Publications

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early detection of inhaled anthrax infection: nuclear medicine investigational nod. 200111776251
anthrax: u.s. bioterrorism affecting missourians. 200111778308
anthrax prophylaxis, treatment, and reporting guidelines. 200111778309
what you need to know about anthrax today. 200111778310
the psychosocial aspect of the anthrax vaccine: "the dover experience". 200111778428
wake-up call: a bioterrorism exercise.operation wake-up call was a simulated bioterrorism exercise conducted in waukesha county, wisconsin (metropolitan milwaukee) on november 6, 1999. the purpose of the exercise was to test and evaluate the emergency response capability of local municipal, county, state, federal, and reserve military agencies to a weapons of mass destruction terrorist act. the exercise simulated a biological agent (bacillus anthracis spores) release, a hostage-taking event, and the management of multiple biological ...200111778452
tracking & treating anthrax. biological terrorism resources for health care providers. 200111778462
delivering death in the mail. 200111780023
agents of bioterrorism. preparing for bioterrorism at the community health care level.bioterrorism preparedness is clearly a goal for the health care community, working in concert with city, county, state, and federal public health and emergency authorities and in collaboration with law enforcement at the local and federal levels. opening the channels of communication between all groups involved, obtaining the necessary resources, and maintaining an understanding of the potential agents and the diseases they cause will foster a smooth transition to a rational program directed at ...200111780270
from the centers for disease control and prevention. investigation of anthrax associated with intentional exposure and interim public health guidelines, october 2001. 200111757496
from the centers for disease control and prevention. recognition of illness associated with the intentional release of a biologic agent. 200111757497
from the centers for disease control and prevention. update: investigation of bioterrorism-related anthrax and interim guidelines for exposure management and antimicrobial therapy, october 2001. 200111757528
cdc issues guidelines on illnesses associated with intentional release of biologic agents. 200111759081
anthrax: a primer for practitioners. 200111759435
anthrax vaccine: what you need to know. 200111759436
evaluating the threat. 200111759581
from the centers for disease control and prevention. investigation of bioterrorism-related anthrax and interim guidelines for clinical evaluation of persons with possible anthrax. 200111759667
from the centers for disease control and prevention. updated recommendations for antimicrobial prophylaxis among asymptomatic pregnant women after exposure to bacillus anthracis. 200111759668
from the centers for disease control and prevention. interim recommendations for protecting workers from exposure to bacillus anthracis in work sites in which mail is handled or processed. 200111759669
smallpox and anthrax vaccine information. 200111760366
[anthrax. description of symptoms, findings, diagnostics and treatment of infection]. 200111760546
[anthrax transmission from patient to patient?]. 200111760547
bioterrorism. implications for the occupational and environmental health nurse.1. bioterrorism is the intentional release of a biological agent--bacterial, viral, or genetically altered--to instill fear or create chaos, massive casualities, illness, and death in humans, animals, or plants. 2. the threat of bioterrorism is real. although every community is vulnerable, terrorists seek densely populated, highly visible targets. 3. occupational and environmental health nurses must to be able to recognize and report signs and symptoms of an early bioweapons outbreak in their wo ...200111760706
overlooked in cipro hype: other anti-anthrax meds. 200111761591
wv department of health and human services. information for physicians: anthrax. 200111761656
how much is enough? aha, lawmakers debate federal funding for bioterrorism preparation.the anthrax outbreak was just the beginning. recently the nation's hospitals got their first taste of dealing with a bioterrorism attack. and as fears of different terrorist onslaughts escalate, healthcare providers struggle to answer questions they never faced before--and to anticipate new ones.200111761733
anthrax: walking the fine line between precaution and panic. 200111762587
clinicians must be voice of reason, reassurance now that bioterrorism battle has been joined. 200111763593
cdc broadcast aims to improve clinicians' grasp of anthrax issues. 200111763795
special health care team screens postal workers for anthrax. 200111763796
ciprofloxacin frenzy. 200111763803
