Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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molecular phylogeny of hypoxylon and closely related genera. | phylogenetic relationships were inferred among several xylariaceous genera with nodulisporium or nodulisporium-like anamorphs based on the analyses of beta-tubulin and alpha-actin sequences. one hundred nine cultures and three specimens of 83 representatives of these four genera were included in the study. biscogniauxia taxa formed a well supported clade that was basal to the other taxa, while taxa of hypoxylon and daldinia comprised a large monophyletic group that contained two subclades. the f ... | 2005 | 16457354 |
treatment of tinea capitis caused by microsporum ferrugineum with itraconazole. | a prospective, non-randomized, open clinical trial was conducted to determine the efficacy of itraconazole for treatment of microsporum ferrugineum tinea capitis. itraconazole capsules were given every day in continuous group and every day for 1 week on and 3-week off in pulse therapy group. concomitant topical therapy with 2% ketoconazole shampoo was used daily. clinical evaluation consisted of assessing the degree of hair loss, scaling, erythema, pustule, and crust. in both groups, the treatme ... | 2005 | 16856430 |
fungal infections of the skin: infection process and antimycotic therapy. | dermatomycoses are among the most widespread and common superficial and cutaneous fungal infections in humans. these typically nonfatal conditions are difficult to treat, especially infections of the nail. dermatomycoses are caused by filamentous fungi such as trichophyton, microsporum or epidermophyton species. these filamentous fungi have a high affinity for keratin, an important component of hair, skin and nails, which are the primary areas of infection by dermatophytes. the antifungal agents ... | 2005 | 16375669 |
antifungal activity of fluid extract and essential oil from anise fruits (pimpinella anisum l., apiaceae). | antifungal activities of fluid extract and essential oil obtained from anise fruits pimpinella anisum l. (apiaceae) were tested in vitro on clinical isolates of seven species of yeasts and four species of dermatophytes. diffusion method with cylinders and the broth dilution method were used for antifungal activity testing. anise fluid extract showed antimycotic activity against candida albicans, c. parapsilosis, c. tropicalis, c. pseudotropicalis and c. krusei with mic values between 17 and 20% ... | 2005 | 16375827 |
antimicrobial activity of flavonoids from pelargonium radula (cav.) l'hérit. | flavonoids from pelargonium radula (cav.) l'hérit were purified by column chromatography. two fractions were obtained: f1 (main flavonoid isoquercitrin) and f2 (main flavonoid rutin). in vitro antimicrobial activity of f1 and f2 were tested against eleven species of bacteria and eleven species of fungi. both fractions demonstrated strong inhibitory activity against staphylococcus aureus, proteus rettgeri, candida tropicalis and microsporum gypseum. staphylococcus sp. (coagulase-negative) and can ... | 2005 | 16375833 |
tinea faciei in a goat handler due to microsporum canis. | 2005 | 16309360 | |
reproducible genetic transformation system for two dermatophytes, microsporum canis and trichophyton mentagrophytes. | a reproducible genetic transformation system was developed for two major dermatophytes, microsporum canis and trichophyton mentagrophytes. two circular transformation vectors carrying either the bacterial hygromycin b phosphotransferase gene (hph) or both the hph and green fluorescent protein (egfp) genes under the control of a promoter sequence from cochlibolus heterostrophus were introduced independently into the protoplasts by a polyethylene glycol (peg)-mediated method. polymerase chain reac ... | 2005 | 16320496 |
clinical diagnosis of common scalp disorders. | scalp skin is unique on the body due to the density of hair follicles and high rate of sebum production. these features make it susceptible to superficial mycotic conditions (dandruff, seborrheic dermatitis, and tinea capitis), parasitic infestation (pediculosis capitis), and inflammatory conditions (psoriasis). because these scalp conditions share similar clinical manifestations of scaling, inflammation, hair loss, and pruritus, differential diagnosis is critically important. diagnostic techniq ... | 2005 | 16382661 |
tinea faciei in an infant caused by microsporum gypseum simulating a dry impetigo. | we report a 14-month-old white boy who was referred to our dermatology unit for evaluation of a skin eruption on his nose. the initial examination led us to the clinical diagnosis of impetigo. the mycologic studies found an uncommon dermatophyte agent, microsporum gypseum. the main differential diagnosis of tinea faciei is discussed. | 2005 | 16354256 |
is itraconazole the treatment of choice in microsporum canis tinea capitis? | mycotic scalp infection caused by microsporum canis is the most dominant cause of tinea capitis in greece. griseofulvin has been the gold standard for the treatment of tinea capitis, but it is unavailable in our country. in this study, we evaluated 111 children with m. canis tinea capitis that were treated with itraconazole. eighty-one of them were treated with itraconazole capsule pulse therapy (group a) and 30 (group b) were treated with oral suspension administered in continuous regimen. twen ... | 2005 | 16444907 |
importance of mycological confirmation of clinically suspected cases of tinea corporis, tinea pedis and tinea cruris. | tinea corporis, tinea cruris, and tinea pedis are of the most prevalent dermatophytoses. several conditions that mimic dermatophytoses and atypical and steroid modified forms of the disease usually present difficulties in diagnosis. hence, the present investigation aimed at studying these conditions on mycological basis. the study included 163 cases clinically diagnosed as having tinea corporis, tinea pedis or tinea cruris. specimens were taken by skin scraping. samples were cultured on sabourau ... | 2004 | 16916049 |
inhibitory effect of the plant boerhavia diffusa l. against the dermatophytic fungus microsporum fulvum. | antifungal activity (reduction in colony diameter) of various extracts (pt. ether, chloroform, ethyl acetate, ethyl alcohol and aqueous) of aerial and root parts of boerhavia diffusa (nictaginaceae) was screened against dermatophytic fungi microsporum fulvum. statistically significant increase has been recorded in the % inhibition of the target fungal species with increasing test concentrations (1000-5000 ppm) of chloroform, ethyl acetate and ethyl alcohol extracts of the root. the maximum % inh ... | 2004 | 15847339 |
