Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| antidepressant medication use and breast cancer risk: a case-control study. | animal and human studies have reported an association between antidepressant (ad) medication use and breast cancer risk. a population-based case-control study was designed specifically to examine this association among women in ontario, canada. | 2003 | 14681256 |
| [historical archives of italian nephrology. diabetic nephropathy and insulin discovery: two parallel histories]. | in 1936, kimmelstiel and wilson described the nodular glomerulosclerosis in patients with diabetes mellitus on insulin treatment. the nodular glomerulosclerosis is referred to as diabetic nephropathy. fifteen years earlier insulin was discovered. this discovery at the university of toronto (canada) in 1921-22 by banting, macleod, best and collip was one of the most dramatic events in the history of the treatment of the disease. the impact of insulin was so sensational because of the incredible e ... | 2003 | 14732916 |
| canada: national summit on "global health is a human right"! | held in ottawa on 21-22 may 2003, a national summit on "global health is a human right!" brought together 86 people representing over 60 canadian civil society groups interested in joint advocacy on realizing the human right to health in developing countries. the summit focused particularly on addressing the global crises of communicable diseases such as hiv/aids, tuberculosis, and malaria. | 2003 | 14746307 |
| impaired repression at a 5-hydroxytryptamine 1a receptor gene polymorphism associated with major depression and suicide. | inhibition of serotonergic raphe neurons is mediated by somatodendritic 5-ht1a autoreceptors, which may be increased in depressed patients. we report an association of the c(-1019)g 5-ht1a promoter polymorphism with major depression and suicide in separate cohorts. in depressed patients, the homozygous g(-1019) allele was enriched twofold versus controls (p = 0.0017 and 0.0006 for g/g genotype and g allele distribution, respectively), and in completed suicide cases the g(-1019) allele was enrich ... | 2003 | 14507979 |
| management of return-to-work programs for workers with musculoskeletal disorders: a qualitative study in three canadian provinces. | in this qualitative research project, researchers in three canadian provinces explored the perceptions of many different actors involved in return-to-work (rtw) programs for injured workers, studying their views on successful rtw strategies and barriers to/facilitators of the rtw process, then analyzing the underlying dynamics driving their different experiences. each research team recruited actors in a variety of different workplaces and key informants in the rtw system, and used a combination ... | 2003 | 14512241 |
| polyphenolic profiles in eight apple cultivars using high-performance liquid chromatography (hplc). | polyphenolic compounds of apple may play an important role in physiologic functions related to human health. different polyphenolics may have varied biological activities including antioxidant activity. the objective of this study was to investigate the profiles of polyphenolic compounds in different apple varieties and different parts of an apple. the total and individual polyphenolics differed significantly among the eight apple cultivars grown in ontario, and the peels had higher concentratio ... | 2003 | 14518966 |
| conservation of endangered species and the patterns and propensities of biodiversity. | it is commonly asserted in the ecological and economic literature that habitat loss is the main cause of loss of imperiled species. the evidence clearly shows that habitat loss is a common contributing factor, but there is little evidence that it is the most important factor. studies that have focused on the mechanisms of species loss have failed to produce models capable of predicting patterns of loss as a function of human activities. i propose that this is because ecologists have employed an ... | 2003 | 14558457 |
| maternal serum screening in ontario using the triple marker test. | to summarise the experience and evaluate the performance of the ontario maternal serum screening (mss) programme. | 2003 | 14561260 |
| how does fluoride concentration in the tooth affect apatite crystal size? | despite fluoride's (f) well-documented ability to prevent caries, the effects of f concentrations on enamel and dentin apatite crystals are unknown. the present study examined the hypothesis that tooth f concentration and tooth crystallite size correlate. one hundred human unerupted third molars were studied-53 from fortaleza-brazil (f water 0.7 ppm), 23 from toronto (1.0 ppm), and 24 from montreal (0.2 ppm). f concentration was analyzed by neutron activation analysis and apatite crystal size by ... | 2003 | 14578504 |
| beyond demographic change in human resources planning: an extended framework and application to nursing. | to introduce health care production functions into human resources planning and to apply the approach to analysing the need for registered nurses in ontario during a period of major reduction in inpatient capacity. | 2003 | 14596757 |
| growing older: the lived experience of older persons with serious mental illness. | the purpose of this qualitative paper is to describe, from the consumers' perspective, the complex factors involved as persons with serious mental illness grow older in the community. the results consisted of seven major themes subsumed under three categories. the first category, across the lifespan, included three themes: (a) older but wiser, (b) one day at a time, and (c) echoes from the past. the second category, factors impeding participation in the life of the community, also included three ... | 2003 | 15462578 |
| the baycrest sars experience: the human side. | toronto, in the province of ontario, canada was one of the cities severely impacted by severe acute respiratory syndrome (sars). sars required the health care system to respond quickly and efficiently. this paper describes the situation and response at a large public academic aged care centre. | 2003 | 15368814 |
