Publications

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lambda phage mutants insensitive to temperature-sensitive repressor. ii. genetic character of lambda vir c mutant. 19705415250
a site essential for expression of all late genes in bacteriophage lambda. 19705418171
functional analysis of early defective mutants of coliphage lambda. 19705432279
effect of mutations in the c2 and c3 genes of bacteriophage lambda on macromolecular synthesis in infected cells. 19705453348
mutator gene action and the replication of bacteriophage lambda dna. 19705453351
nucleotide clusters in deoxyribonucleic acids. vi. the pyrimidine oligonucleotides of strands r and l of bacteriophage lambda dna. 19705485908
controls of rightward transcription in coliphage lambda. 19705492022
suppression of a mutant phenotype concerning head formation of bacteriophage lambda by the product of the lambda repressor gene. 19705424817
dna replication in head mutants of bacteriophage lambda. 19695357220
insertion of phage mu. 1 within prophage lambda. a new approach for studying the control of the late functions in bacteriophage lambda. 19695370121
induction and multiplication of lambda-phage. 3. the effect of hydroxyurea on heat induction. 19695377768
deoxyribonuclease iv: a new exonuclease from mammalian tissues.an exonuclease which specifically degrades double-standard dna has been isolated from rabbit tissues. the enzyme has an approximate molecular weight of 42,000, requires a divalent metal ion as cofactor, and attacks dna at the 5'-terminal ends, thereby liberating 5'-mononucleotides. it degrades several synthetic polydeoxynucleotides of single repeating base sequences more rapidly than dna from natural sources. the specificity of this mammalian enzyme resembles that of several microbial enzymes (p ...19695256235
in vitro polymerization of bacteriophage lambda tails. 19695344290
the biosynthesis of phage lambda dna. 19695372867
lambda phage mutants insensitive to temperature-sensitive repressor. i. isolation and genetic analysis of weak-virulent mutants. 19695804682
mapping of deletions and substitutions in heteroduplex dna molecules of bacteriophage lambda by electron microscopy.electron microscopy of heteroduplex dna molecules, composed of one strand of escherichia coli phage lambda(+) dna annealed to the complementary dna strand of a lambda deletion or substitution mutant, permits visualization, as well as precise measurements and mapping, of the unpaired single-stranded regions of nonhomology in the otherwise double-stranded molecules. in the lambdab2 mutant, the central segment (13 percent) of the lambda(+) dna molecule is shown to be deleted. in the hybrid phages l ...19695765116
orientation and control of transcription in e. coli phage lambda. 19695765054
patterns of convergent and overlapping transcription within the b2 region of coliphage lambda. 19695803945
membrane association by bacteriophage lambda-dna: possible direct role of regulator gene n. 19695806995
inactivation of bacteriophage lambda containing semiconserved alkylated deoxyribonucleic acid.immediate and delayed inactivation of ethylmethane sulfonate (ems)-treated lambda phage were studied. phage particles with one alkylated and one intact deoxyribonucleic acid (dna) strand were obtained by allowing host-modified, ems-treated phage to undergo one growth cycle in a nonmodifying host and selecting the progeny with semiconserved parental dna on a restricting host. the results indicate that particles with one alkylated dna strand are more sensitive to a second treatment with the alkyla ...19695823226
genetic mapping of an endonuclease synthesized by bacteriophage lambda. 19695799035
the effect of proflavine on the vegetative reproduction of bacteriophage lambda. 19695804680
[photosuppression of mitomycin-induced lambda-phage development]. 19695815265
the mechanism of restriction of bacteriophage lambda in escherichia coli strains: demonstration of an in vivo requirement for s-adenosylmethionine. 19694897045
effect of u.v.-irradiated dna containing 5-bromouracil on reactivation u.v. damage in phage lambda. 19694905876
protection and host cell repair of irradiated lambda phage. ii. irradiation of 5-bromouracil-substituted phage with near visible light. 19694897978
nonessential functions of bacteriophage lambda. 19694974326
antigenic differences between wild type and mutants of bacteriophage lambda. 19694887235
the lysozyme of bacteriophage lambda. 3. ordering the cyanogen bromide peptides. 19694889462
induction and multiplication of lambda-phage. iv. the effect of panfuran. 19694911436
ring opening of covalent lambda phage dna circles after thermal induction of superinfected lysogens: control by gene n. 19694889432
the lysozyme of bacteriophage lambda. i. purification and molecular weight. 19694889461
protection and host cell repair of irradiated lambda phage. 3. ultraviolet irradiation of 5-bromouracil-substituted phage. 19694897979
a search for cooperative infection of p1-lysogenic escherichia coli by restricted lambda phage. 19694896156
protection and host cell repair of irradiated lambda phage. i. irradiation of normal phage with ultraviolet light. 19694897977
