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1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine, a new drug with marked activity against entamoeba histolytica. short communication.1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine (hoe 316) administered orally produces an effect which is clearly superior to that of metronidazole against entamoeba histolytica in the golden hamster and slightly inferior against trichomonas fetus and t. vaginalis in the mouse. the acute tolerance of the compound is very good (ld 50% greater than 10 g/kg body weight). it is assumed that the possible main metabolite of hoe 316 is a monohydrazone: 1-methyl-2-(4-amino-piperazino- ...1977195590
some reactions in which inorganic pyrophosphate replaces atp and serves as a source of energy. 1977195842
amebic granuloma--an experimental study.the etiopathogenesis of granuloma formation in amebiasis is not known. an experimental study was carried out in 48 guinea pigs arranged into four groups, to assess the role of hypersensitivity in formation of amebic granuloma. repeated intracecal inoculations of saline in group i and mixed amebic and bacterial suspension in other groups were made. animals in group iii were sensitized by amebic antigen and in group iv by bacterial antigen before inoculations. lesions produced in the amebic hypers ...1977199058
[cytochemical labeling of proteolytic enzymes in entamoeba histolytica].trophozoites were obtained from fecal mucous in patients bearing colonic amebiasis. the tripsin inhibitor of soya bean was coupled to peroxidase according to nakane and kawokoi method. amebae were incubated with couple and reactions were developed following karnowsky's technic. there was a specific labeling of proteolitic enzymes on plasma membrane, the wall of digestive vacuoles and intracytoplasmic vacuoles of the trophozoites. such a distribution of proteolitic enzymes agreed with digestive a ...1977199123
amoebic serology vs appendicular lumps. 1977199568
[amebic abcess of the liver analysis of 7 cases (author's transl)]. 1977199928
[invading intestinal amebiasis in infants (author's transl)]. 1977199929
qualitative x-ray spectrometric study of e. histolytica trophozoite nuclei.qualitative x-ray energy spectroscopical analysis was performed in two strains of entamoeba histolytica trophozoites: hk-9; nih strain, and hm-2; imss strain, cultured in axenic and monoxenic conditions, respectively. the trophozoites were fixed in buffered-glutaraldehyde, embedded in epon, thick sectioned )50-200 nm), and mounted on nickel grids. x-ray emissions were analyzed with an ortec x-ray energy detector and multichannel and analyzer adapted to a transmission electron microscope. the stu ...1977200194
[chemical and pharmacologic study on pyran derivatives. ix. synthesis of 2-dialkylaminochromones].under suitable conditions the reaction of phenol and n,n-dialkylethoxycarbonylacetamides, in the presence of phosphorus oxychloride, resulted in the formation of 2-dialkylaminochromones. in a similar manner, variously substituted phenols afforded 2-dialkylaminochromones with substituents in different positions of the benzene ring. pharmacological screening of all these compounds showed that they markedly affect the cns, activity being mainly excitatory. decreased activity was shown by compounds ...1977200470
surface features of entamoeba histolytica and rabbit kidney (rk13) cell surface changes after trophozoite contact--observations by scanning electron microscopy. 1977200580
[synthesis and amoebicid properties of emetin analogs. analysis of the new compounds by 13c-nmr. b/c-cis or trans-fused (+/-) 1-alkyl-3-desethyl-emetin (author's transl)]. 1977200588
[value of sensitization of adult albino rats with amebic antigen before their inoculation with the culture of entamoeba histolytica]. 1977200834
virulence and toxicity of axenic entamoeba histolytica. 1977189211
[possibilities and problems in the laboratory diagnosis of amebiasis]. 1977189237
symposium on diarrhea. 3. investigation of chronic diarrhea.the practical approach to the investigation of diarrhea must be logical and based on anatomic considerations. the site of the underlying disorder may be determined by the clinical picture, and the logic of investigation will be influenced by the history. important specific investigation in a case of colonic diarrhea include a careful rectal examination, stool inspection, sigmoidoscopy, rectal biopsy and barium enema study. colonoscopy has been used, but its role has yet to be defined. in a case ...1977191173
