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ultrastructure of hamster kidney cell culture infected with herpesvirus.hamster kidney cell culture was found susceptible to infection and replication of herpesvirus of turkey (hvt) as evidenced by cytopathic effect, induction of hvt-specific, complement-fixing antigen, and demonstration of virus particles by electron microscopy. viral structures at different developmental stages were observed. several infected cells showed a lamellar inclusion body possibly continuous with the endoplasmic reticulum. the function of these lamellar bodies is not known.19744842129
the comparative influence of passive (maternal) antibodies in early exposure to jm virus of progeny chicks of dams vaccinated with jm-v leukosis strain and herpesvirus of turkey (hvt). 19744854686
use of japanese quail embryo fibroblast cells for propagation and assay of turkey herpesvirus fc-126.japanese quail (coturnix coturnix japonica) fibroblast cell culture monolayers were found to provide a very satisfactory system in which to propagate and assay turkey herpesvirus fc-126, which is used for production of marek's disease vaccine. japanese quail cells were more sensitive than duck cells and of approximately equal sensitivity to chicken cells. foci of infection developed rapidly and uniformly, were of larger size, and were more easily discernible in quail cells than in chicken cells.19744855648
properties of the common antigen associated with marek's disease herpesvirus and turkey herpesvirus infections. 19744363692
antibody response of susceptible and resistant chickens (type-ii leukosis) infected with jm and jm-v leukosis strains and herpesvirus of turkeys (hvt). 19744368422
marek's disease virus and the herpesvirus of turkeys. 19744371178
vaccination of chickens against marek's disease with cell-free herpesvirus of turkeys vaccine. 19744429246
electron microscopic autoradiography in the development of herpesvirus of turkey. 19744441257
[electron microscopic study of the genesis, fine structure and relationship between virus and host cell of a turkey herpesvirus in cell culture]. 19744460929
quantitative assay of turkey herpesvirus in vaccines against marek's disease of chickens. 19744462110
vaccination against marek's disease with the turkey herpesvirus vaccine. 19744462113
[studies on herpesvirus of turkeys. i. isolation of herpesvirus from turkeys and its virological characteristics (author's transl)]. 19744474560
[effect of homologous maternal antibodies on the vaccination with herpesvirus of turkeys (hvt)]. 19744598094
transient infectivity and heterokaryon formation in hamster cell cultures inoculated with cell-associated stocks of marek's disease virus and herpesvirus of turkeys. 19744612166
lyophilized turkey herpesvirus (hvt): stability of vaccine and minimum protective dose.the research reported showed that: the stability of cell-free hvt vaccine, lyophilized and sealed under vacuum, is very high: after one year at 4 degrees -6 degrees c and after 10 days at 37 degrees c the titre decreased only about 0.4 log(10)', the stability of the vaccine, when reconstituted for use in the diluent (sucrose-phosphate buffer), is high (80%) for at least 2 hours; the degree of protection, found in 3 tests, was about 90% with an inoculum of 20 to 100 pfu, and the pd50 was 4.9 pfu ...197418777253
simultaneous vaccination of day-old chickens against newcastle and marek's diseases.commercial day-old chicks vaccinated against marek's disease (md) with turkey herpesvirus (hvt) were tested for their ability to respond to a live newcastle disease vaccine (ndv) - la sota strain - administered by different routes. simultaneous vaccination of day-old birds with hvt and ndv did not affect the immune response to ndv nor the viraemia induced by hvt vaccination. md and nd vaccinations performed together, the first by the intramuscular route and the second by beak dipping, gave a val ...197418777255
vaccination against marek's disease: possible causes of failure of herpesvirus of turkeys (strain fc126) to protect chickens against marek's disease. 19734350544
horizontal transmission of turkey herpesvirus to chickens. 2. some factors affecting transmission. 19734350858
viraemia and antibody development in chicks following the administration of turkey herpesvirus. 19734352992
stability of the apathogenic nononcogenic character of a turkey herpesvirus used to immunise fowls against marek's disease. 19734718146
efficacy of cellfree and cell-associated herpesvirus of turkeys vaccines in progeny from vaccinated parental flocks. 19734720673
plaque assay of turkey herpesvirus and attenuated marek's disease virus. 19734722361
replication of herpesvirus of turkeys in hamster urogenital cell cultures. 19734734889