evaluation of microsporum canis in different methods of storage. | the main objective of this investigation was to evaluate different methods of storage for microsporum canis based on materials and equipment that are readily available in developing countries. we tested 32 strains of m. canis at - 20 degrees c in potato dextrose agar (pda) in its plain condition, or amended with 10% dimethyl sulfoxide or with 10% glycerol. in addition, we tested 25 degrees c storage of isolates in plain saline (0.9% nacl) and in saline covered with a mineral-oil layer. after 9 m ... | 2004 | 15682637 |
[dermatophyte species isolated from patients prediagnosed as onychomycosis and the value of fungal culture]. | in this study, the clinical specimens taken from 390 patients who were prediagnosed as onychomycosis have been investigated by direct microscopy and culture methods, in the mycology unit of central laboratory of kocaeli university medical faculty. twenty-one (41.2%) of the 51 microscopically positive samples revealed positive cultures for dermatophytes, whereas 32 (9.4%) samples were culture positive among the 399 samples which were microscopically negative. the most frequently isolated dermatop ... | 2004 | 15700670 |
[investigation of the inter-observer agreement rates for morphometric evaluation of the growth of microsporum canis colonies]. | morphometry is a newly applied method for investigation of the in-vitro growth dynamics of dermatophyte colonies. this study was undertaken to evaluate the correlation and agreement rates between the morphometric data obtained by different observers. for this purpose, five different microsporum canis growth data were evaluated by six observers. the results of the study suggested that the agreement rates among the data obtained by different observers were low (r1 = -5.3509), while the results obt ... | 2004 | 15700671 |
tinea capitis in infants in their first year of life. | tinea capitis is the most common type of dermatophytosis in children, but is uncommon in the first year of life. | 2004 | 15491432 |
stereoselective synthesis and antifungal activity of (z)-trans-3-azolyl-2-methylchromanone oxime ethers. | a series of (z)-trans-3-azolyl-2-methylchromanone oxime ethers were stereoselectively synthesized and tested for in vitro antifungal activity. many of these derivatives exhibit high activity against candida albicans, saccharomyces cerevisiae, aspergillus niger, and microsporum gypseum. | 2004 | 15498664 |
tinea capitis caused by microsporum canis treated with terbinafine. | tinea capitis is a disease found throughout the world. it frequently affects children and only rarely adults, usually post-menopausal women. numerous dermatophytes of the genus microsporum and tricophyton can cause tinea capitis and griseofulvin is still today the treatment of choice. to study the effectiveness and tolerability of terbinafine treatment in tinea capitis caused by microsporum canis we treated 26 patients - 22 children and four women - for a period of 12 weeks. dosage adopted was 6 ... | 2004 | 15504128 |
bizarre annular lesion emerging as tinea incognito. | tinea incognito has first been described in 1968. the term describes a tinea infection whose clinical morphology has been modified by the application of topical corticosteroids. the clinical manifestation can masquerade a number of other dermatoses and leads to misdiagnosis of annular eruptions. we describe a patient who showed a bizarre appearance of annular, inflammatory skin lesions at the umbilical region. mycological culture yielded microsporum canis. | 2004 | 15504132 |
griseofulvin versus terbinafine in the treatment of tinea capitis: a meta-analysis of randomized, clinical trials. | tinea capitis, a common pediatric infection in the united states, is caused mainly by trichophyton species and affects many urban children. although the current treatment of choice is oral griseofulvin, terbinafine has been shown to be variably effective in several comparative, randomized trials. the purpose of this study was to perform a meta-analysis of randomized, clinical trials comparing the efficacies of oral terbinafine and oral griseofulvin for the treatment of childhood tinea capitis. | 2004 | 15520113 |
diversity of keratinophilic mycoflora in the soil of agra (india). | diversity of keratinophilic mycoflora in the soil of agra was under observation for 1 year (july 2001-june 2002) and isolation of keratinophilic fungi was followed by the hair-baiting method. the frequency of occurrence of keratinophilic fungi in 284 soil samples collected from various hospitals, cattle yards, poultry farms, crop fields and playgrounds was determined, 204 samples (72%) having been found to be positive. a total of 33 species classified into 11 genera (acremonium, aspergillus, chr ... | 2004 | 15530009 |
myths and misconceptions: not all that glitters under the watch is gold (nickel) dermatitis. | 2004 | 15538087 | |
treatment of microsporum spp. tinea capitis with pulsed oral terbinafine. | oral terbinafine is widely used in the treatment of superficial dermatomycoses as well as subcutaneous and systemic mycoses. it is also useful in treating tinea capitis, although for microsporum canis and some ectothrix organisms, the effectiveness of the drug may be less than for some endothrix infections. in this study, we undertook a double-blind randomized trial comparing standard and double doses of terbinafine given in a pulsed protocol (1 week on, 3 weeks off) in treating microsporum spp. ... | 2004 | 15115516 |
[chitin synthase (chs) gene analysis of dermatophytes]. | about 620-bp genomic dna fragments of chs1 genes were amplified from 13 species of dermatophytes by polymerase chain reaction (pcr) and sequenced. the phylogenetic analysis of chs1 gene fragments of these dermatophyte species revealed that 3 genera of epidermophyton, microsporum and trichophyton were genetically different from each other. the molecular analysis of chs1 genes will provide useful information for the identification of dermatophytes. the species-specific primers were designed from t ... | 2004 | 15118658 |
[superficial infections caused by microsporum canis in humans and animals]. | dermatophytic infections caused by m. canis in humans and animals have a world wide distribution and they are zoonotic. the objective in this work was to know the frequency of m. canis infections in humans and pets. we studied our cases from january 1994 to december 2002. the human samples were obtained from a dermatological department in a general hospital and we registered the next data: age, sex, job, and affected area. the animal samples were obtained from a mycological veterinary laboratory ... | 2004 | 15458362 |