perforation of the colon in unsuspected amebic colitis: report of two cases.two cases of amebic colitis that resulted in perforation of the colon, an ominous complication, are presented. the first was diagnosed preoperatively as acute ulcerative colitis with toxic megacolon, and the second as peritonitis complicating acute cholecystitis. in both instances the correct diagnosis was made after operation. the first patient recovered after colectomy and antiamebic therapy, but the second patient died in the early postoperative period, in septic shock. amebic colitis occurs ...1977191233
entamoeba histolytica: membrane fractions. 1977191274
selective coeliac angiography in amebic liver abscess. 1977191555
cultivation of entamoeba histolytica as a diagnostic procedure: a brief review. 1977191743
[diagnostic significance of identification of anti-entamoeba histolytica antibodies (author's transl)].examinations were performed with the indirect immunofluorescence test (ifat) and the indirect haemagglutination test (ihat). negative titers (less than 1:5) do not exclude an infection with e. histolytica. titers up to 1:80 in both reactions are found in patients with negative stool specimens or indicate an asymptomatic infection of the intestinal lumen, an incipient or past symptomatic amoebiasis. ifat values of 1:160 together with a negative or positive ihat are also suggestive of the two last ...1977191745
parasitic infections in black children in an endemic schistosomiasis area in natal.urine and stool specimens from 856 school children aged from 7 to 20 years, and from 80 preschool children, were examined for schistosoma haematobium and intestinal helminths and protozoa. s. haematobium was present in 57% with a peak of 81% in 13-14-year-old children. peak intensity preceded peak incidence and egg loads gradually decreased with age. there was no clear-cut difference between boys and girls with regard to intestinal parasites, nor was there a close correlation between the inciden ...1977191941
an in vitro model for measuring the cytopathic effect of entamoeba histolytica. 1977192877
an energy-conserving pyruvate-to-acetate pathway in entamoeba histolytica. pyruvate synthase and a new acetate thiokinase.under anaerobic conditions, cells of entamoeba histolytica grown with bacteria produce h2 and acetate while cells grown axenically produce neither. aerobically, acetate is produced and o2 is consumed by amebae from either type of cells. centrifuged extracts, 2.4 x 106 x g x min, from both types of cells contain pyruvate synthase (ec 1.2.7.1) and an acetate thiokinase which, together, form a system capable of converting pyruvate to acetate. pyruvate synthase catalyzes the reaction: pyruvate + coa ...197713076
entamoeba histolytica: diaphorase activities. 197714017
partial purification and some properties of a neutral sulfhydryl and an acid proteinase from entamoeba histolytica.the partial purification of two intracellular proteinases from the protozoan parasite entamoeba histolytica is reported. one of these enzymes is an acid proteinase exhibiting maximum activity at ph 3.5 (hemoglobin substrate), is little affected by a range of inhibitors or activators, and is presumed to be similar to cathepsin d. also present is a neutral proteinase exhibiting optimum activity at ph 6.0 (azocasein) but only poorly hydrolyzing either hemoglobin or serum albumen. this latter enzyme ...197716691
ph and entamoeba histolytica. 197724290
fractionation and serological characterization of entamoeba histolytica antigen. 197784508
[unified methods of laboratory studies. clinical laboratory parasitology. methods of examination of biological material for the presence of protozoa]. 197771390
immunoperoxidase staining of e. histolytica and soil amebas in formalin-fixed tissue. 197771856
detection & characterization of humoral antibodies from amebic immune sera. 1977207638
presence of prostaglandins a & e in entamoeba hystolytica. 1977207640
pathogenicity of entamoeba histolytica--virulence of strains of amoebae from symptomatic and asymptomatic cases of amoebiasis. 1977205504
[amebic liver abscess draining into the pericardium. report of a case with favorable outcome]. 1977205181
