreational drug abuse in spain compared to emergencies attended in 3 european areas. | to analyze epidemiologic, clinical, and care characteristics in cases in which patients came to 2 spanish emergency departments (eds) with symptoms caused by recreational drug abuse. to compare the characteristics with those reported for other areas of europe. | 2019 | 30638341 |
[economic evaluation of the alfred 60/ast device implantation for bacterial growth detection with automatic sewing machine]. | it is becoming increasingly necessary to automatize screening of urine samples to culture at microbiology laboratories. our objective was to estimate the budget threshold from which the alfred 60/ast device would be profitable for our hospital. | 2019 | 30630308 |
retrospective electrocardiography-gated real-time cardiac cine mri at 3t: comparison with conventional segmented cine mri. | segmented cardiac cine magnetic resonance imaging (mri) is the gold standard for cardiac ventricular volumetric assessment. in patients with difficulty in breath-holding or arrhythmia, this technique may generate images with inadequate quality for diagnosis. real-time cardiac cine mri has been developed to address this limitation. we aimed to assess the performance of retrospective electrocardiography-gated real-time cine mri at 3t for left ventricular (lv) volume and mass measurement. | 2019 | 30627027 |
number of remaining teeth and health-related quality of life: the korean national health and nutrition examination survey 2010-2012. | with the euro-qol-5 dimension (eq-5d) system, we investigated the relationship between the number of remaining teeth and qol using data from the korean national health and nutrition examination survey (knhanes), 2010-2012. a total of 17,417 participants, more than 19 years old, were finally included in this study (men = 7394 and women = 10,023). through this study, we have discovered that the remaining teeth affect overall health and that the fewer number of them may indicate a lower quality of ... | 2019 | 30626402 |
in-vehicle airborne fine and ultra-fine particulate matter exposure: the impact of leading vehicle emissions. | airborne particulate matter (pm) concentrations inside vehicle cabins are often extremely high compared to background levels. the present study was motivated by the fact that in the last few decades, the implementation of new emission standards has led to the reduction of vehicle particle emissions. this study addresses for the first time the relationship between leading vehicle (lv) emissions and in-cabin pm exposure levels in the immediately following vehicle (henceforth called the study vehic ... | 2019 | 30622065 |
seasonal influenza in spain: clinical and economic burden and vaccination programmes. | a literature review has been carried out to analyse the clinical burden, the economic impact of influenza and the efficiency of influenza vaccination programmes in spain. the average incidence rate of influenza in spain is 2,069 cases per 100,000 inhabitants, with a significant impact on mortality and a reduction of health-related quality of life. in terms of its associated costs, influenza causes a significant burden on primary care, hospitals, treatments and absences from work every year, whic ... | 2019 | 30621906 |
costs of clinical trials with anticancer biological agents in an oncologic italian cancer center using the activity-based costing methodology. | the aim of the present study was to assess the estimated "per patient" total cost for a single oncologic italian cancer center participating in a multicenter clinical trial with new anticancer biological agents using the activity-based costing (abc) methodology. | 2019 | 30620767 |
hepatitis a incidence, seroprevalence, and vaccination decision among msm in amsterdam, the netherlands. | several outbreaks of hepatitis a virus (hav) were recently documented among men who have sex with men (msm) in europe. we investigated the hav incidence among msm in amsterdam, the netherlands; and hav seroprevalence and hav vaccination decision among msm visiting the sexually transmitted infection (sti) clinic in amsterdam. | 2019 | 30992222 |
cost of sickness absenteeism during seasonal influenza outbreaks of medium intensity among health care workers. | this study aims to estimate the economic costs of sickness absenteeism of health care workers in a large italian teaching hospital during the seasonal flu periods. a retrospective observational study was performed. the excess data of hospital's sickness absenteeism during three seasonal influenza periods (2010/2011; 2011/2012; 2012/2013) came from a previous study. the cost of sickness absenteeism was calculated for six job categories: medical doctor, technical executive (i.e., pharmacists); nur ... | 2019 | 30832264 |