[epidemiology of tinea capitis in abidjan, cote d'ivoire]. | tinea capitis is a dermatosis of the scalp due to dermatophytes that can cause hair loss. it remains a significant endemic problem mainly in school children in tropical regions. the purpose of this case-control study carried out in the dermatology center of treichville hospital was to identify risk factors for tinea capitis in abidjan, cote d'ivoire. a total of 80 cases were recruited on the basis of clinical findings showing one or several plaques showing desquamation or parakeratosis suggestiv ... | 2004 | 15460148 |
antimicrobial and free radical scavenging activity of gentianella nitida. | the antimicrobial and free radical scavenging activity of the ethanol extract and fractions of gentianella nitida have been assessed. the most susceptible microorganisms were candida albicans, trichophyton mentagrophytes and microsporum gypseum. the antifungal activity was concentrated in the 90% methanol and nonsoluble fractions, while the radical scavenging activity was stronger in the ethyl acetate and nonsoluble fractions. | 2004 | 15567257 |
efficacy of pre-treatment with lufenuron for the prevention of microsporum canis infection in a feline direct topical challenge model. | oral lufenuron is reportedly an effective treatment for some cats with dermatophytosis. the purpose of this study was to determine if lufenuron, when used as a pre-treatment prior to challenge exposure, would be protective against the development of infection after the direct topical application of fungal macrocondia (microsporum canis spores). three groups (n = 6/group) of juvenile cats were treated with either monthly oral lufenuron (30 or 133 mg/kg) or placebo. after 2 months of treatment, ki ... | 2004 | 15585010 |
in vitro evaluation of griseofulvin against clinical isolates of dermatophytes from isfahan. | fifty dermatophyte isolates, recently obtained from clinical materials, belonging to trichophyton mentagrophytes, t. verrucosum, microsporum canis and epidermophyton floccosum were examined for their susceptibility to griseofulvin. the minimum inhibitory concentration (mic) values were obtained using the modified microdilution method. all 100% tested isolates had mic geometric mean at a concentration between 0.43 and 0.95 microg ml(-1) the mic(90)s and mic(50)s were 8 microg ml(-1) and <0.25-1 m ... | 2004 | 15601457 |
the epidemiology of canine and feline dermatophytoses in southern italy. | a total of 424 animals (268 dogs and 156 cats) with skin lesions (alopecia and peripheral scaling) were examined from january 1999 to december 2002. of the 424 samples examined, 99 (23.3%) yielded a positive culture and, in particular, 20.5% of the dog samples and 28.2% of the cat samples. microsporum canis was the most common dermatophyte isolated from dogs and cats (77.7%), followed by geophilic dermatophyte species (m. gypseum, trichophyton terrestre). young dogs and cats, especially those yo ... | 2004 | 15601458 |
evaluation of inhibitory effect of the plant phyllanthus amarus against dermatophytic fungi microsporum gypseum. | the antifungal activity of various solvent extracts (such as ether, chloroform, ethyl acetate and ethyl alcohol) of the plant phyllanthus amarus against dermatophytic fungi microsporum gypseum was observed. | 2004 | 15602834 |
keratinophilic fungi of poultry farm and feather dumping soil in tamil nadu, india. | soils of 10 poultry farms from namakkal and 12 feather dumping sites from chennai were studied for the presence of keratinophilic fungi. a total of 34 species belonging to 19 genera and one non-sporulating fungus were recovered. sixteen species of fungi and one non-sporulating fungi were common to both sites, eight species were specific to namakkal and nine species were specific to chennai. dermatophytes and closely related fungi were represented by six species belonging to five genera. fungal s ... | 2004 | 15645172 |
isatin-derived antibacterial and antifungal compounds and their transition metal complexes. | a series of isatins incorporating thiazole, thiadiazole, benzothiazole and p-toluene sulfonyl hydrazide moieties, along with their cobalt(ii), copper(ii), nickel(ii) and zinc(ii) metal complexes have been synthesized and characterized by elemental analyses, molar conductances, magnetic moments, ir, nmr and electronic spectral data. these compounds have been screened for antibacterial activity against escherichia coli, bacillus subtillis, shigella flexneri, staphylococcus aureus, pseudomonas aeru ... | 2004 | 15648656 |
etiologic agents of dermatophyte infection in lebanon. | dermatophytes are common and cause important human fungal infections in many parts of the world, including lebanon. the prevalence of these fungi, however, tends to vary with time and geographic location. in our region, studies on the prevalence of dermatophytoses and the distribution of the various dermatophyte species involved are rare. in lebanon, only one study was published on this subject over the last forty years. | 2004 | 15884683 |
[dermatophytoses due to microsporum gypseum: report of eight cases and literature review]. | microsporum gypseum is a geophilic fungus infrequent agent of human dermatophytoses and world-wide in distribution. in cadiz, spain, between 1997 and 2003, a study of 133 positive cases showed that the fifth more isolated dermatophyte was m. gypseum (6.0%), followed by trichophyton mentagrophytes (24,8%), microsporun canis (24,6%), trichophyton rubrum (21,8%) y trichophyton violaceum (6,8%). during 2003 the infection due to this fungus has been repeatedly observed in our area (17.5%). we report ... | 2004 | 15709790 |
isolation of dermatophytes and other keratinophilic fungi from the vicinity of salt pan soils of mumbai, india. | soil samples from twenty salt pans and their vicinity around mumbai and thane were screened for the occurrence of keratinophilic fungi and related dermatophytes. ten species classified in six genera were recovered using horse hair as bait. the isolated species were reported in the following order of dominance: chrysosporium indicum (12.0%), microsporum gypseum complex (7.2%), c. tropicum (5.6%), c. state of ctenomyces serratus (4.0%), trichophyton terrestre (3.2%), malbranchea aurantiaca (2.4%), ... | 2004 | 15180153 |
etiology of tinea capitis in athens, greece -- a 6-year (1996-2001) retrospective study. | a total of 577 patients with tinea capitis have been diagnosed at the mycology laboratory of 'a. sygros' hospital of skin and venereal diseases, athens, greece between 1996 and 2001. from these patients, 100 were immigrants from balkan, near east and african countries. the vast majority of the patients (95%) were children, mainly at preschool and school age and only 5% were adults. zoophilic dermatophytes accounted for 86.5% followed by anthropophilic (12.4%) and geophilic (1.2%) dermatophytes. ... | 2004 | 15189185 |