an evaluation of the absorption spectra of antigens from entamoeba histolytica (ibadan strains).by means of chromatography different fractions of antigens from entamoeba histolytica (ibadan strains) have been separated. all the different fractions have been tested for antigenic reactivity using agar gel diffusion technique. the intact antigen, as well as, the three antigenically reactive fractions were found to have ultra-violet absorption spectra in the region 258 and 278 millimicron. by virtue of this physico-chemical property amoebic extract(s) was found to simulate a mononucleotide deo ...1977209678
biomedical survey in irian jaya (west irian), indonesia.a biomedical survey was conducted in several areas of irian jaya, indonesia in july 1972 in association with an investigation of reports of a cholera outbreak. stool specimens, blood smears and sera were collected and examined for evidence of parasitic as well as other infectious diseases. a total of 114 stools were examined and the most commonly found intestinal parasites were trichuris trichiura (94%), ascaris lumbricoides (74%), hookworm (58%), entamoeba coli (15%), endolimax nana (8%), entam ...1977208184
new indolic cysticidal agents.from a series of compounds having amino acid esters linked into the 3 position of substituted indole 3-acetic acids only the compounds 2 and 6 have shown promizing biological activity where as compound 2 process excystment property only, compound 6 has shown both excystment and cysticidal properties. all other compounds are inactive.1977206917
[pathogenesis of amebiasis. ii. endoscopy and histopathology of the rectosigmoid mucosa in intestinal amebiasis]. 1977206948
[pathogenesis of amebiasis. iii. serological tests in patients infected with entamoeba histolitica]. 1977206949
heat-labile enterotoxigenic escherichia coli and intestinal protozoa in asymptomatic travellers.thirty-two asymptomatic travellers who had recently journeyed in the near, middle, and far east and had experienced a high incidence of diarrhoeal disease were screened for heat-labile enterotoxigenic escherichia coli (ent+ e. coli) and other bacterial and parasitic pathogens. six percent were colonized with ent+ e. coli and while other bacterial pathogens were not found, the intestinal protozoa giardia lamblia (13%), entamoeba histolytica (6%), entamoeba coli (6%), endolimax nana (6%), and enta ...1977351820
[acute intestinal amebiasis treated with aminosidine].a clinical-therapeutic assay carried out at the "william soler" pediatric teaching hospital in children admitted due to an acute diarrheic syndrome and treated with aminosidine sulfate is presented. histolytic ameba is still an element to be considered in the origin of gastroenteritis. the therapeutic action of aminosidine is evaluated.1977209805
intestinal and blood parasites in the north lore district, central sulawesi, indonesia.over 1,000 stool specimens from residents of the napu and besoa valleys, central sulawesi, indonesia were examined. schistosoma japonicum was detected in 31% of napu valley residents while in only 2% of the besoa valley residents. hookworm infections were the most frequently encountered helminth parasitisms in both valleys. other helminth parasites encountered were: ascaris lumbricoides, trichuris trichiura, enterobius vermicularis, strongyloides stercoralis, physaloptera sp., diphyllobothrium s ...1977335530
tinidazole and metronidazole in the treatment of intestinal amoebiasis.sixty adult patients with symptomatic intestinal amoebiasis and with entamoeba histolytica present in stools were allocated at random to treatment with tinidazole or metronidazole, both administered in a dose of 2 g once daily for 3 consecutive days. the treatment period was extended in patients with stools positive for entamoeba histolytica on the day following the last treatment day. fifty-six patients, 29 on tinidazole and 27 on metronidazole, completed the trial as per the protocol. twenty-e ...1977340131
surface properties related to concanavalin a-induced agglutination. a comparative study of several entamoeba strains.pathogenic strains of entamoeba histolytica are more easily agglutinated with concanavalin a (con a) than strains isolated from human asymptomatic carriers. all three pathogenic strains studied here were found to agglutinate with low concentrations of con a in contrast to various nonpathogenic axenic strains of amebas, characterized by their ability to grow at room temperature. our present observations suggest that the extreme susceptibility of pathogenic strains of e. histolytica to agglutinate ...1977233919