| factors influencing childhood influenza immunization. | following the launch of a publicly funded influenza immunization program for all residents of ontario over the age of 6 months, we evaluated 203 parents of children who presented to our emergency department between january and march of the following year (2001). overall, 54 (27%) of the children had been vaccinated. parents of non-immunized children were more likely to believe that immunization resulted in a flu-like illness (42% v. 17%; p = 0.001), caused side effects that were more severe than ... | 2003 | 12515783 |
| regional distribution of antibodies to herpes simplex virus type 1 (hsv-1) and hsv-2 in men and women in ontario, canada. | this study estimated the regional and age- and gender-specific seroprevalences of herpes simplex virus type 1 (hsv-1) and hsv-2 in ontario, canada. stored serum specimens from subjects aged 15 to 44 years, including men (n = 979), women not under prenatal care (n = 638), and women under prenatal care (n = 701) submitted for routine viral serology were randomly selected according to regional population size from public health laboratories. hsv-1 and hsv-2 testing was done with the mrl enzyme immu ... | 2003 | 12517830 |
| delayed application of condoms is a risk factor for human immunodeficiency virus infection among homosexual and bisexual men. | the objective of this analysis was to identify risk factors for recent human immunodeficiency virus (hiv) infection among homosexual and bisexual men in ontario, canada, during 1998-2001. participants were recruited through the provincial hiv diagnostic laboratory and through physicians and community organizations. hiv test results were used to identify recent seroconverters (cases). a subsample of 183 men (62 cases and 121 controls) enrolled in the polaris hiv seroconversion study as of june 20 ... | 2003 | 12543620 |
| glucose intolerance in children with cystic fibrosis. | to evaluate the relations among glucose intolerance, genotype, and exocrine pancreatic status in patients with cystic fibrosis (cf). | 2003 | 12584532 |
| rural nonphysician providers' perspectives on palliative care services in northwestern ontario, canada. | most palliative care in rural remote areas is provided by nonphysicians. this paper reports a survey of interdisciplinary rural health service providers (not including physicians) to identify the strengths and weaknesses in palliative care service delivery in a rural and remote region in northwestern ontario, canada. questionnaires were sent to 156 nurses, homemakers, social workers, and pastoral care workers who care for terminally ill persons and their families, and 122 were completed and retu ... | 2003 | 12585775 |
| incidence, clearance and predictors of human papillomavirus infection in women. | persistent infection with carcinogenic human papillomavirus (hpv) is linked to high-grade lesions and cervical cancer. to better understand the natural history of hpv, we sought to determine the rates of incident and cleared carcinogenic hpv infection, by age, among women aged 15-49 years and to explore risk factors for incident infection. | 2003 | 12591782 |
| oseltamivir for treatment of influenza in healthy adults: pooled trial evidence and cost-effectiveness model for canada. | influenza is a common viral respiratory infection that is associated with significant morbidity. oseltamivir (tamiflu) is a neuraminidase inhibitor-a new class of antiviral treatment for influenza where efficacy and safety has been established but cost-effectiveness is unknown. | 2003 | 12641862 |
| the olivieri report--a compelling study of the growing tensions in clinical research. | 2003 | 12645235 | |
| wombs for rent: an examination of prohibitory and regulatory approaches to governing preconception arrangements. | on october 9, 2002, bill c-13 had its first reading in the canadian house of commons. bill c-13 was in the same form as bill c-56 of the first session of the thirty-seventh parliament, which had its first reading on may 9, 2002. bill c-13, an act respecting assisted human reproduction, prohibits the practice of commercial surrogacy or preconception agreements in canada, under threat of criminal sanction. in the first half of the article, the author discusses the deficiencies of the bill's prohib ... | 2003 | 12674583 |
| impact on blood pb levels of maternal and early infant feeding practices of first nation cree in the mushkegowuk territory of northern ontario, canada. | exposure to pb in-utero and in infancy has been associated with cognitive risk, even at low blood pb levels of 0.48-0.96 micromol l(-1). based on the hypothesis that wild game consumed by first nation women of mushkegowuk territory contains pb that might be transferred through blood or breast-milk to the fetus or infant, the study's objectives were to describe: (1) pb in maternal and cord blood at birth and infant blood at 4 months, and (2) dietary influence on pb status. cord and maternal pb we ... | 2003 | 12729262 |
| emancipatory responses to oppression: the template of land-use planning and the old order amish of ontario. | in this paper i discuss the clash of values between the old order amish community of ontario and the dominant social paradigm in agriculture. land-use and agricultural regulations, designed for an industrial style of agriculture, are experienced as a threat to the survival of the old order amish agricultural social economy and community. the paper describes how i have worked with the old order amish to respond to these challenges and to create public policies that will allow them to maintain the ... | 2003 | 12741697 |
| seroprevalence of toxoplasma gondii infection among veterinary staff in ontario, canada (2002): implications for teratogenic risk. | toxoplasma gondii infection is embryotoxic in humans. it is mainly transmitted through raw/undercooked meat and ingestion of oocysts in cat feces. there remains controversy about the actual risk of cats transmitting the disease to humans. our primary objective was to determine the seroprevalence of t. gondii antibody among veterinary staff, to ascertain whether they have an increased risk through occupational exposure. our secondary objective was to examine their practices regarding cats, toxopl ... | 2003 | 12769831 |