keratinophilic fungi on feathers of pigeon in maharashtra, india. | results of a preliminary survey of keratinophilic fungi associated with feathers of pigeon on high rise buildings in thane district of maharashtra (india) are reported. a total of 100 samples were examined, of which 67 samples were positive for keratinophilic fungi. altogether 67 fungal strains belonging to 10 species of seven genera were isolated viz. chrysosporium indicum (24%), chrysosporium sp. (2%), chr. tropicum (8%), chrysosporium state of arthroderma tuberculatum (3%), chrysosporium stat ... | 2004 | 15189186 |
the epidemiology of microsporum canis infections in rijeka area, croatia. | the aim of the study was to analyze the microsporum canis infections in the rijeka area, croatia, observed between 1990 and 2001. a total of 724 cases of dermatophytosis caused by m. canis were diagnosed in 320 individuals with the tinea capitis and 404 with tinea corporis. the m. canis infections constituted 32.8% of all dermatophytes isolated during the study period. | 2004 | 15189188 |
kerion celsi in a newborn due to microsporum canis. | the present study deals with a case of a 40-day-old girl with kerion celsi caused by microsporum canis. the source of the infection were the parents who presented tinea corporis caused by m. canis. systemic treatment was carried out with terbinafine and complete recovery was achieved. tinea capitis is unusual in children during their first year of life and its evolution towards kerion is very rare in newborns. | 2004 | 15189191 |
disseminated dermatophytosis caused by microsporum gypseum in an aids patient: response to terbinafine and amorolfine. | a 51-year-old white male, native of rio de janeiro, brazil, with advanced aids and in chronic use of imidazoles for oral candidosis, presented erythematous, desquamative, pruriginous plaques of 1 month evolution on the trunk, inguinal/crural region, and lower limbs. the diagnosis of dermatophytosis was based on the isolation of microsporum gypseum from scales scraped from the skin lesions. the lesions regressed after 30 days treatment with itraconazole, 100 mg day(-1). after interruption of this ... | 2004 | 15189192 |
antifungal cobalt(ii), copper(ii), nickel(ii) and zinc(ii) complexes of furanyl-,thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins. | some novel cephalexin-derived furanyl, thiophenyl, pyrrolyl, salicylyl and pyridyl schiff's bases and their cobalt (ii), copper (ii), nickel (ii) and zinc (ii) complexes have been synthesized and studied for their antifungal properties against trichophyton longifusus, candida albicans, aspergillus flavus, microsporum canis, fusarium solani and candida glaberata. the presence of metal ions in the investigated schiff's base complexes reported here lead to significant antifungal activity, whereas t ... | 2004 | 15202498 |
development of an in vitro, isolated, infected spore testing model for disinfectant testing of microsporum canis isolates. | the isolated infected hair model is a commonly used technique to test the fungicidal efficacy of topical therapies against microsporum canis. the most commonly used model uses mats of infective hairs, and results from various laboratories have differed. the objectives of this study were to develop a method to produce spores for testing when only mycelial forms were available and to develop a semiquantitative testing method that used only infective spores from hairs, and not pooled hair samples f ... | 2004 | 15214954 |
generalized microsporum canis dermatophytosis in six yorkshire terrier dogs. | six yorkshire terrier dogs with generalized, chronic dermatophytosis caused by microsporum canis were seen over a 3-year period. specific tests showed that they also had concurrent leishmaniosis (four cases), leishmaniosis and ehrlichiosis (one case) or diabetes mellitus (one case). although specific therapy for these infectious diseases was instituted and the dogs were treated systemically and topically with appropriate antifungal drugs, only partial clinical resolution of the dermatophytosis w ... | 2004 | 15214955 |
intra- and interlaboratory study of a method for testing the antifungal susceptibilities of dermatophytes. | the national committee for clinical laboratory standards (nccls) m38-a standard for the susceptibility testing of conidium-forming filamentous fungi does not explicitly address the testing of dermatophytes. this multicenter study, involving six laboratories, investigated the mic reproducibility of seven antifungal agents tested against 25 dermatophyte isolates (5 blinded pairs of five dermatophyte species per site for a total of 300 tests), using the method of dermatophyte testing developed at t ... | 2004 | 15243047 |
(e)- and (z)-1,2,4-triazolylchromanone oxime ethers as conformationally constrained antifungals. | a series of 1,2,4-triazolylchromanone oxime ethers were synthesized and tested for in vitro antifungal activity. many of these derivatives exhibit high activity against candida albicans, saccharomyces cerevisiae, aspergillus niger and microsporum gypseum. | 2004 | 15246073 |
frequency and risk factors of dermatophytosis in students living in rural areas in eskişehir, turkey. | our study included 2384 students from five villages around eskişehir, turkey. we asked every student for their personal identification and also for their sanitation in order to get an idea about dermatophytosis. samples taken from suspicious lesion were collected and inoculated onto sabouraud dextrose agar slants. for identification of fungi which were grown, macroscopic appearance of colonies, microscopic examination and biochemical tests were used. we found suspicious lesions in 245 (10.3%) an ... | 2004 | 15281399 |
tinea capitis in kwa-zulu natal, south africa. | tinea capitis is the most common dermatophyte infection in children. the hair involvement can be classified as endothrix, ectothrix, or favus, and the clinical appearance is variable. the goal of this study was to determine the demography, etiology, and clinical patterns of tinea capitis in south africa. a prospective, cross-sectional study was conducted over a 1-year period. all cases were classified clinically and subject to wood light examination, microscopy, and culture. one hundred patients ... | 2004 | 15283786 |
itraconazole in the treatment of tinea capitis caused by microsporum canis: experience in a large cohort. | mycotic scalp infection caused by microsporum canis is one of the more recalcitrant disorders, with increasing incidence during the last decade. we report our experience with administration of itraconazole in 163 children (86 girls, 77 boys) with m. canis tinea capitis. fifty-five patients had previous treatment with terbinafine without success. in all children, the dosage of itraconazole was adjusted according to body weight, with 5 mg/kg/day given in a continuous regimen either as a capsule (1 ... | 2004 | 15283801 |