electron microscope studies of experimental entamoeba histolytica infection in the guinea pig. iii. histolysis of the cecum. 1977412297
radiology of invasive amebiasis of the colon.entamoeba histolytica is a protozoan that is endemic in various parts of the world, including some areas of the united states. it may live in the large bowel in its cyst form without harming the host (commensalism) or, for as yet poorly understood reasons, invade the tissues as a trophozoite producing invasive amebiasis of the colon. in a review of over 3,000 cases of invasive amebiasis, the clinico-pathologic forms of the disease were: ulcerative rectocolitis (95%), typhloappendicitis (3%), ame ...1977414558
the prevalence of human intestinal protozoa in ibadan, nigeria.this study shows that the two intestinal protozoa, giardia lamblia, balantidium coli in addition to entamoeba histolytica are prevalent in the ibadan population and are responsible for many of the non-bacterial diarrhoea seen in patients. a high seasonal prevalence of the intestinal protozoa in the dry months of the year was associated with the use of contaminated water. both the high infection rates recorded in adults and children under five years old, and the high frequency of association invo ...1977563477
[chemotherapeutically effective nitro compounds. 3rd communication: nitropyridines, nitroimidazopyridines and related compounds (author's transl)].new 2-nitropyridines and 3-nitropyridines, and 3-nitroimidazo-[1,2-a]-pyridines and related compounds (together 106) were synthesized and tested for their chemotherapeutic efficacy against trichomonads, amoebas and other organisms, such as eimeria tenella, bacteria, fungi, helminths. several 2-nitropyridines revelaed a detectable systemic effect against entamoeba histolytica (extraintestinal amoebiasis of the golden hamster) and also a weak activity against trichomonas fetus in the nmri-mouse. o ...1977576820
age and sex distribution of infections with entamoeba histolytica and giardia intestinalis in the lagos population.stool samples were collected from 2,099 persons and examined for parasites: 9.5 percent were infected with entamoeba histolytica, 7.9 percent were infected with giardia intestinalis and 15.5 percent were infected with iodamoeba butschlii. the infections with e. histolytica and i. butschlii occurred more frequently in females than in males and adults were also more frequently infected than children. infection with g. intestinalis, on the other hand, was more prevalent in males than in females and ...1977591169
parasites of man in remote areas of central and south sulawesi, indonesia.a biomedical survey was conducted in 10 villages in remote, high mountain valleys of central and south sulawesi, indonesia to learn whether oriental schistosomiasis was endemic and to determine the prevalences of other intestinal parasites, malaria and filariasis in those areas. although persons with oriental schistosomiasis were found in three villages of south sulawesi, follow-up inquiries revealed that these had recently migrated from a known schistosomiasis area in central sulawesi. other in ...1977607428
biomedical survey in north samar province, philippine islands.a biomedical survey was carried out in north samar province, philipines to update information on the prevalence of parasitic and other infectious diseases. a total of 1,394 stool specimens, 1,859 blood smears and 1,274 sera were collected from persons living in 8 barrios. stools were examined for intestinal parasites, bloods smears for malaria and filariasis and sera tested for antibodies to schistosoma japonicum, entamoeba histolytica, toxoplasma gondii, influenza a and b, and japanese encephal ...1977614707
[the laboratory diagnosis of amoebic infections in man (author's transl)].the rapid progress made in both theoretical and practical fields in laboratory medicine, in general, and in microbiological diagnostic procedures, in particular, have also led to a significant enlargement of, and improvement in laboratory diagnosis of amoebic infections in man. in all intestinal infections with entamoeba histolytica the demonstration of the parasite is absolutely essential, but is facilitated nowadays by the great improvement in technical conditions. immunodiagnostic methods hav ...1977842029