| [another case of west nile fever in the netherlands: a man with encephalitis following a trip to canada]. | shortly after his return to the netherlands from a trip to ontario, a part of canada where infection with west-nile virus has been reported, a 69-year-old man became increasingly confused and generally unwell, accompanied by fever. the clinical picture was compatible with viral encephalitis and this was supported by eeg findings and the results of the cerebrospinal-fluid examination. mri of the brain did not contribute to the diagnosis. the patient was treated with aciclovir because herpes simpl ... | 2003 | 12784533 |
| investigating adverse outcomes in obstetrics. | investigation of adverse outcomes in health care requires a systematic and systemically oriented approach. this is true in obstetrics where, in western countries such as canada, adverse outcomes in the form of maternal mortality are rare. a model for such investigation is presented, based on answers to 3 questions: what? how? and why? these questions correspond to donabedian's 3 components of quality assurance: outcome, process, and structure, respectively. aspects of reason's model of accidents ... | 2003 | 12806452 |
| accuracy of trisomy 18 screening using the second-trimester triple test. | to assess the accuracy of the calculated risk for trisomy 18 assigned to individual women screened with the second-trimester triple test. | 2003 | 12813756 |
| isolation of candida dubliniensis in an aboriginal community in ontario, canada. | this study reports the first isolation of candida dubliniensis from north american indians. of 39 healthy human hosts sampled, two had c. dubliniensis. genotypic analysis identified polymorphisms in these strains and differences from two reference strains. our results suggest that yeast populations from indigenous communities in north america may be unique. | 2003 | 12843110 |
| the role of air pollution in the relationship between a heat stress index and human mortality in toronto. | in this study we considered confounding from air pollutants and chronological variables in the relation between humidex, a summer temperature and humidity index, and nonaccidental mortality, from 1980-1996 in toronto, canada. changes in the risk of death by age group, gender, and combined cardiac-respiratory cause of death were estimated for both 1 degree c and 50-95th percentile increases in humidex using a generalized additive linear model. with air pollution terms in the models, relative risk ... | 2003 | 12865043 |
| quadricuspid semilunar valves: report of two cases. | quadricuspid semilunar valves are uncommon congenital anomalies sometimes associated with severe valvular dysfunction. two cases of isolated quadricuspid semilunar valve were identified. the first, a heavily calcified quadricuspid aortic valve with four equal-sized cusps, was identified in a 56-year-old man at the time of valve replacement surgery for severe aortic stenosis and regurgitation. the second valve was a quadricuspid pulmonary valve with three equal-sized cusps and one smaller cusp, i ... | 2003 | 12876615 |
| effect of breastmilk consumption on neurodevelopmental outcomes at 6 and 12 months of age in vlbw infants. | to determine the influence of breastmilk consumption, as a dose response, in very low-birth-weight (vlbw) infants (< 1,500 g) on neurodevelopmental outcomes at 6 and 12 months corrected age, and to determine the influence of selected sociodemographic and infant variables on neurodevelopmental outcomes. | 2003 | 12881949 |
| prior opiate injection and incarceration history predict injection drug use among inmates. | to describe injection drug use among inmates, and to identify correlates of drug injection while incarcerated. | 2003 | 12930213 |
| seeing double, thinking twice: the toronto drag kings and (re-) articulations of masculinity. | through a close reading of the performances of masculinity by the toronto drag kings, this chapter argues that drag king shows parody the hyper-masculine star at his most contradictory and dialogic. given that drag king performances parody both the contradictions of masculinity on stage, and the productive technologies of the star, king performances are essentially both meta-theatrical (performances about performing where lights, music, body language, dance all make the man) and meta-performativ ... | 2002 | 12769283 |
| where to from here? | although this conceptual framework is easy to understand, the data requirements for the mathematical model that underpins the framework are complex and must be defined carefully. in our framework, simulations of the health system are used to provide needs-based estimates that are aimed at optimizing outcomes. this type of model builds on research conducted at the macro, meso, and micro levels in order to reflect the complexity of relationships in the health human resource process. the papers in ... | 2002 | 11998195 |
| realizing potential: improving interdisciplinary professional/paraprofessional health care teams in canada's northern aboriginal communities through education. | to address a shortage of health professional human resources and to overcome cultural barriers, the interdisciplinary health care teams practicing in most northern canadian aboriginal communities include a number of paraprofessionals recruited locally. this model has great potential to fill service gaps in many rural contexts; there are challenges, however. drawing from an extensive program of research in indigenous communities in the northwestern part of the province of ontario, we identify fac ... | 2002 | 12028894 |
| the effect of a hepatitis serology testing algorithm on laboratory utilization. | laboratory testing algorithms use patient and laboratory data to identify the optimal testing strategy for patients. studies have shown that these algorithms can decrease test utilization. since over-utilization of hepatitis serological tests was suspected, a hepatitis serology testing algorithm was initiated in ontario, canada. this study determined the effects of this algorithm on utilization. | 2002 | 12164979 |