[statistical study of dermatomycosis for 30 years (1968-1997) in sendai national hospital]. | a statistical study on dermatomycoses for the 30 years from 1968 to 1997 in the dermatologic section of sendai national hospital was carried out with the following results. the total number of dermatomycosis patients was 14,259 and accounted for 9.59% of all new outpatients during this period. these cases of dermatomycoses were composed of the following: dermatophytoses 10,656, candidiasis 3,287, malassezia infection 566, sporothrichosis 20, aspergillosis 7, and chromomycosis 1. annual changes i ... | 2004 | 15284829 |
tinea capitis in a dermatology center in the city of fortaleza, brazil: the role of trichophyton tonsurans. | over a 3-year period (march 1999 to march 2002), 944 patients with scalp lesions attended a dermatology reference center in the city of fortaleza, ceará, brazil. clinical specimens were examined at the specialized medical mycology center, federal university of ceará, fortaleza-ce, brazil, to detect patients with tinea capitis. | 2004 | 15304180 |
[update on the diagnosis of dermatomycosis]. | dermatomycosis are mycotic diseases of skin caused by a few mycetes: dermatophytes, and some opportunistic fungi as malassezia, candida (not c. albicans), trichosporon, rhodutorula, cryptococcus or aspergillus, geotrichum, alternaria, etc. dermatophytes are a group of closely related filamentous fungi that invade keratinized tissue (skin, hair, nails) of humans and other animals and produce infection called dermatophytosis or ringworm or "tinea". the etiological agents of dermatophytosis are cla ... | 2004 | 15305713 |
dermatophytoses in split and dalmatia, croatia, 1996-2002. | the aim of the study was to investigate the epidemiology of dermatophyte infections in split and dalmatia county, croatia, between 1996 and 2002. of 5792 samples 1318 (23.8%) were positive. tinea corporis and tinea cruris were the most common types of dermatophytoses. microsporum canis (36.5%), trichophyton mentagrophytes (24.8%), and t. rubrum (21.5%) were the main etiologic factors. | 2004 | 15310333 |
dermatophytosis in children and adolescents in gdansk, poland. | during a 3-year period (1999-2001) a total of 94 cases of dermatophytosis were seen in patients from 0 to 18 years of age attending the department of dermatology, venerology and allergology of gdańsk medical university. mycoses were diagnosed on the basis of clinical picture and direct microscopy and were confirmed by positive cultures. the most frequent pathogens were microsporum canis (62%) and trichophyton rubrum (12%). the most often forms of dermatophytosis in children were tinea cutis glab ... | 2004 | 15310339 |
the novel azole r126638 is a selective inhibitor of ergosterol synthesis in candida albicans, trichophyton spp., and microsporum canis. | r126638 is a novel triazole with in vitro activity similar to that of itraconazole against dermatophytes, candida spp., and malassezia spp. in animal models of dermatophyte infections, r126638 showed superior antifungal activity. r126638 inhibits ergosterol synthesis in candida albicans, trichophyton mentagrophytes, trichophyton rubrum, and microsporum canis at nanomolar concentrations, with 50% inhibitory concentrations (ic(50)s) similar to those of itraconazole. the decreased synthesis of ergo ... | 2004 | 15328084 |
[identification of geophilic and zoophilic dermatophytes in siblings with tinea capitis. a pathogenic factor or contamination?]. | two siblings of african origin presented with multiple scaling patches and alopecia on the scalp four weeks after returning from a vacation in eritrea. direct koh examination revealed fungal elements; trichophyton mentagrophytes and trichophyton terrestre were identified in the fungal culture. we discuss the putative pathogenic role of both microorganisms in causing disease. although infection with microsporum canis currently accounts for almost fifty percent of all cases of tinea capitis in ger ... | 2004 | 15340708 |
a survey on the pathogenic fungi in soil samples of potted plants from sari hospitals, iran. | a total of 23 soil samples of potted plants was collected from hospitals in sari, iran. each sample contained approximately 200 g soil, taken from a depth of 0-10 cm of the pots. samples were analysed by two different methods. (1) culture on sabouraud's dextrose agar medium containing chloramphenicol (sc); cultured fungi were identified by macroscopic and microscopic characterization. (2) the hair-baiting technique (hbt) was used to isolate the keratinophilic fungi. after culture on sc medium, 1 ... | 2004 | 15350715 |
what is your diagnosis? dermatophytic pseudomycetoma. | 2004 | 15352405 | |
pcr and pcr-rflp techniques targeting the dna topoisomerase ii gene for rapid clinical diagnosis of the etiologic agent of dermatophytosis. | we have focused on the dna topoisomerase ii genes of several pathogenic fungi, and developed polymerase chain reaction (pcr) and pcr-restriction fragment length polymorphism (rflp) methods targeting this gene for identification of dermatophytes. | 2004 | 14757280 |
antimicrobial activity of hyptis ovalifolia towards dermatophytes. | the essential oil and the aqueous, hexane and methanolic fractions from hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of microsporum canis, 10 of m. gypseum, 20 of trichophyton rubrum and 20 of t. mentagrophytes. the extracts inhibited growth of the dermatophytes tested at different concentrations. the most biologically active was the essential oil from the leaves which inhibited 57 isolates (95%) at a concentration ... | 2004 | 14762526 |
monitoring of canine dermatophytosis by an immunodiagnostic method. | 2004 | 14765900 | |
multiplication of an ancestral gene encoding secreted fungalysin preceded species differentiation in the dermatophytes trichophyton and microsporum. | dermatophytes are human and animal pathogenic fungi which cause cutaneous infections and grow exclusively in the stratum corneum, nails and hair. in a culture medium containing soy proteins as sole nitrogen source a substantial proteolytic activity was secreted by trichophyton rubrum, trichophyton mentagrophytes and microsporum canis. this proteolytic activity was 55-75 % inhibited by o-phenanthroline, attesting that metalloproteases were secreted by all three species. using a consensus probe co ... | 2004 | 14766908 |
molecular typing study of the microsporum canis strains isolated from an outbreak of tinea capitis in a school. | tinea capitis is a dermatophyte infection of the scalp that occurs most often in prepubescent children. tinea capitis may be transmitted by shared use of contaminated hairbrush, by contact with fomites or by direct physical contact with an infected person. occasionally, outbreak of tinea capitis would happen under some special conditions. last year, we found an outbreak of tinea capitis in a school due to microsporum canis. in epidemiological study, we performed the prevalence survey to all of t ... | 2004 | 15008343 |