[toxoplasmosis. anatomo clinical characteristics and morphological indentification of the parasite using the silver-impregnation technic].the clinical and anatomicopathological characteristics of acute and chronic toxoplasmosis are described as they affect different structures and systems. the lesion to adrenal glands is compared to that seen in disseminated herpes simplex; however, the question remains as to why in both congenital infections, necrosis of adrenal glands appears without inflammatory reaction. the investigation of special techniques for localization and identification of toxoplasma gondii "groups" or cysts, leads to ...1977843413
plasmalemmal modifications of entamoeba histolytica in vivo.we used electron microscopy to study entamoeba histolytica trophyozoites in rectal and liver lesions. the amebal surface had bleblike structures. also noted were subplasmalemmal vacuoles and plasmalemmal extensions generally similar to the "surface lysosome" and "trigger" previously described. we found on serial sections that the plasmalemmal extensions were dendritic complexes enfolding the membrane of the subplasmalemmal vacuole and extending to contact host tissue. we postulate that membrane- ...1977845740
endemic amebiasis in an extended family.two cousins from a large spanish-american family were simultaneously diagnosed as having amebic liver abscesses. survey of 183 extended-family members revealed that 45.7% of 162 had a positive amebiasis indirect hemagglutination test and 12.6% of 111 had cysts or trophozoites of entamoeba histolytica demonstrated in a single stool examination. a total of five family members had had liver abscesses; two deaths had occurred. in a random sample survey of the remainder of the community, only one per ...1977889003
cellular immune responses to amoebic liver abcess in the guinea-pig.guinea-pigs infected in the liver with the biswas strain of entamoeba histolytica showed no dermal hypersensitivity but showed positive lymphocyte transformation and macrophage-migration inhibition. the time sequence showed an activated response at 4 days after infection, a full response at 8 days when the liver abscesses were resolving and a waning response at 12 days when the abscesses had healed.1977891028
[traveler's diarrhea].travellers' diarrhea afflicts up to 50 percent of tourists in certain geographic regions. it is a syndrome caused by a variety of pathogens, the most common of which is enterotoxigenic e. coli. other responsible pathogens include salmonellae, shigellae, entamoeba histolytica, yersinia enterocolitica, giardia lamblia and virus-like agents, seldom vibrios. symptoms persist for only a few days and are only serious in 1/5 of the cases.1977914154
parasitology survey in northern sumatra, indonesia.a parasitology survey was conducted in five villages in north sumatra, indonesia. a total of 3,207 blood smears, 2,066 stool specimens and 969 sera were examined. sixty (1.9%) inhabitants had malaria (plasmodium vivax 41, p. falciparum 19), and 20 had brugia malayi microfilaraemia. the most common intestinal helminths were trichuris trichiura (87%), ascaris lumbricoides (75%) and hookworm (58%). other helminths found in low numbers were enterobius vermicularis, strongyloides stercoralis, taenia ...1976950682
tinidazole: a review of its antiprotozoal activity and therapeutic efficacy.tinidazole, a synthetic imidazole derivative, has been used in the oral treatment of several protozoal infections - trichomoniasis, giardiasis and amoebiasis. among the protozoal organisms inhibited by tinidazole are trichomonas vaginalis, trichomonas foetus, and entamoeba histolytica. in vitro, tinidazole has been shown to possess antiprotozoal activity at least comparable to, and in some cases greater than, metronidazole. tinidazole also has activity against some gram-negative anaerobic bacill ...1976954609
therapeutic evaluation of oxantel pamoate (1, 4, 5, 6-tetrahydro-1-methyl-2-[trans-3-hydroxystyryl] pyrimidine pamoate) in severe trichuris trichiura infection.the efficacy of oxantel pamoate (1, 4, 5, 6-tetrahydro-2-[trans-3-hydroxystyryl]-1-methyl pyrimidine pamoate) was evaluated in 25 children with severe trichuris infection. the presence of chronic dysentery and sigmoidoscopic demonstration of whipworms in the intestinal mucosa were the criteria for inclusion in the trial. most of these patients had severe anemia, rectal prolapse, digital clubbing, hypoproteinemia, and growth retardation. there were a high incidence of concomitant parasitism with ...1976961973