| more money would put an end to emergency room crunches. | 2002 | 12171753 | |
| a physician workforce planning model applied to canadian anesthesiology: assessment of needs. | a human resource planning model for anesthesiology is described. | 2002 | 12193482 |
| patient-focused care on a complex continuing care dialysis unit: rose's story. | using the standards of patient-focused care and the values of parse's human becoming school of thought, nurses at sunnybrook and women's college health sciences centre in toronto, ontario are exploring new ways to be with patients needing continuous ambulatory peritoneal dialysis on complex continuing care units. for patients such as rose, health and quality of life are being enhanced through the practice of these methodologies. "i feel cared for." how can health care professionals nurture perso ... | 2002 | 12387129 |
| acceptability and impact of pet visitation on a pediatric cardiology inpatient unit. | we evaluated the effectiveness of a pet visitation program in helping children and their families adjust to hospitalization on a pediatric cardiology ward. thirty-one pet visits were observed and followed by interviews with patients and parents. analysis of data suggested that pet visits relieved stress, normalized the hospital milieu, and improved patient and parent morale. the benefit received by the subjects correlated with the amount of physical contact and rapport developed with the visitin ... | 2002 | 12395303 |
| building capacity in nursing: creating a leadership institute. | the authors describe the development of the dorothy m. wylie nursing leadership institute, an innovative partnership of the nursing effectiveness, outcomes and utilization research unit at the university of toronto site and nurse consultants with expertise in organizational and human resource development. the context for the initiative, needs and rationale, supporting literature and the coalition-building and planning activities are outlined. the program and its conceptual underpinnings, creatio ... | 2002 | 12395973 |
| the importance of being marginal: norma ford walker and a canadian school of medical genetics. | this study reviews the development of a medical genetics research tradition in toronto, canada. this research tradition, what i call the "ford walker school," was forged in the 1930s in an iconoclastic mold. it was female-dominated in an era when leading-edge science was definitely not "women's work." it emerged in a leading research university, but in a country that lagged in the sciences. these social relations of gender and nation symbolized and sustained a marginality that was reinforced by ... | 2002 | 12400056 |
| utility of zanamivir for chemoprophylaxis of concomitant influenza a and b in a complex continuing care population. | to describe compliance with and the safety and prophylactic efficacy of zanamivir among patients at risk of developing influenza-related complications after exposure to both influenza a and b viruses. | 2002 | 12400891 |
| nosocomial influenza at a canadian pediatric hospital from 1995 to 1999: opportunities for prevention. | nineteen cases of nosocomial influenza occurred at a pediatric hospital during a 5-year period. only one of the nine children with chronic health conditions had been immunized. length of stay was prolonged for seven children, with three intensive care unit admissions. we have now implemented strategies to decrease nosocomial influenza infection. | 2002 | 12400897 |
| prevalence of infection with carcinogenic human papillomavirus among older women. | 2002 | 12406945 | |
| it ain't necessarily so: most women do not strongly prefer female obstetrician-gynaecologists. | to examine whether canadian women seeking care from obstetrician-gynaecologists prefer to see female or male physicians or have no strong preference in this regard. | 2002 | 12417903 |
| insulin: discovery and controversy. | during the first two decades of the 20th century, several investigators prepared extracts of pancreas that were often successful in lowering blood sugar and reducing glycosuria in test animals. however, they were unable to remove impurities, and toxic reactions prevented its use in humans with diabetes. in the spring of 1921, frederick g. banting, a young ontario orthopedic surgeon, was given laboratory space by j.j.r. macleod, the head of physiology at the university of toronto, to investigate ... | 2002 | 12446492 |
| lcd versus crt displays: a comparison of visual search performance for colored symbols. | visual search performance for tactical symbols was examined with liquid-crystal (lcd) and cathode-ray tube (crt) displays. twenty-four adult participants (19 men, 5 women; mean age 41 years) searched for navy tactical display symbols on a map background. lcd and crt displays of similar size and resolution (52 cm diagonal, 1280 x 1024 pixels) were used. viewing angle (0 degrees vs. 60 degrees of azimuth), set size, target color (blue, red, or white), target presence, and search type (feature vs. ... | 2002 | 12452269 |
| air pollution induces heritable dna mutations. | hundreds of thousands of people worldwide live or work in close proximity to steel mills. integrated steel production generates chemical pollution containing compounds that can induce genetic damage (1, 2). previous investigations of herring gulls in the great lakes demonstrated elevated dna mutation rates near steel mills (3, 4) but could not determine the importance of airborne or aquatic routes of contaminant exposure, or eliminate possible confounding factors such as nutritional status and d ... | 2002 | 12473746 |
| inter- and intra-observer reliability of calculating cumulative lumbar spine loads. | the aim of this study was to quantify the precision of manual video digitization of three typical industrial tasks, as evaluated by the comparison of four cumulative kinetic parameters at the l4/l5 intervertebral joint: compression, joint shear, reaction shear and moment. ten observers were recruited (five male and five female), with an undergraduate background in human anatomy. on each of three test days, each observer digitized five repeats of each of three typical industrial lifting tasks of ... | 2002 | 12487691 |