efficacy and tolerability of 8 weeks' treatment with terbinafine in children with tinea capitis caused by microsporum canis: a comparison of three doses. | tinea capitis caused by microsporum canis is the most common mycosis of the scalp in preschool and school-aged children in greece. | 2004 | 15009293 |
new treatments for tinea capitis. | tinea capitis, a dermatophyte infection involving the hair shaft on the scalp, is primarily a disease of preadolescent children. the predominant pathogen varies according to the geographical location. trichophyton tonsurans and microsporum canis account for the majority of infections in north america and certain parts of europe. the current standard of care for the treatment of tinea capitis in the usa is oral griseofulvin, but evidence is accumulating that some of the newer antifungal agents ma ... | 2004 | 15021047 |
antidermatophytic activity of extracts from psoralea corylifolia (fabaceae) correlated with the presence of a flavonoid compound. | extracts obtained from seeds of psoralea corylifolia showed several degrees of antifungal activity against trichophyton rubrum, trichophyton mentagrophytes, epidermophyton floccosum and microsporum gypseum by the disc diffusion method on a sabouraud dextrose agar (sda) medium. methanol extract of the seeds at 250 microg exhibited the maximum inhibition with a halo of 28 mm diameter. six different bands were obtained when the methanol extract was subjected to tlc. 13c nmr and mass spectra reveale ... | 2004 | 15036462 |
antibacterial and antifungal activity of syzygium jambolanum seeds. | the water and methanolic extracts of syzygium jambolanum seeds were examined for antibacterial and antifungal activity in vitro using the disc diffusion method, minimum inhibitory concentration, minimum bactericidal concentration and minimum fungicidal concentration. activity against gram positive bacteria (bacillus subtilis, staphylococcus aureus), gram negative bacteria (salmonella typhimurium, pseudomonas aeruginosa, klebsiella pneumoniae and escherichia coli) and fungal strains (candida albi ... | 2004 | 15036477 |
isolation of a promoter region of a secreted metalloprotease gene from microsporum canis. | mep3 of microsporum canis encodes a 43.5 kda extracellular keratinolytic metalloprotease, which is thought to be one of the virulence-related factors in dermatophytosis. in order to analyze the system underlying the regulation of mep3 gene expression, the 5'-upstream region was isolated by inverse pcr. the nucleotide sequence of a dna fragment of about 2.1 kb containing the coding region contains putative transcription factor binding sites and transcriptional initiation points. further analyses ... | 2004 | 14985633 |
therapeutic options in the treatment of tinea capitis. | tinea capitis is primarily a disease of pre-adolescent children. in north america and the uk, trichophyton tonsurans is responsible for > 90% of cases. microsporum canis is the predominant pathogen in certain parts of europe. the standard of care for the treatment of tinea capitis is oral griseofulvin and so far, it remains the only medication approved by the us fda for this condition. the newer oral antifungal agents, such as terbinafine, itraconazole and fluconazole, appear to be effective, sa ... | 2004 | 14996619 |
dermatology for the practicing allergist: tinea pedis and its complications. | tinea pedis is a chronic fungal infection of the feet, very often observed in patients who are immuno-suppressed or have diabetes mellitus. the practicing allergist may be called upon to treat this disease for various reasons. sometimes tinea infection may be mistaken for atopic dermatitis or allergic eczema. in other patients, tinea pedis may complicate allergy and asthma and may contribute to refractory atopic disease. patients with recurrent cellulitis may be referred to the allergist/immunol ... | 2004 | 15050029 |
antibacterial and antifugal mono- and di-substituted symmetrical and unsymmetrical triazine-derived schiff-bases and their transition metal complexes. | a new series of antibacterial and antifungal triazine-derived mono- and di-substituted (symmetrical and unsymmetrical) schiff-bases and their cobalt(ii), copper(ii), nickel(ii) and zinc(ii) metal complexes have been synthesized and characterized by their elemental analyses, molar conductances, magnetic moments and ir and electronic spectral measurements. ir spectra indicated the ligands to act as tridentate towards divalent metal ions via a trazine-n, the azomethine-n and, indole-nh and deproton ... | 2004 | 15449731 |
population structure and evolutionary origins of microsporum canis, m. ferrugineum and m. audouinii. | the recurrent evolutionary emergence of asexual lineages within sexual zoo- and anthropophilic dermatophyte species living in animal-frequented soil is likely to be triggered by changes in ecological niche, i.e., shifts of host animal. subsequent adaptation to the new host species is noted. sometimes geographic isolation or intrinsic host factors like human race may also play a role in speciation. in the present study, we elaborate concepts of speciation in dermatophytes using the microsporum ca ... | 2004 | 15450196 |
origins of onychomycosis. | onychomycosis, or tinea unguium, is generically thought of as a fungus infection of the nails characterized by thickening, splitting, roughening, and discoloration. this article discusses the origins of this condition as well as methods of classification and evaluation. | 2004 | 15450895 |
lung cancer epidemiology and risk factors in asia and africa. | in industrialised countries, lung cancer is the most common form of cancer among males and it is growing among females. for both sexes, rates reflect smoking behaviours. the pattern appears to be different in asia, particularly in china, where lung cancer rates in men reflect high smoking rates but high rates among non-smoking women appear to be related to other factors. the incidence of lung cancer is low in most african countries, but it is increasing. in addition to tobacco smoking, a number ... | 2004 | 15455588 |
derivatives of phosphate schiff base transition metal complexes: synthesis, studies and biological activity. | we report the synthesis and structural characterization of series of tetra- and hexacoordinate metal chelate complexes of phosphate schiff base ligands having the general composition lmx(n).h(2)o and l(2)mx(n) (l=phosphate schiff base ligand; m=ag(+), mn(2+), cu(2+), zn(2+), cd(2+), hg(2+), or fe(3+) and x=no(3)(-), br(-) or cl(-)). the structure of the prepared compounds was investigated using elemental analysis, ir, 1h and 31p nmr, uv-vis, mass spectra, solid reflectance, magnetic susceptibili ... | 2004 | 14670488 |