fluorescent scanning thermal microscope based on a blu-ray optical head to measure thermal diffusivity of radioactive samples. | over the life of nuclear fuel, inhomogeneous structures develop, negatively impacting thermal properties. new fuels are under development but require more accurate knowledge of how the properties change to model performance and determine safe operational conditions. measurement systems capable of microscopic thermal transport measurements and low cost are necessary to measure these properties and integrate into hot cells where electronics are likely to fail during fuel investigation. this projec ... | 2019 | 30831718 |
impact of birthweight on health-care utilization during early childhood - a birth cohort study. | comprehensive data are needed to evaluate the burden of low birthweight. analysis of routine data on health-care utilization during early childhood were used to test the hypothesis that infants with low birthweight have (i) increased inpatient health-care utilization, (ii) higher hospital costs and (iii) different morbidity pattern in early childhood when compared with normal birthweight infants. | 2019 | 30823910 |
migrant workers from the eastern-mediterranean region and occupational injuries: a retrospective database-based analysis from north-eastern italy. | the month of ramadan is the ninth month of the islamic lunar calendar, and, according to the islamic tradition, it coincides with the month when the noble koran/qur'an began to be revealed. in recent years, concerns about the potentially negative health effects of ramadan fasting and the risks of work-related injuries have increased in western european (euro) countries. in the present study, we performed a retrospective database-based analysis assessing the impact of ramadan fasting on occupatio ... | 2019 | 30823571 |
management preferences in ecmo mode for congenital diaphragmatic hernia. | the purpose of this study was to identify management preferences that may exist in the care of infants with cdh receiving ecmo with emphasis on vv-ecmo. | 2019 | 30786989 |
people who inject drugs remain hard-to-reach population across all hiv continuum stages in central, eastern and south eastern europe - data from euro-guidelines in central and eastern europe network. | inadequate hiv care for hard-to-reach populations may result in failing the unaids 90-90-90 goal. therefore, we aimed to review the hiv continuum of care and hard-to-reach populations for each step of the continuum in central, eastern and south eastern europe. | 2019 | 30786803 |
euro mps back wider use of medical cannabis amid call for more research. | 2019 | 30777854 | |
college alcohol beliefs: measurement invariance, mean differences, and correlations with alcohol use outcomes across sociodemographic groups. | undergraduate students who believe that alcohol plays a central role in college life are prone to drink more frequently, in larger quantity, and experience more drinking problems. the college life alcohol salience scale (class) measures individuals' college-related alcohol beliefs but has been used predominantly in euro american and freshman student samples. emerging research suggests mean differences in college alcohol beliefs by gender and years in college, and measurement nonequivalence acros ... | 2019 | 30777775 |
cost-effectiveness comparison of pneumococcal conjugate vaccines in turkish children. | the 13-valent pneumococcal conjugate vaccine (pcv13) is used for universal infant vaccination in turkey. | 2019 | 30776766 |
regulating particle number measurements from the tailpipe of light-duty vehicles: the next step? | light-duty vehicle emission regulation in the european union requires the dilution of the whole exhaust in a dilution tunnel with constant volume sampling prior to emission measurements. this methodology avoids measurement uncertainties associated with direct raw exhaust emission measurements from the tailpipe, such as exhaust flow determination, exhaust flow pressure pulsations, differences in the response time between exhaust flow and instrument signals, or their misalignment. transfer tubes c ... | 2019 | 30769183 |
health benefits of physical activity related to an urban riverside regeneration. | the promotion of physical activity through better urban design is one pathway by which health and well-being improvements can be achieved. this study aimed to quantify health and health-related economic impacts associated with physical activity in an urban riverside park regeneration project in barcelona, spain. we used data from barcelona local authorities and meta-analysis assessing physical activity and health outcomes to develop and apply the "blue active tool". we estimated park user health ... | 2019 | 30764538 |
scorecard for spina bifida research, prevention, and policy: score analysis by human development index and who region. | the people and organizations united for spina bifida and hydrocephalus (push!) global alliance created scorecards to rate country-level performance on spina bifida, including folate status among women of reproductive age; birth prevalence and mortality associated with spina bifida; prevention strategies; access to care; and the country's engagement in the un convention on the rights of persons with disabilities. a total of 187 countries were examined based on a criteria-based scoring system repr ... | 2019 | 30763626 |
