Publications

bacteriophage lambda fii gene protein: role in head assembly.		1974	4616093
repair mechanisms involved in the recovery of phage lambda from ultraviolet damage.		1973	4618990
properties of a mutant of escherichia coli defective in bacteriophage lambda head formation (groe). i. initial characterization.		1973	4578098
a new effect of the rex gene of phage lambda: premature lysis after infection by phage t1.		1973	4583305
prophage lambda at unusual chromosomal locations. ii. mutations induced by bacteriophage lambda in escherichia coli k12.		1973	4587404
isolation of the bacteriophage lambda receptor from escherichia coli.	a factor which inactivates the phage lambda can be extracted from escherichia coli. this factor is a protein and is located in the outer membrane of the bacterial envelope. it is found in extracts of strains which are sensitive to phage lambda, but not in extracts of strains specifically resistant to this phage. we conclude that this factor is the lambda receptor, responsible for the specific adsorption of the phage lambda to e. coli cells. a partial purification of the lambda receptor is descri ...	1973	4201774
genetic analysis of bacteriophage lambda strains which transduce the genes for leucine biosynthesis.		1973	4591366
control of gene expression in bacteriophage lambda.		1973	4593306
synthesis of bacteriophage lambda proteins in vitro.		1972	4343946
lambda phage transcription in human fibroblasts.		1972	4551993
on some genetic aspects of phage lambda resistance in e. coli k12.	most mutations rendering e. coli k12 resistant to phage lambda, map in two genetic regions mala and malb.-the malb region contains a gene lamb specifically involved in the lambda receptor synthesis. twenty-one independent lamb mutations studied by complementation belonged to a single cistron. this makes it very likely that lamb is monocistronic. among the lamb mutants some are still sensitive to a host range mutant of phage lambda. mutations mapping in a proximal gene essential for maltose metab ...	1972	4558324
interaction of the recombination pathways of bacteriophage lambda and host escherichia coli: effects on lambda recombination.		1972	4563260
methylation pattern of lambda deoxyribonucleic acid.	deoxyribonucleic acid (dna) extracted from phage lambda grown on escherichia coli k-12 strain w4032 had 113 +/- 10 5-methylcytosine residues and 215 +/- 20 6-methyl adenine residues per genome, as determined by three independent methods. these methylated nucleotides were distributed equally among the two strands of lambda dna. shearing of double-stranded dna to half-length fragments revealed a slight deficiency of 5-methyl cytosine in the 55% guanine plus cytosine half. shearing the dna to fragm ...	1972	4564587
purification and base composition analysis of phage lambda early promoters.	rna-polymerase of escherichia coli was allowed to bind to dna of phage lambda in the absence of precursors. the resulting complex was excised by nuclease digestion and the protected dna was recovered by phenol-extraction and ethanol precipitation. acrylamide gel electrophoresis of protected dna fragments reveals the existence of two distinct oligonucleotide peaks corresponding, respectively, to 45-52 and 7-10 nucleotide residues along with species of intermediate sizes. peak i molecules have two ...	1971	4332016
control of late messenger rna synthesis during lambda phage development.		1971	4926028
role of exonuclease and beta protein of phage lambda in genetic recombination. v. recombination of lambda dna in vitro.	the sequential action of lambda exonuclease and polynucleotide ligase upon redundant joint molecules is sufficient to produce intact polynucleotide chains and heat-stable, biologically active molecules of lambda dna, whereas the action of ligase alone is insufficient. these results (a) confirm the previously described mechanism of single-strand assimilation, including a subsidiary mechanism by which the further action of lambda exonuclease is arrested when a redundant strand is completely assimi ...	1971	4934524
ultraviolet- and x-ray-induced responses of a deoxyribonucleic acid polymerase-deficient mutant of escherichia coli.	escherichia coli k-12, polal(-) is a mutant strain whose extracts are deficient in kornberg deoxyribonucleic acid (dna) polymerase activity. we have compared the mutant and parental strains on the basis of a number of responses to ultraviolet (uv) and x-irradiation. for both types of radiation, the mutant is more sensitive by approximately the same factor as measured by reduction in colony formation, depression of dna synthesis, and enhancement of dna degradation. the rate of repair of x-ray-ind ...	1971	4935330
a phage lambda endonuclease controlled by genes o and p.		1971	4937245