evaluation of immunogenicity and protective efficacy of a microsporum canis metalloprotease subunit vaccine in guinea pigs. | in order to identify protective immunogens against microsporum canis infection, a purified recombinant keratinolytic metalloprotease (r-mep3) was tested as a subunit vaccine in experimentally infected guinea pigs. both humoral and cellular specific immune responses developing towards r-mep3 were evaluated, by enzyme-linked immunosorbent assay and by in vitro lymphocyte transformation tests respectively. vaccination induced a strong antibody response, and a significant but transient lymphoprolife ... | 2004 | 14734190 |
tinea barbae (tinea sycosis): experience with nine cases. | tinea barbae is a rare dermatophytosis that affects the hair and hair follicles of the beard and mustache. this paper presents 9 cases of tinea barbae observed over an 18-year period of time and classified as follows: 1 was superficial and 8 were deep (6 folliculitis-like and 2 kerion-like). most of the cases (4) were associated with topical steroid therapy, others with pet contact (3 cases) and one with diabetes. the causal agents isolated were: trichophyton rubrum in 3; microsporum canis in 3; ... | 2003 | 14739517 |
tinea capitis among children and adolescents in the farwaniya region of kuwait. | analysis of 325 patients (182 males, 143 females) of mycologically proven tinea capitis (tc) seen over a period of two years from january 2001--december 2002 in the farwaniya region of kuwait is presented in this study. the age range was 8 months to 17 years. peak incidence was observed in the 3-14 year age group (79.6%). positive family history and contact with pets were noted in 22% and 36.7% of the cases, respectively. the non-inflammatory 'gray patch' variety was the most common clinical typ ... | 2003 | 14739518 |
dermatophyte agents in the city of são paulo, from 1992 to 2002. | dermatophytosis are superficial mycoses caused by fungi that can invade stratum corneum and keratinized tissues. in order to study the frequency of dermatophytes species and the clinical manifestations caused by these fungi, in são paulo, sp, brazil, the authors analyzed cultures isolated at the mycology laboratory from a selected population (15,300 out-patients of the hospital das clínicas, department of dermatology, faculty of medicine of university of são paulo) from january 1992 to june 2002 ... | 2003 | 14743665 |
a recombinant 31.5 kda keratinase and a crude exo-antigen from microsporum canis fail to protect against a homologous experimental infection in guinea pigs. | a microsporum canis recombinant 31.5 kda keratinase and a m. canis crude exo-antigen were tested as vaccines in an experimental infection model in guinea pigs. animals were vaccinated subcutaneously three times at two-week intervals with either the keratinase, the exo-antigen or the adjuvant alone. cutaneous challenge was performed blindly. both humoral and cellular-specific immune responses to m. canis antigens were evaluated every 14 days, while a blind evaluation of clinical lesion developmen ... | 2003 | 14678442 |
epidemiology of dermatophytoses in an area south of tehran, iran. | dermatophyte infections have been considered to be a major public health problem in many parts of the world. the aim of this study was to identify the etiological and epidemiological factors of dermatophyte infections in an area south of tehran. a total of 1254 patients suspected to have dermatophytic lesions were examined over a period of three years (1999-2001). material collected from skin, hair, and nails was submitted to direct microscopic examination using koh, cultured in sabouraud dextro ... | 2003 | 14682452 |
occurrence of dermatomycoses and in-vitro therapeutic efficacy of three antifungal drugs on the growth of epidermophyton floccosum. | the occurrence of dermatomycoses and the in-vitro therapeutic efficacy of some antifungal agents on dermatomycotic organisms were investigated. of the 550 primary school children screened, the incidence was one hundred (18%), 70 were males (representing 20% of the males screened) and 30 females (15% of the females sampled). the differences between male and female prevalence were insignificant. three species of dermatophytes were isolated and identified. these were microsporum canis, trichophyton ... | 2003 | 14682454 |
high rate of microsporum canis feline and canine dermatophytoses in northeast brazil: epidemiological and diagnostic features. | over a one year period (november 2000-december 2001), clinical specimens from 189 dogs and 38 cats, from the city of fortaleza, ceará, brazil, were examined at the specialized medical mycology center at the federal university of ceará to detect animals with dermatophytoses. the mycological analyses were conducted by direct microscopy and by fungal culture on sabouraud agar, sabouraud chloramphenicol agar and mycosel agar. dermatophytes were isolated from 27 of the 189 (14.3%) canine specimens an ... | 2003 | 14682455 |
humoral and cellular immune response to a microsporum canis recombinant keratinolytic metalloprotease (r-mep3) in experimentally infected guinea pigs. | in order to better understand the host-fungus relationship in microsporum canis dermatophytosis and to identify major fungal antigens, the immune response to a crude exoantigen preparation and to a purified recombinant keratinolytic metalloprotease (r-mep3) was evaluated in guinea pigs experimentally infected with m. canis. humoral and cellular immune responses were assessed from day 0 to day 57 post-infection (pi), the former by enzyme-linked immunosorbent assay (elisa) and the latter via a lym ... | 2003 | 14725323 |
constituents of the argentinian medicinal plant baccharis grisebachii and their antimicrobial activity. | the resinous exudate of baccharis grisebachii which is used to treat ulcers, burns, and skin sores in argentina showed activity towards dermatophytes and bacteria. two diterpenes, eight p-coumaric acid derivatives, and two flavones were isolated from the exudate and the structures elucidated by spectroscopic methods. 3-prenyl-p-coumaric acid and 3,5-diprenyl-p-coumaric acid were active towards epidermophyton floccosum and trichophyton rubrum with mics of 50 and 100-125 microg/ml, respectively. t ... | 2003 | 14522435 |
species-identification of dermatophytes trichophyton, microsporum and epidermophyton by pcr and pcr-rflp targeting of the dna topoisomerase ii genes. | we have focused on the dna topoisomerase ii genes of pathogenic fungi and have previously applied polymerase chain reaction (pcr)-based identification of several species including the some of the major dermatophyte species. | 2003 | 14527738 |