| desired elements of hiv testing services: test recipient perspectives. | thematic analysis of transcripts from interviews with a purposive sample of 39 voluntary human immunodeficiency virus (hiv) test recipients in ontario (selected on the basis of hiv serostatus, risk behaviors, region of residence, gender, and testing format) was used to identify elements of hiv testing services of concern to test recipients. colleague review was used to ensure dependability of findings, and emergent themes were compared with the existing literature on patient satisfaction. data a ... | 2002 | 12513902 |
| human surveillance for west nile virus infection in ontario in 2000. | the first reports of west nile virus (wnv) infection in the united states in 1999 prompted ontario to establish a surveillance protocol to monitor for the possible spread of the virus into the province. surveillance components included evaluation of dead birds, sentinel chickens, mosquito pools and human disease. we report the results of human surveillance in 2000. | 2002 | 11800244 |
| regression models for allele sharing: analysis of accumulating data in affected sib pair studies. | advances in human genome mapping have led to the identification of large numbers of genetic markers that allow systematic searches for multiple disease susceptibility genes for complex traits. a common design involves the recruitment of families with at least two children affected with the disease of interest. the objective is to find chromosomal regions that harbour susceptibility genes for the disease. the affected children, their parents if available, and sometimes other, unaffected, siblings ... | 2002 | 11813229 |
| questions of interest. | 2002 | 11873912 | |
| postexposure treatment and animal rabies, ontario, 1958-2000. | this paper investigates the relationship between animal rabies and postexposure treatment (pet) in ontario by examining the introduction of human diploid cell vaccine (hdcv) in 1980 and the initiation of an oral rabies vaccination program for wildlife in 1989. introducing hdcv led to an immediate doubling of treatments. both animal rabies and human treatments declined rapidly after the vaccination program was introduced, but human treatments have leveled off at approximately 1,000 per year. | 2002 | 11897079 |
| hnf-1alpha g319s, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an oji-cree community. | the prevalence of type 2 diabetes mellitus in the oji-cree of northwestern ontario is the third highest in the world. a private mutation, g319s, in hnf1a, which encodes hepatic nuclear factor-1alpha (hnf-1alpha), was associated with oji-cree type 2 diabetes and was found in approximately 40% of affected subjects. the g319s mutation reduced the in vitro ability of hnf-1alpha to activate transcription by approximately 50%, with no effect on dna binding or protein stability. there was no evidence o ... | 2002 | 11904371 |
| supply and demand for cardiac nurses in ontario: perceptions of cnos. | this article presents the results of a nursing survey of cardiac care hospitals undertaken by a cardiac care network of ontario consensus panel on cardiovascular human resources. the focus of the panel was to identify areas of current or pending shortages in human resources and make recommendations to the ministry of health and long-term care about human resource management in adult cardiac care in ontario. the article presents the number and mix of full-time, part-time and casual nursing staff, ... | 2002 | 11908543 |
| conflicting interests in toronto: anatomy of a controversy at the interface of academia and industry. | in december 2000, the university of toronto breached a contract it held with me, initiating a sequence of events that has led to a public letter to the university from a large number of senior figures in the psychopharmacology community, protesting against the infringement of academic freedom involved, and a first-ever legal action seeking redress for violation of academic freedom. this case has been intertwined from the start with a longer running debate about the possibility that the ssri grou ... | 2002 | 11919383 |
| associations between indicators of livestock farming intensity and incidence of human shiga toxin-producing escherichia coli infection. | the impact of livestock farming on the incidence of human shiga toxin-producing escherichia coli (stec) infection was assessed by using several livestock density indicators (ldi) that were generated in a systematic approach. a total of 80 ldi were considered suitable proxy measures for livestock density. multivariate poisson regression identified several ldi as having a significant spatial association with the incidence of human stec infection. the strongest associations with human stec infectio ... | 2002 | 11927021 |
| paramedics face dismissal for refusing flu shots. | 2002 | 11944775 | |
| perception of genuine and masking smiles in children and adults: sensitivity to traces of anger. | the authors examined children's and adults' sensitivity to traces of anger in masking smiles by presenting participants with short video excerpts of smiles that differed by the intensity of an anger component. fifty-two children, aged 6 to 12 years, and 26 adults were asked to judge whether a stimulus person was really happy or pretending to be happy. six- and 7-year-old children were found to be sensitive to traces of anger, but less so than older children and adults. researchers found evidence ... | 2002 | 11952265 |
| use of oseltamivir during influenza outbreaks in ontario nursing homes, 1999-2000. | to describe the experience of ontario long-term care facilities that used oseltamivir during influenza outbreaks in 1999/2000. | 2002 | 11982659 |