price competition and reimbursement of biosimilar granulocyte-colony stimulating factor in hungary. | objectives: we analyzed the bid approach of the hungarian national health insurance fund administration (nhifa) based on the results of two consecutive bids on colony stimulating factor (csf).methods: the hungarian nhifa database was used to analyze the changes in the number of patients treated with csf and reimbursement paid by nhifa, 12 months preceding and following the bids.results: 13,974 patients received granulocyte-csf treatment during 12 months prior to bidding. a 4.5% decrease (13,352) ... | 2019 | 30763134 |
assessment of euro 5 diesel vehicle nox emissions by laboratory and track testing. | the volkswagen scandal has promoted experimental campaigns worldwide aimed to assess the real exhaust emissions of in-use vehicles. attention has been paid to diesel vehicle nox emissions that are much higher than legislative type-approval limits. this paper analysed exhaust emissions of a fleet of ten euro 5 diesel vehicles. nox emissions were measured during laboratory and track testing. in both cases, the type-approval test was carried out with cold and warm starts. moreover, in the laborator ... | 2019 | 30762182 |
a perception on genome-wide genetic analysis of metabolic traits in arab populations. | despite dedicated nation-wide efforts to raise awareness against the harmful effects of fast-food consumption and sedentary lifestyle, the arab population continues to struggle with an increased risk for metabolic disorders. unlike the european population, the arab population lacks well-established genetic risk determinants for metabolic disorders, and the transferability of established risk loci to this population has not been satisfactorily demonstrated. the most recent findings have identifie ... | 2019 | 30761081 |
pediatric meningococcocal meningitis in the acute phase: how much does it cost? | meningococcal meningitis (mm) is known to be responsible of high cost for the public health administration. aim of the work is to calculate the costs for the hospitalization of pediatric patients affected by mm. | 2019 | 30760306 |
[tremendous increase of home care in ventilated and tracheostomized patients - reasons, consequences, solutions]. | since 2005, invasive long-term ventilation in germany has increased significantly from around 1000 to 20 000 patients in germany. due to complex home care, the health care system incurs additional costs of around 4 billion euros per year. in addition, in the last 2 - 3 years more tracheostomized patients have been discharged home without ventilation (usually after stroke), and they receive the same complex home care. these patients have almost never been given the chance of a professional weanin ... | 2019 | 30759476 |
refractory lupus nephritis: a survey. | 'refractory lupus nephritis' is a frequently used term but poorly defined. we conducted a survey among nephrologists and rheumatologists to spot the diversity of perceptions of this term and to better understand the clinical practice related to 'refractory lupus nephritis'. a total of 145 questionnaires completed by lupus nephritis experts were available for analysis, of which 52% were nephrologists, 34% rheumatologists, and 13% internists. response to induction treatment was mostly assessed aft ... | 2019 | 30755142 |
keep your head up-correlation between visual exploration frequency, passing percentage and turnover rate in elite football midfielders. | statistical analysis of real in-game situations plays an increasing role in talent identification and player recruitment across team sports. recently, visual exploration frequency (vef) in football has been discussed as being one of the important performance-determining parameters. however, until now, vef has been studied almost exclusively in laboratory settings. moreover, the vef of individuals has not been correlated with performance parameters in a statistically significant number of top-lev ... | 2019 | 31174322 |
healthcare costs of the satisfaction and adherence to copd treatment (sat) study follow-up. | chronic obstructive pulmonary disease (copd) is characterised by recurring exacerbations. we estimated the costs of healthcare resources for copd management funded by the italian national healthcare service (inhs) for one year. | 2019 | 31174106 |
benchmarking belgian crt practice against the rest of europe: insights from the esc-crt survey ii. | this subanalysis of the euro-crt survey ii specifically focus on belgian practice for crt implantation. it explores belgian adherence with the guidelines but also benchmark crt practice in belgium against the other european countries. overall, belgian management of crt implantation is performed with great agreement with guidelines. this report could be used to provide guidance for both practical and economical approaches. | 2019 | 31190617 |