[epidemiological survey of dermatophytosis in spain (april-june 2001)]. | a three-month (april-june 2001) cross-sectional study was designed to assess the epidemiological profile of dermatophytosis in spain. | 2003 | 14572379 |
[in vitro activity of voriconazole and three other antifungal agents against dermatophytes]. | the increase in infections due to dermatophytes in recent years led us to study the effectiveness of new antifungal formulations against these microorganisms. | 2003 | 14572380 |
[current types of human dermatophytoses transmitted from animals]. | microsporum canis, trichophyton verrucosum and t. mentagrophytes are the most common dermatophytes isolated from human and animals. m. canis infection in human is closely related to companion animals such as cats and dogs. according to a recent epidemiological survey in japan, human m. canis infection is decreasing. t. verrucosum is usually transmitted from cows to human. t. verrucosum infection in human is not restricted to daily farming prefectures, however, suggesting that this species has al ... | 2003 | 14615787 |
epidemiology of dermatophyte infection in auckland, new zealand. | this report describes the epidemiology of culture-proven dermatophyte infection in auckland, new zealand. the authors undertook a retrospective review of laboratory data for the period from june 1999 to july 2002. there were 10 004 dermatophyte isolates. the most common isolates were trichophyton rubrum (69%) and trichophyton mentagrophytes (19%). microsporum canis was mainly isolated from children. the prevalence of t. mentagrophytes increased with patient age (p < 0.001). trichophyton rubrum w ... | 2003 | 14616492 |
tinea capitis due to microsporum audouinii in malta. | we describe a case of tinea capitis in a 4-year-old boy caused by microsporum audouinii var. langeronii. this is the first recorded case of tinea capitis due to this dermatophyte in the maltese islands. | 2003 | 14622396 |
environmental detection of microsporum canis arthrospores in the households of infected cats and dogs. | microsporum canis is the dermatophyte most frequently recovered from canine and feline ringworm cases. the household environment can be contaminated both by symptomatic animals and through asymptomatic m canis carriage, resulting in a potential human health risk. the load of m canis arthrospores was determined in households harbouring infected pets, in order to evaluate the infectivity of the animals versus the environment. the environments inhabited by 30 symptomatic animals (21 cats and 9 dogs ... | 2003 | 14623201 |
action mechanisms of modern antifungal agents and resulting problems in the management of onychomycosis. | successful treatment of onychomycosis in the infection site depends not only on achieving the minimal inhibitory concentration (mic) of the antifungal agent, usually determined on fresh, proliferating fungal strains, but also on the effectivity against fungal spores dormant in nail keratin. ciclopiroxolamine and terbinafine were investigated for their fungicidal properties against proliferating and dormant dermatophyte strains. while ciclopiroxolamine was 100% effective against trichophyton ment ... | 2003 | 14641625 |
dermal mass aspirate from a persian cat. | a 1-year-old spayed female persian cat with alopecia and weight loss had numerous variably ulcerated dermal nodules. cytologic examination of an aspirate of one of the nodules revealed pyogranulomatous inflammation along with septate hyphae and basophilic round bodies, 0.5-1.0 microm in diameter, surrounded by a thin clear halo (arthrospores). the cytologic diagnosis was dermatophytic pseudomycetoma. histologically, there were dermal granulomas containing poorly staining, septate hyphae with bul ... | 2003 | 14655108 |
[tricky differential diagnosis: peri-oral inflammation]. | 2003 | 14655504 | |
[dermatophyte infection and colonization in dogs from south santiago, chile]. | our main aim was to determine the dermatophyte infection and colonization prevalence in canines from south santiago, chile. we studied 241 dogs, 121 of them presented cutaneous lesions suggestive of dermatophytosis and the other 120 were free from lesions and were considered clinically healthy. dermatophytes were isolated from the lesions of 48.8% of animals with cutaneous diseases and from 5% of healthy dogs. microsporum canis was the principal species isolated with a frequency of 98.3% from de ... | 2003 | 15456352 |
[canine onychomycosis produced by microsporum gypseum. a case report]. | one case of severe canine onychomycosis is described. the aetiological agent was identified as microsporum gypseum. the incidence of this fungus in this kind of pathology is discussed, with special attention to the successful treatment with topic enilconazole and systemic griseofulvin. | 2003 | 15456357 |
in vitro antifungal activity of sertaconazole against 309 dermatophyte clinical isolates. | three hundred and nine strains belonging to 11 species of dermatophyte moulds were tested against sertaconazole following mainly the national committee for clinical laboratory standards (m38-p) for filamentous fungi. however, several important factors such as the temperature (28 degrees c vs 35 degrees c) and time of incubation (4-10 d vs 21-74 h), have been modified. sertaconazole was active against all the clinically important dermatophyte moulds involved in human infections tested. overall ge ... | 2003 | 14998079 |
[tinea capitis in children from goiânia, brazil]. | during the period january 1999 to july 2002 a total de 164 cases of tinea capitis were diagnosed by mycological examination in instituto de patologia tropical e saúde pública of the universidade federal de goiás. of the 164 patients 94 (57.3%) were males, with an age of 3 months to 13 years. laboratory studies were performed by direct examination with 20% koh and cultivated on mycobiotic agar medium and sabouraud dextrose agar with chloramphenicol. the following species were identified: microspo ... | 2003 | 15049102 |
antifungal activity of boerhavia diffusa against some dermatophytic species of microsporum. | various extracts petroleum ether, chloroform, ethyl acetate and ethyl alcohol) of aerial and root parts of boerhavia diffusa was sereened for antitungal activity (inhibition in sporulation) against dermatophytic fungi microsporum gypseum, m. fulvum and m. canis by using broth dilution method. extracts of aerial part not show any noticeable antifungal activity. ethyl acetate extract of root part of the plant was found to be most effective of against target fungal species. the maximum inhibition o ... | 2003 | 16281821 |