observations on the intestinal protozoa infecting man in rhodesia.humans in rhodesia harbour a wide range of intestinal protozoa. of the species included, entamoeba histolytica, entamoeba coli and giardia lamblia have previously been recorded. other species which are either rarely reported or which have previously never been reported from this country, include trichomonas hominis, chilomastix mesnili, enteromonas hominis, retortamonas intestinalis, balantidum coli,entamoeba hartmanni,entamoeba histolytica laredo. endolimax nana, dientamoeba fragilis and isospo ...1976988643
action of antiamoebic drugs on ribonuclease and deoxyribonuclease activities of the caeca of rats infected with a virulent strain entamoeba histolytica. 1976992730
heavy trichuris infection and amoebic dysentery in orang asli children. a comparison of the two diseases.children with heavy trichuris infestation were compared with paediatric amoebic dysentery patients and normal children. heavy trichuris infestation was diagnosed by visualization of worms on anoscopy. patients with heavy trichuris infection had a longer duration of disease, more frequent hospitalization and a higher rate of rectal prolapse than did patients with amoebiasis. five trichuris children also had clubbing. trichuris patients had lower mean haematrocrits (27%) and serum albumin (3-3 gm% ...19761006759
parasitological survey in gorontalo north sulawesi, indonesia.a survey for blood and intestinal parasites was carried out in the municipality of gorontalo on the minahasa peninsula of north sulawesi. a total of 156 stool specimens were obtained from 83 males and 73 females. trichuris trichiura, ascaris lumbricoides, hookworm, unidentified dicrocoeliid-like ova and entamoeba coli, in that order, were the most common intestinal parasites detected. other intestinal parasites found less frequently were entamoeba histolytica, iodamoeba bütschlii, endolimax nan ...19761030844
intestinal and blood parasites of man in bireuen and takengon, aceh province, sumatra, indonesia.a survey for blood and intestinal parasites was carried out in aceh province of north sumatra, indonesia. a total of 348 stool specimens were obtained from 167 males and 181 females ranging in age from 6 months to 70 years. over 98% of the population sampled were found infected with at least one intestinal parasite. ascaris lumbricoides, trichuris trichiura, hookworm and entamoeba coli, in that order, were the most common parasites detected. other intestinal parasites found less frequently were ...19761030850
entamoeba histolytica in new zealand. 19761067494
electron microscope studies of experimental entamoeba histolytica infection in the guinea pig. ii. early cellular and vascular changes accompanying invasion of the lamina propria.early cellular and vascular changes in response to invasion of lamina propria by entamoeba histolytica were studied sequentially, at the ultrastructural level, in germfree guinea pigs inoculated intracecally with amebae and enteric flora derived from patients with acute amebic colitis. approximately one week post-inoculation the animals developed acute colitis with mucosal invasion by trophic amebae. although epithelial cells at the sites of amebic invasion showed progressive cytoplasmic changes ...1976816067
treatment of intestinal parasites in australian aboriginal children.five to nine-year-old aboriginal children on mitchell river community maintained a satisfactory growth rate in the presence of multiple infections with intestinal parasites. intensive treatment was successful in eliminating giardia lamblia, entamoeba histolytica, and strongyloides stercoralis infections, but reinfection with g. lamblia was rapid. treatment failed to produce any growth spurt in the group. this may have been due to the rapidity of reinfection, but raises the question of whether in ...19761263912
parasitic infections in humans in west kalimantan (borneo), indonesia.a survey was carried out among inhabitants of eight villages in west kalimantan province (borneo), whereby blood smears were examined for malaria, stools examined for intestinal parasites and sera tested by the indirect hemagglutination test for antibodies to entamoeba histolytica and toxoplasma gondii. the prevalence of malaria among 3017 people examined was 5.6% (plasmodium vivax 2.8%, plasmodium falciparum 2.8%). brugia malayi microfilariae were found in 3.6% and wuchereria bancrofti in 0.3%. ...1976788263