implementation of point-of-care testing and a temporary influenza ward in a dutch hospital. | the seasonal influenza epidemic poses a significant burden on hospitals, both in terms of capacity and costs. beds that are occupied by isolated influenza patients result in hospitals temporary being closed to admissions and elective operations being cancelled. improving hospital and emergency department (ed) patient flow during the influenza season could solve these problems. microbiological point-of-care-testing (poct) could reduce unnecessary patient isolation by providing a positive/negative ... | 2019 | 31012428 |
the charismatic leadership of the ecb presidency: a language-based analysis. | there is little doubt that the european central bank (ecb), and in particular its presidency, has taken the lead in tackling the euro crisis. but can this leadership be also characterised as charismatic? this article answers the question by focusing on language - a key component as well as a reliable indicator of charisma. by means of a software-assisted content analysis of the entire corpus of ecb presidential speeches, it is found that the crisis has indeed led to the emergence of the bank's p ... | 2019 | 31007351 |
costs of irritable bowel syndrome in european countries with universal healthcare coverage: a meta-analysis. | to provide an overall estimate of the direct, indirect and total costs of irritable bowel syndrome (ibs) for the adult population of the european countries with universal healthcare coverage. | 2019 | 31002149 |
association between income and control of cardiovascular risk factors after acute coronary syndromes: an observational study. | the role of income in cardiovascular disease prevention after an acute coronary syndrome (acs) remains unclear. we aimed to assess the association between income and control of cardiovascular risk factors one year after an acs in a country with universal health insurance. | 2019 | 30994923 |
[nutritional status regarding the quality of life and sleep pattern in community-dwelling older adults with cognitive dysfunction]. | aim: to establish and to analyze a possible relationship between nutritional status, sleep pattern and quality of life in a sample of patients with cognitive dysfunction. participants and method: an observational, descriptive study of a group of cases with a sample constituted of 48 elderly individuals (aged 65 or over) who agreed to participate in the study and lived in valencia (spain). euroqol (eq-5d), oviedo sleep questionnaire (osq), mini mental state de folsteisn (mmse) and mini nutritiona ... | 2019 | 30868911 |
cancer patients' use of complementary and alternative medicine in sweden: a cross-sectional study. | access to and advice on complementary and alternative medicine (cam) are uncommon within swedish conventional cancer care and little is known about cancer patients' own use of cam. the aim of this cross-sectional study was to explore swedish cancer patients´ patterns of cam use, their experiences and preferences. | 2019 | 30866916 |
population health inequalities across and within european metropolitan areas through the lens of the euro-healthy population health index. | the different geographical contexts seen in european metropolitan areas are reflected in the uneven distribution of health risk factors for the population. accumulating evidence on multiple health determinants point to the importance of individual, social, economic, physical and built environment features, which can be shaped by the local authorities. the complexity of measuring health, which at the same time underscores the level of intra-urban inequalities, calls for integrated and multidimens ... | 2019 | 30866549 |
erratum for euro surveill. 2019;24(8). | 2019 | 30862328 | |
standardisation and consensus guidelines for minimal residual disease assessment in philadelphia-positive acute lymphoblastic leukemia (ph + all) by real-time quantitative reverse transcriptase pcr of e1a2 bcr-abl1. | minimal residual disease (mrd) is a powerful prognostic factor in acute lymphoblastic leukemia (all) and is used for patient stratification and treatment decisions, but its precise role in philadelphia chromosome positive all is less clear. this uncertainty results largely from methodological differences relating to the use of real-time quantitative pcr (qrt-pcr) to measure bcr-abl1 transcript levels for mrd analysis. we here describe the first results by the euro-mrd consortium on standardizati ... | 2019 | 30858550 |
the cost effectiveness of helicobacter pylori population screening-economic evaluation alongside a randomised controlled trial with 13-year follow-up. | helicobacter pylori eradication improves dyspeptic symptoms in 8%-10%, prevents peptic ulcer and may reduce the risk of gastric cancer. availability of a high quality diagnostic test and an effective treatment makes population screening and eradication of helicobacter pylori an attractive option. | 2019 | 30854700 |