neutralization studies with marek's disease virus and turkey herpesvirus.use of marek's disease virus (mdv) in a neutralization test presents several problems, which are described, making this potentially useful test difficult. to obviate these difficulties, a plaque reduction test has been designed based on cross-neutralization of turkey herpesvirus (hvt) by serum-neutralizing mdv. the technique for such a neutralization test is outlined. kinetics of development of neutralizing antibodies in chickens inoculated with hvt and mdv are described. the neutralization test ...19734767297
efficacy of turkey herpesvirus vaccine against marek's disease in broilers. 19734773339
dose effect of herpesvirus of turkeys on protection of chickens from marek's disease. 19734792400
immunologic relationship between jm and jmv leukosis strains and herpesvirus of turkeys. 19734795894
marek's disease vaccine: prophylactic efficacy of a lyophilized turkey herpesvirus of chick cell-culture origin. 19734633273
susceptibility of guinea pig cell cultures to infection with cell-bound and cell-free herpesvirus of turkeys.cell-bound and cell-free herpesvirus of turkeys infected and replicated in guinea pig cell cultures as evidenced by cytopathic effects, intranuclear inclusions, and the presence of herpesvirus particles as seen by electron microscopy were studied in this investigation. further evidence for the replication of herpesvirus of turkeys in cell cultures was determined by serum neutralization, complement fixation, and the fluorescent antibody tests.19734581013
effect of antibiotics on turkey herpesvirus vaccine. 19734122718
serological relationships among herpesviruses: cross-reaction between marek's disease virus and pseudorabies virus as detected by immunogluorescence.marek's disease virus (mdv) and pseudorabies virus (prv) cross-reacted by fluorescent antibody test but not by gel diffusion, virus neutralization, or cross-protection tests. herpesvirus of turkeys cross-reacted with mdv but not with prv. other herpesviruses tested did not have cross-reactions.19724117951
course of infection in tissues of susceptible chickens after exposure to strains of marek's disease virus and turkey herpesvirus. 19724650200
long-term experiences with the herpesvirus of turkeys (hvt) as a vaccine against marek's disease. 19724660528
immunization of one-day-old chicks against marek's disease with turkey herpesvirus. 19724660529
vaccination experiments against marek's disease by application of an attenuated marek herpesvirus and a turkey herpesvirus. 19724660530
growth characteristics of a herpesvirus of turkeys.the herpesvirus of turkeys remains associated with cells attached to the culture vessel throughout its growth cycle. the level of infectious centers is essentially constant between 24 and 48 hr when the culture medium is unchanged. thereafter, the number of infectious centers decreases. the cessation of virus synthesis is not due to insufficient numbers of uninfected cells or interferon production. herpesvirus of turkeys does not replicate at 22 c and is similar to other herpesviruses in its sen ...19724675446
[isolation of turkey herpesvirus in france]. 19724676686
in vitro methods for assay of turkey herpesvirus. 19725026286
performance response of a leghorn-type layer flock to turkey herpesvirus vaccine. 19725026287
viral interference of types 1 and 2 plaque-producing agents derived from cal-1 strain of marek's disease herpesvirus and turkey herpesvirus. 19725030950
turkey herpesvirus: lack of oncogenicity for turkeys. 19725038659
in vitro assay of cell-free turkey herpesvirus. 19725062812
induction of deoxyribonucleic acid synthesis and the oncogenicity of marek's disease virus.leukocytes recovered from birds inoculated with an oncogenic strain of marek's disease virus synthesized deoxyribonucleic acid in vitro at a rate 7.9 times that of leukocytes from normal birds or birds inoculated with the nononcogenic herpesvirus of turkeys. a close relationship was observed between the level of in vitro deoxyribonucleic acid synthesis and in vivo tumor formation.19725073927
inoculation of one-day-old chicks with different strains of turkey herpesvirus. i. serological studies. 19725079871
inoculation of one-day-old chicks with different strains of turkey herpesvirus. ii. virus replication in tissues of inoculated animals. 19725079877
vaccination against marek's disease with cell-free turkey herpesvirus: interference by maternal antibody. 19725079883
vaccination with lyophilized turkey herpesvirus (hvt): minimum infective and protective doses. 19724623703
studies on the in vivo replication of turkey herpesvirus. 19724343472
lack of pathogenicity of marek's disease virus and herpesvirus of turkeys in marmoset monkeys. 19724343475
the fine structure of marek's disease virus and herpesvirus of turkey in cell culture. 19724347435
cell surface antigen on quail cells infected with herpesvirus of turkey or marek's disease virus. 19724349460
the in vitro assay of the herpesvirus of turkeys. 19724349817
[titration of turkey herpesvirus in marek's disease vaccines]. 19724562834