pharmacy preparedness for incidents involving weapons of mass destruction.recent worldwide terrorist acts and hoaxes have heightened awareness that incidents involving weapons of mass destruction (wmd) may occur in the united states. with federal funding assistance, local domestic preparedness programs have been initiated to train and equip emergency services and emergency department personnel in the management of large numbers of casualties exposed to nuclear, biological, or chemical (nbc) agents. hospital pharmacies will be required to provide antidotes, antibiotics ...200111763806
from the centers for disease control and prevention. investigation of bioterrorism-related anthrax and adverse events from antimicrobial prophylaxis. 200111763846
from the centers for disease control and prevention. considerations for distinguishing influenza-like illness from inhalational anthrax. 200111763847
from the centers for disease control and prevention. interim guidelines for investigation of and response to bacillus anthracis exposures. 200111763848
jama patient page. anthrax. 200111763849
from the centers for disease control and prevention. investigation of bioterrorism-related anthrax, 2001. 200111763854
from the centers for disease control and prevention. recommendations for antimicrobial prophylaxis for children and breastfeeding mothers and treatment of children with anthrax. 200111763855
cdc updates interim guidelines for anthrax exposure management and antimicrobial therapy. 200111764868
september 11. 200111765105
biological and chemical terrorism: recognition and management.primary care physicians will be on the front line in detecting and managing any future terrorist attacks that use chemical or biological agents. this article reviews how to recognize and treat disease caused by exposure to nerve agents, blistering agents, hydrogen cyanide, ricin, anthrax, smallpox, plague, and botulinum toxin.200111765118
bioterrorism: an unintended boost to public health? 200111765120
bioterrorism: what practicing physicians can do. 200111765124
cashing in on fear. 200111765372
[anthrax and carbuncle].anthrax is a name given in french language to two distinct infectious diseases. one corresponds to carbuncle which is a collection of boils. the other one corresponds to the english term anthrax. this condition has a clinical presentation and an outcome that vary according to the inoculation site being cutaneous, pulmonary or digestive, and to the bacterial and toxin spread in the body.200111765578
bioterrorism: defending the public's health in a time of national crisis. 200111765711
pasteur returns. 200111766555
anthrax. 200111766556
old biological threats. 200111766557
the anthrax detectives. 200111767897
anthrax, bioterrorism fears stimulate immune, other research. 200111768882
are you ready for anthrax, or worse? you must revamp your bioterrorism plan.a study has shown that eds are unprepared to handle mass casualties of bioterrorism, and plans must be revamped. alternate care and triage areas must be selected in advance and may include parking lots and hallways between buildings. care for contaminated patients in areas that can be abandoned, so regular patient care areas are not disrupted. have a system in place to decontaminate patients before they enter the ed.200111769134
[infectious diseases as a weapon: vigilance is needed].the deliberate inclusion of bacillus anthracis spores in mail has led to several cases of anthrax in the usa of which to date four have been fatal. shortly before these incidents, the health council of the netherlands had issued an advisory document which stressed the need for a well-established infrastructure and rigorous protocols so that an immediate and adequate response to cases of bioterrorism could be ensured. physicians are expected to know the characteristics of the relevant diseases an ...200111770262
[anthrax due to deliberate infection].anthrax is a zoonosis which is particularly prevalent in cattle, goats and sheep and is caused by bacillus anthracis, a gram-positive spore forming aerobic microorganism. the endospores can survive outside of the body for many decades. the natural form of anthrax has a cutaneous, pulmonary and intestinal form. the pulmonary form can be rapidly fatal but is difficult to recognise due to an initially non-specific, flu-like clinical picture. as a result of spores being inhaled, a mediastinal lympha ...200111770263
[female patient with cutaneous anthrax in belgium].a 23-year-old turkish woman was admitted with an infection of the left thumb. the clinical picture was typical for cutaneous anthrax. microbiological tests confirmed the diagnosis 'infection by bacillus anthracis'. she recovered when treated with penicillin, although later tests revealed that the bacteria were resistant to this antibiotic. the patient became infected in belgium as a result of wounding herself on the teeth of an illegally slaughtered sheep, which had possibly become infected in t ...200111770267
update: investigation of bioterrorism-related anthrax--connecticut, 2001.cdc and state and local health departments continue investigating cases of bioterrorism-related anthrax. this report revises the number of suspected cases and updates the investigation of a 94-year-old connecticut (ct) resident who died from inhalational anthrax.200111770501