| a survey of physicians knowledge regarding awareness of maternal alcohol use and the diagnosis of fas. | alcohol is the most widely used drug in the world that is a human teratogen whose use among women of childbearing age has been steadily increasing. it is also probable that fetal alcohol syndrome is under diagnosed by physicians. the objectives of this study were twofold: 1) to evaluate the experience, knowledge and confidence of family physicians with respect to the diagnosis of fas and 2) to evaluate physicians awareness of maternal drinking patterns. | 2002 | 11860607 |
| construction and validation of a fatigue impact scale for daily administration (d-fis). | the fatigue impact scale (fis) was developed previously as a symptom-specific profile measure of health-related quality of life (hrqol) for use in medical conditions in which fatigue is a prominent chronic symptom. thus, it was not developed to be a responsive measure of daily changes in fatigue. this study describes the development and initial validation of an adaptation of the fis for daily use. items for the daily fatigue impact scale (d-fis) were selected from the pool of original fis items ... | 2002 | 12074263 |
| trends of medication errors in hospitalized children. | medication errors are a major cause of morbidity and mortality among hospitalized children. due to the small volumes of stock solution involved, even a large error may look as an unsuspiciously small dose. strategies were implemented to reduce medication errors in a large tertiary pediatric hospital in toronto. starting in 1993, several initiatives were taken, including a new hospital computer system for medication ordering, a review process to remove hazardous drugs from wards where they are no ... | 2002 | 12092737 |
| influence of temperature on cryptosporidium parvum oocyst infectivity in river water samples as detected by tissue culture assay. | cryptosporidium parvum oocysts were stored in 1-ml aliquots of filtered river water at -20, 4, 10, and 21-23 c in the dark. oocysts were also added to filter-sterilized river water samples and stored at 21-23 c. the infectivity of oocysts stored under different conditions was assayed at weekly intervals through infection of human adenocarcinoma ileocecal (hct-8) cell monolayers. wells containing between 10 and 100 foci of infection were enumerated by immunofluorescent microscopy, and the number ... | 2002 | 12099446 |
| the experiences of professional nurses who have migrated to canada: cosmopolitan citizenship or democratic racism? | this interpretive research analyses the discourse of nurses who migrated to canada and experienced racism. they also experienced reprisals when they formally complained about racism in a context of denial of the problem of racism by colleagues and employers. the present work focuses on two issues arising from the data: the problem of how to make racism visible among those who have a vested interest in denying its existence and the emotional cool of those filing grievances or complaints in contra ... | 2002 | 12100877 |
| ontario appellate court denies hiv-positive man's constitutional claim to medical marijuana. | in january 2002, the ontario court of appeal denied a claim by a toronto man living with hiv/aids that canada's laws prohibiting marijuana possession and cultivation infringe his constitutional rights to liberty and security of the person. | 2002 | 14979265 |
| court orders publication ban in trial for identity of hiv-positive witness. | in september 2001, an ontario trial judge in a criminal assault case ordered a ban on publishing the identities of both the hiv-positive complainant and the man accused of assaulting the complainant, or any evidence from the legal proceedings that would tend to identify them. | 2002 | 14979269 |
| ontario commission criticizes insurance industry record on human rights. | 2002 | 14765494 | |
| ontario court recognizes constitutional equality rights of people "in receipt of social assistance". | on 13 may 2002, the ontario court of appeal released its unanimous decision in the falkiner case, which declared the definition of "spouse" in ontario's social assistance legislation to be unconstitutional because it discriminates on the basis of sex, marital status, and receipt of social assistance. the case is significant for people living with hiv/aids, given that a high proportion live on social assistance and thus face discrimination. | 2002 | 14765506 |
| gastrointestinal absorption of uranium in humans. | the gastrointestinal absorption factor (f1) for uranium in humans has been determined from a study of 50 volunteers, ingesting uranium at natural levels in drinking water and food. the purpose of the study was to find an appropriate f1 value for humans to use in deriving exposure guidelines for uranium. the participants ranged in age from 13 to 87 years. they were selected from two communities: new ross, nova scotia with elevated uranium in drinking water, and ottawa, ontario with very low level ... | 2002 | 12075682 |
| northern initiative for social action: an occupation-based mental health program. | northern initiative for social action (nisa) is a consumer-run, occupation-based, nonprofit organization located in northeastern ontario, canada. the nisa organization has grown in response to research revealing few opportunities for participation in personally meaningful and socially valued occupation for persons with mental illness living in the community of study. this article describes a mixed-design research study conducted by the parnorth research unit of nisa and an occupational therapist ... | 2001 | 14601808 |
| minimal risk and its implications. proceedings of the ncehr national workshop on minimal risk, march 31-april 1, 2000 held in ottawa, ontario, canada. | 2001 | 15540386 | |
| the gay cousin: learning to accept gay rights. | in 1996-97 the author interviewed 73 civic leaders in hamilton, ontario, canada, on their attitudes toward gay rights. twelve respondents opposed gay rights, 40 were moderately favorable to gay rights, and 21 were strongly favorable. almost all favored basic equality rights (education, housing, employment), and only 10 said they had difficulty with gay sexuality. twenty-seven volunteered a concern with gay "flaunting," but this did not mean that they necessarily opposed gay rights. respondents h ... | 2001 | 11991563 |