mesenchymal chondrosarcoma of maxilla in paediatric patient. | chondrosarcoma (cs) is a malignant tumour of long and flat bone characterised by the formation of cartilage. mesenchymal chondrosarcoma (mcs) is a rare subtype of cs that is more aggressive and may lead to erroneous diagnosis in a limited biopsy. the diagnosis is mainly based on the histopathological appearance of biphasic pattern of undifferentiated small round cells separated by islands of well-differentiated hyaline cartilage. we report a case of 13-year-old boy who initially presented with g ... | 2019 | 30852518 |
criteria and aldehyde emissions from a diesel euro v engine using diesel/biodiesel blends in brazil. | the brazilian legislation does not establish limits or methodology for the measurement of aldehydes in the exhaust of heavy diesel engines. no conclusive studies on aldehyde emissions by such engines have been found in the literature available. this work measured the aldehyde emissions from a p7 diesel cycle engine (euro v), which was tested on an engine test bench according to etc (european transient cycle) and esc (european stationary cycle) cycles using fuels with 5, 7 and 20% v/v of biodiese ... | 2019 | 30850980 |
low antimicrobial resistance rates of mycobacterium tuberculosis complex between 2000 and 2015 in gipuzkoa, northern spain. | although the incidence of tuberculosis (tb) has declined, tb drug resistance remains a major problem. the tb rate in gipuzkoa (northern spain) is higher than the european average. the objective of this study was to determine the antimicrobial susceptibility of 1855 mycobacterium tuberculosis complex isolates (94.5% of confirmed cases between 2000 and 2015). | 2019 | 30850232 |
diabetic and cardiovascular patients' willingness to pay for upcoming national health insurance scheme in côte d'ivoire. | côte d'ivoire's current health care financing system results from successive reforms undertaken with government funding and international support. the country is moving towards a national compulsory health insurance scheme. this context offered an opportunity to study additional features of health insurance's potential market in sub-sahara africa developing economy. this study examined patients' willingness to pay in order to get access to health care when it is needed. | 2019 | 30848393 |
cell therapy to improve regeneration of skeletal muscle injuries. | diseases that jeopardize the musculoskeletal system and cause chronic impairment are prevalent throughout the western world. in germany alone, ~1.8 million patients suffer from these diseases annually, and medical expenses have been reported to reach 34.2bn euros. although musculoskeletal disorders are seldom fatal, they compromise quality of life and diminish functional capacity. for example, musculoskeletal disorders incur an annual loss of over 0.8 million workforce years to the german econom ... | 2019 | 30843380 |
health resource use and costs of symptomatic knee and/or hip osteoarthritis. | data on the economic consequences of hip and knee osteoarthritis (oa) are scarce. we aimed to estimate the annual direct and indirect costs for patients followed for hip and/or knee oa in the knee and hip osteoarthritis long term assessment (khoala) cohort. | 2019 | 30922982 |
cost-effectiveness of the treatments for critical limb ischemia in the elderly population. | the treatment of critical limb ischemia (cli), with the intention to prevent limb loss, is often an intensive and expensive therapy. the aim of this study was to examine the cost-effectiveness of endovascular and conservative treatment of elderly cli patients unsuitable for surgery. | 2019 | 30922757 |
socioeconomic and ethnic differences in the relation between dietary costs and dietary quality: the helius study. | healthier dietary patterns are generally more costly than less healthy patterns, but dietary costs may be more important for dietary quality in lower educated and ethnic minority groups. the aim of this study was to investigate the association between dietary costs and dietary quality and interactions with ethnicity and socioeconomic position (sep). | 2019 | 30922320 |
economic evaluation of the hepatitis c elimination strategy in greece in the era of affordable direct-acting antivirals. | hepatitis c virus (hcv) is a leading cause of worldwide liver-related morbidity and mortality. the world health organization released an integrated strategy targeting hcv-elimination by 2030. this study aims to estimate the required interventions to achieve elimination using updated information for direct-acting antiviral (daa) treatment coverage, to compute the total costs (including indirect/societal costs) of the strategy and to identify whether the elimination strategy is cost-effective/cost ... | 2019 | 30918426 |