use of onsite technologies for rapidly assessing environmental bacillus anthracis contamination on surfaces in buildings.environmental sampling to ascertain the presence of bacillus anthracis spores in buildings is an important tool for assessing risk for exposure. similar to diagnostic testing, culture with positive identification of b. anthracis (cdc culture method) is the confirmatory test. laboratory-based polymerase chain reaction (pcr) methods for detecting genetic material of b. anthracis can be used in preliminary assessments and as adjuncts to microbiologic methods. although these tests are consistent wit ...200111770505
systemic toxins. signs, symptoms & management of patients in septic shock. 200111771375
is anthrax the next lyme disease? 200111771484
sketchy isn't best. hospitals fault feds for poor anthrax guidance. 200111715739
how little we really know. 200111715747
life on alert. nation remains jittery as threats keep coming. 200111715791
cdc has anthrax, smallpox vaccination guidelines available. 200111715817
clueless in manhattan. 200111715865
counting deadly spores. 200111715866
bugs, bared. genome sequences of killer microbes reveal the arsenals of infection. 200111715870
[this concerns your patients. how does one recognize anthrax? (interview by dr. roland knauer)]. 200111715871
who should get flu shots? 200111715913
anthrax. the mystery deepens. 200111715914
anthrax as a cancer drug? 200111717324
crystallization and preliminary x-ray study of the edema factor exotoxin adenylyl cyclase domain from bacillus anthracis in the presence of its activator, calmodulin.edema factor from bacillus anthracis is a 92 kda secreted adenylyl cyclase exotoxin and is activated by the host-resident protein calmodulin. calmodulin is a ubiquitous intracellular calcium sensor in eukaryotes and activates edema factor nearly 1000-fold upon binding. while calmodulin has many known effectors, including kinases, phosphodiesterases, motor proteins, channels and type 1 adenylyl cyclases, no structures of calmodulin in complex with a functional enzyme have been solved. the crystal ...200111717504
hyping bioterrorism obscures real concerns. 200111718116
bioterrorism in the united states: take it seriously. 200111718117
the loss of innocence. 200111718352
anthrax: a motor protein determines anthrax susceptibility.a new study has found that polymorphisms in the host gene kif1c, which encodes a kinesin-like motor protein, determine whether mouse macrophages are resistant or sensitive to anthrax lethal toxin. these findings may lead the way to discovering how both germ and host factors might contribute to a lethal infection.200111719234
clinical presentation of inhalational anthrax following bioterrorism exposure: report of 2 surviving patients.the use of anthrax as a weapon of biological terrorism has moved from theory to reality in recent weeks. following processing of a letter containing anthrax spores that had been mailed to a us senator, 5 cases of inhalational anthrax have occurred among postal workers employed at a major postal facility in washington, dc. this report details the clinical presentation, diagnostic workup, and initial therapy of 2 of these patients. the clinical course is in some ways different from what has been d ...200111722268
death due to bioterrorism-related inhalational anthrax: report of 2 patients.on october 9, 2001, a letter containing anthrax spores was mailed from new jersey to washington, dc. the letter was processed at a major postal facility in washington, dc, and opened in the senate's hart office building on october 15. between october 19 and october 26, there were 5 cases of inhalational anthrax among postal workers who were employed at that major facility or who handled bulk mail originating from that facility. the cases of 2 postal workers who died of inhalational anthrax are r ...200111722269
bioterrorism on the home front: a new challenge for american medicine. 200111722275
optimization of an oligonucleotide microchip for microbial identification studies: a non-equilibrium dissociation approach.the utility of a high-density oligonucleotide microarray (microchip) for identifying strains of five closely related bacilli (bacillus anthracis, bacillus cereus, bacillus mycoides, bacillus medusa and bacillus subtilis) was demonstrated using an approach that compares the non-equilibrium dissociation rates ('melting curves') of all probe-target duplexes simultaneously. for this study, a hierarchical set of 30 oligonucleotide probes targeting the 16s ribosomal rna of these bacilli at multiple le ...200111722542
[bacillus anthracis, an old friend in a new appearance?]. 200111723811
something she called a fever: michelet, derrida, and dust. 200111724069