characteristics of some multiply recombination-deficient strains of escherichia coli.strains of escherichia coli have been made carrying lesions in more than one gene determining recombination. the following genotypes were constructed and verified: recc22 recb21 reca(+), recc22 recb21 reca13, recc22 recb(+)reca13, and recc(+)recb21 reca13. all multiple rec(-) strains carrying reca13 were similar to ab2463, which carries reca13 alone, in their uv sensitivities, recombination deficiencies, and inabilities to induce lambda phage in a lysogen. however, whereas ab2463 shows a high ra ...19694898990
leakiness of pleiotropic maltose-negative, bacteriophage lambda-resistant mutants of escherichi coli k-12.cultures of escherichia coli k-12 mala(-)lambda(r)gal(-) can be transduced to gal(+) by bacteriophage lambdadg because of leakiness of the lambda(r) phenotype. the efficiency of such transduction is about 10(-5) that of transduction of mal(+)lambda(s) bacteria. leaky cells (lambda(s)phenocopies) adsorb only very few phage particles, and many transductants, therefore, are defective heterogenotes or show integration of the gal(+) gene, which is unaccompanied by lysogenization.19694905538
induction of phage lambda by transferred irradiated coli dna. 19694905437
loss of host-controlled restriction and modification of phage lambda in escherichia coli k12 previously infected with uv-irradiated coli-phage dt3. 19694891221
new mutations in the s cistron of bacteriophage lambda affecting host cell lysis. 19694891223
strains of phage lambda in current use. 19694891412
the effect of 5-aminoacridine on the vegetative reproduction of bacteriophage lambda. 19694891743
the steric effect in lysogenization by bacteriophage lambda. iv. superinfection of nonimmune lysogens. 19694887934
chromosome mobilization in rec-merodiploids of escherichia coli k12 following infection with bacteriophage lambda. 19694902068
alteration of rna polymerase during transcription of phage lambda dna "in vivo". 19694902783
recombination in bacteriophage lambda. 3. studies on the nature of the prophage attachment region. 19694904107
the integration and excision defect of bacteriophage lambda-dg. 19694904108
two stages in the replication of bacteriophage lambda dna. 19694904393
role of host rna polymerase for lambda phage development. 19694390186
isolation and base composition of sites on lambda phage dna which bind with rna polymerase of escherichia coli. 19694306141
the lysozyme of bacteriophage lambda. ii. amino acid and end group analysis. 19694181160
structure and base sequence in the cohesive ends of bacteriophage lambda dna. 19684299833
[action of ultraviolet rays on bacteriophage lambda]. 19684174324
studies on head-tail union in bacteriophage lambda. 19684882733
replication of phage lambda dna. 19684891991
[comparative characteristics of oxygen consumption and electrokinetic potential of escherichia coli under the effect of moderate and virulent coliphage. 1. effect of the induction of lambda-phage production on oxygen consumption and electrophoretic motility of e. coli k12 lambda]. 19684873878
sedimentation of dna from bacteriophage lambda-infected escherichia coli. 19684881148
the effect of amino acids on host-controlled restriction of lambda phage. 19684876151
mutants of phage lambda unable to exclude phage t4rii. 19684878024
cis-trans position effect of certain genes controlling tail protein in bacteriophage lambda. 19684881035
effect of ribonucleic acids on the infectivity of phage lambda dna. 19684881146
evidence for independent segregation of the escherichia coli chromosome and non-replicating bacteriophage lambda b2. 19684868426
effect of mutation to streptomycin resistance on amber suppressor genes.three classes of nonidentical streptomycin-resistant mutations were distinguished in escherichia coli by their effect on the efficiency of suppression by an amber suppressor gene, sup e. the first class of mutation caused a strong restriction in efficiency of suppression of an amber codon in various cistrons of phage lambda and in an alkaline phosphatase structural gene of e. coli. the second class caused weak restriction, and the third class caused no restriction. the restrictive effect of the ...19684874314
properties of mitomycin c-sensitive mutants of escherichia coli k-12.strains hypersensitive to mitomycin c (mc) were isolated from escherichia coli k-12 after treatment with nitrosoguanidine. of 43 mc-sensitive strains tested for their ultraviolet light (uv) sensitivity and for their ability to reactivate uv-inactivated lambda phage, 38 were found to be insensitive to uv irradiation and to be able to reactivate uv-irradiated bacteriophage lambda. some properties of the mc-sensitive, uvr(+) mutants were analyzed. synthesis of deoxyribonucleic acid (dna) in mc-sens ...19684867746
effect of lysogeny on serum sensitivity.when escherichia coli k-12 was infected with lambda phage and mutants of lambda characterized by the production of temperature-sensitive repressors, the lysogenic bacteria were significantly more resistant to normal serum than the uninfected organisms. infection of e. coli k-12 with a lambdoid phage, phi80, whose prophage attachment site is different from that of lambda, did not result in a detectable change in serum resistance. similarly, infection with certain pseudomonas and shigella phages c ...19684881698