purification and properties of 3-deoxy-d-arabinoheptulosonic acid-7-phosphate synthetase (phe) from a lambda arog+ transductant of escherichia coli.	by incorporating arog, the structural gene for 3-deoxy-d-arabinoheptulosonic acid-7-phosphate (dahp) synthetase (phe), into the genome of a heat-inducible susr60 mutant of phage lambda, it has been possible to increase the intracellular levels of dahp synthetase (phe) in a lysogenized strain of escherichia coli some 15-fold over levels found in the wild-type strain. by using this strain, the enzyme has been purified approximately 2,000-fold compared with wild type, and various kinetic parameters ...	1971	4937786
polar mutations in the left arm of bacteriophage lambda i434.	by studying complementation between frameshift and nonsense mutants located in the structural genes for the head of bacteriophage lambdai434, we found mutations in gene b which are polar on genes c and d and one mutation in gene e which is polar on gene f.	1971	4927522
[induction of lambda phage and transduction in bacterial forms with changed synthesis of the cell wall].		1971	4938667
bacteriophage p2: interaction with phage lambda and with recombination-deficient bacteria.		1971	4943192
bacterial mutants in which the gene n function of bacteriophage lambda is blocked have an altered rna polymerase.	bacterial mutants have been isolated, called gron, that block phage development by interference with the action of the product of the phage n gene. lambdatrp phages, which depend on the n product for the synthesis of tryptophan enzymes, do not make these enzymes in gron bacteria. two type of phage mutants have been isolated that can overcome the gron block. one type makes an altered n product, the other contains an n-bypass mutation. the gron mutation is closely linked to the rifamycin-resistanc ...	1971	4943550
establishment and maintenance of repression by bacteriophage lambda: the role of the ci, cii, and c3 proteins.	to define the events necessary for the establishment and maintenance of repression in a lambda-infected cell, we have studied the requirements for efficient synthesis of the ci protein ("lambda-repressor"). three classes of lambda mutants defective in the establishment of repression are also defective in the appearance of ci protein activity at the normal time. two of these mutational classes (cii(-) and ciii(-)) probably result from inactivation of lambda-specified proteins, but the third class ...	1971	4943791
[the irreparability of damage caused by 1m hydroxylamine in lambda phage when submitted to passage in e. coli hcr+ and hcr- cells].		1970	4932341
light-induced cross-linking of dna in the presence of a furocoumarin (psoralen). studies with phage lambda, escherichia coli, and mouse leukemia cells.		1970	4927248
regulation of bacteriophage lambda development by gene n: properties of a mutation that bypasses n control of late protein synthesis.		1970	4909409
properties of phage lambda dna-rna polymerase complexes isolated from escherichia coli (lambda).		1970	4912207
crypticogenicity of bacteriophage lambda.		1970	4920426
effect of carbohydrates on induction of bacteriophage lambda.		1970	4920472
unbiased synthesis of pulse-labeled dna framents of bacteriophage lambda and t4.		1970	4922215
antigenic differences between wild type and mutants of bacteriophage lambda.		1969	4887235
the lysozyme of bacteriophage lambda. 3. ordering the cyanogen bromide peptides.		1969	4889462
protection and host cell repair of irradiated lambda phage. i. irradiation of normal phage with ultraviolet light.		1969	4897977
recombination in bacteriophage lambda. 3. studies on the nature of the prophage attachment region.		1969	4904107
two stages in the replication of bacteriophage lambda dna.		1969	4904393
mutants of bacteriophage lambda defective in vegetative genetic recombination.		1968	4938547
[the effect of cystamine and magnesium ions on the induction of moderate lambda phage by x-rays].		1968	4869266
[comparative characteristics of oxygen consumption and electrokinetic potential of escherichia coli under the effect of moderate and virulent coliphage. 1. effect of the induction of lambda-phage production on oxygen consumption and electrophoretic motility of e. coli k12 lambda].		1968	4873878
studies on radiation-sensitive mutants of e. coli. ii. breakage and repair of ultraviolet irradiated intracellular dna of phage lambda.		1968	4879098
absortive lysogenization of bacteriophage lambda b2 and residual immunity of non-lysogenic segregants.		1967	5340186
the formation of superinfection-double lysogens of phage lambda in escherichia coli k-12.		1965	5318339
effect of infection with phage lambda on the synthesis of protein, rna and dna in escherichia coli.		1964	14135546
recombination and phenotypic mixing during phage growth in strains of escherichia coli doubly lysogenic for coliphage lambda.		1958	13544106
interference phenomenon with lambda phage and cellular changes in induced e. coli, k12 (lambda) infected with t2 phage.		1956	13428420
[spontaneous induction of the development of bacteriophage lambda during genetic recombination in escherichia coli k12].		1954	13200000
[study of the lysogenization process of e. coli. i. single-cycle development curve of the temperate lambda phage and its virulent mutant lambda v in e. coli k12 s].		1954	13236148