update: investigation of bioterrorism-related anthrax and adverse events from antimicrobial prophylaxis.cdc and state and local public health authorities continue to investigate cases of bioterrorism-related anthrax. as of november 7, a total of 22 cases of anthrax have been identified according to the cdc surveillance case definition; 10 were confirmed inhalational anthrax cases and 12 cases (seven confirmed and five suspected) were cutaneous anthrax (table 1). the majority of cases have occurred in persons working at postal facilities in new jersey (nj) and the district of columbia (dc) in which ...200111724150
considerations for distinguishing influenza-like illness from inhalational anthrax.cdc has issued guidelines on the evaluation of persons with a history of exposure to bacillus anthracis spores or who have an occupational or environmental risk for anthrax exposure. this notice describes the clinical evaluation of persons who are not known to be at increased risk for anthrax but who have symptoms of influenza-like illness (ili). clinicians evaluating persons with ili should consider a combination of epidemiologic, clinical, and, if indicated, laboratory and radiographic test re ...200111724153
interim guidelines for investigation of and response to bacillus anthracis exposures.environmental sampling. environmental testing to detect b. anthracis on surfaces or in the air can be used to investigate known or suspected exposure events. the highest priority of an investigation is to evaluate the risk for exposure to aerosolized b. anthracis spores. persons collecting and testing samples should 1) obtain adequate samples, 2) avoid cross-contamination during processing, and 3) ensure proficient laboratory testing and interpretation of test results. a positive laboratory test ...200111724154
update: investigation of bioterrorism-related anthrax, 2001.this report updates the investigation of bioterrorism-related anthrax and the provision of antimicrobial prophylaxis to exposed persons and highlights cdc assistance to other countries investigating cases of bioterrorism-related anthrax. since november 7, 2001, cdc and state and local public health agencies have identified no new cases of bioterrorism-related anthrax. as of november 14, a total of 22 cases of anthrax has met the cdc case definition; 10 were confirmed inhalational anthrax, and 12 ...200111724158
update: interim recommendations for antimicrobial prophylaxis for children and breastfeeding mothers and treatment of children with anthrax.ciprofloxacin or doxycycline is recommended for antimicrobial prophylaxis and treatment of adults and children with bacillus anthracis infection associated with the recent bioterrorist attacks in the united states. amoxicillin is an option for antimicrobial prophylaxis for children and pregnant women and to complete treatment of cutaneous disease when b. anthracis is susceptible to penicillin, as is the case in the recent attacks. use of ciprofloxacin or doxycycline might be associated with adve ...200111724160
molecular investigation of the aum shinrikyo anthrax release in kameido, japan.in 1993, the aum shinrikyo cult aerosolized bacillus anthracis spores over kameido, japan. spore samples were obtained from the release site, cultured, and characterized by molecular genetic typing. the isolates were consistent with strain sterne 34f2, which is used in japan for animal prophylaxis against anthrax.200111724885
bioterrorism watch. clinicians must be voice of reason, reassurance now that bioterrorism battle has been joined. 200111725496
rapid anthrax test developed. 200111726951
bioterrorism: a clear and present danger. 200111726956
'we're all working together.' new york-area hospitals redouble efforts in face of anthrax death.the death of a new york hospital worker from inhalation anthrax last week put new strains on an overburdened public health system. the fact that no source of the bacteria could be found only added to the difficulties. hospitals along the east coast battled clinical, logistical and financial problems from the outbreak.200111727463
bleach, gas, or foam? 200111727474
early and aggressive treatment saves us anthrax victims. 200111728555
taking anthrax's genetic fingerprints. 200111729278
anthrax. can lab sleuths clinch the case? 200111729279
a second anthrax genome project. 200111729280
anthrax. a 'sure killer' yields to medicine. 200111729281
us anti-bioterror efforts swiftly expanding. 200111731763
fate of germinated bacillus anthracis spores in primary murine macrophages.we investigated the fate of germinated bacillus anthracis spores after their germination in swiss murine peritoneal macrophages and in the cell line raw264.7. we found that the lethal toxin and the oedema toxin are germ-associated factors that are essential for the survival of the vegetative form in host cells. we also found that px02 is not involved in this complex pathogenic process. by transmission electron microscopy, we showed the tight interaction between the exosporium of the spore and th ...200111737637
cutaneous anthrax: still a reality in india. 200111737702
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