segmental distribution of nucleotides in the dna of bacteriophage lambda. 19684999721
replication of bacteriophage dna. i. replication of dna of lambda phage defective in early functions. 19684941475
the role of the n gene of phage lambda in the synthesis of two phage-specific proteins. 19684973489
mechanism ofhost-controlled restriction of bacteriophage lambda by r factors in escherichia coli k12. 19684867907
production of single-strand breaks in covalent circular lambda phage dna in superinfected lysogens by monoalkylating agents and the joining of broken dna strands. 19684878021
studies on radiation-sensitive mutants of e. coli. ii. breakage and repair of ultraviolet irradiated intracellular dna of phage lambda. 19684879098
relationship between k-reactivation and uv-reactivation of bacteriophage lambda. 19684879191
mutants of bacteriophage lambda defective in vegetative genetic recombination. 19684938547
physiology of bacteriophage lambda in the restrictive host. 19684938540
attachment and detachment of bacteriophage lambda dna in lysogenization and induction. 19684868761
[the effect of cystamine and magnesium ions on the induction of moderate lambda phage by x-rays]. 19684869266
photosuppression of mitomycin-induced lambda-phage development. 19684869715
evidence for a new endonuclease synthesized by lambda bacteriophage.infection of nonlysogenic escherichia coli cr34(s) (thy(-)) with bacteriophage lambda c(i)857 resulted in the formation of twisted circular double-stranded phage deoxyribonucleic acid (dna; species i). when such infected bacteria were incubated in the absence of thymine, there was a significant decrease in the amount of species i dna after 60 min of incubation. a similar loss of species i lambda dna during incubation in a thymine-deficient medium was also observed after infection of the endonucl ...19685723713
induction and multiplication of lambda-phage. ii. the effect of valine and leucine. 19685679785
disruption of t-even bacteriophages by dimethyl sulfoxide.dimethyl sulfoxide (dmso) disrupted t-even bacteriophages as well as lambda bacteriophage. the component substructures of t2l, t4b01, or t6, in particular heads, were readily isolated after treatment with 67% dmso (v/v). in contrast, concentrations of dmso above 50% not only separated heads from tails of bacteriophage lambda but led to degradation of the lambda heads. examination of the isolated free heads of t-even bacteriophage indicated that a distinct neck substructure was attached to one ap ...19685697471
recombination in bacteriophage lambda. ii. site-specific recombination promoted by the integration system. 19685760459
genetic transcription in bacteriophage lambda: studies of lambda m rna synthesis in vivo. 19685719216
integration-negative mutants of bacteriophage lambda. 19685637199
mutations in bacteriophage lambda affecting particle morphogenesis. 19685652675
studies on the genetics of biotin-transducing, defective variants of bacteriophage lambda. 19685669988
recombination in bacteriophage lambda. i. mutants deficient in general recombination. 19685760458
studies of the messenger rna of bacteriophage lambda, i. various species synthesized early after induction of the prophage. 19685246538
the regulation and mechanism of dna synthesis in bacteriophage lambda. 19685254585
the integration and excision of the bacteriophage lambda genome. 19685254582
the general recombination system of bacteriophage lambda. 19685254579
site-specific recombination in bacteriophage lambda. 19685254580
integration, excision, and transducing particle genesis by bacteriophage lambda. 19685254581
in vitro repression of phage lambda dna transcription by a partially purified repressor from lysogenic cells. 19685238651
replication of bacteriophage dna, ii. structure of replicating dna of phage lambda. 19685243927
the operators controlled by the lambda phage repressor. 19685244737
gene orientation in bacteriophage lambda as determined from the genetic activities of heteroduplex dna formed in vitro. 19685700418
genetics of the left arm of the chromosome of bacteriophage lambda. 19685705826
integrative recombination function of bacteriophage lambda: evidence for a site-specific recombination enzyme. 19685760457
[elimination of t4rii by c-mutants of the lambda phage]. 19685745532
host survival following infection with or induction of bacteriophage lambda mutants.the lethal effects of lambda infection and lambda induction were studied using conditional lethal mutants of phage lambda in the su- host w3350. phage with mutations in q and r, which are blocked after dna replication, kill promptly and efficiently on induction or infection. infection with mutants defective in o and p, which do not replicate, kills less efficiently, although these mutants do kill effectively at high multiplicity of infection. heat induction of lysogens carrying dna defective mut ...196818614112
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