algorithms in the diagnosis and management of exotic diseases. xvii. amebiasis. 197612237
[amoebas with special reference to entaboeba histolytica. symptomatology, diagnosis and results of a survey conducted in huambo, angola]. 1976205139
[intraperitoneal rupture of an amebic liver abscess. apropos of a clinical case]. 1976205140
iron--sulfur proteins of entamoeba histolytica. 19763636
interrelationship of ph and oxidation-reduction potential on growth of axenic entamoeba histolytica and the influence of ph on amoebicidal activity of drugs. 19765371
membrane structure of entamoeba histolytica: fine structure of freeze-fractured membranes. 1976175169
[cutaneous amebiases (stimulating pyoderma gangrenosum in ulcerative colitis)]. 1976175301
nicotinamide nucleotide transhydrogenase in entamoeba histolytica, a protozoan lacking mitochondria. 1976175989
orphan airlift. enteric pathogens isolated from vietnamese children immigrating to the united states.isolation studies for bacterial and parasitic agents were carried out on stool specimens from vietnamese infants at the time of their mass airlift to the united states. one or more bacterial pathogens were found in 49% of the 367 stool specimens cultured. the isolates included enteropathogenic escherichia coli (161), shigella (16), salmonella (15), but no salmonella typhi or vibrio cholerae. parasites identified in 88 stool specimens included giardia lamblia (10), ascaris lumbricoides (7), and e ...1976176481
survival of monoxenically (crithidia sp.) and axenically grown entamoeba histolytica cultures after storage in liquid nitrogen. 1976177374
the value of amoebic serology in an area of low endemicity.one hundred sera from army patients who had had amoebiasis in the past and 113 sera from coloured immigrants attending a venereal diseases clinic were examined by four serological techniques. the indirect haemagglutination and the latex agglutination tests showed almost complete correlation; they are useful epidemiological tools but too sensitive and the antibodies on which they depend are too persistent for clinical use. the indirect fluorescent antibody test is a good clinical screening test, ...1976178079
in vitro sensitivity of entamoeba histolytica to furazolidone and iodochlorhydroxyquin, separate and combined.entamoeba histolytica trophozoites isolated in robinson's medium from faeces containing cysts, transported from india, have been tested in vitro against the drugs furazolidone, iodochlorhydroxyquin, and both drugs combined as dependal. results show the levels at which drug action is significant and that interaction between the drugs occurs at two concentrations.1976178080
the rhabdoviruses of entamoeba histolytica and entamoeba invadens.rhabdoviruses have been described in plants, arthropods and vertebrates including man. members of the group are of agricultural, veterinary and medical importance. the presence of a rhabdovirus in entamoeba histolytica and entamoeba invadens is the first record of their existence within protozoa. the morphology of this virus is described and its significance discussed, in relation to a possible lysogenic state and pathogenecity of entamoeba species.1976178279
6-phosphofructokinase (pyrophosphate). properties of the enzyme from entamoeba histolytica and its reaction mechanism.the inorganic pyrophosphate-requiring 6-phosphofructokinase of entamoeba histolytica has been further investigated. the molecular weight of the enzyme is approximately 83,000 and its isoelectric point occurs at ph 5.8 to 6.0. the divalent cation requirement for reaction was explored. in the direction of fructose 6-phosphate formation half-maximal rate required 500 mum magnesium ion; in the direction of fructose bisphosphate formation 8 mum magnesium ion sufficed. atp, ppi, polyphosphate, acetyl ...1976178659
[immunofluorescence technic in the diagnosis of amebiasis]. 1976192988
[study of the antiprotozoal activity of compounds of the series of diphenyl ethers and certain nitrostyrols]. 1976192989