the evolution of health care utilisation and costs for inflammatory bowel disease over ten years. | inflammatory bowel disease [ibd] places an economic strain on health systems due to expensive pharmaceutical therapy, risk of hospitalisation and surgery, and long-term monitoring. the evolving treatment guidelines advocate rapid scale-up to biologic agents in order to improve health outcomes and quality of life. this study evaluated changes in health care utilisation and expenditures for ibd in switzerland over time. | 2019 | 30916775 |
ten years of external quality assessment (eqa) of neisseria gonorrhoeae antimicrobial susceptibility testing in europe elucidate high reliability of data. | confidence in any diagnostic and antimicrobial susceptibility testing data is provided by appropriate and regular quality assurance (qa) procedures. in europe, the european gonococcal antimicrobial susceptibility programme (euro-gasp) has been monitoring the antimicrobial susceptibility in neisseria gonorrhoeae since 2004. euro-gasp includes an external quality assessment (eqa) scheme as an essential component for a quality-assured laboratory-based surveillance programme. participation in the eq ... | 2019 | 30909883 |
spatial variability in air pollution exposure in relation to socioeconomic indicators in nine european metropolitan areas: a study on environmental inequality. | a limited number of studies have addressed environmental inequality, using various study designs and methodologies and often reaching contradictory results. following a standardized multi-city data collection process within the european project euro-healthy, we conducted an ecological study to investigate the spatial association between nitrogen dioxide (no2), as a surrogate for traffic related air pollution, and ten socioeconomic indicators at local administrative unit level in nine european me ... | 2019 | 30909127 |
climate co-benefits of alternate strategies for tourist transportation: the case of murree hills in pakistan. | this study explores the climate impacts of on-road tourist transportation with alternate mitigation strategies. to this end, greenhouse gas (ghg) emissions for 2016 and emissions under four "what-if" scenarios were estimated for a popular tourist site in pakistan, i.e., murree hills, using the international vehicle emissions model. alternate scenarios included occupancy optimization, bus transit system, and euro ii and euro iv implementation. the emissions were further decomposed using the log m ... | 2019 | 30903472 |
development of a road traffic emission inventory with high spatial-temporal resolution in the world's most densely populated region-macau. | with rapid economic growth, road transport is contributing substantial adverse effects on urban air quality, especially in densely populated cities with high growth rate of gdp per capita, such as macau. a high spatial-temporal resolution road traffic emission inventory is essential for assessment of environmental stresses imposed by local vehicle movements. to improve the accuracy and temporal-spatial resolution for emission inventory, through a bottom-up approach, link-based road traffic emiss ... | 2019 | 30903290 |
historical overview of regulatory framework development on pricing and reimbursement of medicines in bulgaria. | objectives: the current study aims to analyze, from a historical perspective, the regulatory framework of prices and reimbursement in bulgaria with emphasis on the introduction of economic evaluation.methods: the study explores all regulatory changes during the period 1995-2016 combining the macroeconomic and regulatory analysis on medicines pricing and reimbursement. a roadmap summarizing the current regulatory requirements for the medicinal product entrance on national market and access to pub ... | 2019 | 30900482 |
selection of a set of biomarkers and comparisons of biological age estimation models for korean men. | biological age (ba) represents the rate of the senescence with a set of biomarkers. the ba prediction models have not been compared to obtain an optimal ba prediction model with ba biomarkers for korean men. the study aims to obtain a set of ba biomarkers and compare three of the reported statistical approaches for an optimal ba prediction model. the korea national health and nutrition examination surveys data of 2009 to 2011 were used to select six ba biomarkers from 940 healthy subjects aged b ... | 2019 | 30899733 |
a comparative cost-effectiveness analysis of percutaneous transluminal angioplasty with optional stenting and femoropopliteal bypass surgery for medium-length tasc ii b and c femoropopliteal lesions. | to evaluate the total midterm costs and cost-effectiveness of percutaneous transluminal angioplasty with optional stenting (pta/s) as initial treatment compared with femoropopliteal bypass (fpb) surgery in patients with medium-length transatlantic inter-society consensus ii (tasc) b and c femoropopliteal lesions. | 2019 | 30898070 |