a multilayer cell-culture technique to improve yields of a herpesvirus of turkeys. 19724565460
effects of passive antibody on early pathogenesis of marek's disease.the effects of passive marek's disease virus (mdv) antibody were characterized in three experiments in which 1- or 2-day-old pdrc chickens were inoculated with cell-associated mdv. antibody acquired naturally from the dam, or injected prior to, or at the time of, virus inoculation, failed to prevent infection, but the incidence and severity of the acute necrotizing disease were reduced. also, the number of tissues with viral antigen (fluorescent antibody test) and the amount of antigen in positi ...19724569917
production of interferon by the cal-1 and turkey herpesvirus strains associated with marek's disease. 19724335398
production of circulating and cell-bound interferon in chickens by type 1 and type 2 plaque-producing agents of the cal-1 strain of marek's disease herpesvirus and herpesvirus of turkeys. 19724335399
preliminary observations on egg transmission of turkey herpesvirus (hvt) in turkeys. 19724337315
experimental infection of turkeys and chickens with a herpesvirus of turkeys (hvt). 19724337317
long-term field trials with the herpesvirus of turkeys vaccine against marek's disease. 19724337318
susceptibility of mammalian (hamster) cell culture to infection with herpesvirus of turkeys.herpesvirus of turkeys (hvt) infected and replicated in hamster kidney cells as evidenced by cytopathic effects, intranuclear inclusions, and by the presence of herpesvirus particles as seen by electron microscopy. additional evidence for the presence of hvt in cell cultures was determined by the serum neutralization, complement fixation, and the fluorescent-antibody tests.19724341969
epidemiology of a herpesvirus of turkeys: possible sources and spread of infection in turkey flocks.parameters of turkey herpesvirus (hvt) infection were followed sequentially from hatching through 20 weeks in two commercial turkey flocks. maternal antibody was uniformly present at hatching but decreased below detectable levels by the 3rd week. virus was first isolated at the 5th and 6th weeks and thereafter spread rapidly within the flocks. development of active antibody followed that of viremia by 1 week. both virus and antibody were present in virtually all turkeys after the 7th or 10th wee ...19714343407
ultrastructural studies of a herpesvirus of turkeys antigenically related to marek's disease virus. 19714322626
isolation of turkey herpesvirus in cell culture. 19714325202
effect of vaccination with herpesvirus of turkeys (hvt) on horizontal spread of marek's disease herpesvirus. 19714325826
horizontal transmission of turkey herpesvirus to chickens. 1. preliminary observation. 19714328146
marek's disease: resistance of turkey herpesvirus-infected chicks against lethal jm-v agent. 19714329922
interferon production and host resistance to type ii avian (marek's) leukosis virus (jm strain).interferon production in both susceptible s- and resistant k-line chickens infected with type ii leukosis virus of jm strain and turkey herpesvirus was studied. the resistant line of chickens produced higher levels of interferon than did the susceptible with jm virus infection during the experimental period. when both susceptible s-and resistant k-line chicks were vaccinated with turkey herpesvirus, the interferon production was quantitatively similar in the two lines.19714332041
the temporal relationship between vaccination with the herpesvirus of turkeys and challenge with virulent marek's disease virus. 19714334075
responses of cell cultures from various avian species to marek's disease virus and herpesvirus of turkeys. 19714107762
pathogenicity and antigenicity of clones from strains of marek's disease virus and the herpesvirus of turkeys.virus was extracted by filtration from chicken embryo fibroblast cultures infected with the jm, high passage jm(jmhp), ga, and rpl39 strains of marek's disease virus (mdv) and from the herpesvirus of turkeys (hvt) and purified by cloning. the plaques produced by clones of hvt, jmhp, and other mdv strains differed in morphology from one another. clones of mdv varied greatly in pathogenicity for chickens, but jmhp and hvt were nonpathogenic. two pathogenic clones of jm virus and a clone of jmhp vi ...197116557968
lyophilization of cell-free marek's disease herpesvirus and a herpesvirus from turkeys.cell extracts of the jm and ga strains of marek's disease herpesvirus and the fc 126 strain of turkey herpesvirus were lyophilized with various stabilizers. much higher virus titers were obtained with stabilizer than without stabilizer. titers increased even further in the case of the marek's disease virus strains by the addition of a chelating agent, disodium ethylenediaminetetraacetate.19704320863
protection against marek's disease by vaccination with a herpesvirus of turkeys. 19704913403
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