| motion to strike claim dismissed in hiv defamation suit. | on 23 april 2001, the ontario superior court of justice issued the first canadian ruling on the issue of whether words inputing that a person is hiv-positive or has aids can be the basis of a defamation action per se, in the case of serdar v metroland printing, publishing and distributing ltd. | 2001 | 11837012 |
| court dismisses constitutional challenge to ban on assisted suicide. | on 6 february 2001, the ontario superior court of justice dismissed a constitutional challenge by jim wakeford, a toronto man with hiv/aids and an advocate for access to medical marijuana, to the sections of the criminal code that outlaw assisted suicide in canada. | 2001 | 11837023 |
| new developments at the university of ottawa community legal clinic. | this is another in our series of articles about canadian legal clinics that provide specialized services to people with hiv/aids. vanessa gruben describes new trends in legal issues observed by the university of ottawa community legal clinic since the last article by the clinic in 1999, as well as other programs and projects undertaken by the clinic over the last year. | 2001 | 11837024 |
| the ontario mother and infant survey: breastfeeding outcomes. | a cross-sectional survey of postpartum women following discharge from five hospitals in ontario, canada, examined breatfeeding patterns and risk factors for early discontinuation. consenting mothers completed self-administered questionnaires prior to discharge (n = 1250) and telephone interviews at 4 weeks postdischarge (n = 875). breastfeeding initiation rates for women completing the interview varied from 82% to 96% across the sites. continuation rates rapidly declined, with 13% to 24% of wome ... | 2001 | 11847986 |
| diphyllobothriasis: update on human cases, foci, patterns and sources of human infections and future considerations. | diphylobothriasis is a well documented disease of humans. on a world scale new infections are reported regularly, especially from russia and parts of japan. globally, new species have been discovered and the etiology of the disease may be changing. human infections appear to be in decline but it is not clear if the sources of infection are also in decline or if public health awareness has improved. in north america there has been a decline in human cases while in south america an increase in rep ... | 2001 | 12041607 |
| continuing education for staff in long-term care facilities: corporate philosophies and approaches. | the purpose of this study was to determine corporate philosophies of continuing education and approaches to meeting the learning needs of staff who strive to provide for the increasingly challenging care requirements of seniors who reside in long-term care facilities. in-depth interviews lasting approximately 1 hour were conducted with key informants at the administrative level from nine long-term care facilities. content analysis revealed a commitment to continuing education for staff. while re ... | 2001 | 11868744 |
| identifying and prioritizing gaming workers' health and safety concerns using mapping for data collection. | this research was prompted by the clinical presentation of workers from a variety of gaming occupations with injuries and illnesses and multiple health and safety concerns. | 2001 | 11148014 |
| mass influenza vaccination in ontario: a sensible move. | 2001 | 11202665 | |
| mass influenza vaccination in ontario: is it worthwhile? | 2001 | 11202666 | |
| surveillance programs for early stage non-seminomatous testicular cancer: a practice guideline. | to identify an appropriate surveillance program for men with clinical stage i non-seminomatous germ cell tumors of the testis (nsgct). | 2001 | 11268306 |
| elimination of rabies from red foxes in eastern ontario. | the province of ontario (canada) reported more laboratory confirmed rabid animals than any other state or province in canada or the usa from 1958-91, with the exception of 1960-62. more than 95% of those cases occurred in the southern 10% of ontario (approximately 100,000 km2), the region with the highest human population density and greatest agricultural activity. rabies posed an expensive threat to human health and significant costs to the agricultural economy. the rabies variant originated in ... | 2001 | 11272485 |
| genes and environment in type 2 diabetes and atherosclerosis in aboriginal canadians. | the incidence of coronary heart disease (chd) among aboriginal people in northern ontario has tripled over the past 20 years. this is inextricably linked to the remarkably high prevalence of type 2 diabetes in these native communities. approximately 40% of the oji-cree of northern ontario have typical obesity-related type 2 diabetes, which represents a drastic increase from virtually unreportable levels 50 years ago. the oji-cree have a private mutation in the hnf1a gene, namely g319s, which is ... | 2001 | 11286643 |
| conflict resolution at the university of ottawa faculty of medicine: the pelican and the sign of the triangle. | in 1997 the university of ottawa medical school adopted a conflict-resolution policy for informally dealing with complaints of abuse, harassment and intimidation, sexual harassment, and scientific misconduct or misappropriation of intellectual property. in collaboration with the university's faculty of law, general conflict-resolution workshops were given for faculty and administration and mediation training was provided to medical faculty designated "complaint officers" under the policy. in thi ... | 2001 | 11299145 |
| waiting lists for radiation therapy: a case study. | why waiting lists arise and how to address them remains unclear, and an improved understanding of these waiting list "dynamics" could lead to better management. the purpose of this study is to understand how the current shortage in radiation therapy in ontario developed; the implications of prolonged waits; who is held accountable for managing such delays; and short, intermediate, and long-term solutions. | 2001 | 11319944 |