comparison of some methods for the detection of antigen-antibody reactions in amoebiasis.the indirect hemagglutination test (iha) and counterimmuno-electrophoresis (cie) were used to test for antibodies to entamoeba histolytica in human sera using antigens from axenic cultures of the hk9 strain. correlation between the test was excellent with most sera from patients with amoebiasis demonstrating precipitin lines by cie at iha titers considered diagnostically positive, larger than or equal to 1:128. precipitin reactions with positive sera were also compared by cie, immunoelectrophore ...1976193204
[fluorescent antibody technic as a diagnostic test in amebiasis]. 1976191740
[incidence of parasitic infestation by entamoeba histolytica in population samples in zaire evaluated in the laboratory by parasitologic and immunofluorescent methods]. 1976189706
selective ability of entomoeba histolytica to haemolyse red blood cells--a preliminary communication. 1976190167
search for laredo type amoebae among entamoeba histolytica. 1976190168
amoebiasis on easter island. 1976190741
freeze-etching observations of trophozoites of pathogenic entamoeba histolytica.pathogenic entamoeba histolytica trophozoites were studied by the freeze-etching (fe) technique of electron microscopy. surface replicas of intact cell membranes were highly convoluted with numerous invaginations, evaginations, and undulations. sperical depressions and elevations varying from 0.5 mu to 1.0 mu in diameter were commonly present on the external cell membrane and appeared to represent an extracellular secretory mechanism of trophozoites. cleaved surfaces of amebae exhibited a granul ...1976176837
[non-mitochondrial dna in cytoplasm]. 1976179237
protozoal viruses. 1976179308
laboratory investigation of diarrhea in travelers to mexico: evaluation of methods for detecting enterotoxigenic echerichia coli.a laboratory investigation was conducted on cultures collected from travelers before, during, and after a trip to mexico to characterize the etiology of traveler's diarrhea. four laboratory methods for detecting enterotoxigenicity of escherichia coli were evaluated: the infant mouse assay, the chinese hamster ovary (cho) cell assay, the y1 adrenal cell assay, and the rabbit ileal loop. although a number of common enteric pathogens were identified as a cause of traveler's diarrhea, including six ...1976180047
[raynaud syndrome of unusual etiology]. 1976180472
endemic amebiasis in an arkansas community.parasitologic, serologic, and epidemiologic studies were done during 1967 in calion, arkansas (population 544). infection with entamoeba histolytica was found to be endemic but was segregated along racial lines. twenty-two (9.9%) black compared with only one (0.6%) white had e. histolytica demonstrated in one stool examination; only two blacks had symptoms suggestive of amebiasis. no positive amebiasis indirect hemaggulination titers were found in 135 white residents. in contrast, 41 (17.9%) bla ...1976180800
amebiasis of clitoris mimicking carcinoma. 1976181603
search for potential amoebicides. part v. n-substituted 2-nitro-4,5-dimethoxybenzamides and anils of 2-amino-3-methoxy and 2-amino-4,5-dimethoxybenzoic acids.the authors in all have synthesised 28 new n-substituted 2-nitro, 4,5-dimethoxy-benzamides, and anils of 2-amino-3-methoxy and 2-amino-4,5-dimethoxybenzoic acids with a view to obtain potent amoebicides. their work is based on the observation that a large number of dimethoxyphenyl substituted derivatives occupy an important place as antiamobic agents. fourteen belonging to different series subjected to in vitro screening for amoebicidal activity against e. histolytica failed to show any signific ...1976181737
incorporation of purines and pyrimidines in axenically grown entamoeba histolytica. 1976182949
double-blind test of metronidazole and tinidazole in the treatment of asymptomatic entamoeba histolytica and entamoeba hartmanni carriers.one hundred and fifteen persons with asymptomatic entamoeba histolytica or e. hartmanni infection, or both, were given metronidazole (750 mg three times daily for 5 days), tinidazole (1 g twice daily on 2 consecutive days), or a starch placebo. three post-treatment stools were examined in the 2 weeks following initiation of treatment. cysts of e. histolytica reappeared in the stools of 37% of 30 given metronidazole, 62% of 34 given tinidazole, and 70% of 31 given placebo. cysts of e. hartmanni r ...1976183554
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