| respiratory virus surveillance. fluwatch project, 2000-2001. end of season update. | the 2000-2001 season was a relatively mild season worldwide. in canada, lower than usual activity was reported for all national indicators of influenza activity, including the rate of influenza-like illness (ili), the percentage of laboratory-confirmed cases of influenza and provincial/territorial influenza activity levels. however, there were a number of interesting characteristics of this year's influenza season. in contrast to the predominance of influenza a, and in particular the a/sydney/5/ ... | 2001 | 11416943 |
| ebv-associated perianal hodgkin's disease in an hiv-positive individual. | hodgkin's disease (hd) has a higher incidence in hiv-positive individuals. it tends to occur at extranodal sites, frequently exhibits an unfavorable histological type with large numbers of neoplastic cells, and almost invariably harbors epstein-barr virus (ebv). we describe a case of a 33-year-old hiv-positive man who presented with anal pain from a 4-cm mass in the anorectal canal. he had no b symptoms or peripheral lymphadenopathy. a chest x-ray was within normal limits. a biopsy showed an ulc ... | 2001 | 11426491 |
| fingerprinting pcb patterns among mohawk women. | this study examined the association of contaminated fish consumption and polychlorinated biphenyl (pcb) body burden by comparing the similarity of the congener pattern in yellow perch, caught near the point source of industrial pollution, and in other local fish to the pattern found in the breast milk of mohawk women from akwesasne, a native american community located along the st. lawrence river in new york, ontario, and quebec. the similarity is defined by the weighted euclidean distance betwe ... | 2001 | 11477516 |
| sense of place, organizational context and the strategic management of publicly funded hospitals. | an era of managerialism in health care delivery systems is now well ensconced throughout the nations of the oecd. this development has occurred, in large part, as a response to funding pressures in institutionally based health care delivery imposed by principal third party insurers. in the case of publicly funded hospitals, the more traditional concerns for stewardship and appeasement of professional groups is being replaced by a greater emphasis on cost consciousness and corporate-style leaders ... | 2001 | 11551664 |
| an exploratory analysis of the effect of pesticide exposure on the risk of spontaneous abortion in an ontario farm population. | the toxicity of pesticides on human reproduction is largely unknown--particularly how mixtures of pesticide products might affect fetal toxicity. the ontario farm family health study collected data by questionnaire on the identity and timing of pesticide use on the farm, lifestyle factors, and a complete reproductive history from the farm operator and eligible couples living on the farm. a total of 2,110 women provided information on 3,936 pregnancies, including 395 spontaneous abortions. to exp ... | 2001 | 11564623 |
| a g339r mutation in the ctns gene is a common cause of nephropathic cystinosis in the south western ontario amish mennonite population. | 2001 | 11565547 | |
| an outbreak of serratia marcescens associated with the anesthetic agent propofol. | in october 1999, 7 patients with postoperative infections caused by serratia marcescens were identified at a community hospital in ontario, canada. we describe the investigation of this outbreak. | 2001 | 11584257 |
| emergence of salmonella typhimurium definitive type 104 (dt104) as an important cause of salmonellosis in horses in ontario. | salmonella typhimurium definitive type 104 (dt104) has emerged as a common cause of salmonellosis in humans and cattle, yet previous reports involving horses are sparse. this study reports the emergence of dt104 as an important pathogen in horses in ontario. the first clinical case of dt104 infection at the ontario veterinary college was identified in 1997. seventeen cases of dt104-associated salmonellosis were identified between 1997 and 2000. in 2000, 12 of 13 cases of salmonellosis were due t ... | 2001 | 11665427 |
| prevalence of hepatitis e virus antibodies in canadian swine herds and identification of a novel variant of swine hepatitis e virus. | swine hepatitis e virus is a newly identified potentially zoonotic virus from pigs of particular concern for possible direct transmission to a human xenotransplant recipient by organ transplantation. in the present study, prevalence of serum antibodies to hepatitis e virus was examined in canadian swine herds. a total of 998 serum samples collected from 6-month-old healthy slaughter hogs were examined by enzyme immunoassay and western blot analysis for antibodies to the recombinant open reading ... | 2001 | 11687465 |
| cancer coverage in newspapers serving large and small communities in ontario. | local newspapers are an important source of health news, especially in small communities. we describe the amount and type of cancer information in ontario daily newspapers dichotomized by circulation size (> 400,000 or < 40,000) and community size (> 250,000 or < 25,000 people) for 1991. all cancer articles (n = 1027) in five newspapers with large circulations, serving large communities, and five newspapers with small circulations, serving small communities, were read and evaluated for focus and ... | 2001 | 11702493 |
| identification of human multidrug resistance protein 1 (mrp1) mutations and characterization of a g671v substitution. | the multidrug resistance protein 1 (mrp1) belonging to the atp-binding cassette (abc) superfamily of transport proteins can confer resistance to multiple natural product drugs and methotrexate in human tumor cells. in addition, mrp1 is expressed in normal tissues acting as an efflux pump for glutathione, glucuronate, and sulfate conjugates and may thus influence the pharmacokinetic properties of many drugs. using polymerase chain reaction-single-strand conformation polymorphism analysis, we scre ... | 2001 | 11721885 |